MGP Database

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MGP002765

Ontology/Pathway Information

Entrez Gene ID6336
Gene Namesodium channel, voltage gated, type X alpha subunit
Gene Symbol SCN10A
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0044299 IEA:EnsemblCC-fiber
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0001518 IDA:BHF-UCLCvoltage-gated sodium channel complex
GO:0005248 IDA:BHF-UCLFvoltage-gated sodium channel activity
GO:0086067 IMP:BHF-UCLPAV node cell to bundle of His cell communication
GO:0086069 IMP:BHF-UCLPbundle of His cell to Purkinje myocyte communication
GO:0086010 IBA:GO_CentralPmembrane depolarization during action potential
GO:0019228 IBA:GO_CentralPneuronal action potential
GO:0060371 IMP:BHF-UCLPregulation of atrial cardiac muscle cell membrane depolarization
GO:0055117 IMP:BHF-UCLPregulation of cardiac muscle contraction
GO:0002027 IMP:BHF-UCLPregulation of heart rate
GO:0034765 IDA:BHF-UCLPregulation of ion transmembrane transport
GO:0007600 TAS:ProtIncPsensory perception
GO:0019233 IEA:InterProPsensory perception of pain
GO:0035725 IDA:BHF-UCLPsodium ion transmembrane transport
GO:0006814 TAS:ProtIncPsodium ion transport
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_18266Axon guidance
REACT_111045Developmental Biology
REACT_22266Interaction between L1 and Ankyrins
REACT_22205L1CAM interactions
SMP Pathway Links
SMP IDDescription
SMP006793-Methylthiofentanyl Action Pathway
SMP00413Alfentanil Action Pathway
SMP00685Alvimopan Action Pathway
SMP00674Anileridine Action Pathway
SMP00392Benzocaine Action Pathway
SMP00393Bupivacaine Action Pathway
SMP00684Buprenorphine Action Pathway
SMP00414Carfentanil Action Pathway
SMP00394Chloroprocaine Action Pathway
SMP00424Citalopram Action Pathway
SMP00395Cocaine Action Pathway
SMP00405Codeine Action Pathway
SMP00423Desipramine Action Pathway
SMP00676Dezocine Action Pathway
SMP00396Dibucaine Action Pathway
SMP00689Dihydromorphine Action Pathway
SMP00680Dimethylthiambutene Action Pathway
SMP00675Diphenoxylate Action Pathway
SMP00425Escitalopram Action Pathway
SMP00681Ethylmorphine Action Pathway
SMP00415Fentanyl Action Pathway
SMP00426Fluoxetine Action Pathway
SMP00407Heroin Action Pathway
SMP00411Hydrocodone Action Pathway
SMP00410Hydromorphone Action Pathway
SMP00422Imipramine Action Pathway
SMP00690Ketobemidone Action Pathway
SMP00683Levallorphan Action Pathway
SMP00397Levobupivacaine Action Pathway
SMP00677Levomethadyl Acetate Action Action Pathway
SMP00673Levorphanol Action Pathway
SMP00398Lidocaine (Local Anaesthetic) Action Pathway
SMP00620Lidocaine (Local Anaesthetic) Metabolism Pathway
SMP00399Mepivacaine Action Pathway
SMP00408Methadone Action Pathway
SMP00678Methadyl Acetate Action Pathway
SMP00406Morphine Action Pathway
SMP00691Nalbuphine Action Pathway
SMP00688Naloxone Action Pathway
SMP00687Naltrexone Action Pathway
SMP00431Nicotine Action Pathway
SMP00400Oxybuprocaine Action Pathway
SMP00409Oxycodone Action Pathway
SMP00412Oxymorphone Action Pathway
SMP00686Pentazocine Action Pathway
SMP00401Prilocaine Action Pathway
SMP00402Procaine Action Pathway
SMP00403Proparacaine Action Pathway
SMP00672Propoxyphene Action Pathway
SMP00416Remifentanil Action Pathway
SMP00404Ropivacaine Action Pathway
SMP00417Sufentanil Action Pathway
SMP00671Tramadol Action Action Pathway
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