#METABOLOMICS WORKBENCH alhughes3_20210722_081823 DATATRACK_ID:2764 STUDY_ID:ST001901 ANALYSIS_ID:AN003092 VERSION 1 CREATED_ON 02-08-2024 #PROJECT PR:PROJECT_TITLE Mitochondrial-Derived Compartments Facilitate Cellular Adaptation to Amino Acid PR:PROJECT_TITLE Stress PR:PROJECT_SUMMARY Amino acids are essential building blocks of life. However, increasing evidence PR:PROJECT_SUMMARY suggests that elevated amino acids cause cellular toxicity associated with PR:PROJECT_SUMMARY numerous metabolic disorders. How cells cope with elevated amino acids remains PR:PROJECT_SUMMARY poorly understood. Here, we show that a previously identified cellular PR:PROJECT_SUMMARY structure, the mitochondrial-derived compartment (MDC), functions to protect PR:PROJECT_SUMMARY cells from amino acid stress. In response to amino acid elevation, MDCs are PR:PROJECT_SUMMARY generated from mitochondria, where they selectively sequester and deplete SLC25A PR:PROJECT_SUMMARY nutrient carriers and their associated import receptor Tom70 from the organelle. PR:PROJECT_SUMMARY Generation of MDCs promotes amino acid catabolism, and their formation occurs PR:PROJECT_SUMMARY simultaneously with transporter removal at the plasma membrane via the PR:PROJECT_SUMMARY multi-vesicular body (MVB) pathway. Combined loss of vacuolar amino acid PR:PROJECT_SUMMARY storage, MVBs and MDCs renders cells sensitive to high amino acid stress. Thus, PR:PROJECT_SUMMARY we propose that MDCs operate as part of a coordinated cell network that PR:PROJECT_SUMMARY facilitates amino acid homoeostasis through post-translational nutrient PR:PROJECT_SUMMARY transporter remodeling. PR:INSTITUTE University of Utah School of Medicine PR:DEPARTMENT Biochemistry PR:LABORATORY Hughes Lab PR:LAST_NAME Hughes PR:FIRST_NAME Adam PR:ADDRESS 15 N Medical Drive East, RM 4100, Salt Lake City, UT, 84112, USA PR:EMAIL hughes@biochem.utah.edu PR:PHONE 8015812481 PR:DOI http://dx.doi.org/10.21228/M83X4N #STUDY ST:STUDY_TITLE Mitochondrial-Derived Compartments Facilitate Cellular Adaptation to Amino Acid ST:STUDY_TITLE Stress ST:STUDY_SUMMARY Amino acids are essential building blocks of life. However, increasing evidence ST:STUDY_SUMMARY suggests that elevated amino acids cause cellular toxicity associated with ST:STUDY_SUMMARY numerous metabolic disorders. How cells cope with elevated amino acids remains ST:STUDY_SUMMARY poorly understood. Here, we show that a previously identified cellular ST:STUDY_SUMMARY structure, the mitochondrial-derived compartment (MDC), functions to protect ST:STUDY_SUMMARY cells from amino acid stress. In response to amino acid elevation, MDCs are ST:STUDY_SUMMARY generated from mitochondria, where they selectively sequester and deplete SLC25A ST:STUDY_SUMMARY nutrient carriers and their associated import receptor Tom70 from the organelle. ST:STUDY_SUMMARY Generation of MDCs promotes amino acid catabolism, and their formation occurs ST:STUDY_SUMMARY simultaneously with transporter removal at the plasma membrane via the ST:STUDY_SUMMARY multi-vesicular body (MVB) pathway. Combined loss of vacuolar amino acid ST:STUDY_SUMMARY storage, MVBs and MDCs renders cells sensitive to high amino acid stress. Thus, ST:STUDY_SUMMARY we propose that MDCs operate as part of a coordinated cell network that ST:STUDY_SUMMARY facilitates amino acid homoeostasis through post-translational nutrient ST:STUDY_SUMMARY transporter remodeling. ST:INSTITUTE University of Utah School of Medicine ST:DEPARTMENT Biochemistry ST:LABORATORY Hughes Lab ST:LAST_NAME Hughes ST:FIRST_NAME Adam ST:ADDRESS 15 N Medical Drive East, RM 4100, Salt Lake City, UT, 84112, USA ST:EMAIL hughes@biochem.utah.edu ST:PHONE 8015812481 ST:SUBMIT_DATE 2021-07-22 #SUBJECT SU:SUBJECT_TYPE Yeast SU:SUBJECT_SPECIES Saccharomyces cerevisiae SU:TAXONOMY_ID 4932 #SUBJECT_SAMPLE_FACTORS: SUBJECT(optional)[tab]SAMPLE[tab]FACTORS(NAME:VALUE pairs separated by |)[tab]Additional sample data SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_6A Genotype:gem1 knockout | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_6A.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_6B Genotype:gem1 knockout | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_6B.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_6C Genotype:gem1 knockout | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_6C.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_6D Genotype:gem1 knockout | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_6D.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_2A Genotype:gem1 knockout | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_2A.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_2B Genotype:gem1 knockout | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_2B.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_2C Genotype:gem1 knockout | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_2C.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_2D Genotype:gem1 knockout | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_2D.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_11 Genotype:gem1 knockout | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_11.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_17 Genotype:gem1 knockout | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_17.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_23 Genotype:gem1 knockout | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_23.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_5a Genotype:gem1 knockout | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_5a.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_11 Genotype:gem1 knockout | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_11.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_17 Genotype:gem1 knockout | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_17.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_23 Genotype:gem1 knockout | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_23.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_5 Genotype:gem1 knockout | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_5.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_10 Genotype:gem1 knockout | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_10.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_16 Genotype:gem1 knockout | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_16.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_22 Genotype:gem1 knockout | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_22.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_4 Genotype:gem1 knockout | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_4.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_10 Genotype:gem1 knockout | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_10.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_16 Genotype:gem1 knockout | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_16.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_22 Genotype:gem1 knockout | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_22.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_4 Genotype:gem1 knockout | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_4.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_12 Genotype:gem1 knockout | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_12.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_18 Genotype:gem1 knockout | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_18.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_24 Genotype:gem1 knockout | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_24.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_5 Genotype:gem1 knockout | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_5.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_12 Genotype:gem1 knockout | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_12.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_18 Genotype:gem1 knockout | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_18.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_24 Genotype:gem1 knockout | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_24.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_6 Genotype:gem1 knockout | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_6.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_4D Genotype:gem1 vps27 double knockout | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_4D.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_8A Genotype:gem1 vps27 double knockout | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_8A.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_8B Genotype:gem1 vps27 double knockout | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_8B.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_8C Genotype:gem1 vps27 double knockout | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_8C.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_8D Genotype:gem1 vps27 double knockout | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_8D.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_4A Genotype:gem1 vps27 double knockout | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_4A.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_4B Genotype:gem1 vps27 double knockout | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_4B.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_4C Genotype:gem1 vps27 double knockout | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_4C.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_QC5 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_QC5.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_QC6 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_QC6.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_QC7 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_QC7.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_QC8 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_QC8.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_QC1 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_QC1.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_QC2 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_QC2.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_QC3 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_QC3.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_QC4 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_QC4.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_QC1 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_QC1.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_QC2 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_QC2.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_QC3 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_QC3.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_QC4 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_QC4.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_QC1 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_QC1.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_QC2 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_QC2.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_QC3 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_QC3.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_QC4 Genotype:Pooled QC sample | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_QC4.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_PB4 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_PB4.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_PB5 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_PB5.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_PB6 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_PB6.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_PB1 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_PB1.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_PB2 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_PB2.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_PB3 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_PB3.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_PB4 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_PB4.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_PB1 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_PB1.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_PB2 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_PB2.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_PB3 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_PB3.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_PB4 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_PB4.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_PB1 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_PB1.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_PB2 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_PB2.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_PB3 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_PB3.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_PB4 Genotype:Process blank | Media:N/A | Treatment:N/A RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_PB4.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_7A Genotype:vps27 knockout | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_7A.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_7B Genotype:vps27 knockout | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_7B.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_7C Genotype:vps27 knockout | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_7C.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_7D Genotype:vps27 knockout | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_7D.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_3A Genotype:vps27 knockout | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_3A.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_3B Genotype:vps27 knockout | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_3B.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_3C Genotype:vps27 knockout | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_3C.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_3D Genotype:vps27 knockout | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_3D.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_34 Genotype:wild-type | Media:MinD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_34.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_43 Genotype:wild-type | Media:MinD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_43.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_52 Genotype:wild-type | Media:MinD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_52.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_5A Genotype:wild-type | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_5A.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_5B Genotype:wild-type | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_5B.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_5C Genotype:wild-type | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_5C.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_5D Genotype:wild-type | Media:SD+Leucine | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_5D.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_1A Genotype:wild-type | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_1A.D; Experiment identifier=MDCY-205; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_1B Genotype:wild-type | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_1B.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_1C Genotype:wild-type | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_1C.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200818_7200_20to1_Yeast_1D Genotype:wild-type | Media:SD+Leucine | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_1D.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_31 Genotype:wild-type | Media:SD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_31.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_40 Genotype:wild-type | Media:SD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_40.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_49 Genotype:wild-type | Media:SD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_49.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_14 Genotype:wild-type | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_14.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_2 Genotype:wild-type | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_2.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_20 Genotype:wild-type | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_20.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_8 Genotype:wild-type | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_8.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_14 Genotype:wild-type | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_14.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_2 Genotype:wild-type | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_2.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_20 Genotype:wild-type | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_20.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_8 Genotype:wild-type | Media:YPAD | Treatment:ConcA RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_8.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_28 Genotype:wild-type | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_28.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_37 Genotype:wild-type | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_37.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20190522_5977b_10to1_Yeast_46 Genotype:wild-type | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_46.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3 SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_1 Genotype:wild-type | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_1.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_13 Genotype:wild-type | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_13.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_19 Genotype:wild-type | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_19.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_7 Genotype:wild-type | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_7.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_1 Genotype:wild-type | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_1.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_13 Genotype:wild-type | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_13.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_19 Genotype:wild-type | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_19.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_7 Genotype:wild-type | Media:YPAD | Treatment:DMSO RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_7.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_15 Genotype:wild-type | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_15.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_21 Genotype:wild-type | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_21.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_3 Genotype:wild-type | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_3.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_9 Genotype:wild-type | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_9.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_15 Genotype:wild-type | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_15.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_21 Genotype:wild-type | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_21.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_3 Genotype:wild-type | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_3.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E SUBJECT_SAMPLE_FACTORS - Hughes_Schuler_20200825_7200_20to1_MSTFA_9 Genotype:wild-type | Media:YPAD | Treatment:Rap RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_9.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E #COLLECTION CO:COLLECTION_SUMMARY See STAR methods file CO:COLLECTION_PROTOCOL_FILENAME STAR_methods.pdf CO:SAMPLE_TYPE Yeast cells #TREATMENT TR:TREATMENT_SUMMARY See STAR Methods file TR:TREATMENT_PROTOCOL_FILENAME STAR_methods.pdf #SAMPLEPREP SP:SAMPLEPREP_SUMMARY See STAR Methods file SP:SAMPLEPREP_PROTOCOL_FILENAME STAR_methods.pdf #CHROMATOGRAPHY CH:INSTRUMENT_NAME Agilent 5977B CH:COLUMN_NAME Phenomenex Zebron ZB-WAXplus (30m x 0.25mm,0.25um) CH:CHROMATOGRAPHY_TYPE GC #ANALYSIS AN:ANALYSIS_TYPE MS #MS MS:INSTRUMENT_NAME Agilent 5977B MS:INSTRUMENT_TYPE Single quadrupole MS:MS_TYPE EI MS:MS_COMMENTS N/A MS:ION_MODE POSITIVE #MS_METABOLITE_DATA MS_METABOLITE_DATA:UNITS area under the curve MS_METABOLITE_DATA_START Samples Hughes_Schuler_20190522_5977b_10to1_Yeast_QC5 Hughes_Schuler_20190522_5977b_10to1_Yeast_QC6 Hughes_Schuler_20190522_5977b_10to1_Yeast_QC7 Hughes_Schuler_20190522_5977b_10to1_Yeast_QC8 Hughes_Schuler_20190522_5977b_10to1_Yeast_PB4 Hughes_Schuler_20190522_5977b_10to1_Yeast_PB5 Hughes_Schuler_20190522_5977b_10to1_Yeast_PB6 Hughes_Schuler_20190522_5977b_10to1_Yeast_34 Hughes_Schuler_20190522_5977b_10to1_Yeast_43 Hughes_Schuler_20190522_5977b_10to1_Yeast_52 Hughes_Schuler_20190522_5977b_10to1_Yeast_31 Hughes_Schuler_20190522_5977b_10to1_Yeast_40 Hughes_Schuler_20190522_5977b_10to1_Yeast_49 Hughes_Schuler_20190522_5977b_10to1_Yeast_28 Hughes_Schuler_20190522_5977b_10to1_Yeast_37 Hughes_Schuler_20190522_5977b_10to1_Yeast_46 Factors Genotype:Pooled QC sample | Media:N/A | Treatment:N/A Genotype:Pooled QC sample | Media:N/A | Treatment:N/A Genotype:Pooled QC sample | Media:N/A | Treatment:N/A Genotype:Pooled QC sample | Media:N/A | Treatment:N/A Genotype:Process blank | Media:N/A | Treatment:N/A Genotype:Process blank | Media:N/A | Treatment:N/A Genotype:Process blank | Media:N/A | Treatment:N/A Genotype:wild-type | Media:MinD | Treatment:DMSO Genotype:wild-type | Media:MinD | Treatment:DMSO Genotype:wild-type | Media:MinD | Treatment:DMSO Genotype:wild-type | Media:SD | Treatment:DMSO Genotype:wild-type | Media:SD | Treatment:DMSO Genotype:wild-type | Media:SD | Treatment:DMSO Genotype:wild-type | Media:YPAD | Treatment:DMSO Genotype:wild-type | Media:YPAD | Treatment:DMSO Genotype:wild-type | Media:YPAD | Treatment:DMSO 1_6-anhydro-glucose 6332.0000 8739.0000 8575.0000 13142.0000 775.0000 491.0000 6397.0000 7488.0000 8177.0000 6265.0000 2599.0000 5217.0000 7579.0000 10189.0000 8802.0000 1-monomyristin 1226.0000 817.0000 781.0000 714.0000 1115.0000 1268.0000 608.0000 601.0000 1869.0000 2713.0000 5728.0000 1-octadecene 3058.0000 4541.0000 8924.0000 8988.0000 3475.0000 2812.0000 2772.0000 5257.0000 3951.0000 5078.0000 4213.0000 6430.0000 5558.0000 1-Palmitoylglycerol 1374.0000 101.0000 2486.0000 3904.0000 1263.0000 2029.0000 1537.0000 5798.0000 2682.0000 3512.0000 2171.0000 286.0000 1921.0000 3043.0000 1-Steroylglycerol 16932.0000 17108.0000 20656.0000 36720.0000 11202.0000 13913.0000 23052.0000 19264.0000 15303.0000 18764.0000 16456.0000 13244.0000 17587.0000 17478.0000 22128.0000 16254.0000 2^3^-Bisphosphoglycerate 2934.0000 1435.0000 390.0000 641.0000 809.0000 292.0000 1364.0000 2-Hydroxybenzoic acid 1342.0000 860.0000 1556.0000 451.0000 537.0000 889.0000 1188.0000 565.0000 108.0000 923.0000 323.0000 2-Hydroxybutyric acid 2 58772.0000 66513.0000 63533.0000 67625.0000 65043.0000 51026.0000 27285.0000 59888.0000 45728.0000 55414.0000 52620.0000 50720.0000 56622.0000 66976.0000 84740.0000 53209.0000 2-Hydroxyglutaric acid 1 1903.0000 3485.0000 4616.0000 6799.0000 5067.0000 4807.0000 2635.0000 3692.0000 1457.0000 1637.0000 1530.0000 4538.0000 6247.0000 7256.0000 2-ketoglutarate 744.0000 620.0000 844.0000 130.0000 756.0000 1319.0000 1036.0000 673.0000 2-Ketoisocaproic acid 1454.0000 1382.0000 2109.0000 1535.0000 3450.0000 4551.0000 627.0000 1071.0000 1611.0000 657.0000 3904.0000 2-monopalmitoylglycerol 1889.0000 2545.0000 2867.0000 8779.0000 1355.0000 1657.0000 2267.0000 2023.0000 3848.0000 1525.0000 4308.0000 2981.0000 2765.0000 3247.0000 4387.0000 2-Steroylglycerol 2647.0000 590.0000 189.0000 1135.0000 3-hydroxybutyric acid 3774.0000 4597.0000 5327.0000 10675.0000 2481.0000 593.0000 4559.0000 4991.0000 3000.0000 1289.0000 9096.0000 21934.0000 10940.0000 3-Phosphoglyceric acid 917.0000 839.0000 866.0000 187.0000 377.0000 342.0000 89.0000 369.0000 165.0000 246.0000 876.0000 211.0000 174.0000 4-Hydroxyproline 1 2152.0000 3173.0000 3660.0000 13503.0000 2950.0000 11469.0000 3065.0000 4-Hydroxyproline 2 3629.0000 2516.0000 4031.0000 3015.0000 5-hydroxytryptophan 1071.0000 1181.0000 122.0000 153.0000 415.0000 1281.0000 2200.0000 1444.0000 656.0000 841.0000 626.0000 Adenine 33347.0000 50027.0000 61167.0000 92806.0000 671.0000 854.0000 944.0000 53481.0000 37591.0000 33423.0000 28724.0000 24548.0000 25082.0000 29490.0000 47258.0000 43014.0000 Adenosine 16188.0000 11517.0000 15517.0000 31274.0000 993.0000 271.0000 13309.0000 21016.0000 20759.0000 6508.0000 8834.0000 8472.0000 38216.0000 62813.0000 51449.0000 Adenosine monophosphate 26696.0000 27931.0000 37672.0000 61085.0000 383.0000 46751.0000 29638.0000 32383.0000 31403.0000 31471.0000 43272.0000 52293.0000 66050.0000 61046.0000 Adipic acid 683.0000 1109.0000 1319.0000 579.0000 649.0000 897.0000 1149.0000 810.0000 621.0000 579.0000 690.0000 236.0000 396.0000 Allantoin 1202.0000 261.0000 645.0000 933.0000 367.0000 2121.0000 116.0000 419.0000 alpha-D-glucosamine 1-phosphate 926.0000 446.0000 2729.0000 Aminoadipic acid 3762.0000 4728.0000 5795.0000 8038.0000 229.0000 167.0000 39939.0000 31469.0000 27729.0000 1790.0000 1328.0000 3099.0000 3626.0000 4297.0000 2971.0000 Arachidic acid 468.0000 593.0000 727.0000 65.0000 172.0000 956.0000 Arachidonic Acid 1822.0000 906.0000 2074.0000 6234.0000 202.0000 567.0000 284.0000 2054.0000 1296.0000 1857.0000 540.0000 1331.0000 azelaic acid 8231.0000 7250.0000 10704.0000 9990.0000 2979.0000 1737.0000 2305.0000 10117.0000 5664.0000 9371.0000 4604.0000 4467.0000 7293.0000 7389.0000 11140.0000 11752.0000 Benzoic acid 1305.0000 547.0000 137.0000 416.0000 Benzoquinone 970.0000 196.0000 2295.0000 1101.0000 3040.0000 3592.0000 Beta-Alanine 29227.0000 44509.0000 51899.0000 67482.0000 168.0000 381.0000 552.0000 187380.0000 160607.0000 138929.0000 670.0000 621.0000 1248.0000 2380.0000 941.0000 Beta-Glycerophosphoric acid 156.0000 125.0000 224.0000 196.0000 195.0000 219.0000 146.0000 105.0000 155.0000 Beta-lactate 18009.0000 28548.0000 37214.0000 41708.0000 21993.0000 16884.0000 21805.0000 29644.0000 26715.0000 22917.0000 24147.0000 16459.0000 21672.0000 43613.0000 54158.0000 55515.0000 Beta-Sitosterol 988.0000 1582.0000 2384.0000 2880.0000 2717.0000 Capric acid 13400.0000 13803.0000 16430.0000 20514.0000 8903.0000 10019.0000 18386.0000 12871.0000 16592.0000 7172.0000 7184.0000 17364.0000 11531.0000 18964.0000 45915.0000 15383.0000 Cellobiose 763.0000 658.0000 352.0000 89.0000 499.0000 4191.0000 5122.0000 10681.0000 Cholesterol 77176.0000 65053.0000 54598.0000 176511.0000 910.0000 49107.0000 59828.0000 65518.0000 83174.0000 60835.0000 62974.0000 62926.0000 158469.0000 51568.0000 cis-Aconitic acid 866.0000 392.0000 322.0000 1018.0000 211.0000 Citric acid 111869.0000 163842.0000 208721.0000 281446.0000 373.0000 375.0000 24372.0000 14228.0000 11130.0000 17386.0000 10404.0000 13733.0000 103584.0000 164537.0000 104524.0000 Creatinine 4976.0000 6246.0000 7884.0000 21320.0000 6078.0000 7654.0000 8070.0000 4551.0000 5678.0000 5799.0000 4135.0000 6971.0000 32687.0000 11811.0000 Cystathionine 3470.0000 5144.0000 15354.0000 678.0000 459.0000 490.0000 3297.0000 4720.0000 2774.0000 3341.0000 2291.0000 4885.0000 4849.0000 d4-succinate 5136.0000 12429.0000 6508.0000 3530.0000 4899.0000 13044.0000 7431.0000 16410.0000 12135.0000 15291.0000 4617.0000 4104.0000 5849.0000 3153.0000 9068.0000 4302.0000 Dehydroascorbic acid 4438.0000 5883.0000 7182.0000 8412.0000 351.0000 3386.0000 3136.0000 2775.0000 874.0000 3279.0000 2702.0000 delta Amino Levulinic acid 14806.0000 16628.0000 24780.0000 21073.0000 1594.0000 1661.0000 2220.0000 5463.0000 6856.0000 16528.0000 10826.0000 13033.0000 11593.0000 26191.0000 24214.0000 D-Fructose 1 10083.0000 7194.0000 3214.0000 7259.0000 273.0000 2723.0000 1145.0000 4500.0000 3391.0000 7005.0000 7100.0000 8417.0000 13374.0000 2582.0000 D-Fructose 2 5865.0000 2633.0000 8533.0000 7599.0000 213.0000 180.0000 29550.0000 5391.0000 17294.0000 6005.0000 4245.0000 9703.0000 5170.0000 9606.0000 2966.0000 D-Galactose 1656516.0000 1692248.0000 2376936.0000 3234528.0000 972.0000 1031.0000 2354.0000 2143535.0000 1415752.0000 10924720.0000 2436460.0000 1459626.0000 1517264.0000 835052.0000 1390769.0000 4259928.0000 D-glucose 1 360446.0000 496729.0000 594546.0000 858957.0000 579.0000 1534.0000 2129258.0000 1403617.0000 10439440.0000 163653.0000 120535.0000 184985.0000 541251.0000 625085.0000 489317.0000 D-glucose 2 291806.0000 299555.0000 405071.0000 538136.0000 149.0000 321400.0000 215080.0000 1396452.0000 386533.0000 250322.0000 251629.0000 159783.0000 253610.0000 645515.0000 DHAP 67.0000 122.0000 320.0000 144.0000 221.0000 356.0000 274.0000 635.0000 201.0000 187.0000 112.0000 249.0000 343.0000 Diethyl Phthalate 5669.0000 3176.0000 6166.0000 6521.0000 2375.0000 12626.0000 23954.0000 Diglycerol 186.0000 199.0000 119.0000 135.0000 225.0000 DL-3-Aminoisobutyric acid 537.0000 745.0000 953.0000 500.0000 224.0000 192.0000 327.0000 866.0000 1056.0000 743.0000 411.0000 543.0000 447.0000 768.0000 D-Malic acid 38813.0000 59230.0000 70292.0000 89266.0000 1429.0000 759.0000 32110.0000 17819.0000 17172.0000 65443.0000 44376.0000 46177.0000 135662.0000 199500.0000 131612.0000 D-Mannose 1 16323.0000 21530.0000 25257.0000 36263.0000 155.0000 28451.0000 23071.0000 43493.0000 25392.0000 21946.0000 23136.0000 657.0000 1499.0000 2627.0000 D-Mannose 2 1221.0000 1788.0000 1253.0000 1565.0000 297.0000 118.0000 253.0000 686.0000 472.0000 892.0000 989.0000 434.0000 503.0000 947.0000 D-ribose-5-phosphate 729.0000 1083.0000 1041.0000 416.0000 504.0000 577.0000 876.0000 649.0000 D-threitol 11389.0000 25455.0000 20934.0000 22948.0000 75612.0000 59789.0000 9636.0000 8270.0000 8071.0000 9833.0000 19740.0000 29227.0000 26090.0000 Eicosane 470.0000 8639.0000 20321.0000 4032.0000 12576.0000 3019.0000 514.0000 11992.0000 1404.0000 6590.0000 19577.0000 2652.0000 10064.0000 Elaidic acid 14558.0000 16583.0000 19309.0000 2595.0000 1595.0000 12545.0000 16275.0000 15453.0000 5948.0000 9413.0000 7315.0000 14517.0000 11778.0000 8978.0000 17374.0000 Ergosterol 777.0000 2378.0000 14663.0000 2415.0000 1149.0000 510.0000 6857.0000 3454.0000 1609.0000 ethanolamine 51495.0000 56740.0000 4786.0000 4264.0000 34782.0000 34964.0000 59106.0000 49485.0000 51906.0000 44117.0000 31678.0000 73004.0000 109631.0000 79678.0000 Ethanolamine 243169.0000 359104.0000 424286.0000 541668.0000 223787.0000 244198.0000 501277.0000 409177.0000 327606.0000 354497.0000 286841.0000 255962.0000 321557.0000 328258.0000 620063.0000 397003.0000 Fructose-6-phosphate 1197.0000 3161.0000 386.0000 409.0000 2297.0000 2630.0000 2062.0000 966.0000 344.0000 1685.0000 Fumaric acid 15588.0000 24853.0000 28967.0000 33031.0000 6570.0000 7028.0000 8575.0000 17857.0000 12838.0000 16592.0000 18990.0000 13332.0000 21439.0000 35432.0000 49454.0000 48695.0000 GABA 441067.0000 740396.0000 904983.0000 1008784.0000 1180.0000 661.0000 2686.0000 630330.0000 433876.0000 415565.0000 281823.0000 255053.0000 341319.0000 614829.0000 1060323.0000 1055418.0000 Galactitol 9993.0000 16289.0000 20843.0000 25343.0000 494.0000 14020.0000 16097.0000 19784.0000 7130.0000 13213.0000 19030.0000 17579.0000 Galactonic acid 952.0000 895.0000 2390.0000 214.0000 353.0000 839.0000 790.0000 712.0000 1815.0000 1502.0000 1067.0000 2899.0000 Gluconic acid 1837.0000 1740.0000 2858.0000 171.0000 1968.0000 1493.0000 1146.0000 984.0000 925.0000 579.0000 Glucose 6-phosphate 890.0000 207.0000 775.0000 91.0000 1572.0000 426.0000 1773.0000 Glutamine 231030.0000 221455.0000 168744.0000 27657.0000 643.0000 366.0000 878.0000 131145.0000 129554.0000 94218.0000 22623.0000 12107.0000 10473.0000 42632.0000 2494.0000 22271.0000 Glutaric acid 177.0000 297.0000 350.0000 170.0000 218.0000 252.0000 178.0000 140.0000 487.0000 267.0000 211.0000 181.0000 215.0000 122.0000 Glutathione 142.0000 2061.0000 277.0000 699.0000 1454.0000 Glycerol 5540762.0000 5784932.0000 7535964.0000 9228843.0000 18833.0000 51936.0000 41121.0000 8088790.0000 7864594.0000 9247029.0000 2861162.0000 3590085.0000 3801313.0000 14464339.0000 16586832.0000 15087282.0000 glycerol 3-phosphate 244.0000 2194.0000 3798.0000 4538.0000 144.0000 199.0000 857.0000 1212.0000 929.0000 925.0000 1087.0000 5178.0000 5114.0000 5459.0000 Glycine 132283.0000 234463.0000 248571.0000 305234.0000 1839.0000 2046.0000 2388.0000 187658.0000 163523.0000 149043.0000 177126.0000 131930.0000 199520.0000 546965.0000 656955.0000 596104.0000 Glycolic acid 17795.0000 20313.0000 37296.0000 29736.0000 20048.0000 24033.0000 22222.0000 Glyoxylic acid 4141.0000 184.0000 Guanine 118.0000 682.0000 609.0000 147.0000 184.0000 286.0000 546.0000 222.0000 825.0000 734.0000 267.0000 420.0000 577.0000 Heptadecanoic acid 100599.0000 589.0000 2563.0000 hexadecene 814.0000 1435.0000 935.0000 162.0000 2453.0000 2429.0000 808.0000 Histamine 2066.0000 2061.0000 3162.0000 8076.0000 76.0000 245.0000 409.0000 4426.0000 2783.0000 7753.0000 Hypotaurine 1411.0000 1685.0000 2416.0000 3143.0000 393.0000 473.0000 1880.0000 1345.0000 699.0000 861.0000 3940.0000 3076.0000 3345.0000 Hypoxanthine 54919.0000 66757.0000 82521.0000 115410.0000 610.0000 215.0000 405.0000 136592.0000 109383.0000 94506.0000 25057.0000 22709.0000 25868.0000 44761.0000 68501.0000 42811.0000 Iminodiacetic acid 4287.0000 3903.0000 4742.0000 6175.0000 4945.0000 3384.0000 7353.0000 5607.0000 6885.0000 4919.0000 6251.0000 3762.0000 5734.0000 6659.0000 8949.0000 5597.0000 Inosine 23756.0000 18215.0000 16642.0000 27302.0000 276.0000 198.0000 17239.0000 14363.0000 36425.0000 21076.0000 3069.0000 22399.0000 6702.0000 12959.0000 23768.0000 Inosine 5^-monophosphate 283.0000 1544.0000 4479.0000 1477.0000 685.0000 765.0000 Inositol phosphate 166548.0000 173375.0000 225095.0000 400965.0000 139.0000 2076.0000 2614.0000 197833.0000 126790.0000 141094.0000 214805.0000 155544.0000 198810.0000 275455.0000 325989.0000 288033.0000 Isocitric acid 1282.0000 600.0000 417.0000 476.0000 608.0000 2191.0000 2359.0000 3352.0000 1267.0000 702.0000 334.0000 239.0000 Isoxanthopterin 370.0000 285.0000 285.0000 158.0000 135.0000 214.0000 97.0000 211.0000 242.0000 278.0000 184.0000 345.0000 Kynurenic acid 162.0000 810.0000 330.0000 276.0000 L-Alanine 1 172.0000 576.0000 424.0000 642.0000 287.0000 92.0000 363.0000 395.0000 124.0000 232.0000 543.0000 L-Alanine 2 1551725.0000 2355022.0000 2591786.0000 2668829.0000 6500.0000 15147.0000 24620.0000 1330488.0000 1114273.0000 1064587.0000 268189.0000 242995.0000 304908.0000 975342.0000 1020012.0000 1378900.0000 lanthionine 5769.0000 6345.0000 8822.0000 11060.0000 10093.0000 5446.0000 25537.0000 11045.0000 6871.0000 5758.0000 3174.0000 5604.0000 14553.0000 L-Ascorbic acid 1998.0000 2200.0000 3369.0000 346.0000 216.0000 483.0000 1568.0000 1099.0000 10031.0000 2373.0000 2112.0000 4481.0000 L-Asparagine 21788.0000 28697.0000 39726.0000 31461.0000 361.0000 29178.0000 10337.0000 13822.0000 18638.0000 12443.0000 17245.0000 69112.0000 33512.0000 79041.0000 L-Aspartic acid 1 305056.0000 425686.0000 584166.0000 1106959.0000 2131.0000 3451.0000 8990.0000 378523.0000 265823.0000 267943.0000 304107.0000 192841.0000 365072.0000 423682.0000 964031.0000 458087.0000 L-Aspartic acid 2 6170249.0000 12679393.0000 14615846.0000 16627048.0000 1051.0000 3069.0000 3620.0000 7554094.0000 6923882.0000 5266443.0000 7132780.0000 4152232.0000 6817614.0000 16407868.0000 17378925.0000 16954663.0000 Lauric Acid 30582.0000 34531.0000 39267.0000 52401.0000 10098.0000 7490.0000 14389.0000 30210.0000 37171.0000 17094.0000 24345.0000 29888.0000 31450.0000 37520.0000 90295.0000 49046.0000 L-Dopa 928.0000 659.0000 738.0000 2076.0000 583.0000 L-Glutamic acid 549568.0000 1152596.0000 1329429.0000 825345.0000 147.0000 266.0000 1014725.0000 840816.0000 600320.0000 597617.0000 364018.0000 539952.0000 1641660.0000 743843.0000 1607103.0000 L-gulonic acid gamma-lactone 540.0000 192.0000 343.0000 177.0000 92.0000 208.0000 288.0000 372.0000 379.0000 764.0000 Linoleic acid 134.0000 792.0000 728.0000 143.0000 605.0000 1581.0000 906.0000 752.0000 922.0000 756.0000 513.0000 L-Isoleucine 1 181267.0000 168817.0000 201563.0000 346505.0000 247690.0000 235681.0000 697721.0000 191428.0000 177061.0000 199753.0000 208337.0000 163445.0000 172085.0000 201876.0000 474592.0000 237179.0000 L-Isoleucine 2 154065.0000 187716.0000 244379.0000 224659.0000 81655.0000 88936.0000 64360.0000 38513.0000 37867.0000 39800.0000 309434.0000 413052.0000 446270.0000 L-Kynurenine 898.0000 693.0000 361.0000 2047.0000 215.0000 679.0000 L-Lactic acid 123022.0000 94941.0000 119431.0000 126269.0000 45097.0000 33345.0000 61217.0000 138633.0000 151484.0000 106824.0000 76155.0000 74195.0000 89769.0000 161060.0000 288149.0000 219484.0000 L-Leucine 1 18835.0000 29922.0000 36827.0000 80978.0000 357.0000 1384.0000 13323.0000 11825.0000 8899.0000 16743.0000 13954.0000 17940.0000 33772.0000 76011.0000 45565.0000 L-Leucine 2 213607.0000 301801.0000 352820.0000 290762.0000 195.0000 103673.0000 113372.0000 70367.0000 183653.0000 164309.0000 182715.0000 407303.0000 509199.0000 600182.0000 L-Lysine 1 479.0000 338.0000 567.0000 233.0000 879.0000 373.0000 121.0000 358.0000 269.0000 L-Lysine 2 5458260.0000 7743873.0000 9082883.0000 12942761.0000 433.0000 3096.0000 7287.0000 581437.0000 480523.0000 402204.0000 2823400.0000 2102669.0000 3066927.0000 8321794.0000 9596539.0000 7943755.0000 L-Methionine 1 3185.0000 1459.0000 525.0000 530.0000 2270.0000 977.0000 L-Methionine 2 98570.0000 158121.0000 182261.0000 188615.0000 1230.0000 1072.0000 740.0000 113354.0000 194463.0000 98954.0000 76797.0000 83353.0000 61918.0000 318047.0000 432244.0000 420388.0000 L-Phenylalanine 1 93624.0000 115415.0000 156091.0000 290483.0000 626.0000 1780.0000 44265.0000 39066.0000 31405.0000 19440.0000 21901.0000 25795.0000 135394.0000 398867.0000 184461.0000 L-Phenylalanine 2 89742.0000 136190.0000 158543.0000 170947.0000 777.0000 42006.0000 46273.0000 27930.0000 19080.0000 18085.0000 20623.0000 209071.0000 252962.0000 273764.0000 L-Proline 1 7152.0000 10713.0000 14201.0000 32354.0000 978.0000 3887.0000 15753.0000 10546.0000 11556.0000 4934.0000 2808.0000 4633.0000 21508.0000 28176.0000 26616.0000 L-Proline 2 59076.0000 93012.0000 110260.0000 88992.0000 709.0000 91796.0000 82244.0000 78351.0000 61560.0000 51743.0000 58571.0000 179031.0000 171161.0000 238001.0000 L-Serine 1 10654.0000 18013.0000 27472.0000 41741.0000 39017.0000 26964.0000 25813.0000 19338.0000 10027.0000 24726.0000 57805.0000 88544.0000 51383.0000 L-Serine 2 622707.0000 967425.0000 1203115.0000 1166457.0000 7253.0000 3792.0000 3207.0000 1437068.0000 1332213.0000 972122.0000 982534.0000 714641.0000 913457.0000 3846233.0000 3990515.0000 4583225.0000 L-Sorbose 7430.0000 11047.0000 14020.0000 19825.0000 164.0000 145.0000 174.0000 19976.0000 7136.0000 9894.0000 11690.0000 7050.0000 15353.0000 11111.0000 16391.0000 27860.0000 L-threonine 186938.0000 331476.0000 383254.0000 612524.0000 38777.0000 16961.0000 18039.0000 452144.0000 315904.0000 255932.0000 153280.0000 110408.0000 212469.0000 550334.0000 857459.0000 570512.0000 L-Threonine 336388.0000 501025.0000 619991.0000 627188.0000 418.0000 1253.0000 659336.0000 638241.0000 439769.0000 406184.0000 282538.0000 383059.0000 1273108.0000 1431776.0000 1470099.0000 L-Tryptophan 11400.0000 13775.0000 17243.0000 43002.0000 5723.0000 3834.0000 14102.0000 16750.0000 7976.0000 7985.0000 7586.0000 7551.0000 8368.0000 21685.0000 28760.0000 13219.0000 L-Tyrosine 1 7225.0000 14355.0000 18850.0000 20556.0000 2248.0000 2527.0000 2844.0000 3871.0000 5089.0000 16750.0000 7841.0000 L-Tyrosine 2 161922.0000 223728.0000 265445.0000 401567.0000 341.0000 213.0000 1896.0000 15838.0000 16570.0000 16995.0000 32982.0000 27228.0000 33840.0000 90283.0000 127767.0000 120023.0000 L-Valine 1 226629.0000 329643.0000 277737.0000 492595.0000 1317.0000 447506.0000 383184.0000 253025.0000 85010.0000 63273.0000 92493.0000 306583.0000 442530.0000 425714.0000 L-Valine 2 763851.0000 965100.0000 1285170.0000 1458961.0000 1514.0000 1171.0000 4363.0000 922117.0000 870653.0000 601445.0000 251122.0000 214151.0000 246674.0000 1343365.0000 1794486.0000 1826710.0000 Malonic acid 574.0000 707.0000 1002.0000 270.0000 1106.0000 588.0000 500.0000 652.0000 672.0000 481.0000 617.0000 methyl-beta-D-galactopyranoside 32106.0000 1863.0000 46.0000 24791.0000 20329.0000 21652.0000 10727.0000 6694.0000 10466.0000 22208.0000 3514.0000 Myoinositol 295117.0000 420298.0000 474483.0000 682776.0000 121.0000 610.0000 148.0000 515375.0000 416091.0000 424246.0000 510831.0000 374448.0000 532731.0000 408219.0000 568305.0000 492346.0000 Myristic acid 481434.0000 618485.0000 645253.0000 896190.0000 391123.0000 340965.0000 797919.0000 559436.0000 394126.0000 352513.0000 373424.0000 291356.0000 341587.0000 700587.0000 1258100.0000 599734.0000 Myristic Acid d27 192.0000 300.0000 768.0000 5060.0000 894.0000 808.0000 N-acetyl-L-aspartic acid 1 1799.0000 591.0000 2079.0000 2429.0000 2699.0000 1605.0000 1721.0000 5522.0000 N-acetyl-L-aspartic acid 2 465.0000 806.0000 357.0000 154.0000 199.0000 146.0000 512.0000 187.0000 125.0000 200.0000 89.0000 691.0000 Nicotinamide 112548.0000 135394.0000 159994.0000 235176.0000 1174.0000 1753.0000 127055.0000 132317.0000 113791.0000 102220.0000 119751.0000 97721.0000 167057.0000 348237.0000 169251.0000 Nitrous Oxide 440199.0000 430661.0000 417892.0000 421092.0000 437272.0000 328356.0000 223220.0000 376762.0000 352392.0000 373349.0000 390344.0000 339448.0000 367500.0000 487386.0000 609027.0000 366190.0000 N-methylalanine 4811.0000 19308.0000 4480.0000 4056.0000 6879.0000 14640.0000 5620.0000 11805.0000 10929.0000 14933.0000 8287.0000 4846.0000 5382.0000 9133.0000 5984.0000 10907.0000 nonanoic acid 207374.0000 204547.0000 248481.0000 308350.0000 148310.0000 181269.0000 296831.0000 235303.0000 200885.0000 206684.0000 165626.0000 172104.0000 186240.0000 229472.0000 532341.0000 209953.0000 Oleic acid 26396.0000 9357.0000 35239.0000 23279.0000 6560.0000 40332.0000 48107.0000 69304.0000 35843.0000 53883.0000 23730.0000 53137.0000 5823.0000 10148.0000 87554.0000 67599.0000 O-Phosphoethanolamine 295.0000 753.0000 302.0000 1484.0000 687.0000 123.0000 549.0000 712.0000 211.0000 765.0000 403.0000 532.0000 454.0000 632.0000 Ornithine 779942.0000 999970.0000 1176297.0000 1413765.0000 949.0000 3559.0000 538456.0000 495926.0000 392681.0000 103864.0000 89207.0000 113953.0000 403503.0000 445095.0000 390223.0000 Oxalic acid 20373.0000 35884.0000 34948.0000 36186.0000 24958.0000 41329.0000 55968.0000 47544.0000 39264.0000 38135.0000 24950.0000 22632.0000 31370.0000 27576.0000 46480.0000 32805.0000 Palmitic acid 12794470.0000 13817801.0000 13742224.0000 17450002.0000 4610022.0000 3971181.0000 9818386.0000 13266117.0000 11751144.0000 11005479.0000 13937672.0000 10100699.0000 12050721.0000 13719873.0000 18149076.0000 13940063.0000 Palmitoleic acid 25490.0000 147944.0000 165278.0000 271177.0000 32944.0000 82557.0000 161030.0000 171693.0000 69313.0000 145309.0000 100438.0000 136465.0000 66789.0000 109943.0000 251754.0000 80835.0000 Pantothenic acid 206.0000 493.0000 580.0000 197.0000 1001.0000 89.0000 357.0000 120.0000 196.0000 Pectin 3768.0000 4618.0000 7459.0000 8918.0000 699.0000 218.0000 7836.0000 3481.0000 9560.0000 7048.0000 7531.0000 8442.0000 2282.0000 6344.0000 7013.0000 Phosphate 12324853.0000 18042923.0000 19189140.0000 21850193.0000 118054.0000 121256.0000 255950.0000 19986755.0000 19980637.0000 19259543.0000 16481745.0000 15065572.0000 18678524.0000 20945319.0000 24681547.0000 22483864.0000 Phosphatidyl Glycerol 625.0000 364.0000 131.0000 1626.0000 330.0000 589.0000 Phosphoenolpyruvate 325.0000 66.0000 457.0000 428.0000 809.0000 218.0000 picolonic acid 379.0000 310.0000 277.0000 1351.0000 831.0000 504.0000 Putrescine 773.0000 799.0000 594.0000 860.0000 1154.0000 Pyroglutamic acid 2337729.0000 4974602.0000 6352141.0000 10873160.0000 1509.0000 3479.0000 7996.0000 4458896.0000 3289071.0000 2929395.0000 1258104.0000 864217.0000 1439647.0000 2612560.0000 7021752.0000 2882643.0000 Pyrophosphate 150.0000 288.0000 234.0000 348.0000 299.0000 Pyrrolidonecarboxylic acid 11469.0000 15138.0000 17283.0000 36751.0000 947.0000 17223.0000 11597.0000 6307.0000 7275.0000 8342.0000 9244.0000 26445.0000 15719.0000 Pyruvic acid 7237.0000 10126.0000 14082.0000 18300.0000 2650.0000 12243.0000 8139.0000 9524.0000 6496.0000 7122.0000 8462.0000 9986.0000 18566.0000 16366.0000 Ribitol 1885.0000 908.0000 2535.0000 4140.0000 284.0000 2061.0000 2953.0000 2686.0000 174.0000 672.0000 1267.0000 1706.0000 4807.0000 3508.0000 ribonic acid-gamma-lactone 738.0000 1130.0000 1207.0000 1356.0000 1529.0000 1106.0000 1230.0000 1568.0000 969.0000 1312.0000 1430.0000 1870.0000 Sarcosine 13062.0000 20203.0000 20177.0000 9988.0000 21232.0000 13542.0000 10128.0000 21716.0000 18819.0000 24728.0000 14957.0000 13810.0000 17237.0000 4104.0000 5335.0000 21448.0000 Sedoheptulose 7-phosphate 1806.0000 1096.0000 1763.0000 965.0000 160.0000 5548.0000 4354.0000 1586.0000 2520.0000 3064.0000 3665.0000 289.0000 1945.0000 Serotonin 1 1098.0000 2149.0000 405.0000 364.0000 47.0000 384.0000 1789.0000 2212.0000 989.0000 3414.0000 3709.0000 Serotonin 2 925.0000 375.0000 247.0000 489.0000 sophorose 648.0000 842.0000 1135.0000 Sorbitol 112005.0000 147978.0000 175648.0000 242291.0000 118.0000 723.0000 851.0000 183668.0000 114995.0000 145908.0000 51434.0000 26531.0000 34422.0000 45401.0000 62749.0000 55263.0000 Spermidine 722.0000 383.0000 243.0000 2017.0000 1472.0000 789.0000 Stearic acid 10239324.0000 11375283.0000 12241435.0000 16020709.0000 7449868.0000 6361277.0000 14004966.0000 12131087.0000 6781391.0000 6431397.0000 12389713.0000 6701385.0000 8447487.0000 13029447.0000 15567814.0000 11033773.0000 Succinic acid 77141.0000 123955.0000 150668.0000 187404.0000 2709.0000 5338.0000 5231.0000 183204.0000 147515.0000 152499.0000 169978.0000 145131.0000 164637.0000 308665.0000 440269.0000 385296.0000 Tartaric Acid 4200.0000 8563.0000 9342.0000 10661.0000 346.0000 355.0000 10364.0000 8428.0000 4594.0000 2438.0000 1529.0000 2794.0000 5822.0000 5180.0000 8066.0000 Taurine 620.0000 2639.0000 619.0000 888.0000 1284.0000 613.0000 465.0000 2225.0000 1881.0000 840.0000 1360.0000 792.0000 1572.0000 1598.0000 1249.0000 2743.0000 threonic acid 27211.0000 80451.0000 92760.0000 127257.0000 148.0000 1137.0000 132843.0000 28548.0000 20957.0000 85855.0000 30365.0000 117822.0000 97021.0000 116529.0000 168923.0000 threose 298.0000 170.0000 217.0000 83.0000 146.0000 655.0000 282.0000 1040.0000 Thymine 1527.0000 1219.0000 327.0000 turanose 365.0000 248.0000 Uracil 173483.0000 227589.0000 272652.0000 324337.0000 23628.0000 6835.0000 8266.0000 168701.0000 187792.0000 168763.0000 204456.0000 176304.0000 201660.0000 289650.0000 508230.0000 317734.0000 Urea 46512.0000 54789.0000 66184.0000 59188.0000 34832.0000 34859.0000 34817.0000 68096.0000 57582.0000 59456.0000 32786.0000 35954.0000 38568.0000 78829.0000 127749.0000 83112.0000 Uric acid 1 383.0000 227.0000 135.0000 133.0000 164.0000 406.0000 574.0000 141.0000 145.0000 537.0000 1108.0000 Uric acid 2 461.0000 109.0000 793.0000 78.0000 1254.0000 796.0000 160.0000 uridine 4679.0000 19414.0000 22555.0000 37656.0000 224.0000 216.0000 8730.0000 11527.0000 13450.0000 3882.0000 5258.0000 683.0000 9280.0000 20998.0000 13980.0000 Uridine 5^-monophosphate 10691.0000 4722.0000 13823.0000 1128.0000 167.0000 513.0000 4232.0000 2184.0000 1804.0000 3327.0000 2305.0000 2590.0000 7109.0000 9019.0000 Xanthine 5585.0000 7671.0000 9943.0000 14335.0000 659.0000 276.0000 396.0000 4469.0000 5136.0000 5411.0000 1422.0000 1389.0000 7715.0000 10124.0000 9947.0000 Xanthurenic acid 152.0000 505.0000 120.0000 264.0000 189.0000 286.0000 915.0000 797.0000 557.0000 xylose 3415.0000 4761.0000 6973.0000 4623.0000 1898.0000 155.0000 2397.0000 815.0000 6280.0000 4434.0000 10157.0000 MS_METABOLITE_DATA_END #METABOLITES METABOLITES_START metabolite_name pubchem_id inchi_key kegg_id other_id other_id_type ri ri_type moverz_quant 1,6-anhydro-glucose 1-monomyristin 1-octadecene 1-Palmitoylglycerol 1-Steroylglycerol 2'3'-Bisphosphoglycerate 2-Hydroxybenzoic acid 2-Hydroxybutyric acid 2 2-Hydroxyglutaric acid 1 2-ketoglutarate 2-Ketoisocaproic acid 2-monopalmitoylglycerol 2-Steroylglycerol 3-hydroxybutyric acid 3-Phosphoglyceric acid 4-Hydroxyproline 1 4-Hydroxyproline 2 5-hydroxytryptophan Adenine Adenosine Adenosine monophosphate Adipic acid Allantoin alpha-D-glucosamine 1-phosphate Aminoadipic acid Arachidic acid Arachidonic Acid azelaic acid Benzoic acid Benzoquinone Beta-Alanine Beta-Glycerophosphoric acid Beta-lactate Beta-Sitosterol Capric acid Cellobiose Cholesterol cis-Aconitic acid Citric acid Creatinine Cystathionine d4-succinate Dehydroascorbic acid delta Amino Levulinic acid D-Fructose 1 D-Fructose 2 D-Galactose D-glucose 1 D-glucose 2 DHAP Diethyl Phthalate Diglycerol DL-3-Aminoisobutyric acid D-Malic acid D-Mannose 1 D-Mannose 2 D-ribose-5-phosphate D-threitol Eicosane Elaidic acid Ergosterol ethanolamine Ethanolamine Fructose-6-phosphate Fumaric acid GABA Galactitol Galactonic acid Gluconic acid Glucose 6-phosphate Glutamine Glutaric acid Glutathione Glycerol glycerol 3-phosphate Glycine Glycolic acid Glyoxylic acid Guanine Heptadecanoic acid hexadecene Histamine Hypotaurine Hypoxanthine Iminodiacetic acid Inosine Inosine 5'-monophosphate Inositol phosphate Isocitric acid Isoxanthopterin Kynurenic acid L-Alanine 1 L-Alanine 2 lanthionine L-Ascorbic acid L-Asparagine L-Aspartic acid 1 L-Aspartic acid 2 Lauric Acid L-Dopa L-Glutamic acid L-gulonic acid gamma-lactone Linoleic acid L-Isoleucine 1 L-Isoleucine 2 L-Kynurenine L-Lactic acid L-Leucine 1 L-Leucine 2 L-Lysine 1 L-Lysine 2 L-Methionine 1 L-Methionine 2 L-Phenylalanine 1 L-Phenylalanine 2 L-Proline 1 L-Proline 2 L-Serine 1 L-Serine 2 L-Sorbose L-threonine L-Threonine L-Tryptophan L-Tyrosine 1 L-Tyrosine 2 L-Valine 1 L-Valine 2 Malonic acid methyl-beta-D-galactopyranoside Myoinositol Myristic acid Myristic Acid d27 N-acetyl-L-aspartic acid 1 N-acetyl-L-aspartic acid 2 Nicotinamide Nitrous Oxide N-methylalanine nonanoic acid Oleic acid O-Phosphoethanolamine Ornithine Oxalic acid Palmitic acid Palmitoleic acid Pantothenic acid Pectin Phosphate Phosphatidyl Glycerol Phosphoenolpyruvate picolonic acid Putrescine Pyroglutamic acid Pyrophosphate Pyrrolidonecarboxylic acid Pyruvic acid Ribitol ribonic acid-gamma-lactone Sarcosine Sedoheptulose 7-phosphate Serotonin 1 Serotonin 2 sophorose Sorbitol Spermidine Stearic acid Succinic acid Tartaric Acid Taurine threonic acid threose Thymine turanose Uracil Urea Uric acid 1 Uric acid 2 uridine Uridine 5'-monophosphate Xanthine Xanthurenic acid xylose METABOLITES_END #END