#METABOLOMICS WORKBENCH mlafrano_20140711_9753371_mwtab.txt DATATRACK_ID:139 STUDY_ID:ST000107 ANALYSIS_ID:AN000177 PROJECT_ID:PR000046 VERSION 1 CREATED_ON 2016-09-17 #PROJECT PR:PROJECT_TITLE Metabolomic & lipidomic profiles in response to exogenous insulin & GLP-1 PR:PROJECT_TITLE during prolonged fasting PR:PROJECT_TYPE Timecourse PR:PROJECT_SUMMARY This application requests funding to access state-of-the-art metabolomics and PR:PROJECT_SUMMARY platforms at the NIH West Coast Metabolomics Center to analyze plasma samples PR:PROJECT_SUMMARY recent insulin and glucagon-like peptide-1 (GLP-1) infusion experiments PR:PROJECT_SUMMARY in prolong-fasted elephant seals. This suite of studies was designed to better PR:PROJECT_SUMMARY the mechanisms contributing to the onset of an insulin resistantlike condition PR:PROJECT_SUMMARY by prolonged food deprivation/starvation in mammals. Because elephant seals PR:PROJECT_SUMMARY evolved robust physiological mechanisms that have allowed them to naturally PR:PROJECT_SUMMARY such protracted bouts of fasting, they provide an ideal model to address our PR:PROJECT_SUMMARY hypothesis that increased lipid utilization late in the fast contributes to PR:PROJECT_SUMMARY resistance in elephant seals. Insulin resistance is a common consequence of PR:PROJECT_SUMMARY in mammals and, while the mechanisms by which it manifests are still unclear, a PR:PROJECT_SUMMARY shift favoring increased mobilization and utilization of lipids during PR:PROJECT_SUMMARY food deprivation may be a principal causative factor. Insulin resistance has a PR:PROJECT_SUMMARY connotation due to its association with obesity and diabetes among humans, but PR:PROJECT_SUMMARY has been suggested to be an adaptive response to food deprivation. PR:INSTITUTE University of California, Merced PR:DEPARTMENT School of Natural Sciences PR:LABORATORY Molecular and Cellular Biology, Natural Sciences PR:LAST_NAME Ortiz PR:FIRST_NAME Rudy PR:ADDRESS 5200 N. Lake Rd.; Merced, CA 95343 PR:EMAIL rortiz@ucmerced.edu PR:PHONE 209.228.2964 #STUDY ST:STUDY_TITLE Metabolomic and lipidomic profiles in response to exogenous insulin and GLP-1 ST:STUDY_TITLE during prolonged fasting ST:STUDY_TYPE Timecourse ST:STUDY_SUMMARY Seventeen northern elephant seal pups constituting four different cohorts at ST:STUDY_SUMMARY Nuevo State Reserve were studied at two post-weaning periods: early (1-2 wk ST:STUDY_SUMMARY weaning; n=5) and late (6-7 weeks post weaning; n=12). Study #1: Prior to each ST:STUDY_SUMMARY protocol, plasma U/kg). Following the infusion, blood samples were collected at ST:STUDY_SUMMARY determine the effects of prolonged fasting on peripheral insulin activity and ST:STUDY_SUMMARY samples were collected. Ten fasting seal pups (n=5 early, n=5 late) were ST:STUDY_SUMMARY (i.v.) with a mass-specific dose of insulin (0.065 U/kg). Following the ST:STUDY_SUMMARY blood samples were collected at 10, 30, 60, 90, and 120 minutes. Study #2: ST:STUDY_SUMMARY late-fasted seal pups were administered either a low (LDG; 10 pmol/kg; n=3) or ST:STUDY_SUMMARY (HDG; 100 pmol/kg; n=4) dose of GLP-1 immediately following a glucose bolus ST:STUDY_SUMMARY g/kg) (i.v.) infused within 2 mins. the infusions, blood samples were collected ST:STUDY_SUMMARY 10, 30, 60, 90, 120, and 150 minutes. ST:INSTITUTE University of California, Davis ST:DEPARTMENT Nutrition ST:LABORATORY Newman ST:LAST_NAME John ST:FIRST_NAME Newman ST:ADDRESS 430 W. Health Sciences Dr., Davis, CA 95616 ST:EMAIL john.newman@ars.usda.gov ST:PHONE +1-530-752-1009 ST:NUM_GROUPS 4 ST:TOTAL_SUBJECTS 5 #SUBJECT SU:SUBJECT_TYPE Animal SU:SUBJECT_SPECIES Mirounga angustirostris SU:TAXONOMY_ID 9716 SU:SPECIES_GROUP Mammal #SUBJECT_SAMPLE_FACTORS: SUBJECT(optional)[tab]SAMPLE[tab]FACTORS(NAME:VALUE pairs separated by |)[tab]Additional sample data SUBJECT_SAMPLE_FACTORS - IE01-0 Treatment:Early ITT Infusion Study | Timepoint:0 mins SUBJECT_SAMPLE_FACTORS - IE02-0 Treatment:Early ITT Infusion Study | Timepoint:0 mins SUBJECT_SAMPLE_FACTORS - IE03-0 Treatment:Early ITT Infusion Study | Timepoint:0 mins SUBJECT_SAMPLE_FACTORS - IE04-0 Treatment:Early ITT Infusion Study | Timepoint:0 mins SUBJECT_SAMPLE_FACTORS - IE05-0 Treatment:Early ITT Infusion Study | Timepoint:0 mins SUBJECT_SAMPLE_FACTORS - IE01-10 Treatment:Early ITT Infusion Study | Timepoint:10 mins SUBJECT_SAMPLE_FACTORS - IE02-10 Treatment:Early ITT Infusion Study | Timepoint:10 mins SUBJECT_SAMPLE_FACTORS - IE03-10 Treatment:Early ITT Infusion Study | Timepoint:10 mins SUBJECT_SAMPLE_FACTORS - IE04-10 Treatment:Early ITT Infusion Study | Timepoint:10 mins SUBJECT_SAMPLE_FACTORS - IE05-10 Treatment:Early ITT Infusion Study | Timepoint:10 mins SUBJECT_SAMPLE_FACTORS - IE01-120 Treatment:Early ITT Infusion Study | Timepoint:120 mins SUBJECT_SAMPLE_FACTORS - IE02-120 Treatment:Early ITT Infusion Study | Timepoint:120 mins SUBJECT_SAMPLE_FACTORS - IE03-120 Treatment:Early ITT Infusion Study | Timepoint:120 mins SUBJECT_SAMPLE_FACTORS - IE04-120 Treatment:Early ITT Infusion Study | Timepoint:120 mins SUBJECT_SAMPLE_FACTORS - IE05-120 Treatment:Early ITT Infusion Study | Timepoint:120 mins SUBJECT_SAMPLE_FACTORS - IE01-30 Treatment:Early ITT Infusion Study | Timepoint:30 mins SUBJECT_SAMPLE_FACTORS - IE02-30 Treatment:Early ITT Infusion Study | Timepoint:30 mins SUBJECT_SAMPLE_FACTORS - IE03-30 Treatment:Early ITT Infusion Study | Timepoint:30 mins SUBJECT_SAMPLE_FACTORS - IE04-30 Treatment:Early ITT Infusion Study | Timepoint:30 mins SUBJECT_SAMPLE_FACTORS - IE05-30 Treatment:Early ITT Infusion Study | Timepoint:30 mins SUBJECT_SAMPLE_FACTORS - IE01-60 Treatment:Early ITT Infusion Study | Timepoint:60 mins SUBJECT_SAMPLE_FACTORS - IE02-60 Treatment:Early ITT Infusion Study | Timepoint:60 mins SUBJECT_SAMPLE_FACTORS - IE03-60 Treatment:Early ITT Infusion Study | Timepoint:60 mins SUBJECT_SAMPLE_FACTORS - IE04-60 Treatment:Early ITT Infusion Study | Timepoint:60 mins SUBJECT_SAMPLE_FACTORS - A01-0 Treatment:GLP1/Late GTT | Timepoint:0 mins SUBJECT_SAMPLE_FACTORS - A02-0 Treatment:GLP1/Late GTT | Timepoint:0 mins SUBJECT_SAMPLE_FACTORS - A03-0 Treatment:GLP1/Late GTT | Timepoint:0 mins SUBJECT_SAMPLE_FACTORS - A04-0 Treatment:GLP1/Late GTT | Timepoint:0 mins SUBJECT_SAMPLE_FACTORS - A05-0 Treatment:GLP1/Late GTT | Timepoint:0 mins SUBJECT_SAMPLE_FACTORS - B01-0 Treatment:GLP1/Late GTT | Timepoint:0 mins SUBJECT_SAMPLE_FACTORS - B02-0 Treatment:GLP1/Late GTT | Timepoint:0 mins SUBJECT_SAMPLE_FACTORS - B03-0 Treatment:GLP1/Late GTT | Timepoint:0 mins SUBJECT_SAMPLE_FACTORS - C01-0 Treatment:GLP1/Late GTT | Timepoint:0 mins SUBJECT_SAMPLE_FACTORS - C02-0 Treatment:GLP1/Late GTT | Timepoint:0 mins SUBJECT_SAMPLE_FACTORS - C03-0 Treatment:GLP1/Late GTT | Timepoint:0 mins SUBJECT_SAMPLE_FACTORS - C04-0 Treatment:GLP1/Late GTT | Timepoint:0 mins SUBJECT_SAMPLE_FACTORS - A01-10 Treatment:GLP1/Late GTT | Timepoint:10 mins SUBJECT_SAMPLE_FACTORS - A02-10 Treatment:GLP1/Late GTT | Timepoint:10 mins SUBJECT_SAMPLE_FACTORS - A03-10 Treatment:GLP1/Late GTT | Timepoint:10 mins SUBJECT_SAMPLE_FACTORS - A04-10 Treatment:GLP1/Late GTT | Timepoint:10 mins SUBJECT_SAMPLE_FACTORS - A05-10 Treatment:GLP1/Late GTT | Timepoint:10 mins SUBJECT_SAMPLE_FACTORS - B01-10 Treatment:GLP1/Late GTT | Timepoint:10 mins SUBJECT_SAMPLE_FACTORS - B02-10 Treatment:GLP1/Late GTT | Timepoint:10 mins SUBJECT_SAMPLE_FACTORS - B03-10 Treatment:GLP1/Late GTT | Timepoint:10 mins SUBJECT_SAMPLE_FACTORS - C01-10 Treatment:GLP1/Late GTT | Timepoint:10 mins SUBJECT_SAMPLE_FACTORS - C02-10 Treatment:GLP1/Late GTT | Timepoint:10 mins SUBJECT_SAMPLE_FACTORS - C03-10 Treatment:GLP1/Late GTT | Timepoint:10 mins SUBJECT_SAMPLE_FACTORS - C04-10 Treatment:GLP1/Late GTT | Timepoint:10 mins SUBJECT_SAMPLE_FACTORS - A01-120 Treatment:GLP1/Late GTT | Timepoint:120 mins SUBJECT_SAMPLE_FACTORS - A02-120 Treatment:GLP1/Late GTT | Timepoint:120 mins SUBJECT_SAMPLE_FACTORS - A03-120 Treatment:GLP1/Late GTT | Timepoint:120 mins SUBJECT_SAMPLE_FACTORS - A04-120 Treatment:GLP1/Late GTT | Timepoint:120 mins SUBJECT_SAMPLE_FACTORS - A05-120 Treatment:GLP1/Late GTT | Timepoint:120 mins SUBJECT_SAMPLE_FACTORS - B01-120 Treatment:GLP1/Late GTT | Timepoint:120 mins SUBJECT_SAMPLE_FACTORS - B02-120 Treatment:GLP1/Late GTT | Timepoint:120 mins SUBJECT_SAMPLE_FACTORS - B03-120 Treatment:GLP1/Late GTT | Timepoint:120 mins SUBJECT_SAMPLE_FACTORS - C01-120 Treatment:GLP1/Late GTT | Timepoint:120 mins SUBJECT_SAMPLE_FACTORS - C02-120 Treatment:GLP1/Late GTT | Timepoint:120 mins SUBJECT_SAMPLE_FACTORS - C03-120 Treatment:GLP1/Late GTT | Timepoint:120 mins SUBJECT_SAMPLE_FACTORS - C04-120 Treatment:GLP1/Late GTT | Timepoint:120 mins SUBJECT_SAMPLE_FACTORS - A01-30 Treatment:GLP1/Late GTT | Timepoint:30 mins SUBJECT_SAMPLE_FACTORS - A02-30 Treatment:GLP1/Late GTT | Timepoint:30 mins SUBJECT_SAMPLE_FACTORS - A03-30 Treatment:GLP1/Late GTT | Timepoint:30 mins SUBJECT_SAMPLE_FACTORS - A04-30 Treatment:GLP1/Late GTT | Timepoint:30 mins SUBJECT_SAMPLE_FACTORS - A05-30 Treatment:GLP1/Late GTT | Timepoint:30 mins SUBJECT_SAMPLE_FACTORS - B01-30 Treatment:GLP1/Late GTT | Timepoint:30 mins SUBJECT_SAMPLE_FACTORS - B02-30 Treatment:GLP1/Late GTT | Timepoint:30 mins SUBJECT_SAMPLE_FACTORS - B03-30 Treatment:GLP1/Late GTT | Timepoint:30 mins SUBJECT_SAMPLE_FACTORS - C01-30 Treatment:GLP1/Late GTT | Timepoint:30 mins SUBJECT_SAMPLE_FACTORS - C02-30 Treatment:GLP1/Late GTT | Timepoint:30 mins SUBJECT_SAMPLE_FACTORS - C03-30 Treatment:GLP1/Late GTT | Timepoint:30 mins SUBJECT_SAMPLE_FACTORS - C04-30 Treatment:GLP1/Late GTT | Timepoint:30 mins SUBJECT_SAMPLE_FACTORS - A01-60 Treatment:GLP1/Late GTT | Timepoint:60 mins SUBJECT_SAMPLE_FACTORS - A02-60 Treatment:GLP1/Late GTT | Timepoint:60 mins SUBJECT_SAMPLE_FACTORS - A03-60 Treatment:GLP1/Late GTT | Timepoint:60 mins SUBJECT_SAMPLE_FACTORS - A04-60 Treatment:GLP1/Late GTT | Timepoint:60 mins SUBJECT_SAMPLE_FACTORS - A05-60 Treatment:GLP1/Late GTT | Timepoint:60 mins SUBJECT_SAMPLE_FACTORS - B01-60 Treatment:GLP1/Late GTT | Timepoint:60 mins SUBJECT_SAMPLE_FACTORS - B02-60 Treatment:GLP1/Late GTT | Timepoint:60 mins SUBJECT_SAMPLE_FACTORS - B03-60 Treatment:GLP1/Late GTT | Timepoint:60 mins SUBJECT_SAMPLE_FACTORS - C01-60 Treatment:GLP1/Late GTT | Timepoint:60 mins SUBJECT_SAMPLE_FACTORS - C02-60 Treatment:GLP1/Late GTT | Timepoint:60 mins SUBJECT_SAMPLE_FACTORS - C03-60 Treatment:GLP1/Late GTT | Timepoint:60 mins SUBJECT_SAMPLE_FACTORS - C04-60 Treatment:GLP1/Late GTT | Timepoint:60 mins SUBJECT_SAMPLE_FACTORS - IL01-0 Treatment:Late ITT Infusion Study | Timepoint:0 mins SUBJECT_SAMPLE_FACTORS - IL02-0 Treatment:Late ITT Infusion Study | Timepoint:0 mins SUBJECT_SAMPLE_FACTORS - IL03-0 Treatment:Late ITT Infusion Study | Timepoint:0 mins SUBJECT_SAMPLE_FACTORS - IL04-0 Treatment:Late ITT Infusion Study | Timepoint:0 mins SUBJECT_SAMPLE_FACTORS - IL05-0 Treatment:Late ITT Infusion Study | Timepoint:0 mins SUBJECT_SAMPLE_FACTORS - IL01-10 Treatment:Late ITT Infusion Study | Timepoint:10 mins SUBJECT_SAMPLE_FACTORS - IL02-10 Treatment:Late ITT Infusion Study | Timepoint:10 mins SUBJECT_SAMPLE_FACTORS - IL03-10 Treatment:Late ITT Infusion Study | Timepoint:10 mins SUBJECT_SAMPLE_FACTORS - IL04-10 Treatment:Late ITT Infusion Study | Timepoint:10 mins SUBJECT_SAMPLE_FACTORS - IL05-10 Treatment:Late ITT Infusion Study | Timepoint:10 mins SUBJECT_SAMPLE_FACTORS - IL01-120 Treatment:Late ITT Infusion Study | Timepoint:120 mins SUBJECT_SAMPLE_FACTORS - IL02-120 Treatment:Late ITT Infusion Study | Timepoint:120 mins SUBJECT_SAMPLE_FACTORS - IL03-120 Treatment:Late ITT Infusion Study | Timepoint:120 mins SUBJECT_SAMPLE_FACTORS - IL04-120 Treatment:Late ITT Infusion Study | Timepoint:120 mins SUBJECT_SAMPLE_FACTORS - IL05-120 Treatment:Late ITT Infusion Study | Timepoint:120 mins SUBJECT_SAMPLE_FACTORS - IL01-30 Treatment:Late ITT Infusion Study | Timepoint:30 mins SUBJECT_SAMPLE_FACTORS - IL02-30 Treatment:Late ITT Infusion Study | Timepoint:30 mins SUBJECT_SAMPLE_FACTORS - IL03-30 Treatment:Late ITT Infusion Study | Timepoint:30 mins SUBJECT_SAMPLE_FACTORS - IL04-30 Treatment:Late ITT Infusion Study | Timepoint:30 mins SUBJECT_SAMPLE_FACTORS - IL05-30 Treatment:Late ITT Infusion Study | Timepoint:30 mins SUBJECT_SAMPLE_FACTORS - IL01-60 Treatment:Late ITT Infusion Study | Timepoint:60 mins SUBJECT_SAMPLE_FACTORS - IL02-60 Treatment:Late ITT Infusion Study | Timepoint:60 mins SUBJECT_SAMPLE_FACTORS - IL03-60 Treatment:Late ITT Infusion Study | Timepoint:60 mins SUBJECT_SAMPLE_FACTORS - IL04-60 Treatment:Late ITT Infusion Study | Timepoint:60 mins #COLLECTION CO:COLLECTION_SUMMARY Following the GLP-1 or insulin infusion, blood samples were collected at 10, CO:COLLECTION_SUMMARY 60, 90, and 120 minutes. CO:COLLECTION_PROTOCOL_FILENAME Newman_Lab-Endocannabinoid_Extraction_Analysis_Protocol-Ortiz_WCMC.pdf;Newman_Lab_NEFA_SOPs-Ortiz_WCMC_Pilot.pdf CO:SAMPLE_TYPE Blood CO:COLLECTION_TIME 10, 30, 60, 90, and 120 minutes postprandial CO:STORAGE_CONDITIONS -80 C CO:BLOOD_SERUM_OR_PLASMA Plasma #TREATMENT TR:TREATMENT_SUMMARY Seventeen northern elephant seal pups constituting four different cohorts at TR:TREATMENT_SUMMARY Nuevo State Reserve were studied at two post-weaning periods: early (1-2 wk TR:TREATMENT_SUMMARY weaning; n=5) and late (6-7 weeks post weaning; n=12). Study #1: Prior to each TR:TREATMENT_SUMMARY protocol, plasma U/kg). Following the infusion, blood samples were collected at TR:TREATMENT_SUMMARY determine the effects of prolonged fasting on peripheral insulin activity and TR:TREATMENT_SUMMARY samples were collected. Ten fasting seal pups (n=5 early, n=5 late) were TR:TREATMENT_SUMMARY (i.v.) with a mass-specific dose of insulin (0.065 U/kg). Following the TR:TREATMENT_SUMMARY blood samples were collected at 10, 30, 60, 90, and 120 minutes. Study #2: TR:TREATMENT_SUMMARY late-fasted seal pups were administered either a low (LDG; 10 pmol/kg; n=3) or TR:TREATMENT_SUMMARY (HDG; 100 pmol/kg; n=4) dose of GLP-1 immediately following a glucose bolus TR:TREATMENT_SUMMARY g/kg) (i.v.) infused within 2 mins. the infusions, blood samples were collected TR:TREATMENT_SUMMARY 10, 30, 60, 90, 120, and 150 minutes. TR:TREATMENT_PROTOCOL_FILENAME Newman_Lab-Endocannabinoid_Extraction_Analysis_Protocol-Ortiz_WCMC.pdf;Newman_Lab_NEFA_SOPs-Ortiz_WCMC_Pilot.pdf TR:TREATMENT_COMPOUND GLP-1 or Insulin TR:TREATMENT_ROUTE Infusion TR:TREATMENT_DOSE low (10 pmol/kg) or high (100 pmol/kg) dose of GLP-1, insulin (0.065 U/kg) TR:ANIMAL_FASTING Yes, for insulin study #SAMPLEPREP SP:SAMPLEPREP_SUMMARY - SP:SAMPLEPREP_PROTOCOL_FILENAME Newman_Lab-Endocannabinoid_Extraction_Analysis_Protocol-Ortiz_WCMC.pdf;Newman_Lab_NEFA_SOPs-Ortiz_WCMC_Pilot.pdf SP:PROCESSING_STORAGE_CONDITIONS - 20 °C SP:EXTRACTION_METHOD SPE SP:EXTRACT_CLEANUP SPE SP:EXTRACT_STORAGE - 20 °C SP:SAMPLE_RESUSPENSION 100 µL SP:SAMPLE_SPIKING See sample prep protocol file #CHROMATOGRAPHY CH:CHROMATOGRAPHY_TYPE GC CH:INSTRUMENT_NAME - CH:COLUMN_NAME - CH:METHODS_FILENAME Newman_Lab-Endocannabinoid_Extraction_Analysis_Protocol-Ortiz_WCMC.pdf;Newman_Lab_NEFA_SOPs-Ortiz_WCMC_Pilot.pdf CH:COLUMN_TEMPERATURE 60 C CH:FLOW_GRADIENT See protocol/methods file CH:FLOW_RATE 0.25 CH:INTERNAL_STANDARD See protocol/methods file CH:RETENTION_TIME See protocol/methods file CH:SAMPLE_INJECTION 5 L CH:SOLVENT_A 0.1% acetic acid CH:SOLVENT_B 90% ACN / 10% IPA CH:ANALYTICAL_TIME 11 min CH:WEAK_WASH_SOLVENT_NAME 20% methanol, 10% isopropanol CH:WEAK_WASH_VOLUME 600 L CH:STRONG_WASH_SOLVENT_NAME 50:50 Acetonitrile:Methanol CH:STRONG_WASH_VOLUME 600 L CH:SAMPLE_LOOP_SIZE 17 L #ANALYSIS AN:ANALYSIS_TYPE MS AN:LABORATORY_NAME Newman AN:ACQUISITION_DATE 1/27/14, 1/29/14, 1/31/14, 2/4/14, 2/5/14, 2/7/14, AN:SOFTWARE_VERSION AB Sciex Analyst version 1.6.2 AN:OPERATOR_NAME Michael La Frano AN:DETECTOR_TYPE API 4000 QTrap (AB Sciex, Framingham, MA, USA) AN:DATA_FORMAT .mzML #MS MS:INSTRUMENT_NAME ABI Sciex API 4000 QTrap MS:INSTRUMENT_TYPE Triple quadrupole MS:MS_TYPE ESI MS:ION_MODE POSITIVE MS:MS_COMMENTS LC/MS MS:ION_SOURCE_TEMPERATURE See protocol/methods file MS:ION_SPRAY_VOLTAGE See protocol/methods file MS:MS_COMMENTS LC/MS #MS_METABOLITE_DATA MS_METABOLITE_DATA:UNITS nM MS_METABOLITE_DATA_START Samples IE01-0 IE02-0 IE03-0 IE04-0 IE05-0 IE01-10 IE02-10 IE03-10 IE04-10 IE05-10 IE01-120 IE02-120 IE03-120 IE04-120 IE05-120 IE01-30 IE02-30 IE03-30 IE04-30 IE05-30 IE01-60 IE02-60 IE03-60 IE04-60 A01-0 A02-0 A03-0 A04-0 A05-0 B01-0 B02-0 B03-0 C01-0 C02-0 C03-0 C04-0 A01-10 A02-10 A03-10 A04-10 A05-10 B01-10 B02-10 B03-10 C01-10 C02-10 C03-10 C04-10 A01-120 A02-120 A03-120 A04-120 A05-120 B01-120 B02-120 B03-120 C01-120 C02-120 C03-120 C04-120 A01-30 A02-30 A03-30 A04-30 A05-30 B01-30 B02-30 B03-30 C01-30 C02-30 C03-30 C04-30 A01-60 A02-60 A03-60 A04-60 A05-60 B01-60 B02-60 B03-60 C01-60 C02-60 C03-60 C04-60 IL01-0 IL02-0 IL03-0 IL04-0 IL05-0 IL01-10 IL02-10 IL03-10 IL04-10 IL05-10 IL01-120 IL02-120 IL03-120 IL04-120 IL05-120 IL01-30 IL02-30 IL03-30 IL04-30 IL05-30 IL01-60 IL02-60 IL03-60 IL04-60 Factors Treatment:Early ITT Infusion Study | Timepoint:0 mins Treatment:Early ITT Infusion Study | Timepoint:0 mins Treatment:Early ITT Infusion Study | Timepoint:0 mins Treatment:Early ITT Infusion Study | Timepoint:0 mins Treatment:Early ITT Infusion Study | Timepoint:0 mins Treatment:Early ITT Infusion Study | Timepoint:10 mins Treatment:Early ITT Infusion Study | Timepoint:10 mins Treatment:Early ITT Infusion Study | Timepoint:10 mins Treatment:Early ITT Infusion Study | Timepoint:10 mins Treatment:Early ITT Infusion Study | Timepoint:10 mins Treatment:Early ITT Infusion Study | Timepoint:120 mins Treatment:Early ITT Infusion Study | Timepoint:120 mins Treatment:Early ITT Infusion Study | Timepoint:120 mins Treatment:Early ITT Infusion Study | Timepoint:120 mins Treatment:Early ITT Infusion Study | Timepoint:120 mins Treatment:Early ITT Infusion Study | Timepoint:30 mins Treatment:Early ITT Infusion Study | Timepoint:30 mins Treatment:Early ITT Infusion Study | Timepoint:30 mins Treatment:Early ITT Infusion Study | Timepoint:30 mins Treatment:Early ITT Infusion Study | Timepoint:30 mins Treatment:Early ITT Infusion Study | Timepoint:60 mins Treatment:Early ITT Infusion Study | Timepoint:60 mins Treatment:Early ITT Infusion Study | Timepoint:60 mins Treatment:Early ITT Infusion Study | Timepoint:60 mins Treatment:GLP1/Late GTT | Timepoint:0 mins Treatment:GLP1/Late GTT | Timepoint:0 mins Treatment:GLP1/Late GTT | Timepoint:0 mins Treatment:GLP1/Late GTT | Timepoint:0 mins Treatment:GLP1/Late GTT | Timepoint:0 mins Treatment:GLP1/Late GTT | Timepoint:0 mins Treatment:GLP1/Late GTT | Timepoint:0 mins Treatment:GLP1/Late GTT | Timepoint:0 mins Treatment:GLP1/Late GTT | Timepoint:0 mins Treatment:GLP1/Late GTT | Timepoint:0 mins Treatment:GLP1/Late GTT | Timepoint:0 mins Treatment:GLP1/Late GTT | Timepoint:0 mins Treatment:GLP1/Late GTT | Timepoint:10 mins Treatment:GLP1/Late GTT | Timepoint:10 mins Treatment:GLP1/Late GTT | Timepoint:10 mins Treatment:GLP1/Late GTT | Timepoint:10 mins Treatment:GLP1/Late GTT | Timepoint:10 mins Treatment:GLP1/Late GTT | Timepoint:10 mins Treatment:GLP1/Late GTT | Timepoint:10 mins Treatment:GLP1/Late GTT | Timepoint:10 mins Treatment:GLP1/Late GTT | Timepoint:10 mins Treatment:GLP1/Late GTT | Timepoint:10 mins Treatment:GLP1/Late GTT | Timepoint:10 mins Treatment:GLP1/Late GTT | Timepoint:10 mins Treatment:GLP1/Late GTT | Timepoint:120 mins Treatment:GLP1/Late GTT | Timepoint:120 mins Treatment:GLP1/Late GTT | Timepoint:120 mins Treatment:GLP1/Late GTT | Timepoint:120 mins Treatment:GLP1/Late GTT | Timepoint:120 mins Treatment:GLP1/Late GTT | Timepoint:120 mins Treatment:GLP1/Late GTT | Timepoint:120 mins Treatment:GLP1/Late GTT | Timepoint:120 mins Treatment:GLP1/Late GTT | Timepoint:120 mins Treatment:GLP1/Late GTT | Timepoint:120 mins Treatment:GLP1/Late GTT | Timepoint:120 mins Treatment:GLP1/Late GTT | Timepoint:120 mins Treatment:GLP1/Late GTT | Timepoint:30 mins Treatment:GLP1/Late GTT | Timepoint:30 mins Treatment:GLP1/Late GTT | Timepoint:30 mins Treatment:GLP1/Late GTT | Timepoint:30 mins Treatment:GLP1/Late GTT | Timepoint:30 mins Treatment:GLP1/Late GTT | Timepoint:30 mins Treatment:GLP1/Late GTT | Timepoint:30 mins Treatment:GLP1/Late GTT | Timepoint:30 mins Treatment:GLP1/Late GTT | Timepoint:30 mins Treatment:GLP1/Late GTT | Timepoint:30 mins Treatment:GLP1/Late GTT | Timepoint:30 mins Treatment:GLP1/Late GTT | Timepoint:30 mins Treatment:GLP1/Late GTT | Timepoint:60 mins Treatment:GLP1/Late GTT | Timepoint:60 mins Treatment:GLP1/Late GTT | Timepoint:60 mins Treatment:GLP1/Late GTT | Timepoint:60 mins Treatment:GLP1/Late GTT | Timepoint:60 mins Treatment:GLP1/Late GTT | Timepoint:60 mins Treatment:GLP1/Late GTT | Timepoint:60 mins Treatment:GLP1/Late GTT | Timepoint:60 mins Treatment:GLP1/Late GTT | Timepoint:60 mins Treatment:GLP1/Late GTT | Timepoint:60 mins Treatment:GLP1/Late GTT | Timepoint:60 mins Treatment:GLP1/Late GTT | Timepoint:60 mins Treatment:Late ITT Infusion Study | Timepoint:0 mins Treatment:Late ITT Infusion Study | Timepoint:0 mins Treatment:Late ITT Infusion Study | Timepoint:0 mins Treatment:Late ITT Infusion Study | Timepoint:0 mins Treatment:Late ITT Infusion Study | Timepoint:0 mins Treatment:Late ITT Infusion Study | Timepoint:10 mins Treatment:Late ITT Infusion Study | Timepoint:10 mins Treatment:Late ITT Infusion Study | Timepoint:10 mins Treatment:Late ITT Infusion Study | Timepoint:10 mins Treatment:Late ITT Infusion Study | Timepoint:10 mins Treatment:Late ITT Infusion Study | Timepoint:120 mins Treatment:Late ITT Infusion Study | Timepoint:120 mins Treatment:Late ITT Infusion Study | Timepoint:120 mins Treatment:Late ITT Infusion Study | Timepoint:120 mins Treatment:Late ITT Infusion Study | Timepoint:120 mins Treatment:Late ITT Infusion Study | Timepoint:30 mins Treatment:Late ITT Infusion Study | Timepoint:30 mins Treatment:Late ITT Infusion Study | Timepoint:30 mins Treatment:Late ITT Infusion Study | Timepoint:30 mins Treatment:Late ITT Infusion Study | Timepoint:30 mins Treatment:Late ITT Infusion Study | Timepoint:60 mins Treatment:Late ITT Infusion Study | Timepoint:60 mins Treatment:Late ITT Infusion Study | Timepoint:60 mins Treatment:Late ITT Infusion Study | Timepoint:60 mins 1-Arachidonoyl Glycerol 12.0000 5.8700 8.1800 29.6000 13.9000 12.1000 7.7300 6.3700 12.9000 8.2800 7.6400 4.5000 21.6000 27.9000 23.4500 12.2000 5.5800 5.4000 21.3000 31.7000 14.5000 8.8900 24.9000 20.1000 21.7000 15.6000 9.3800 39.9000 5.4600 8.0700 4.0200 4.4100 9.1400 12.2000 14.1000 16.4000 6.9300 7.5500 9.7100 6.5000 11.9000 3.7400 2.5000 3.2500 9.4700 5.6700 18.8000 1.4000 6.4300 8.3400 6.5600 8.4850 15.9000 15.8000 7.2400 3.2300 6.5600 19.4000 5.5500 13.3000 5.2800 10.1000 3.3500 3.9300 6.4100 4.0000 9.2000 2.5300 4.6000 10.8000 5.2300 16.8000 7.7700 10.5000 6.6300 5.9800 6.0200 5.7200 7.3500 7.7100 5.2400 3.8600 6.7200 9.2900 14.7000 31.6000 5.0200 13.0000 23.3000 3.7500 9.3700 8.7600 13.0000 14.7000 11.5000 23.8000 9.1000 41.5000 20.1000 7.9600 10.0000 6.1700 13.9000 14.2000 12.3000 7.8800 10.0000 8.8800 1-Linoleoyl Glycerol 2.0800 0.4890 1.1000 7.2400 0.3000 0.7540 1.3700 1.0600 1.1200 0.9690 0.2080 2.0100 5.8500 1.5500 1.4800 1.3350 3.7000 8.3100 0.7130 0.4790 7.2900 0.0802 2.6600 9.4500 0.6000 36.2000 1.2100 2.6800 0.8370 1.6600 0.4850 0.2160 2.7500 5.3500 7.3500 0.1670 3.4000 2.4600 0.1910 1.3900 2.9600 4.9100 15.1000 1.3000 10.1000 7.1200 0.5250 5.1000 5.9300 1.7200 0.5040 1.8200 21.8000 0.9110 14.1000 4.5800 4.9200 0.2630 2.0900 1.6300 2.4500 1.5700 1.0800 0.5850 9.8000 1.5600 31.3000 3.5000 4.0000 1.3200 4.3200 1.3000 2.8900 1.3200 1.7900 0.8330 3.3100 8.4250 0.8800 2.2200 1.4300 1.0500 0.8040 2.6600 3.5700 1.6100 1.2600 1.3400 2.9900 1.4400 1.5100 0.7230 2.3700 3.6900 1.1900 4.8100 1.4100 8.9200 0.6750 1.8100 0.8970 1-Oleoyl Glycerol 25.0000 14.6000 31.4000 191.0000 91.7000 19.4000 19.2000 20.8000 60.0000 19.2000 17.9000 17.9000 93.9000 110.0000 173.5000 28.2000 20.8000 18.5000 82.8000 476.0000 35.7000 10.0000 149.0000 98.3000 72.2000 151.0000 114.0000 935.0000 18.8000 15.3000 20.5000 22.5000 47.6000 42.6000 111.0000 115.0000 85.2000 101.0000 105.0000 35.3000 40.3000 29.8000 18.1000 13.3000 119.0000 53.7000 492.0000 10.2000 74.1000 114.0000 104.0000 51.5000 70.0000 67.0000 34.5000 25.9000 40.1000 285.0000 49.7000 189.0000 39.3000 105.0000 32.4000 59.7000 24.5000 12.5000 33.8000 22.0000 24.0000 119.0000 13.3000 198.0000 90.9000 126.0000 45.2000 109.0000 30.4000 26.2000 34.9000 45.2000 35.2000 46.2000 62.3000 151.0000 42.1000 74.3000 81.1000 65.2000 32.8000 37.2000 56.4000 100.0000 75.6000 30.6000 69.5000 79.8000 119.0000 20.0000 47.1000 51.8000 72.2000 54.7000 149.0000 24.6000 206.0000 56.3000 238.0000 21.2000 2-Arachidonoyl Glycerol 16.5000 13.8000 16.0000 33.0000 15.4000 44.2000 28.7000 7.5000 37.2000 24.9000 20.7000 10.6000 52.0000 22.5000 15.2000 23.0000 21.4000 10.3750 27.9000 28.5000 21.4000 39.7000 40.2000 49.6000 12.5000 32.1000 10.4000 69.3000 11.6000 13.5000 7.7200 6.5100 9.5400 12.5000 9.5500 10.5000 6.6700 7.1500 9.2800 10.1000 41.7000 4.7500 2.1200 3.6000 3.6600 6.0700 8.9500 0.9480 6.0200 9.4500 15.4000 18.6000 11.0000 4.7800 3.9800 4.5100 5.3900 9.5700 2.1600 15.1000 5.7400 9.3200 5.0400 8.1500 26.5000 4.1800 2.3200 3.2800 4.6600 10.6000 2.2900 10.6000 5.7000 7.2800 11.6000 10.1000 11.9000 5.4500 3.5300 3.7500 5.8600 3.7500 2.1200 6.0700 44.1000 128.0000 20.6000 17.1000 80.0000 13.2000 33.0000 7.7400 38.6000 42.4000 39.6000 92.8000 11.8000 164.0000 134.0000 18.8000 28.7000 15.4000 35.9000 56.4000 21.9000 9.5900 17.4000 13.5000 2-Linoleoyl Glycerol 9.9000 9.2600 5.8100 36.3000 11.9000 10.2000 15.2000 6.9600 26.9000 7.1200 7.9900 7.6200 6.0800 19.4000 9.0850 9.2000 13.0000 6.8900 39.4000 44.9000 15.3000 10.8000 35.8000 11.7000 11.1000 39.0000 14.4000 228.0000 10.0000 16.9000 10.5000 10.6000 22.0000 18.1000 15.7000 28.5000 12.4000 21.1000 21.2000 8.6700 19.4000 7.4500 2.7600 5.9800 6.6800 15.6000 20.9000 1.0400 13.6000 29.5000 8.9600 7.5150 22.7000 8.4100 6.6800 7.0150 10.5000 24.8000 2.8500 20.3000 10.3000 23.9000 10.7000 6.6200 11.4000 9.1700 2.0600 5.1800 8.8100 41.6000 1.4100 29.6000 11.9000 22.0000 7.7500 6.9400 10.5000 8.0600 2.8300 4.4900 10.1000 9.4100 4.2900 14.2000 8.1700 21.3000 5.3900 0.2660 10.3000 3.4000 13.7000 9.7100 3.5000 7.3300 4.1900 9.2600 4.3400 8.2600 11.5000 16.3000 10.7000 8.2100 2.5900 9.1700 63.2000 1.8100 46.5000 7.9800 2-Oleoyl Glycerol 41.7000 33.6000 32.4000 129.0000 67.5000 56.2000 77.0000 25.5000 85.4000 39.1000 34.5000 26.6000 54.6000 78.5000 59.8000 47.9000 51.9000 34.4500 110.0000 277.0000 74.8000 42.5000 150.0000 107.0000 76.1000 138.0000 88.4000 1340.0000 33.8000 44.8000 57.6000 44.9000 101.0000 109.0000 109.0000 238.0000 87.2000 89.9000 87.0000 38.7000 62.2000 22.5000 11.9000 20.9000 29.8000 75.7000 175.0000 10.0000 71.5000 104.0000 41.2000 54.1000 82.8000 20.1000 32.9000 41.3000 73.6000 146.0000 22.2000 159.0000 38.1000 109.0000 30.8000 31.5000 34.4000 20.0000 11.7000 20.3000 45.3000 250.0000 18.6000 165.0000 40.8000 108.0000 46.6000 49.6000 42.3000 27.5000 12.8000 19.1000 52.9000 66.5000 36.6000 99.5000 74.9000 139.0000 28.1000 30.3000 61.7000 24.3000 121.0000 64.4000 98.6000 70.4000 49.7000 118.0000 64.3000 47.9000 75.0000 92.3000 116.0000 49.4000 73.4000 61.8000 502.0000 17.2000 417.0000 41.3000 a-Linolenoyl Ethanolamide 0.0478 0.0582 0.0601 0.0899 0.0668 0.0543 0.0554 0.0420 0.0601 0.0580 0.0912 0.0576 0.0309 0.0528 0.0379 0.0219 0.0345 0.0208 0.0778 0.0270 0.0225 0.0472 0.0497 0.0420 0.1230 0.1210 0.0951 0.0497 0.1110 0.0668 0.0629 0.0383 0.0564 0.0821 0.0637 0.0410 0.0453 0.0376 0.0572 0.0367 0.0687 0.0414 0.0401 0.0459 0.0320 0.0377 0.0421 0.0265 0.0299 0.0269 0.0511 0.0284 0.0514 0.0522 0.0425 0.0383 0.0470 0.0513 0.0260 0.0357 0.0593 0.0321 0.0396 0.0206 0.0599 0.0479 0.0509 0.0390 0.0333 0.0432 0.0608 0.0301 0.0338 0.0343 0.0312 0.0464 0.0501 0.0570 0.0428 0.0383 0.0437 0.0229 0.0287 0.0253 0.0583 0.0388 0.0851 0.0606 0.0645 0.0509 0.0484 0.0571 0.0354 0.0362 0.0923 0.0439 0.0961 0.0503 0.0312 0.0284 0.0363 0.0386 0.0228 0.0257 0.0349 0.0595 0.0349 0.0531 Arachidonoyl Ethanolamide 1.6600 1.8000 1.4700 2.1400 1.9100 1.4200 0.4510 1.6900 1.7800 1.5400 2.2600 1.9400 1.2100 1.7400 1.4200 0.9360 0.5350 0.9980 1.9500 1.2700 0.4670 0.4090 0.8940 0.6190 1.8400 2.1400 2.0400 1.8000 2.0000 1.6300 1.9000 1.9500 1.4000 2.0300 1.1500 1.6400 2.0500 1.2800 1.7200 1.0600 1.6400 0.9700 1.0700 2.3000 1.6800 1.3100 1.4100 0.7640 1.1200 1.1000 1.1700 1.2000 1.3300 1.5900 1.0400 1.9600 1.3700 1.6800 1.0100 1.9400 1.7200 1.4800 1.6900 0.7830 1.2700 1.2400 1.2900 2.0900 1.3200 1.3700 1.0100 1.1200 1.2500 1.1600 0.9480 1.1500 1.1900 1.4400 1.2400 1.9300 1.2500 1.2000 1.1100 1.4400 1.0200 0.3830 1.5300 1.4900 0.7260 1.1700 0.9670 1.4900 1.1200 0.7840 1.4200 1.0000 1.7700 0.8040 0.5740 0.9800 0.7210 1.1300 1.0900 0.6850 1.6500 2.7400 1.7400 1.3000 Dihomo-g-Linolenoyl Ethanolamide 0.2920 0.3150 0.1400 0.2950 0.2020 0.2530 0.0929 0.2650 0.2990 0.2820 0.6440 0.4150 0.2290 0.3030 0.2325 0.2890 0.1840 0.1114 0.4650 0.2600 0.1010 0.1430 0.2690 0.2140 0.4430 0.1790 0.3920 0.1890 0.4730 0.1870 0.5190 0.2740 0.3330 0.1840 0.3140 0.1800 0.4370 0.1530 0.2350 0.1200 0.3530 0.1160 0.1430 0.2160 0.2850 0.1190 0.2160 0.0973 0.1370 0.1590 0.1680 0.1160 0.1920 0.2500 0.1280 0.2660 0.1570 0.1240 0.1580 0.3730 0.2140 0.1680 0.2460 0.0542 0.2030 0.1080 0.2000 0.2410 0.2370 0.1490 0.4260 0.1020 0.2000 0.1330 0.1590 0.0959 0.2810 0.1940 0.2550 0.3750 0.1830 0.1300 0.1320 0.1935 0.3400 0.2380 0.4950 0.1820 0.2390 0.1720 0.1810 0.4620 0.2680 0.1880 0.2120 0.1910 0.2530 0.2110 0.1330 0.1860 0.2870 0.2100 0.1890 0.1800 0.3140 0.4930 0.2180 0.3230 Docosahexaenoyl Ethanolamide 3.0000 3.0100 2.5700 3.8300 3.0600 2.9400 3.0500 3.1400 3.0100 3.1500 3.9400 3.2000 2.3800 3.5000 2.4300 2.1500 3.7900 2.5000 3.7900 1.8800 3.2700 5.0800 4.8200 3.5400 3.7200 4.1100 2.4100 3.2100 3.8400 3.7900 3.0700 3.4100 2.4500 2.6400 1.2400 1.9400 2.1600 2.1100 2.5000 1.5800 2.5100 2.5700 1.9700 3.5000 2.4000 2.0200 1.9400 1.2200 2.0500 2.0200 2.1800 2.1000 2.4700 3.4400 1.5000 2.6750 2.8600 3.0800 1.9200 2.6400 2.8600 2.5200 2.1600 1.5200 2.2300 3.1300 1.8500 3.1500 2.6200 2.1500 2.0000 1.7000 1.8800 1.9000 1.7400 2.1000 2.1600 3.2300 1.8700 3.1300 2.6700 2.0300 1.7900 1.7050 4.3100 2.7700 5.4000 4.4400 4.1100 6.0500 4.7200 6.0000 3.7800 3.5500 8.0600 5.2000 7.8100 2.7200 2.8500 6.4300 5.9300 5.2700 3.7600 4.0400 3.1100 5.0900 3.0100 2.4100 Docosatetraenoyl Ethanolamide 0.6480 0.8580 0.6900 0.5150 0.4240 0.4520 0.1160 0.7480 0.0822 0.2030 1.3900 0.6860 0.4660 0.3770 0.2278 0.5460 0.0876 0.3840 0.7500 0.4220 0.1400 0.0400 0.2040 0.7150 0.7470 0.4640 1.0500 0.4580 1.6100 0.7810 1.4000 0.6290 1.3100 1.2000 0.9100 1.1700 1.5600 0.3260 0.5330 0.0898 0.6400 0.4730 0.6120 0.5310 0.8640 0.3870 0.6540 0.4670 0.4750 0.3120 0.3670 0.0877 0.4470 0.9910 0.3450 0.6710 0.5720 0.4080 0.4230 1.2700 0.3520 0.2150 0.5720 0.1890 0.4870 0.3050 0.5760 0.5880 0.8880 0.4120 0.4230 0.2770 0.4610 0.2180 0.1740 0.1410 0.9350 0.7730 0.7210 0.7380 0.7940 0.4130 0.4320 0.7030 0.9740 0.0974 1.3100 0.8770 0.4820 0.8930 0.5630 1.8500 0.9700 0.1820 0.9580 0.5950 1.0700 0.3410 0.0585 0.7610 0.6210 0.8300 1.0300 0.1200 0.9440 1.4400 1.1300 1.3500 Linoleoyl Ethanolamide 0.7600 0.8320 0.5570 1.1800 1.0000 0.7460 0.5630 0.7480 1.1300 0.7990 1.0900 1.0100 0.5840 0.9220 0.7950 0.4670 0.6640 0.4535 1.1900 0.5510 0.4120 0.7060 0.9260 0.8180 0.9620 1.7700 1.3100 1.2700 0.7930 1.1900 1.0800 0.9900 0.9150 1.0200 0.9890 0.7070 1.0200 0.8760 1.3000 1.1000 0.7960 0.6940 0.7400 1.1900 1.0800 0.5780 0.6970 0.4340 0.7770 0.9480 1.5000 0.6490 1.1200 1.0800 0.6350 0.8590 0.8230 1.0400 0.5390 0.8500 0.8960 1.0300 0.9130 0.7690 0.8510 0.8650 0.6530 1.0400 0.7880 0.7320 0.6370 0.5520 1.0100 0.7530 0.7840 1.1600 0.7230 0.9280 0.7390 1.0300 0.7760 0.6150 0.6300 0.5655 0.9530 0.8220 1.4100 1.4900 0.8630 0.9810 1.0500 1.8100 1.1800 0.9660 1.3300 1.2500 1.7400 1.0900 0.9210 0.9510 0.9580 1.0300 1.4400 0.8630 0.9900 1.1200 1.2900 0.5660 Oleoyl Ethanolamide 28.1000 28.5000 21.7000 35.9000 30.2000 27.8000 13.0000 26.8000 26.2000 19.9000 40.4000 28.6000 29.7000 31.0000 24.6500 25.1000 15.2000 17.5000 37.1000 27.3000 10.2000 16.5000 19.1000 18.4000 16.9000 34.3000 42.8000 35.3000 34.5000 26.1000 53.5000 31.9000 31.5000 37.8000 28.8000 34.3000 52.3000 18.7000 32.1000 20.8000 27.6000 15.8000 21.0000 33.0000 24.4000 11.2000 19.1000 12.9000 19.8000 24.0000 29.9000 18.2500 23.3000 29.0000 26.0000 40.1000 20.7000 14.4000 12.4000 31.9000 14.6000 21.2000 24.7000 17.0000 22.3000 14.6000 26.6000 35.3000 21.0000 17.9000 12.9000 9.9400 26.5000 16.8000 22.1000 22.5000 28.0000 27.8000 31.9000 44.7000 23.7000 16.4000 12.8000 20.9500 25.4000 26.2000 26.7000 30.6000 18.8000 23.0000 25.7000 36.4000 34.3000 16.5000 29.4000 22.6000 34.3000 29.1000 13.0000 16.8000 26.3000 22.0000 34.8000 9.5900 31.5000 43.8000 43.5000 35.0000 Palmitoyl Ethanolamide 13.3000 14.6000 13.1000 18.1000 15.0000 18.5000 9.0000 13.3000 20.5000 12.0000 18.4000 15.1000 15.8000 13.3000 15.4000 9.5200 15.0000 11.9500 22.1000 12.3000 11.0000 13.4000 14.3000 10.6000 15.9000 65.0000 22.1000 21.0000 15.6000 17.9000 16.0000 22.3000 4.8100 8.9600 6.6500 6.0100 11.1000 13.7000 36.9000 10.2000 14.8000 12.4000 12.6000 21.8000 8.9300 4.7900 7.2000 4.5400 15.1000 17.9000 51.3000 14.8500 14.7000 12.6000 17.7000 19.1000 8.2000 5.6700 5.8700 12.4000 23.4000 11.5000 35.6000 30.5000 12.9000 13.3000 9.9000 20.8000 6.0700 5.1900 4.5600 7.4200 32.7000 10.3000 10.4000 48.0000 15.2000 15.5000 10.8000 26.4000 7.5500 4.5500 6.4600 6.5050 20.5000 15.7000 17.1000 14.2000 12.3000 14.4000 14.0000 14.3000 15.6000 15.2000 19.4000 14.6000 16.6000 18.3000 9.5300 15.6000 33.6000 14.6000 16.2000 10.2000 12.9000 13.3000 15.4000 12.5000 PGF2a Ethanolamide 0.1220 0.0771 0.0884 0.0521 0.0785 0.0713 0.0982 0.0270 0.0623 0.0721 0.0730 0.0124 0.0870 0.0851 0.1040 0.0303 0.0866 0.0278 0.0440 0.0848 0.0443 0.0130 0.2540 0.1300 0.0916 0.1300 0.2260 0.1590 0.1580 0.1960 0.0592 0.0277 0.0578 0.1200 0.1610 0.1260 0.1830 0.1360 0.2060 0.1850 0.1570 0.1660 0.0952 0.1090 0.0940 0.0413 0.1040 0.1540 0.1900 0.1084 0.1760 0.1410 0.1570 0.1735 0.0722 0.0466 0.1370 0.0098 0.0107 0.0775 0.1620 0.1620 0.1360 0.1730 0.1720 0.2020 0.0760 0.0403 0.0608 0.0139 0.0574 0.0882 0.1300 0.1420 0.1990 0.1690 0.1480 0.1570 0.0524 0.0366 0.0427 0.0659 0.0206 0.1140 0.0651 0.0756 0.0167 0.0814 0.0586 0.0349 0.0995 0.0844 0.0026 0.0450 0.1560 0.0894 0.1110 0.0673 0.0820 0.0766 0.0833 0.0804 0.1330 Stearoyl Ethanolamide 14.5000 27.2000 17.9000 17.1000 13.0000 15.7000 11.6000 20.0000 19.5000 7.9700 42.1000 18.9000 17.5000 18.3000 18.4500 12.8000 22.9000 15.5000 43.0000 19.2000 18.7000 22.4000 18.7000 59.5000 18.5000 105.0000 45.9000 34.2000 23.0000 18.6000 47.0000 30.4000 73.0000 36.6000 49.0000 55.5000 61.9000 18.7000 84.8000 8.2300 14.3000 13.2000 21.5000 23.7000 48.4000 12.1000 28.8000 23.1000 41.0000 29.1000 78.1000 16.6500 18.4000 16.7000 31.6000 35.9000 32.8000 21.8000 20.5000 21.0000 22.6000 13.3000 59.2000 43.6000 12.3000 13.1000 16.4000 26.1000 51.7000 19.6000 15.1000 17.2000 71.8000 15.4000 11.3000 59.6000 25.4000 21.4000 22.3000 50.4000 40.9000 22.0000 17.4000 30.6000 34.7000 42.5000 38.3000 30.2000 16.5000 24.3000 22.7000 56.1000 30.1000 15.0000 30.9000 31.6000 31.5000 27.1000 18.6000 27.7000 85.3000 43.4000 50.7000 9.9000 24.2000 33.5000 45.7000 29.8000 MS_METABOLITE_DATA_END #METABOLITES METABOLITES_START metabolite_name moverz_quant ri ri_type pubchem_id inchi_key kegg_id other_id other_id_type 1-Arachidonoyl Glycerol 114672 HMDB11538 UCDavis_Newman_ID 1-Linoleoyl Glycerol 117319 HMDB11578 UCDavis_Newman_ID 1-Oleoyl Glycerol HMDB11567 UCDavis_Newman_ID 2-Arachidonoyl Glycerol 5282280 HMDB04666 UCDavis_Newman_ID 2-Linoleoyl Glycerol 549043 HMDB11537 UCDavis_Newman_ID 2-Oleoyl Glycerol 543397 HMDB11568 UCDavis_Newman_ID a-Linolenoyl Ethanolamide HMDB13624 UCDavis_Newman_ID Arachidonoyl Ethanolamide 5281969 HMDB04080 UCDavis_Newman_ID Dihomo-g-Linolenoyl Ethanolamide HMDB13625 UCDavis_Newman_ID Docosahexaenoyl Ethanolamide 5283451 HMDB13627 UCDavis_Newman_ID Docosatetraenoyl Ethanolamide 53394363 HMDB13626 UCDavis_Newman_ID Linoleoyl Ethanolamide HMDB12252 UCDavis_Newman_ID Oleoyl Ethanolamide 5283454 HMDB02088 UCDavis_Newman_ID Palmitoyl Ethanolamide 52922083 HMDB02100 UCDavis_Newman_ID PGF2a Ethanolamide 53481911 HMDB13628 UCDavis_Newman_ID Stearoyl Ethanolamide 27902 HMDB13078 UCDavis_Newman_ID METABOLITES_END #END