#METABOLOMICS WORKBENCH NicholasDevanney_20221114_111956 DATATRACK_ID:3571 STUDY_ID:ST002453 ANALYSIS_ID:AN004002 PROJECT_ID:PR001580
VERSION             	1
CREATED_ON             	January 20, 2023, 4:51 pm
#PROJECT
PR:PROJECT_TITLE                 	APOE modulates microglial immunometabolism in response to age, amyloid
PR:PROJECT_TITLE                 	pathology, and inflammatory challenge
PR:PROJECT_SUMMARY               	The E4 allele of Apolipoprotein E (APOE) is associated with both metabolic
PR:PROJECT_SUMMARY               	dysfunction and a heightened pro-inflammatory response – two findings that may
PR:PROJECT_SUMMARY               	be intrinsically linked through the concept of immunometabolism. Here, we
PR:PROJECT_SUMMARY               	combined bulk, single-cell, and spatial transcriptomics with cell-specific and
PR:PROJECT_SUMMARY               	spatially resolved metabolic analyses to systematically address the role of APOE
PR:PROJECT_SUMMARY               	across age, neuroinflammation, and AD pathology. RNAseq highlighted
PR:PROJECT_SUMMARY               	immunometabolic changes across the APOE4 glial transcriptome, specifically in
PR:PROJECT_SUMMARY               	subsets of metabolically distinct microglia enriched in the E4 brain during
PR:PROJECT_SUMMARY               	aging or following an inflammatory challenge. E4 microglia display increased
PR:PROJECT_SUMMARY               	Hif1α expression, a disrupted TCA cycle, and are inherently pro-glycolytic,
PR:PROJECT_SUMMARY               	while spatial transcriptomics and MALDI mass spectrometry imaging highlight an
PR:PROJECT_SUMMARY               	E4-specific response to amyloid that is characterized by widespread alterations
PR:PROJECT_SUMMARY               	in lipid metabolism. Taken together, our findings emphasize a central role for
PR:PROJECT_SUMMARY               	APOE in regulating microglial immunometabolism.
PR:INSTITUTE                     	University of Kentucky
PR:DEPARTMENT                    	Physiology
PR:LABORATORY                    	Lance Johnson; Josh Morganti
PR:LAST_NAME                     	Devanney
PR:FIRST_NAME                    	Nicholas
PR:ADDRESS                       	Physiology, 760 Press Ave, Healthy Kentucky Research Bldg, Rm152, Lexington,
PR:ADDRESS                       	Kentucky, 40508, USA
PR:EMAIL                         	Nicholas.Devanney@uky.edu
PR:PHONE                         	8593238083
PR:PROJECT_COMMENTS              	Part 3 of 3
#STUDY
ST:STUDY_TITLE                   	APOE modulates microglial immunometabolism in response to age, amyloid
ST:STUDY_TITLE                   	pathology, and inflammatory challenge (Part 3 of 3)
ST:STUDY_SUMMARY                 	The E4 allele of Apolipoprotein E (APOE) is associated with both metabolic
ST:STUDY_SUMMARY                 	dysfunction and a heightened pro-inflammatory response – two findings that may
ST:STUDY_SUMMARY                 	be intrinsically linked through the concept of immunometabolism. Here, we
ST:STUDY_SUMMARY                 	combined bulk, single-cell, and spatial transcriptomics with cell-specific and
ST:STUDY_SUMMARY                 	spatially resolved metabolic analyses to systematically address the role of APOE
ST:STUDY_SUMMARY                 	across age, neuroinflammation, and AD pathology. RNAseq highlighted
ST:STUDY_SUMMARY                 	immunometabolic changes across the APOE4 glial transcriptome, specifically in
ST:STUDY_SUMMARY                 	subsets of metabolically distinct microglia enriched in the E4 brain during
ST:STUDY_SUMMARY                 	aging or following an inflammatory challenge. E4 microglia display increased
ST:STUDY_SUMMARY                 	Hif1α expression, a disrupted TCA cycle, and are inherently pro-glycolytic,
ST:STUDY_SUMMARY                 	while spatial transcriptomics and MALDI mass spectrometry imaging highlight an
ST:STUDY_SUMMARY                 	E4-specific response to amyloid that is characterized by widespread alterations
ST:STUDY_SUMMARY                 	in lipid metabolism. Taken together, our findings emphasize a central role for
ST:STUDY_SUMMARY                 	APOE in regulating microglial immunometabolism.
ST:INSTITUTE                     	University of Kentucky
ST:DEPARTMENT                    	Physiology
ST:LABORATORY                    	Lance Johnson; Josh Morganti
ST:LAST_NAME                     	Devanney
ST:FIRST_NAME                    	Nicholas
ST:ADDRESS                       	Physiology, 760 Press Ave, Healthy Kentucky Research Bldg, Rm152, Lexington,
ST:ADDRESS                       	Kentucky, 40508, USA
ST:EMAIL                         	Nicholas.Devanney@uky.edu
ST:PHONE                         	8593238083
#SUBJECT
SU:SUBJECT_TYPE                  	Mammal
SU:SUBJECT_SPECIES               	Mus musculus
SU:TAXONOMY_ID                   	10090
SU:GENOTYPE_STRAIN               	APOE-targeted replacement mice homozygous for human E3
SU:GENOTYPE_STRAIN               	(B6.129P2-Apoe^tm2(APOE*3)Mae N8, Taconic #1548-F) or human E4 (B6.129P2-
SU:GENOTYPE_STRAIN               	Apoe^tm3(APOE*4)Mae N8, Taconic #1549-F) alleles and crossed to the 5x Familial
SU:GENOTYPE_STRAIN               	Alzheimer's Disease (5XFAD) model (MMRRC #34840, B6SJL^Tg(
SU:GENOTYPE_STRAIN               	APPSwFlLon,PSEN1*M146L*L286V)6799Vas/Mmjax))
SU:AGE_OR_AGE_RANGE              	3 months, 12 months, 24 months
SU:GENDER                        	Female
#FACTORS
#SUBJECT_SAMPLE_FACTORS:         	SUBJECT(optional)[tab]SAMPLE[tab]FACTORS(NAME:VALUE pairs separated by |)[tab]Raw file names and additional sample data
SUBJECT_SAMPLE_FACTORS           	B647	B647_Hippocampus	Brain Region:Hippocampus | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=4 of 4; Number of pixels in region of interest=249; RAW_FILE_NAME=1A MALDI lipids B647 B648 C761 B427 20210512.raw
SUBJECT_SAMPLE_FACTORS           	B647	B647_Fiber Tracts	Brain Region:Fiber Tracts | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=4 of 4; Number of pixels in region of interest=222; RAW_FILE_NAME=1A MALDI lipids B647 B648 C761 B427 20210512.raw
SUBJECT_SAMPLE_FACTORS           	B647	B647_Iso Cortex	Brain Region:Iso Cortex | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=4 of 4; Number of pixels in region of interest=634; RAW_FILE_NAME=1A MALDI lipids B647 B648 C761 B427 20210512.raw
SUBJECT_SAMPLE_FACTORS           	B647	B647_Olfact. Area	Brain Region:Olfact. Area | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=4 of 4; Number of pixels in region of interest=111; RAW_FILE_NAME=1A MALDI lipids B647 B648 C761 B427 20210512.raw
SUBJECT_SAMPLE_FACTORS           	B647	B647_Cortical Subplate	Brain Region:Cortical Subplate | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=4 of 4; Number of pixels in region of interest=47; RAW_FILE_NAME=1A MALDI lipids B647 B648 C761 B427 20210512.raw
SUBJECT_SAMPLE_FACTORS           	B647	B647_Cerebral Nuclei	Brain Region:Cerebral Nuclei | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=4 of 4; Number of pixels in region of interest=135; RAW_FILE_NAME=1A MALDI lipids B647 B648 C761 B427 20210512.raw
SUBJECT_SAMPLE_FACTORS           	B647	B647_Hypothalamus	Brain Region:Hypothalamus | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=4 of 4; Number of pixels in region of interest=356; RAW_FILE_NAME=1A MALDI lipids B647 B648 C761 B427 20210512.raw
SUBJECT_SAMPLE_FACTORS           	B647	B647_Thalamus	Brain Region:Thalamus | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=4 of 4; Number of pixels in region of interest=508; RAW_FILE_NAME=1A MALDI lipids B647 B648 C761 B427 20210512.raw
SUBJECT_SAMPLE_FACTORS           	B647	B647_TOTAL	Brain Region:TOTAL | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=4 of 4; Number of pixels in region of interest=2262; RAW_FILE_NAME=1A MALDI lipids B647 B648 C761 B427 20210512.raw
SUBJECT_SAMPLE_FACTORS           	B648	B648_Hippocampus	Brain Region:Hippocampus | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=3 of 4; Number of pixels in region of interest=189; RAW_FILE_NAME=1A MALDI lipids B647 B648 C761 B427 20210512.raw
SUBJECT_SAMPLE_FACTORS           	B648	B648_Fiber Tracts	Brain Region:Fiber Tracts | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=3 of 4; Number of pixels in region of interest=217; RAW_FILE_NAME=1A MALDI lipids B647 B648 C761 B427 20210512.raw
SUBJECT_SAMPLE_FACTORS           	B648	B648_Iso Cortex	Brain Region:Iso Cortex | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=3 of 4; Number of pixels in region of interest=680; RAW_FILE_NAME=1A MALDI lipids B647 B648 C761 B427 20210512.raw
SUBJECT_SAMPLE_FACTORS           	B648	B648_Olfact. Area	Brain Region:Olfact. Area | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=3 of 4; Number of pixels in region of interest=96; RAW_FILE_NAME=1A MALDI lipids B647 B648 C761 B427 20210512.raw
SUBJECT_SAMPLE_FACTORS           	B648	B648_Cortical Subplate	Brain Region:Cortical Subplate | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=3 of 4; Number of pixels in region of interest=47; RAW_FILE_NAME=1A MALDI lipids B647 B648 C761 B427 20210512.raw
SUBJECT_SAMPLE_FACTORS           	B648	B648_Cerebral Nuclei	Brain Region:Cerebral Nuclei | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=3 of 4; Number of pixels in region of interest=168; RAW_FILE_NAME=1A MALDI lipids B647 B648 C761 B427 20210512.raw
SUBJECT_SAMPLE_FACTORS           	B648	B648_Hypothalamus	Brain Region:Hypothalamus | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=3 of 4; Number of pixels in region of interest=323; RAW_FILE_NAME=1A MALDI lipids B647 B648 C761 B427 20210512.raw
SUBJECT_SAMPLE_FACTORS           	B648	B648_Thalamus	Brain Region:Thalamus | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=3 of 4; Number of pixels in region of interest=406; RAW_FILE_NAME=1A MALDI lipids B647 B648 C761 B427 20210512.raw
SUBJECT_SAMPLE_FACTORS           	B648	B648_TOTAL	Brain Region:TOTAL | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=3 of 4; Number of pixels in region of interest=2126; RAW_FILE_NAME=1A MALDI lipids B647 B648 C761 B427 20210512.raw
SUBJECT_SAMPLE_FACTORS           	B652	B652_Hippocampus	Brain Region:Hippocampus | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=4 of 4; Number of pixels in region of interest=249; RAW_FILE_NAME=2A MALDI lipids B652 C762 C763 C202 20210513.raw
SUBJECT_SAMPLE_FACTORS           	B652	B652_Fiber Tracts	Brain Region:Fiber Tracts | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=4 of 4; Number of pixels in region of interest=190; RAW_FILE_NAME=2A MALDI lipids B652 C762 C763 C202 20210513.raw
SUBJECT_SAMPLE_FACTORS           	B652	B652_Iso Cortex	Brain Region:Iso Cortex | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=4 of 4; Number of pixels in region of interest=686; RAW_FILE_NAME=2A MALDI lipids B652 C762 C763 C202 20210513.raw
SUBJECT_SAMPLE_FACTORS           	B652	B652_Olfact. Area	Brain Region:Olfact. Area | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=4 of 4; Number of pixels in region of interest=129; RAW_FILE_NAME=2A MALDI lipids B652 C762 C763 C202 20210513.raw
SUBJECT_SAMPLE_FACTORS           	B652	B652_Cortical Subplate	Brain Region:Cortical Subplate | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=4 of 4; Number of pixels in region of interest=62; RAW_FILE_NAME=2A MALDI lipids B652 C762 C763 C202 20210513.raw
SUBJECT_SAMPLE_FACTORS           	B652	B652_Cerebral Nuclei	Brain Region:Cerebral Nuclei | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=4 of 4; Number of pixels in region of interest=132; RAW_FILE_NAME=2A MALDI lipids B652 C762 C763 C202 20210513.raw
SUBJECT_SAMPLE_FACTORS           	B652	B652_Hypothalamus	Brain Region:Hypothalamus | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=4 of 4; Number of pixels in region of interest=276; RAW_FILE_NAME=2A MALDI lipids B652 C762 C763 C202 20210513.raw
SUBJECT_SAMPLE_FACTORS           	B652	B652_Thalamus	Brain Region:Thalamus | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=4 of 4; Number of pixels in region of interest=523; RAW_FILE_NAME=2A MALDI lipids B652 C762 C763 C202 20210513.raw
SUBJECT_SAMPLE_FACTORS           	B652	B652_TOTAL	Brain Region:TOTAL | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=4 of 4; Number of pixels in region of interest=2247; RAW_FILE_NAME=2A MALDI lipids B652 C762 C763 C202 20210513.raw
SUBJECT_SAMPLE_FACTORS           	C761	C761_Hippocampus	Brain Region:Hippocampus | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 4; Number of pixels in region of interest=252; RAW_FILE_NAME=1A MALDI lipids B647 B648 C761 B427 20210512.raw
SUBJECT_SAMPLE_FACTORS           	C761	C761_Fiber Tracts	Brain Region:Fiber Tracts | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 4; Number of pixels in region of interest=213; RAW_FILE_NAME=1A MALDI lipids B647 B648 C761 B427 20210512.raw
SUBJECT_SAMPLE_FACTORS           	C761	C761_Iso Cortex	Brain Region:Iso Cortex | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 4; Number of pixels in region of interest=707; RAW_FILE_NAME=1A MALDI lipids B647 B648 C761 B427 20210512.raw
SUBJECT_SAMPLE_FACTORS           	C761	C761_Olfact. Area	Brain Region:Olfact. Area | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 4; Number of pixels in region of interest=132; RAW_FILE_NAME=1A MALDI lipids B647 B648 C761 B427 20210512.raw
SUBJECT_SAMPLE_FACTORS           	C761	C761_Cortical Subplate	Brain Region:Cortical Subplate | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 4; Number of pixels in region of interest=75; RAW_FILE_NAME=1A MALDI lipids B647 B648 C761 B427 20210512.raw
SUBJECT_SAMPLE_FACTORS           	C761	C761_Cerebral Nuclei	Brain Region:Cerebral Nuclei | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 4; Number of pixels in region of interest=134; RAW_FILE_NAME=1A MALDI lipids B647 B648 C761 B427 20210512.raw
SUBJECT_SAMPLE_FACTORS           	C761	C761_Hypothalamus	Brain Region:Hypothalamus | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 4; Number of pixels in region of interest=396; RAW_FILE_NAME=1A MALDI lipids B647 B648 C761 B427 20210512.raw
SUBJECT_SAMPLE_FACTORS           	C761	C761_Thalamus	Brain Region:Thalamus | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 4; Number of pixels in region of interest=491; RAW_FILE_NAME=1A MALDI lipids B647 B648 C761 B427 20210512.raw
SUBJECT_SAMPLE_FACTORS           	C761	C761_TOTAL	Brain Region:TOTAL | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 4; Number of pixels in region of interest=2400; RAW_FILE_NAME=1A MALDI lipids B647 B648 C761 B427 20210512.raw
SUBJECT_SAMPLE_FACTORS           	C762	C762_Hippocampus	Brain Region:Hippocampus | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=3 of 4; Number of pixels in region of interest=307; RAW_FILE_NAME=2A MALDI lipids B652 C762 C763 C202 20210513.raw
SUBJECT_SAMPLE_FACTORS           	C762	C762_Fiber Tracts	Brain Region:Fiber Tracts | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=3 of 4; Number of pixels in region of interest=242; RAW_FILE_NAME=2A MALDI lipids B652 C762 C763 C202 20210513.raw
SUBJECT_SAMPLE_FACTORS           	C762	C762_Iso Cortex	Brain Region:Iso Cortex | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=3 of 4; Number of pixels in region of interest=798; RAW_FILE_NAME=2A MALDI lipids B652 C762 C763 C202 20210513.raw
SUBJECT_SAMPLE_FACTORS           	C762	C762_Olfact. Area	Brain Region:Olfact. Area | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=3 of 4; Number of pixels in region of interest=117; RAW_FILE_NAME=2A MALDI lipids B652 C762 C763 C202 20210513.raw
SUBJECT_SAMPLE_FACTORS           	C762	C762_Cortical Subplate	Brain Region:Cortical Subplate | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=3 of 4; Number of pixels in region of interest=79; RAW_FILE_NAME=2A MALDI lipids B652 C762 C763 C202 20210513.raw
SUBJECT_SAMPLE_FACTORS           	C762	C762_Cerebral Nuclei	Brain Region:Cerebral Nuclei | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=3 of 4; Number of pixels in region of interest=113; RAW_FILE_NAME=2A MALDI lipids B652 C762 C763 C202 20210513.raw
SUBJECT_SAMPLE_FACTORS           	C762	C762_Hypothalamus	Brain Region:Hypothalamus | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=3 of 4; Number of pixels in region of interest=268; RAW_FILE_NAME=2A MALDI lipids B652 C762 C763 C202 20210513.raw
SUBJECT_SAMPLE_FACTORS           	C762	C762_Thalamus	Brain Region:Thalamus | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=3 of 4; Number of pixels in region of interest=628; RAW_FILE_NAME=2A MALDI lipids B652 C762 C763 C202 20210513.raw
SUBJECT_SAMPLE_FACTORS           	C762	C762_TOTAL	Brain Region:TOTAL | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=3 of 4; Number of pixels in region of interest=2552; RAW_FILE_NAME=2A MALDI lipids B652 C762 C763 C202 20210513.raw
SUBJECT_SAMPLE_FACTORS           	C763	C763_Hippocampus	Brain Region:Hippocampus | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 4; Number of pixels in region of interest=277; RAW_FILE_NAME=2A MALDI lipids B652 C762 C763 C202 20210513.raw
SUBJECT_SAMPLE_FACTORS           	C763	C763_Fiber Tracts	Brain Region:Fiber Tracts | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 4; Number of pixels in region of interest=301; RAW_FILE_NAME=2A MALDI lipids B652 C762 C763 C202 20210513.raw
SUBJECT_SAMPLE_FACTORS           	C763	C763_Iso Cortex	Brain Region:Iso Cortex | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 4; Number of pixels in region of interest=906; RAW_FILE_NAME=2A MALDI lipids B652 C762 C763 C202 20210513.raw
SUBJECT_SAMPLE_FACTORS           	C763	C763_Olfact. Area	Brain Region:Olfact. Area | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 4; Number of pixels in region of interest=133; RAW_FILE_NAME=2A MALDI lipids B652 C762 C763 C202 20210513.raw
SUBJECT_SAMPLE_FACTORS           	C763	C763_Cortical Subplate	Brain Region:Cortical Subplate | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 4; Number of pixels in region of interest=76; RAW_FILE_NAME=2A MALDI lipids B652 C762 C763 C202 20210513.raw
SUBJECT_SAMPLE_FACTORS           	C763	C763_Cerebral Nuclei	Brain Region:Cerebral Nuclei | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 4; Number of pixels in region of interest=187; RAW_FILE_NAME=2A MALDI lipids B652 C762 C763 C202 20210513.raw
SUBJECT_SAMPLE_FACTORS           	C763	C763_Hypothalamus	Brain Region:Hypothalamus | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 4; Number of pixels in region of interest=289; RAW_FILE_NAME=2A MALDI lipids B652 C762 C763 C202 20210513.raw
SUBJECT_SAMPLE_FACTORS           	C763	C763_Thalamus	Brain Region:Thalamus | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 4; Number of pixels in region of interest=539; RAW_FILE_NAME=2A MALDI lipids B652 C762 C763 C202 20210513.raw
SUBJECT_SAMPLE_FACTORS           	C763	C763_TOTAL	Brain Region:TOTAL | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 4; Number of pixels in region of interest=2708; RAW_FILE_NAME=2A MALDI lipids B652 C762 C763 C202 20210513.raw
SUBJECT_SAMPLE_FACTORS           	JJ3_73	JJ3_73_Hippocampus	Brain Region:Hippocampus | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 4; Number of pixels in region of interest=293; RAW_FILE_NAME=3B MALDI lipids B354 C384 JJ373 KK440 20210608.raw
SUBJECT_SAMPLE_FACTORS           	JJ3_73	JJ3_73_Fiber Tracts	Brain Region:Fiber Tracts | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 4; Number of pixels in region of interest=290; RAW_FILE_NAME=3B MALDI lipids B354 C384 JJ373 KK440 20210608.raw
SUBJECT_SAMPLE_FACTORS           	JJ3_73	JJ3_73_Iso Cortex	Brain Region:Iso Cortex | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 4; Number of pixels in region of interest=731; RAW_FILE_NAME=3B MALDI lipids B354 C384 JJ373 KK440 20210608.raw
SUBJECT_SAMPLE_FACTORS           	JJ3_73	JJ3_73_Olfact. Area	Brain Region:Olfact. Area | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 4; Number of pixels in region of interest=102; RAW_FILE_NAME=3B MALDI lipids B354 C384 JJ373 KK440 20210608.raw
SUBJECT_SAMPLE_FACTORS           	JJ3_73	JJ3_73_Cortical Subplate	Brain Region:Cortical Subplate | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 4; Number of pixels in region of interest=57; RAW_FILE_NAME=3B MALDI lipids B354 C384 JJ373 KK440 20210608.raw
SUBJECT_SAMPLE_FACTORS           	JJ3_73	JJ3_73_Cerebral Nuclei	Brain Region:Cerebral Nuclei | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 4; Number of pixels in region of interest=111; RAW_FILE_NAME=3B MALDI lipids B354 C384 JJ373 KK440 20210608.raw
SUBJECT_SAMPLE_FACTORS           	JJ3_73	JJ3_73_Hypothalamus	Brain Region:Hypothalamus | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 4; Number of pixels in region of interest=268; RAW_FILE_NAME=3B MALDI lipids B354 C384 JJ373 KK440 20210608.raw
SUBJECT_SAMPLE_FACTORS           	JJ3_73	JJ3_73_Thalamus	Brain Region:Thalamus | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 4; Number of pixels in region of interest=385; RAW_FILE_NAME=3B MALDI lipids B354 C384 JJ373 KK440 20210608.raw
SUBJECT_SAMPLE_FACTORS           	JJ3_73	JJ3_73_TOTAL	Brain Region:TOTAL | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 4; Number of pixels in region of interest=2237; RAW_FILE_NAME=3B MALDI lipids B354 C384 JJ373 KK440 20210608.raw
SUBJECT_SAMPLE_FACTORS           	JJ3_66	JJ3_66_Hippocampus	Brain Region:Hippocampus | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 4; Number of pixels in region of interest=165; RAW_FILE_NAME=4A MALDI lipids B425 C362 JJ366 KK496 20210611.raw
SUBJECT_SAMPLE_FACTORS           	JJ3_66	JJ3_66_Fiber Tracts	Brain Region:Fiber Tracts | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 4; Number of pixels in region of interest=317; RAW_FILE_NAME=4A MALDI lipids B425 C362 JJ366 KK496 20210611.raw
SUBJECT_SAMPLE_FACTORS           	JJ3_66	JJ3_66_Iso Cortex	Brain Region:Iso Cortex | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 4; Number of pixels in region of interest=711; RAW_FILE_NAME=4A MALDI lipids B425 C362 JJ366 KK496 20210611.raw
SUBJECT_SAMPLE_FACTORS           	JJ3_66	JJ3_66_Olfact. Area	Brain Region:Olfact. Area | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 4; Number of pixels in region of interest=139; RAW_FILE_NAME=4A MALDI lipids B425 C362 JJ366 KK496 20210611.raw
SUBJECT_SAMPLE_FACTORS           	JJ3_66	JJ3_66_Cortical Subplate	Brain Region:Cortical Subplate | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 4; Number of pixels in region of interest=72; RAW_FILE_NAME=4A MALDI lipids B425 C362 JJ366 KK496 20210611.raw
SUBJECT_SAMPLE_FACTORS           	JJ3_66	JJ3_66_Cerebral Nuclei	Brain Region:Cerebral Nuclei | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 4; Number of pixels in region of interest=158; RAW_FILE_NAME=4A MALDI lipids B425 C362 JJ366 KK496 20210611.raw
SUBJECT_SAMPLE_FACTORS           	JJ3_66	JJ3_66_Hypothalamus	Brain Region:Hypothalamus | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 4; Number of pixels in region of interest=238; RAW_FILE_NAME=4A MALDI lipids B425 C362 JJ366 KK496 20210611.raw
SUBJECT_SAMPLE_FACTORS           	JJ3_66	JJ3_66_Thalamus	Brain Region:Thalamus | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 4; Number of pixels in region of interest=514; RAW_FILE_NAME=4A MALDI lipids B425 C362 JJ366 KK496 20210611.raw
SUBJECT_SAMPLE_FACTORS           	JJ3_66	JJ3_66_TOTAL	Brain Region:TOTAL | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 4; Number of pixels in region of interest=2314; RAW_FILE_NAME=4A MALDI lipids B425 C362 JJ366 KK496 20210611.raw
SUBJECT_SAMPLE_FACTORS           	JJ3_76	JJ3_76_Hippocampus	Brain Region:Hippocampus | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 2; Number of pixels in region of interest=296; RAW_FILE_NAME=5B MALDI lipids JJ376 KK4116 20210611.raw
SUBJECT_SAMPLE_FACTORS           	JJ3_76	JJ3_76_Fiber Tracts	Brain Region:Fiber Tracts | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 2; Number of pixels in region of interest=234; RAW_FILE_NAME=5B MALDI lipids JJ376 KK4116 20210611.raw
SUBJECT_SAMPLE_FACTORS           	JJ3_76	JJ3_76_Iso Cortex	Brain Region:Iso Cortex | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 2; Number of pixels in region of interest=683; RAW_FILE_NAME=5B MALDI lipids JJ376 KK4116 20210611.raw
SUBJECT_SAMPLE_FACTORS           	JJ3_76	JJ3_76_Olfact. Area	Brain Region:Olfact. Area | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 2; Number of pixels in region of interest=186; RAW_FILE_NAME=5B MALDI lipids JJ376 KK4116 20210611.raw
SUBJECT_SAMPLE_FACTORS           	JJ3_76	JJ3_76_Cortical Subplate	Brain Region:Cortical Subplate | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 2; Number of pixels in region of interest=70; RAW_FILE_NAME=5B MALDI lipids JJ376 KK4116 20210611.raw
SUBJECT_SAMPLE_FACTORS           	JJ3_76	JJ3_76_Cerebral Nuclei	Brain Region:Cerebral Nuclei | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 2; Number of pixels in region of interest=45; RAW_FILE_NAME=5B MALDI lipids JJ376 KK4116 20210611.raw
SUBJECT_SAMPLE_FACTORS           	JJ3_76	JJ3_76_Hypothalamus	Brain Region:Hypothalamus | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 2; Number of pixels in region of interest=211; RAW_FILE_NAME=5B MALDI lipids JJ376 KK4116 20210611.raw
SUBJECT_SAMPLE_FACTORS           	JJ3_76	JJ3_76_Thalamus	Brain Region:Thalamus | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 2; Number of pixels in region of interest=542; RAW_FILE_NAME=5B MALDI lipids JJ376 KK4116 20210611.raw
SUBJECT_SAMPLE_FACTORS           	JJ3_76	JJ3_76_TOTAL	Brain Region:TOTAL | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=2 of 2; Number of pixels in region of interest=2267; RAW_FILE_NAME=5B MALDI lipids JJ376 KK4116 20210611.raw
SUBJECT_SAMPLE_FACTORS           	KK4_40	KK4_40_Hippocampus	Brain Region:Hippocampus | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 4; Number of pixels in region of interest=237; RAW_FILE_NAME=3B MALDI lipids B354 C384 JJ373 KK440 20210608.raw
SUBJECT_SAMPLE_FACTORS           	KK4_40	KK4_40_Fiber Tracts	Brain Region:Fiber Tracts | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 4; Number of pixels in region of interest=245; RAW_FILE_NAME=3B MALDI lipids B354 C384 JJ373 KK440 20210608.raw
SUBJECT_SAMPLE_FACTORS           	KK4_40	KK4_40_Iso Cortex	Brain Region:Iso Cortex | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 4; Number of pixels in region of interest=657; RAW_FILE_NAME=3B MALDI lipids B354 C384 JJ373 KK440 20210608.raw
SUBJECT_SAMPLE_FACTORS           	KK4_40	KK4_40_Olfact. Area	Brain Region:Olfact. Area | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 4; Number of pixels in region of interest=99; RAW_FILE_NAME=3B MALDI lipids B354 C384 JJ373 KK440 20210608.raw
SUBJECT_SAMPLE_FACTORS           	KK4_40	KK4_40_Cortical Subplate	Brain Region:Cortical Subplate | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 4; Number of pixels in region of interest=68; RAW_FILE_NAME=3B MALDI lipids B354 C384 JJ373 KK440 20210608.raw
SUBJECT_SAMPLE_FACTORS           	KK4_40	KK4_40_Cerebral Nuclei	Brain Region:Cerebral Nuclei | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 4; Number of pixels in region of interest=154; RAW_FILE_NAME=3B MALDI lipids B354 C384 JJ373 KK440 20210608.raw
SUBJECT_SAMPLE_FACTORS           	KK4_40	KK4_40_Hypothalamus	Brain Region:Hypothalamus | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 4; Number of pixels in region of interest=203; RAW_FILE_NAME=3B MALDI lipids B354 C384 JJ373 KK440 20210608.raw
SUBJECT_SAMPLE_FACTORS           	KK4_40	KK4_40_Thalamus	Brain Region:Thalamus | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 4; Number of pixels in region of interest=451; RAW_FILE_NAME=3B MALDI lipids B354 C384 JJ373 KK440 20210608.raw
SUBJECT_SAMPLE_FACTORS           	KK4_40	KK4_40_TOTAL	Brain Region:TOTAL | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 4; Number of pixels in region of interest=2114; RAW_FILE_NAME=3B MALDI lipids B354 C384 JJ373 KK440 20210608.raw
SUBJECT_SAMPLE_FACTORS           	KK4_96	KK4_96_Hippocampus	Brain Region:Hippocampus | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 4; Number of pixels in region of interest=235; RAW_FILE_NAME=4A MALDI lipids B425 C362 JJ366 KK496 20210611.raw
SUBJECT_SAMPLE_FACTORS           	KK4_96	KK4_96_Fiber Tracts	Brain Region:Fiber Tracts | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 4; Number of pixels in region of interest=254; RAW_FILE_NAME=4A MALDI lipids B425 C362 JJ366 KK496 20210611.raw
SUBJECT_SAMPLE_FACTORS           	KK4_96	KK4_96_Iso Cortex	Brain Region:Iso Cortex | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 4; Number of pixels in region of interest=749; RAW_FILE_NAME=4A MALDI lipids B425 C362 JJ366 KK496 20210611.raw
SUBJECT_SAMPLE_FACTORS           	KK4_96	KK4_96_Olfact. Area	Brain Region:Olfact. Area | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 4; Number of pixels in region of interest=138; RAW_FILE_NAME=4A MALDI lipids B425 C362 JJ366 KK496 20210611.raw
SUBJECT_SAMPLE_FACTORS           	KK4_96	KK4_96_Cortical Subplate	Brain Region:Cortical Subplate | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 4; Number of pixels in region of interest=79; RAW_FILE_NAME=4A MALDI lipids B425 C362 JJ366 KK496 20210611.raw
SUBJECT_SAMPLE_FACTORS           	KK4_96	KK4_96_Cerebral Nuclei	Brain Region:Cerebral Nuclei | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 4; Number of pixels in region of interest=161; RAW_FILE_NAME=4A MALDI lipids B425 C362 JJ366 KK496 20210611.raw
SUBJECT_SAMPLE_FACTORS           	KK4_96	KK4_96_Hypothalamus	Brain Region:Hypothalamus | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 4; Number of pixels in region of interest=208; RAW_FILE_NAME=4A MALDI lipids B425 C362 JJ366 KK496 20210611.raw
SUBJECT_SAMPLE_FACTORS           	KK4_96	KK4_96_Thalamus	Brain Region:Thalamus | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 4; Number of pixels in region of interest=466; RAW_FILE_NAME=4A MALDI lipids B425 C362 JJ366 KK496 20210611.raw
SUBJECT_SAMPLE_FACTORS           	KK4_96	KK4_96_TOTAL	Brain Region:TOTAL | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 4; Number of pixels in region of interest=2290; RAW_FILE_NAME=4A MALDI lipids B425 C362 JJ366 KK496 20210611.raw
SUBJECT_SAMPLE_FACTORS           	KK4_116	KK4_116_Hippocampus	Brain Region:Hippocampus | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 2; Number of pixels in region of interest=181; RAW_FILE_NAME=5B MALDI lipids JJ376 KK4116 20210611.raw
SUBJECT_SAMPLE_FACTORS           	KK4_116	KK4_116_Fiber Tracts	Brain Region:Fiber Tracts | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 2; Number of pixels in region of interest=257; RAW_FILE_NAME=5B MALDI lipids JJ376 KK4116 20210611.raw
SUBJECT_SAMPLE_FACTORS           	KK4_116	KK4_116_Iso Cortex	Brain Region:Iso Cortex | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 2; Number of pixels in region of interest=700; RAW_FILE_NAME=5B MALDI lipids JJ376 KK4116 20210611.raw
SUBJECT_SAMPLE_FACTORS           	KK4_116	KK4_116_Olfact. Area	Brain Region:Olfact. Area | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 2; Number of pixels in region of interest=224; RAW_FILE_NAME=5B MALDI lipids JJ376 KK4116 20210611.raw
SUBJECT_SAMPLE_FACTORS           	KK4_116	KK4_116_Cortical Subplate	Brain Region:Cortical Subplate | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 2; Number of pixels in region of interest=106; RAW_FILE_NAME=5B MALDI lipids JJ376 KK4116 20210611.raw
SUBJECT_SAMPLE_FACTORS           	KK4_116	KK4_116_Cerebral Nuclei	Brain Region:Cerebral Nuclei | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 2; Number of pixels in region of interest=131; RAW_FILE_NAME=5B MALDI lipids JJ376 KK4116 20210611.raw
SUBJECT_SAMPLE_FACTORS           	KK4_116	KK4_116_Hypothalamus	Brain Region:Hypothalamus | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 2; Number of pixels in region of interest=254; RAW_FILE_NAME=5B MALDI lipids JJ376 KK4116 20210611.raw
SUBJECT_SAMPLE_FACTORS           	KK4_116	KK4_116_Thalamus	Brain Region:Thalamus | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 2; Number of pixels in region of interest=396; RAW_FILE_NAME=5B MALDI lipids JJ376 KK4116 20210611.raw
SUBJECT_SAMPLE_FACTORS           	KK4_116	KK4_116_TOTAL	Brain Region:TOTAL | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 2; Number of pixels in region of interest=2249; RAW_FILE_NAME=5B MALDI lipids JJ376 KK4116 20210611.raw
SUBJECT_SAMPLE_FACTORS           	B427	B427_Hippocampus	Brain Region:Hippocampus | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 4; Number of pixels in region of interest=262; RAW_FILE_NAME=1A MALDI lipids B647 B648 C761 B427 20210512.raw
SUBJECT_SAMPLE_FACTORS           	B427	B427_Fiber Tracts	Brain Region:Fiber Tracts | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 4; Number of pixels in region of interest=321; RAW_FILE_NAME=1A MALDI lipids B647 B648 C761 B427 20210512.raw
SUBJECT_SAMPLE_FACTORS           	B427	B427_Iso Cortex	Brain Region:Iso Cortex | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 4; Number of pixels in region of interest=791; RAW_FILE_NAME=1A MALDI lipids B647 B648 C761 B427 20210512.raw
SUBJECT_SAMPLE_FACTORS           	B427	B427_Olfact. Area	Brain Region:Olfact. Area | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 4; Number of pixels in region of interest=142; RAW_FILE_NAME=1A MALDI lipids B647 B648 C761 B427 20210512.raw
SUBJECT_SAMPLE_FACTORS           	B427	B427_Cortical Subplate	Brain Region:Cortical Subplate | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 4; Number of pixels in region of interest=85; RAW_FILE_NAME=1A MALDI lipids B647 B648 C761 B427 20210512.raw
SUBJECT_SAMPLE_FACTORS           	B427	B427_Cerebral Nuclei	Brain Region:Cerebral Nuclei | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 4; Number of pixels in region of interest=186; RAW_FILE_NAME=1A MALDI lipids B647 B648 C761 B427 20210512.raw
SUBJECT_SAMPLE_FACTORS           	B427	B427_Hypothalamus	Brain Region:Hypothalamus | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 4; Number of pixels in region of interest=360; RAW_FILE_NAME=1A MALDI lipids B647 B648 C761 B427 20210512.raw
SUBJECT_SAMPLE_FACTORS           	B427	B427_Thalamus	Brain Region:Thalamus | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 4; Number of pixels in region of interest=445; RAW_FILE_NAME=1A MALDI lipids B647 B648 C761 B427 20210512.raw
SUBJECT_SAMPLE_FACTORS           	B427	B427_TOTAL	Brain Region:TOTAL | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 4; Number of pixels in region of interest=2592; RAW_FILE_NAME=1A MALDI lipids B647 B648 C761 B427 20210512.raw
SUBJECT_SAMPLE_FACTORS           	B354	B354_Hippocampus	Brain Region:Hippocampus | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=4 of 4; Number of pixels in region of interest=232; RAW_FILE_NAME=3B MALDI lipids B354 C384 JJ373 KK440 20210608.raw
SUBJECT_SAMPLE_FACTORS           	B354	B354_Fiber Tracts	Brain Region:Fiber Tracts | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=4 of 4; Number of pixels in region of interest=247; RAW_FILE_NAME=3B MALDI lipids B354 C384 JJ373 KK440 20210608.raw
SUBJECT_SAMPLE_FACTORS           	B354	B354_Iso Cortex	Brain Region:Iso Cortex | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=4 of 4; Number of pixels in region of interest=705; RAW_FILE_NAME=3B MALDI lipids B354 C384 JJ373 KK440 20210608.raw
SUBJECT_SAMPLE_FACTORS           	B354	B354_Olfact. Area	Brain Region:Olfact. Area | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=4 of 4; Number of pixels in region of interest=191; RAW_FILE_NAME=3B MALDI lipids B354 C384 JJ373 KK440 20210608.raw
SUBJECT_SAMPLE_FACTORS           	B354	B354_Cortical Subplate	Brain Region:Cortical Subplate | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=4 of 4; Number of pixels in region of interest=123; RAW_FILE_NAME=3B MALDI lipids B354 C384 JJ373 KK440 20210608.raw
SUBJECT_SAMPLE_FACTORS           	B354	B354_Cerebral Nuclei	Brain Region:Cerebral Nuclei | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=4 of 4; Number of pixels in region of interest=184; RAW_FILE_NAME=3B MALDI lipids B354 C384 JJ373 KK440 20210608.raw
SUBJECT_SAMPLE_FACTORS           	B354	B354_Hypothalamus	Brain Region:Hypothalamus | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=4 of 4; Number of pixels in region of interest=219; RAW_FILE_NAME=3B MALDI lipids B354 C384 JJ373 KK440 20210608.raw
SUBJECT_SAMPLE_FACTORS           	B354	B354_Thalamus	Brain Region:Thalamus | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=4 of 4; Number of pixels in region of interest=425; RAW_FILE_NAME=3B MALDI lipids B354 C384 JJ373 KK440 20210608.raw
SUBJECT_SAMPLE_FACTORS           	B354	B354_TOTAL	Brain Region:TOTAL | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=4 of 4; Number of pixels in region of interest=2326; RAW_FILE_NAME=3B MALDI lipids B354 C384 JJ373 KK440 20210608.raw
SUBJECT_SAMPLE_FACTORS           	B425	B425_Hippocampus	Brain Region:Hippocampus | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=4 of 4; Number of pixels in region of interest=184; RAW_FILE_NAME=4A MALDI lipids B425 C362 JJ366 KK496 20210611.raw
SUBJECT_SAMPLE_FACTORS           	B425	B425_Fiber Tracts	Brain Region:Fiber Tracts | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=4 of 4; Number of pixels in region of interest=272; RAW_FILE_NAME=4A MALDI lipids B425 C362 JJ366 KK496 20210611.raw
SUBJECT_SAMPLE_FACTORS           	B425	B425_Iso Cortex	Brain Region:Iso Cortex | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=4 of 4; Number of pixels in region of interest=805; RAW_FILE_NAME=4A MALDI lipids B425 C362 JJ366 KK496 20210611.raw
SUBJECT_SAMPLE_FACTORS           	B425	B425_Olfact. Area	Brain Region:Olfact. Area | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=4 of 4; Number of pixels in region of interest=166; RAW_FILE_NAME=4A MALDI lipids B425 C362 JJ366 KK496 20210611.raw
SUBJECT_SAMPLE_FACTORS           	B425	B425_Cortical Subplate	Brain Region:Cortical Subplate | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=4 of 4; Number of pixels in region of interest=121; RAW_FILE_NAME=4A MALDI lipids B425 C362 JJ366 KK496 20210611.raw
SUBJECT_SAMPLE_FACTORS           	B425	B425_Cerebral Nuclei	Brain Region:Cerebral Nuclei | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=4 of 4; Number of pixels in region of interest=203; RAW_FILE_NAME=4A MALDI lipids B425 C362 JJ366 KK496 20210611.raw
SUBJECT_SAMPLE_FACTORS           	B425	B425_Hypothalamus	Brain Region:Hypothalamus | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=4 of 4; Number of pixels in region of interest=189; RAW_FILE_NAME=4A MALDI lipids B425 C362 JJ366 KK496 20210611.raw
SUBJECT_SAMPLE_FACTORS           	B425	B425_Thalamus	Brain Region:Thalamus | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=4 of 4; Number of pixels in region of interest=384; RAW_FILE_NAME=4A MALDI lipids B425 C362 JJ366 KK496 20210611.raw
SUBJECT_SAMPLE_FACTORS           	B425	B425_TOTAL	Brain Region:TOTAL | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=4 of 4; Number of pixels in region of interest=2324; RAW_FILE_NAME=4A MALDI lipids B425 C362 JJ366 KK496 20210611.raw
SUBJECT_SAMPLE_FACTORS           	C202	C202_Hippocampus	Brain Region:Hippocampus | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 4; Number of pixels in region of interest=235; RAW_FILE_NAME=2A MALDI lipids B652 C762 C763 C202 20210513.raw
SUBJECT_SAMPLE_FACTORS           	C202	C202_Fiber Tracts	Brain Region:Fiber Tracts | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 4; Number of pixels in region of interest=316; RAW_FILE_NAME=2A MALDI lipids B652 C762 C763 C202 20210513.raw
SUBJECT_SAMPLE_FACTORS           	C202	C202_Iso Cortex	Brain Region:Iso Cortex | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 4; Number of pixels in region of interest=761; RAW_FILE_NAME=2A MALDI lipids B652 C762 C763 C202 20210513.raw
SUBJECT_SAMPLE_FACTORS           	C202	C202_Olfact. Area	Brain Region:Olfact. Area | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 4; Number of pixels in region of interest=153; RAW_FILE_NAME=2A MALDI lipids B652 C762 C763 C202 20210513.raw
SUBJECT_SAMPLE_FACTORS           	C202	C202_Cortical Subplate	Brain Region:Cortical Subplate | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 4; Number of pixels in region of interest=86; RAW_FILE_NAME=2A MALDI lipids B652 C762 C763 C202 20210513.raw
SUBJECT_SAMPLE_FACTORS           	C202	C202_Cerebral Nuclei	Brain Region:Cerebral Nuclei | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 4; Number of pixels in region of interest=137; RAW_FILE_NAME=2A MALDI lipids B652 C762 C763 C202 20210513.raw
SUBJECT_SAMPLE_FACTORS           	C202	C202_Hypothalamus	Brain Region:Hypothalamus | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 4; Number of pixels in region of interest=256; RAW_FILE_NAME=2A MALDI lipids B652 C762 C763 C202 20210513.raw
SUBJECT_SAMPLE_FACTORS           	C202	C202_Thalamus	Brain Region:Thalamus | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 4; Number of pixels in region of interest=492; RAW_FILE_NAME=2A MALDI lipids B652 C762 C763 C202 20210513.raw
SUBJECT_SAMPLE_FACTORS           	C202	C202_TOTAL	Brain Region:TOTAL | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=1 of 4; Number of pixels in region of interest=2436; RAW_FILE_NAME=2A MALDI lipids B652 C762 C763 C202 20210513.raw
SUBJECT_SAMPLE_FACTORS           	C384	C384_Hippocampus	Brain Region:Hippocampus | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=3 of 4; Number of pixels in region of interest=797; RAW_FILE_NAME=3B MALDI lipids B354 C384 JJ373 KK440 20210608.raw
SUBJECT_SAMPLE_FACTORS           	C384	C384_Fiber Tracts	Brain Region:Fiber Tracts | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=3 of 4; Number of pixels in region of interest=170; RAW_FILE_NAME=3B MALDI lipids B354 C384 JJ373 KK440 20210608.raw
SUBJECT_SAMPLE_FACTORS           	C384	C384_Iso Cortex	Brain Region:Iso Cortex | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=3 of 4; Number of pixels in region of interest=511; RAW_FILE_NAME=3B MALDI lipids B354 C384 JJ373 KK440 20210608.raw
SUBJECT_SAMPLE_FACTORS           	C384	C384_Olfact. Area	Brain Region:Olfact. Area | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=3 of 4; Number of pixels in region of interest=27; RAW_FILE_NAME=3B MALDI lipids B354 C384 JJ373 KK440 20210608.raw
SUBJECT_SAMPLE_FACTORS           	C384	C384_Cortical Subplate	Brain Region:Cortical Subplate | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=3 of 4; Number of pixels in region of interest=27; RAW_FILE_NAME=3B MALDI lipids B354 C384 JJ373 KK440 20210608.raw
SUBJECT_SAMPLE_FACTORS           	C384	C384_Cerebral Nuclei	Brain Region:Cerebral Nuclei | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=3 of 4; Number of pixels in region of interest=179; RAW_FILE_NAME=3B MALDI lipids B354 C384 JJ373 KK440 20210608.raw
SUBJECT_SAMPLE_FACTORS           	C384	C384_Hypothalamus	Brain Region:Hypothalamus | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=3 of 4; Number of pixels in region of interest=201; RAW_FILE_NAME=3B MALDI lipids B354 C384 JJ373 KK440 20210608.raw
SUBJECT_SAMPLE_FACTORS           	C384	C384_Thalamus	Brain Region:Thalamus | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=3 of 4; Number of pixels in region of interest=219; RAW_FILE_NAME=3B MALDI lipids B354 C384 JJ373 KK440 20210608.raw
SUBJECT_SAMPLE_FACTORS           	C384	C384_TOTAL	Brain Region:TOTAL | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=3 of 4; Number of pixels in region of interest=2131; RAW_FILE_NAME=3B MALDI lipids B354 C384 JJ373 KK440 20210608.raw
SUBJECT_SAMPLE_FACTORS           	C362	C362_Hippocampus	Brain Region:Hippocampus | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=3 of 4; Number of pixels in region of interest=247; RAW_FILE_NAME=4A MALDI lipids B425 C362 JJ366 KK496 20210611.raw
SUBJECT_SAMPLE_FACTORS           	C362	C362_Fiber Tracts	Brain Region:Fiber Tracts | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=3 of 4; Number of pixels in region of interest=272; RAW_FILE_NAME=4A MALDI lipids B425 C362 JJ366 KK496 20210611.raw
SUBJECT_SAMPLE_FACTORS           	C362	C362_Iso Cortex	Brain Region:Iso Cortex | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=3 of 4; Number of pixels in region of interest=839; RAW_FILE_NAME=4A MALDI lipids B425 C362 JJ366 KK496 20210611.raw
SUBJECT_SAMPLE_FACTORS           	C362	C362_Olfact. Area	Brain Region:Olfact. Area | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=3 of 4; Number of pixels in region of interest=218; RAW_FILE_NAME=4A MALDI lipids B425 C362 JJ366 KK496 20210611.raw
SUBJECT_SAMPLE_FACTORS           	C362	C362_Cortical Subplate	Brain Region:Cortical Subplate | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=3 of 4; Number of pixels in region of interest=136; RAW_FILE_NAME=4A MALDI lipids B425 C362 JJ366 KK496 20210611.raw
SUBJECT_SAMPLE_FACTORS           	C362	C362_Cerebral Nuclei	Brain Region:Cerebral Nuclei | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=3 of 4; Number of pixels in region of interest=222; RAW_FILE_NAME=4A MALDI lipids B425 C362 JJ366 KK496 20210611.raw
SUBJECT_SAMPLE_FACTORS           	C362	C362_Hypothalamus	Brain Region:Hypothalamus | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=3 of 4; Number of pixels in region of interest=303; RAW_FILE_NAME=4A MALDI lipids B425 C362 JJ366 KK496 20210611.raw
SUBJECT_SAMPLE_FACTORS           	C362	C362_Thalamus	Brain Region:Thalamus | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=3 of 4; Number of pixels in region of interest=461; RAW_FILE_NAME=4A MALDI lipids B425 C362 JJ366 KK496 20210611.raw
SUBJECT_SAMPLE_FACTORS           	C362	C362_TOTAL	Brain Region:TOTAL | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Position of tissue section on MALDI scan slide (from left to right)=3 of 4; Number of pixels in region of interest=2698; RAW_FILE_NAME=4A MALDI lipids B425 C362 JJ366 KK496 20210611.raw
#COLLECTION
CO:COLLECTION_SUMMARY            	Three different mice for each experimental group (18 mice in total) were
CO:COLLECTION_SUMMARY            	anesthetized via 5.0% isoflurane before exsanguination and transcardial
CO:COLLECTION_SUMMARY            	perfusion with ice-cold Dulbecco’s phosphate buffered saline (DPBS; Gibco #
CO:COLLECTION_SUMMARY            	14040133). Following perfusion, hemibrains were quickly removed, leaving behind
CO:COLLECTION_SUMMARY            	brainstem and cerebellum. Hemibrains were immediately placed in OCT compound
CO:COLLECTION_SUMMARY            	(Fisher HealthCare Tissue Plus O.C.T. Compound Clear 4585) and gently lowered
CO:COLLECTION_SUMMARY            	into isopentane (Sigma-Aldrich 2- Methylbutane M32631) in a beaker surrounded by
CO:COLLECTION_SUMMARY            	dry ice (isopentane chilled to approximately -70°C). Hemibrains were submerged
CO:COLLECTION_SUMMARY            	for 60 seconds, placed on dry ice, wrapped in aluminum foil, and stored at
CO:COLLECTION_SUMMARY            	-80°C until sectioning.
CO:SAMPLE_TYPE                   	Brain
#TREATMENT
TR:TREATMENT_SUMMARY             	All mice were group housed in sterile micro-isolator cages (Lab Products,
TR:TREATMENT_SUMMARY             	Maywood, NJ), and fed autoclaved food and acidified water ad libitum. No
TR:TREATMENT_SUMMARY             	additional treatment was applied, with the only comparisons being across
TR:TREATMENT_SUMMARY             	different genotypes and ages as specified in the study design table.
#SAMPLEPREP
SP:SAMPLEPREP_SUMMARY            	Prepared brain hemispheres were cryosectioned to 10 μm thick coronal sections
SP:SAMPLEPREP_SUMMARY            	at approximately Bregma -2.00 mm. Brain sections were mounted on glass slides
SP:SAMPLEPREP_SUMMARY            	and prepared for MALDI MSI as follows: After desiccation for one hour, slides
SP:SAMPLEPREP_SUMMARY            	were sprayed with 14 passes of 7mg/mL N-(1-Naphthyl) ethylenediamine
SP:SAMPLEPREP_SUMMARY            	dihydrochloride (NEDC) matrix (Sigma) in 70% methanol (HPLC-grade, Sigma) which
SP:SAMPLEPREP_SUMMARY            	was applied at 0.06mL/min with a 3mm offset and a velocity of 1200mm/min at
SP:SAMPLEPREP_SUMMARY            	30°C and 10psi using the M5 Sprayer with a heated tray of 50°C. Slides were
SP:SAMPLEPREP_SUMMARY            	used immediately or stored in a desiccator until analysis.
#CHROMATOGRAPHY
CH:CHROMATOGRAPHY_SUMMARY        	Not applicable (MALDI MSI)
CH:CHROMATOGRAPHY_TYPE           	None (Direct infusion)
CH:INSTRUMENT_NAME               	none
CH:COLUMN_NAME                   	none
CH:SOLVENT_A                     	N/A
CH:SOLVENT_B                     	N/A
CH:FLOW_GRADIENT                 	N/A
CH:FLOW_RATE                     	N/A
CH:COLUMN_TEMPERATURE            	N/A
#ANALYSIS
AN:ANALYSIS_TYPE                 	MS
#MS
MS:INSTRUMENT_NAME               	Waters Synapt G2 XS QTOF
MS:INSTRUMENT_TYPE               	QTOF
MS:MS_TYPE                       	MALDI
MS:ION_MODE                      	NEGATIVE
MS:MS_COMMENTS                   	For the detection of lipids, a Waters SynaptG2-Xs high-definition mass
MS:MS_COMMENTS                   	spectrometer equipped with traveling wave ion mobility was employed with the
MS:MS_COMMENTS                   	following parameters. The laser was operating at 2000 Hz with an energy of 300
MS:MS_COMMENTS                   	AU and spot size of 50 μm at X and Y coordinates of 100μm with mass range set
MS:MS_COMMENTS                   	at 50 – 1000 m/z in negative mode. MALDI-MSI data files were processed to
MS:MS_COMMENTS                   	adjust for mass drift during the MALDI scan and to enhance image quality and
MS:MS_COMMENTS                   	improve signal-tonoise ratio using an algorithm available within the
MS:MS_COMMENTS                   	High-Definition Imaging (HDI) software (Waters Corp). To adjust for mass drift
MS:MS_COMMENTS                   	during the MALDI scan, raw files were processed using a carefully curated list
MS:MS_COMMENTS                   	of 20 MALDI NEDC matrix peaks (m/z), 26 small molecule MALDI peaks(m/z), and 24
MS:MS_COMMENTS                   	lipid peaks(m/z). Files were processed at a sample duration of 10 sec at a
MS:MS_COMMENTS                   	frequency rate of 0.5 min, and an m/z window of 0.1 Da, using an internal lock
MS:MS_COMMENTS                   	mass of previously defined metabolite of taurine 124.007 m/z with a tolerance of
MS:MS_COMMENTS                   	1amu and a minimum signal intensity of 100,000 counts. Data acquisition
MS:MS_COMMENTS                   	spectrums were uploaded to the HDI software for the generation of lipid images.
MS:MS_COMMENTS                   	Regions of interest (ROIs) were user defined by a blinded investigator using
MS:MS_COMMENTS                   	anatomical reference points based on the mouse Allen Brain atlas. For all pixels
MS:MS_COMMENTS                   	defined within a ROI, peak intensities were averaged and normalized by total ion
MS:MS_COMMENTS                   	current (TIC) and number of pixels.
#MS_METABOLITE_DATA
MS_METABOLITE_DATA:UNITS	Intensity per pixel
MS_METABOLITE_DATA_START
Samples	B647_Hippocampus	B647_Fiber Tracts	B647_Iso Cortex	B647_Olfact. Area	B647_Cortical Subplate	B647_Cerebral Nuclei	B647_Hypothalamus	B647_Thalamus	B647_TOTAL	B648_Hippocampus	B648_Fiber Tracts	B648_Iso Cortex	B648_Olfact. Area	B648_Cortical Subplate	B648_Cerebral Nuclei	B648_Hypothalamus	B648_Thalamus	B648_TOTAL	B652_Hippocampus	B652_Fiber Tracts	B652_Iso Cortex	B652_Olfact. Area	B652_Cortical Subplate	B652_Cerebral Nuclei	B652_Hypothalamus	B652_Thalamus	B652_TOTAL	C761_Hippocampus	C761_Fiber Tracts	C761_Iso Cortex	C761_Olfact. Area	C761_Cortical Subplate	C761_Cerebral Nuclei	C761_Hypothalamus	C761_Thalamus	C761_TOTAL	C762_Hippocampus	C762_Fiber Tracts	C762_Iso Cortex	C762_Olfact. Area	C762_Cortical Subplate	C762_Cerebral Nuclei	C762_Hypothalamus	C762_Thalamus	C762_TOTAL	C763_Hippocampus	C763_Fiber Tracts	C763_Iso Cortex	C763_Olfact. Area	C763_Cortical Subplate	C763_Cerebral Nuclei	C763_Hypothalamus	C763_Thalamus	C763_TOTAL	B427_Hippocampus	B427_Fiber Tracts	B427_Iso Cortex	B427_Olfact. Area	B427_Cortical Subplate	B427_Cerebral Nuclei	B427_Hypothalamus	B427_Thalamus	B427_TOTAL	B354_Hippocampus	B354_Fiber Tracts	B354_Iso Cortex	B354_Olfact. Area	B354_Cortical Subplate	B354_Cerebral Nuclei	B354_Hypothalamus	B354_Thalamus	B354_TOTAL	B425_Hippocampus	B425_Fiber Tracts	B425_Iso Cortex	B425_Olfact. Area	B425_Cortical Subplate	B425_Cerebral Nuclei	B425_Hypothalamus	B425_Thalamus	B425_TOTAL	C202_Hippocampus	C202_Fiber Tracts	C202_Iso Cortex	C202_Olfact. Area	C202_Cortical Subplate	C202_Cerebral Nuclei	C202_Hypothalamus	C202_Thalamus	C202_TOTAL	C384_Hippocampus	C384_Fiber Tracts	C384_Iso Cortex	C384_Olfact. Area	C384_Cortical Subplate	C384_Cerebral Nuclei	C384_Hypothalamus	C384_Thalamus	C384_TOTAL	C362_Hippocampus	C362_Fiber Tracts	C362_Iso Cortex	C362_Olfact. Area	C362_Cortical Subplate	C362_Cerebral Nuclei	C362_Hypothalamus	C362_Thalamus	C362_TOTAL	JJ3_73_Hippocampus	JJ3_73_Fiber Tracts	JJ3_73_Iso Cortex	JJ3_73_Olfact. Area	JJ3_73_Cortical Subplate	JJ3_73_Cerebral Nuclei	JJ3_73_Hypothalamus	JJ3_73_Thalamus	JJ3_73_TOTAL	JJ3_66_Hippocampus	JJ3_66_Fiber Tracts	JJ3_66_Iso Cortex	JJ3_66_Olfact. Area	JJ3_66_Cortical Subplate	JJ3_66_Cerebral Nuclei	JJ3_66_Hypothalamus	JJ3_66_Thalamus	JJ3_66_TOTAL	JJ3_76_Hippocampus	JJ3_76_Fiber Tracts	JJ3_76_Iso Cortex	JJ3_76_Olfact. Area	JJ3_76_Cortical Subplate	JJ3_76_Cerebral Nuclei	JJ3_76_Hypothalamus	JJ3_76_Thalamus	JJ3_76_TOTAL	KK4_40_Hippocampus	KK4_40_Fiber Tracts	KK4_40_Iso Cortex	KK4_40_Olfact. Area	KK4_40_Cortical Subplate	KK4_40_Cerebral Nuclei	KK4_40_Hypothalamus	KK4_40_Thalamus	KK4_40_TOTAL	KK4_96_Hippocampus	KK4_96_Fiber Tracts	KK4_96_Iso Cortex	KK4_96_Olfact. Area	KK4_96_Cortical Subplate	KK4_96_Cerebral Nuclei	KK4_96_Hypothalamus	KK4_96_Thalamus	KK4_96_TOTAL	KK4_116_Hippocampus	KK4_116_Fiber Tracts	KK4_116_Iso Cortex	KK4_116_Olfact. Area	KK4_116_Cortical Subplate	KK4_116_Cerebral Nuclei	KK4_116_Hypothalamus	KK4_116_Thalamus	KK4_116_TOTAL
Factors	Brain Region:Hippocampus | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Fiber Tracts | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Iso Cortex | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Olfact. Area | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Cortical Subplate | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Cerebral Nuclei | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Hypothalamus | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Thalamus | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:TOTAL | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Hippocampus | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Fiber Tracts | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Iso Cortex | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Olfact. Area | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Cortical Subplate | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Cerebral Nuclei | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Hypothalamus | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Thalamus | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:TOTAL | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Hippocampus | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Fiber Tracts | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Iso Cortex | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Olfact. Area | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Cortical Subplate | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Cerebral Nuclei | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Hypothalamus | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Thalamus | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:TOTAL | Group:E3_young | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Hippocampus | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Fiber Tracts | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Iso Cortex | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Olfact. Area | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Cortical Subplate | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Cerebral Nuclei | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Hypothalamus | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Thalamus | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:TOTAL | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Hippocampus | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Fiber Tracts | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Iso Cortex | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Olfact. Area | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Cortical Subplate | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Cerebral Nuclei | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Hypothalamus | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Thalamus | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:TOTAL | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Hippocampus | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Fiber Tracts | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Iso Cortex | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Olfact. Area | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Cortical Subplate | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Cerebral Nuclei | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Hypothalamus | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Thalamus | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:TOTAL | Group:E4_young | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:3 months	Brain Region:Hippocampus | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Fiber Tracts | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Iso Cortex | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Olfact. Area | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Cortical Subplate | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Cerebral Nuclei | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Hypothalamus | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Thalamus | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:TOTAL | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Hippocampus | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Fiber Tracts | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Iso Cortex | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Olfact. Area | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Cortical Subplate | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Cerebral Nuclei | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Hypothalamus | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Thalamus | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:TOTAL | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Hippocampus | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Fiber Tracts | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Iso Cortex | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Olfact. Area | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Cortical Subplate | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Cerebral Nuclei | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Hypothalamus | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Thalamus | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:TOTAL | Group:E3_old | APOE genotype:E3/E3 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Hippocampus | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Fiber Tracts | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Iso Cortex | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Olfact. Area | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Cortical Subplate | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Cerebral Nuclei | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Hypothalamus | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Thalamus | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:TOTAL | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Hippocampus | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Fiber Tracts | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Iso Cortex | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Olfact. Area | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Cortical Subplate | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Cerebral Nuclei | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Hypothalamus | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Thalamus | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:TOTAL | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Hippocampus | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Fiber Tracts | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Iso Cortex | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Olfact. Area | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Cortical Subplate | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Cerebral Nuclei | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Hypothalamus | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Thalamus | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:TOTAL | Group:E4_old | APOE genotype:E4/E4 | 5XFAD Genotype:Wild-type | Age:24 months	Brain Region:Hippocampus | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Fiber Tracts | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Iso Cortex | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Olfact. Area | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Cortical Subplate | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Cerebral Nuclei | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Hypothalamus | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Thalamus | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:TOTAL | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Hippocampus | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Fiber Tracts | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Iso Cortex | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Olfact. Area | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Cortical Subplate | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Cerebral Nuclei | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Hypothalamus | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Thalamus | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:TOTAL | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Hippocampus | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Fiber Tracts | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Iso Cortex | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Olfact. Area | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Cortical Subplate | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Cerebral Nuclei | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Hypothalamus | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Thalamus | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:TOTAL | Group:E3_FAD | APOE genotype:E3/E3 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Hippocampus | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Fiber Tracts | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Iso Cortex | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Olfact. Area | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Cortical Subplate | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Cerebral Nuclei | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Hypothalamus | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Thalamus | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:TOTAL | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Hippocampus | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Fiber Tracts | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Iso Cortex | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Olfact. Area | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Cortical Subplate | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Cerebral Nuclei | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Hypothalamus | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Thalamus | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:TOTAL | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Hippocampus | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Fiber Tracts | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Iso Cortex | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Olfact. Area | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Cortical Subplate | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Cerebral Nuclei | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Hypothalamus | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:Thalamus | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months	Brain Region:TOTAL | Group:E4_FAD | APOE genotype:E4/E4 | 5XFAD Genotype:Hemizygous | Age:12 months
Cholesterol	12.0574	18.4341	13.1446	22.0063	12.1732	12.7711	16.7251	13.1086	120.4204	14.7058	17.3699	14.9129	15.7362	13.5913	14.8685	17.0324	15.4558	123.6728	20.0117	20.3042	19.1479	27.5819	18.9298	29.0197	26.8737	18.166	180.0349	20.5742	20.0912	17.5273	17.3885	15.9564	14.0206	21.6056	19.36	146.5238	21.0937	22.6633	19.0313	23.4868	20.0875	18.884	20.1733	16.6945	162.1144	15.4717	17.4733	17.3812	19.0927	16.6419	16.1472	18.3646	15.1142	135.6868	16.4723	23.7726	17.3037	16.6031	18.123	18.0776	16.744	17.4535	144.5498	12.588	20.218	12.8326	16.0771	12.5633	15.0461	15.3145	14.1301	118.7697	16.5366	25.318	15.4333	20.3614	18.314	19.7611	22.5292	19.1654	157.419	14.1174	19.6339	14.4782	14.2676	12.7069	13.7959	18.234	15.4571	122.691	17.1694	22.0346	16.2892	19.967	19.9825	17.1049	14.683	13.9022	141.1328	12.2106	21.829	12.2756	13.3895	13.1078	14.0846	16.8058	13.5101	117.213	27.1914	35.4042	24.308	24.5419	24.8085	26.0846	29.3316	31.9165	223.5867	27.2103	27.0136	20.5502	20.6766	19.7541	24.1086	41.2994	28.3432	208.956	23.053	51.8046	23.9396	31.4169	24.2155	27.8409	45.6238	38.2842	266.1785	17.8501	22.1299	14.8619	14.0685	14.3016	15.2145	18.6379	22.5687	139.6331	20.3534	33.4222	18.4687	20.8824	19.6769	22.28665	42.1398	33.192	210.42205	21.7628	32.1351	22.6325	28.1441	27.2311	29.3588	33.4969	32.4126	227.1739
Hydroxycholesterol	5.1427	5.5708	5.3402	8.1977	4.9811	5.2519	5.6302	4.4338	44.5484	5.612	6.147	5.876	6.8392	5.2105	5.3443	5.8408	5.1468	46.0166	7.8194	5.7261	7.5913	10.8258	6.6628	9.9126	8.204	5.4887	62.2307	7.6243	5.0107	7.1118	8.1225	6.5095	5.2926	6.3819	5.9294	51.9827	7.5525	7.2827	7.1521	8.0783	7.2344	7.8315	6.4614	4.7547	56.3476	5.509	4.7833	7.1969	8.088	5.8266	5.6076	6.5657	5.2601	48.8372	6.7855	6.1558	7.3157	7.7774	7.3056	7.3212	6.0503	5.5323	54.2438	5.0689	5.1701	5.1361	5.877	4.7902	5.8306	4.6423	4.5253	41.0405	5.5173	6.2404	5.4118	7.1982	6.1777	6.7093	6.0373	5.2652	48.5572	5.4203	5.5389	5.7091	5.6158	4.9129	5.0942	6.0864	5.0159	43.3935	6.1591	6.2125	5.8121	6.9489	6.6428	7.0165	4.3982	4.2073	47.3974	5.1033	4.3118	5.0008	5.1391	4.772	4.4542	5.0117	3.945	37.7379	9.6893	8.7848	9.5093	10.5488	8.2766	8.4466	9.0561	8.6497	72.9612	12.0818	7.4014	7.6022	8.8542	7.3751	11.0553	10.2948	6.2747	70.9395	8.9009	11.9079	9.1745	13.0202	8.5984	9.9419	11.7366	9.2316	82.512	6.0672	6.4988	5.6173	5.7563	4.5938	5.0577	5.6427	5.3283	44.5621	7.631	10.6683	7.6414	11.5342	7.5052	5.4503	8.508	6.7311	65.6695	6.7698	6.9175	7.6273	10.2068	7.055	5.8429	8.9255	6.5738	59.9186
LPC(1-acyl 16:0)	43.4939	47.7321	46.4437	42.7381	34.3054	41.2138	38.0459	37.4889	331.4618	44.4392	40.4031	46.9176	47.6969	40.3706	40.3509	41.9211	40.465	342.5644	49.0397	40.7601	47.0903	48.8349	41.2112	48.5219	41.601	39.4936	356.5527	54.6711	43.19	52.7148	53.996	47.7438	44.7919	43.9823	46.6484	387.7383	51.8957	48.436	48.12	45.6952	44.4379	49.633	43.5787	39.0756	370.8721	44.995	38.6868	48.2319	46.766	41.1879	43.4681	40.2023	40.1939	343.7319	47.7232	50.0076	52.5161	59.2842	54.3315	49.9229	46.1216	45.5671	405.4742	49.1131	48.3081	44.8088	46.4255	43.7507	47.4623	41.4804	46.2308	367.5797	45.2482	46.2129	40.1997	45.6136	41.2308	39.4785	40.8806	42.3706	341.2349	36.5231	36.4846	43.2142	37.9028	29.2612	28.6975	35.0095	28.5593	275.6522	50.7692	48.332	43.8626	33.6024	32.5592	39.9131	35.3765	40.2079	324.6229	56.0387	47.6775	51.4509	42.9213	41.9179	41.1964	40.1302	45.723	367.0559	61.1542	49.0695	55.1747	58.7214	54.4824	53.1235	53.7791	54.1858	439.6906	64.9254	52.1358	53.6965	56.3487	52.2115	66.1896	59.7532	39.6802	444.9409	49.1373	52.9513	47.9836	53.3691	50.2708	48.1036	46.4418	47.7699	396.0274	49.0244	48.3327	44.5312	43.0079	43.2316	44.1109	37.1646	41.5727	350.976	59.1665	71.4324	51.7634	65.3508	48.9697	43.3091	47.9433	49.1854	437.1206	42.8412	45.1078	45.5894	46.9011	42.9302	42.5073	42.968	40.7521	349.5971
LPC(1-acyl 18:2)	8.9379	10.7896	8.8063	12.6805	8.4918	9.007	9.9145	7.2498	75.8774	9.9286	11.2188	10.0102	11.6382	9.0004	9.0856	10.3906	8.544	79.8164	14.2974	11.5344	13.3029	17.9444	12.3562	16.2205	14.2166	9.7127	109.5851	14.1155	9.0028	12.5403	14.4732	11.0709	9.5336	12.5593	11.2763	94.5719	14.203	14.5084	12.7784	13.6826	13.9021	14.6084	12.1535	8.4874	104.3238	10.43	9.1237	13.0748	14.4511	10.7237	10.2036	11.573	9.6345	89.2144	12.4626	11.6952	12.9207	13.0286	13.659	12.8793	11.286	10.4397	98.3711	8.9647	9.3217	8.3232	9.3629	8.213	9.2946	8.0685	7.8018	69.3504	10.2755	11.9186	9.7864	12.9969	13.2347	12.755	11.8239	9.6165	92.4075	10.3994	10.9176	10.9693	10.5079	8.994	9.8664	11.561	8.7646	81.9802	10.3607	12.4853	9.4684	11.7204	11.4913	12.2357	7.5564	7.2587	82.5769	9.5906	8.4083	9.0921	9.3153	8.8204	8.4249	9.4571	8.016	71.1247	17.526	19.904	16.8323	18.3772	15.1999	15.7074	17.0401	16.7314	137.3183	18.9994	16.2558	14.6458	17.5262	16.5967	24.9268	23.7808	14.489	147.2205	18.6961	31.0974	18.3182	21.6902	18.8275	20.482	24.9461	22.028	176.0855	13.8255	15.1048	11.4956	11.3017	10.2691	10.6145	11.2863	11.8057	95.7032	17.3323	23.4471	16.4558	20.7561	16.772	11.50855	18.6719	16.0521	140.99585	13.8889	15.5112	15.8044	19.2603	14.7735	12.4026	19.1425	14.5203	125.3037
LPC(1-acyl 18:1)	14.8646	20.5007	15.9237	15.841	12.6638	14.4591	15.2288	14.0001	123.4818	16.9141	18.1973	16.9785	17.5991	15.3727	15.4134	16.2944	15.1207	131.8902	19.086	17.8199	18.1571	19.8917	15.5786	19.624	18.8746	15.7675	144.7994	21.0902	19.887	19.9946	21.0099	18.704	16.9209	19.4235	18.7061	155.7362	20.0628	21.4195	19.0501	18.1267	18.9343	19.7426	18.5318	16.0559	151.9237	16.3569	16.9934	19.0837	19.2886	16.2874	16.2588	17.0114	15.4079	136.6881	18.4883	22.6487	19.9933	21.7649	21.4784	19.3344	18.9339	17.5043	160.1462	16.7197	21.0656	15.3843	15.9512	15.0811	15.9374	16.485	16.3786	133.0029	16.8283	21.8191	15.4923	17.587	16.5976	15.7541	17.9356	16.8462	138.8602	13.9414	15.6558	15.8112	14.1077	11.6074	11.4665	14.4845	10.9632	108.0377	17.4011	20.2742	15.6641	13.5368	13.9623	15.0762	14.368	14.8586	125.1413	18.3926	22.748	17.1365	15.0804	15.5363	14.9455	15.6866	17.2501	136.776	23.205	23.9969	22.6581	24.2331	21.538	20.8281	22.8245	21.8616	181.1453	24.6673	23.4519	21.6277	22.0306	20.5172	26.9893	30.9041	19.8843	190.0724	22.4052	31.3013	21.6563	23.5043	22.1315	22.1365	26.7616	23.7399	193.6366	20.1131	24.8741	17.9181	17.1988	16.6222	18.2799	18.0602	19.2004	152.2668	19.7738	27.5037	20.7005	25.2777	20.0808	18.21815	22.4425	20.523	174.52015	16.5997	20.8243	19.3466	21.6394	17.6853	18.1564	21.4522	17.4768	153.1807
PC(diacyl 16:0/18:2)	19.6768	34.6777	20.4053	20.2977	16.777	19.8806	21.6593	20.944	174.3184	23.9863	28.7458	20.339	21.3311	19.5195	21.2526	22.8168	22.1235	180.1146	22.1798	26.9137	20.9912	22.9149	18.4034	22.1654	24.0087	22.0847	179.6618	24.0108	29.8845	22.6831	23.1335	21.8311	21.9334	24.888	25.0784	193.4428	22.5932	31.1327	21.3913	21.927	19.7323	23.9881	24.3216	22.546	187.6322	20.3007	26.2768	21.7526	22.3285	19.6163	20.6783	22.8348	21.9467	175.7347	22.5932	34.9143	24.019	25.464	25.675	25.349	25.7327	25.0807	208.8279	22.4748	35.949	19.884	20.6016	19.5264	21.6517	25.0306	24.3056	189.4237	22.524	33.0187	19.3338	21.6767	21.0494	22.1196	23.8769	23.5131	187.1122	18.2539	27.611	20.351	18.8488	15.227	16.7452	22.6718	19.0397	158.7484	22.7737	37.3417	19.9427	18.5327	18.5783	20.9659	22.1095	22.6116	182.8561	24.4345	32.4831	22.4304	20.3894	19.8064	21.3925	22.3382	23.8837	187.1582	26.4038	31.4901	25.317	28.1327	27.4994	24.8837	26.968	26.4146	217.1093	31.7447	35.2454	23.4635	24.833	23.715	44.3713	36.4149	23.8737	243.6615	21.9545	33.1511	21.3705	23.7198	24.2751	23.5265	26.8266	24.1976	199.0217	25.3243	33.3178	22.9471	23.3548	25.0662	24.3411	23.0694	25.5099	202.9306	24.0679	34.4301	23.1378	28.8303	22.2725	23.48155	26.1377	25.3618	207.71965	19.3576	28.6265	22.0171	26.177	23.2002	22.622	23.9957	21.7291	187.7252
Cer(18:1/20:4)-OH	117.8949	80.8697	115.17	107.1648	120.0267	113.2914	109.315	117.5605	881.293	113.1957	88.4531	118.6598	109.0012	115.3117	105.6037	113.8115	123.477	887.5137	117.6375	77.0531	119.1497	99.382	103.911	104.6876	107.4292	114.4838	843.7339	113.1224	78.9576	116.9765	109.0722	116.8625	110.736	103.7781	115.6186	865.1239	112.0146	82.0513	110.7949	97.1139	101.6778	102.6942	107.2738	112.9242	826.5447	112.8935	87.3546	112.7501	109.4272	114.2943	113.4724	109.8096	119.3289	879.3306	131.4604	84.7526	133.7751	115.2938	127.6019	121.1445	121.945	126.4248	962.3981	113.4427	71.5222	121.744	94.5317	97.1579	95.982	104.1871	109.8294	808.397	87.031	63.9832	99.5233	70.2453	85.5629	94.9401	90.4748	83.8202	675.5808	127.4648	88.4366	123.9873	108.1233	125.9226	122.2646	114.8862	139.7823	950.8677	102.6752	67.2248	109.8709	108.5298	99.5552	94.471	108.5916	106.9622	797.8807	107.0815	65.1141	107.2662	88.0202	99.1263	94.7419	103.573	103.0324	767.9556	104.4278	74.9559	109.7832	103.4644	101.9688	103.8069	100.3388	103.34	802.0858	103.2879	72.5487	101.5192	92.2478	94.4483	88.8766	73.2916	87.8968	714.1169	88.6229	51.6736	93.6971	71.3807	69.0679	52.8272	79.4096	87.8509	594.5299	118.261	91.1359	129.0174	117.98	116.0533	110.693	114.2493	116.0358	913.4257	91.1045	74.8868	87.8737	105.6838	89.2834	101.18815	96.3697	79.8759	726.26595	98.0917	76.4709	109.8862	104.0575	104.0813	91.6833	96.3053	93.6892	774.2654
SM(16:0)	13.1264	17.0729	12.7811	14.9546	11.2006	12.3869	12.6801	10.9471	105.1497	13.3614	15.3668	13.392	15.9293	12.0247	11.6818	12.0646	11.4436	105.2642	14.3533	12.0631	13.655	16.4066	11.4022	15.0364	13.7045	11.1441	107.7652	14.4877	10.8377	13.6545	13.8177	12.9719	11.6668	11.3145	12.396	101.1468	13.8497	15.8375	12.6372	13.1772	12.1066	15.4848	13.4292	10.1726	106.6948	12.7705	11.1541	14.534	14.7018	11.4148	11.4707	12.4018	12.468	100.9157	14.2816	13.7249	14.6475	14.8476	14.2026	14.5415	12.0594	11.5575	109.8626	11.9814	13.283	12.2532	13.0403	11.4763	12.5713	11.3668	11.0782	97.0505	9.5228	12.2974	8.5776	9.8031	9.6793	10.8482	9.2436	8.4114	78.3834	13.0971	11.786	13.708	12.3341	10.4382	10.7123	13.5818	10.7957	96.4532	13.379	17.0725	12.6361	13.7104	12.8605	15.6119	10.3772	10.2024	105.85	10.2797	8.7648	10.4246	10.3928	8.1689	8.4314	9.0694	8.449	73.9806	16.9895	16.7514	17.4151	19.4985	13.9661	14.0325	15.6758	13.8709	128.1998	14.7611	14.1743	11.0991	10.9991	10.2059	26.2271	16.679	7.912	112.0576	11.2561	13.3924	10.5687	12.841	10.0243	12.3033	11.5642	9.1227	91.0727	12.2969	14.231	11.7329	12.303	9.4347	10.3811	10.2377	9.337	89.9543	11.2533	18.0406	10.523	17.0036	9.8241	9.5916	10.4447	8.0494	94.7303	10.0056	12.096	11.4046	12.9601	9.2853	8.8021	11.2262	8.1828	83.9627
PC(16:1/14:0)	11.5893	14.0166	11.291	13.5131	10.3774	11.1936	11.6474	9.3199	92.9483	11.8603	13.2895	11.4286	14.4923	11.3404	10.4041	11.1764	9.7746	93.7662	13.0604	10.4417	11.9327	14.789	10.967	13.75	12.4061	9.6767	97.0236	12.9185	9.1484	12.1665	12.2756	11.2541	10.3664	10.127	10.7955	89.052	12.5285	13.7955	11.4801	12.3061	11.0254	14.2306	12.3895	8.966	96.7217	11.0812	9.1525	12.5022	12.9109	10.5218	10.3065	11.3728	10.8881	88.736	12.9398	11.1965	12.9153	13.0877	13.3554	13.2178	11.0402	10.1072	97.8599	11.2239	11.3367	11.0885	12.2721	11.0777	11.7855	10.7947	10.0719	89.651	9.4245	10.5571	7.9227	10.3821	9.9828	9.6145	8.9401	8.0904	74.9142	11.2012	9.7192	11.5859	10.5018	9.017	9.7036	11.9198	8.8573	82.5058	12.5638	13.8278	11.2574	13.2761	12.4499	14.0361	9.3771	9.0952	95.8834	9.8379	7.3561	9.5332	9.1621	8.1404	8.1478	8.648	7.6183	68.4438	14.851	13.583	15.3227	17.1016	12.2074	12.9477	14.1344	12.0569	112.2047	14.3004	11.5439	10.2978	10.4879	9.0991	22.9986	14.7138	7.2304	100.6719	10.617	11.4698	9.7634	12.1724	9.3157	11.1015	10.9238	8.6788	84.0424	11.2114	12.5975	10.5586	11.1314	8.6674	9.875	9.8431	8.4483	82.3327	10.7392	15.446	10.1676	15.1847	8.3467	8.775	9.6569	7.1423	85.4584	9.0598	9.7832	10.1772	11.4548	8.5923	7.675	10.3741	7.0571	74.1735
PC(16:0/14:1)	12.8971	16.4604	13.7792	14.8399	10.9505	12.5823	12.6857	10.6993	104.8944	12.6864	14.9385	14.2476	16.545	12.1785	12.6972	12.3503	11.2425	106.886	14.3244	12.5025	14.1302	16.959	12.4293	14.8388	13.4302	10.8665	109.4809	13.8968	12.3768	14.8416	15.179	13.5591	12.4966	11.7555	12.3572	106.4626	14.2728	16.3145	14.277	14.4255	14.1578	16.3441	14.0532	10.6362	114.4811	12.6162	11.3111	15.0077	14.5993	11.9652	11.9538	12.521	12.0028	101.9771	13.6411	13.2562	15.0001	15.917	14.4366	14.5259	12.4287	11.9827	111.1883	12.9393	13.5944	13.353	14.6442	12.8571	14.2568	12.0176	11.9744	105.6368	10.6292	12.1638	10.1798	11.7988	11.461	11.8042	10.5697	9.4866	88.0931	11.6335	11.0897	13.2235	12.3373	9.3311	10.4378	12.3181	8.985	89.356	14.1481	15.4031	13.3838	13.18	12.9175	15.2573	10.5124	10.6915	105.4937	11.964	9.7916	12.6573	11.5441	10.0026	10.2121	10.0493	9.299	85.52	17.1302	15.1441	18.0967	20.2207	14.5509	14.6879	15.8533	14.2538	129.9376	17.5401	13.6816	13.652	13.5086	11.5144	22.2905	16.8618	8.1842	117.2332	11.723	14.2919	12.4933	14.3907	11.4593	12.4354	12.5691	10.1155	99.4782	13.4488	14.1392	12.7288	14.0221	11.1329	12.1063	10.9938	9.8327	98.4046	12.7341	18.2154	12.9518	17.1393	11.3862	10.93605	11.4328	8.8843	103.67995	11.0607	11.0041	12.4993	14.5013	10.2649	9.7658	12.2711	8.6054	89.9726
PC[(18:1/14:1)/(16:0/16:2)/(16:1/16:1)]	15.734	20.3077	17.2781	19.213	14.9207	16.1331	16.2898	13.8558	133.7322	16.3438	21.4649	17.7778	21.9424	15.5935	15.7947	15.954	14.6002	139.4713	16.903	16.2143	17.2177	20.2194	15.233	18.624	17.53	13.826	135.7674	17.396	15.2753	17.982	18.1418	17.0366	15.8301	14.7775	15.1995	131.6388	16.6092	20.1111	16.6596	18.2027	16.3136	19.7679	17.8689	13.128	138.661	15.2046	14.5578	18.4115	18.5287	14.746	15.0857	16.2107	15.7142	128.4592	16.563	16.7105	18.1629	18.6916	17.4524	18.0848	15.159	14.4384	135.2626	15.2842	17.4248	16.3544	18.4443	16.2482	17.9519	15.1095	14.3947	131.212	12.6414	15.419	12.5834	14.6463	13.9204	15.2124	12.7133	11.6101	108.7463	15.1121	15.8069	16.711	15.3486	12.8021	14.4654	16.7926	12.8409	119.8796	17.3474	19.4435	16.7882	18.3254	16.6859	19.4465	14.4907	14.0699	136.5975	13.8251	12.8472	14.7204	14.4418	12.8372	13.2109	12.7912	11.5599	106.2337	20.8293	20.2012	22.7603	25.505	18.79	18.7852	19.5345	17.4746	163.8801	19.8435	16.5511	15.2451	15.897	13.7216	27.833	19.0698	10.5813	138.7424	15.3813	17.2179	14.9452	17.7266	13.4013	15.2644	15.2374	13.1077	122.2818	18.4023	20.1936	16.6643	18.7429	15.2058	16.2595	15.1418	13.3823	133.9925	14.8105	21.1803	14.5832	21.5167	13.361	14.02615	14.2133	10.7815	124.47265	13.408	14.2186	15.0392	18.2357	13.2637	11.7928	14.5721	10.5345	111.0646
PC(16:0/16:1)	30.9914	40.2856	37.5987	44.9851	31.3989	37.0184	33.6984	24.764	280.7405	31.4954	36.615	39.2035	50.8127	37.7482	36.0716	34.9107	26.3724	293.2295	32.0107	33.7975	33.3703	46.3359	35.5349	42.5639	35.1907	25.6784	284.4823	35.0544	34.057	38.4261	42.2602	40.2278	37.5945	32.7438	30.006	290.3698	32.9859	40.5789	35.1851	43.6614	38.7087	43.1959	36.4287	25.4625	296.2071	30.187	30.0176	35.7069	36.3459	32.011	32.2133	31.9664	26.4395	254.8876	29.6531	36.5401	36.1463	46.7585	41.6503	39.3275	33.6365	28.261	291.9733	33.5357	41.4886	33.0613	51.9034	45.6179	47.5004	35.8979	31.0688	320.074	31.1479	37.6636	29.1489	41.5069	34.4295	33.1251	31.9505	26.9711	265.9435	24.2457	28.69	30.4046	30.8178	24.1514	24.6884	29.1156	18.8227	210.9362	36.7117	40.3489	34.0933	35.1623	31.4568	39.7527	31.1953	28.3861	277.1071	34.3351	34.4268	36.204	40.5136	34.4589	35.1439	30.84	25.6419	271.5642	43.2225	39.557	45.1654	60.3278	45.5918	44.3495	43.5196	34.4099	356.1435	37.5078	35.0831	36.0384	43.4211	38.4957	49.4441	40.1144	22.4562	302.5608	30.4525	37.5353	32.0494	49.5175	38.8557	37.0518	33.5203	26.2815	285.264	35.3184	36.8353	31.8068	43.8739	37.5907	40.2676	31.0913	25.17	281.954	38.438	53.0109	34.7499	49.7053	37.6308	36.3994	38.0023	29.5568	317.4934	28.0265	34.6867	30.3214	41.6725	31.88	32.5312	32.8005	25.7961	257.7149
PC(16:0/16:0)	229.2549	206.7302	299.057	270.4069	197.717	223.9802	187.8184	170.7355	1785.7001	201.666	192.4886	299.4175	307.4906	229.9073	207.362	200.3669	178.3608	1817.0597	222.722	182.9673	261.3819	298.3026	225.4136	238.611	186.74	175.9302	1792.0686	245.0724	175.2161	299.9281	291.2716	248.3199	227.0138	183.5861	196.7539	1867.1619	245.0335	223.1411	290.1988	297.6333	260.2516	264.6585	218.065	179.1898	1978.1716	220.6146	169.8533	299.4604	257.997	204.7678	210.6965	172.2063	179.481	1715.0769	189.6861	163.0493	255.407	311.4503	247.6048	210.7863	180.0853	174.4117	1732.4808	260.3728	191.1725	287.0457	354.824	299.039	290.5228	203.8867	229.6922	2116.5557	228.3692	180.7457	255.7906	286.7047	213.5158	199.4972	186.272	184.6067	1735.5019	160.9457	117.5587	240.539	210.1953	140.4795	125.1926	134.3639	93.5275	1222.8022	285.2762	187.8654	288.6592	198.3589	173.8046	230.9399	171.5828	202.6242	1739.1112	296.9199	156.2105	336.9326	327.9718	261.864	225.6555	187.4023	197.9622	1990.9188	276.6226	169.0958	320.256	336.4081	259.52	238.1684	226.5753	203.3216	2029.9678	246.5711	166.7885	311.4625	303.3318	255.4375	252.6521	181.5157	122.3451	1840.1043	195.8531	147.1177	232.5848	279.5868	214.9756	199.1868	162.6254	143.4893	1575.4195	208.7387	163.5281	225.0254	236.4531	206.2242	214.7787	143.3558	127.7937	1525.8977	238.2822	236.1281	268.1726	303.6573	228.4678	178.02925	149.4289	141.5702	1743.73635	167.3906	106.0549	200.7541	200.3404	157.7719	141.2798	141.3217	102.439	1217.3524
PC[(18:3/16:0)] / PC[(16:0/16:0)]	1929.2285	1166.8086	1956.7671	2012.8536	1918.8842	1964.0952	1550.0293	1498.6282	13997.2947	1690.2037	1382.0352	1987.3796	2034.2166	1937.7163	1751.2898	1591.7487	1541.1321	13915.722	1964.9104	1380.8001	2057.1781	2110.3387	2037.4544	2016.8457	1500.4638	1496.4397	14564.4309	1844.2978	1113.1764	1917.6536	1933.0014	1892.2153	1818.1477	1427.5234	1453.5851	13399.6007	1975.4388	1443.5364	1995.9851	1922.9222	2018.7156	1918.1577	1594.2021	1429.9734	14298.9313	1878.7838	1329.179	1994.0674	2021.7501	1875.7697	1853.6256	1573.3581	1568.6173	14095.151	1933.077	1095.1074	1897.4352	1992.0885	1956.2305	1855.5809	1433.5755	1499.1581	13662.2531	1828.7514	1095.1936	1943.2666	1911.1382	1905.5651	1863.8803	1372.3023	1498.8676	13418.9651	1821.9049	1188.5049	1923.94	2053.0689	2083.0884	1913.5185	1458.2514	1490.5759	13932.8529	2009.8396	1204.3745	1975.0157	2056.5978	2029.3332	2046.9498	1458.5874	1488.8327	14269.5307	1875.1404	1160.3449	1952.1894	2225.6612	2096.2728	2013.8257	1430.3607	1495.4095	14249.2046	1969.1275	954.368	1996.7909	2049.8022	2037.1991	1905.8557	1585.3664	1445.5525	13944.0623	1887.627	1208.5905	1933.6532	1942.9072	1809.296	1790.0134	1522.0559	1468.7482	13562.8914	1885.2857	1240.2404	2001.6399	2115.7552	2045.4645	1566.7652	1102.932	1193.5491	13151.632	1966.0555	1076.6311	2078.8981	2001.2126	1938.441	1827.4196	1301.8197	1488.694	13679.1716	1995.6959	1382.4869	1968.5403	2046.0142	1908.9088	1853.6442	1590.8621	1436.6055	14182.7579	1860.8257	1374.818	1838.3604	1825.9318	1686.5943	1649.02835	1342.305	1363.0688	12940.93235	2019.2516	1035.8095	1951.6505	1860.3085	1778.1797	1444.4125	1530.9162	1349.3582	12969.8867
PC(18:2/16:0)	291.9505	180.6916	300.7662	304.3671	283.5752	292.1431	224.9584	222.3549	2100.807	251.3682	210.0475	306.3248	314.4367	293.2409	260.2904	230.2114	228.2921	2094.212	281.093	194.6011	295.5561	295.2774	285.2744	281.4759	209.7511	216.6724	2059.7014	268.5187	163.613	290.6104	289.1751	282.6414	270.1225	198.9596	212.3707	1976.0114	278.0663	208.5497	289.159	282.391	285.0659	275.0005	226.6266	204.816	2049.675	278.9955	193.714	295.3708	294.0554	277.8354	270.6639	220.1038	232.2722	2063.011	289.8189	166.2381	294.0388	313.0665	302.7432	283.415	213.8451	223.2222	2086.3878	281.9239	169.3401	307.1493	307.8473	301.7602	293.7967	209.7301	230.6829	2102.2305	269.3509	174.3408	290.7845	298.915	295.538	273.8039	196.6856	209.4901	2008.9088	299.0324	171.5655	301.0198	304.9106	290.9842	290.1629	210.69	216.3301	2084.6955	297.9537	184.3718	306.0428	332.6957	314.8103	311.3442	219.6571	234.4243	2201.2999	297.027	135.9124	305.3888	307.2964	299.1569	275.4668	224.225	212.7816	2057.2549	284.8939	172.5448	298.2601	301.1118	266.7435	262.7992	219.8914	210.4272	2016.6719	267.3753	166.1407	283.2684	287.1474	271.3002	228.6179	149.5913	145.4766	1798.9178	252.971	130.5364	264.5787	263.2982	240.8454	232.109	158.1625	173.5653	1716.0665	306.5339	209.4644	308.0668	319.3452	293.4849	285.2087	233.513	208.2845	2163.9014	271.4127	204.4453	272.9255	259.0836	232.5022	236.9455	176.6246	178.0158	1831.9552	252.67	132.3784	258.7819	258.1101	232.2406	188.6823	181.4924	156.2039	1660.5596
PC(18:1/16:0)	331.8152	463.2683	414.2547	376.5174	313.4899	339.1337	368.5675	341.1777	2948.2244	332.0951	357.0508	411.1387	412.3875	345.0567	344.1329	378.1625	338.6839	2918.7081	319.4493	372.5817	355.3874	371.4685	331.6121	347.5493	375.0266	352.0222	2825.0971	364.2118	437.3452	416.8808	399.3678	372.6328	362.4785	390.9239	395.6324	3139.4732	341.812	427.1788	392.7304	424.8082	364.7198	403.5683	400.934	378.1616	3133.9131	330.844	366.9345	395.2471	341.1999	319.9413	339.5797	336.6072	334.8013	2765.155	282.5504	414.6303	363.2617	402.4182	343.9564	310.9014	373.0273	346.4101	2837.1558	382.3356	456.9843	396.9326	461.4642	412.0857	418.6808	430.2436	430.1887	3388.9155	348.7717	444.3724	365.977	372.5926	291.9521	315.1143	402.1858	376.1194	2917.0853	236.8838	282.3679	335.2106	292.8934	218.5337	198.16	276.4559	200.3851	2040.8904	395.8433	403.1859	396.7425	254.335	246.962	312.4085	361.5344	384.5973	2755.6089	397.355	490.0708	437.1288	414.5791	360.8114	355.4668	369.318	409.3153	3234.0452	399.159	407.7681	435.8327	445.3207	399.6145	387.1244	451.75	414.9081	3341.4775	353.1701	385.3619	410.6342	373.9303	346.3383	381.7027	490.6459	355.1933	3096.9767	297.4928	394.3512	324.9734	383.7257	333.1953	306.6312	391.7011	325.1799	2757.2506	309.1271	356.3808	330.5886	332.3098	320.9515	349.9136	309.33	301.3482	2609.9496	359.043	464.1375	396.4755	450.4073	389.6467	345.1289	374.0179	350.2594	3129.1162	269.8472	360.1852	308.2548	300.6411	276.6322	340.3442	318.1902	293.6649	2467.7598
PC(18:0/16:0)	127.0092	138.371	157.4693	139.8843	118.6812	121.1544	127.9896	124.182	1054.741	116.8293	123.882	154.6932	154.1625	127.1262	117.763	131.0912	123.6659	1049.2133	117.4884	108.4962	133.9256	136.1578	111.1284	120.1158	132.2368	125.1711	984.7201	125.8188	121.857	153.9491	141.8267	128.6162	124.6207	125.0738	134.4617	1056.224	125.2958	132.233	146.2883	149.7731	129.3599	139.318	142.081	132.6354	1096.9845	121.0537	113.1628	153.7166	132.5989	115.5822	120.079	117.0619	124.7932	998.0483	108.6364	114.5595	141.0688	141.7451	124.4759	114.0118	127.075	120.502	992.0745	143.6572	126.6212	162.3844	173.5071	154.1066	148.1949	149.5652	151.0368	1209.0734	114.7385	113.5169	134.5908	125.9917	103.4754	103.4629	126.3297	118.791	940.8969	98.6563	87.3479	132.1198	106.6288	85.5814	78.7125	97.9753	81.7225	768.7445	148.8914	120.7861	160.8765	114.5509	109.2846	127.1758	130.3374	140.3225	1052.2252	145.1867	111.0615	166.9661	151.4707	128.1353	116.0531	125.4361	133.647	1077.9565	140.4946	113.1144	167.341	163.6842	138.9598	129.88	144.4786	135.482	1133.4346	116.3189	101.255	147.0348	127.0726	116.3753	131.5957	127.0111	102.7139	969.3773	102.8306	94.562	114.9442	126.9166	104.3336	102.3126	123.0149	100.0028	868.9173	116.7632	110.7103	128.3167	125.4185	116.3119	119.9479	103.7846	98.9434	920.1965	109.4147	125.6481	133.5014	148.2902	121.3352	104.57135	103.2656	95.0702	941.09675	82.8319	84.6131	101.5872	104.3875	85.6994	89.1948	96.7118	77.5709	722.5966
SM(18:0)	189.74	102.439	151.947	144.2534	151.7905	144.1183	142.8372	187.9596	1215.085	169.8016	114.1477	166.7772	132.6978	142.7776	147.8173	145.1724	188.2254	1207.417	174.9532	97.6601	162.393	120.2494	130.9186	134.7875	142.5257	174.4569	1137.9444	167.9403	102.7145	152.9104	121.1295	138.6573	147.1294	135.4074	179.818	1145.7068	162.954	96.5902	140.1231	131.0503	124.9946	119.8723	131.6478	170.027	1077.2593	176.1444	118.721	149.8901	124.3447	142.6096	155.8114	130.7008	177.9188	1176.1408	210.6292	116.7066	192.4101	147.9367	160.6363	155.3733	172.269	202.4789	1358.4401	196.0263	106.4935	205.0618	149.671	162.7079	155.6955	154.5091	188.2716	1318.4367	186.0873	101.512	204.6633	134.2665	142.5219	125.0857	145.0955	198.5447	1237.7769	227.1655	143.3756	197.7303	155.8901	174.5707	175.9568	168.7615	257.0914	1500.5419	189.0169	112.1715	189.4684	162.928	161.5293	144.2592	163.1437	188.1889	1310.7059	183.2552	95.9993	174.4681	127.5292	135.8562	134.1351	152.8925	204.9482	1209.0838	167.5548	108.0721	153.111	131.4024	144.2116	149.9112	136.3905	171.0949	1161.7485	180.1905	111.57	171.1967	123.4627	129.5864	115.0947	125.7181	177.5317	1134.3508	169.6958	90.2338	176.3694	147.246	132.2515	161.8873	149.3252	201.7827	1228.7917	154.652	131.4376	194.3172	136.7612	145.6363	153.745	143.8747	207.972	1268.396	200.6878	134.6132	191.6601	152.0164	168.3375	169.6559	188.4634	220.7371	1426.1714	190.5988	133.5494	208.0416	138.8488	197.9369	185.5668	144.6685	208.9589	1408.1697
PC(16:0/18:2)	104.5439	118.9612	112.8145	105.8777	108.1475	104.3348	95.6224	109.8354	860.1374	111.1785	116.7194	121.7975	111.5648	113.2404	110.6417	100.3425	120.9556	906.4404	107.8402	119.3264	117.2978	108.847	109.0796	107.0033	96.019	111.7576	877.1709	98.478	112.1325	106.1786	97.9657	101.3843	98.6973	93.3522	105.1385	813.3271	97.6036	109.2131	105.38	93.7552	97.8531	102.9766	91.2728	102.297	800.3514	98.5713	107.9559	99.9825	95.5606	98.2205	94.6138	89.6759	108.5135	793.094	106.0715	120.089	117.588	107.2256	107.1699	116.2729	102.0297	108.2155	884.6621	104.7487	114.916	114.8741	107.7481	110.146	108.7839	100.2117	108.5058	869.9343	101.9704	125.1298	114.8334	96.465	99.5485	111.0545	91.0779	105.8778	845.9573	111.2712	120.0883	121.4104	118.1436	107.2499	112.9857	116.0826	119.6488	926.8805	110.2976	160.7202	121.324	110.1902	114.7004	132.8489	107.4302	117.6922	975.2037	92.5561	109.8006	102.6267	96.5246	94.9994	96.9252	88.7829	107.4694	789.6849	125.342	121.8877	132.3559	131.7427	118.8435	115.2101	100.1723	115.3348	960.889	102.2206	106.2708	102.2084	98.0782	91.5721	139.2967	99.0384	96.2246	834.9098	97.8896	100.3913	102.8172	103.6369	103.668	115.6382	85.956	92.9372	802.9344	118.1515	118.4538	119.9326	141.5186	118.9974	123.3932	109.4717	106.7549	956.6737	150.7926	159.199	170.9381	124.9819	138.0449	126.9545	137.4104	163.3596	1171.681	118.9806	124.6298	121.2151	134.8256	115.0805	130.5158	95.0663	120.8673	961.181
PC[(18:3/18:1)/(18:2/18:2)]/PC[(16:0/18:1)]	2541.3781	2311.0897	2532.9858	2510.6146	2621.125	2645.1203	2733.038	2717.5532	20612.9047	2479.7698	2399.2577	2534.0886	2503.4893	2568.0361	2605.4824	2675.1777	2662.9561	20428.2577	2507.4801	2457.5613	2554.9209	2430.6101	2592.7502	2564.5069	2620.9001	2653.2885	20382.0181	2468.2848	2438.4956	2477.4432	2423.4369	2553.7103	2603.2622	2661.522	2613.1414	20239.2964	2467.7312	2392.5489	2483.1739	2459.9635	2517.4943	2579.5693	2632.3771	2656.92	20189.7782	2505.4769	2497.3305	2490.0277	2418.6543	2560.1064	2626.9174	2690.6397	2648.456	20437.6089	2540.6594	2437.2784	2500.3604	2370.0283	2413.8343	2440.4015	2671.6445	2656.6059	20030.8127	2482.1242	2332.1316	2522.2494	2344.0353	2426.7875	2466.097	2598.0621	2597.5417	19769.0288	2439.9605	2430.7746	2507.1334	2381.7665	2458.3693	2472.0348	2657.39	2668.0271	20015.4562	2610.4428	2584.1345	2576.9865	2558.489	2690.0109	2754.1564	2785.5295	2811.1224	21370.872	2398.9919	2241.882	2495.4793	2478.957	2527.2933	2437.9715	2670.1318	2601.4311	19852.1379	2418.1056	2533.3926	2450.5881	2393.4731	2500.7248	2602.703	2691.0479	2686.6492	20276.6843	2443.8704	2486.627	2441.205	2409.6377	2505.5404	2580.6029	2622.3564	2622.8247	20112.6645	2411.0712	2471.9744	2457.8341	2381.9562	2437.1437	2195.9534	2574.1046	2769.312	19699.3496	2593.0667	2615.4726	2635.2313	2464.8326	2592.4744	2456.183	2715.4005	2908.9341	20981.5952	2643.1085	2575.07	2651.3089	2593.8569	2634.2991	2683.7255	2843.9036	2832.9097	21458.1822	2484.8805	2473.9674	2442.8461	2486.4769	2520.2008	2768.4555	2755.222	2748.0824	20680.1316	2786.9186	2900.0741	2721.3936	2491.2177	2663.8524	2853.1855	2886.1186	3092.6137	22395.3742
PC[(18:2/18:1)/(16:0/20:3)]/PC[(16:0/18:0)]	801.6071	623.4157	855.971	803.7736	863.3946	811.475	859.3708	868.3768	6487.3846	763.0745	675.054	872.5427	811.8188	846.5961	778.0073	872.9115	871.9755	6491.9804	819.4056	658.8125	888.7238	800.3088	825.1629	802.673	877.2429	878.9392	6551.2687	783.4834	633.4243	855.964	820.1275	813.8647	803.1511	836.1402	848.0877	6394.2429	809.8618	688.384	880.9693	819.9455	831.936	829.459	877.326	893.1693	6631.0509	800.5572	712.6661	885.9222	845.3055	833.2167	836.4113	857.2992	874.7642	6646.1424	794.1199	607.0253	848.5935	754.6536	775.5992	738.2461	866.6606	854.7389	6239.6371	800.954	575.0974	879.3668	749.2817	760.9509	737.9411	826.6807	833.5449	6163.8175	780.5377	615.7174	898.344	787.166	814.5224	766.2559	859.8351	854.4248	6376.8033	805.3226	622.1185	874.9182	804.9322	846.7357	826.6437	816.4868	875.9478	6473.1055	777.7279	581.0047	871.6321	818.973	826.8086	769.0869	847.9564	844.1153	6337.3049	801.7156	577.024	871.0568	800.5413	841.3481	792.7414	877.3317	847.4201	6409.179	777.9733	645.1773	854.2694	782.0314	805.3138	801.7152	826.2527	834.7681	6327.5012	765.918	628.738	874.7723	802.0712	810.6111	648.8749	662.6926	857.3264	6051.0045	833.2597	524.4212	908.4429	782.4887	803.2805	740.4552	821.189	844.6777	6258.2149	847.2479	729.156	922.369	850.7502	870.2869	839.2696	872.595	896.7994	6828.474	745.5268	630.3701	852.5334	832.4456	796.6576	780.3057	779.8893	768.9272	6186.6557	756.0888	619.1745	826.0224	757.1372	753.5335	721.3418	790.66	769.168	5993.1262
PC[(18:0/18:2)/(18:1/18:1)]	103.0955	106.4581	116.5591	105.1544	109.4274	100.8485	112.2076	115.231	868.9816	101.5427	99.9389	117.7703	110.2093	108.7871	100.2407	114.4193	115.8652	868.7735	98.6751	89.4277	106.8341	96.7963	93.1431	93.6005	115.6856	114.9086	809.071	101.5524	103.155	115.0678	108.5253	107.0197	104.7319	110.7816	116.6748	867.5085	97.7592	101.1233	109.5783	107.2714	100.3428	106.2353	116.0631	120.8564	859.2298	101.2996	101.5271	113.8574	104.2139	103.6319	103.3856	107.311	115.2639	850.4904	98.7442	100.2265	116.4629	103.3118	101.901	96.8814	120.7077	113.71	851.9455	111.2901	100.8155	124.9974	112.3392	108.3101	105.2055	126.4229	122.1881	911.5688	99.607	101.2067	116.0582	97.078	95.0624	92.1167	109.6992	109.7462	820.5744	94.5286	79.7542	112.6053	94.5729	92.355	86.4742	99.1772	104.4082	763.8756	107.9568	101.4355	120.3311	97.8854	98.7812	100.5021	120.8194	122.2412	869.9527	107.2051	102.3905	118.6099	104.2672	104.838	97.0557	112.8542	116.2037	863.4243	100.4692	88.632	114.1638	105.2712	100.1772	99.549	109.9921	106.8103	825.0648	93.8039	84.2292	105.9965	94.6835	90.0063	97.3164	93.7752	104.35	764.161	94.8461	76.521	98.1262	91.1006	86.6921	85.6944	107.2769	96.6697	736.927	103.0254	96.8363	119.5238	109.0012	108.8588	106.6067	108.4569	107.6075	859.9166	87.262	89.0799	107.9086	98.8994	91.2956	95.02145	96.516	92.7842	758.76715	74.4782	75.8684	89.0596	89.0935	80.8733	83.4362	86.954	79.0132	658.7764
PC(18:0/18:1)	117.3034	333.88	133.7139	117.6749	107.019	115.5978	163.5437	166.4077	1255.1404	158.4389	230.0882	124.8163	126.0583	114.7359	145.0001	158.9974	155.3737	1213.5088	105.8252	233.3278	104.3008	111.1577	97.3523	104.135	172.9997	170.7824	1099.8809	126.5988	313.4261	128.6121	130.6238	122.8615	139.5851	176.6383	186.3632	1324.7089	109.986	256.7841	119.408	132.7872	105.9766	125.7948	168.0403	191.9234	1210.7004	122.4662	240.3096	123.1684	123.6163	115.4737	122.2561	150.3885	155.0726	1152.7514	98.7449	284.1634	120.6665	120.6816	110.2397	121.4058	163.1738	156.2795	1175.3552	135.9405	332.0487	131.9198	148.7839	137.6786	148.7379	225.5346	194.935	1455.579	130.4395	292.5414	114.3702	105.8571	90.9292	131.5349	175.5958	159.9158	1201.1839	88.7335	189.7207	110.7665	98.0729	74.5024	70.9409	124.4532	102.3962	859.5863	133.7941	293.1098	130.4682	89.057	89.8848	114.9898	181.1585	187.157	1219.6192	128.0206	341.5823	132.8685	130.2463	108.4572	131.5965	154.4867	175.716	1302.9741	118.5178	231.5491	125.9985	128.93	116.8561	120.0562	167.5463	162.6279	1172.0819	111.2151	229.4032	108.1777	98.7065	93.1539	181.4627	233.4283	174.9539	1230.5013	89.8147	239.2193	84.931	96.5273	95.4369	108.8487	164.7099	114.9881	994.4759	106.2197	186.895	100.2754	100.6277	99.6542	110.0106	125.7055	126.2881	955.6762	92.0302	185.5418	104.5497	120.171	106.2175	117.93075	142.2091	134.1619	1002.81195	75.1834	186.7081	85.7901	99.0336	85.4347	125.8509	117.8963	110.0247	885.9218
PC (diacyl 16:0/18:2)	67.4809	80.5313	65.3478	69.1424	62.2713	64.183	66.254	71.8618	547.0725	70.6545	83.2438	65.9536	66.6909	63.3758	69.5953	66.3203	72.4356	558.2698	70.2372	72.9961	67.8296	71.3847	64.2032	70.2886	68.6914	71.1168	556.7476	72.6318	79.6645	70.2731	69.8138	65.7507	66.4521	69.6164	75.6465	569.8489	70.5733	76.1391	67.9146	66.4789	65.615	67.9698	65.6726	68.6197	548.983	68.5944	73.5573	68.8488	69.4123	66.1024	65.9419	66.9267	74.6149	553.9987	72.6826	83.184	73.4195	73.4592	71.2448	75.6922	71.4038	76.0307	597.1168	67.4703	81.4774	68.4314	68.5188	67.3806	70.1104	68.7113	73.0941	565.1943	72.5822	80.5164	71.6068	72.608	71.5275	73.2975	68.0942	79.9573	590.1899	67.4667	83.6705	69.9127	64.7526	59.6235	63.6514	74.5347	79.3413	562.9534	73.55	86.5938	69.6606	70.0527	69.354	73.9749	70.3414	76.8209	590.3483	66.4852	73.8298	64.9641	63.0004	60.2069	61.2734	63.2631	72.0583	525.0812	75.2536	89.1573	74.2864	76.5499	71.6965	72.397	73.7866	79.3405	612.4678	75.0243	81.1276	70.1084	68.9299	68.7915	88.5593	98.4072	75.6128	626.561	71.1027	84.129	68.2359	75.0796	69.6507	80.6159	74.7764	76.0886	599.6788	64.8652	88.1665	66.211	62.9036	61.6072	65.3993	67.2668	78.7471	555.1667	83.9372	91.0856	81.5289	82.5396	77.6216	71.79815	80.8773	86.9675	656.35585	70.495	89.1945	73.1483	77.5549	76.8886	78.197	71.8443	77.773	615.0956
PC (diacyl 16:0/18:1)	68.5469	56.5765	72.0465	68.7111	63.2588	64.9644	73.013	78.5068	545.624	62.3469	67.2052	72.304	74.2758	59.8759	62.9609	72.5513	80.4307	551.9507	67.7311	51.0537	73.5605	69.7559	62.1768	63.967	74.3613	76.3778	538.9841	67.9205	48.3462	72.9415	68.9779	62.5884	63.9177	68.3297	79.0129	532.0348	66.3948	61.6668	68.8137	65.8954	59.2201	68.25	74.7667	74.2626	539.2701	64.639	55.7408	76.7047	72.0468	64.6095	68.3482	72.1328	83.7979	558.0197	74.0505	52.4787	82.9118	73.7199	71.5424	67.3506	86.0368	85.5712	593.6619	104.2847	94.0597	129.1246	132.6311	134.7658	125.9988	115.5606	119.1124	955.5377	63.8521	50.5048	77.7893	61.1249	62.0699	66.7228	72.4753	79.2522	533.7913	66.2621	48.9645	77.1843	63.7716	58.9502	61.8967	72.9547	87.3967	537.3808	87.9637	64.7632	104.0564	74.382	71.5069	74.4685	76.8728	84.2202	638.2337	70.5042	42.6607	77.9847	63.8529	58.6885	57.4471	71.2833	84.823	527.2444	68.0188	57.8119	77.6317	79.6702	64.72	65.3585	73.4117	76.3398	562.9626	73.3659	56.8118	77.4642	64.0545	59.6735	82.6074	80.5877	74.7885	569.3535	64.3032	51.3898	70.4397	64.5248	57.7826	60.5455	77.2386	77.0494	523.2736	67.1116	71.5308	82.5682	69.2681	60.4926	64.4848	67.7943	82.8124	566.0628	68.7261	68.9829	75.3746	89.3903	70.8196	64.01355	79.5573	68.8185	585.68285	58.5829	55.1537	74.7662	69.3758	66.289	63.5423	73.7724	70.786	532.2683
PC[(20:4/18:3)]/PC[(16:0/20:4)/(18:2/18:2)/(18:3/18:1)]	462.5296	200.9729	360.0532	406.1486	420.5758	404.7396	236.4632	254.1284	2745.6113	394.2455	200.2446	340.6801	376.4629	411.706	339.471	248.0694	263.622	2574.5015	426.5184	249.2836	344.1452	366.8078	427.7203	392.7265	207.8974	233.6968	2648.796	418.7631	201.4153	349.2221	361.3478	393.6233	357.6875	223.3947	241.782	2547.2358	440.4035	235.8446	351.0366	368.4355	399.5229	333.3288	224.5339	214.1615	2567.2673	457.0758	235.5239	330.604	368.9097	406.6885	370.1971	248.0062	268.8102	2685.8154	464.3939	218.7917	353.2957	426.8103	438.9191	424.3575	225.1116	269.5056	2821.1854	411.5136	200.2983	323.1165	410.7983	422.4694	400.3439	202.8786	254.1842	2625.6028	461.6261	254.4114	368.9918	462.3273	470.5172	376.8513	227.2107	293.6637	2915.5995	474.5717	250.4294	352.0446	456.8147	461.1499	459.4433	262.0135	282.7088	2999.1759	438.5475	248.0054	335.7101	453.08	451.9254	423.7322	245.8658	263.9176	2860.784	429.6869	210.617	337.383	415.1843	421.0402	385.3655	257.8674	281.3236	2738.4679	407.5111	244.6807	322.9612	364.5668	419.6249	399.3492	258.4042	266.652	2683.7501	436.3345	274.24	363.5506	415.9482	453.4064	305.7284	170.444	205.7173	2625.3694	415.6054	241.6122	356.2272	438.9062	463.5972	531.6794	197.8393	277.0307	2922.4976	330.038	262.1671	336.7313	391.0132	417.2725	391.8897	267.9354	282.4646	2679.5118	529.2257	337.394	388.1434	390.1661	470.2941	388.54115	296.4902	337.7021	3137.95675	512.8609	277.6736	394.91	426.6917	502.5329	385.1926	274.7194	336.8883	3111.4694
GalCer(d18:1/22:0)	138.969	81.2721	121.7767	121.6167	128.91	119.6949	85.1501	99.0532	896.4427	120.2123	78.4513	124.5497	118.323	126.9578	107.4848	91.2622	101.8457	869.0868	123.092	84.838	113.4604	107.4885	120.8707	113.5916	83.5548	95.1413	842.0373	125.7069	78.6994	119.141	111.4118	115.9918	109.8364	84.5078	99.4445	844.7396	125.158	83.2245	113.371	112.3803	115.4468	100.9403	82.8173	91.058	824.3962	129.5464	82.5863	110.0142	110.0413	117.8348	112.4666	81.3951	98.6357	842.5204	137.2559	87.1722	128.7041	135.7918	134.3691	130.1363	92.7728	107.063	953.2652	132.8526	77.2858	125.8912	135.5138	135.5315	125.6152	86.1738	107.4393	926.3032	135.8219	93.2767	131.0571	129.2064	126.0503	114.7469	89.0959	112.793	932.0482	133.4858	83.5682	119.9112	128.6133	124.7412	119.7759	92.0542	99.4767	901.6265	147.3663	101.2665	126.4019	130.7704	126.9632	128.4008	95.2561	109.8654	966.2906	133.0213	80.2534	121.7917	123.8573	120.4629	114.6379	89.1624	113.6096	896.7965	137.4345	88.8851	122.1397	125.731	138.4939	126.4437	98.051	109.5429	946.7218	156.1474	99.499	126.0222	133.3051	139.0538	125.3328	83.1603	99.3405	961.8611	129.3442	89.573	117.7774	125.4089	124.5929	146.5142	94.3506	114.5227	942.0839	111.7983	95.9821	126.9887	132.7195	138.8479	131.9811	94.9793	106.5998	939.8967	175.7726	126.7787	146.5998	128.2021	160.2214	131.6372	122.425	140.6657	1132.3025	141.5403	96.6317	127.6605	137.7787	149.8945	131.2933	94.2578	115.8157	994.8725
PC[(20:3/18:2)]/PC[(18:1/18:1)]	235.413	328.6361	224.3691	218.5568	254.2436	236.6165	282.6999	293.0766	2073.6116	273.6636	319.5397	220.7104	219.3527	249.3224	270.4578	264.7032	286.3282	2104.078	223.1101	310.8004	204.2268	189.54	216.3389	212.3344	274.7978	282.2206	1913.369	236.4425	353.1975	219.6711	214.8238	242.9277	255.5666	291.8299	282.5916	2097.0507	212.5318	291.3592	207.5879	221.0725	214.1707	233.9308	270.6771	294.8266	1946.1566	243.4872	337.3894	208.9125	201.3679	242.8649	239.765	281.8064	285.4998	2041.0931	236.1204	363.6758	225.0616	208.3715	224.3001	252.6158	296.3312	276.1928	2082.6692	255.9265	361.3978	226.4133	224.0235	235.2991	246.0501	311.1774	282.7689	2143.0566	253.5897	364.7801	233.3691	221.2115	218.5628	264.3144	289.9284	294.3016	2140.0576	245.1925	347.6853	232.0755	226.9887	257.0448	252.3354	324.3382	326.8661	2212.5265	236.2853	383.7519	226.1632	220.148	229.1454	267.0697	318.9613	296.784	2178.3088	228.8877	410.9187	215.0536	211.2703	232.9741	255.4369	287.5924	311.5874	2153.7211	224.1663	300.912	207.5291	205.729	220.1633	229.1251	249.3217	248.4895	1885.436	215.414	299.9092	198.1296	196.2601	195.0455	295.1064	262.8655	317.8629	1980.5932	228.5857	265.4256	188.2981	190.0374	197.714	223.9813	240.9672	230.6452	1765.6545	212.022	285.523	210.5606	215.0885	226.5272	234.355	287.1613	266.9264	1938.164	212.1832	255.8625	233.5712	175.5088	209.8656	281.18065	295.6958	319.3353	1983.20305	226.1057	343.4949	226.6363	251.9153	245.8534	328.0063	254.4797	300.4923	2176.9839
PC[(20:3/18:1)]/PC[(18:0/18:1)/(20:1/16:0)/(20:0/16:1)]	788.5493	1544.5793	761.9054	718.5062	815.458	810.107	1133.3839	1181.7958	7754.2849	1066.7797	1480.3535	723.9443	694.0014	783.441	1024.9615	1091.112	1124.2524	7988.8458	771.9514	1523.132	708.3675	684.9948	741.8262	718.519	1152.115	1193.4418	7494.3477	828.5097	1672.4691	734.1255	777.5304	804.5002	925.0125	1204.3513	1145.9001	8092.3988	749.3881	1358.6403	736.3792	749.3652	711.599	759.6323	1072.645	1246.1045	7383.7536	841.3061	1506.7401	745.4055	813.4619	869.7681	885.1696	1169.0685	1115.2033	7946.1231	758.0507	1585.3825	733.9603	671.9053	718.3765	874.6712	1124.0413	1100.3349	7566.7227	808.4815	1604.4198	731.5752	698.1964	739.0513	792.0542	1209.2311	1073.412	7656.4215	897.7783	1530.8046	766.4677	692.1942	760.1023	969.264	1180.4755	1135.0502	7932.1368	793.7688	1610.7814	762.1874	774.2065	817.0397	817.8325	1187.4476	1178.6815	7941.9454	747.8412	1538.0617	731.2323	686.9101	755.8525	783.8158	1186.3985	1116.4563	7546.5684	751.1824	1722.3027	725.3583	738.7626	762.0853	913.4011	1096.2423	1100.4889	7809.8236	682.487	1387.9567	656.0277	639.7039	714.566	745.0656	954.9801	999.8746	6780.6616	747.5226	1501.6831	668.8964	645.569	685.7136	1045.0821	1201.2643	1392.1461	7887.8772	735.1989	1628.6909	644.1995	608.0293	732.2624	811.3142	1134.3815	983.5658	7277.6425	800.5351	1227.5213	701.2704	675.8119	753.3027	755.7102	1029.8427	1095.7319	7039.7262	638.4705	1046.7691	672.3997	665.154	741.7685	902.49565	1073.5859	1103.4803	6844.12365	690.3168	1495.4888	700.0995	754.0205	789.5655	1049.2811	1034.6958	1121.8295	7635.2975
PC[(20:3/18:0)] / PC[(18:0/18:0)]	140.6912	283.7483	134.9042	128.6038	143.5919	141.7846	197.057	211.0997	1381.4807	187.5334	268.8351	126.2209	126.3283	135.6043	179.5352	187.1734	199.394	1410.6246	125.807	259.1285	113.7433	110.7209	116.6691	114.678	194.2121	205.9798	1240.9387	139.5746	294.3957	126.0572	130.3123	139.1202	160.4009	200.8542	198.1663	1388.8814	120.7432	232.3731	119.417	124.6595	111.3551	123.7365	180.2725	215.0703	1227.6272	143.5426	265.5892	125.4742	137.0688	149.7728	147.8897	196.418	197.8997	1363.655	137.322	285.2361	134.777	124.5916	132.8276	160.9412	200.2236	196.2512	1372.1703	145.5795	293.5327	133.933	130.3032	137.2506	146.646	221.9701	196.9452	1406.1603	149.3627	261.934	126.2739	109.8876	120.3275	155.069	187.0324	186.7608	1296.6479	143.4545	278.4486	135.6783	133.3748	138.4084	136.7517	207.448	211.2167	1384.781	135.8902	286.8279	130.3167	125.8493	135.2671	142.5535	223.1343	212.2049	1392.0439	127.4643	295.3553	123.3629	124.2031	120.7129	146.5383	184.0306	190.2782	1311.9456	114.3991	229.6176	113.6158	115.0938	118.3116	122.281	156.7553	164.4761	1134.5503	118.1392	235.4181	102.8189	98.9269	100.507	173.347	182.3821	212.0836	1223.6228	114.9558	215.3876	96.0416	94.7718	101.769	118.449	183.4981	159.9645	1084.8374	145.8816	224.981	130.0866	131.0964	136.6154	137.5585	184.225	193.4302	1283.8747	100.3329	161.1677	104.8707	109.6078	111.4437	146.0357	160.305	160.4039	1054.1674	96.2664	219.4703	103.8853	124.0624	116.7626	154.5129	140.8204	153.4599	1109.2402
PC (diacyl 18:1/18:3)	47.0326	47.3833	46.7961	53.4155	44.0381	44.7298	41.8599	40.6807	365.936	47.9271	47.9835	50.1802	47.7162	45.2007	46.0609	43.109	44.3943	372.5719	52.2943	41.9065	51.4135	54.6293	47.8921	52.6997	45.8267	42.7453	389.4074	53.8164	39.6943	53.1995	52.4633	49.1604	45.225	44.1596	45.756	383.4745	52.8866	44.7533	51.4409	52.9215	49.5889	47.4725	42.8395	39.883	381.7862	49.2796	41.3973	49.9928	51.0688	48.2063	46.2675	41.8257	43.6683	371.7063	54.6373	48.8076	57.0593	55.5532	55.2444	54.5487	46.1602	49.1231	421.1338	51.3473	50.7227	53.9011	60.3826	57.6887	55.979	43.714	46.74	420.4754	50.3519	43.9028	53.0469	53.3836	50.3517	49.915	44.6226	46.84	392.4145	45.3145	51.5761	48.5756	44.5054	41.344	42.808	46.649	46.1479	366.9205	56.1656	52.3989	55.0814	51.3694	52.6118	51.1941	42.3184	45.3698	406.5094	50.4758	39.449	50.9326	48.1543	45.0578	42.8922	43.452	43.7669	364.1806	59.6752	57.3297	57.3464	54.3799	54.31	54.1876	51.4184	55.4674	444.1146	57.4203	50.2521	54.7591	50.5689	50.3708	64.8136	64.8614	43.5346	436.5808	54.6678	50.9127	55.5599	57.7449	51.5649	59.7604	56.7971	54.4337	441.4414	49.0735	53.9045	51.9149	46.6221	44.6405	46.161	43.1827	46.5547	382.0539	60.5654	58.0508	60.9901	55.6282	56.349	46.6447	52.7536	50.7267	441.7085	50.4093	46.4665	54.7417	55.9442	54.0177	47.1284	49.2593	45.4471	403.4142
PC (diacyl 18:1/18:2)	39.4555	181.9017	42.448	44.113	37.3071	42.2122	71.0311	72.3779	530.8465	75.0919	170.4299	44.026	41.6894	41.3319	75.8606	64.8438	81.5286	594.8021	51.268	130.8086	46.0531	47.3149	44.5289	51.432	77.9452	80.7352	530.0859	56.5909	142.772	48.3409	48.4321	53.3596	55.4288	81.8761	83.5194	570.3198	52.1495	125.9246	49.2765	49.7378	44.9679	48.8259	76.1163	78.2566	525.2551	48.4178	120.9773	47.3873	49.7662	54.3137	50.9017	71.3959	80.7788	523.9387	50.8484	171.6936	56.3915	45.676	53.3729	75.8648	77.8297	79.134	610.8109	51.5669	193.9495	49.8017	46.8443	51.9768	60.4316	94.7003	84.9812	634.2523	55.7108	129.4085	46.1643	46.6966	54.1628	73.236	78.9146	74.069	558.3626	46.9755	195.2023	55.3602	41.6326	42.7882	46.9425	106.9643	98.0556	633.9212	52.9058	191.0594	52.1198	38.7224	53.2155	59.6555	83.8767	87.6433	619.1984	44.353	144.3586	47.4908	45.5939	42.6022	53.6169	66.9699	69.156	514.1413	67.0247	193.5936	63.0834	56.6645	59.6907	65.4722	81.6248	104.8588	692.0127	75.824	159.9686	46.5439	46.6922	51.7328	185.965	225.4026	85.4462	877.5753	62.7588	160.6836	52.9952	52.3431	57.815	74.9115	117.4467	80.0763	659.0302	58.5522	157.8084	44.9215	39.9021	46.6287	50.4275	73.2336	82.7461	554.2201	59.4325	160.8955	57.9624	57.5838	67.5145	68.22865	90.8241	90.0874	652.52885	58.8277	153.7698	68.3519	88.6472	71.7273	86.0298	98.5153	85.0277	710.8967
PC (diacyl 18:0/18:2)	62.9593	93.8992	69.3439	101.722	68.9862	72.634	80.5036	62.5222	612.5704	76.0379	92.1064	79.1678	83.0495	81.2591	79.8291	87.8477	69.4661	648.7636	121.0128	102.8311	126.5046	190.4999	131.2703	158.8099	118.3562	82.6621	1031.9469	127.3014	92.7794	128.1854	159.8609	99.882	85.6197	118.7579	93.5376	905.9243	136.8034	113.4008	140.6278	141.2522	162.0266	135.7846	99.015	74.5084	1003.4188	93.9293	87.8911	120.0618	141.9928	102.8853	94.8841	98.8759	77.7551	818.2754	94.1572	98.0264	111.5341	139.9559	125.1548	113.1457	96.144	85.9739	864.092	64.8516	98.6614	64.6435	95.8112	81.5963	86.1379	71.1362	65.0784	627.9165	105.5837	101.8992	118.2482	178.9658	145.5457	125.4359	114.2391	91.4842	981.4018	60.6363	93.3412	80.0402	90.5406	73.7481	75.9998	82.2325	62.4245	618.9632	87.5522	106.5129	84.4444	96.3897	101.6923	94.1774	67.7042	67.3306	705.8037	85.7561	83.9856	93.0764	111.814	112.1773	90.2484	87.7887	74.3516	739.1981	154.146	138.9057	142.7712	152.222	162.6093	149.0251	140.879	132.7919	1173.3502	140.512	125.5164	160.3991	204.6319	201.6974	143.626	175.1839	110.7408	1262.3075	171.8584	171.9929	184.6464	242.7192	208.7247	205.2168	168.8076	154.6773	1508.6433	91.1183	111.721	91.4355	97.1648	98.2842	97.9508	86.9656	87.8317	762.4719	176.446	149.1867	187.1542	159.0281	182.1848	104.29295	133.0591	124.4375	1215.78935	134.126	112.1696	138.6659	180.7605	145.74	110.6351	146.977	110.6242	1079.6983
GalCer(d18:1/24:1)	476.2706	318.4093	359.4672	417.0283	484.5427	431.8983	346.763	304.7501	3139.1295	446.2376	296.3524	327.6955	390.5055	464.168	387.9525	350.29	309.9953	2973.1968	438.444	346.9718	331.2786	360.2793	437.6836	400.196	333.0539	298.7509	2946.6581	426.2626	302.0703	343.6819	390.4956	429.3076	408.2371	326.344	291.9194	2918.3185	444.912	318.758	343.8168	410.1139	437.4598	388.4773	341.5229	290.2036	2975.2643	475.8433	331.8124	326.008	396.772	458.5677	418.7766	370.7034	314.6228	3093.1062	472.9388	327.3239	350.73	438.5433	482.3807	467.5505	340.0228	318.6706	3198.1606	449.5864	318.7606	308.1641	427.7357	437.8449	403.4218	316.9539	281.6992	2944.1666	495.0562	358.2043	357.4201	482.2243	496.6372	417.5318	347.5392	332.3096	3286.9227	484.2361	367.4567	345.0001	466.761	507.1557	478.2212	376.858	325.0754	3350.7642	449.3862	378.4477	324.2464	465.115	485.1129	460.2897	362.64	296.9121	3222.15	448.4723	320.5693	326.5171	437.6139	453.4675	425.614	373.5691	301.1238	3086.947	386.4712	333.5019	304.7067	343.3874	423.7561	410.1934	348.4727	289.2119	2839.7013	418.3329	367.5513	343.799	414.7088	468.4292	398.7786	289.8392	274.5128	2975.9518	418.45	330.6612	317.6662	422.1647	459.8068	511.3451	300.8773	273.7707	3034.742	364.5317	347.9754	323.7703	390.1806	440.0996	410.0824	377.2698	322.7149	2976.6247	435.5532	354.0887	354.7382	353.6025	441.1422	404.1123	366.7995	331.1143	3041.1509	417.7528	339.0211	338.0908	441.4918	491.4169	398.1422	384.7516	315.3448	3126.012
GalCer(d18:1/24:0)	111.3544	119.1828	94.7597	99.8904	110.2325	100.903	96.5834	97.3249	830.2311	111.7619	108.7038	90.5789	94.7238	104.8177	102.7973	98.4608	101.0289	812.8731	100.0317	104.5611	84.5401	85.9361	96.0819	90.7963	97.6357	98.4245	758.0074	103.9218	111.0654	93.6622	95.6726	103.339	103.0005	99.5266	102.4574	812.6455	99.0903	104.5708	88.0964	98.7732	93.6406	94.8356	92.9991	95.1345	767.1405	108.6083	106.0247	88.8845	96.9446	107.8693	100.9398	95.2106	98.3659	802.8477	112.2398	120.0008	101.9185	111.599	116.4706	118.5796	105.0305	105.1003	890.9391	111.2903	118.2978	93.1584	110.8954	110.9065	102.7812	105.3211	100.2834	852.9341	115.8119	118.7412	99.055	106.0562	109.4215	106.3237	102.1867	105.4289	863.0251	110.6871	122.1162	98.9138	116.2969	106.7169	107.9076	112.3385	100.2547	875.2317	122.128	141.7791	96.3858	109.8799	109.9979	113.7332	109.8213	107.8144	911.5396	109.5064	122.551	95.0191	108.1718	101.7015	109.2638	102.6961	106.0891	854.9988	97.4609	111.5034	89.5672	92.7674	103.2428	100.1377	97.5069	97.8804	790.0667	137.7497	129.8068	95.693	109.9831	111.9207	152.0529	127.5928	117.7386	982.5376	104.5089	113.7144	86.9905	92.315	96.7539	111.2608	111.7825	103.9242	821.2502	96.3179	116.0927	92.1995	101.8333	106.3257	104.9028	102.9049	103.9021	824.4789	111.0473	123.046	100.3244	97.8011	123.28	107.553	107.1209	109.0609	879.2336	94.2915	115.5968	92.994	120.946	116.1968	110.2032	104.3232	97.5911	852.1426
GalCer(d18:1/24:1h)	40.5277	92.0499	41.3048	49.5804	40.7618	40.2851	58.1702	62.1054	424.7853	56.8204	94.7681	44.8486	41.6161	41.5126	58.2823	59.4087	69.9226	467.1794	49.4525	68.2081	48.1093	47.5583	43.3654	49.9831	66.8922	68.4865	442.0554	49.4486	77.8134	47.2106	45.5605	48.1863	48.6645	65.7591	68.7807	451.4237	48.2386	67.6843	46.6568	50.2154	42.3944	42.5511	60.5165	64.9125	423.1696	44.7052	70.8552	45.9184	46.236	48.9919	48.9776	59.0334	63.7449	428.4626	53.3061	104.2774	58.0342	46.8147	55.3171	61.6069	69.8408	74.5869	523.7841	51.1123	108.0476	51.0718	53.1152	53.688	54.0849	76.6361	72.9753	520.7312	50.6432	74.9311	50.8709	48.3402	50.4038	55.853	66.5973	69.8105	467.45	49.5237	110.4625	52.2811	41.2858	46.9768	47.5416	81.3857	91.7693	521.2265	50.5812	99.2312	52.7225	48.3338	53.8696	51.4957	67.698	71.2294	495.1614	45.1394	84.025	46.0529	44.6199	43.1534	45.0017	61.187	64.493	433.6723	58.1106	99.5352	57.914	52.0437	54.7403	58.3885	68.0013	84.3165	533.0501	58.4548	84.5164	50.8986	44.338	46.7244	101.4678	128.5863	65.8042	580.7905	56.7781	88.7717	56.1493	59.4332	49.5724	62.416	100.0825	73.4036	546.6068	47.6893	83.1247	45.8617	40.7748	41.6042	44.5283	57.7132	66.8708	428.167	51.0128	82.3069	60.3435	57.2998	59.0631	56.62345	79.3978	75.2578	521.30515	48.5075	76.6734	59.4059	71.081	63.1865	68.7186	74.6716	69.252	531.4965
GalCer(d18:1/18:0)	50.8603	140.3064	64.235	83.627	54.786	62.3596	98.3124	89.6502	644.1369	79.41	137.1628	79.8361	69.1458	69.802	92.0017	109.3676	103.9045	740.6305	121.3246	144.4468	131.0413	175.2787	127.9754	154.4031	162.4005	128.0503	1144.9207	136.5961	140.2458	134.2551	158.3293	98.3021	89.673	182.1247	148.1395	1087.6656	136.0705	157.2825	145.6095	138.3091	156.1986	138.5487	133.9202	122.903	1128.8421	88.0152	126.998	124.165	138.5939	103.1333	101.3901	127.5638	109.3036	919.1629	90.7537	151.7758	117.6099	123.4684	108.0651	101.7331	139.4355	131.0262	963.8677	54.7732	133.2392	63.0922	74.1034	64.4099	72.099	92.6514	93.6652	648.0335	102.28	151.7178	125.9569	153.2187	130.5455	134.1515	171.8746	138.9502	1108.6952	50.4215	131.9332	84.1343	79.0975	63.5859	64.8625	109.9584	100.9434	684.9367	81.4516	143.3888	86.2224	69.9063	84.9989	76.827	82.7715	97.1215	722.688	73.519	125.8052	93.7418	97.5633	101.8117	89.9396	110.3716	112.2904	805.0426	165.4097	236.4955	156.9759	150.8318	177.759	171.5765	201.9453	232.0938	1493.0875	163.5847	193.4969	171.3039	193.5567	191.9498	187.8035	378.716	235.922	1716.3335	199.2919	360.8685	215.4694	232.3065	236.1708	225.3525	350.3143	299.1447	2118.9186	97.9519	168.7477	101.3299	89.3938	100.2224	108.0438	118.4798	151.3985	935.5678	194.3405	256.2397	220.7489	180.2061	246.0676	137.5374	236.516	227.7423	1699.3985	156.7813	201.8999	177.0995	206.0317	185.3291	167.031	247.9421	216.8521	1558.9667
TG(16:0/18:1/18:2)	26.3436	27.3891	25.021	26.3976	22.0033	24.2494	27.3002	25.1454	203.8496	22.4913	27.7107	22.0652	25.8886	21.3458	22.3471	24.0041	23.7159	189.5687	27.2508	22.8215	25.2982	31.1415	24.1021	28.4876	29.5597	24.2796	212.941	27.1791	22.2377	27.239	29.1563	25.5688	25.2637	26.2236	26.923	209.7912	27.7739	28.3496	24.777	28.5873	25.7933	32.9575	29.3368	22.7532	220.3286	23.0177	20.7261	26.0766	25.6688	21.6691	23.0344	23.7701	24.0889	188.0517	23.2182	23.5457	26.2399	26.1303	26.2543	26.0053	26.087	23.9231	201.4038	23.7945	20.7936	22.1362	27.5841	25.6591	26.6318	25.5719	24.4998	196.671	20.8621	22.6603	22.5248	27.1037	22.8504	21.4916	28.9957	22.9247	189.4133	17.9908	21.0685	20.9481	18.5451	15.8388	17.5626	22.6504	21.2013	155.8056	27.8977	23.7366	25.1869	23.2349	23.5876	27.4063	27.4606	25.5777	204.0883	26.0136	20.8976	21.1998	24.6016	19.927	21.2283	25.5932	25.1588	184.6199	32.3557	27.4952	31.0777	35.4522	25.5181	27.4773	32.0233	29.3183	240.7178	30.2423	23.9427	23.4383	22.755	21.603	40.7113	31.8545	22.6322	217.1793	20.1291	23.6606	18.6988	22.8513	18.6851	20.9312	23.9207	20.4948	169.3716	33.3525	32.6023	31.3581	32.3429	28.6428	32.6	30.2802	33.1076	254.2864	29.6839	32.383	23.9765	31.0553	25.1425	26.37805	24.0168	22.3864	215.02245	19.5853	21.24	20.8784	24.6644	20.955	20.1561	22.6936	20.5799	170.7527
Cerebroside(24:0)OH	18.1676	32.7913	18.6191	20.5569	15.493	17.5323	21.7533	24.9983	169.9118	20.6944	33.3487	18.8142	19.5705	16.1843	21.0049	20.9558	25.2589	175.8317	21.1384	26.1229	20.4473	23.9095	18.4425	21.1303	24.6523	24.668	180.5112	21.8371	34.0876	20.9672	21.1434	19.1432	18.6913	25.2513	27.6598	188.7809	21.0316	28.2728	20.4781	20.4157	18.4548	21.6535	22.3432	24.8314	177.4811	18.2467	27.5295	21.0533	21.7567	18.047	18.2148	21.7274	24.5463	171.1217	19.9534	33.0498	21.4374	18.9608	20.4153	21.8554	24.7793	25.4327	185.8841	16.2598	31.2006	18.1074	17.3644	17.3055	18.6504	23.6766	24.7481	167.3128	17.1436	29.3515	17.5221	18.1845	18.3366	20.5065	21.9403	23.7808	166.7659	15.7249	31.4343	18.1641	14.8178	13.9551	15.6493	23.1803	26.4854	159.4112	18.4335	33.1962	19.267	19.4915	20.954	21.6797	22.9408	26.5212	182.4839	16.507	26.5361	17.3282	15.9913	15.2927	16.0452	19.6761	23.765	151.1416	23.1716	31.0654	24.0674	25.2214	21.2881	21.7968	24.1769	27.4329	198.2205	23.0799	27.5339	19.5426	20.555	18.3538	30.4588	35.7941	26.745	202.0631	20.7287	31.6931	20.7044	22.8325	19.4466	24.2862	29.3374	26.0519	195.0808	19.2119	27.7882	19.5729	17.3844	15.361	17.1616	19.576	25.4282	161.4842	21.2013	31.5497	22.2064	23.95	22.209	20.78705	24.6918	26.3074	192.90265	19.391	35.0495	23.3735	24.458	20.8212	24.4125	24.9498	28.2532	200.7087
TG(16:0/20:4/18:1)	17.17	16.9306	18.0049	24.865	17.1161	19.0272	21.6008	16.9907	151.7053	18.1691	20.3134	19.4978	22.6469	19.3867	18.6922	24.0884	18.3274	161.1219	27.5364	27.0347	26.6943	36.1146	27.1187	31.7298	34.5013	23.509	234.2388	30.2595	22.5554	27.6945	35.0074	24.2574	21.1074	36.0247	28.3834	225.2897	28.8281	31.4776	27.7611	29.9886	29.5069	30.1264	28.3245	22.5084	228.5216	21.86	21.5422	26.3777	32.3467	23.6353	23.3295	27.9727	21.0727	198.1368	22.6313	24.5059	25.349	26.75	25.4107	24.6203	29.3251	25.6589	204.2512	15.7875	16.8976	16.166	20.2855	17.091	19.2029	17.2666	16.4216	139.1187	23.2005	32.4147	22.9248	30.0682	26.5168	29.1491	34.4877	26.9651	225.7269	14.0186	16.3659	18.2151	18.1185	15.1419	15.8315	20.668	16.1877	134.5472	21.5324	22.1499	19.9748	22.6728	22.8332	23.1041	17.088	17.9232	167.2784	19.1313	22.5365	20.3192	21.3711	21.3855	21.1145	24.4658	21.9138	172.2377	32.1607	46.8654	30.9294	32.9567	32.9811	32.2685	41.0562	39.4594	288.6774	39.2907	41.5318	30.2344	35.2053	32.5854	37.8069	59.962	58.7458	335.3623	38.422	105.522	34.5594	39.5063	39.5528	46.6667	77.4585	60.4632	442.1509	21.069	29.5578	20.3556	19.8773	19.1034	19.9686	24.3259	25.6949	179.9525	31.2121	50.1288	35.0494	35.075	40.8735	24.0838	43.4187	39.8472	299.6885	25.4288	37.5613	28.4259	35.4133	31.4483	28.199	44.5383	34.8296	265.8445
MS_METABOLITE_DATA_END
#METABOLITES
METABOLITES_START
metabolite_name	Quantified m/z
Cholesterol	369.4942
Hydroxycholesterol	431.4531
LPC(1-acyl 16:0)	496.2997
LPC(1-acyl 18:2)	520.4285
LPC(1-acyl 18:1)	522.2369
PC(diacyl 16:0/18:2)	524.3929
Cer(18:1/20:4)-OH	601.9736
SM(16:0)	703.4973
PC(16:1/14:0)	704.5115
PC(16:0/14:1)	706.5355
PC[(18:1/14:1)/(16:0/16:2)/(16:1/16:1)]	730.5175
PC(16:0/16:1)	732.6813
PC(16:0/16:0)	734.6776
PC[(18:3/16:0)] / PC[(16:0/16:0)]	756.6565
PC(18:2/16:0)	758.6622
PC(18:1/16:0)	760.6895
PC(18:0/16:0)	762.6632
SM(18:0)	769.588
PC(16:0/18:2)	780.6497
PC[(18:3/18:1)/(18:2/18:2)]/PC[(16:0/18:1)]	782.6689
PC[(18:2/18:1)/(16:0/20:3)]/PC[(16:0/18:0)]	784.6802
PC[(18:0/18:2)/(18:1/18:1)]	786.6866
PC(18:0/18:1)	788.693
PC (diacyl 16:0/18:2)	796.6518
PC (diacyl 16:0/18:1)	798.6408
PC[(20:4/18:3)]/PC[(16:0/20:4)/(18:2/18:2)/(18:3/18:1)]	804.6527
GalCer(d18:1/22:0)	806.2273
PC[(20:3/18:2)]/PC[(18:1/18:1)]	808.6812
PC[(20:3/18:1)]/PC[(18:0/18:1)/(20:1/16:0)/(20:0/16:1)]	810.6844
PC[(20:3/18:0)] / PC[(18:0/18:0)]	812.6954
PC (diacyl 18:1/18:3)	820.6161
PC (diacyl 18:1/18:2)	822.7349
PC (diacyl 18:0/18:2)	824.6467
GalCer(d18:1/24:1)	832.6703
GalCer(d18:1/24:0)	834.2897
GalCer(d18:1/24:1h)	848.6149
GalCer(d18:1/18:0)	850.7609
TG(16:0/18:1/18:2)	863.6331
Cerebroside(24:0)OH	866.6102
TG(16:0/20:4/18:1)	879.6133
METABOLITES_END
#END