#METABOLOMICS WORKBENCH cwwong_20220511_144441 DATATRACK_ID:3242 STUDY_ID:ST002161 ANALYSIS_ID:AN003540 PROJECT_ID:PR001374 VERSION 1 CREATED_ON May 12, 2022, 8:30 am #PROJECT PR:PROJECT_TITLE Glycerate Production from Intestinal Fructose Metabolism Elevated by Dietary Fat PR:PROJECT_TITLE Induces Glucose Intolerance Through β-cell Damage PR:PROJECT_SUMMARY Dietary fructose, especially in the context of a high-fat western diet, has been PR:PROJECT_SUMMARY linked to type 2 diabetes. Although the effect of fructose on liver metabolism PR:PROJECT_SUMMARY has been extensively studied, a significant portion of the fructose is first PR:PROJECT_SUMMARY metabolized in the small intestine. Here we report that dietary fat enhances PR:PROJECT_SUMMARY intestinal fructose metabolism, which releases glycerate into the blood. High PR:PROJECT_SUMMARY systemic glycerate levels reduce pancreatic islet sizes and β-cell content, PR:PROJECT_SUMMARY thus inducing glucose intolerance. Our findings provide an additional link PR:PROJECT_SUMMARY between dietary fructose and diabetes that is modulated by dietary fat. PR:INSTITUTE Duke University PR:LAST_NAME Wong PR:FIRST_NAME Chi Wut PR:ADDRESS CEIMAS, 101 Science Dr. Room 2141, Durham, NC, 27709, USA PR:EMAIL chiwut.wong@duke.edu PR:PHONE 9495290320 #STUDY ST:STUDY_TITLE Glycerate Production from Intestinal Fructose Metabolism Elevated by Dietary Fat ST:STUDY_TITLE Induces Glucose Intolerance Through β-cell Damage ST:STUDY_SUMMARY Dietary fructose, especially in the context of a high-fat western diet, has been ST:STUDY_SUMMARY linked to type 2 diabetes. Although the effect of fructose on liver metabolism ST:STUDY_SUMMARY has been extensively studied, a significant portion of the fructose is first ST:STUDY_SUMMARY metabolized in the small intestine. Here we report that dietary fat enhances ST:STUDY_SUMMARY intestinal fructose metabolism, which releases glycerate into the blood. High ST:STUDY_SUMMARY systemic glycerate levels reduce pancreatic islet sizes and β-cell content, ST:STUDY_SUMMARY thus inducing glucose intolerance. Our findings provide an additional link ST:STUDY_SUMMARY between dietary fructose and diabetes that is modulated by dietary fat. ST:INSTITUTE Duke University ST:LAST_NAME Wong ST:FIRST_NAME Chi Wut ST:ADDRESS CEIMAS, 101 Science Dr. Room 2141, Durham, NC, 27709, USA ST:EMAIL chiwut.wong@duke.edu ST:PHONE 9495290320 #SUBJECT SU:SUBJECT_TYPE Mammal SU:SUBJECT_SPECIES Mus musculus SU:TAXONOMY_ID 10090 #SUBJECT_SAMPLE_FACTORS: SUBJECT(optional)[tab]SAMPLE[tab]FACTORS(NAME:VALUE pairs separated by |)[tab]Raw file names and additional sample data SUBJECT_SAMPLE_FACTORS 13163 13C-Fruc_HFD-HV_13163 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Batch=6; Experiment=LC-MS; RAW_FILE_NAME=13C-Fruc_HFD-HV_13163.mzXML SUBJECT_SAMPLE_FACTORS 13164 13C-Fruc_HFD-HV_13164 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Batch=6; Experiment=LC-MS; RAW_FILE_NAME=13C-Fruc_HFD-HV_13164.mzXML SUBJECT_SAMPLE_FACTORS 13165 13C-Fruc_HFD-HV_13165 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Batch=6; Experiment=LC-MS; RAW_FILE_NAME=13C-Fruc_HFD-HV_13165.mzXML SUBJECT_SAMPLE_FACTORS 13166 13C-Fruc_HFD-HV_13166 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Batch=6; Experiment=LC-MS; RAW_FILE_NAME=13C-Fruc_HFD-HV_13166.mzXML SUBJECT_SAMPLE_FACTORS 13167 13C-Fruc_HFD-HV_13167 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Batch=6; Experiment=LC-MS; RAW_FILE_NAME=13C-Fruc_HFD-HV_13167.mzXML SUBJECT_SAMPLE_FACTORS 13163 13C-Fruc_HFD-PV_13163 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):10 | Drinking:Water Batch=6; Experiment=LC-MS; RAW_FILE_NAME=13C-Fruc_HFD-PV_13163.mzXML SUBJECT_SAMPLE_FACTORS 13164 13C-Fruc_HFD-PV_13164 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):10 | Drinking:Water Batch=6; Experiment=LC-MS; RAW_FILE_NAME=13C-Fruc_HFD-PV_13164.mzXML SUBJECT_SAMPLE_FACTORS 13165 13C-Fruc_HFD-PV_13165 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):10 | Drinking:Water Batch=6; Experiment=LC-MS; RAW_FILE_NAME=13C-Fruc_HFD-PV_13165.mzXML SUBJECT_SAMPLE_FACTORS 13166 13C-Fruc_HFD-PV_13166 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):10 | Drinking:Water Batch=6; Experiment=LC-MS; RAW_FILE_NAME=13C-Fruc_HFD-PV_13166.mzXML SUBJECT_SAMPLE_FACTORS 13167 13C-Fruc_HFD-PV_13167 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):10 | Drinking:Water Batch=6; Experiment=LC-MS; RAW_FILE_NAME=13C-Fruc_HFD-PV_13167.mzXML SUBJECT_SAMPLE_FACTORS 13168 13C-Fruc_LFD-HV_13168 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Batch=6; Experiment=LC-MS; RAW_FILE_NAME=13C-Fruc_LFD-HV_13168.mzXML SUBJECT_SAMPLE_FACTORS 13169 13C-Fruc_LFD-HV_13169 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Batch=6; Experiment=LC-MS; RAW_FILE_NAME=13C-Fruc_LFD-HV_13169.mzXML SUBJECT_SAMPLE_FACTORS 13170 13C-Fruc_LFD-HV_13170 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Batch=6; Experiment=LC-MS; RAW_FILE_NAME=13C-Fruc_LFD-HV_13170.mzXML SUBJECT_SAMPLE_FACTORS 13171 13C-Fruc_LFD-HV_13171 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Batch=6; Experiment=LC-MS; RAW_FILE_NAME=13C-Fruc_LFD-HV_13171.mzXML SUBJECT_SAMPLE_FACTORS 13172 13C-Fruc_LFD-HV_13172 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Batch=6; Experiment=LC-MS; RAW_FILE_NAME=13C-Fruc_LFD-HV_13172.mzXML SUBJECT_SAMPLE_FACTORS 13168 13C-Fruc_LFD-PV_13168 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):10 | Drinking:Water Batch=6; Experiment=LC-MS; RAW_FILE_NAME=13C-Fruc_LFD-PV_13168.mzXML SUBJECT_SAMPLE_FACTORS 13169 13C-Fruc_LFD-PV_13169 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):10 | Drinking:Water Batch=6; Experiment=LC-MS; RAW_FILE_NAME=13C-Fruc_LFD-PV_13169.mzXML SUBJECT_SAMPLE_FACTORS 13170 13C-Fruc_LFD-PV_13170 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):10 | Drinking:Water Batch=6; Experiment=LC-MS; RAW_FILE_NAME=13C-Fruc_LFD-PV_13170.mzXML SUBJECT_SAMPLE_FACTORS 13171 13C-Fruc_LFD-PV_13171 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):10 | Drinking:Water Batch=6; Experiment=LC-MS; RAW_FILE_NAME=13C-Fruc_LFD-PV_13171.mzXML SUBJECT_SAMPLE_FACTORS 13172 13C-Fruc_LFD-PV_13172 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):10 | Drinking:Water Batch=6; Experiment=LC-MS; RAW_FILE_NAME=13C-Fruc_LFD-PV_13172.mzXML SUBJECT_SAMPLE_FACTORS Blank_batch1 Blank_batch1 Genotype:Blank | Diet:Blank | Diet Duration:Blank | Treatment:Blank | Tissue:Blank | Collection Time (minute):Blank | Drinking:Blank Batch=1; Experiment=LC-MS; RAW_FILE_NAME=Blank_batch1.mzXML SUBJECT_SAMPLE_FACTORS Blank_batch10 Blank_batch10 Genotype:Blank | Diet:Blank | Diet Duration:Blank | Treatment:Blank | Tissue:Blank | Collection Time (minute):Blank | Drinking:Blank Batch=10; Experiment=LC-MS; RAW_FILE_NAME=Blank_batch10.mzXML SUBJECT_SAMPLE_FACTORS Blank_batch11 Blank_batch11 Genotype:Blank | Diet:Blank | Diet Duration:Blank | Treatment:Blank | Tissue:Blank | Collection Time (minute):Blank | Drinking:Blank Batch=11; Experiment=LC-MS; RAW_FILE_NAME=Blank_batch11.mzXML SUBJECT_SAMPLE_FACTORS Blank_batch2 Blank_batch2 Genotype:Blank | Diet:Blank | Diet Duration:Blank | Treatment:Blank | Tissue:Blank | Collection Time (minute):Blank | Drinking:Blank Batch=2; Experiment=LC-MS; RAW_FILE_NAME=Blank_batch2.mzXML SUBJECT_SAMPLE_FACTORS Blank_batch3 Blank_batch3 Genotype:Blank | Diet:Blank | Diet Duration:Blank | Treatment:Blank | Tissue:Blank | Collection Time (minute):Blank | Drinking:Blank Batch=3; Experiment=LC-MS; RAW_FILE_NAME=Blank_batch3.mzXML SUBJECT_SAMPLE_FACTORS Blank_batch4 Blank_batch4 Genotype:Blank | Diet:Blank | Diet Duration:Blank | Treatment:Blank | Tissue:Blank | Collection Time (minute):Blank | Drinking:Blank Batch=4; Experiment=LC-MS; RAW_FILE_NAME=Blank_batch4.mzXML SUBJECT_SAMPLE_FACTORS Blank_batch5 Blank_batch5 Genotype:Blank | Diet:Blank | Diet Duration:Blank | Treatment:Blank | Tissue:Blank | Collection Time (minute):Blank | Drinking:Blank Batch=5; Experiment=LC-MS; RAW_FILE_NAME=Blank_batch5.mzXML SUBJECT_SAMPLE_FACTORS Blank_batch6 Blank_batch6 Genotype:Blank | Diet:Blank | Diet Duration:Blank | Treatment:Blank | Tissue:Blank | Collection Time (minute):Blank | Drinking:Blank Batch=6; Experiment=LC-MS; RAW_FILE_NAME=Blank_batch6.mzXML SUBJECT_SAMPLE_FACTORS Blank_batch7 Blank_batch7 Genotype:Blank | Diet:Blank | Diet Duration:Blank | Treatment:Blank | Tissue:Blank | Collection Time (minute):Blank | Drinking:Blank Batch=7; Experiment=LC-MS; RAW_FILE_NAME=Blank_batch7.mzXML SUBJECT_SAMPLE_FACTORS Blank_batch8 Blank_batch8 Genotype:Blank | Diet:Blank | Diet Duration:Blank | Treatment:Blank | Tissue:Blank | Collection Time (minute):Blank | Drinking:Blank Batch=8; Experiment=LC-MS; RAW_FILE_NAME=Blank_batch8.mzXML SUBJECT_SAMPLE_FACTORS Blank_batch9 Blank_batch9 Genotype:Blank | Diet:Blank | Diet Duration:Blank | Treatment:Blank | Tissue:Blank | Collection Time (minute):Blank | Drinking:Blank Batch=9; Experiment=LC-MS; RAW_FILE_NAME=Blank_batch9.mzXML SUBJECT_SAMPLE_FACTORS 13156 CON-HV_0_13156 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Water Batch=5; Experiment=LC-MS; RAW_FILE_NAME=CON-HV_0_13156.mzXML SUBJECT_SAMPLE_FACTORS 13157 CON-HV_0_13157 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Water Batch=5; Experiment=LC-MS; RAW_FILE_NAME=CON-HV_0_13157.mzXML SUBJECT_SAMPLE_FACTORS 13158 CON-HV_0_13158 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Water Batch=5; Experiment=LC-MS; RAW_FILE_NAME=CON-HV_0_13158.mzXML SUBJECT_SAMPLE_FACTORS 12156 CON-HV_120_12156 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):120 | Drinking:Water Batch=5; Experiment=LC-MS; RAW_FILE_NAME=CON-HV_120_12156.mzXML SUBJECT_SAMPLE_FACTORS 12157 CON-HV_120_12157 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):120 | Drinking:Water Batch=5; Experiment=LC-MS; RAW_FILE_NAME=CON-HV_120_12157.mzXML SUBJECT_SAMPLE_FACTORS 12158 CON-HV_120_12158 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):120 | Drinking:Water Batch=5; Experiment=LC-MS; RAW_FILE_NAME=CON-HV_120_12158.mzXML SUBJECT_SAMPLE_FACTORS 12106 CON-HV_15_12106 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):15 | Drinking:Water Batch=4; Experiment=LC-MS; RAW_FILE_NAME=CON-HV_15_12106.mzXML SUBJECT_SAMPLE_FACTORS 12107 CON-HV_15_12107 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):15 | Drinking:Water Batch=4; Experiment=LC-MS; RAW_FILE_NAME=CON-HV_15_12107.mzXML SUBJECT_SAMPLE_FACTORS 12108 CON-HV_15_12108 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):15 | Drinking:Water Batch=4; Experiment=LC-MS; RAW_FILE_NAME=CON-HV_15_12108.mzXML SUBJECT_SAMPLE_FACTORS 12109 CON-HV_15_12109 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):15 | Drinking:Water Batch=4; Experiment=LC-MS; RAW_FILE_NAME=CON-HV_15_12109.mzXML SUBJECT_SAMPLE_FACTORS 12110 CON-HV_15_12110 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):15 | Drinking:Water Batch=4; Experiment=LC-MS; RAW_FILE_NAME=CON-HV_15_12110.mzXML SUBJECT_SAMPLE_FACTORS 12116 CON-HV_30_12116 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):30 | Drinking:Water Batch=4; Experiment=LC-MS; RAW_FILE_NAME=CON-HV_30_12116.mzXML SUBJECT_SAMPLE_FACTORS 12117 CON-HV_30_12117 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):30 | Drinking:Water Batch=4; Experiment=LC-MS; RAW_FILE_NAME=CON-HV_30_12117.mzXML SUBJECT_SAMPLE_FACTORS 12118 CON-HV_30_12118 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):30 | Drinking:Water Batch=4; Experiment=LC-MS; RAW_FILE_NAME=CON-HV_30_12118.mzXML SUBJECT_SAMPLE_FACTORS 12119 CON-HV_30_12119 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):30 | Drinking:Water Batch=4; Experiment=LC-MS; RAW_FILE_NAME=CON-HV_30_12119.mzXML SUBJECT_SAMPLE_FACTORS 12120 CON-HV_30_12120 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):30 | Drinking:Water Batch=4; Experiment=LC-MS; RAW_FILE_NAME=CON-HV_30_12120.mzXML SUBJECT_SAMPLE_FACTORS 12126 CON-HV_45_12126 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):45 | Drinking:Water Batch=3; Experiment=LC-MS; RAW_FILE_NAME=CON-HV_45_12126.mzXML SUBJECT_SAMPLE_FACTORS 12127 CON-HV_45_12127 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):45 | Drinking:Water Batch=3; Experiment=LC-MS; RAW_FILE_NAME=CON-HV_45_12127.mzXML SUBJECT_SAMPLE_FACTORS 12128 CON-HV_45_12128 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):45 | Drinking:Water Batch=3; Experiment=LC-MS; RAW_FILE_NAME=CON-HV_45_12128.mzXML SUBJECT_SAMPLE_FACTORS 12129 CON-HV_45_12129 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):45 | Drinking:Water Batch=3; Experiment=LC-MS; RAW_FILE_NAME=CON-HV_45_12129.mzXML SUBJECT_SAMPLE_FACTORS 12130 CON-HV_45_12130 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):45 | Drinking:Water Batch=3; Experiment=LC-MS; RAW_FILE_NAME=CON-HV_45_12130.mzXML SUBJECT_SAMPLE_FACTORS 12136 CON-HV_60_12136 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):60 | Drinking:Water Batch=3; Experiment=LC-MS; RAW_FILE_NAME=CON-HV_60_12136.mzXML SUBJECT_SAMPLE_FACTORS 12137 CON-HV_60_12137 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):60 | Drinking:Water Batch=3; Experiment=LC-MS; RAW_FILE_NAME=CON-HV_60_12137.mzXML SUBJECT_SAMPLE_FACTORS 12138 CON-HV_60_12138 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):60 | Drinking:Water Batch=3; Experiment=LC-MS; RAW_FILE_NAME=CON-HV_60_12138.mzXML SUBJECT_SAMPLE_FACTORS 12139 CON-HV_60_12139 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):60 | Drinking:Water Batch=3; Experiment=LC-MS; RAW_FILE_NAME=CON-HV_60_12139.mzXML SUBJECT_SAMPLE_FACTORS 12140 CON-HV_60_12140 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):60 | Drinking:Water Batch=3; Experiment=LC-MS; RAW_FILE_NAME=CON-HV_60_12140.mzXML SUBJECT_SAMPLE_FACTORS 12146 CON-HV_90_12146 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):90 | Drinking:Water Batch=5; Experiment=LC-MS; RAW_FILE_NAME=CON-HV_90_12146.mzXML SUBJECT_SAMPLE_FACTORS 12147 CON-HV_90_12147 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):90 | Drinking:Water Batch=5; Experiment=LC-MS; RAW_FILE_NAME=CON-HV_90_12147.mzXML SUBJECT_SAMPLE_FACTORS 12148 CON-HV_90_12148 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):90 | Drinking:Water Batch=5; Experiment=LC-MS; RAW_FILE_NAME=CON-HV_90_12148.mzXML SUBJECT_SAMPLE_FACTORS 13156 CON-PV_0_13156 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):- | Drinking:Water Batch=5; Experiment=LC-MS; RAW_FILE_NAME=CON-PV_0_13156.mzXML SUBJECT_SAMPLE_FACTORS 13157 CON-PV_0_13157 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):- | Drinking:Water Batch=5; Experiment=LC-MS; RAW_FILE_NAME=CON-PV_0_13157.mzXML SUBJECT_SAMPLE_FACTORS 13158 CON-PV_0_13158 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):- | Drinking:Water Batch=5; Experiment=LC-MS; RAW_FILE_NAME=CON-PV_0_13158.mzXML SUBJECT_SAMPLE_FACTORS 12156 CON-PV_120_12156 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):120 | Drinking:Water Batch=5; Experiment=LC-MS; RAW_FILE_NAME=CON-PV_120_12156.mzXML SUBJECT_SAMPLE_FACTORS 12157 CON-PV_120_12157 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):120 | Drinking:Water Batch=5; Experiment=LC-MS; RAW_FILE_NAME=CON-PV_120_12157.mzXML SUBJECT_SAMPLE_FACTORS 12158 CON-PV_120_12158 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):120 | Drinking:Water Batch=5; Experiment=LC-MS; RAW_FILE_NAME=CON-PV_120_12158.mzXML SUBJECT_SAMPLE_FACTORS 12106 CON-PV_15_12106 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):15 | Drinking:Water Batch=4; Experiment=LC-MS; RAW_FILE_NAME=CON-PV_15_12106.mzXML SUBJECT_SAMPLE_FACTORS 12107 CON-PV_15_12107 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):15 | Drinking:Water Batch=4; Experiment=LC-MS; RAW_FILE_NAME=CON-PV_15_12107.mzXML SUBJECT_SAMPLE_FACTORS 12108 CON-PV_15_12108 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):15 | Drinking:Water Batch=4; Experiment=LC-MS; RAW_FILE_NAME=CON-PV_15_12108.mzXML SUBJECT_SAMPLE_FACTORS 12109 CON-PV_15_12109 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):15 | Drinking:Water Batch=4; Experiment=LC-MS; RAW_FILE_NAME=CON-PV_15_12109.mzXML SUBJECT_SAMPLE_FACTORS 12110 CON-PV_15_12110 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):15 | Drinking:Water Batch=4; Experiment=LC-MS; RAW_FILE_NAME=CON-PV_15_12110.mzXML SUBJECT_SAMPLE_FACTORS 12116 CON-PV_30_12116 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):30 | Drinking:Water Batch=4; Experiment=LC-MS; RAW_FILE_NAME=CON-PV_30_12116.mzXML SUBJECT_SAMPLE_FACTORS 12117 CON-PV_30_12117 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):30 | Drinking:Water Batch=4; Experiment=LC-MS; RAW_FILE_NAME=CON-PV_30_12117.mzXML SUBJECT_SAMPLE_FACTORS 12118 CON-PV_30_12118 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):30 | Drinking:Water Batch=4; Experiment=LC-MS; RAW_FILE_NAME=CON-PV_30_12118.mzXML SUBJECT_SAMPLE_FACTORS 12119 CON-PV_30_12119 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):30 | Drinking:Water Batch=4; Experiment=LC-MS; RAW_FILE_NAME=CON-PV_30_12119.mzXML SUBJECT_SAMPLE_FACTORS 12120 CON-PV_30_12120 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):30 | Drinking:Water Batch=4; Experiment=LC-MS; RAW_FILE_NAME=CON-PV_30_12120.mzXML SUBJECT_SAMPLE_FACTORS 12126 CON-PV_45_12126 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):45 | Drinking:Water Batch=3; Experiment=LC-MS; RAW_FILE_NAME=CON-PV_45_12126.mzXML SUBJECT_SAMPLE_FACTORS 12127 CON-PV_45_12127 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):45 | Drinking:Water Batch=3; Experiment=LC-MS; RAW_FILE_NAME=CON-PV_45_12127.mzXML SUBJECT_SAMPLE_FACTORS 12128 CON-PV_45_12128 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):45 | Drinking:Water Batch=3; Experiment=LC-MS; RAW_FILE_NAME=CON-PV_45_12128.mzXML SUBJECT_SAMPLE_FACTORS 12129 CON-PV_45_12129 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):45 | Drinking:Water Batch=3; Experiment=LC-MS; RAW_FILE_NAME=CON-PV_45_12129.mzXML SUBJECT_SAMPLE_FACTORS 12130 CON-PV_45_12130 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):45 | Drinking:Water Batch=3; Experiment=LC-MS; RAW_FILE_NAME=CON-PV_45_12130.mzXML SUBJECT_SAMPLE_FACTORS 12136 CON-PV_60_12136 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):60 | Drinking:Water Batch=3; Experiment=LC-MS; RAW_FILE_NAME=CON-PV_60_12136.mzXML SUBJECT_SAMPLE_FACTORS 12137 CON-PV_60_12137 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):60 | Drinking:Water Batch=3; Experiment=LC-MS; RAW_FILE_NAME=CON-PV_60_12137.mzXML SUBJECT_SAMPLE_FACTORS 12138 CON-PV_60_12138 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):60 | Drinking:Water Batch=3; Experiment=LC-MS; RAW_FILE_NAME=CON-PV_60_12138.mzXML SUBJECT_SAMPLE_FACTORS 12139 CON-PV_60_12139 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):60 | Drinking:Water Batch=3; Experiment=LC-MS; RAW_FILE_NAME=CON-PV_60_12139.mzXML SUBJECT_SAMPLE_FACTORS 12140 CON-PV_60_12140 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):60 | Drinking:Water Batch=3; Experiment=LC-MS; RAW_FILE_NAME=CON-PV_60_12140.mzXML SUBJECT_SAMPLE_FACTORS 12146 CON-PV_90_12146 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):90 | Drinking:Water Batch=5; Experiment=LC-MS; RAW_FILE_NAME=CON-PV_90_12146.mzXML SUBJECT_SAMPLE_FACTORS 12147 CON-PV_90_12147 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):90 | Drinking:Water Batch=5; Experiment=LC-MS; RAW_FILE_NAME=CON-PV_90_12147.mzXML SUBJECT_SAMPLE_FACTORS 12148 CON-PV_90_12148 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):90 | Drinking:Water Batch=5; Experiment=LC-MS; RAW_FILE_NAME=CON-PV_90_12148.mzXML SUBJECT_SAMPLE_FACTORS 12071 H12071 Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Fructose water Batch=8; Experiment=LC-MS; RAW_FILE_NAME=H12071.mzXML SUBJECT_SAMPLE_FACTORS 12091 H12091 Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Fructose water Batch=8; Experiment=LC-MS; RAW_FILE_NAME=H12091.mzXML SUBJECT_SAMPLE_FACTORS 12092 H12092 Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Fructose water Batch=8; Experiment=LC-MS; RAW_FILE_NAME=H12092.mzXML SUBJECT_SAMPLE_FACTORS 12093 H12093 Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Fructose water Batch=8; Experiment=LC-MS; RAW_FILE_NAME=H12093.mzXML SUBJECT_SAMPLE_FACTORS 12094 H12094 Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Fructose water Batch=8; Experiment=LC-MS; RAW_FILE_NAME=H12094.mzXML SUBJECT_SAMPLE_FACTORS 12095 H12095 Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Fructose water Batch=8; Experiment=LC-MS; RAW_FILE_NAME=H12095.mzXML SUBJECT_SAMPLE_FACTORS 12121 H12121_45_02 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Pancreas | Collection Time (minute):45 | Drinking:Water Batch=13; Experiment=MSI; RAW_FILE_NAME=H12121_45_02.mzXML SUBJECT_SAMPLE_FACTORS 12122 H12122_45_02 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Pancreas | Collection Time (minute):45 | Drinking:Water Batch=13; Experiment=MSI; RAW_FILE_NAME=H12122_45_02.mzXML SUBJECT_SAMPLE_FACTORS 12124 H12124_45_02 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Pancreas | Collection Time (minute):45 | Drinking:Water Batch=13; Experiment=MSI; RAW_FILE_NAME=H12124_45_02.mzXML SUBJECT_SAMPLE_FACTORS 12125 H12125_45_02 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Pancreas | Collection Time (minute):45 | Drinking:Water Batch=13; Experiment=MSI; RAW_FILE_NAME=H12125_45_02.mzXML SUBJECT_SAMPLE_FACTORS 12131 H12131_60_03 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Pancreas | Collection Time (minute):60 | Drinking:Water Batch=13; Experiment=MSI; RAW_FILE_NAME=H12131_60_03.mzXML SUBJECT_SAMPLE_FACTORS 12132 H12132_60_03 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Pancreas | Collection Time (minute):60 | Drinking:Water Batch=13; Experiment=MSI; RAW_FILE_NAME=H12132_60_03.mzXML SUBJECT_SAMPLE_FACTORS 12134 H12134_60_03 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Pancreas | Collection Time (minute):60 | Drinking:Water Batch=13; Experiment=MSI; RAW_FILE_NAME=H12134_60_03.mzXML SUBJECT_SAMPLE_FACTORS 12135 H12135_60_03 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Pancreas | Collection Time (minute):60 | Drinking:Water Batch=13; Experiment=MSI; RAW_FILE_NAME=H12135_60_03.mzXML SUBJECT_SAMPLE_FACTORS 13151 H13151_0_01 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Pancreas | Collection Time (minute):- | Drinking:Water Batch=13; Experiment=MSI; RAW_FILE_NAME=H13151_0_01.mzXML SUBJECT_SAMPLE_FACTORS 13152 H13152_0_01 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Pancreas | Collection Time (minute):- | Drinking:Water Batch=13; Experiment=MSI; RAW_FILE_NAME=H13152_0_01.mzXML SUBJECT_SAMPLE_FACTORS 13153 H13153_0_01 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Pancreas | Collection Time (minute):- | Drinking:Water Batch=13; Experiment=MSI; RAW_FILE_NAME=H13153_0_01.mzXML SUBJECT_SAMPLE_FACTORS 13154 H13154_0_01 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Pancreas | Collection Time (minute):- | Drinking:Water Batch=13; Experiment=MSI; RAW_FILE_NAME=H13154_0_01.mzXML SUBJECT_SAMPLE_FACTORS 13151 HFD-HV_0_13151 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Water Batch=5; Experiment=LC-MS; RAW_FILE_NAME=HFD-HV_0_13151.mzXML SUBJECT_SAMPLE_FACTORS 13152 HFD-HV_0_13152 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Water Batch=5; Experiment=LC-MS; RAW_FILE_NAME=HFD-HV_0_13152.mzXML SUBJECT_SAMPLE_FACTORS 13153 HFD-HV_0_13153 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Water Batch=5; Experiment=LC-MS; RAW_FILE_NAME=HFD-HV_0_13153.mzXML SUBJECT_SAMPLE_FACTORS 12151 HFD-HV_120_12151 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):120 | Drinking:Water Batch=5; Experiment=LC-MS; RAW_FILE_NAME=HFD-HV_120_12151.mzXML SUBJECT_SAMPLE_FACTORS 12152 HFD-HV_120_12152 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):120 | Drinking:Water Batch=5; Experiment=LC-MS; RAW_FILE_NAME=HFD-HV_120_12152.mzXML SUBJECT_SAMPLE_FACTORS 12153 HFD-HV_120_12153 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):120 | Drinking:Water Batch=5; Experiment=LC-MS; RAW_FILE_NAME=HFD-HV_120_12153.mzXML SUBJECT_SAMPLE_FACTORS 12101 HFD-HV_15_12101 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):15 | Drinking:Water Batch=4; Experiment=LC-MS; RAW_FILE_NAME=HFD-HV_15_12101.mzXML SUBJECT_SAMPLE_FACTORS 12102 HFD-HV_15_12102 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):15 | Drinking:Water Batch=4; Experiment=LC-MS; RAW_FILE_NAME=HFD-HV_15_12102.mzXML SUBJECT_SAMPLE_FACTORS 12103 HFD-HV_15_12103 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):15 | Drinking:Water Batch=4; Experiment=LC-MS; RAW_FILE_NAME=HFD-HV_15_12103.mzXML SUBJECT_SAMPLE_FACTORS 12104 HFD-HV_15_12104 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):15 | Drinking:Water Batch=4; Experiment=LC-MS; RAW_FILE_NAME=HFD-HV_15_12104.mzXML SUBJECT_SAMPLE_FACTORS 12105 HFD-HV_15_12105 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):15 | Drinking:Water Batch=4; Experiment=LC-MS; RAW_FILE_NAME=HFD-HV_15_12105.mzXML SUBJECT_SAMPLE_FACTORS 12121 HFD-HV_30_12121 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):30 | Drinking:Water Batch=4; Experiment=LC-MS; RAW_FILE_NAME=HFD-HV_30_12121.mzXML SUBJECT_SAMPLE_FACTORS 12122 HFD-HV_30_12122 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):30 | Drinking:Water Batch=4; Experiment=LC-MS; RAW_FILE_NAME=HFD-HV_30_12122.mzXML SUBJECT_SAMPLE_FACTORS 12123 HFD-HV_30_12123 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):30 | Drinking:Water Batch=4; Experiment=LC-MS; RAW_FILE_NAME=HFD-HV_30_12123.mzXML SUBJECT_SAMPLE_FACTORS 12124 HFD-HV_30_12124 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):30 | Drinking:Water Batch=4; Experiment=LC-MS; RAW_FILE_NAME=HFD-HV_30_12124.mzXML SUBJECT_SAMPLE_FACTORS 12125 HFD-HV_30_12125 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):30 | Drinking:Water Batch=4; Experiment=LC-MS; RAW_FILE_NAME=HFD-HV_30_12125.mzXML SUBJECT_SAMPLE_FACTORS 12121 HFD-HV_45_12121 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):45 | Drinking:Water Batch=3; Experiment=LC-MS; RAW_FILE_NAME=HFD-HV_45_12121.mzXML SUBJECT_SAMPLE_FACTORS 12122 HFD-HV_45_12122 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):45 | Drinking:Water Batch=3; Experiment=LC-MS; RAW_FILE_NAME=HFD-HV_45_12122.mzXML SUBJECT_SAMPLE_FACTORS 12123 HFD-HV_45_12123 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):45 | Drinking:Water Batch=3; Experiment=LC-MS; RAW_FILE_NAME=HFD-HV_45_12123.mzXML SUBJECT_SAMPLE_FACTORS 12124 HFD-HV_45_12124 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):45 | Drinking:Water Batch=3; Experiment=LC-MS; RAW_FILE_NAME=HFD-HV_45_12124.mzXML SUBJECT_SAMPLE_FACTORS 12125 HFD-HV_45_12125 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):45 | Drinking:Water Batch=3; Experiment=LC-MS; RAW_FILE_NAME=HFD-HV_45_12125.mzXML SUBJECT_SAMPLE_FACTORS 12121 HFD-HV_60_12121 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):60 | Drinking:Water Batch=3; Experiment=LC-MS; RAW_FILE_NAME=HFD-HV_60_12121.mzXML SUBJECT_SAMPLE_FACTORS 12122 HFD-HV_60_12122 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):60 | Drinking:Water Batch=3; Experiment=LC-MS; RAW_FILE_NAME=HFD-HV_60_12122.mzXML SUBJECT_SAMPLE_FACTORS 12123 HFD-HV_60_12123 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):60 | Drinking:Water Batch=3; Experiment=LC-MS; RAW_FILE_NAME=HFD-HV_60_12123.mzXML SUBJECT_SAMPLE_FACTORS 12124 HFD-HV_60_12124 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):60 | Drinking:Water Batch=3; Experiment=LC-MS; RAW_FILE_NAME=HFD-HV_60_12124.mzXML SUBJECT_SAMPLE_FACTORS 12125 HFD-HV_60_12125 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):60 | Drinking:Water Batch=3; Experiment=LC-MS; RAW_FILE_NAME=HFD-HV_60_12125.mzXML SUBJECT_SAMPLE_FACTORS 12141 HFD-HV_90_12141 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):90 | Drinking:Water Batch=5; Experiment=LC-MS; RAW_FILE_NAME=HFD-HV_90_12141.mzXML SUBJECT_SAMPLE_FACTORS 12142 HFD-HV_90_12142 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):90 | Drinking:Water Batch=5; Experiment=LC-MS; RAW_FILE_NAME=HFD-HV_90_12142.mzXML SUBJECT_SAMPLE_FACTORS 12143 HFD-HV_90_12143 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):90 | Drinking:Water Batch=5; Experiment=LC-MS; RAW_FILE_NAME=HFD-HV_90_12143.mzXML SUBJECT_SAMPLE_FACTORS 13151 HFD-PV_0_13151 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):- | Drinking:Water Batch=5; Experiment=LC-MS; RAW_FILE_NAME=HFD-PV_0_13151.mzXML SUBJECT_SAMPLE_FACTORS 13152 HFD-PV_0_13152 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):- | Drinking:Water Batch=5; Experiment=LC-MS; RAW_FILE_NAME=HFD-PV_0_13152.mzXML SUBJECT_SAMPLE_FACTORS 13153 HFD-PV_0_13153 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):- | Drinking:Water Batch=5; Experiment=LC-MS; RAW_FILE_NAME=HFD-PV_0_13153.mzXML SUBJECT_SAMPLE_FACTORS 12151 HFD-PV_120_12151 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):120 | Drinking:Water Batch=5; Experiment=LC-MS; RAW_FILE_NAME=HFD-PV_120_12151.mzXML SUBJECT_SAMPLE_FACTORS 12152 HFD-PV_120_12152 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):120 | Drinking:Water Batch=5; Experiment=LC-MS; RAW_FILE_NAME=HFD-PV_120_12152.mzXML SUBJECT_SAMPLE_FACTORS 12153 HFD-PV_120_12153 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):120 | Drinking:Water Batch=5; Experiment=LC-MS; RAW_FILE_NAME=HFD-PV_120_12153.mzXML SUBJECT_SAMPLE_FACTORS 12101 HFD-PV_15_12101 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):15 | Drinking:Water Batch=4; Experiment=LC-MS; RAW_FILE_NAME=HFD-PV_15_12101.mzXML SUBJECT_SAMPLE_FACTORS 12102 HFD-PV_15_12102 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):15 | Drinking:Water Batch=4; Experiment=LC-MS; RAW_FILE_NAME=HFD-PV_15_12102.mzXML SUBJECT_SAMPLE_FACTORS 12103 HFD-PV_15_12103 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):15 | Drinking:Water Batch=4; Experiment=LC-MS; RAW_FILE_NAME=HFD-PV_15_12103.mzXML SUBJECT_SAMPLE_FACTORS 12104 HFD-PV_15_12104 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):15 | Drinking:Water Batch=4; Experiment=LC-MS; RAW_FILE_NAME=HFD-PV_15_12104.mzXML SUBJECT_SAMPLE_FACTORS 12105 HFD-PV_15_12105 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):15 | Drinking:Water Batch=4; Experiment=LC-MS; RAW_FILE_NAME=HFD-PV_15_12105.mzXML SUBJECT_SAMPLE_FACTORS 12121 HFD-PV_30_12121 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):30 | Drinking:Water Batch=4; Experiment=LC-MS; RAW_FILE_NAME=HFD-PV_30_12121.mzXML SUBJECT_SAMPLE_FACTORS 12122 HFD-PV_30_12122 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):30 | Drinking:Water Batch=4; Experiment=LC-MS; RAW_FILE_NAME=HFD-PV_30_12122.mzXML SUBJECT_SAMPLE_FACTORS 12123 HFD-PV_30_12123 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):30 | Drinking:Water Batch=4; Experiment=LC-MS; RAW_FILE_NAME=HFD-PV_30_12123.mzXML SUBJECT_SAMPLE_FACTORS 12124 HFD-PV_30_12124 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):30 | Drinking:Water Batch=4; Experiment=LC-MS; RAW_FILE_NAME=HFD-PV_30_12124.mzXML SUBJECT_SAMPLE_FACTORS 12125 HFD-PV_30_12125 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):30 | Drinking:Water Batch=4; Experiment=LC-MS; RAW_FILE_NAME=HFD-PV_30_12125.mzXML SUBJECT_SAMPLE_FACTORS 12121 HFD-PV_45_12121 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):45 | Drinking:Water Batch=3; Experiment=LC-MS; RAW_FILE_NAME=HFD-PV_45_12121.mzXML SUBJECT_SAMPLE_FACTORS 12122 HFD-PV_45_12122 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):45 | Drinking:Water Batch=3; Experiment=LC-MS; RAW_FILE_NAME=HFD-PV_45_12122.mzXML SUBJECT_SAMPLE_FACTORS 12123 HFD-PV_45_12123 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):45 | Drinking:Water Batch=3; Experiment=LC-MS; RAW_FILE_NAME=HFD-PV_45_12123.mzXML SUBJECT_SAMPLE_FACTORS 12124 HFD-PV_45_12124 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):45 | Drinking:Water Batch=3; Experiment=LC-MS; RAW_FILE_NAME=HFD-PV_45_12124.mzXML SUBJECT_SAMPLE_FACTORS 12125 HFD-PV_45_12125 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):45 | Drinking:Water Batch=3; Experiment=LC-MS; RAW_FILE_NAME=HFD-PV_45_12125.mzXML SUBJECT_SAMPLE_FACTORS 12121 HFD-PV_60_12121 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):60 | Drinking:Water Batch=3; Experiment=LC-MS; RAW_FILE_NAME=HFD-PV_60_12121.mzXML SUBJECT_SAMPLE_FACTORS 12122 HFD-PV_60_12122 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):60 | Drinking:Water Batch=3; Experiment=LC-MS; RAW_FILE_NAME=HFD-PV_60_12122.mzXML SUBJECT_SAMPLE_FACTORS 12123 HFD-PV_60_12123 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):60 | Drinking:Water Batch=3; Experiment=LC-MS; RAW_FILE_NAME=HFD-PV_60_12123.mzXML SUBJECT_SAMPLE_FACTORS 12124 HFD-PV_60_12124 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):60 | Drinking:Water Batch=3; Experiment=LC-MS; RAW_FILE_NAME=HFD-PV_60_12124.mzXML SUBJECT_SAMPLE_FACTORS 12125 HFD-PV_60_12125 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):60 | Drinking:Water Batch=3; Experiment=LC-MS; RAW_FILE_NAME=HFD-PV_60_12125.mzXML SUBJECT_SAMPLE_FACTORS 12141 HFD-PV_90_12141 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):90 | Drinking:Water Batch=5; Experiment=LC-MS; RAW_FILE_NAME=HFD-PV_90_12141.mzXML SUBJECT_SAMPLE_FACTORS 12142 HFD-PV_90_12142 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):90 | Drinking:Water Batch=5; Experiment=LC-MS; RAW_FILE_NAME=HFD-PV_90_12142.mzXML SUBJECT_SAMPLE_FACTORS 12143 HFD-PV_90_12143 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):90 | Drinking:Water Batch=5; Experiment=LC-MS; RAW_FILE_NAME=HFD-PV_90_12143.mzXML SUBJECT_SAMPLE_FACTORS 7596 HV_7596 Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Batch=7; Experiment=LC-MS; RAW_FILE_NAME=HV_7596.mzXML SUBJECT_SAMPLE_FACTORS 7597 HV_7597 Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Batch=7; Experiment=LC-MS; RAW_FILE_NAME=HV_7597.mzXML SUBJECT_SAMPLE_FACTORS 931 HV_931 Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Batch=7; Experiment=LC-MS; RAW_FILE_NAME=HV_931.mzXML SUBJECT_SAMPLE_FACTORS 932 HV_932 Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Batch=7; Experiment=LC-MS; RAW_FILE_NAME=HV_932.mzXML SUBJECT_SAMPLE_FACTORS 933 HV_933 Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Batch=7; Experiment=LC-MS; RAW_FILE_NAME=HV_933.mzXML SUBJECT_SAMPLE_FACTORS 934 HV_934 Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Batch=7; Experiment=LC-MS; RAW_FILE_NAME=HV_934.mzXML SUBJECT_SAMPLE_FACTORS 935 HV_935 Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Batch=7; Experiment=LC-MS; RAW_FILE_NAME=HV_935.mzXML SUBJECT_SAMPLE_FACTORS 937 HV_937 Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Batch=7; Experiment=LC-MS; RAW_FILE_NAME=HV_937.mzXML SUBJECT_SAMPLE_FACTORS 938 HV_938 Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Batch=7; Experiment=LC-MS; RAW_FILE_NAME=HV_938.mzXML SUBJECT_SAMPLE_FACTORS 939 HV_939 Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Batch=7; Experiment=LC-MS; RAW_FILE_NAME=HV_939.mzXML SUBJECT_SAMPLE_FACTORS Intestine_01 Intestine_01 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Jejunum | Collection Time (minute):10 | Drinking:Water Batch=13; Experiment=LC-MS; RAW_FILE_NAME=Intestine_01.mzXML SUBJECT_SAMPLE_FACTORS 931 Jej_Group1_931 Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Jejunum | Collection Time (minute):10 | Drinking:Water Batch=2; Experiment=LC-MS; RAW_FILE_NAME=Jej_Group1_931.mzXML SUBJECT_SAMPLE_FACTORS 932 Jej_Group1_932 Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Jejunum | Collection Time (minute):10 | Drinking:Water Batch=2; Experiment=LC-MS; RAW_FILE_NAME=Jej_Group1_932.mzXML SUBJECT_SAMPLE_FACTORS 933 Jej_Group1_933 Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Jejunum | Collection Time (minute):10 | Drinking:Water Batch=2; Experiment=LC-MS; RAW_FILE_NAME=Jej_Group1_933.mzXML SUBJECT_SAMPLE_FACTORS 934 Jej_Group1_934 Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Jejunum | Collection Time (minute):10 | Drinking:Water Batch=2; Experiment=LC-MS; RAW_FILE_NAME=Jej_Group1_934.mzXML SUBJECT_SAMPLE_FACTORS 935 Jej_Group1_935 Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Jejunum | Collection Time (minute):10 | Drinking:Water Batch=2; Experiment=LC-MS; RAW_FILE_NAME=Jej_Group1_935.mzXML SUBJECT_SAMPLE_FACTORS 7596 Jej_Group2_7596 Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Jejunum | Collection Time (minute):10 | Drinking:Water Batch=2; Experiment=LC-MS; RAW_FILE_NAME=Jej_Group2_7596.mzXML SUBJECT_SAMPLE_FACTORS 7597 Jej_Group2_7597 Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Jejunum | Collection Time (minute):10 | Drinking:Water Batch=2; Experiment=LC-MS; RAW_FILE_NAME=Jej_Group2_7597.mzXML SUBJECT_SAMPLE_FACTORS 937 Jej_Group2_937 Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Jejunum | Collection Time (minute):10 | Drinking:Water Batch=2; Experiment=LC-MS; RAW_FILE_NAME=Jej_Group2_937.mzXML SUBJECT_SAMPLE_FACTORS 938 Jej_Group2_938 Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Jejunum | Collection Time (minute):10 | Drinking:Water Batch=2; Experiment=LC-MS; RAW_FILE_NAME=Jej_Group2_938.mzXML SUBJECT_SAMPLE_FACTORS 939 Jej_Group2_939 Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Jejunum | Collection Time (minute):10 | Drinking:Water Batch=2; Experiment=LC-MS; RAW_FILE_NAME=Jej_Group2_939.mzXML SUBJECT_SAMPLE_FACTORS 13163 Jej-13163 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Jejunum | Collection Time (minute):10 | Drinking:Water Batch=1; Experiment=LC-MS; RAW_FILE_NAME=Jej-13163.mzXML SUBJECT_SAMPLE_FACTORS 13166 Jej-13166 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Jejunum | Collection Time (minute):10 | Drinking:Water Batch=1; Experiment=LC-MS; RAW_FILE_NAME=Jej-13166.mzXML SUBJECT_SAMPLE_FACTORS 13167 Jej-13167 Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Jejunum | Collection Time (minute):10 | Drinking:Water Batch=1; Experiment=LC-MS; RAW_FILE_NAME=Jej-13167.mzXML SUBJECT_SAMPLE_FACTORS 13170 Jej-13170 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Jejunum | Collection Time (minute):10 | Drinking:Water Batch=1; Experiment=LC-MS; RAW_FILE_NAME=Jej-13170.mzXML SUBJECT_SAMPLE_FACTORS 13171 Jej-13171 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Jejunum | Collection Time (minute):10 | Drinking:Water Batch=1; Experiment=LC-MS; RAW_FILE_NAME=Jej-13171.mzXML SUBJECT_SAMPLE_FACTORS 13172 Jej-13172 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Jejunum | Collection Time (minute):10 | Drinking:Water Batch=1; Experiment=LC-MS; RAW_FILE_NAME=Jej-13172.mzXML SUBJECT_SAMPLE_FACTORS KHK_Gly_1 KHK_Gly_1_000 Genotype:KHK-c-KO | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Water Batch=12; Experiment=LC-MS; RAW_FILE_NAME=KHK_Gly_1_000.mzXML SUBJECT_SAMPLE_FACTORS KHK_Gly_1 KHK_Gly_1_010 Genotype:KHK-c-KO | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Batch=12; Experiment=LC-MS; RAW_FILE_NAME=KHK_Gly_1_010.mzXML SUBJECT_SAMPLE_FACTORS KHK_Gly_1 KHK_Gly_1_030 Genotype:KHK-c-KO | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):30 | Drinking:Water Batch=12; Experiment=LC-MS; RAW_FILE_NAME=KHK_Gly_1_030.mzXML SUBJECT_SAMPLE_FACTORS KHK_Gly_1 KHK_Gly_1_060 Genotype:KHK-c-KO | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):60 | Drinking:Water Batch=12; Experiment=LC-MS; RAW_FILE_NAME=KHK_Gly_1_060.mzXML SUBJECT_SAMPLE_FACTORS KHK_Gly_1 KHK_Gly_1_120 Genotype:KHK-c-KO | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):120 | Drinking:Water Batch=12; Experiment=LC-MS; RAW_FILE_NAME=KHK_Gly_1_120.mzXML SUBJECT_SAMPLE_FACTORS KHK_Gly_2 KHK_Gly_2_000 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Water Batch=12; Experiment=LC-MS; RAW_FILE_NAME=KHK_Gly_2_000.mzXML SUBJECT_SAMPLE_FACTORS KHK_Gly_2 KHK_Gly_2_010 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Batch=12; Experiment=LC-MS; RAW_FILE_NAME=KHK_Gly_2_010.mzXML SUBJECT_SAMPLE_FACTORS KHK_Gly_2 KHK_Gly_2_030 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):30 | Drinking:Water Batch=12; Experiment=LC-MS; RAW_FILE_NAME=KHK_Gly_2_030.mzXML SUBJECT_SAMPLE_FACTORS KHK_Gly_2 KHK_Gly_2_060 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):60 | Drinking:Water Batch=12; Experiment=LC-MS; RAW_FILE_NAME=KHK_Gly_2_060.mzXML SUBJECT_SAMPLE_FACTORS KHK_Gly_2 KHK_Gly_2_120 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):120 | Drinking:Water Batch=12; Experiment=LC-MS; RAW_FILE_NAME=KHK_Gly_2_120.mzXML SUBJECT_SAMPLE_FACTORS KHK_Gly_3 KHK_Gly_3_000 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Water Batch=12; Experiment=LC-MS; RAW_FILE_NAME=KHK_Gly_3_000.mzXML SUBJECT_SAMPLE_FACTORS KHK_Gly_3 KHK_Gly_3_010 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Batch=12; Experiment=LC-MS; RAW_FILE_NAME=KHK_Gly_3_010.mzXML SUBJECT_SAMPLE_FACTORS KHK_Gly_3 KHK_Gly_3_030 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):30 | Drinking:Water Batch=12; Experiment=LC-MS; RAW_FILE_NAME=KHK_Gly_3_030.mzXML SUBJECT_SAMPLE_FACTORS KHK_Gly_3 KHK_Gly_3_060 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):60 | Drinking:Water Batch=12; Experiment=LC-MS; RAW_FILE_NAME=KHK_Gly_3_060.mzXML SUBJECT_SAMPLE_FACTORS KHK_Gly_3 KHK_Gly_3_120 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):120 | Drinking:Water Batch=12; Experiment=LC-MS; RAW_FILE_NAME=KHK_Gly_3_120.mzXML SUBJECT_SAMPLE_FACTORS KHK_Gly_4 KHK_Gly_4_000 Genotype:KHK-c-KO | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Water Batch=12; Experiment=LC-MS; RAW_FILE_NAME=KHK_Gly_4_000.mzXML SUBJECT_SAMPLE_FACTORS KHK_Gly_4 KHK_Gly_4_010 Genotype:KHK-c-KO | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Batch=12; Experiment=LC-MS; RAW_FILE_NAME=KHK_Gly_4_010.mzXML SUBJECT_SAMPLE_FACTORS KHK_Gly_4 KHK_Gly_4_030 Genotype:KHK-c-KO | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):30 | Drinking:Water Batch=12; Experiment=LC-MS; RAW_FILE_NAME=KHK_Gly_4_030.mzXML SUBJECT_SAMPLE_FACTORS KHK_Gly_4 KHK_Gly_4_060 Genotype:KHK-c-KO | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):60 | Drinking:Water Batch=12; Experiment=LC-MS; RAW_FILE_NAME=KHK_Gly_4_060.mzXML SUBJECT_SAMPLE_FACTORS KHK_Gly_4 KHK_Gly_4_120 Genotype:KHK-c-KO | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):120 | Drinking:Water Batch=12; Experiment=LC-MS; RAW_FILE_NAME=KHK_Gly_4_120.mzXML SUBJECT_SAMPLE_FACTORS KHK_Gly_5 KHK_Gly_5_000 Genotype:KHK-c-KO | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Water Batch=12; Experiment=LC-MS; RAW_FILE_NAME=KHK_Gly_5_000.mzXML SUBJECT_SAMPLE_FACTORS KHK_Gly_5 KHK_Gly_5_010 Genotype:KHK-c-KO | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Batch=12; Experiment=LC-MS; RAW_FILE_NAME=KHK_Gly_5_010.mzXML SUBJECT_SAMPLE_FACTORS KHK_Gly_5 KHK_Gly_5_030 Genotype:KHK-c-KO | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):30 | Drinking:Water Batch=12; Experiment=LC-MS; RAW_FILE_NAME=KHK_Gly_5_030.mzXML SUBJECT_SAMPLE_FACTORS KHK_Gly_5 KHK_Gly_5_060 Genotype:KHK-c-KO | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):60 | Drinking:Water Batch=12; Experiment=LC-MS; RAW_FILE_NAME=KHK_Gly_5_060.mzXML SUBJECT_SAMPLE_FACTORS KHK_Gly_5 KHK_Gly_5_120 Genotype:KHK-c-KO | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):120 | Drinking:Water Batch=12; Experiment=LC-MS; RAW_FILE_NAME=KHK_Gly_5_120.mzXML SUBJECT_SAMPLE_FACTORS KHK_Gly_6 KHK_Gly_6_000 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Water Batch=12; Experiment=LC-MS; RAW_FILE_NAME=KHK_Gly_6_000.mzXML SUBJECT_SAMPLE_FACTORS KHK_Gly_6 KHK_Gly_6_010 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Batch=12; Experiment=LC-MS; RAW_FILE_NAME=KHK_Gly_6_010.mzXML SUBJECT_SAMPLE_FACTORS KHK_Gly_6 KHK_Gly_6_030 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):30 | Drinking:Water Batch=12; Experiment=LC-MS; RAW_FILE_NAME=KHK_Gly_6_030.mzXML SUBJECT_SAMPLE_FACTORS KHK_Gly_6 KHK_Gly_6_060 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):60 | Drinking:Water Batch=12; Experiment=LC-MS; RAW_FILE_NAME=KHK_Gly_6_060.mzXML SUBJECT_SAMPLE_FACTORS KHK_Gly_6 KHK_Gly_6_120 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):120 | Drinking:Water Batch=12; Experiment=LC-MS; RAW_FILE_NAME=KHK_Gly_6_120.mzXML SUBJECT_SAMPLE_FACTORS 12086 L12086 Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Fructose water Batch=8; Experiment=LC-MS; RAW_FILE_NAME=L12086.mzXML SUBJECT_SAMPLE_FACTORS 12096 L12096 Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Fructose water Batch=8; Experiment=LC-MS; RAW_FILE_NAME=L12096.mzXML SUBJECT_SAMPLE_FACTORS 12097 L12097 Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Fructose water Batch=8; Experiment=LC-MS; RAW_FILE_NAME=L12097.mzXML SUBJECT_SAMPLE_FACTORS 12098 L12098 Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Fructose water Batch=8; Experiment=LC-MS; RAW_FILE_NAME=L12098.mzXML SUBJECT_SAMPLE_FACTORS 12099 L12099 Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Fructose water Batch=8; Experiment=LC-MS; RAW_FILE_NAME=L12099.mzXML SUBJECT_SAMPLE_FACTORS 12100 L12100 Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Fructose water Batch=8; Experiment=LC-MS; RAW_FILE_NAME=L12100.mzXML SUBJECT_SAMPLE_FACTORS 12126 L12126_45_02 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Pancreas | Collection Time (minute):45 | Drinking:Water Batch=13; Experiment=MSI; RAW_FILE_NAME=L12126_45_02.mzXML SUBJECT_SAMPLE_FACTORS 12128 L12128_45_02 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Pancreas | Collection Time (minute):45 | Drinking:Water Batch=13; Experiment=MSI; RAW_FILE_NAME=L12128_45_02.mzXML SUBJECT_SAMPLE_FACTORS 12129 L12129_45_02 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Pancreas | Collection Time (minute):45 | Drinking:Water Batch=13; Experiment=MSI; RAW_FILE_NAME=L12129_45_02.mzXML SUBJECT_SAMPLE_FACTORS 12130 L12130_45_02 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Pancreas | Collection Time (minute):45 | Drinking:Water Batch=13; Experiment=MSI; RAW_FILE_NAME=L12130_45_02.mzXML SUBJECT_SAMPLE_FACTORS 12136 L12136_60_03 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Pancreas | Collection Time (minute):60 | Drinking:Water Batch=13; Experiment=MSI; RAW_FILE_NAME=L12136_60_03.mzXML SUBJECT_SAMPLE_FACTORS 12137 L12137_60_03 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Pancreas | Collection Time (minute):60 | Drinking:Water Batch=13; Experiment=MSI; RAW_FILE_NAME=L12137_60_03.mzXML SUBJECT_SAMPLE_FACTORS 12139 L12139_60_03 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Pancreas | Collection Time (minute):60 | Drinking:Water Batch=13; Experiment=MSI; RAW_FILE_NAME=L12139_60_03.mzXML SUBJECT_SAMPLE_FACTORS 12140 L12140_60_03 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Pancreas | Collection Time (minute):60 | Drinking:Water Batch=13; Experiment=MSI; RAW_FILE_NAME=L12140_60_03.mzXML SUBJECT_SAMPLE_FACTORS 13156 L13156_0_01 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Pancreas | Collection Time (minute):- | Drinking:Water Batch=13; Experiment=MSI; RAW_FILE_NAME=L13156_0_01.mzXML SUBJECT_SAMPLE_FACTORS 13157 L13157_0_01 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Pancreas | Collection Time (minute):- | Drinking:Water Batch=13; Experiment=MSI; RAW_FILE_NAME=L13157_0_01.mzXML SUBJECT_SAMPLE_FACTORS 13159 L13159_0_01 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Pancreas | Collection Time (minute):- | Drinking:Water Batch=13; Experiment=MSI; RAW_FILE_NAME=L13159_0_01.mzXML SUBJECT_SAMPLE_FACTORS 13160 L13160_0_01 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Pancreas | Collection Time (minute):- | Drinking:Water Batch=13; Experiment=MSI; RAW_FILE_NAME=L13160_0_01.mzXML SUBJECT_SAMPLE_FACTORS 931 Liver_Group1_931 Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Liver | Collection Time (minute):10 | Drinking:Water Batch=2; Experiment=LC-MS; RAW_FILE_NAME=Liver_Group1_931.mzXML SUBJECT_SAMPLE_FACTORS 932 Liver_Group1_932 Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Liver | Collection Time (minute):10 | Drinking:Water Batch=2; Experiment=LC-MS; RAW_FILE_NAME=Liver_Group1_932.mzXML SUBJECT_SAMPLE_FACTORS 933 Liver_Group1_933 Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Liver | Collection Time (minute):10 | Drinking:Water Batch=2; Experiment=LC-MS; RAW_FILE_NAME=Liver_Group1_933.mzXML SUBJECT_SAMPLE_FACTORS 934 Liver_Group1_934 Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Liver | Collection Time (minute):10 | Drinking:Water Batch=2; Experiment=LC-MS; RAW_FILE_NAME=Liver_Group1_934.mzXML SUBJECT_SAMPLE_FACTORS 935 Liver_Group1_935 Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Liver | Collection Time (minute):10 | Drinking:Water Batch=2; Experiment=LC-MS; RAW_FILE_NAME=Liver_Group1_935.mzXML SUBJECT_SAMPLE_FACTORS 7596 Liver_Group2_7596 Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Liver | Collection Time (minute):10 | Drinking:Water Batch=2; Experiment=LC-MS; RAW_FILE_NAME=Liver_Group2_7596.mzXML SUBJECT_SAMPLE_FACTORS 7597 Liver_Group2_7597 Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Liver | Collection Time (minute):10 | Drinking:Water Batch=2; Experiment=LC-MS; RAW_FILE_NAME=Liver_Group2_7597.mzXML SUBJECT_SAMPLE_FACTORS 937 Liver_Group2_937 Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Liver | Collection Time (minute):10 | Drinking:Water Batch=2; Experiment=LC-MS; RAW_FILE_NAME=Liver_Group2_937.mzXML SUBJECT_SAMPLE_FACTORS 938 Liver_Group2_938 Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Liver | Collection Time (minute):10 | Drinking:Water Batch=2; Experiment=LC-MS; RAW_FILE_NAME=Liver_Group2_938.mzXML SUBJECT_SAMPLE_FACTORS 939 Liver_Group2_939 Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Liver | Collection Time (minute):10 | Drinking:Water Batch=2; Experiment=LC-MS; RAW_FILE_NAME=Liver_Group2_939.mzXML SUBJECT_SAMPLE_FACTORS Ms1 Ms1_T0 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):- | Drinking:Water Batch=9; Experiment=LC-MS; RAW_FILE_NAME=Ms1_T0.mzXML SUBJECT_SAMPLE_FACTORS Ms1 Ms1_T15 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):15 | Drinking:Water Batch=9; Experiment=LC-MS; RAW_FILE_NAME=Ms1_T15.mzXML SUBJECT_SAMPLE_FACTORS Ms1 Ms1_T45 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):45 | Drinking:Water Batch=9; Experiment=LC-MS; RAW_FILE_NAME=Ms1_T45.mzXML SUBJECT_SAMPLE_FACTORS Ms1 Ms1_T90 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):90 | Drinking:Water Batch=9; Experiment=LC-MS; RAW_FILE_NAME=Ms1_T90.mzXML SUBJECT_SAMPLE_FACTORS Ms1 Ms10_T0 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):- | Drinking:Water Batch=10; Experiment=LC-MS; RAW_FILE_NAME=Ms10_T0.mzXML SUBJECT_SAMPLE_FACTORS Ms1 Ms10_T120 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):120 | Drinking:Water Batch=10; Experiment=LC-MS; RAW_FILE_NAME=Ms10_T120.mzXML SUBJECT_SAMPLE_FACTORS Ms1 Ms10_T30 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):30 | Drinking:Water Batch=10; Experiment=LC-MS; RAW_FILE_NAME=Ms10_T30.mzXML SUBJECT_SAMPLE_FACTORS Ms1 Ms10_T60 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):60 | Drinking:Water Batch=10; Experiment=LC-MS; RAW_FILE_NAME=Ms10_T60.mzXML SUBJECT_SAMPLE_FACTORS Ms2 Ms2_T0 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):- | Drinking:Water Batch=9; Experiment=LC-MS; RAW_FILE_NAME=Ms2_T0.mzXML SUBJECT_SAMPLE_FACTORS Ms2 Ms2_T15 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):15 | Drinking:Water Batch=9; Experiment=LC-MS; RAW_FILE_NAME=Ms2_T15.mzXML SUBJECT_SAMPLE_FACTORS Ms2 Ms2_T45 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):45 | Drinking:Water Batch=9; Experiment=LC-MS; RAW_FILE_NAME=Ms2_T45.mzXML SUBJECT_SAMPLE_FACTORS Ms2 Ms2_T90 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):90 | Drinking:Water Batch=9; Experiment=LC-MS; RAW_FILE_NAME=Ms2_T90.mzXML SUBJECT_SAMPLE_FACTORS Ms3 Ms3_T0 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):- | Drinking:Water Batch=9; Experiment=LC-MS; RAW_FILE_NAME=Ms3_T0.mzXML SUBJECT_SAMPLE_FACTORS Ms3 Ms3_T15 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):15 | Drinking:Water Batch=9; Experiment=LC-MS; RAW_FILE_NAME=Ms3_T15.mzXML SUBJECT_SAMPLE_FACTORS Ms3 Ms3_T45 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):45 | Drinking:Water Batch=9; Experiment=LC-MS; RAW_FILE_NAME=Ms3_T45.mzXML SUBJECT_SAMPLE_FACTORS Ms3 Ms3_T90 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):90 | Drinking:Water Batch=9; Experiment=LC-MS; RAW_FILE_NAME=Ms3_T90.mzXML SUBJECT_SAMPLE_FACTORS Ms4 Ms4_T0 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):- | Drinking:Water Batch=9; Experiment=LC-MS; RAW_FILE_NAME=Ms4_T0.mzXML SUBJECT_SAMPLE_FACTORS Ms4 Ms4_T15 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):15 | Drinking:Water Batch=9; Experiment=LC-MS; RAW_FILE_NAME=Ms4_T15.mzXML SUBJECT_SAMPLE_FACTORS Ms4 Ms4_T45 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):45 | Drinking:Water Batch=9; Experiment=LC-MS; RAW_FILE_NAME=Ms4_T45.mzXML SUBJECT_SAMPLE_FACTORS Ms4 Ms4_T90 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):90 | Drinking:Water Batch=9; Experiment=LC-MS; RAW_FILE_NAME=Ms4_T90.mzXML SUBJECT_SAMPLE_FACTORS Ms5 Ms5_T0 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):- | Drinking:Water Batch=10; Experiment=LC-MS; RAW_FILE_NAME=Ms5_T0.mzXML SUBJECT_SAMPLE_FACTORS Ms5 Ms5_T15 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):15 | Drinking:Water Batch=10; Experiment=LC-MS; RAW_FILE_NAME=Ms5_T15.mzXML SUBJECT_SAMPLE_FACTORS Ms5 Ms5_T45 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):45 | Drinking:Water Batch=10; Experiment=LC-MS; RAW_FILE_NAME=Ms5_T45.mzXML SUBJECT_SAMPLE_FACTORS Ms5 Ms5_T90 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):90 | Drinking:Water Batch=10; Experiment=LC-MS; RAW_FILE_NAME=Ms5_T90.mzXML SUBJECT_SAMPLE_FACTORS Ms6 Ms6_T0 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):- | Drinking:Water Batch=9; Experiment=LC-MS; RAW_FILE_NAME=Ms6_T0.mzXML SUBJECT_SAMPLE_FACTORS Ms6 Ms6_T120 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):120 | Drinking:Water Batch=9; Experiment=LC-MS; RAW_FILE_NAME=Ms6_T120.mzXML SUBJECT_SAMPLE_FACTORS Ms6 Ms6_T30 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):30 | Drinking:Water Batch=9; Experiment=LC-MS; RAW_FILE_NAME=Ms6_T30.mzXML SUBJECT_SAMPLE_FACTORS Ms6 Ms6_T60 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):60 | Drinking:Water Batch=9; Experiment=LC-MS; RAW_FILE_NAME=Ms6_T60.mzXML SUBJECT_SAMPLE_FACTORS Ms7 Ms7_T0 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):- | Drinking:Water Batch=9; Experiment=LC-MS; RAW_FILE_NAME=Ms7_T0.mzXML SUBJECT_SAMPLE_FACTORS Ms7 Ms7_T120 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):120 | Drinking:Water Batch=9; Experiment=LC-MS; RAW_FILE_NAME=Ms7_T120.mzXML SUBJECT_SAMPLE_FACTORS Ms7 Ms7_T30 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):30 | Drinking:Water Batch=9; Experiment=LC-MS; RAW_FILE_NAME=Ms7_T30.mzXML SUBJECT_SAMPLE_FACTORS Ms7 Ms7_T60 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):60 | Drinking:Water Batch=9; Experiment=LC-MS; RAW_FILE_NAME=Ms7_T60.mzXML SUBJECT_SAMPLE_FACTORS Ms8 Ms8_T0 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):- | Drinking:Water Batch=9; Experiment=LC-MS; RAW_FILE_NAME=Ms8_T0.mzXML SUBJECT_SAMPLE_FACTORS Ms8 Ms8_T120 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):120 | Drinking:Water Batch=9; Experiment=LC-MS; RAW_FILE_NAME=Ms8_T120.mzXML SUBJECT_SAMPLE_FACTORS Ms8 Ms8_T30 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):30 | Drinking:Water Batch=9; Experiment=LC-MS; RAW_FILE_NAME=Ms8_T30.mzXML SUBJECT_SAMPLE_FACTORS Ms8 Ms8_T60 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):60 | Drinking:Water Batch=9; Experiment=LC-MS; RAW_FILE_NAME=Ms8_T60.mzXML SUBJECT_SAMPLE_FACTORS Ms9 Ms9_T0 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):- | Drinking:Water Batch=9; Experiment=LC-MS; RAW_FILE_NAME=Ms9_T0.mzXML SUBJECT_SAMPLE_FACTORS Ms9 Ms9_T120 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):120 | Drinking:Water Batch=9; Experiment=LC-MS; RAW_FILE_NAME=Ms9_T120.mzXML SUBJECT_SAMPLE_FACTORS Ms9 Ms9_T30 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):30 | Drinking:Water Batch=9; Experiment=LC-MS; RAW_FILE_NAME=Ms9_T30.mzXML SUBJECT_SAMPLE_FACTORS Ms9 Ms9_T60 Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):60 | Drinking:Water Batch=9; Experiment=LC-MS; RAW_FILE_NAME=Ms9_T60.mzXML SUBJECT_SAMPLE_FACTORS 7596 PV_7596 Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):10 | Drinking:Water Batch=7; Experiment=LC-MS; RAW_FILE_NAME=PV_7596.mzXML SUBJECT_SAMPLE_FACTORS 7597 PV_7597 Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):10 | Drinking:Water Batch=7; Experiment=LC-MS; RAW_FILE_NAME=PV_7597.mzXML SUBJECT_SAMPLE_FACTORS 931 PV_931 Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):10 | Drinking:Water Batch=7; Experiment=LC-MS; RAW_FILE_NAME=PV_931.mzXML SUBJECT_SAMPLE_FACTORS 932 PV_932 Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):10 | Drinking:Water Batch=7; Experiment=LC-MS; RAW_FILE_NAME=PV_932.mzXML SUBJECT_SAMPLE_FACTORS 933 PV_933 Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):10 | Drinking:Water Batch=7; Experiment=LC-MS; RAW_FILE_NAME=PV_933.mzXML SUBJECT_SAMPLE_FACTORS 934 PV_934 Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):10 | Drinking:Water Batch=7; Experiment=LC-MS; RAW_FILE_NAME=PV_934.mzXML SUBJECT_SAMPLE_FACTORS 935 PV_935 Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):10 | Drinking:Water Batch=7; Experiment=LC-MS; RAW_FILE_NAME=PV_935.mzXML SUBJECT_SAMPLE_FACTORS 937 PV_937 Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):10 | Drinking:Water Batch=7; Experiment=LC-MS; RAW_FILE_NAME=PV_937.mzXML SUBJECT_SAMPLE_FACTORS 938 PV_938 Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):10 | Drinking:Water Batch=7; Experiment=LC-MS; RAW_FILE_NAME=PV_938.mzXML SUBJECT_SAMPLE_FACTORS 939 PV_939 Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):10 | Drinking:Water Batch=7; Experiment=LC-MS; RAW_FILE_NAME=PV_939.mzXML SUBJECT_SAMPLE_FACTORS 13634 Unlabeled_LC-HV_13634 Genotype:Wild-type | Diet:CD | Diet Duration:12 weeks | Treatment:Saline injection | Tissue:Systemic Serum | Collection Time (minute):1440 | Drinking:Water Batch=11; Experiment=LC-MS; RAW_FILE_NAME=Unlabeled_LC-HV_13634.mzXML SUBJECT_SAMPLE_FACTORS 13635 Unlabeled_LC-HV_13635 Genotype:Wild-type | Diet:CD | Diet Duration:12 weeks | Treatment:Saline injection | Tissue:Systemic Serum | Collection Time (minute):1440 | Drinking:Water Batch=11; Experiment=LC-MS; RAW_FILE_NAME=Unlabeled_LC-HV_13635.mzXML SUBJECT_SAMPLE_FACTORS 13637 Unlabeled_LC-HV_13637 Genotype:Wild-type | Diet:CD | Diet Duration:12 weeks | Treatment:Saline injection | Tissue:Systemic Serum | Collection Time (minute):1440 | Drinking:Water Batch=11; Experiment=LC-MS; RAW_FILE_NAME=Unlabeled_LC-HV_13637.mzXML SUBJECT_SAMPLE_FACTORS 13642 Unlabeled_LC-HV_13642 Genotype:Wild-type | Diet:CD | Diet Duration:12 weeks | Treatment:Saline injection | Tissue:Systemic Serum | Collection Time (minute):1440 | Drinking:Water Batch=11; Experiment=LC-MS; RAW_FILE_NAME=Unlabeled_LC-HV_13642.mzXML SUBJECT_SAMPLE_FACTORS 13646 Unlabeled_LC-HV_13646 Genotype:Wild-type | Diet:CD | Diet Duration:12 weeks | Treatment:Saline injection | Tissue:Systemic Serum | Collection Time (minute):1440 | Drinking:Water Batch=11; Experiment=LC-MS; RAW_FILE_NAME=Unlabeled_LC-HV_13646.mzXML SUBJECT_SAMPLE_FACTORS 13683 Unlabeled_LC-HV_13683 Genotype:Wild-type | Diet:CD | Diet Duration:12 weeks | Treatment:Saline injection | Tissue:Systemic Serum | Collection Time (minute):1440 | Drinking:Water Batch=11; Experiment=LC-MS; RAW_FILE_NAME=Unlabeled_LC-HV_13683.mzXML SUBJECT_SAMPLE_FACTORS 13626 Unlabeled_LF-HV_13626 Genotype:Wild-type | Diet:CD | Diet Duration:12 weeks | Treatment:Fructose injection | Tissue:Systemic Serum | Collection Time (minute):1440 | Drinking:Water Batch=11; Experiment=LC-MS; RAW_FILE_NAME=Unlabeled_LF-HV_13626.mzXML SUBJECT_SAMPLE_FACTORS 13627 Unlabeled_LF-HV_13627 Genotype:Wild-type | Diet:CD | Diet Duration:12 weeks | Treatment:Fructose injection | Tissue:Systemic Serum | Collection Time (minute):1440 | Drinking:Water Batch=11; Experiment=LC-MS; RAW_FILE_NAME=Unlabeled_LF-HV_13627.mzXML SUBJECT_SAMPLE_FACTORS 13628 Unlabeled_LF-HV_13628 Genotype:Wild-type | Diet:CD | Diet Duration:12 weeks | Treatment:Fructose injection | Tissue:Systemic Serum | Collection Time (minute):1440 | Drinking:Water Batch=11; Experiment=LC-MS; RAW_FILE_NAME=Unlabeled_LF-HV_13628.mzXML SUBJECT_SAMPLE_FACTORS 13631 Unlabeled_LF-HV_13631 Genotype:Wild-type | Diet:CD | Diet Duration:12 weeks | Treatment:Fructose injection | Tissue:Systemic Serum | Collection Time (minute):1440 | Drinking:Water Batch=11; Experiment=LC-MS; RAW_FILE_NAME=Unlabeled_LF-HV_13631.mzXML SUBJECT_SAMPLE_FACTORS 6348 Unlabeled_LF-HV_6348 Genotype:Wild-type | Diet:CD | Diet Duration:12 weeks | Treatment:Fructose injection | Tissue:Systemic Serum | Collection Time (minute):1440 | Drinking:Water Batch=11; Experiment=LC-MS; RAW_FILE_NAME=Unlabeled_LF-HV_6348.mzXML SUBJECT_SAMPLE_FACTORS 10632 Unlabeled_LH-HV_10632 Genotype:Wild-type | Diet:CD | Diet Duration:12 weeks | Treatment:Glycerate injection | Tissue:Systemic Serum | Collection Time (minute):1440 | Drinking:Water Batch=11; Experiment=LC-MS; RAW_FILE_NAME=Unlabeled_LH-HV_10632.mzXML SUBJECT_SAMPLE_FACTORS 10684 Unlabeled_LH-HV_10684 Genotype:Wild-type | Diet:CD | Diet Duration:12 weeks | Treatment:Glycerate injection | Tissue:Systemic Serum | Collection Time (minute):1440 | Drinking:Water Batch=11; Experiment=LC-MS; RAW_FILE_NAME=Unlabeled_LH-HV_10684.mzXML SUBJECT_SAMPLE_FACTORS 914 Unlabeled_LH-HV_914 Genotype:Wild-type | Diet:CD | Diet Duration:12 weeks | Treatment:Glycerate injection | Tissue:Systemic Serum | Collection Time (minute):1440 | Drinking:Water Batch=11; Experiment=LC-MS; RAW_FILE_NAME=Unlabeled_LH-HV_914.mzXML SUBJECT_SAMPLE_FACTORS 916 Unlabeled_LH-HV_916 Genotype:Wild-type | Diet:CD | Diet Duration:12 weeks | Treatment:Glycerate injection | Tissue:Systemic Serum | Collection Time (minute):1440 | Drinking:Water Batch=11; Experiment=LC-MS; RAW_FILE_NAME=Unlabeled_LH-HV_916.mzXML SUBJECT_SAMPLE_FACTORS 917 Unlabeled_LH-HV_917 Genotype:Wild-type | Diet:CD | Diet Duration:12 weeks | Treatment:Glycerate injection | Tissue:Systemic Serum | Collection Time (minute):1440 | Drinking:Water Batch=11; Experiment=LC-MS; RAW_FILE_NAME=Unlabeled_LH-HV_917.mzXML #COLLECTION CO:COLLECTION_SUMMARY After 3 days or 4 weeks of either HFD or CD feeding, each mouse was CO:COLLECTION_SUMMARY administrated a 1g/kg U-13C fructose oral gavage. Mice were anesthetized with 2% CO:COLLECTION_SUMMARY isoflurane, and their abdominal cavities were opened at the specified time. CO:COLLECTION_SUMMARY Abdominal tissues were displaced to identify the portal vein, and a 27G needle CO:COLLECTION_SUMMARY was used to immediately collect portal vein blood samples (~100 µL). CO:COLLECTION_SUMMARY Immediately after, cardiac blood was collected from the right ventricle using a CO:COLLECTION_SUMMARY 25G needle (~1 mL). The jejunum, pancreas, and liver tissues were quickly CO:COLLECTION_SUMMARY resected and snap-frozen in liquid nitrogen. Blood samples were placed on ice in CO:COLLECTION_SUMMARY the absence of anticoagulant for 20 minutes and centrifuged at 16,000 × g for CO:COLLECTION_SUMMARY 10 minutes at 4 °C to separate the serum and plasma fractions of each sample. CO:COLLECTION_SUMMARY Serum and tissue samples were kept at −80 °C until further analysis. CO:COLLECTION_PROTOCOL_FILENAME cwwong_methods.pdf CO:SAMPLE_TYPE Tissue #TREATMENT TR:TREATMENT_SUMMARY After 3 days or 4 weeks of either HFD or CD feeding, each mouse was TR:TREATMENT_SUMMARY administrated a 1g/kg U-13C fructose oral gavage. For ad-lib fructose feeding TR:TREATMENT_SUMMARY experiments, mice were fed fructose in the drinking water (15% w/v) for 4 weeks. TR:TREATMENT_SUMMARY Saline, fructose and glycerate injection were done in CD-fed mice for 12 weeks. TR:TREATMENT_SUMMARY For glycerate kinetic study, glycerate injections were performed in TR:TREATMENT_SUMMARY treatment-navie mice. #SAMPLEPREP SP:SAMPLEPREP_SUMMARY For LC-MS: Metabolites were extracted using a protocol optimized for SP:SAMPLEPREP_SUMMARY water-soluble polar metabolite analysis using liquid chromatography coupled with SP:SAMPLEPREP_SUMMARY mass spectrometry. All extraction buffers were stored at -20°C prior to usage SP:SAMPLEPREP_SUMMARY and immediately preceding the metabolite extraction. For serum samples, a 10 μL SP:SAMPLEPREP_SUMMARY serum aliquot was used for fructose tracing. Metabolites were extracted with 40 SP:SAMPLEPREP_SUMMARY μL of ice-cold methanol and incubated at -20 °C for 20 minutes. The clean SP:SAMPLEPREP_SUMMARY supernatant was collected after centrifugation for 10 minutes at the highest SP:SAMPLEPREP_SUMMARY speed, and the leftover pellet was further treated with 200 µL cold extraction SP:SAMPLEPREP_SUMMARY buffer (40:40:20 v/v/v methanol:acetonitrile:water solution) and left to SP:SAMPLEPREP_SUMMARY incubate on crushed ice for an additional 10 minutes. Following an additional 10 SP:SAMPLEPREP_SUMMARY minutes of centrifugation at the highest speed, the clean supernatant was SP:SAMPLEPREP_SUMMARY collected and pooled with the supernatant from the first collection. For tissue SP:SAMPLEPREP_SUMMARY samples, the extraction buffer used was a (v/v/v) solution of 40:40:20 SP:SAMPLEPREP_SUMMARY (methanol:acetonitrile:water) + 0.1 M formic acid. An aliquot volume equivalent SP:SAMPLEPREP_SUMMARY to 20x the sample weight was added to the Eppendorf tube with the homogenized SP:SAMPLEPREP_SUMMARY sample, vortexed for 10 seconds, and left to chill on crushed ice for 10 SP:SAMPLEPREP_SUMMARY minutes. The samples were then centrifuged for 10 minutes at the highest speed SP:SAMPLEPREP_SUMMARY at 4°C. The supernatant was transferred to a correspondingly labeled and SP:SAMPLEPREP_SUMMARY chilled Eppendorf tube, and the process was repeated once more. The total volume SP:SAMPLEPREP_SUMMARY of supernatant was then centrifuged for an additional 10 minutes. After SP:SAMPLEPREP_SUMMARY centrifugation, a final 500µL aliquot of the homogenate was then pipetted to a SP:SAMPLEPREP_SUMMARY second clean Eppendorf tube, to which 44µL of 15% (m/v) NH4HCO3 was added to SP:SAMPLEPREP_SUMMARY neutralize the acid in the buffer and precipitate the protein. This is the final SP:SAMPLEPREP_SUMMARY sample extract to be vialed and loaded to the instrument for analysis. SP:SAMPLEPREP_SUMMARY Metabolite extracts were stored at -80 °C until analysis. For MSI: Pancreas SP:SAMPLEPREP_SUMMARY tissues were first equilibrated to -15°C then sectioned to 20 µm thickness SP:SAMPLEPREP_SUMMARY using a Leica CM1950 cryostat (Buffalo Grove, IL, USA). Cut sections were then SP:SAMPLEPREP_SUMMARY thaw-mounted on clean microscope slides (1 mm height, plain, Fisher Scientific, SP:SAMPLEPREP_SUMMARY Pittsburgh, PA) and stored at -80 °C until IR-MALDESI-MSI analysis. Tissues SP:SAMPLEPREP_SUMMARY were first blocked into four groups, each containing one replicate of each SP:SAMPLEPREP_SUMMARY condition. Tissues were both cut and imaged in randomized order within these SP:SAMPLEPREP_SUMMARY blocks to minimize sampling bias. #CHROMATOGRAPHY CH:CHROMATOGRAPHY_TYPE HILIC CH:INSTRUMENT_NAME Thermo Vanquish CH:COLUMN_NAME Waters XBridge BEH Amide (150 mm × 2.1 mm, 2.5 μm) #ANALYSIS AN:ANALYSIS_TYPE MS AN:ANALYSIS_PROTOCOL_FILE cwwong_methods.pdf #MS MS:INSTRUMENT_NAME Thermo Q Exactive Plus Orbitrap MS:INSTRUMENT_TYPE Orbitrap MS:MS_TYPE ESI MS:ION_MODE NEGATIVE MS:MS_COMMENTS Fullscan mass spectrometry. The full scan mass spectrometry analysis was MS:MS_COMMENTS performed on a Thermo Q Exactive PLUS with a HESI source which was set to a MS:MS_COMMENTS spray voltage of -2.7kV under negative mode and 3.5kV under positive mode. The MS:MS_COMMENTS sheath, auxiliary, and sweep gas flow rates of 40, 10, and 2 (arbitrary unit), MS:MS_COMMENTS respectively. The capillary temperature was set to 300°C, and the aux gas MS:MS_COMMENTS heater was 360°C. The S-lens RF level was 45. The m/z range was set to 72 to MS:MS_COMMENTS 1000 m/z under both positive and negative ionization mode. The AGC target was MS:MS_COMMENTS set to 3e6, and the maximum IT was 200 ms. The mass resolution (full-width half MS:MS_COMMENTS maximum) was set to 70,000 @ m/z = 200. #MS_METABOLITE_DATA MS_METABOLITE_DATA:UNITS Peak Area MS_METABOLITE_DATA_START Samples Blank_batch2 Jej_Group1_931 Jej_Group1_932 Jej_Group1_933 Jej_Group1_934 Jej_Group1_935 Jej_Group2_937 Jej_Group2_938 Jej_Group2_939 Jej_Group2_7596 Jej_Group2_7597 Liver_Group1_931 Liver_Group1_932 Liver_Group1_933 Liver_Group1_934 Liver_Group1_935 Liver_Group2_937 Liver_Group2_938 Liver_Group2_939 Liver_Group2_7596 Liver_Group2_7597 Blank_batch1 Jej-13163 Jej-13166 Jej-13167 Jej-13170 Jej-13171 Jej-13172 KHK_Gly_2_000 KHK_Gly_2_010 KHK_Gly_2_030 KHK_Gly_2_060 KHK_Gly_2_120 KHK_Gly_3_000 KHK_Gly_3_010 KHK_Gly_3_030 KHK_Gly_3_060 KHK_Gly_3_120 KHK_Gly_6_000 KHK_Gly_6_010 KHK_Gly_6_030 KHK_Gly_6_060 KHK_Gly_6_120 KHK_Gly_1_000 KHK_Gly_1_010 KHK_Gly_1_030 KHK_Gly_1_060 KHK_Gly_1_120 KHK_Gly_4_000 KHK_Gly_4_010 KHK_Gly_4_030 KHK_Gly_4_060 KHK_Gly_4_120 KHK_Gly_5_000 KHK_Gly_5_010 KHK_Gly_5_030 KHK_Gly_5_060 KHK_Gly_5_120 Blank_batch9 Ms1_T0 Ms1_T15 Ms1_T45 Ms1_T90 Ms2_T0 Ms2_T15 Ms2_T45 Ms2_T90 Ms3_T0 Ms3_T15 Ms3_T45 Ms3_T90 Ms4_T0 Ms4_T15 Ms4_T45 Ms4_T90 Ms6_T0 Ms6_T30 Ms6_T60 Ms6_T120 Ms7_T0 Ms7_T30 Ms7_T60 Ms7_T120 Ms8_T0 Ms8_T30 Ms8_T60 Ms8_T120 Ms9_T0 Ms9_T30 Ms9_T60 Ms9_T120 Blank_batch10 Ms5_T0 Ms5_T15 Ms5_T45 Ms5_T90 Ms10_T0 Ms10_T30 Ms10_T60 Ms10_T120 Blank_batch8 H12071 H12091 H12092 H12093 H12094 H12095 L12086 L12096 L12097 L12098 L12099 L12100 Blank_batch6 Blank_batch11 13C-Fruc_HFD-HV_13163 13C-Fruc_HFD-HV_13164 13C-Fruc_HFD-HV_13165 13C-Fruc_HFD-HV_13166 13C-Fruc_HFD-HV_13167 13C-Fruc_HFD-PV_13163 13C-Fruc_HFD-PV_13164 13C-Fruc_HFD-PV_13165 13C-Fruc_HFD-PV_13166 13C-Fruc_HFD-PV_13167 13C-Fruc_LFD-HV_13168 13C-Fruc_LFD-HV_13169 13C-Fruc_LFD-HV_13170 13C-Fruc_LFD-HV_13171 13C-Fruc_LFD-HV_13172 13C-Fruc_LFD-PV_13168 13C-Fruc_LFD-PV_13169 13C-Fruc_LFD-PV_13170 13C-Fruc_LFD-PV_13171 13C-Fruc_LFD-PV_13172 Unlabeled_LC-HV_13634 Unlabeled_LC-HV_13635 Unlabeled_LC-HV_13637 Unlabeled_LC-HV_13642 Unlabeled_LC-HV_13646 Unlabeled_LC-HV_13683 Unlabeled_LF-HV_6348 Unlabeled_LF-HV_13626 Unlabeled_LF-HV_13627 Unlabeled_LF-HV_13628 Unlabeled_LF-HV_13631 Unlabeled_LH-HV_914 Unlabeled_LH-HV_916 Unlabeled_LH-HV_917 Unlabeled_LH-HV_10632 Unlabeled_LH-HV_10684 Blank_batch7 HV_931 HV_932 HV_933 HV_934 HV_935 HV_937 HV_938 HV_939 HV_7596 HV_7597 PV_934 PV_931 PV_932 PV_933 PV_935 PV_937 PV_938 PV_939 PV_7596 PV_7597 Blank_batch5 CON-HV_0_13156 CON-HV_0_13157 CON-HV_0_13158 CON-HV_90_12146 CON-HV_90_12147 CON-HV_90_12148 CON-HV_120_12156 CON-HV_120_12157 CON-HV_120_12158 CON-PV_0_13156 CON-PV_0_13157 CON-PV_0_13158 CON-PV_90_12146 CON-PV_90_12147 CON-PV_90_12148 CON-PV_120_12156 CON-PV_120_12157 CON-PV_120_12158 HFD-HV_0_13151 HFD-HV_0_13152 HFD-HV_0_13153 HFD-HV_90_12141 HFD-HV_90_12142 HFD-HV_90_12143 HFD-HV_120_12151 HFD-HV_120_12152 HFD-HV_120_12153 HFD-PV_0_13151 HFD-PV_0_13152 HFD-PV_0_13153 HFD-PV_90_12141 HFD-PV_90_12142 HFD-PV_90_12143 HFD-PV_120_12151 HFD-PV_120_12152 HFD-PV_120_12153 Blank_batch4 CON-HV_15_12106 CON-HV_15_12107 CON-HV_15_12108 CON-HV_15_12109 CON-HV_15_12110 CON-HV_30_12116 CON-HV_30_12117 CON-HV_30_12118 CON-HV_30_12119 CON-HV_30_12120 CON-PV_15_12106 CON-PV_15_12107 CON-PV_15_12108 CON-PV_15_12109 CON-PV_15_12110 CON-PV_30_12116 CON-PV_30_12117 CON-PV_30_12118 CON-PV_30_12119 CON-PV_30_12120 HFD-HV_15_12101 HFD-HV_15_12102 HFD-HV_15_12103 HFD-HV_15_12104 HFD-HV_15_12105 HFD-HV_30_12121 HFD-HV_30_12122 HFD-HV_30_12123 HFD-HV_30_12124 HFD-HV_30_12125 HFD-PV_15_12101 HFD-PV_15_12102 HFD-PV_15_12103 HFD-PV_15_12104 HFD-PV_15_12105 HFD-PV_30_12121 HFD-PV_30_12122 HFD-PV_30_12123 HFD-PV_30_12124 HFD-PV_30_12125 Blank_batch3 CON-HV_45_12126 CON-HV_45_12127 CON-HV_45_12128 CON-HV_45_12129 CON-HV_45_12130 CON-HV_60_12136 CON-HV_60_12137 CON-HV_60_12138 CON-HV_60_12139 CON-HV_60_12140 CON-PV_45_12126 CON-PV_45_12127 CON-PV_45_12128 CON-PV_45_12129 CON-PV_45_12130 CON-PV_60_12136 CON-PV_60_12137 CON-PV_60_12138 CON-PV_60_12139 CON-PV_60_12140 HFD-HV_45_12121 HFD-HV_45_12122 HFD-HV_45_12123 HFD-HV_45_12124 HFD-HV_45_12125 HFD-HV_60_12121 HFD-HV_60_12122 HFD-HV_60_12123 HFD-HV_60_12124 HFD-HV_60_12125 HFD-PV_45_12121 HFD-PV_45_12122 HFD-PV_45_12123 HFD-PV_45_12124 HFD-PV_45_12125 HFD-PV_60_12121 HFD-PV_60_12122 HFD-PV_60_12123 HFD-PV_60_12124 HFD-PV_60_12125 Factors Genotype:Blank | Diet:Blank | Diet Duration:Blank | Treatment:Blank | Tissue:Blank | Collection Time (minute):Blank | Drinking:Blank Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Jejunum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Jejunum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Jejunum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Jejunum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Jejunum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Jejunum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Jejunum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Jejunum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Jejunum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Jejunum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Liver | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Liver | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Liver | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Liver | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Liver | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Liver | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Liver | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Liver | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Liver | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Liver | Collection Time (minute):10 | Drinking:Water Genotype:Blank | Diet:Blank | Diet Duration:Blank | Treatment:Blank | Tissue:Blank | Collection Time (minute):Blank | Drinking:Blank Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Jejunum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Jejunum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Jejunum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Jejunum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Jejunum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Jejunum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):30 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):60 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):120 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):30 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):60 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):120 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):30 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):60 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):120 | Drinking:Water Genotype:KHK-c-KO | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Water Genotype:KHK-c-KO | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Genotype:KHK-c-KO | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):30 | Drinking:Water Genotype:KHK-c-KO | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):60 | Drinking:Water Genotype:KHK-c-KO | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):120 | Drinking:Water Genotype:KHK-c-KO | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Water Genotype:KHK-c-KO | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Genotype:KHK-c-KO | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):30 | Drinking:Water Genotype:KHK-c-KO | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):60 | Drinking:Water Genotype:KHK-c-KO | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):120 | Drinking:Water Genotype:KHK-c-KO | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Water Genotype:KHK-c-KO | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Genotype:KHK-c-KO | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):30 | Drinking:Water Genotype:KHK-c-KO | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):60 | Drinking:Water Genotype:KHK-c-KO | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):120 | Drinking:Water Genotype:Blank | Diet:Blank | Diet Duration:Blank | Treatment:Blank | Tissue:Blank | Collection Time (minute):Blank | Drinking:Blank Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):- | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):15 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):45 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):90 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):- | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):15 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):45 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):90 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):- | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):15 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):45 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):90 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):- | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):15 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):45 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):90 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):- | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):30 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):60 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):120 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):- | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):30 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):60 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):120 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):- | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):30 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):60 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):120 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):- | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):30 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):60 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):120 | Drinking:Water Genotype:Blank | Diet:Blank | Diet Duration:Blank | Treatment:Blank | Tissue:Blank | Collection Time (minute):Blank | Drinking:Blank Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):- | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):15 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):45 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):90 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):- | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):30 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):60 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Glycerate injection | Tissue:Tail Vein Serum | Collection Time (minute):120 | Drinking:Water Genotype:Blank | Diet:Blank | Diet Duration:Blank | Treatment:Blank | Tissue:Blank | Collection Time (minute):Blank | Drinking:Blank Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Fructose water Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Fructose water Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Fructose water Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Fructose water Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Fructose water Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Fructose water Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Fructose water Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Fructose water Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Fructose water Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Fructose water Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Fructose water Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Fructose water Genotype:Blank | Diet:Blank | Diet Duration:Blank | Treatment:Blank | Tissue:Blank | Collection Time (minute):Blank | Drinking:Blank Genotype:Blank | Diet:Blank | Diet Duration:Blank | Treatment:Blank | Tissue:Blank | Collection Time (minute):Blank | Drinking:Blank Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:12 weeks | Treatment:Saline injection | Tissue:Systemic Serum | Collection Time (minute):1440 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:12 weeks | Treatment:Saline injection | Tissue:Systemic Serum | Collection Time (minute):1440 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:12 weeks | Treatment:Saline injection | Tissue:Systemic Serum | Collection Time (minute):1440 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:12 weeks | Treatment:Saline injection | Tissue:Systemic Serum | Collection Time (minute):1440 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:12 weeks | Treatment:Saline injection | Tissue:Systemic Serum | Collection Time (minute):1440 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:12 weeks | Treatment:Saline injection | Tissue:Systemic Serum | Collection Time (minute):1440 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:12 weeks | Treatment:Fructose injection | Tissue:Systemic Serum | Collection Time (minute):1440 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:12 weeks | Treatment:Fructose injection | Tissue:Systemic Serum | Collection Time (minute):1440 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:12 weeks | Treatment:Fructose injection | Tissue:Systemic Serum | Collection Time (minute):1440 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:12 weeks | Treatment:Fructose injection | Tissue:Systemic Serum | Collection Time (minute):1440 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:12 weeks | Treatment:Fructose injection | Tissue:Systemic Serum | Collection Time (minute):1440 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:12 weeks | Treatment:Glycerate injection | Tissue:Systemic Serum | Collection Time (minute):1440 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:12 weeks | Treatment:Glycerate injection | Tissue:Systemic Serum | Collection Time (minute):1440 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:12 weeks | Treatment:Glycerate injection | Tissue:Systemic Serum | Collection Time (minute):1440 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:12 weeks | Treatment:Glycerate injection | Tissue:Systemic Serum | Collection Time (minute):1440 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:12 weeks | Treatment:Glycerate injection | Tissue:Systemic Serum | Collection Time (minute):1440 | Drinking:Water Genotype:Blank | Diet:Blank | Diet Duration:Blank | Treatment:Blank | Tissue:Blank | Collection Time (minute):Blank | Drinking:Blank Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:4 weeks | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):10 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:4 weeks | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):10 | Drinking:Water Genotype:Blank | Diet:Blank | Diet Duration:Blank | Treatment:Blank | Tissue:Blank | Collection Time (minute):Blank | Drinking:Blank Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):90 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):90 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):90 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):120 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):120 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):120 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):- | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):- | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):- | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):90 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):90 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):90 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):120 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):120 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):120 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):- | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):90 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):90 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):90 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):120 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):120 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):120 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):- | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):- | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):- | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):90 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):90 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):90 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):120 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):120 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):120 | Drinking:Water Genotype:Blank | Diet:Blank | Diet Duration:Blank | Treatment:Blank | Tissue:Blank | Collection Time (minute):Blank | Drinking:Blank Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):15 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):15 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):15 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):15 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):15 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):30 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):30 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):30 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):30 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):30 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):15 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):15 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):15 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):15 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):15 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):30 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):30 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):30 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):30 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):30 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):15 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):15 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):15 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):15 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):15 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):30 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):30 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):30 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):30 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):30 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):15 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):15 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):15 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):15 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):15 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):30 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):30 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):30 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):30 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):30 | Drinking:Water Genotype:Blank | Diet:Blank | Diet Duration:Blank | Treatment:Blank | Tissue:Blank | Collection Time (minute):Blank | Drinking:Blank Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):45 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):45 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):45 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):45 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):45 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):60 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):60 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):60 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):60 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):60 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):45 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):45 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):45 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):45 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):45 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):60 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):60 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):60 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):60 | Drinking:Water Genotype:Wild-type | Diet:CD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):60 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):45 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):45 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):45 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):45 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):45 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):60 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):60 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):60 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):60 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Systemic Serum | Collection Time (minute):60 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):45 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):45 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):45 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):45 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):45 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):60 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):60 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):60 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):60 | Drinking:Water Genotype:Wild-type | Diet:HFD | Diet Duration:3 days | Treatment:Control | Tissue:Portal Vein Serum | Collection Time (minute):60 | Drinking:Water Fructose_M0 0 560055.8065 506935.4003 1260053.167 917239.5841 1214660.443 386366.1711 464321.5028 165325.11 311633.7528 218955.458 190173.0086 263591.1114 260113.6725 371583.9359 283761.6196 73035.3174 142628.9392 80789.19466 128462.6799 130897.8963 30964.80907 162939.6243 513297.0357 255076.2927 729292.1162 230895.1119 175966.0681 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5932.76191 8499817.548 0 4300288.527 876604.1884 0 1710428.592 0 0 0 1168730.252 1116481.554 469316.922 3431.295901 8845.757776 949223.215 902049.9748 730430.8626 673735.6162 1132841.97 904458.9229 1038762.936 823647.7481 693409.4198 1071350.639 751009.8182 671732.4314 731206.1583 789067.589 796615.2442 850739.8081 691878.2076 767464.051 766334.526 797617.9334 968534.9386 757065.9736 717928.9145 774231.2825 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74789.50647 80212.28941 85239.00552 59633.40664 74294.1801 132330.0471 86753.59238 86801.26457 86675.96803 113791.8658 83475.06958 64322.24018 32672.4111 97611.42244 0 109235.7117 58007.12478 76026.53757 59962.38517 54353.06889 42443.11691 14256.11775 69799.29788 50796.07219 43339.9585 124899.7492 48072.01299 52369.2796 71276.60874 78051.10083 60243.51444 38508.82477 64590.39769 55801.1817 64521.06725 84926.19916 102125.2731 74354.65422 87354.74846 58946.55305 54035.82081 54092.06539 42548.64676 73597.47288 42895.18817 266946.6052 93533.94331 72963.23958 96941.59141 84541.98097 68853.90373 75714.90687 48744.94106 55482.08876 64064.78534 4528.105633 105330.7139 51437.61534 100582.7279 60176.25153 53851.18529 54899.23223 57957.77929 109324.4601 148300.4895 102258.1218 63363.04048 121905.8685 50836.36542 50749.32016 64408.46916 70301.16411 64756.23253 89086.67539 102093.0613 82056.13673 92594.64576 61574.69766 88837.94886 70317.42618 59312.68828 96772.04029 118311.1242 102270.4924 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2746464.519 8685564.55 1111845.799 3314058.868 4413616.313 2249214.827 4560447.927 2121128.337 3571605.054 6376945.071 747.2360321 90559694.91 124173294.1 103567318.8 114003814.1 43059058.77 90950975.94 0 860969.94 825570.81 265041.47 103416.88 0 71201.63093 35640.5085 16627.50206 1351.431276 0 51666.26 107528.28 280409.91 15873.25 0 140427 168945 111814 33526 0 221296 317090 242441 26183 0 207623 132248.2 67867.76 5893.79 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3879792.997 2483422.893 3231421.354 2676955.02 2526448.59 13179270.46 9412154.539 10387108.32 5145007.174 6762585.751 4095026.269 2961959.519 3557447.015 5537529.655 3414506.135 10595794.19 10565846.89 5409560.502 6569092.841 10606476.78 0 0 0 0 0 0 0 0 0 0 1551.248025 0 0 2337.894556 0 0 0 13031.23629 21255.53646 0 72903.74004 154331.5392 12480.2579 9146.757085 17789.59037 0 0 149669.9358 240238.8724 200665.8637 151888.5375 280625.573 121826.2198 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43206.20062 0 15752.5976 0 224633.46 0 0 16664.66719 0 0 0 0 0 0 0 67015.09191 215235.8134 344240.1485 532490.6247 0 60259.94711 227293.6886 440688.9795 490639.7188 0 25651.24193 124776.4843 234805.3869 368552.6796 0 20635.94334 0 334537.2871 409898.608 0 44208.75311 166810.5737 351113.3502 394533.9038 0 51717.86754 78535.21318 261099.4677 286278.2898 739.5289351 0 0 83819.40217 0 0 0 0 0 0 0 0 0 0 0 60469.25566 0 0 0 0 0 0 0 0 0 0 0 0 8818.736869 0 0 0 0 22508.39502 0 0 0 0 0 0 0 0 0 0 55570.59619 0 0 0 0 0 0 0 12273.7502 0 0 0 0 1222098.585 767586.3404 875884.2703 1469945.088 1025645.76 1059885.63 998916.9166 991551.3476 996338.2147 810921.3317 1093770.284 1172045.704 889882.4114 707788.99 1229118.648 822327.3575 680417.1623 583525.4437 596963.616 1015586.697 0 0 0 62666.97266 115351.9301 0 49168.36144 503833.3513 0 0 0 7883.517715 0 0 0 0 0 320277.7082 748513.514 498388.3693 506468.7954 0 0 0 0 0 0 674709.2212 625516.3452 88830.33717 375478.1772 0 0 0 0 0 0 21763.29857 0 0 0 6925958.585 8795407.536 7768632.349 5253894.24 5095403.551 6661913.286 0 0 0 8472577.38 15428847.6 6844388.98 5600914.302 5978646.942 6750602.488 0 0 0 6873755.131 8037386.406 7003564.967 7725477.455 6554551.394 6605536.885 0 0 0 6902308.213 11164313.05 8365203.281 6165113.791 3141188.333 6965579.724 0 1204016.007 1937501.831 975488.0543 1461772.56 1526895.515 4325749.624 1676663.97 3787932.033 4278299.241 2611487.549 1210181.634 1750412.664 1233383.021 1501245.494 1371010.757 6340267.486 3046333.789 3301455.352 4532728.53 3287658.172 1962089.76 2252143.589 2439666.807 2392904.641 1757831.69 4356120.828 3182208.94 5592450.669 4677208.709 4947248.906 2011238.312 1841442.612 1897006.508 2409000.739 1698266.171 4508151.149 3986602.377 5869627.996 4902469.495 5011205.674 0 8965970.323 10572996.87 9207877.362 7972718.3 5972033.149 8992836.64 6976993.671 11307224.42 13150573.35 11764908.97 7313802.534 11603956.3 6439544.975 6980984.911 5679989.684 8225237.751 7135011.452 11616820.21 11989878.4 10242268.62 9066732.652 7685801.178 10705845.8 9241652.328 9153558.616 10953882.11 11714611.09 10696767.96 14754744.19 9393651.875 6945477.784 6582185.787 10623820.82 9599830 9487844.127 11390954.4 9064587.972 10092217.64 13082090.99 8739594.567 Glucose_M2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5191.335069 0 0 0 0 0 0 0 0 0 0 0 48334.34681 202882.8426 352358.4455 0 0 137378.5994 265277.9287 191563.9759 0 0 18918.17986 162071.0817 269599.22 0 0 0 141593.7177 212253.4648 0 0 0 163494.286 219189.3873 0 0 0 75465.71977 113674.2532 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14288.66989 0 0 0 2922403.889 6945227.903 4708416.576 1211813.226 714392.6011 2720139.236 0 0 0 3653893.621 12110347.13 4628632.923 1478694.638 1279627.961 2865876.764 0 0 0 5413588.389 5129127.76 5639729.349 4385831.969 3381253.504 2820181.975 0 0 0 5694001.583 7354484.878 6709233.99 3479514.046 1539401.9 3011480.812 147.8190271 657642.8038 480613.787 0 72890.02341 0 2815926.131 1096799.237 1908687.497 3204099.013 1507245.205 579492.2369 384138.6632 0 75645.8412 0 3527015.422 2167325.268 1605263.39 3217951.898 2164349.827 402560.5468 276493.8581 550293.564 882443.3772 551382.2124 3246766.709 2119484.564 4985109.664 4385634.282 4103493.152 422672.4289 100761.3809 235790.4046 936484.2195 513165.2561 3481034.061 2546088.563 5167472.289 4376241.526 4074950.926 3839.441601 5180294.135 9033592.31 4355338.671 4344652.997 2651946.868 3657347.212 3462185.368 5931131.686 8416389.146 5867083.383 4343064.705 10005808.26 3754535.997 4288021.171 2405227.803 3900231.942 3693271.476 6712938.066 7840911.877 6037840.665 5595622.101 6003767.353 6793501.346 7934080.721 8329893.632 8349970.927 7294632.456 9693386.538 11947658.77 6942588.143 4549609.68 5153860.043 7149963.025 8337578.86 9249452.084 9436678.239 6531814.377 8852647.742 11288927.06 6219735.737 Glucose_M3 0 883349.0434 1041771.678 756132.197 1053869.303 583812.9594 388602.3432 272119.4545 710581.9268 467220.1996 161105.8457 1040754.981 1355866.914 930382.1006 1609775.872 985619.6631 711148.727 394808.1516 1373726.914 440111.9411 101158.4899 0 1023526.216 916102.4894 776427.4926 686967.3398 148128.5904 207181.7783 0 745425.3072 1510962.157 1417155.118 884192.6771 0 380323.5685 839662.845 778008.1605 279637.4722 0 140831.6168 727685.025 1056757.659 869208.9277 0 367611.112 58.27386766 1373171.386 905558.2609 0 475489.7871 1446585.303 1831412.99 794850.6339 0 614022.7927 714340.9435 1336643.427 364571.7754 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11043458.52 8888156.468 8830222.308 10274013.02 8863439.624 9667262.465 9637655.533 8975351.668 8369139.701 9073392.435 9255593.702 7155987.285 9033762.788 6141240.483 9602275.489 9444050.105 7302531.397 7577051.415 5778642.802 8737389.166 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8160912.269 9015070.516 7009426.843 10208260.78 7080045.11 2493030.158 2658457.506 6378881.899 2570289.981 469260.3573 8784400.734 8400626.209 7911958.931 7811630.737 6845409.833 3236071.541 2701422.083 6841477.548 2720448.522 327472.9968 83537.43904 0 0 0 5518261.347 15765320.55 12652368.84 3662212.385 1961897.929 6181640.688 0 0 0 6380182.56 25503448.85 11715411.56 4285596.204 2374625.233 5892335.438 0 0 0 15989779.11 14637302.01 17152717.62 12280922.97 7345298.049 9080434.428 0 0 0 16213329.98 20475986.18 20953495.68 9488202.431 3402129.251 8890778.262 0 11991076.06 10946817.81 6200007.139 9478978.054 9318578.498 15779139.64 5987310.483 13409370.32 16085980.56 11599907.8 12224050.01 11104610.8 6788311.624 11466548.9 9583821.864 22481629.96 11851972.79 13461197.37 16595495.69 16033832.97 12938696.44 11705196.28 14532833.71 13648712.48 11675962.69 21790061.89 14108866.48 24189921.36 19457044.68 25075290.96 13978681.2 11810417.86 12755995.38 14955606.39 12607517 22729836.39 17060462.26 23748987.38 20976221.96 26844769.8 0 25694267.36 34362167.53 22088385.55 26116026.75 18716109.42 14371418.66 20716572.97 16950985.85 19706101.6 19207086.76 22066706.14 37502659.61 16529485.18 24409682.01 19213889.6 14736895.25 22777677.42 18543683.08 18888668.16 17564909.36 32198847.77 32969836.26 29049365.03 34739244.73 35132893.26 27001457.5 23665712.24 33691071.42 40717258.18 27261418.34 27815435.57 30960506.32 30070306.91 37677605.58 41038491.08 29504358.73 20238854.68 32240247.93 37556078.29 26010827.58 Glucose_M4 0 88231.84204 141038.5239 67692.14916 94737.38977 58930.53613 38690.24309 17937.16803 70827.30405 58443.3718 14457.685 68975.17056 91487.31704 65347.32243 108813.4846 60888.51508 45326.24756 38005.32571 65384.7306 15986.28927 8877.920835 0 0 0 0 0 0 0 0 33238.21969 135927.4687 203282.8494 138535.3331 0 14811.87769 67884.70388 70508.53443 22092.51015 0 3333.02262 39824.4861 94653.70811 88141.85191 0 5638.942534 0 121839.975 88146.5804 0 5552.07009 77506.10559 167909.6282 82461.07394 0 6567.249898 22632.11437 67739.40207 15911.46946 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 25794.31728 0 20325.60918 29754.65354 30839.34121 0 7702.716201 17730.82839 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 641270.7322 376470.3554 516141.7493 625785.1932 526512.3968 678877.4696 586875.5041 625524.9244 518749.9561 540355.1453 553759.6402 440765.1423 417049.6265 306169.5151 470296.0025 731027.2958 518592.7913 421418.1839 293929.6352 504626.5922 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 421750.7967 430338.0519 454376.8699 681814.8403 353285.8007 123509.2352 146245.0732 237618.579 106038.3286 12103.59482 504412.5721 560808.016 431210.601 572881.0175 410262.6636 236521.1043 250661.2328 385855.2288 178004.8187 24908.18344 9463.128636 0 0 0 768136.9392 2463640.53 1804815.381 388120.9676 115488.3434 658642.7203 0 0 0 951862.8564 4595910.089 1682537.876 451581.1391 191290.6054 659870.998 0 0 0 2075355.347 1998178.051 2452025.587 1088581.276 625506.4191 969977.7095 0 0 0 2270514.533 3007042.296 3296166.466 816962.9975 295656.1853 924887.1044 0 962493.206 1054535.914 363297.0115 765721.5115 718102.5787 1711926.064 660205.1819 1278462.94 2160882.574 1380670.139 971559.9107 1072899.135 448966.3797 980971.6523 692115.8502 2683381.544 1440909.065 1432512.389 2214760.804 2004791.217 1132853.125 980570.4635 1268313.227 1086853.145 848737.8546 1955381.696 1570122.627 2739624.213 2401901.478 2373831.36 1352534.997 861173.7453 1189899.955 1309122.72 965543.9054 2152397.792 2083190.956 2779812.299 2793468.759 2577276.058 0 3702669.252 4493391.043 1966080.447 3215867.144 1360595.779 1843919.156 2068056.515 2534952.37 2763752.19 2598129.123 3170560.015 5206506.882 1463453.601 3275309.229 1491102.194 2027244.583 2578547.795 2840926.889 2673868.782 2498968.63 3396567.439 3073205.891 3595533.478 4368943.289 4205791.724 3616373.325 2962475.98 3900246.455 5282006.896 2250375.057 2692778.754 2851893.045 3722685.112 4710146.699 4802093.466 4107342.294 2711763.821 3836654.748 4788792.016 2339098.375 Glucose_M5 0 66781.61131 61529.41014 26740.21072 100171.2239 35295.66812 29437.69756 41562.58988 38431.94819 38480.3716 23703.25197 38191.1631 55727.57386 38672.83998 78846.33043 15757.56921 26814.55551 10757.57382 61287.99374 12790.24638 0 0 0 0 0 0 0 0 0 0 22609.5839 61439.86076 53314.64861 0 0 0 17607.01246 5859.768943 0 0 0 15038.04776 23187.41984 0 0 0 22991.28763 29470.51925 0 0 0 30787.79119 24660.21068 0 0 0 0 4040.76797 0 29595.70356 14683.12442 47452.61802 16441.29355 27357.81737 0 3409.133466 16851.41518 39428.89747 16262.76458 10308.5775 27898.76777 21829.33613 0 9279.065521 20377.93726 13286.18111 10201.89325 1794.462292 12355.95821 21469.63444 25821.7847 23166.33011 16353.21426 42996.30261 68798.32886 11282.30414 9051.745836 38433.13407 8293.954156 42186.19732 12839.90565 0 15461.95138 0 3365.652756 41235.12718 25898.85327 0 9622.340763 33454.9139 1581.592311 15082.30331 26493.65994 32646.88292 64771.34998 15653.28922 29187.43103 15771.67473 0 57058.9157 39970.26844 18564.36232 13761.59883 0 0 466885.3888 265938.5965 429530.6653 301013.6566 312492.2537 544571.419 366340.864 313546.6564 327609.7907 368438.0374 333490.7944 324603.8834 163707.2205 175698.8261 287117.107 396152.7566 330941.7096 216876.1846 148327.131 304870.2379 89002.3158 0 5676.710998 24073.22386 8668.015214 16450.23008 2163.229246 7404.706328 19675.16535 11338.85875 5891.789295 7444.483881 13286.08042 29030.44647 6037.511884 3864.561313 0 396624.8494 429697.6989 304634.3511 387438.6709 177482.3669 72650.39619 81859.76962 235904.5614 142298.342 18284.43994 395455.7726 506433.5925 274000.6294 317001.6916 279046.917 117428.5504 190178.7952 294024.8039 132689.1712 5967.589281 7065.715552 418186.6991 833523.541 173470.7813 510533.959 1685417.771 1152290.165 319623.3377 170576.1378 483209.2811 103243.1018 82745.70617 50299.24923 506031.444 2636742.504 1092990.009 228675.5109 119329.7867 445669.3666 71048.49666 85985.92842 115720.9637 1496968.979 1437596.825 1644658.285 696543.8184 426079.5867 614028.507 47572.12384 9260.43324 35879.63688 1597142.732 1666337.285 2205739.418 484144.5815 189127.1944 492672.8807 0 592879.8077 740285.2614 247471.8186 504475.0655 468921.1778 1308827.579 444772.1816 983849.4331 1777143.088 901680.4307 668001.6519 861919.4771 292054.6714 654477.1165 480769.7132 2001756.785 936689.5149 1081497.242 1673294.908 1526483.865 817618.4847 604853.5338 782787.4968 738809.1797 797147.0938 1586356.144 1362635.96 2045234.261 1872766.937 1691894.462 864573.2251 655227.2204 815484.3695 965399.1574 1549330.377 1734256.225 1537153.964 2241928.402 1952752.95 1834282.688 0 2373939.053 3365063.995 1326807.249 1751514.115 640411.1009 1125141.267 1302968.816 1515269.245 1836368.966 1602483.732 2043812.687 3775809.088 894919.027 1868812.859 756079.7304 1210009.506 1362305.053 1721358.165 1738204.776 1531459.134 2041247.525 2305162.496 2479928.003 2843985.111 3096155.954 2641297.691 2013615.213 2845764.582 3581025.138 1478053.184 1869892.568 2079261.109 2391581.808 3674868.748 3947358.449 2948128.595 1729427.417 2818840.28 3544779.665 1588254.862 Glucose_M6 0 1158795.489 1635598.05 715019.6213 1286533.965 963248.2873 966619.5819 557865.1512 1558159.448 1187505.009 320928.7886 484010.7002 774828.938 438496.9831 751567.364 439820.8886 537544.6544 405684.3421 642055.8043 327750.9608 166407.2081 0 0 0 0 0 0 0 0 210070.6813 770232.0063 742653.3339 200265.1324 0 146663.743 480709.1844 310636.8139 57942.69564 0 23876.90765 303856.7868 522959.6131 362611.7833 0 69569.72959 200520.3749 300408.0074 120324.3707 0 85398.72999 400789.4785 553875.699 122628.2338 0 119664.7855 176564.3149 248758.269 30969.50856 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5705827.904 4564680.193 4900451.335 5826566.229 5372952.029 7104939.801 7622889.579 7730158.459 6774517.936 7162122.369 4624850.527 3553444.52 3461533.53 3119036.408 3848439.203 6561045.796 5036372.456 3563498.17 3328544.668 4411888.433 5363.473828 9051.86574 0 8523.518462 0 0 0 0 6198.134112 3641.492903 0 0 0 0 0 0 0 4227586.684 4325284.832 3340000.263 4603487.014 4234026.153 1726813.225 2075330.179 2674816.978 1743728.452 423245.8581 5076443.42 5910180.631 5632275.561 4733169.971 4839855.119 3398554.756 3145917.282 5119181.756 2945855.6 653712.6302 54599.29059 40204.01378 76035.05808 23377.52866 2560603.655 7805033.453 6303956.461 1055972.814 324068.9813 1626272.305 36301.17762 30191.7432 9238.801044 2924917.883 14202858.13 6447651.41 1118241.132 397678.0554 1571823.268 22042.41068 15595.11731 15596.35785 8774362.513 7937908.02 10717816.82 3514391.098 1921171.566 3277910.12 9468.14381 10899.17033 8435.479401 9420710.375 11388267.36 13632779.1 2766652.285 901162.1118 3299291.309 0 8754105.944 7778164.444 3361640.046 5480640.196 5191204.784 9928394.367 3942232.323 8205136.734 10998494.84 7553776.763 9343482.77 10834963.45 4534887.733 8088837.166 6715595.09 15485828.63 9578279.548 8675943.403 12127373.3 11445175.79 8464754.47 8800728.339 10667732.86 8270009.427 7378382.663 11658528.1 11806492.08 14194246.58 14557299.16 12476519.71 11160351.09 9181031.783 11215027.14 11180430.15 9515214.566 13716119.63 16056379.48 15116931 17504954.98 15046748.27 0 18506502.85 20998101.28 9671429.663 17411838.44 8932736.908 7946665.348 12430040.7 9629726.103 9402026.48 8146121.969 16720374.96 25182044.74 7994857.723 20065514.3 11718315.43 8323666.793 14640868.58 11018030.98 9209410.459 7836689.386 21598814.28 18250998.83 16281387.45 21831491.46 23698462.77 15815343.44 11726865.19 16396150.27 21282227.31 10959793.91 20853299.52 20284168.5 17135913.48 24238255.74 28811124.32 17807649.04 10095104.92 17906583.14 20310642.88 10933672.3 Glycerate_M0 10913.11812 4171550.659 4024788.032 3995400.012 2948683.497 3415241.805 3285556.844 6065025.758 2230472.42 2237876.483 3102343.847 816634.4654 749033.5842 780736.5266 739308.8286 692285.1956 512977.0075 719837.3345 446430.6319 654362.5118 995249.0508 0 4114816.063 11461978.85 7808303.628 5180369.085 13959840.42 5547945.774 64776.04863 146381.853 113851.1049 74147.13552 39986.49294 14469.83593 26118.28127 25422.93722 27500.47536 40592.87206 14810.65391 71028.5883 46634.97632 46257.75831 26649.59893 74448.85844 71617.93601 34908.54908 100971.4466 63332.86371 73179.82305 104993.1096 93625.26991 58171.99739 36419.28911 68993.21806 99453.56793 21050.86194 38119.73285 46601.8698 116126.0303 7786704.22 297654193.9 222647892.9 118996772 3239319.563 685732081.3 533187545.3 153287034 5257856.777 301506291.8 253818101.5 202194152.4 5020685.59 326859591.9 199027936.9 175396561.8 4963639.285 605301827 409134293.9 77202741.61 4729675.064 92963322.98 83823228.72 140080982.2 7905413.793 25991366.45 94785251.46 100599697.7 5385430.303 300294852.6 210831992.8 139874526.9 0 4271346.604 826484614.1 662617653.2 269573367.8 3129240.765 610695190.6 358777783.9 52089532.24 0 2541172.958 2756108.34 4047875.235 4650053.945 3004462.186 4346037.017 3107522.144 2448099.782 2787183.349 2802710.736 1920787.756 2714375.291 20279.25715 13454.73172 293419.0068 243057.8723 365915.247 327454.2939 247609.3092 487102.9404 396258.7673 492393.2081 858951.8145 349833.449 343135.0672 329357.627 386806.1679 591990.4292 316968.4729 702290.0863 539697.5114 386161.0531 303335.9329 496063.0655 1297977.545 218989.0617 584249.509 761722.0443 806481.4995 1081435.074 416043.152 508855.953 519022.4278 641638.7854 330289.5229 237888.14 913927.8729 751559.0275 216333.603 627986.3779 0 2047953.049 3230599.825 2331704.302 1542756.643 3129716.832 2931564.2 1860366.233 3305523.084 2878386.565 1569404.658 3810719.56 3780900.738 2541416.794 4071986.54 2720834.436 3066765.317 2337151.837 2999424.365 2191362.449 1806698.759 4706.811605 2553200.81 3814387.037 1677423.203 2759097.673 1878016.984 2114849.873 2396320.975 2069392.115 2266223.8 2207457.077 3904992.148 1964737.783 1960845.001 1554588.631 1823593.539 1760398.712 1256749.625 1633794.752 2555929.625 2240725.088 2880275.922 2867900.184 3316415.16 1360784.088 2064594.477 1861274.968 2050051.457 3607560.708 2960594.117 2252344.342 2052140.199 1506092.822 2045539.167 1787062.471 363852.7341 2817132.819 5793.53053 1699990.568 2244337.98 2207076.287 1493530.414 2542484.524 1768406.447 231969.2853 1879778.653 2658287.747 3505969.044 2789227.229 2766904.042 2341118.898 3089325.968 1740807.48 1584849.975 1672169.479 2327020.483 1469447.39 3412908.571 2487411.644 3057150.479 1827610.735 1810477.356 1915644.782 2030437.082 2336473.491 2302425.263 2066647.384 1386866.985 2455789.109 4546783.164 2097718.078 2772135.85 7464487.058 2688883.324 3941831.426 1756149.415 2268702.157 1943971.021 59308.12581 2917911.57 2861022.597 3450106.505 3100756.957 2485500.618 2285882.639 2501368.641 2362544.499 2446445.729 2473565.439 3167646.293 7566741.358 1266122.741 2454990.029 3252018.189 4375147.478 2903182.217 3478403.533 3334116.712 2666206.459 3388354.588 2622291.283 3031704.612 3231887.318 2627597.738 1230133.932 1996786.016 2356502.659 2635600.373 1602545.745 3623078.703 3438680.781 3812160.414 4014138.087 6524416.256 2799538.067 1770963.5 3479536.612 5041627.673 1862925.177 Glycerate_M1 0 42705.2428 51448.45927 30498.94793 40499.66814 23213.51622 11356.30327 32785.45593 34673.88618 14631.00833 4008.820322 0 0 5393.689393 0 0 0 0 0 0 0 1654.515184 38081.55345 73679.14042 12797.10781 21874.64171 102283.6179 21512.48299 0 0 812.104875 1619.326259 963.190293 0 16.62038659 135.6705054 448.4256256 483.043977 0 0 0 0 716.6853891 0 141.0913883 0 0 1223.323442 0 0 0 522.3220153 189.232748 0 0 0 0 1740.570062 7875.841204 0 78591.07103 0 0 0 470695.9364 437838.8523 28737.83792 0 156776.0877 0 36079.84327 2451.87233 49959.44766 195170.4376 0 0 431672.6002 0 122311.3567 0 0 0 165119.3182 0 0 0 0 0 0 77664.09338 0 0 0 157861.3641 1022277.539 0 0 480228.1605 313719.5554 0 11643.61393 0 7735.486041 0 0 0 0 0 0 0 0 0 0 382.5888184 580.5171818 2022.180416 1397.779777 0 877.3681979 1586.922574 5081.202222 0 1495.48871 835.557398 560.8809147 514.7190924 1972.299383 1198.388303 0 1732.02164 2185.924695 0 0 0 587.7175148 0 1668.33863 0 4296.433875 0 0 529.8329845 0 2585.170415 1008.337311 0 0 0 0 0 0 3119.283805 2831.655484 0 1017.398594 0 0 8316.538617 37433.69017 0 0 0 2047.136512 2653.029609 0 38651.65156 11268.67928 0 0 2507.986791 0 0 0 0 0 0 67911.95716 52087.26856 50835.2968 29782.27786 35719.71671 36513.65905 0 0 1324.00484 32258.71505 32112.91632 40503.87601 17678.94344 27507.66553 51752.56357 0 0 0 36225.65882 51284.89781 34833.0889 66415.81538 12895.42358 43570.50612 0 0 5774.70148 14359.2755 37924.44078 17912.33428 28225.10801 3304.487675 22038.59337 0 21979.19826 0 22309.03374 7420.910175 18052.21796 12880.24078 1963.179669 22072.39517 38762.46833 31567.05472 1489.568675 0 440.5273916 9750.853576 0 20241.20961 0 6276.650379 7472.572453 29892.49039 25791.98997 0 11778.68583 5083.934733 10972.14768 24387.36142 23027.78717 19287.80079 19391.29092 22295.36411 710.9020994 0 7989.932145 0 0 25508.95826 5741.796813 8338.321646 34446.39457 26165.64295 84.30570083 45819.4526 42682.11723 21256.94081 30221.51952 13992.28167 34973.09048 25800.38564 40492.30561 37954.99921 37395.18846 19912.53064 60425.07244 2745.622878 18543.84454 0 61778.71855 16627.46271 62912.67904 32360.44207 45583.69743 19748.57385 8848.193919 35672.36553 27658.08471 15433.25135 21365.85651 31519.21977 25530.00619 29948.07394 18774.70151 29814.59364 10492.40022 22992.73469 25248.40132 34624.96496 39946.31685 4367.516899 17250.91629 36263.45621 21401.16803 Glycerate_M2 0 35293.04014 66750.30411 46858.98054 21623.10728 28622.28828 34714.63933 24169.31833 30547.78042 19556.42859 14158.76425 0 0 0 0 0 0 0 0 0 0 0 0 75476.81663 25532.62191 23653.6868 64756.29857 25226.28549 0 0 0 1194.218243 1692.734041 0 0 0 0 105.9389871 0 0 0 0 0 0 0 0 636.5602733 638.8490298 0 0 540.7801341 0 0 0 0 0 0 585.2781476 0 0 0 5618.957256 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4473.406581 0 0 0 0 0 0 0 0 2061.434553 0 0 0 0 0 0 0 0 0 0 0 0 20300.66811 35939.94771 26849.76333 16618.34505 8311.850606 25162.61073 0 0 0 29255.75148 20673.69157 21728.65626 24885.21638 5934.180431 7116.983097 0 0 0 28523.09502 42631.87136 0 27572.92156 32043.68868 25493.86789 0 0 0 8432.856472 28661.74402 26427.79829 5415.707714 0 21090.77641 0 8586.669374 7130.112272 4016.28527 8900.929678 6377.646221 14568.62011 0 8984.052808 29589.76142 21858.80216 6987.843501 11411.57242 5472.646717 18637.6669 11568.86729 0 4948.187759 8798.299125 14004.37952 11697.3253 0 7634.511093 17881.63222 3135.065432 5023.183581 3450.84582 3125.014383 22681.84967 0 4537.898893 6667.367811 0 0 0 3177.313689 31119.20127 0 0 22856.25635 16890.79868 0 32543.59127 32729.1405 24898.36386 25412.39449 859.4821556 27862.39718 15733.21158 21827.11624 28004.90891 37620.89218 25495.04214 62641.32378 5753.474049 11643.71403 12639.26769 24476.67247 21483.22086 35386.59882 35300.29133 31788.83245 6920.606498 15687.83104 23179.75929 24465.22671 15990.62321 18542.4864 20625.82416 21923.76169 31439.16155 16174.33169 4486.067437 15548.75698 21311.85453 25899.1615 34342.83187 31358.19391 17445.66178 25424.92683 26984.79624 18621.65032 Glycerate_M3 0 4091702.354 4570052.441 2331819.79 3671512.651 2674100.87 1785587.543 1663475.451 1601456.189 1083856.118 746477.4095 0 0 0 0 0 0 3251.930921 0 0 0 0 7892935.909 5878692.543 5318590.103 3166619.02 2336894.459 1034240.431 0 9228.760223 24202.65641 21701.19934 12038.42648 0 2461.282652 20035.36572 14547.36806 1741.59534 0 665.4695459 10480.54268 25127.67939 7173.735768 0 364.6269683 1412.430565 2433.301723 3672.14251 0 397.6504002 5853.30477 6893.424919 4398.213928 0 319.7264971 0 1790.136916 1592.246504 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 25565.87451 13898.26792 18901.77789 19146.48983 21203.36224 52083.7142 50230.31984 34903.4035 40810.01936 31696.02184 12405.4892 13517.92764 15486.27753 16405.88981 10321.50815 31451.16968 29131.54287 16351.8023 14436.26841 16153.33207 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10003.40613 116744.4931 11744.89228 75260.15984 72139.14386 0 0 0 0 0 80423.17418 111694.7739 128323.0228 119331.4934 122679.763 0 0 24390.78081 0 0 0 0 0 0 79724.66245 159796.6033 123137.6405 34264.64604 27219.85247 67844.99022 0 0 0 57271.69767 159138.5405 142690.8927 67098.29151 26408.29329 43171.2622 0 0 0 191786.774 313527.5699 336737.774 171478.8844 91064.07155 67706.23748 0 0 0 169442.2522 195059.006 548353.3128 189664.7429 16443.74957 69348.16615 0 366136.461 319498.5701 72529.23623 222405.0078 209275.0535 513442.3209 32527.196 315406.0562 466747.4927 507063.4411 324464.5673 373594.9721 96375.33492 309163.5178 234664.3956 425524.5006 284955.5218 266232.5266 576609.9344 677328.7415 891645.3845 657840.2244 1125482.985 301614.0128 381383.3092 582360.6753 1180915.066 2592676.156 3588020.035 690561.6303 1523588.615 537193.8337 1180081.745 488678.4356 793651.8933 1043741.453 2053105.915 3443923.576 5817260.25 996194.1666 1678.144664 284955.8006 306995.0036 188561.3898 292489.149 78229.67743 150830.6923 214028.9854 162468.6164 159707.2163 143811.5677 199421.8967 564331.6805 82135.63544 301060.6092 130959.1595 217886.8908 284893.2968 219748.1312 150953.0667 141631.7187 287396.4223 381875.6964 239822.4215 344259.7159 337477.2324 172873.2997 158738.8382 343807.2883 633121.724 213051.7013 289708.6218 411498.5196 237912.0095 427722.3431 828700.9449 362645.3985 112143.8632 498010.1637 921574.1706 265062.3601 MS_METABOLITE_DATA_END #METABOLITES METABOLITES_START metabolite_name Compound Label Fructose_M0 Fructose 0 Fructose_M1 Fructose 1 Fructose_M2 Fructose 2 Fructose_M3 Fructose 3 Fructose_M4 Fructose 4 Fructose_M5 Fructose 5 Fructose_M6 Fructose 6 Glucose_M0 Glucose 0 Glucose_M1 Glucose 1 Glucose_M2 Glucose 2 Glucose_M3 Glucose 3 Glucose_M4 Glucose 4 Glucose_M5 Glucose 5 Glucose_M6 Glucose 6 Glycerate_M0 Glycerate 0 Glycerate_M1 Glycerate 1 Glycerate_M2 Glycerate 2 Glycerate_M3 Glycerate 3 METABOLITES_END #END