#METABOLOMICS WORKBENCH michaelsa93_20160513_091042_mwtab.txt DATATRACK_ID:628 STUDY_ID:ST000399 ANALYSIS_ID:AN000636 PROJECT_ID:PR000312 VERSION 1 CREATED_ON May 17, 2016, 2:24 pm #PROJECT PR:PROJECT_TITLE E.coli effects on growth and substrate uptake of green algae PR:PROJECT_SUMMARY The purpose of this project was to quantify the exchange of thiamine between PR:PROJECT_SUMMARY bacteria and algae. We previously observed that the model bacteria, Escherichia PR:PROJECT_SUMMARY coli, enhanced the growth and substrate uptake of the green algae, PR:PROJECT_SUMMARY Auxenochlorella protothecoides. We hypothesized that this growth enhancement was PR:PROJECT_SUMMARY due to the secretion of thiamine derivatives or degradation products by E. coli PR:PROJECT_SUMMARY followed by uptake of these compounds by A. protothecoides. Targeted and PR:PROJECT_SUMMARY untargeted LCMS revealed the presence of thiamine dervatives in E. coli cell PR:PROJECT_SUMMARY extracts. These LCMS methods were also used to quantify thiamine derivatives and PR:PROJECT_SUMMARY two degradation products, HMP and THZ, present in E. coli medium after cell PR:PROJECT_SUMMARY removal. The LCMS results along with culture studies were employed to show that PR:PROJECT_SUMMARY thiamine derivatives and degradation products were the primary mechanism of PR:PROJECT_SUMMARY symbiosis between E. coli and A. protothecoides. PR:INSTITUTE University of California, Davis PR:DEPARTMENT Genome and Biomedical Sciences Facility PR:LABORATORY WCMC Metabolomics Core PR:LAST_NAME Fiehn PR:FIRST_NAME Oliver PR:ADDRESS 1315 Genome and Biomedical Sciences Facility, 451 Health Sciences Drive, Davis, PR:ADDRESS CA 95616 PR:EMAIL ofiehn@ucdavis.edu PR:PHONE (530) 754-8258 PR:FUNDING_SOURCE NIH U24DK097154 #STUDY ST:STUDY_TITLE E.coli effects on growth and substrate uptake of green algae (part I - HILIC) ST:STUDY_SUMMARY The purpose of this project was to quantify the exchange of thiamine between ST:STUDY_SUMMARY bacteria and algae. We previously observed that the model bacteria, Escherichia ST:STUDY_SUMMARY coli, enhanced the growth and substrate uptake of the green algae, ST:STUDY_SUMMARY Auxenochlorella protothecoides. We hypothesized that this growth enhancement was ST:STUDY_SUMMARY due to the secretion of thiamine derivatives or degradation products by E. coli ST:STUDY_SUMMARY followed by uptake of these compounds by A. protothecoides. Targeted and ST:STUDY_SUMMARY untargeted LCMS revealed the presence of thiamine dervatives in E. coli cell ST:STUDY_SUMMARY extracts. These LCMS methods were also used to quantify thiamine derivatives and ST:STUDY_SUMMARY two degradation products, HMP and THZ, present in E. coli medium after cell ST:STUDY_SUMMARY removal. The LCMS results along with culture studies were employed to show that ST:STUDY_SUMMARY thiamine derivatives and degradation products were the primary mechanism of ST:STUDY_SUMMARY symbiosis between E. coli and A. protothecoides. ST:INSTITUTE University of California, Davis ST:DEPARTMENT Genome and Biomedical Sciences Facility ST:LABORATORY WCMC Metabolomics Core ST:LAST_NAME Fiehn ST:FIRST_NAME Oliver ST:ADDRESS 1315 Genome and Biomedical Sciences Facility, 451 Health Sciences Drive, Davis, ST:ADDRESS CA 95616 ST:EMAIL ofiehn@ucdavis.edu ST:PHONE (530) 754-8258 #SUBJECT SU:SUBJECT_TYPE Cells SU:SUBJECT_SPECIES Escherichia coli SU:TAXONOMY_ID 562 #SUBJECT_SAMPLE_FACTORS: SUBJECT(optional)[tab]SAMPLE[tab]FACTORS(NAME:VALUE pairs separated by |)[tab]Additional sample data SUBJECT_SAMPLE_FACTORS BH28 BH28_HILIC.d Type of media samples:Base Degraded Thiamine SUBJECT_SAMPLE_FACTORS BH29 BH29_HILIC.d Type of media samples:Fractionated using RP column SUBJECT_SAMPLE_FACTORS BH30 BH30_HILIC.d Type of media samples:Fractionated using RP column SUBJECT_SAMPLE_FACTORS BH31 BH31_HILIC.d Type of media samples:Fractionated using RP column SUBJECT_SAMPLE_FACTORS BH32 BH32_HILIC.d Type of media samples:Fractionated using RP column SUBJECT_SAMPLE_FACTORS BH33 BH33_HILIC.d Type of media samples:Fractionated using RP column SUBJECT_SAMPLE_FACTORS BH34 BH34_HILIC.d Type of media samples:Fractionated using RP column SUBJECT_SAMPLE_FACTORS BH35 BH35_HILIC.d Type of media samples:Methanol Extracted SUBJECT_SAMPLE_FACTORS BH36 BH36_HILIC.d Type of media samples:Methanol Extracted #COLLECTION CO:COLLECTION_SUMMARY Cultures were harvested after 5 days of growth, washed with dH2O, and freeze CO:COLLECTION_SUMMARY dried 5 ml of trichloroacetic acid was added to entire freeze dried cell pellet CO:COLLECTION_SUMMARY in 15 ml tube, vortexed, and incubated on shaker at 150 rpm for 3 hours TCA was CO:COLLECTION_SUMMARY extracted twice w/ 5ml diethyl ether, then sample was washed with 5 ml CO:COLLECTION_SUMMARY chloroform, and aqueous phase was recovered Freeze-dried aqueous phase, CO:COLLECTION_SUMMARY resuspended in 1 ml MeOH and incubated on shaker for 1 hour at 150 rpm, CO:COLLECTION_SUMMARY centrifuged Supernatant was trasnferred to 2 ml tube, sample washed with CO:COLLECTION_SUMMARY additional 0.5 ml MeOH and added to 2 ml tube Freeze dried. Note that a method CO:COLLECTION_SUMMARY blank and 2 recovery standards containing thiamine were included in this CO:COLLECTION_SUMMARY processing CO:COLLECTION_PROTOCOL_FILENAME Thiamine_BH_IG032715QTrap.xlsx CO:SAMPLE_TYPE Cell #TREATMENT TR:TREATMENT_SUMMARY BH28 was base degraded thiamine. It did not come from an organism. It was TR:TREATMENT_SUMMARY suspended thiamine in strong base for an extended period of time. This was done TR:TREATMENT_SUMMARY to see what types of degraded products would form. BH29-34 were E. coli medium TR:TREATMENT_SUMMARY samples that were fractionated using a reverse phase column. BH35-36 were media TR:TREATMENT_SUMMARY samples after E. coli growth where methanol was used for extraction. #SAMPLEPREP SP:SAMPLEPREP_SUMMARY 1. Add 0.5mL of extraction solvent to tube, gently pipet to remove all cells, SP:SAMPLEPREP_SUMMARY transfer cells to 2mL eppendorf tube. Repeat for a total of 1mL extraction SP:SAMPLEPREP_SUMMARY solvent + cells in 2mL eppendorf tube. 2. Add 2 small stainless steel grinding SP:SAMPLEPREP_SUMMARY beads to eppendorf tube 3. Use the GenoGrinder to grind for 3 minutes at 1,250 SP:SAMPLEPREP_SUMMARY rpm. 4. Centrifuge at 14,000xg for 5 minutes. 5. Transfer supernatant to a fresh SP:SAMPLEPREP_SUMMARY 2mL eppendorf tube. 6. Add 1mL of extraction solvent to tube containing cell SP:SAMPLEPREP_SUMMARY pellet + beads, and repeat steps 3 and 4. 7. Collect supernatant, and combine SP:SAMPLEPREP_SUMMARY with supernatant collected in step 5. Total volume of extracted sample will be SP:SAMPLEPREP_SUMMARY approximately 2mL. 8. Dry down 50uL of extracted sample in 1.5mL eppendorf tube SP:SAMPLEPREP_SUMMARY for GC-TOF analysis. 9. Store backups in -20 or -80C. SP:SAMPLEPREP_PROTOCOL_FILENAME SOP_Extraction_of_Yeast_Cells.pdf #CHROMATOGRAPHY CH:CHROMATOGRAPHY_TYPE HILIC CH:INSTRUMENT_NAME Agilent 6530 CH:COLUMN_NAME Waters Acquity BEH Amide (150 x 2.1mm, 1.7um) CH:COLUMN_NAME Waters Acquity CH:FLOW_GRADIENT 100% B to 30% B CH:FLOW_RATE 0.4 mL/min CH:COLUMN_TEMPERATURE 45 C CH:METHODS_FILENAME Data_Dictionary_Fiehn_laboratory_HILIC_QTOF_MS.pdf CH:SOLVENT_A Ultrapure water with 10 mM ammonium formiate + 0.125% formic acid, pH 3 CH:SOLVENT_B Ultrapure water with 10 mM ammonium formiate + 0.125% formic acid, pH 3 CH:COLUMN_PRESSURE 200-700 bar CH:INJECTION_TEMPERATURE 4 C CH:INTERNAL_STANDARD See data dictionary CH:RETENTION_TIME See data dictionary CH:SAMPLE_INJECTION 3uL CH:ANALYTICAL_TIME 14 min CH:CAPILLARY_VOLTAGE 4500 V CH:TIME_PROGRAM 16.75 min CH:WEAK_WASH_SOLVENT_NAME 1:1 ACN:H2O CH:STRONG_WASH_SOLVENT_NAME 1:1 ACN:H2O CH:TARGET_SAMPLE_TEMPERATURE Autosampler temp 4 C CH:RANDOMIZATION_ORDER Excel generated #ANALYSIS AN:ANALYSIS_TYPE MS AN:LABORATORY_NAME WCMC Metabolomics Core AN:SOFTWARE_VERSION ChromaTOF AN:DATA_FORMAT .d #MS MS:MS_COMMENTS - MS:INSTRUMENT_NAME Agilent 6530 QTOF MS:INSTRUMENT_TYPE QTOF MS:MS_TYPE ESI MS:ION_MODE POSITIVE MS:CAPILLARY_VOLTAGE 3500 V MS:COLLISION_GAS Nitrogen MS:DRY_GAS_FLOW 8 L/min MS:DRY_GAS_TEMP 325 C MS:FRAGMENT_VOLTAGE 120 V MS:FRAGMENTATION_METHOD Auto MS/MS MS:ION_SOURCE_TEMPERATURE 325 MS:ION_SPRAY_VOLTAGE 1000 MS:IONIZATION Pos MS:PRECURSOR_TYPE Intact Molecule MS:REAGENT_GAS Nitrogen MS:SOURCE_TEMPERATURE 325 C MS:DATAFORMAT .d MS:DESOLVATION_GAS_FLOW 11 L/min MS:DESOLVATION_TEMPERATURE 350 C MS:NEBULIZER 35 psig MS:OCTPOLE_VOLTAGE 750 V MS:RESOLUTION_SETTING extended dynamic range MS:SCAN_RANGE_MOVERZ 60-1700 Da MS:SCANNING_CYCLE 2 Hz MS:SCANNING_RANGE 60-1700 Da MS:SKIMMER_VOLTAGE 1850 V #MS_METABOLITE_DATA MS_METABOLITE_DATA:UNITS counts MS_METABOLITE_DATA_START Samples BH28_HILIC.d BH29_HILIC.d BH30_HILIC.d BH31_HILIC.d BH32_HILIC.d BH33_HILIC.d BH34_HILIC.d BH35_HILIC.d BH36_HILIC.d Factors Type of media samples:Base Degraded Thiamine Type of media samples:Fractionated using RP column Type of media samples:Fractionated using RP column Type of media samples:Fractionated using RP column Type of media samples:Fractionated using RP column Type of media samples:Fractionated using RP column Type of media samples:Fractionated using RP column Type of media samples:Methanol Extracted Type of media samples:Methanol Extracted 1.26_163.08 2819 5986 7162 9617 5865 8525 7470 6491 170842 1.29_146.06 4060 88528 2294 22099 43467 1587063 1.26_167.03 30944 19388 9.62_355.11 11656 12409 7.14_132.1 2691 233015 423819 10475 6914 6401 15199 68382 6.09_154.1 10631 12307 6153 1.84_206.14 2643 6895 3307 5312 5253 2560 2442 8.85_148.06 50950 546887 14361 2427 639454 28522 8.4_147.07 7436 10432 6.82_209.09 11234 2023 13299 4923 1.42_170.08 18017 21120 8.15_112.04 10204 8893 12225 7.63_118.09 2542 148037 1049158 27235 26830 26451 26603 420719 179850 7.47_139.1 9401839 1829113 767391 532429 371402 267042 198547 125267 183385 8.06_139.1 9091765 432686 404287 266578 283387 177715 132752 49703 49724 8.05_265.11 1847090 89210 156972 86903 71936 54269 47068 10154 11868 7.3_265.11 4962957 350624 255377 130470 131580 110641 80327 33152 93664 1.42_144.06 92455 5403 2032 2263 5505 4798 1.05_688.2 68002 81336 26440 145021 1.05_750.52 11510 22236 32166 2872 27302 40141 13784 1.05_684.2 609640 785109 229293 18280 1311877 1.05_1073.31 44407 4723 5776 79506 2867 4391 24957 1.05_1074.31 44387 4292 5903 76742 2922 3872 25340 1.06_998.29 4367 55488 5615 5985 86456 4882 4294 34410 1.06_1148.32 29462 3598 5721 58736 2024 4028 16796 1.06_792.61 15512 9226 18948 17367 13455 1.06_1000.29 3952 48577 5269 5775 75123 4761 3845 31287 1.06_1194.82 8434 5789 6049 14009 1.06_1002.28 2804 16831 2276 25678 12830 1.06_610.18 457092 231215 123214 16276 552704 1.06_924.27 25569 54101 6668 7677 81248 10930 4668 46045 1.06_999.29 4128 49670 5002 6339 82131 4639 4075 32754 1.06_925.27 21452 47644 6808 7392 69288 8829 4304 37735 1.06_536.17 255556 197140 116647 30997 321959 1.06_722.52 28995 63213 41574 2963 76057 70956 58400 1.06_721.51 52667 131796 84728 5576 155137 148055 2361 119191 1.06_850.25 79821 44310 8304 7817 67031 23445 4873 53496 1.07_776.23 173541 37839 9769 7924 57291 38187 5069 64818 1.07_702.21 237381 35174 12615 8524 51505 53667 5212 73064 1.07_531.41 7497 3419 4139 2161 6875 20412 18467 1.08_665.45 144353 386943 79331 3808 228941 176289 356078 1.08_419.31 537227 2786582 52072 83545 386336 36166 2261 134762 1.08_628.19 112804 25657 18894 7344 41876 67046 4566 67919 1.08_686.45 14560 45057 15181 6589 43383 13578 19719 1.08_637.31 14038 9047 6983 4386 13317 34308 18240 1.08_654.33 33655 20409 15610 10209 29756 77414 39076 1.08_680.48 76056 96297 21194 3537 62722 48592 98175 1.09_433.33 31751 138811 10618 5328 23382 7233 11523 1.09_149.02 106311 51082 8195 5951 9507 7584 2512 78924 68904 1.1_548.42 75053 32976 24378 11253 23066 16516 18971 1.1_607.39 9216 12297 5614 2420 8316 7928 12366 1.1_519.4 4730 3956 2105 2946 13818 1.11_504.39 47300 18753 19130 12914 21896 12221 3471 1.11_447.28 5251 9526 56450 75194 60533 21025 14860 7742 1.11_323.15 10760 15780 3230 9595 19991 1.11_446.3 12683 18355 212311 275729 217044 36810 19660 16540 1.11_929.62 25184 30606 67880 45326 69519 1.11_562.39 17423 9875 30139 27697 90064 5463 5319 1.11_636.46 60822 28907 17720 4305 12625 10623 10063 1.12_329.19 6191 20396 32829 20646 22923 35433 18906 30913 1.12_592.43 77716 36120 25470 8413 25968 14956 3415 1.12_606.46 16346 13181 7132 2523 8785 6626 29014 1.12_457.28 6477 26467 13806 14636 26418 5471 10752 9065 1.12_460.36 14333 5816 7389 7714 12131 4373 2444 1.12_322.2 2343 103992 179251 141176 108291 139176 112333 50292 1.12_422.25 5305 20975 39964 20840 36842 45199 24391 18507 1.12_427.18 17700 12318 4774 3146 6110 5354 1.12_434.28 5352 45076 78937 33918 56792 92147 40100 44764 1.12_301.16 11663 217044 329802 332957 199804 362381 276278 72051 1.12_346.29 3478 6833 7491 5381 11711 4901 1.13_268.17 91559 62428 243557 91250 167752 116278 109792 106736 1.13_518.3 12411 35881 36844 19258 30614 57314 15915 32167 1.13_318.19 3605 187397 286065 293630 177663 322279 246399 65341 1.13_297.17 3442 11600 21422 14428 13632 23976 13421 7005 1.13_358.2 7662 14623 56031 36600 112273 28917 39732 13398 1.13_371.21 9674 14865 25088 12015 18441 30781 12937 15819 1.13_372.23 42474 3813 27173 36542 27627 6938 5394 3958 1.13_418.24 6644 190135 328486 141672 218409 455653 168747 120521 1.13_504.29 39778 23374 26896 17269 21818 37782 11496 19875 1.13_328.16 2011 2461 11062 6369 11670 3150 5684 6080 1.13_399.25 83858 133733 648365 499828 1646991 173977 204750 598994 1.13_334.21 20618 33283 29172 22619 31467 26949 13158 1.13_446.28 15244 18355 212311 275729 217044 36810 20982 16540 1.13_506.3 8185 78831 86682 45694 73388 110046 35418 83363 1.13_393.22 37888 7709 10114 6396 7280 11357 6191 1.13_593.34 9776 5430 6706 3458 5277 8677 2203 5994 1.13_592.34 23201 14609 18016 8388 12926 24466 6270 17307 1.13_421.24 13892 19873 15701 19882 11205 10685 12780 1.14_302.18 2974 36902 54050 54225 35105 59180 45265 15689 1.14_420.32 149705 805524 17390 11296 290117 221582 3704 43116 1.14_606.36 18012 13021 15663 7089 15329 21784 5083 24667 1.14_421.32 25311 132906 4481 4050 17545 53634 10881 1.14_359.2 2710 5287 16229 11113 27018 9987 11603 6211 1.14_492.28 3386 34356 38291 19049 28466 47792 17266 29358 1.14_701.41 17389 82240 6966 5631 6432 4950 3303 5749 1.14_411.2 2985 9794 26190 17055 11609 25694 25215 7768 1.14_297.08 71177 3287 2372 2774 4334 5395 8529 1.14_563.32 6656 89441 25745 160763 8796 1.14_306.18 10468 52672 72712 99471 50586 74765 77859 35789 1.14_357.19 71638 120321 62976 86210 146710 66904 59239 1.15_369.19 2348 34326 54800 25773 37535 81225 30723 22833 1.15_327.2 15030 5719 8435 5847 6715 10832 5704 6100 1.15_347.31 12513 3920 3054 3075 2463 4338 7495 1.15_390.24 4942 14859 147705 122247 134905 30696 59245 13616 1.15_245.15 4472 6604 5801 4859 6152 4782 5741 1.15_259.14 2061 4793 6305 5548 7337 5782 4323 6178 1.15_291.15 10296 13304 18797 15109 16326 23128 14160 14432 1.15_520.41 248497 93267 79367 23621 92285 69616 5551 1.15_385.22 3577 7061 11025 5227 9990 13281 5627 7507 1.15_450.37 40176 43890 18518 19409 21681 18428 9832 1.15_410.26 2664 28280 25762 13074 26780 25679 14504 11349 1.15_1000.78 13428 7071 12170 31526 1.15_315.18 6868 11673 8195 6659 11556 7731 5330 1.15_323.21 2435 23683 36533 31416 23071 29401 25041 13498 1.15_476.39 163873 55625 52064 27285 65310 44840 2277 1.16_556.32 4615 7939 31045 25986 47129 7020 1.16_386.25 5406 4881 11651 11274 34707 7060 4517 14588 1.16_448.35 50444 37845 20999 14642 31026 27534 4075 3969 1.16_376.21 4098 6406 4823 6961 5821 3750 4617 1.16_332.2 6587 10177 8487 7608 11519 7951 4436 1.16_227.13 3182 8444 9896 11990 8217 11663 9387 5915 1.16_490.36 25419 20881 14168 6102 21319 17651 8778 1.16_319.28 11373 12881 8918 7150 9362 13229 6325 17962 1.16_600.39 8279 11511 17660 19244 20273 10773 2130 10334 1.16_408.36 12544 8628 15496 6950 7061 11495 2028 27734 1.16_255.13 37640 50999 57890 33619 54941 47247 18579 1.16_350.32 16066 39567 19812 17516 17891 28296 13225 48905 1.16_436.26 2479 11399 10897 5235 4876 6779 3278 5017 1.17_405.3 11632 56502 8047 6013 9882 6644 6880 1.17_565.44 66004 28100 27472 6204 29556 20420 3396 1.17_452.39 11946 9466 15822 7896 8597 9633 42321 1.17_392.24 2911 17252 19428 17128 16066 25175 12337 12061 1.17_564.44 206984 85348 83265 19272 89523 61703 2896 1.17_423.2 3767 3068 14753 7840 16853 13803 1.17_308.15 2193 20350 29795 23158 26978 31841 22538 20356 1.17_441.3 8014 27330 6548 3309 8625 6962 2547 20296 1.17_327.26 9908 3287 3661 3929 7241 2485 12261 1.17_532.38 4056 21214 65881 64910 216686 10381 11085 1.17_541.36 11815 19848 9237 2946 12070 9960 9437 1.17_287.15 8352 23174 29533 32771 21855 30136 26782 9849 1.17_226.19 35927 28992 223882 52245 22979 242049 3266 101059 1.17_335.23 26513 7312 7545 6559 9512 7452 5865 12575 1.17_494.4 61181 70925 30136 22762 38662 31660 11403 1.18_450.27 2223 9174 14110 11564 12907 6371 4767 11888 1.18_462.33 11579 13285 7688 3935 11967 9930 2474 6320 1.18_439.3 4954 16921 15009 5586 18392 29032 6518 206876 1.18_351.26 11644 4608 4860 3758 5889 5355 2860 15072 1.18_363.3 21137 9122 8704 5572 5978 6953 3331 24839 1.18_369.29 15968 6989 6360 3387 5036 7790 2035 6833 1.18_586.34 10354 15866 23129 16761 50188 5691 7609 1.18_285.17 2090 21865 27625 20058 18473 20819 21446 17268 1.18_492.39 77980 75068 43943 23640 63803 55775 4960 5861 1.18_578.41 28120 23279 17840 4898 24851 17217 7010 1.18_758.49 9940 8220 12499 11129 53607 6393 7782 6009 1.18_636.32 6304 9060 4144 8632 10524 1.18_107.08 10236 6191 8760 10808 16611 5540 5551 5798 1.18_609.46 48898 22732 23979 5342 23690 16150 1.18_404.22 5677 112501 195167 672185 768683 249977 107586 206290 1.18_333.29 12766 62943 11529 61237 53544 103244 6973 39248 1.18_608.46 142518 63930 69059 12806 67637 47384 3344 1.18_652.48 73231 44295 69056 11082 46625 38873 9323 1.18_261.13 53205 4660 5628 5340 5173 4089 4798 11857 1.18_443.27 8865 7984 7551 3963 14877 7190 3095 6773 1.19_377.31 27781 128199 12005 36882 146676 226686 3486 53063 1.19_343.18 14953 74628 14590 17581 27817 39534 42605 1.19_334.3 6948 12567 8221 10995 11183 16203 3025 11101 1.19_395.35 8220 10026 11945 8193 7474 9481 2795 23406 1.19_653.49 28725 17439 25426 4378 17644 15485 4497 1.19_209.12 39097 5416 7130 7313 6494 7594 6745 4959 1.19_332.28 26553 294881 35590 296320 259849 497915 11680 140794 1.19_438.37 27231 25807 42109 24609 23718 28011 8235 58872 1.19_192.18 3861 31139 4972 29437 31618 55929 16976 1.19_149.13 2095 8097 2697 6957 8978 14364 5165 6088 1.19_926.53 5720 4593 7227 4821 35062 5996 4900 1.19_499.32 6864 15239 7097 3507 10947 7094 20606 1.19_580.43 64842 69751 50691 16509 82145 48019 2391 3486 1.19_660.4 9184 7524 24197 13427 28011 6006 8143 1.19_349.26 385085 3760 3337 3261 5437 3014 2032 7249 1.19_191.18 21690 223977 27697 202016 208993 379772 8602 105952 115308 1.19_656.49 9411 8326 10125 4596 9411 9856 21035 1.19_551.28 4528 2214 25164 14589 82332 13853 1.19_582.44 37148 44944 29811 13351 34963 25816 7208 1.19_135.11 4629 48761 6309 38820 48967 83838 2834 25207 25468 1.19_376.3 14700 564148 15893 160075 660033 986576 5315 218979 1.19_424.36 16363 17635 29823 14913 16974 21170 7486 101488 1.19_466.38 37692 63741 28734 19901 34861 27254 2925 34876 1.19_394.34 22551 28500 35262 28049 20194 27622 9540 44532 1.19_153.12 2303 9054 2428 8250 9478 15874 5351 5696 1.19_276.21 4929 24538 10616 28248 15360 40428 3986 13712 1.19_594.42 19978 17805 13650 4884 21064 13276 3331 1.19_550.39 21002 19171 14533 5699 21831 13594 2094 3850 1.19_307.16 46390 60106 42059 40940 46277 55270 32420 1.2_524.31 5999 40472 38820 13710 11425 20581 8110 11567 1.2_696.51 50263 29319 35526 5973 29849 22419 5411 1.2_480.29 4467 21524 21820 9509 6910 10630 5656 6580 1.2_277.23 32559 5642 4079 6209 4219 8470 2436 4206 1.2_317.19 10724 18108 4641 12989 17426 13101 13051 1.2_510.4 35997 60466 29776 17371 37909 27779 3612 43644 1.2_510.42 35997 60466 29776 17371 37909 27779 3612 43644 1.2_624.45 36253 48996 41396 10526 61343 34550 2932 1.2_275.16 13328 72806 24331 21912 21291 5235 13667 5944 1.2_569.38 23433 20098 17882 6258 10896 9605 3575 5051 1.2_381.25 3103 19429 3550 8345 20735 31415 9401 1.21_568.34 6702 58283 53898 17486 17382 29333 9866 13170 1.21_670.49 15016 19353 15087 6058 16501 12910 4871 1.21_482.39 21357 26268 40047 22587 26004 28952 6927 74876 1.21_626.46 20181 31242 21961 8594 26285 19111 5130 1.21_109.1 6932 4094 6447 6637 10943 2841 5799 6510 1.21_468.38 10706 17013 29806 12241 17684 18250 6245 101332 1.21_83.08 6337 5072 5769 10457 3215 1.21_440.31 9222 33382 21117 7273 26917 18639 7888 54552 1.21_380.33 23120 21275 6996 15118 16455 11856 8811 66420 1.21_298.24 3009 17975 4534 16259 16687 28173 3029 13358 1.21_616.45 4960 21736 19337 7279 23485 27058 6034 33267 1.21_612.37 7672 70493 64933 19924 18713 34511 10728 16521 1.21_136.12 5495 4575 6230 9299 2775 1.21_360.24 57185 325231 307764 442141 54914 137402 30399 1.21_320.18 6024 18810 23595 15413 12615 14247 11073 10856 1.21_712.49 19216 20043 17292 4891 23949 14820 2568 1.22_754.5 13251 8110 7547 2297 8704 6358 3373 1.22_274.13 2035 4400 104761 97575 96932 2961 48864 40456 1.22_554.42 26791 44441 26423 12124 31761 23091 3236 46911 1.22_554.44 26791 44441 26423 12124 31761 23091 3236 46911 1.22_674.5 4899 13128 12491 4404 16143 22291 3907 28068 1.22_437.23 33915 4374 4269 3112 3462 3059 2501 3857 1.22_121.1 11537 4490 10622 11313 18357 3479 6733 7686 1.22_496.4 11538 9698 16982 7724 10557 10661 2430 51881 1.22_387.19 7260 17835 1042383 931785 1097688 36047 895877 310444 1.22_668.48 27374 31915 27133 6939 38108 24204 2236 1.22_588.39 5955 8637 8067 2801 20123 13370 2791 129829 1.22_304.17 3676 26291 50135 35997 36395 39734 33164 11807 1.23_630.39 11733 11663 46318 29062 58078 9312 18146 7139 1.23_526.41 22035 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147289 58276 21862 27010 28253 10171 19416 1.49_368.23 24201 19031 11464 25966 9281 6436 12232 1.49_474.28 2999 13340 20862 6254 25663 19104 6266 9333 1.49_460.28 11506 99506 151570 25436 96526 12204 4517 42632 1.49_470.3 2657 154672 66416 27846 107084 30684 12243 18380 1.5_416.27 14550 100709 139492 31186 99268 73262 20416 21489 1.5_602.38 32902 35128 13693 58824 34907 12934 16880 1.5_859.31 4000 22140 12539 2294 10855 14737 1.5_516.34 8854 10536 5364 16254 9267 5117 36368 7461 1.5_823.51 2355 7792 9835 2905 9690 9239 8390 1.5_139.1 48058 33989 3629 4893 4057 3693 2905 29778 4346 1.5_637.47 21619 26725 15695 22668 46638 16227 1.51_601.94 8792 11780 7441 8243 16338 5968 1.51_297.21 5988 10104 13125 7829 5913 15447 10368 1.51_202.12 3380 100416 39730 17982 34805 135403 57353 165312 407376 1.51_412.25 2174 45417 31941 11996 48444 14014 6192 11036 1.51_504.31 8445 70785 124336 16986 72962 229426 4340 50498 1.51_620.38 3911 19643 23346 8823 19513 17040 3608 36421 1.52_227.16 2197 20306 26663 10650 16621 13693 10032 13425 78884 1.52_618.38 2877 8849 12426 3309 27419 11246 2583 19305 1.52_621.39 2455 7013 8804 3614 10988 9885 2237 12008 1.52_188.09 32283 605893 522676 142163 408220 989228 146429 17243 202246 1.52_659.48 24511 30452 16794 27762 54376 2288 22239 1.52_367.21 3867 3757 9042 6651 3578 2352 5871 1.52_923.01 3738 7581 16655 24611 36822 4265 5291 3522 1.52_648.41 33240 10096 10869 2021 15423 10582 3299 13064 3029 1.52_419.17 2234 54527 65561 33262 112802 118192 29295 10542 1.52_623.45 14921 20499 10870 16660 28462 11193 1.52_568.45 3740 5606 4249 8157 23213 8017 1.52_559.34 35277 14707 5581 24171 18985 5514 67096 1.52_659.98 17826 20729 11865 20970 37067 15059 1.52_179.08 37753 3103 2034 18529 1.53_625.16 111506 16725 3824 14723 69768 6154 1.53_632.37 4199 27160 46243 5527 28975 6402 7429 1.53_438.07 20126 5914 2549 5126 14045 3603 1.53_574.28 2771 15774 12465 3661 11734 23958 3105 1.53_544.31 4648 22307 46692 6853 30770 9518 3601 8300 1.53_402.26 7276 23376 30584 8259 38947 11152 5346 10077 1.54_383.17 14613 5428 7972 5475 13929 14375 4382 12746 1.54_645.46 17069 22454 11007 19137 34169 18530 1.54_681.49 24018 31396 15070 29568 52268 30199 1.54_720.44 2528 31806 41047 6812 17173 6402 13287 1.54_533.34 6945 10043 4218 8345 8184 2453 6860 31547 1.54_402.24 7276 31183 9581 8259 98872 24429 5346 10077 1.54_456.28 2984 56614 35811 11347 56743 15688 6469 12340 1.54_548.34 6172 49901 93042 11481 53988 278668 3528 56456 1.54_530.32 2047 13196 15003 4492 27320 13203 2755 17483 1.54_676.39 2823 30604 51545 6025 29391 6060 13911 1.54_232.11 5694 3633 2429 3190 11340 4697 1.55_818.5 2071 9336 12150 2979 13944 6645 5132 1.55_457.13 53233 7343 2153 4192 4682 1.55_458.29 2420 13166 18036 10008 23286 17437 7629 8260 2021 1.55_189.1 4277 71810 54432 16149 44812 108793 16214 7574 1.55_354.22 12683 10322 5482 16198 7080 3844 9845 1.55_143.12 2399 10824 47478 16601 4892 1.55_158.08 3899 25832 37216 8436 39102 35015 1.55_644.4 7792 7657 2112 8842 4523 3039 1.55_667.48 15697 19418 8614 14375 27117 19993 1.55_561.35 3116 4561 7056 2105 7126 6642 10835 1.55_446.29 6522 28999 40431 12848 41048 13723 6956 8395 1.55_350.21 9161 6032 6619 10250 1.55_667.98 10080 13896 6647 11211 18985 14370 1.55_850.53 15172 12827 3683 11154 15963 3703 7964 1.55_638.44 10046 17660 5570 22887 16764 12036 1.55_704.01 15850 19999 9105 18067 30214 24059 1.55_119.05 14207 9648 3628 9465 10106 2857 3614 1.55_500.28 2890 50505 40635 10468 47944 12429 5411 10555 1.56_212.16 4795 11939 11525 7304 190743 192033 7473 7981 1.56_441.15 56134 28934 17579 33587 40571 14864 5905 1.56_401.16 363254 195272 110308 270933 280931 75033 54641 1.56_157.08 4822 4626 3849 4612 3942 3120 5752 9175 1.56_365.21 20692 13828 7079 12650 5600 8252 9108 2395 1.56_356.23 2741 18765 24312 13948 48892 19925 9287 27364 1.56_806.52 8284 11494 3375 10589 5874 7334 1.56_528.33 13550 11704 3633 15958 10981 3311 6865 1.56_420.25 7114 10272 4127 11568 15746 10237 19464 1.56_413.25 10885 10960 4143 14728 5013 2331 8311 1.56_464.3 5554 8675 3031 9920 10380 2461 7666 1.56_546.34 12040 16685 5536 17785 13821 4335 8829 1.56_689.99 8573 10502 5282 8986 15182 13362 1.57_530.34 13196 15003 4492 27320 13203 2755 17483 1.57_689.49 12713 15548 7899 11996 21297 19447 1.57_726.02 13518 14467 7209 14270 23030 21278 1.57_633.41 8252 11146 2326 9805 4990 6023 1.57_453.36 2752 17786 21535 5149 7787 6258 10634 4511 1.57_454.27 2304 23082 9678 10391 16757 7866 10364 11338 1.57_738.46 2577 7130 27099 2578 23506 9999 6145 1.57_555.35 4829 7337 2248 7350 7924 2106 7709 1.57_258.2 5046 4306 3149 2623 2980 2245 4344 2957 1.57_866.53 9702 13088 3860 15308 13115 2465 10588 1.57_490.31 5810 29065 48002 11815 37463 14583 6794 6889 1.57_442.28 24113 20432 8293 28178 13794 4792 13431 1.57_491.3 2369 8543 12383 3847 15984 4683 2979 1.58_316.21 3105 5207 2304 4745 4572 2187 8145 34614 1.58_478.3 2115 4269 6471 2863 5940 6541 4283 1.58_711.5 9405 12858 6293 10182 16611 13799 1.58_747.53 11977 15471 6680 13966 24675 21267 1.58_764.48 23670 27405 4495 13485 5696 10778 1.58_748.03 9241 10996 5682 11971 18272 16924 1.58_636.4 2753 37412 212273 8431 287944 236288 3139 8328 1.58_666.42 2392 5805 16105 2590 14749 8146 6832 1.58_371.24 3634 3334 26894 2168 9847 8010 2813 1.58_465.28 6951 11866 14546 8388 23313 28209 2890 11726 1.58_706.44 7703 11326 2379 23754 8610 15705 1.58_662.41 8106 11541 2710 27868 10008 2092 15787 1.58_254.16 2510 4282 2921 2923 4907 4713 2441 5222 7746 1.58_261.16 13233 4810 4392 4103 3837 2259 24253 19595 1.58_569.36 3445 7250 10327 2808 10024 13603 2757 8155 1.58_622.39 3171 9608 20550 4410 16788 9448 2113 6112 1.58_268.01 2887 5564 3486 4768 4421 3777 2837 2596 1.58_457.28 13835 12409 4216 17128 5120 2299 8464 14335 1.58_910.56 6387 10222 2149 10600 8720 8699 1.59_198.15 7853 9579 7296 5713 6621 5058 8721 1.59_406.24 22907 41625 5937 29590 41943 21158 6985 2325 1.59_558.35 124279 47322 18794 80334 22741 9003 17043 1.59_712.01 7174 8742 4964 7881 12337 10513 1.59_752.48 11559 19323 4174 21097 16436 2001 7001 1.59_725.51 17261 61473 9025 55046 29313 27675 1.59_534.33 4694 23205 35832 9226 44196 13300 4932 6872 1.59_420.76 4260 4870 11318 10014 1.59_734.02 4666 6184 2893 6159 9103 8254 1.59_808.51 14354 16986 3341 10690 5563 9762 1.59_486.3 18442 16848 6211 22480 14872 3421 11901 1.59_634.39 11528 17579 4272 17284 12434 3631 6547 1.59_750.47 5921 9241 2181 18571 6998 15109 1.59_215.1 69445 9422 8951 7150 78751 20419 1.59_613.38 2315 6089 10263 2817 9403 13094 2640 9720 1.6_571.33 30811 23218 13563 23078 36619 11797 20201 1.6_415.27 2239 4831 33889 2587 28785 21910 2999 4217 1.6_770.05 6420 8486 3688 9607 12672 13577 1.6_606.37 2736 20498 34426 10347 37514 19124 4719 14821 1.6_446.27 6522 22695 63259 12848 92342 17104 6956 8395 10772 1.6_792.06 4697 6432 2445 6549 9708 10234 1.6_366.21 11995 10541 7480 12830 6601 10283 12280 1.6_435.28 5099 5272 2246 8535 2451 7942 1.6_578.36 3614 15619 24569 7694 24252 11558 3504 5888 1.6_694.44 2495 9204 29984 4054 28112 13142 7469 1.6_264.14 2660 2150 12177 20184 1.6_301.15 8623 6985 7836 7058 6874 8017 5570 149849 67741 1.6_678.42 11843 19270 4197 15302 13025 2480 5905 1.6_932.55 4656 8061 2089 6258 5297 7090 1.6_756.03 3537 5206 2199 3940 6251 7002 1.6_410.24 31907 17853 23331 26581 10155 28108 28535 1.6_371.17 5883 4882 6054 4411 10592 7407 6506 4089 1.61_640.4 6861 8305 2048 7724 9377 8683 1.61_938.56 7917 7422 5807 7107 1.61_215.17 3145 2698 12852 2065 16158 29746 1.61_894.54 6449 9820 2292 8699 6919 7741 1.61_950.58 9190 8911 5282 5821 1.61_319.15 12277 7309 5556 3992 8190 2932 2306 50501 21359 1.61_309.04 10833 2518 3914 2301 2997 3167 3787 2966 1.61_473.95 18806 63466 38854 50303 62392 28715 21094 8203 1.61_358.21 5876 36318 67796 20003 83056 24775 6878 13621 25752 1.61_545.33 10644 13689 2672 12028 3987 7971 1.61_814.08 2800 5396 2121 5320 5935 9527 1.61_314.18 4344 31613 40702 22485 50997 17447 10310 13028 1.61_643.39 6668 7820 2165 8090 6562 4859 1.61_826.52 7261 25191 13825 4700 1.61_501.3 14112 11298 3637 15178 51930 9215 11858 1.61_686.41 14553 8593 4001 13455 5842 3755 1.62_746.46 7331 11667 2678 11326 6591 4197 1.62_377.21 6111 8788 6764 7378 10938 23398 9256 25142 13183 1.62_796.5 8728 17355 2713 17338 13041 9851 1.62_591.37 8697 12918 4161 14381 16709 3182 11144 1.62_585.36 5046 7737 2579 6667 7007 5548 1.62_201.11 6129 11110 3904 10499 4987 3880 3670 12635 22397 1.62_183.11 2786 6225 4798 5803 11115 24675 13253 1.62_270.19 20362 11078 10113 18659 14630 9065 17661 2098 1.62_245.19 36089 42319 18252 14952 19552 16256 20510 13867 1.62_862.52 5525 14283 2567 12588 8020 5902 1.62_460.3 4993 47895 83542 32681 118341 162303 29963 42632 1.62_502.31 2514 12292 19368 6893 20076 15016 5860 8175 2834 1.63_635.39 6139 11735 2619 11195 12340 2128 9246 1.63_311.2 13120 15086 14905 34591 51599 19946 14370 13997 1.63_633.38 9560 15964 2012 10156 4990 5243 1.63_834.51 6908 14021 2859 11672 9251 7477 1.63_680.43 29220 214331 7403 241125 159347 2852 8533 1.63_191.09 2680 10843 5380 8450 6475 3773 7106 40699 32144 1.63_355.23 24908 25448 24148 52026 89774 37245 26320 1.63_244.19 220682 289316 112302 94611 126939 102520 125397 9463 1.63_878.53 5081 10318 8269 7182 1.64_589.35 8972 15341 2999 13940 12562 7324 1.64_506.32 5606 12493 2920 22694 14339 2362 5798 1.64_297.17 12790 16017 9285 17109 6582 4022 6397 1.64_285.1 2068 5177 5173 373862 474458 155598 1.64_194.08 30813 2106 2815 40554 5755 1.64_399.26 27014 27834 23356 54076 85009 25616 26256 1.64_170.12 4825 8483 4744 9900 32252 11515 14652 1.64_414.26 13151 15109 8399 17845 15061 7549 7717 2540 1.64_504.33 3117 62356 128700 37175 172087 229426 31399 50498 40009 1.65_250.12 6669 3298 2163 5451 27776 1.65_137.07 24871 3458 54294 58167 3091 169657 19057 1.65_724.46 22525 172461 4775 158676 84581 7703 1.65_247.13 5474 4151 2687 4156 2459 2145 2519 177135 45520 1.65_226.13 5484 3405 7460 4105 13538 4299 5476 1.65_443.28 23734 24779 14528 38492 61456 15008 19496 1.65_204.12 88022 11381 2519 3940 10497 6133 3625 14485 22317 1.65_550.36 5578 13547 2700 16884 18747 2162 6234 1.66_812.51 43333 33117 4425 5803 1.66_116.07 9225 19436 15263 10808 41496 13204 5167 6945 1.66_270.17 2555 20362 8767 9716 18659 14630 7602 17661 3505 1.66_151.1 279364 111542 9073 44116 123178 192356 4726 46608 59019 1.66_97.04 5197 5168 181736 2163 26456 42623 1.67_768.49 13625 96460 3358 76946 41308 5534 1.67_487.31 11122 17743 6439 25993 31318 4846 8819 1.67_326.38 20894 2623 2336 9068 15033 11264 8049 1.67_393.26 4216 29772 2606 23788 15754 2641 1.68_201.07 6129 5969 2156 2015 4846 39114 23409 1.68_330.21 16977 13391 6279 28128 7411 4481 6200 1.68_229.1 3057 28017 2900 3572 10440 7924 239358 3900 1.69_432.26 31266 6684 8807 3782 12024 4127 2736 5657 3961 1.69_548.36 71442 164581 36207 218541 278668 30613 56456 1.69_165.11 104256 13443 46708 31530 38638 14357 36292 12674 13362 1.69_531.33 6383 12469 3483 17150 18405 2931 5721 1.69_111.06 149890 6377 75956 9701 2803 72143 56410 1.7_142.09 8413 7732 12571 13157 1.7_112.07 28639 5846 5139 46886 24424 1.7_360.36 4103 4495 2007 9790 8641 21462 12044 1.7_345.22 8602 3762 123654 9920 209345 4421 11674 2826 1.72_462.29 8820 18834 2952 34393 6129 2010 3058 1.72_508.33 10279 9092 2979 9615 12044 2231 8763 2108 1.72_564.35 10614 4700 9218 2196 10982 5914 4003 19630 1.72_209.14 326065 27154 24978 35238 24065 53584 25678 29795 56543 1.72_253.16 12482 14846 15106 11190 16119 28525 10314 27304 2981 1.72_138.06 25971 6511 2131 4811 7426 2439 14550 6478 1.73_592.39 67806 208783 32106 273220 267941 26719 48820 1.73_279.14 27644 6684 5973 4042 5476 3217 2274 4433 5119 1.73_180.07 47336 2023 66801 19399 1.73_594.38 5827 15601 2340 8717 17138 2391 4520 1.73_259.25 9542 15828 230717 102202 1.74_368.42 14913 25166 18403 18554 58826 36732 1.74_195.12 28418 1492711 2010076 1170206 1961409 1966065 882249 1425924 1809021 1.74_174.07 7077 5781 13240 3673 8087 10485 1.74_547.36 7311 10294 3240 10628 12177 3099 7120 2926 1.74_212.15 3830 148154 188657 111845 190743 192033 88284 142081 174864 1.74_213.15 14554 18205 11731 17744 18258 9363 15014 15779 1.74_203.1 19715 22708 29504 3112 17064 155394 2654 1.75_169.1 2704 9069 9527 10920 7486 32207 24741 1.75_298.35 2163 4080 5016 8672 28179 19011 1.75_333.19 6260 4721 7005 8709 13692 12939 4541 2054 1.75_240.16 5009 118714 103862 49535 83383 89440 35845 71802 1.75_332.33 14214 23340 6872 29222 27065 55398 24789 1.75_185.08 5453 2953 6639 31551 11084 1.76_233.08 107233 33670 11438 13474 14272 7822 8326 20572 1.76_166.09 11770 2163 2370 5445 3013 2757 16917 30396 1.76_202.09 5571 4847 4341 8090 2728 8231 5853 1.77_207.12 24112 5037 4014 2768 6384 3664 2021 4756 2872 1.77_217.11 22672 143047 222585 3050 157392 223156 107367 63180 6234 1.77_235.12 171312 8295 6557 6973 9743 4863 5444 6338 3804 1.77_261.13 8103 137751 112549 47920 114791 73825 25616 87792 1.77_163.09 10101 64446 3761 3985 6725 3234 3232 54287 62011 1.77_125.08 436356 25547 145272 35634 8415 6447 302347 130638 1.77_139.09 7328 114236 227451 33957 332905 5093 18308 370280 144036 1.77_206.09 5260 16532 2921 6857 10636 3491 1.77_636.42 57852 32242 27232 287944 236288 24013 40589 1.78_241.16 19720 17439 8149 23106 13803 5933 12665 1.79_186.08 72249 4086 3255 19216 2007 1.79_175.09 6207 2932 2584 7057 2934 2437 9680 15162 1.79_326.21 2408 4646 5613 2835 19706 3932 2006 10071 1.79_153.1 47482 4503 3435 3498 4550 3325 25645 15836 1.79_218.1 19747 16186 11863 8386 19109 20115 11740 69688 4725 1.8_133.09 24581 34281 20327 35997 29144 16899 19574 23677 1.8_283.17 10764 522274 436369 122278 719296 199568 98823 167321 1.81_166.1 5504 6699 4879 3076 3594 3795 16917 31611 1.81_231.22 266691 43637 6155 25807 16262 4762 267028 1.82_277.11 11379 122670 23644 7258 14367 8845 3633 7171 1.82_321.14 9056 111809 21425 3354 14136 4440 22341 17169 1.82_86.06 18197 35865 11770 42636 22949 1.82_223.11 69692 4131 2316 2150 4798 4440 1.83_220.12 9622 10139 5258 3931 29920 203182 1.83_107.07 5129 5120 4771 4072 5389 3902 6520 8234 1.83_284.33 9979 11682 4349 15837 8290 28600 1.83_111.09 63591 2948 2458 3989 3376 2687 2502 2594 1.84_123.06 5405 2320 2257 35700 45996 1.84_196.13 3231 127778 175191 101150 173278 172289 75100 123654 2722 1.85_176.13 5957 9202 6940 10922 13319 4362 4841 23940 1.85_123.08 62710 7879 4964 5254 6511 8639 6070 13908 1.86_256.17 10541 470691 407713 189561 542583 345308 134879 228071 2048 1.86_282.19 5507 10555 6491 9539 11030 5158 4280 2391 1.86_349.18 3523 27494 35560 3750 46276 6530 2276 18690 1.87_418.26 12968 21630 4326 47752 6648 2411 2868 2877 1.87_177.11 30989 16956 8253 17202 14009 6245 27981 3439 1.88_374.24 13976 20071 5511 46432 6796 3018 4198 5805 1.88_140.08 3957 13440 19645 5966 28721 2608 34974 10398 1.89_152.1 24419 8617 3340 8729 12405 5325 1.89_199.15 25177 13683 41041 44017 14811 1.89_258.19 8201 4083 4427 7048 7515 5707 4853 1.9_262.14 15874 13287 5819 8528 9257 3433 10525 3010 1.9_300.2 17521 1061199 886434 256780 1476847 430037 208383 362817 2636 1.91_126.07 8751 2593 11539 2828 21503 8022 1.91_680.44 48648 9896 22031 17078 110630 18582 34316 1.91_200.14 100902 52149 161568 178626 59532 2997 1.92_239.15 34696 1096497 967753 461381 1365817 845052 333960 569800 22416 1.92_327.2 3338 101682 109845 22109 192992 38058 17971 44330 1.92_372.23 2677 5753 3422 2894 10731 3878 6582 1.92_305.16 6251 111798 86558 16584 115078 31455 10144 51304 2356 1.93_155.08 51487 20703 17028 5624 208193 17207 1.94_164.09 8429 2383 192301 170805 128900 1.95_114.06 108199 21131 6147 19055 3781 5450 7210 128759 155496 1.95_323.17 11509 11099 3853 17149 3897 3392 3003 1.96_329.12 2513 3561 3727 21111 1.96_128.07 7515 9593 18316 12721 1.96_208.1 25134 6999 32483 9172 1.96_146.06 3182 2074 4548 42497 2355 29356 1.97_228.27 10429 22670 17107 18821 17388 5849 39121 1.97_219.12 59498 39662 3778 2459 4204 4116 2657 62092 2535 1.99_344.23 18750 741448 793136 151077 1341202 259848 126939 307012 2439 2_189.05 2607 9131 12400 8878 2451 5861 2039 14941 2_416.23 3188 44414 115174 39597 67220 70998 22391 31787 8540 2.02_258.28 7775 21389 7729 9078 23760 5805 16946 2.03_388.25 16908 475981 542721 89401 1049136 152151 60335 231919 2113 2.04_188.09 22810 101463 6284 106735 4117 11910 2005 259981 219777 2.05_390.26 15257 3426 3496 29785 5051 2670 9517 21551 2.06_681.45 16966 3630 4234 5625 5205 6203 11992 2.07_472.28 4892 42341 45309 8691 65594 7571 5438 5090 2.07_384.22 3130 17010 17901 5443 31650 5135 3487 3425 2.08_367.19 3889 10516 12225 3593 18596 3119 2180 3186 2.08_432.28 12817 310045 324172 52681 810178 90728 32593 205389 2155 2.09_190.1 4942 2655 7901 13018 2.09_242.28 5086 2927 4291 8326 7581 2.09_677.48 7092 21539 2730 11916 3470 8485 2.1_371.23 18014 6007 9729 55887 8553 3665 9904 2.11_725.47 13246 3455 5160 4881 4762 4783 9887 2.11_89.07 5704 23719 3162 19737 24240 14397 7321 7335 2.12_228.08 2359 18663 21310 28135 32069 2.12_724.47 35273 8339 9293 11492 11630 12550 24550 2.13_279.17 32506 74669 7961 80509 33800 6948 22396 15725 2.13_159.11 18531 12959 33940 14479 10497 16126 2.14_340.2 2293 10237 13782 3996 19182 3674 2701 2986 2.14_476.31 8851 196081 33018 29650 207287 57371 19874 191584 176340 2.14_234.17 15608 17845 8164 13862 17889 4362 10708 8121 2.15_231.25 7545 4747 5267 11762 3277 9342 2.16_428.25 4236 32254 33680 8353 47037 6990 4906 3767 3388 2.16_114.07 8099 38548 14841 4240 5664 7955 15265 2.16_295.15 46627 24438 9773 29553 34543 5909 30298 2.16_473.28 10879 7273 2633 10315 2348 2100 2.17_400.38 4921 6367 10527 34640 2.18_189.1 3201 30228 2864 11355 4382 2996 44878 22628 2.18_560.33 5050 48888 41926 7801 57667 6832 4699 4234 2.18_173.13 15908 42824 121310 25148 12085 10317 2.2_521.34 2219 32152 6079 5078 43366 10189 3523 37532 32728 2.21_285.23 4878 10585 5194 23613 9196 4753 10045 2.21_520.33 6381 127187 22145 19298 159792 40858 12444 156170 2.21_371.23 18014 6007 9729 13626 3687 3665 9904 2.24_516.3 5127 48407 46288 8558 67476 7370 4935 4610 2447 2.25_477.31 2652 42659 8014 6321 33699 4858 4658 40147 2.26_86.06 17061 151213 137947 10024 217754 211601 2.26_604.35 4968 54138 37690 7655 52078 5927 4396 4599 2.27_228.19 9531 16669 8764 60681 15188 7337 33309 3788 2.27_137.07 31913 48065 3098 2092 55915 50720 2.28_174.11 5405 15029 7625 5850 2.28_156.08 12524 3953 18256 21541 20156 2.28_812.52 12993 4001 4166 5382 5049 4116 9029 2.29_131.08 3593 197956 186982 12541 283487 269581 2.29_115.06 5259 41619 38004 3140 57688 54782 2.29_227.17 60729 120334 57285 460493 106498 42866 238405 13435 2.32_174.14 8304 7696 2159 7869 9789 2612 5995 4086 2.33_208.15 2586 5199 6334 10002 12547 5822 2890 2.33_178.07 110776 3864 47161 27864 2.33_564.36 5152 89612 14851 11903 80700 29191 9217 101669 2.34_629.33 9990 2963 4303 2904 9650 2915 5355 2.34_279.17 91396 74669 18939 80509 89111 16935 57152 35037 2.36_443.24 9151 4868 4076 3869 7924 7525 2.37_437.29 11903 4475 4799 7629 7551 5212 8749 2.37_459.3 9997 4351 5437 7652 17995 5124 7274 2.38_699.41 18954 5897 4166 20565 19184 3275 10891 2.38_648.38 5021 49928 9991 6307 19906 4475 3360 3869 2.38_155.08 140439 7454 210993 9469 6177 7078 239220 7314 2.4_369.38 7674 3061 10258 25494 43482 24071 2.41_281.16 5889 5492 4434 2794 7072 6508 2388 4547 2.42_565.36 24790 4531 3462 22006 3603 2755 26323 2.42_221.13 106456 3009 6594 17202 14990 29365 2.42_200.23 12081 20429 12572 18767 7893 3867 10912 2.44_562.89 2186 2634 8573 12593 5980 2.45_209.1 9473 4793 2013 2999 2563 3678 2894 2.46_114.06 80429 720029 665096 42697 3507 3404 4675 1063234 155496 2.47_163.09 4058 22769 5701 106594 170842 2.47_316.32 31574 19542 3403 18009 31223 10448 2.49_160.17 8752 7926 3999 12486 5932 2570 12529 16028 2.53_166.09 51331 12000 7046 2883 3531 3125 90227 29310 2.53_696.93 7375 9760 7277 8330 9845 5111 2.54_249.15 39380 5910 10167 4108 26799 17324 4416 12545 53067 2.56_126.07 2577 2750 13345 5839 28154 2.56_230.25 35515 73440 26705 33691 64713 24935 46145 5425 2.56_217.1 7121 3872 2219 2102 2216 2123 2106 200189 46125 2.57_481.32 8102 3355 3789 6399 6454 3886 4247 2.58_652.41 2562 46299 8073 5782 28876 8722 4735 37258 31654 2.58_199.11 3634 5371 6425 5138 8630 6213 2.58_692.41 4069 42524 7277 5046 12649 2047 2675 2885 2.59_141.07 50180 13262 37791 20601 2.6_132.07 16024 20295 5296 24447 42485 18401 2.61_185.09 29972 21807 10763 2268 18206 11084 2.61_346.2 10174 3135 10361 9121 5976 2.62_310.13 6505 37976 6939 43304 2596 6776 46688 23285 2.62_288.14 12695 3869 16724 23983 10881 2.62_430.39 15302 2047 22791 15846 87826 2.62_288.29 111101 76452 12289 45037 136595 10724 52900 2.62_375.21 6600 3089 11206 6833 4400 2.63_302.23 9495 4314 2345 5184 5438 5348 2642 2.64_270.13 23518 5924 30789 45288 18417 2.66_230.14 2887 5265 4914 109019 30840 3734 2415 2715 2.66_169.1 2322 108803 15306 9557 6672 25550 9381 2.68_180.1 21273 9419 31971 7030 2.68_232.12 21742 44443 33372 5513 2.68_289.29 20351 6833 2338 9060 6230 2297 9908 2.69_211.11 6407 23098 20184 5194 2.71_246.14 9724 14950 7137 15171 3442 2.71_223.12 53922 2149 2270 5129 20374 2.71_736.43 2861 29749 4737 3788 7648 2122 2130 2.71_503.33 6664 2597 2804 4818 4996 2793 3946 2.71_155.15 16804 21031 5398 70787 19498 9487 39700 24201 2.72_533.31 7590 13483 4820 12533 12674 3032 3267 2.72_139.08 2325 5586 6534 5615 10668 3620 2.72_175.1 3585 8371 3535 2474 10168 15162 2.73_696.44 28529 4753 3472 14086 7739 3063 17613 2.73_279.17 13873 10481 4276 9191 12384 3355 10691 2.73_218.21 25527 33884 5057 18759 33902 4470 17222 3620 2.77_142.09 10402 5456 9128 4140 2.79_297.1 30451 6077 2704 2500 85442 80732 18127 2639 2.79_216.12 7191 4435 2942 60081 56085 2576 2.81_235.11 106500 5637 2021 2020 5224 5822 37134 2.82_310.14 5881 46308 5865 7907 2729 46688 91855 2.84_780.46 19324 2499 2046 4201 2.89_298.1 5795 5553 7556 6526 62940 10628 2996 56183 2.89_467.31 5664 3454 19545 5189 2891 2.91_288.29 29256 8672 3228 19019 31532 2867 21737 11856 2.91_251.11 3204 5557 2242 14844 25639 2.91_244.26 17993 5112 3173 19538 11651 7330 2.92_329.11 4165 4387 34021 4038 2408 3997 2.92_148.09 6559 11762 5286 9594 5611 2.93_277.24 7884 6326 2225 11449 3620 2.94_230.14 2393 6279 7132 74811 21596 3183 4334 2715 2.94_132.07 8332 11509 13830 2610 39246 2.97_183.11 11294 7496 19757 18762 2.98_231.14 6814 2329 11360 4086 10798 2419 3.02_264.21 6861 6847 10134 2521 10983 9325 2027 5338 3.03_185.1 8366 6476 6022 2715 14946 3.05_360.22 2303 8712 3410 14175 9195 2173 2169 3.05_263.2 36636 45317 71083 15303 69167 65399 14487 36559 27994 3.08_159.09 407549 6957 13813 65291 3284 577848 412953 3.08_140.08 2377 16412 3047 5804 2797 2212 2369 11489 10398 3.09_316.21 139108 103513 34004 142704 112040 27447 85986 3183 3.11_172.1 16154 9218 19144 7795 3.13_244.16 2910 28542 15108 3766 54110 3.18_562.89 10532 6146 6935 6610 4132 3.22_474.23 16681 25286 10855 16907 13297 5165 7642 3.22_166.09 13818 9393 3850 3043 2913 3272 43176 5990 3.25_245.15 4190 17483 11118 34206 19258 3.25_152.07 14468 3043 2120 10815 2976 3.26_340.26 3632 4516 10476 12600 13468 3.29_230.25 10221 5399 4826 5936 6028 5585 24935 4511 5989 3.29_188.2 27915 3825 7256 3247 5045 4565 56541 48013 3.3_280.12 17480 9063 9294 13959 6391 3.32_182.1 17928 22999 6278 99377 6558 3.36_214.11 4661 6218 2595 11012 3662 3.48_272.19 28063 7732 8206 26746 17102 4819 23026 20096 3.59_923.01 21544 13347 57565 16555 53543 3615 4937 3.59_283.16 3093 2191 19327 3850 3.6_187.14 8470 13739 4799 3134 7939 3.62_280.12 17480 10778 5595 17926 6391 3.63_128.07 15781 18744 15616 2671 3.64_139.12 51919 6033 4966 4531 16025 2560 148367 570355 3.65_162.1 18518 13512 34188 31678 48028 3.75_138.09 7451 4967 5050 6137 2660 11084 16396 3.81_128.14 190651 76385 48351 9227 2654 2742 209226 268758 3.97_190.14 30897 44702 37000 67847 54010 23335 33154 27517 4.1_156.14 8965 13463 9096 3317 27856 16473 4.14_144.14 2777 1213597 1254587 1180542 1752975 1308900 865702 1258722 4.15_144.25 80503 83880 77788 125289 88092 54008 85042 4.15_145.14 106501 111014 106143 158466 117102 77474 112200 86486 4.16_287.27 458784 449070 321427 963377 405469 154197 520914 470257 4.16_537.25 165239 45808 29318 83506 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35923 53315 39546 375360 49293 29527 137792 771720 4.93_230.25 10301 13134 22610 24383 21361 22098 24935 8275 8843 4.94_111.09 13405 3563185 238227 130305 508069 832280 34844 4447735 4226844 4.95_475.32 32440 14837 9490 72442 11589 6627 103123 238909 4.96_136.06 15241 5468 11475 11434 4.97_511.4 6517 7497 5344 38340 6782 3409 24706 57969 4.98_162.11 6623 4294 5996 5678 3371 4225 5_153.1 8351 8149 2023 3822 2158 3929 68589 107414 5.03_155.12 3054 359129 4583 6144 9465 5.03_90.06 250454 7959 4198 237195 141318 5.03_132.07 610570 19903 8983 2635 576022 361229 5.06_430.3 62417 3849 15733 7671 5.09_174.15 9688 6617 6383 13552 5221 5.09_500.19 4670 5185 4597 11067 5833 5.1_193.16 3120 10237 51037 32082 31712 61140 22964 4761 6607 5.1_116.11 4699 2123 2022 2342 11307 64607 5.11_192.16 92538 498894 321142 316402 638647 231315 66211 58614 5.11_399.36 5019 2385 30698 41458 5.12_56.05 7588 15516 11565 16724 5.12_166.08 3737 8277 14086 11731 5914 5.13_443.12 25945 166714 12185 25858 84420 5.13_347.06 23487 5301 4340 12112 5.13_255.07 10411 72763 25839 74674 5.13_464.18 3038 15654 6611 36113 3747 6667 15848 5.14_118.12 4541 593269 2917174 2438668 559735 156825 265431 1144174 751910 5.15_97.08 5823 1005349 77007 40016 2093173 368197 24262 1461492 2256762 5.16_224.12 7153 5282 15235 2246 2987 5.17_485.22 147046 107483 4609 2932 2093 5.17_118.22 32355 221973 183019 30417 74933 44059 5.18_119.13 40842 201795 167451 38667 11417 18253 78233 52708 5.18_426.16 44970 56577 11160 7198 14603 5.18_114.06 285586 16481 15566 10492 13544 11089 299030 64867 5.19_405.11 3078 3520 2288 21683 18419 3101 8126 5.19_923.01 8634 17013 88217 13217 40416 3289 4040 2697 9774 5.21_429.38 6333 2450 4049 22539 38931 5.21_371.33 4421 12875 6223 3045 15170 3935 77887 117305 5.22_268.1 2365 11158 17072 95473 5.22_922.36 7312 3831 10445 3201 9487 5.23_348.27 6768 5856 5428 7727 4781 5.23_518.32 9345 3546 2569 9117 3569 2461 5.24_160.11 28260 2847 4959 17154 19738 19177 312096 237320 5.24_187.08 20760 6024 17903 42455 31295 5.24_187.09 20760 6024 17903 42455 31295 5.24_137.05 2074 188657 73183 168004 184061 5.25_159.03 23284 14221 8024 14550 5.26_175.09 47381 17995 92780 53764 5.27_195.1 5065 15909 8790 3091 5710 7864 5.3_100.11 1897686 1318073 1001006 646106 202860 215314 2378860 1234951 5.31_236.15 39472 11326 19747 19045 5.31_562.34 13818 4321 3115 9468 3763 2290 5.32_55.06 14349 12072 8510 5728 18727 10530 5.33_762.56 4586 4717 4137 3140 2011 4192 6622 5.33_245.1 3555 6970 5078 12710 5.33_125.07 3738 3060 5391 3112 4901 8433 5.33_83.09 72855 49665 39916 26827 8093 9299 87269 47683 5.34_350.09 14196 29028 28915 22544 7971 8783 16617 14662 5.34_449.2 18916 38779 38372 29234 5471 6326 21869 18143 5.35_437.16 5462 6047 6223 4770 5126 2406 5.35_408.15 5071 28051 29049 22679 16850 19016 4151 7589 5.36_134.12 5905 21147 25734 55366 43275 88574 29068 30955 5.36_171.15 10189 14227 12409 15090 18267 9770 10063 12418 5.38_141.1 2019 6998 2059 2352 268870 9629 31205 40746 5.39_606.37 20448 5027 3769 12112 3911 2335 2193 5.4_650.4 21386 5765 3851 12454 3838 2357 2416 5.4_224.17 160725 6339 13936 14987 5.44_628.38 21021 5195 4002 11492 2060 2392 5.44_293.2 6504 2450 2379 34504 16173 5.45_104.11 29146 16636 11966 35186 19158 12718 18100 65750 5.45_584.36 19366 4643 3402 11175 2157 2322 5.45_303.2 227040 7471 20267 41754 38647 13189 342456 57724 5.47_211.15 45580 83542 58875 22830 2030 127698 161876 5.47_672.41 21288 5114 3489 10576 2740 5.48_738.45 14870 3625 3076 6375 2690 5.49_624.48 3332 7625 4923 13150 3099 23009 11523 5.49_566.43 2853 10894 5589 14426 2815 19002 10750 5.49_302.2 40679 186394 127880 267283 240381 79734 42490 68846 5.49_182.09 24842 7093 161114 130426 5.49_610.23 2949 4847 10054 10898 3904 5.51_448.12 2101 21024 2616 3511 14159 5.52_164.06 159973 2168 74945 80025 5.53_123.09 14925 6434 3580 26462 5385 21880 13110 5.54_158.15 57115 70811 43773 72959 57257 29478 37245 48133 5.55_210.16 182799 12862 10556 11060 5.56_466.19 5281 3400 4037 6602 6758 3550 4385 5.56_110.07 14326 2223 2762 2701 2773 3033 24835 11205 5.58_140.08 13052 13772 9152 298048 28201 7991 4183 108469 266170 5.58_565.32 5865 5360 2330 4505 3650 3793 3962 5.59_178.09 5368 9691 4796 19991 22106 5.61_258.17 8551 22505 19145 28444 21084 9194 10440 8149 5.62_209.13 21258 4584 2121 9629 5957 5.63_679.5 5909 4916 2399 76024 4727 85447 330713 5.65_449.14 35214 3494 6283 12148 24302 18336 5.67_202.18 3454 136947 243961 142422 462115 347080 124212 94581 138219 5.67_198.11 4568 3099 21130 36182 5.67_737.56 4820 38025 61698 134530 5.68_165.11 42726 4414 3033 2926 2933 3114 3310 3683 4193 5.69_510.21 2634 6805 4279 10962 9495 3700 2825 5.7_679 5220 4478 3740 11047 7776 5.71_142.11 40836 3337 7281 18746 40730 22454 5.72_251.15 3281 4619 5589 10463 3594 5.74_197.13 12790 35190 23606 66845 21339 5.78_585.37 30589 22376 8747 34228 32959 8454 22626 16479 5.79_109.08 30912 4997 7760 78063 3702 45435 53244 5.81_224.13 27172 15582 9381 9252 5.81_293.19 4404 3944 2069 7422 8090 2461 4067 2675 5.81_203.08 2895 4399 14299 20574 45515 5.87_155.08 11369 2442 2287 9494 5061 5.89_205.1 13551 6795 2182 17340 11814 5.91_130.1 2351 3725 2398 5164 5966 4073 14550 23073 5.92_185.16 4221 12252 6918 13657 10459 6679 8975 23408 5.93_534.31 3433 5099 6626 9060 3615 2014 5967 7888 5.93_578.34 2637 3550 4596 6293 2669 4328 5925 5.95_114.07 22810 4099 6256 4727 2609 2584 16708 11780 5.95_490.29 5863 6764 9093 13202 4783 2770 6302 9474 5.95_128.09 39414 5521 2751 20159 2495 56852 15703 5.97_207.12 4913 2760 14841 7513 3521 2249 5.98_446.26 7234 9218 10406 20352 7473 4137 7560 9996 6_421.1 6516 6658 3695 7713 5833 6_95.06 23871 2062 19009 13158 37766 34799 6_113.07 83277 7867 59936 40801 132385 122769 6_402.23 8893 12456 11596 25030 9786 5090 8453 12663 6.01_127.08 574386 77551 6421 1246109 30788 2779 838194 373088 6.01_435.12 21987 4235 2865 37142 2066 22350 11180 6.01_172.12 13163 3465 2514 4315 4059 2605 9369 6044 6.01_363.16 4756 3651 6603 6152 17643 5237 2833 3281 5775 6.02_170.1 16944 3061 5161 5103 6.02_114.06 22810 4099 6256 4727 2609 2584 27478 11780 6.03_358.21 10113 12621 11057 23750 10081 5052 9002 13060 6.09_314.18 8699 14524 5595 20503 8531 5060 8316 10545 6.09_297.15 3276 5678 2345 7429 3311 2028 4010 4092 6.09_355.21 2257 7390 3435 9940 4872 2398 3577 4960 6.09_319.14 7223 23640 10733 37097 13957 6823 6270 11190 6.1_172.13 11567 3465 2501 62207 17466 4357 16641 5707 6.1_165.11 10148 6967 4731 4757 58131 3667 2023 68692 68246 6.16_140.08 13052 5833 2254 5226 2342 4403 3093 6.17_183.11 214083 17278 141183 5319 2703791 2632557 6.2_137.11 2821 2185 30764 31010 6.21_491.15 4950 7517 21779 35330 6.23_235.12 14622 7329 3455 3832 2696 2602 2207 4091 3701 6.24_191.08 103485 9327 13015 120266 172432 6.24_258.1 6535 5710 22243 7107 6.26_243.13 10993 7503 3761 48371 29538 6.27_188.13 2779 19957 7364 16334 16083 6.29_381.19 8142 6436 36474 11484 6.31_352.17 14600 16889 54788 21411 6.33_151.1 74625 26438 54578 21839 93314 15507 4573 2793 2565 6.34_595.19 17454 22301 15083 11118 6.35_332.07 7649 7855 27835 19681 6.36_316.1 19124 18136 68635 22916 6.37_441.33 21140 5929 19409 23593 6.38_233.11 8187 24423 2101608 909392 6.38_60.06 4458 6006 7851 11867 5962 5385 39863 45001 6.39_294.12 6471 5548 22751 8303 6.39_173.14 6355 8210 22465 27467 6.4_276.11 49418 17523 88577 44048 6.4_384.77 5932 4088 9931 9439 6.41_243.18 2049 29287 6169 4705 17474 23337 3774 22513 34766 6.42_369.09 4932 6174 13943 4782 3202 2058 4203 6.43_485.36 56629 12671 9117 20299 34114 5017 29552 50464 6.45_298.1 7342 18475 3945 9185 7851 14563 9048 6.45_311.15 9390 2847 8040 32314 10601 6.47_643.38 3239 6272 2258 7077 6495 2447 2385 6.49_191.13 43528 8187 32848 33739 6.5_207.12 34105 6909 6100 11145 6301 3601 60934 80595 6.52_171.11 249616 6576 2014 25812 9397 95858 35726 6.54_253.13 5656 8747 3337 11429 5912 3321 6930 8617 6.54_270.15 4858 7581 3260 10403 5293 2467 6815 7818 6.54_275.11 17962 24395 7823 27340 10717 4457 19760 29818 6.56_367.09 82704 212930 220744 192998 193592 192965 64715 104298 6.57_157.1 235589 20620 6680 592971 4743 512791 778981 6.57_110.08 5945 14408 12574 18406 6.59_563.19 65905 85855 5139 2391 15856 19035 10522 7165 20626 6.6_282.12 55867 38008 3043 2386 11690 15131 8151 2708 6.6_430.28 7785 2111 17071 10879 6.6_298.1 61034 18475 3945 14563 9048 6.61_340.08 8680 8235 7046 11012 7480 3032 4072 6.62_234.16 19725 3438 2289 19107 19832 6.62_164.13 4937 3254 4505 3779 3514 2960 68831 6.63_169.1 2933 5879 3708 8774 5718 6.66_145.13 8003 19631 6539 78708 65948 6.67_181.11 7467 6438 20000 4834 22064 4033 3242 2336 6.7_239.15 13506 21150 3040 2055 6561 3032 6823 2285 6.7_224.09 46666 28001 47263 24877 6.7_185.09 18025 3521 11505 2497 32788 25469 6.72_150.11 10948 9704 37091 10952 4258 20799 20216 6.72_172.1 3123 3224 11256 4946 2176 2314 2885 6.73_125.07 69632 11745 5688 3504 81179 3528 6.73_146.12 2069 18937 2481 18451 26579 6.75_225.09 127174 6783 3769 339334 42529 6.75_361.24 11965 14635 6994 8974 4490 3209 6.76_208.11 3460 12030 11889 21571 6.76_230.19 7075 7715 65606 103148 72109 363169 549223 6.77_254.16 5203 4530 4248 4670 4062 3104 8621 6396 6.77_229.12 3244 8949 4531 314631 134436 6.79_360.2 7547 53974 31237 67830 51650 18169 9802 9381 6.79_203.1 263998 4775 2751 2614 505450 97368 6.8_447.13 17074 32325 14215 9110 6775 6150 6.81_88.08 15645 21732 8373 21710 18235 9582 52365 35833 6.82_114.06 73549 5199 2699 2871 2817 142708 69154 6.83_117.11 3114 17938 16724 17534 17533 16123 9038 8748 6.83_216.17 7855 10203 68318 41704 6.84_340.08 7825 8235 7046 7572 7480 3032 3452 6.84_153.09 5979 5140 5775 5590 6085 2853 3231 6.84_268.01 5409 8406 6573 13018 6.84_205.1 6813 2169 14774 3899 20780 5780 6.84_60.06 2237 3877 3423 4143 3439 3333 6332 6206 6.85_316.18 12137 6960 14937 10045 3987 2514 6.85_721.51 4427 3924 3851 3677 3466 3640 4834 6.86_219.1 100110 2582 199539 91891 6.86_338.06 8740 6937 12127 10452 4882 5220 7366 6.86_143.08 147161 28424 160664 8074 169367 89901 6.86_250.99 41248 72847 12879 49121 39501 18698 77802 114127 6.9_265.11 16409753 5361220 953449 587346 440412 318195 280532 72775 71237 6.91_139.09 9401839 58773 767391 532429 371402 267042 198547 86502 80192 6.95_122.07 877750 626357 96550 63112 44080 32023 29602 52274 27492 6.95_166.09 2477 7260 11890 222872 13208 8776 5322 17105 137032 6.97_120.08 2520 36931 2543 13566 6.97_123.07 62710 43684 8096 5376 3770 2858 2593 3385 2513 6.99_131.12 32375 25953 24694 128814 354734 86678 141363 245723 6.99_267.11 945646 34441 49120 30375 23328 17909 15498 8740 6513 6.99_144.05 332483 42211 32408 20502 15257 11127 10823 17555 8923 7_573.15 4835 10380 5782 11210 11005 14794 7.08_247.06 5772 5917 8869 4828 2167 7.08_208.01 25074 16952 3080 3029 7.08_206.89 58480 11023 2049 6978 6272 57605 61531 7.08_169.1 9174 21787 42584 14369 6756 20908 7.09_124.92 14662 5850 4802 14518 15909 7.1_290.85 104119 10518 6332 105000 111904 7.19_367.09 43378 79993 69818 75761 89305 7.26_237.09 2167 5756 15057 9840 7.27_123.09 11288 19681 4717 2126 12177 6020 7.27_215.1 9523 12290 1482373 674538 7.38_401.11 16473 11894 21333 21227 7.39_160.1 12900 534414 71893 14821 7.42_251.14 3631 7040 61145 56928 7.47_269.12 2459 2568 20764 17912 7.47_140.09 725669 136638 57557 39753 12924 21748 16179 5310 16387 7.47_267.11 97504 18172 11973 7972 5943 5194 4019 2443 5537 7.48_259.13 13981 13295 12360 8742 7.55_369.21 628949 78365 6565 4608 36078 55045 24073 5877 3365 7.57_315.11 8044 53539 6013 10191 7.59_448.13 2442 8130 5784 4413 3874 2703 7.61_119.09 8713 60481 2306 25180 10582 7.61_187.11 129867 267003 247288 126518 7.62_219.08 6556 6112 18197 4216 22900 20857 7.62_257.04 7250 4273 37585 27337 7.62_331.09 11202 22497 33103 7812 7.62_241.06 2135 9597 21185 4361 11147 16195 7.63_181.1 9343 2028 31263 11342 7.63_122.07 151800 27439 23412 17016 12447 8691 7400 2493 3791 7.64_72.08 46895 315960 140879 51529 7.66_447.13 15863 65363 40847 29651 22159 17887 4059 7.69_195.07 12267 9323 6827 21013 7.69_173.09 5191 23750 8621 21322 57236 7.71_173.08 5191 23750 5367 21322 57236 7.72_140.1 725669 136638 57557 39753 29452 21748 16179 5310 7566 7.8_146.09 3021 6565 17984 4031 6807 3899 7532 4789 7.8_527.17 53391 53506 29582 13608 6519 3661 7.84_498.9 2372 32659 6677 3423 6407 6337 3876 35450 31426 7.86_203.05 4097 50278 12001 3350 2408 55103 23611 7.89_144.05 40179 3729 5500 3045 3331 2533 2138 7.9_185.09 4415 52855 2979 9894 8160 7.91_267.12 96948 16068 8323 5360 4631 3921 3095 3210 7.99_217.13 438066 2110 2390 80299 33173 8.01_225.08 24376 51420 18659 6358 28640 51694 8.01_203.1 11336 27752 9163 2338 17147 29128 8.07_150.08 17115 81829 16357 48470 22005 8.14_140.1 370751 31937 30218 12198 19940 14066 10750 5738 4848 8.16_90.06 7113 37447 14860 2665 2585 12193 9987 8.24_272.16 2077 36831 15748 10630 50355 35724 8.25_527.17 53391 5632 2475 4605 2608 8.3_175.11 36520 93616 71536 103391 8.3_197.09 30667 65409 45931 49619 8.3_213.06 7890 7541 10067 13461 8.31_209.1 2052304 304886 40023 9895 74919 8115 2701 17894 16451 8.37_120.06 30352 13938 3291 41354 19854 8.47_224.12 2735 8345 3702 2435 15612 11655 8.65_152.09 24427 13677 3248 3762 34691 47274 8.72_266.12 189040 107726 12468 5910 5365 4350 3764 117961 26489 8.75_201.09 12800 233625 4887 509739 8.79_162.08 2128 101350 44194 13121 8990 154077 41967 8.8_180.09 35983 17522 5871 3822 50775 16645 8.8_365.11 42744 6990 33660 20191 8.86_188.18 41968 87223 467736 499732 8.96_140.1 98965 22767 14938 9025 6084 4784 3455 2918 9.01_508.31 48442 7434 5755 9542 9.02_252.11 132682 5878 122946 49916 9.06_363.14 5262 14318 15592 40526 23046 9.07_103.12 5581 36959 51554 37202 9.09_217.08 8990 22145 77579 17711 9.11_219.1 754183 64755 900901 343844 9.15_211.64 125305 15043 6932 2724 9.15_422.28 79595 19020 4182 4392 3313 2969 9.16_114.06 2941 5384 3374 3036 2267 2169 2269 5382 3497 9.17_270.11 33886 25307 263747 235480 9.25_98.98 9806 38434 29385 8607 9.3_680.99 15002 2440 22208 10875 5077 3469 3155 11318 9.31_250.99 37588 13802 17788 6254 5453 4983 4947 10048 20887 9.33_355.93 9608 15706 4784 2427 10654 11542 9.33_347.15 17588 5631 21618 10220 9.33_367.1 16695 3274 59631 63038 50124 41112 38471 3858 12323 9.35_254.07 7529 421791 31594 311110 392505 9.35_176.06 19810 933902 38730 6164 2741 2354 1709566 1611754 9.36_353.94 19703 34173 10398 4707 3793 3518 3163 11018 26249 9.38_208.11 55586 4086 7834 4351 9.38_620.94 40021 27636 32768 5021 14666 40990 9.4_564.89 9260 8826 7349 5800 9.4_439.26 375660 10766 3404 4085 16427 3542 9.44_622.94 16915 11705 14901 2363 6592 12186 9.44_342.14 2778 59686 46627 2039 19543 6144 9.45_665.84 10559 34585 29826 29100 9.45_679 34934 13089 53511 24772 11744 7827 6538 11504 23834 9.46_667.84 9667 31446 26932 25841 9.46_725.89 5336 7100 8284 7155 9.47_723.89 6014 7399 9887 8501 9.5_278.07 179382 7416 79872 231962 9.5_291.12 10685 424409 11848 418315 79736 9.51_259.09 6832 17399 18499 6042 9.58_990.9 15022 7152 9691 2118 7916 12106 9.6_181.63 110163 23272 27994 14109 8268 4711 2715 9.6_611.23 74055 6169 24351 31249 19444 9281 4494 9.6_181.13 502664 105762 126265 66540 36670 19995 12123 2169 3388 9.61_361.25 685855 107860 134547 81700 52477 38988 22568 2380 3251 9.62_272.16 14542 4696 5336 5173 5806 4951 4396 11307 7655 9.68_371.25 20758 6902 7222 5031 2236 9.73_122.07 94601 4417 5991 6024 4154 3555 3187 9.75_401.27 16909 8126 5056 4599 3047 9.76_367.1 26548 5066 42654 29293 35013 33413 30801 6721 9791 9.81_289.19 14804 6738 8623 8934 5803 3778 2731 9.84_140.1 88432 11082 11938 7953 6084 4784 3710 2475 9.87_447.13 50430 11258 8108 4999 3064 2375 9.93_262.18 16292 6535 6479 5257 3269 2524 9.98_203 3574 10296 3953 2847 3286 2762 3735 4718 5586 9.99_296.2 16918 6316 6358 4420 3125 2700 9.99_110.01 26856 51850 26422 26683 28036 29032 29493 24297 28349 9.99_112.01 4385 7837 4337 4221 4875 4701 4719 3934 4338 10.01_114.07 3239 4803 4265 3644 2317 2286 2222 4251 3886 10.42_922.01 34968 56615 144035 1132006 121538 27135 24196 3680 26460 10.56_353.94 2535 31902 4894 3611 5681 6307 9802 41451 30054 10.6_121.05 7634 13114 29400 307438 69841 8650 10628 5757 12934 11.23_922.01 34701 542779 110261 24764 8257 27135 24196 4437 26460 12.81_721.51 2842 5093 4778 4795 5042 5204 4727 5759 5562 13.93_923.01 6697 21839 22242 50266 26076 5721 5259 4289 14.4_922.01 43373 57195 35822 104308 1153114 27135 24196 2788 19648 14.51_924.01 2156 3489 52625 19090 15.15_922.01 44723 433571 72976 38607 38300 27135 24196 3422 17896 15.94_922.01 56849 404576 58246 106519 31608 25863 23058 2607 17365 16.48_923.01 12935 164206 13245 37434 11955 5408 4836 3793 16.55_922.01 62842 535892 41039 814540 1723352 24969 23058 2183 16722 16.61_923.01 15507 164206 7858 158847 331417 5408 4836 3793 16.78_121.05 23804 42785 22499 77877 78395 21017 1776532 14099 11225 16.84_924.01 2573 6018 5799 13515 6735 21798 MS_METABOLITE_DATA_END #METABOLITES METABOLITES_START metabolite_name Retention Time Quantified m/z KEGG ID PubChem ID 1.26_163.08 1.256 163.0780 1.29_146.06 1.290 146.0591 1.26_167.03 1.261 167.0301 9.62_355.11 9.622 355.1145 7.14_132.1 7.144 132.1021 6.09_154.1 6.086 154.0969 1.84_206.14 1.841 206.1374 8.85_148.06 8.847 148.0604 8.4_147.07 8.399 147.0741 6.82_209.09 6.816 209.0946 1.42_170.08 1.422 170.0791 8.15_112.04 8.152 112.0371 7.63_118.09 7.632 118.0863 7.47_139.1 7.469 139.0960 8.06_139.1 8.058 139.0977 8.05_265.11 8.054 265.1117 7.3_265.11 7.296 265.1118 1.42_144.06 1.416 144.0601 1.05_688.2 1.049 688.1969 1.05_750.52 1.052 750.5209 1.05_684.2 1.052 684.2025 1.05_1073.31 1.054 1073.3064 1.05_1074.31 1.054 1074.3051 1.06_998.29 1.056 998.2876 1.06_1148.32 1.057 1148.3236 1.06_792.61 1.058 792.6055 1.06_1000.29 1.059 1000.2865 1.06_1194.82 1.060 1194.8186 1.06_1002.28 1.060 1002.2789 1.06_610.18 1.060 610.1842 1.06_924.27 1.060 924.2689 1.06_999.29 1.060 999.2881 1.06_925.27 1.062 925.2671 1.06_536.17 1.063 536.1656 1.06_722.52 1.063 722.5168 1.06_721.51 1.064 721.5065 1.06_850.25 1.065 850.2509 1.07_776.23 1.070 776.2319 1.07_702.21 1.071 702.2132 1.07_531.41 1.073 531.4051 1.08_665.45 1.076 665.4537 1.08_419.31 1.079 419.3140 1.08_628.19 1.081 628.1946 1.08_686.45 1.082 686.4485 1.08_637.31 1.084 637.3077 1.08_654.33 1.085 654.3336 1.08_680.48 1.085 680.4797 1.09_433.33 1.090 433.3342 1.09_149.02 1.091 149.0241 1.1_548.42 1.099 548.4162 1.1_607.39 1.103 607.3884 1.1_519.4 1.103 519.4026 1.11_504.39 1.107 504.3864 1.11_447.28 1.111 447.2797 1.11_323.15 1.111 323.1472 1.11_446.3 1.112 446.3039 1.11_929.62 1.113 929.6175 1.11_562.39 1.113 562.3910 1.11_636.46 1.113 636.4633 1.12_329.19 1.118 329.1939 1.12_592.43 1.118 592.4327 1.12_606.46 1.119 606.4555 1.12_457.28 1.119 457.2815 1.12_460.36 1.120 460.3567 1.12_322.2 1.120 322.2018 1.12_422.25 1.122 422.2537 1.12_427.18 1.122 427.1776 1.12_434.28 1.123 434.2754 1.12_301.16 1.123 301.1621 1.12_346.29 1.123 346.2889 1.13_268.17 1.125 268.1748 1.13_518.3 1.125 518.2990 1.13_318.19 1.126 318.1897 1.13_297.17 1.126 297.1700 1.13_358.2 1.128 358.2033 1.13_371.21 1.128 371.2070 1.13_372.23 1.128 372.2312 1.13_418.24 1.130 418.2440 1.13_504.29 1.131 504.2859 1.13_328.16 1.132 328.1571 1.13_399.25 1.132 399.2508 1.13_334.21 1.133 334.2116 1.13_446.28 1.133 446.2767 1.13_506.3 1.133 506.3032 1.13_393.22 1.133 393.2180 1.13_593.34 1.134 593.3375 1.13_592.34 1.134 592.3374 1.13_421.24 1.134 421.2408 1.14_302.18 1.136 302.1758 1.14_420.32 1.136 420.3208 1.14_606.36 1.137 606.3566 1.14_421.32 1.137 421.3229 1.14_359.2 1.137 359.2043 1.14_492.28 1.137 492.2832 1.14_701.41 1.140 701.4116 1.14_411.2 1.141 411.2013 1.14_297.08 1.141 297.0824 1.14_563.32 1.143 563.3156 1.14_306.18 1.143 306.1845 1.14_357.19 1.144 357.1913 1.15_369.19 1.145 369.1914 1.15_327.2 1.146 327.1965 1.15_347.31 1.146 347.3106 1.15_390.24 1.147 390.2408 1.15_245.15 1.148 245.1519 1.15_259.14 1.148 259.1406 1.15_291.15 1.149 291.1517 1.15_520.41 1.150 520.4137 1.15_385.22 1.150 385.2249 1.15_450.37 1.152 450.3694 1.15_410.26 1.152 410.2558 1.15_1000.78 1.153 1000.7840 1.15_315.18 1.154 315.1825 1.15_323.21 1.154 323.2081 1.15_476.39 1.155 476.3891 1.16_556.32 1.155 556.3156 1.16_386.25 1.155 386.2498 1.16_448.35 1.155 448.3529 1.16_376.21 1.156 376.2079 1.16_332.2 1.156 332.2049 1.16_227.13 1.158 227.1257 1.16_490.36 1.158 490.3619 1.16_319.28 1.158 319.2803 1.16_600.39 1.159 600.3869 1.16_408.36 1.160 408.3597 1.16_255.13 1.161 255.1254 1.16_350.32 1.162 350.3221 1.16_436.26 1.164 436.2615 1.17_405.3 1.165 405.3035 1.17_565.44 1.165 565.4387 1.17_452.39 1.166 452.3891 1.17_392.24 1.168 392.2360 1.17_564.44 1.169 564.4358 1.17_423.2 1.170 423.2008 1.17_308.15 1.170 308.1535 1.17_441.3 1.170 441.3012 1.17_327.26 1.171 327.2647 1.17_532.38 1.172 532.3819 1.17_541.36 1.172 541.3600 1.17_287.15 1.173 287.1534 1.17_226.19 1.174 226.1872 1.17_335.23 1.174 335.2329 1.17_494.4 1.174 494.4018 1.18_450.27 1.175 450.2714 1.18_462.33 1.175 462.3340 1.18_439.3 1.175 439.3047 1.18_351.26 1.176 351.2580 1.18_363.3 1.176 363.3018 1.18_369.29 1.176 369.2934 1.18_586.34 1.177 586.3396 1.18_285.17 1.177 285.1658 1.18_492.39 1.177 492.3853 1.18_578.41 1.178 578.4122 1.18_758.49 1.178 758.4866 1.18_636.32 1.180 636.3171 1.18_107.08 1.180 107.0826 1.18_609.46 1.181 609.4604 1.18_404.22 1.181 404.2229 1.18_333.29 1.181 333.2857 1.18_608.46 1.182 608.4624 1.18_652.48 1.182 652.4842 1.18_261.13 1.183 261.1285 1.18_443.27 1.184 443.2711 1.19_377.31 1.186 377.3125 1.19_343.18 1.186 343.1833 1.19_334.3 1.186 334.2954 1.19_395.35 1.186 395.3500 1.19_653.49 1.187 653.4896 1.19_209.12 1.187 209.1185 1.19_332.28 1.187 332.2754 1.19_438.37 1.187 438.3720 1.19_192.18 1.187 192.1760 1.19_149.13 1.188 149.1291 1.19_926.53 1.188 926.5320 1.19_499.32 1.188 499.3245 1.19_580.43 1.189 580.4334 1.19_660.4 1.189 660.3993 1.19_349.26 1.189 349.2569 1.19_191.18 1.189 191.1760 1.19_656.49 1.191 656.4941 1.19_551.28 1.191 551.2787 1.19_582.44 1.191 582.4437 1.19_135.11 1.192 135.1127 1.19_376.3 1.192 376.3046 1.19_424.36 1.192 424.3559 1.19_466.38 1.192 466.3753 1.19_394.34 1.192 394.3439 1.19_153.12 1.193 153.1231 1.19_276.21 1.193 276.2094 1.19_594.42 1.194 594.4164 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1.916 239.1474 1.92_327.2 1.916 327.2013 1.92_372.23 1.922 372.2334 1.92_305.16 1.922 305.1577 1.93_155.08 1.933 155.0809 1.94_164.09 1.935 164.0910 1.95_114.06 1.951 114.0592 1.95_323.17 1.953 323.1700 1.96_329.12 1.956 329.1234 1.96_128.07 1.961 128.0702 1.96_208.1 1.961 208.0975 1.96_146.06 1.965 146.0639 1.97_228.27 1.968 228.2673 1.97_219.12 1.968 219.1198 1.99_344.23 1.988 344.2273 2_189.05 1.998 189.0513 2_416.23 1.999 416.2338 2.02_258.28 2.018 258.2787 2.03_388.25 2.027 388.2540 2.04_188.09 2.036 188.0926 2.05_390.26 2.055 390.2589 2.06_681.45 2.063 681.4501 2.07_472.28 2.071 472.2775 2.07_384.22 2.073 384.2224 2.08_367.19 2.075 367.1910 2.08_432.28 2.080 432.2799 2.09_190.1 2.087 190.0958 2.09_242.28 2.090 242.2833 2.09_677.48 2.090 677.4780 2.1_371.23 2.099 371.2290 2.11_725.47 2.108 725.4736 2.11_89.07 2.112 89.0654 2.12_228.08 2.118 228.0846 2.12_724.47 2.123 724.4676 2.13_279.17 2.134 279.1698 2.13_159.11 2.135 159.1123 2.14_340.2 2.138 340.1982 2.14_476.31 2.139 476.3058 2.14_234.17 2.143 234.1695 2.15_231.25 2.154 231.2490 2.16_428.25 2.159 428.2509 2.16_114.07 2.159 114.0667 2.16_295.15 2.162 295.1517 2.16_473.28 2.164 473.2824 2.17_400.38 2.170 400.3773 2.18_189.1 2.178 189.0999 2.18_560.33 2.183 560.3279 2.18_173.13 2.183 173.1273 2.2_521.34 2.197 521.3350 2.21_285.23 2.207 285.2273 2.21_520.33 2.209 520.3320 2.21_371.23 2.210 371.2296 2.24_516.3 2.236 516.3018 2.25_477.31 2.249 477.3086 2.26_86.06 2.258 86.0605 2.26_604.35 2.261 604.3546 2.27_228.19 2.269 228.1877 2.27_137.07 2.272 137.0709 2.28_174.11 2.275 174.1116 2.28_156.08 2.276 156.0838 2.28_812.52 2.281 812.5194 2.29_131.08 2.290 131.0812 2.29_115.06 2.290 115.0583 2.29_227.17 2.290 227.1721 2.32_174.14 2.324 174.1434 2.33_208.15 2.328 208.1525 2.33_178.07 2.330 178.0742 2.33_564.36 2.334 564.3583 2.34_629.33 2.340 629.3290 2.34_279.17 2.344 279.1733 2.36_443.24 2.356 443.2375 2.37_437.29 2.371 437.2886 2.37_459.3 2.371 459.3016 2.38_699.41 2.378 699.4069 2.38_648.38 2.380 648.3799 2.38_155.08 2.383 155.0812 2.4_369.38 2.397 369.3840 2.41_281.16 2.411 281.1616 2.42_565.36 2.418 565.3615 2.42_221.13 2.422 221.1290 2.42_200.23 2.423 200.2349 2.44_562.89 2.437 562.8892 2.45_209.1 2.448 209.1046 2.46_114.06 2.465 114.0579 2.47_163.09 2.467 163.0886 2.47_316.32 2.470 316.3205 2.49_160.17 2.488 160.1689 2.53_166.09 2.527 166.0931 2.53_696.93 2.534 696.9258 2.54_249.15 2.544 249.1507 2.56_126.07 2.556 126.0671 2.56_230.25 2.560 230.2475 2.56_217.1 2.565 217.0981 2.57_481.32 2.574 481.3159 2.58_652.41 2.580 652.4105 2.58_199.11 2.581 199.1079 2.58_692.41 2.584 692.4062 2.59_141.07 2.593 141.0658 2.6_132.07 2.595 132.0668 2.61_185.09 2.611 185.0915 2.61_346.2 2.613 346.1982 2.62_310.13 2.616 310.1268 2.62_288.14 2.622 288.1443 2.62_430.39 2.623 430.3881 2.62_288.29 2.624 288.2892 2.62_375.21 2.624 375.2121 2.63_302.23 2.630 302.2296 2.64_270.13 2.639 270.1335 2.66_230.14 2.656 230.1379 2.66_169.1 2.664 169.0967 2.68_180.1 2.682 180.1022 2.68_232.12 2.684 232.1182 2.68_289.29 2.685 289.2924 2.69_211.11 2.688 211.1078 2.71_246.14 2.705 246.1362 2.71_223.12 2.710 223.1151 2.71_736.43 2.711 736.4318 2.71_503.33 2.713 503.3287 2.71_155.15 2.714 155.1536 2.72_533.31 2.718 533.3078 2.72_139.08 2.721 139.0836 2.72_175.1 2.722 175.1038 2.73_696.44 2.731 696.4370 2.73_279.17 2.732 279.1729 2.73_218.21 2.732 218.2105 2.77_142.09 2.766 142.0856 2.79_297.1 2.786 297.1016 2.79_216.12 2.789 216.1208 2.81_235.11 2.808 235.1128 2.82_310.14 2.815 310.1370 2.84_780.46 2.843 780.4569 2.89_298.1 2.888 298.0973 2.89_467.31 2.890 467.3113 2.91_288.29 2.907 288.2887 2.91_251.11 2.911 251.1057 2.91_244.26 2.913 244.2615 2.92_329.11 2.917 329.1135 2.92_148.09 2.925 148.0856 2.93_277.24 2.933 277.2376 2.94_230.14 2.938 230.1400 2.94_132.07 2.940 132.0654 2.97_183.11 2.970 183.1104 2.98_231.14 2.982 231.1447 3.02_264.21 3.018 264.2062 3.03_185.1 3.025 185.0965 3.05_360.22 3.049 360.2202 3.05_263.2 3.052 263.2001 3.08_159.09 3.079 159.0903 3.08_140.08 3.084 140.0812 3.09_316.21 3.092 316.2103 3.11_172.1 3.114 172.0961 3.13_244.16 3.128 244.1639 3.18_562.89 3.179 562.8893 3.22_474.23 3.217 474.2343 3.22_166.09 3.220 166.0939 3.25_245.15 3.249 245.1508 3.25_152.07 3.254 152.0730 3.26_340.26 3.259 340.2588 3.29_230.25 3.288 230.2472 3.29_188.2 3.292 188.2003 3.3_280.12 3.302 280.1181 3.32_182.1 3.322 182.1007 3.36_214.11 3.360 214.1058 3.48_272.19 3.475 272.1859 3.59_923.01 3.587 923.0125 3.59_283.16 3.591 283.1643 3.6_187.14 3.599 187.1426 3.62_280.12 3.618 280.1177 3.63_128.07 3.630 128.0705 3.64_139.12 3.640 139.1201 3.65_162.1 3.647 162.1022 3.75_138.09 3.755 138.0942 3.81_128.14 3.810 128.1431 3.97_190.14 3.972 190.1427 4.1_156.14 4.104 156.1377 4.14_144.14 4.142 144.1377 4.15_144.25 4.150 144.2483 4.15_145.14 4.151 145.1412 4.16_287.27 4.157 287.2692 4.16_537.25 4.159 537.2497 4.16_806.58 4.164 806.5834 4.17_394.12 4.174 394.1189 4.18_924.01 4.181 924.0140 4.19_452.17 4.189 452.1721 4.23_125.11 4.232 125.1055 4.26_208.15 4.261 208.1537 4.35_599.39 4.349 599.3886 4.38_319.18 4.385 319.1804 4.44_169.1 4.444 169.0962 4.48_402.21 4.476 402.2131 4.49_114.06 4.489 114.0568 4.53_204.09 4.530 204.0869 4.55_186.08 4.555 186.0759 4.61_258.11 4.605 258.1085 4.64_166.09 4.641 166.0925 4.65_422.23 4.653 422.2282 4.67_480.28 4.666 480.2816 4.67_444.21 4.670 444.2114 4.68_509.3 4.679 509.2968 4.68_421.21 4.681 421.2117 4.68_98.98 4.683 98.9846 4.68_155.05 4.684 155.0472 4.71_114.13 4.707 114.1275 4.72_211.11 4.718 211.1109 4.75_152.07 4.749 152.0712 4.76_267.14 4.756 267.1443 4.81_139.09 4.810 139.0904 4.82_253.12 4.823 253.1188 4.83_258.28 4.826 258.2786 4.84_188.13 4.842 188.1273 4.85_139.1 4.852 139.0976 4.86_112.09 4.858 112.0947 4.87_471.16 4.872 471.1564 4.87_361.07 4.874 361.0718 4.9_466.18 4.898 466.1759 4.9_270.22 4.899 270.2169 4.9_563.43 4.901 563.4274 4.9_449.15 4.902 449.1496 4.91_419.13 4.906 419.1253 4.92_453.34 4.919 453.3434 4.93_230.25 4.925 230.2474 4.94_111.09 4.939 111.0917 4.95_475.32 4.954 475.3247 4.96_136.06 4.965 136.0624 4.97_511.4 4.974 511.3959 4.98_162.11 4.976 162.1125 5_153.1 5.001 153.1006 5.03_155.12 5.026 155.1166 5.03_90.06 5.032 90.0555 5.03_132.07 5.033 132.0654 5.06_430.3 5.056 430.2962 5.09_174.15 5.089 174.1483 5.09_500.19 5.090 500.1929 5.1_193.16 5.099 193.1595 5.1_116.11 5.103 116.1068 5.11_192.16 5.108 192.1587 5.11_399.36 5.112 399.3576 5.12_56.05 5.125 56.0506 5.12_166.08 5.125 166.0805 5.13_443.12 5.127 443.1250 5.13_347.06 5.131 347.0559 5.13_255.07 5.131 255.0663 5.13_464.18 5.132 464.1787 5.14_118.12 5.135 118.1214 5.15_97.08 5.152 97.0763 5.16_224.12 5.164 224.1199 5.17_485.22 5.171 485.2188 5.17_118.22 5.174 118.2223 5.18_119.13 5.176 119.1257 5.18_426.16 5.180 426.1556 5.18_114.06 5.183 114.0641 5.19_405.11 5.186 405.1092 5.19_923.01 5.190 923.0124 5.21_429.38 5.205 429.3798 5.21_371.33 5.211 371.3264 5.22_268.1 5.219 268.1049 5.22_922.36 5.222 922.3579 5.23_348.27 5.232 348.2749 5.23_518.32 5.234 518.3169 5.24_160.11 5.241 160.1077 5.24_187.08 5.243 187.0842 5.24_187.09 5.243 187.0860 5.24_137.05 5.244 137.0457 5.25_159.03 5.252 159.0273 5.26_175.09 5.256 175.0861 5.27_195.1 5.271 195.1035 5.3_100.11 5.304 100.1121 5.31_236.15 5.306 236.1503 5.31_562.34 5.311 562.3428 5.32_55.06 5.325 55.0551 5.33_762.56 5.327 762.5579 5.33_245.1 5.327 245.0969 5.33_125.07 5.329 125.0750 5.33_83.09 5.330 83.0857 5.34_350.09 5.335 350.0918 5.34_449.2 5.335 449.1966 5.35_437.16 5.350 437.1605 5.35_408.15 5.352 408.1452 5.36_134.12 5.359 134.1169 5.36_171.15 5.361 171.1481 5.38_141.1 5.380 141.1016 5.39_606.37 5.394 606.3690 5.4_650.4 5.400 650.4048 5.4_224.17 5.402 224.1743 5.44_628.38 5.435 628.3824 5.44_293.2 5.439 293.1961 5.45_104.11 5.445 104.1071 5.45_584.36 5.448 584.3576 5.45_303.2 5.448 303.1962 5.47_211.15 5.468 211.1457 5.47_672.41 5.471 672.4091 5.48_738.45 5.481 738.4487 5.49_624.48 5.485 624.4779 5.49_566.43 5.490 566.4269 5.49_302.2 5.491 302.1960 5.49_182.09 5.493 182.0926 5.49_610.23 5.493 610.2290 5.51_448.12 5.512 448.1161 5.52_164.06 5.521 164.0566 5.53_123.09 5.533 123.0911 5.54_158.15 5.539 158.1535 5.55_210.16 5.547 210.1590 5.56_466.19 5.558 466.1867 5.56_110.07 5.563 110.0668 5.58_140.08 5.579 140.0830 5.58_565.32 5.585 565.3153 5.59_178.09 5.593 178.0888 5.61_258.17 5.608 258.1695 5.62_209.13 5.622 209.1302 5.63_679.5 5.629 679.5029 5.65_449.14 5.646 449.1353 5.67_202.18 5.668 202.1798 5.67_198.11 5.671 198.1141 5.67_737.56 5.674 737.5642 5.68_165.11 5.681 165.1125 5.69_510.21 5.694 510.2137 5.7_679 5.702 678.9952 5.71_142.11 5.713 142.1052 5.72_251.15 5.721 251.1479 5.74_197.13 5.739 197.1284 5.78_585.37 5.781 585.3745 5.79_109.08 5.790 109.0761 5.81_224.13 5.812 224.1343 5.81_293.19 5.813 293.1909 5.81_203.08 5.815 203.0849 5.87_155.08 5.873 155.0830 5.89_205.1 5.887 205.0966 5.91_130.1 5.915 130.0976 5.92_185.16 5.924 185.1642 5.93_534.31 5.930 534.3119 5.93_578.34 5.932 578.3394 5.95_114.07 5.952 114.0676 5.95_490.29 5.953 490.2859 5.95_128.09 5.953 128.0897 5.97_207.12 5.971 207.1238 5.98_446.26 5.975 446.2596 6_421.1 5.996 421.1044 6_95.06 6.000 95.0608 6_113.07 6.000 113.0710 6_402.23 6.004 402.2335 6.01_127.08 6.009 127.0843 6.01_435.12 6.011 435.1200 6.01_172.12 6.013 172.1204 6.01_363.16 6.013 363.1624 6.02_170.1 6.016 170.1029 6.02_114.06 6.023 114.0644 6.03_358.21 6.033 358.2074 6.09_314.18 6.086 314.1807 6.09_297.15 6.090 297.1548 6.09_355.21 6.091 355.2078 6.09_319.14 6.093 319.1370 6.1_172.13 6.096 172.1282 6.1_165.11 6.102 165.1066 6.16_140.08 6.156 140.0834 6.17_183.11 6.169 183.1127 6.2_137.11 6.199 137.1070 6.21_491.15 6.205 491.1464 6.23_235.12 6.234 235.1172 6.24_191.08 6.235 191.0814 6.24_258.1 6.243 258.0978 6.26_243.13 6.257 243.1274 6.27_188.13 6.268 188.1281 6.29_381.19 6.286 381.1862 6.31_352.17 6.309 352.1717 6.33_151.1 6.328 151.0975 6.34_595.19 6.344 595.1935 6.35_332.07 6.354 332.0742 6.36_316.1 6.365 316.1005 6.37_441.33 6.374 441.3319 6.38_233.11 6.379 233.1133 6.38_60.06 6.381 60.0596 6.39_294.12 6.394 294.1196 6.39_173.14 6.394 173.1388 6.4_276.11 6.398 276.1082 6.4_384.77 6.399 384.7726 6.41_243.18 6.411 243.1823 6.42_369.09 6.422 369.0873 6.43_485.36 6.431 485.3585 6.45_298.1 6.450 298.0975 6.45_311.15 6.452 311.1455 6.47_643.38 6.472 643.3807 6.49_191.13 6.492 191.1278 6.5_207.12 6.503 207.1194 6.52_171.11 6.525 171.1125 6.54_253.13 6.540 253.1282 6.54_270.15 6.541 270.1545 6.54_275.11 6.542 275.1103 6.56_367.09 6.561 367.0938 6.57_157.1 6.568 157.0970 6.57_110.08 6.571 110.0831 6.59_563.19 6.589 563.1927 6.6_282.12 6.596 282.1152 6.6_430.28 6.597 430.2797 6.6_298.1 6.599 298.0984 6.61_340.08 6.612 340.0825 6.62_234.16 6.618 234.1586 6.62_164.13 6.624 164.1276 6.63_169.1 6.626 169.0969 6.66_145.13 6.663 145.1329 6.67_181.11 6.669 181.1123 6.7_239.15 6.698 239.1455 6.7_224.09 6.700 224.0920 6.7_185.09 6.703 185.0921 6.72_150.11 6.717 150.1120 6.72_172.1 6.721 172.0967 6.73_125.07 6.728 125.0745 6.73_146.12 6.729 146.1174 6.75_225.09 6.747 225.0859 6.75_361.24 6.754 361.2428 6.76_208.11 6.758 208.1089 6.76_230.19 6.760 230.1860 6.77_254.16 6.769 254.1598 6.77_229.12 6.772 229.1184 6.79_360.2 6.787 360.2016 6.79_203.1 6.793 203.1016 6.8_447.13 6.800 447.1313 6.81_88.08 6.814 88.0761 6.82_114.06 6.818 114.0595 6.83_117.11 6.825 117.1133 6.83_216.17 6.833 216.1702 6.84_340.08 6.841 340.0829 6.84_153.09 6.842 153.0906 6.84_268.01 6.844 268.0141 6.84_205.1 6.844 205.0990 6.84_60.06 6.844 60.0632 6.85_316.18 6.853 316.1753 6.85_721.51 6.855 721.5063 6.86_219.1 6.856 219.0987 6.86_338.06 6.862 338.0561 6.86_143.08 6.862 143.0812 6.86_250.99 6.864 250.9871 6.9_265.11 6.900 265.1123 6.91_139.09 6.907 139.0943 6.95_122.07 6.950 122.0711 6.95_166.09 6.952 166.0867 6.97_120.08 6.965 120.0808 6.97_123.07 6.975 123.0749 6.99_131.12 6.989 131.1178 6.99_267.11 6.991 267.1131 6.99_144.05 6.992 144.0477 7_573.15 6.997 573.1463 7.08_247.06 7.076 247.0578 7.08_208.01 7.081 208.0132 7.08_206.89 7.082 206.8854 7.08_169.1 7.083 169.0968 7.09_124.92 7.091 124.9226 7.1_290.85 7.099 290.8469 7.19_367.09 7.193 367.0938 7.26_237.09 7.259 237.0855 7.27_123.09 7.269 123.0908 7.27_215.1 7.270 215.1024 7.38_401.11 7.378 401.1142 7.39_160.1 7.392 160.0969 7.42_251.14 7.417 251.1388 7.47_269.12 7.470 269.1160 7.47_140.09 7.470 140.0949 7.47_267.11 7.472 267.1143 7.48_259.13 7.475 259.1288 7.55_369.21 7.550 369.2143 7.57_315.11 7.569 315.1147 7.59_448.13 7.594 448.1337 7.61_119.09 7.610 119.0893 7.61_187.11 7.613 187.1075 7.62_219.08 7.619 219.0801 7.62_257.04 7.620 257.0357 7.62_331.09 7.622 331.0895 7.62_241.06 7.624 241.0617 7.63_181.1 7.628 181.0967 7.63_122.07 7.629 122.0711 7.64_72.08 7.643 72.0816 7.66_447.13 7.656 447.1312 7.69_195.07 7.686 195.0740 7.69_173.09 7.688 173.0878 7.71_173.08 7.712 173.0811 7.72_140.1 7.722 140.0984 7.8_146.09 7.801 146.0881 7.8_527.17 7.803 527.1686 7.84_498.9 7.838 498.9014 7.86_203.05 7.862 203.0524 7.89_144.05 7.892 144.0478 7.9_185.09 7.900 185.0927 7.91_267.12 7.911 267.1151 7.99_217.13 7.989 217.1284 8.01_225.08 8.007 225.0844 8.01_203.1 8.008 203.1019 8.07_150.08 8.066 150.0758 8.14_140.1 8.144 140.1024 8.16_90.06 8.157 90.0556 8.24_272.16 8.237 272.1600 8.25_527.17 8.250 527.1685 8.3_175.11 8.297 175.1068 8.3_197.09 8.297 197.0884 8.3_213.06 8.297 213.0635 8.31_209.1 8.309 209.1031 8.37_120.06 8.373 120.0650 8.47_224.12 8.465 224.1197 8.65_152.09 8.653 152.0915 8.72_266.12 8.720 266.1171 8.75_201.09 8.754 201.0874 8.79_162.08 8.793 162.0763 8.8_180.09 8.795 180.0866 8.8_365.11 8.797 365.1064 8.86_188.18 8.865 188.1755 8.96_140.1 8.960 140.0972 9.01_508.31 9.012 508.3141 9.02_252.11 9.023 252.1089 9.06_363.14 9.062 363.1406 9.07_103.12 9.072 103.1234 9.09_217.08 9.088 217.0828 9.11_219.1 9.107 219.0978 9.15_211.64 9.148 211.6414 9.15_422.28 9.151 422.2764 9.16_114.06 9.158 114.0616 9.17_270.11 9.167 270.1100 9.25_98.98 9.246 98.9846 9.3_680.99 9.302 680.9940 9.31_250.99 9.314 250.9871 9.33_355.93 9.327 355.9337 9.33_347.15 9.329 347.1455 9.33_367.1 9.335 367.0952 9.35_254.07 9.352 254.0671 9.35_176.06 9.353 176.0553 9.36_353.94 9.360 353.9356 9.38_208.11 9.382 208.1052 9.38_620.94 9.384 620.9428 9.4_564.89 9.397 564.8877 9.4_439.26 9.401 439.2562 9.44_622.94 9.438 622.9410 9.44_342.14 9.441 342.1397 9.45_665.84 9.453 665.8381 9.45_679 9.454 678.9959 9.46_667.84 9.459 667.8363 9.46_725.89 9.461 725.8896 9.47_723.89 9.468 723.8916 9.5_278.07 9.501 278.0671 9.5_291.12 9.501 291.1192 9.51_259.09 9.511 259.0929 9.58_990.9 9.579 990.8971 9.6_181.63 9.597 181.6279 9.6_611.23 9.597 611.2262 9.6_181.13 9.603 181.1258 9.61_361.25 9.611 361.2457 9.62_272.16 9.619 272.1605 9.68_371.25 9.679 371.2544 9.73_122.07 9.732 122.0711 9.75_401.27 9.750 401.2656 9.76_367.1 9.758 367.0966 9.81_289.19 9.810 289.1880 9.84_140.1 9.845 140.0962 9.87_447.13 9.871 447.1312 9.93_262.18 9.929 262.1839 9.98_203 9.976 203.0007 9.99_296.2 9.987 296.1974 9.99_110.01 9.990 110.0089 9.99_112.01 9.991 112.0070 10.01_114.07 10.006 114.0656 10.42_922.01 10.420 922.0098 10.56_353.94 10.556 353.9356 10.6_121.05 10.604 121.0509 11.23_922.01 11.234 922.0098 12.81_721.51 12.813 721.5066 13.93_923.01 13.933 923.0126 14.4_922.01 14.399 922.0098 14.51_924.01 14.512 924.0142 15.15_922.01 15.150 922.0098 15.94_922.01 15.938 922.0098 16.48_923.01 16.477 923.0122 16.55_922.01 16.547 922.0098 16.61_923.01 16.606 923.0123 16.78_121.05 16.782 121.0509 16.84_924.01 16.842 924.0144 METABOLITES_END #END