#METABOLOMICS WORKBENCH hormel101_20170623_123453 DATATRACK_ID:1090 STUDY_ID:ST000641 ANALYSIS_ID:AN000973 PROJECT_ID:PR000458 VERSION 1 CREATED_ON June 25, 2017, 4:58 pm #PROJECT PR:PROJECT_TITLE Biomarkers of diabetes risk in children: role of obesity and exercise PR:PROJECT_SUMMARY This proposal addresses a gap in knowledge about biomarkers for insulin PR:PROJECT_SUMMARY resistance and diabetes. It remains unclear why some populations develop PR:PROJECT_SUMMARY diabetes at higher rates than others and whether prevention and treatment PR:PROJECT_SUMMARY strategies should also differ. The main goal of the current study is to PR:PROJECT_SUMMARY determine the impact of body composition and physical activity on biomarkers for PR:PROJECT_SUMMARY insulin resistance in American Indian adolescents. We propose to use a targeted PR:PROJECT_SUMMARY metabolomic approach to measure amino compounds and fatty acids in plasma. We PR:PROJECT_SUMMARY will address these goals by exploring two Specific Aims: 1. To determine the PR:PROJECT_SUMMARY effects of obesity and physical activity on circulating biomarkers for diabetes PR:PROJECT_SUMMARY and metabolic disease risk in American Indian youth. Plasma samples used for PR:PROJECT_SUMMARY measurements of amino compounds and fatty acids will be acquired from boys and PR:PROJECT_SUMMARY girls 11-21 years old classified as, a) obese, low habitual physical activity PR:PROJECT_SUMMARY and low fitness; b) normal weight, low habitual physical activity and low PR:PROJECT_SUMMARY fitness; or, c) normal weight, high habitual physical activity and high fitness. PR:PROJECT_SUMMARY 2. To determine the impact of exercise training on circulating biomarkers for PR:PROJECT_SUMMARY diabetes and metabolic disease risk in obese American Indian youth. The same PR:PROJECT_SUMMARY obese group tested in the cross-sectional comparison in Aim 1 will complete 16 PR:PROJECT_SUMMARY weeks of aerobic exercise training. Plasma samples acquired before and after PR:PROJECT_SUMMARY training will be used to measure amino compounds and fatty acids. The results of PR:PROJECT_SUMMARY this project will provide novel information about the metabolic changes PR:PROJECT_SUMMARY associated with insulin resistance, obesity, and physical activity in young PR:PROJECT_SUMMARY people who are at risk for, but have not yet developed cardiometabolic disease. PR:PROJECT_SUMMARY The study design takes advantage of, and supports the scientific partnership PR:PROJECT_SUMMARY among investigators at the University of Oklahoma Health Sciences Center, PR:PROJECT_SUMMARY Choctaw Nation of Oklahoma, and Mayo Clinic Rochester. This will set the stage PR:PROJECT_SUMMARY for future lifestyle intervention studies to further explore the concepts PR:PROJECT_SUMMARY outlined in this proposal. PR:INSTITUTE Mayo Clinic PR:LAST_NAME Short PR:FIRST_NAME Ke PR:ADDRESS University of Oklahoma Health Sciences Center 1200 Children’s Ave, Suite 4500 PR:ADDRESS Oklahoma City, OK 73104 PR:EMAIL kevin-short@ouhsc.edu PR:PHONE 405-271-8001 #STUDY ST:STUDY_TITLE Targeted Amino Acids in American Indian Adolescents (part II) ST:STUDY_SUMMARY The goal of this study is to determine the effect of physical activity on the ST:STUDY_SUMMARY blood concentrations of several compounds that are proposed to be markers of ST:STUDY_SUMMARY diabetic risk. We will compare results from normal weight and obese American ST:STUDY_SUMMARY Indian adolescents, with high or low habitual physical activity. We will also ST:STUDY_SUMMARY compare the same blood markers in the obese group before and after 4 months of ST:STUDY_SUMMARY exercise to measure the benefit of the program. ST:INSTITUTE Mayo Clinic ST:LAST_NAME Short ST:FIRST_NAME Kevin ST:ADDRESS University of Oklahoma Health Sciences Center 1200 Children’s Ave, Suite 4500 ST:ADDRESS Oklahoma City, OK 73104 ST:EMAIL kevin-short@ouhsc.edu ST:PHONE 405-271-8001 #SUBJECT SU:SUBJECT_TYPE Human SU:SUBJECT_SPECIES Homo sapiens SU:TAXONOMY_ID 9606 #SUBJECT_SAMPLE_FACTORS: SUBJECT(optional)[tab]SAMPLE[tab]FACTORS(NAME:VALUE pairs separated by |)[tab]Additional sample data SUBJECT_SAMPLE_FACTORS 434-001 ms6169-1 date:7/24/2013 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-001 ms6169-2 date:11/26/2013 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-002 ms6169-3 date:7/31/2013 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-002 ms6169-4 date:11/25/2013 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-004 ms6169-5 date:8/16/2013 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-004 ms6169-6 date:12/23/2013 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-005 ms6169-7 date:9/27/2013 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-005 ms6169-8 date:1/31/2014 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-006 ms6169-9 date:10/2/2013 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-006 ms6169-10 date:1/31/2014 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-007 ms6169-11 date:10/4/2013 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-007 ms6169-12 date:2/7/2014 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-008 ms6169-13 date:10/11/2013 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-008 ms6169-14 date:3/17/2014 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-009 ms6169-15 date:10/2/2013 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-010 ms6169-16 date:9/27/2013 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-010 ms6169-17 date:2/21/2014 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-011 ms6169-18 date:10/25/2013 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-011 ms6169-19 date:3/17/2014 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-013 ms6169-20 date:12/23/2014 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-013 ms6169-21 date:4/28/2014 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-014 ms6169-22 date:3/14/2014 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-015 ms6169-23 date:5/16/2014 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-015 ms6169-24 date:9/5/2014 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-016 ms6169-25 date:7/18/2014 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-016 ms6169-26 date:11/25/2014 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-017 ms6169-27 date:10/30/2014 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-018 ms6169-28 date:12/12/2014 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-018 ms6169-29 date:5/8/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-019 ms6169-30 date:2/20/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-019 ms6169-31 date:7/20/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-020 ms6169-32 date:2/20/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-020 ms6169-33 date:7/20/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-021 ms6169-34 date:3/13/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-021 ms6169-35 date:7/21/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-022 ms6169-36 date:3/13/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-022 ms6169-37 date:7/21/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-023 ms6169-38 date:3/27/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-023 ms6169-39 date:8/7/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-024 ms6169-40 date:3/27/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-024 ms6169-41 date:8/4/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-025 ms6169-42 date:3/27/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-025 ms6169-43 date:8/4/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-026 ms6169-44 date:3/16/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-026 ms6169-45 date:8/11/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-027 ms6169-46 date:3/16/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-027 ms6169-47 date:8/11/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-028 ms6169-48 date:5/5/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-029 ms6169-49 date:5/22/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-029 ms6169-50 date:9/25/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-030 ms6169-51 date:6/11/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-030 ms6169-52 date:10/28/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-031 ms6169-53 date:7/14/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-031 ms6169-54 date:11/6/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-032 ms6169-55 date:7/14/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-032 ms6169-56 date:11/6/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-033 ms6169-57 date:6/30/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-033 ms6169-58 date:11/23/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-034 ms6169-59 date:6/30/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-034 ms6169-60 date:11/17/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-038 ms6169-61 date:8/17/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-038 ms6169-62 date:2/9/2016 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-039 ms6169-63 date:8/28/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-039 ms6169-64 date:2/9/2016 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-040 ms6169-65 date:9/1/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-042 ms6169-66 date:10/23/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-042 ms6169-67 date:3/4/2016 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-044 ms6169-68 date:12/18/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-045 ms6169-69 date:12/18/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-047 ms6169-70 date:2/8/2016 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-048 ms6169-71 date:2/8/2016 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-101 ms6169-72 date:8/29/2014 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-101 ms6169-73 date:12/16/2014 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-102 ms6169-74 date:9/18/2014 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-102 ms6169-75 date:1/20/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-106 ms6169-76 date:10/10/2014 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-106 ms6169-77 date:3/4/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-107 ms6169-78 date:11/28/2014 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-107 ms6169-79 date:5/8/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-110 ms6169-80 date:12/4/2014 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-110 ms6169-81 date:4/10/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-111 ms6169-82 date:12/11/2014 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-111 ms6169-83 date:4/30/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-112 ms6169-84 date:1/5/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-112 ms6169-85 date:5/8/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-113 ms6169-86 date:1/5/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-113 ms6169-87 date:5/8/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-115 ms6169-88 date:2/13/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-118 ms6169-89 date:6/8/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-118 ms6169-90 date:10/5/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-120 ms6169-91 date:8/4/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-120 ms6169-92 date:12/29/2016 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-121 ms6169-93 date:8/5/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-121 ms6169-94 date:12/11/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-123 ms6169-95 date:8/18/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-123 ms6169-96 date:1/15/2016 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-125 ms6169-97 date:8/21/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-128 ms6169-98 date:12/8/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-130 ms6169-99 date:12/29/2016 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-131 ms6169-100 date:12/29/2016 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=F SUBJECT_SAMPLE_FACTORS 434-132 ms6169-101 date:1/5/2016 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program gender=M SUBJECT_SAMPLE_FACTORS 434-301 ms6169-102 date:8/4/2015 | time:baseline | group:normal weight reference group adolescents gender=M SUBJECT_SAMPLE_FACTORS 434-302 ms6169-103 date:8/4/2015 | time:baseline | group:normal weight reference group adolescents gender=M SUBJECT_SAMPLE_FACTORS 434-303 ms6169-104 date:10/19/2015 | time:baseline | group:normal weight reference group adolescents gender=M SUBJECT_SAMPLE_FACTORS 434-304 ms6169-105 date:10/15/2015 | time:baseline | group:normal weight reference group adolescents gender=F SUBJECT_SAMPLE_FACTORS 434-305 ms6169-106 date:12/17/2015 | time:baseline | group:normal weight reference group adolescents gender=M SUBJECT_SAMPLE_FACTORS 434-306 ms6169-107 date:12/17/2015 | time:baseline | group:normal weight reference group adolescents gender=F SUBJECT_SAMPLE_FACTORS 434-307 ms6169-108 date:12/23/2015 | time:baseline | group:normal weight reference group adolescents gender=F SUBJECT_SAMPLE_FACTORS 434-308 ms6169-109 date:1/9/2016 | time:baseline | group:normal weight reference group adolescents gender=M SUBJECT_SAMPLE_FACTORS 11333 ms6169-110 date:6/8/2010 | time:baseline | group:Overweight/Obese adolescents 5 week exercise program gender=M SUBJECT_SAMPLE_FACTORS 11333 ms6169-111 date:7/15/2010 | time:post-training | group:Overweight/Obese adolescents 5 week exercise program gender=M SUBJECT_SAMPLE_FACTORS 11097 ms6169-112 date:5/25/2010 | time:baseline | group:Overweight/Obese adolescents 5 week exercise program gender=M SUBJECT_SAMPLE_FACTORS 11097 ms6169-113 date:6/25/2010 | time:post-training | group:Overweight/Obese adolescents 5 week exercise program gender=M SUBJECT_SAMPLE_FACTORS 11327 ms6169-114 date:6/1/2010 | time:baseline | group:Overweight/Obese adolescents 5 week exercise program gender=M SUBJECT_SAMPLE_FACTORS 11327 ms6169-115 date:7/14/2010 | time:post-training | group:Overweight/Obese adolescents 5 week exercise program gender=M SUBJECT_SAMPLE_FACTORS 11326 ms6169-116 date:6/2/2010 | time:baseline | group:Overweight/Obese adolescents 5 week exercise program gender=M SUBJECT_SAMPLE_FACTORS 11326 ms6169-117 date:7/14/2010 | time:post-training | group:Overweight/Obese adolescents 5 week exercise program gender=M SUBJECT_SAMPLE_FACTORS 11313 ms6169-118 date:6/23/2010 | time:baseline | group:Overweight/Obese adolescents 5 week exercise program gender=F SUBJECT_SAMPLE_FACTORS 11313 ms6169-119 date:8/5/2010 | time:post-training | group:Overweight/Obese adolescents 5 week exercise program gender=F SUBJECT_SAMPLE_FACTORS 11314 ms6169-120 date:6/23/2010 | time:baseline | group:Overweight/Obese adolescents 5 week exercise program gender=F SUBJECT_SAMPLE_FACTORS 11314 ms6169-121 date:8/5/2010 | time:post-training | group:Overweight/Obese adolescents 5 week exercise program gender=F SUBJECT_SAMPLE_FACTORS 11537 ms6169-122 date:8/10/2010 | time:baseline | group:Overweight/Obese adolescents 5 week exercise program gender=F SUBJECT_SAMPLE_FACTORS 11537 ms6169-123 date:9/29/2010 | time:post-training | group:Overweight/Obese adolescents 5 week exercise program gender=F SUBJECT_SAMPLE_FACTORS 11547 ms6169-124 date:8/30/2010 | time:baseline | group:Overweight/Obese adolescents 5 week exercise program gender=M SUBJECT_SAMPLE_FACTORS 11547 ms6169-125 date:9/30/2010 | time:post-training | group:Overweight/Obese adolescents 5 week exercise program gender=M SUBJECT_SAMPLE_FACTORS 11580 ms6169-126 date:12/8/2010 | time:baseline | group:Overweight/Obese adolescents 5 week exercise program gender=F SUBJECT_SAMPLE_FACTORS 11580 ms6169-127 date:2/15/2011 | time:post-training | group:Overweight/Obese adolescents 5 week exercise program gender=F SUBJECT_SAMPLE_FACTORS 11588 ms6169-128 date:1/6/2011 | time:baseline | group:Overweight/Obese adolescents 5 week exercise program gender=F SUBJECT_SAMPLE_FACTORS 11588 ms6169-129 date:2/14/2011 | time:post-training | group:Overweight/Obese adolescents 5 week exercise program gender=F SUBJECT_SAMPLE_FACTORS 11620 ms6169-130 date:2/18/2011 | time:baseline | group:Overweight/Obese adolescents 5 week exercise program gender=M SUBJECT_SAMPLE_FACTORS 11620 ms6169-131 date:4/22/2011 | time:post-training | group:Overweight/Obese adolescents 5 week exercise program gender=M SUBJECT_SAMPLE_FACTORS 11638 ms6169-132 date:5/20/2011 | time:baseline | group:Overweight/Obese adolescents 5 week exercise program gender=M SUBJECT_SAMPLE_FACTORS 11638 ms6169-133 date:7/7/2011 | time:post-training | group:Overweight/Obese adolescents 5 week exercise program gender=M SUBJECT_SAMPLE_FACTORS 11635 ms6169-134 date:5/3/2011 | time:baseline | group:Overweight/Obese adolescents 5 week exercise program gender=F SUBJECT_SAMPLE_FACTORS 11635 ms6169-135 date:6/8/2011 | time:post-training | group:Overweight/Obese adolescents 5 week exercise program gender=F SUBJECT_SAMPLE_FACTORS 11636 ms6169-136 date:5/3/2011 | time:baseline | group:Overweight/Obese adolescents 5 week exercise program gender=M SUBJECT_SAMPLE_FACTORS 11636 ms6169-137 date:6/8/2011 | time:post-training | group:Overweight/Obese adolescents 5 week exercise program gender=M SUBJECT_SAMPLE_FACTORS 11637 ms6169-138 date:5/26/2011 | time:baseline | group:Overweight/Obese adolescents 5 week exercise program gender=M SUBJECT_SAMPLE_FACTORS 11637 ms6169-139 date:8/5/2011 | time:post-training | group:Overweight/Obese adolescents 5 week exercise program gender=M SUBJECT_SAMPLE_FACTORS 11644 ms6169-140 date:7/13/2011 | time:baseline | group:Overweight/Obese adolescents 5 week exercise program gender=M SUBJECT_SAMPLE_FACTORS 11644 ms6169-141 date:8/25/2011 | time:post-training | group:Overweight/Obese adolescents 5 week exercise program gender=M SUBJECT_SAMPLE_FACTORS 11675 ms6169-142 date:6/23/2011 | time:baseline | group:Overweight/Obese adolescents 5 week exercise program gender=M SUBJECT_SAMPLE_FACTORS 11675 ms6169-143 date:8/10/2011 | time:post-training | group:Overweight/Obese adolescents 5 week exercise program gender=M SUBJECT_SAMPLE_FACTORS 11685 ms6169-144 date:7/27/2011 | time:baseline | group:Overweight/Obese adolescents 5 week exercise program gender=M SUBJECT_SAMPLE_FACTORS 11685 ms6169-145 date:9/6/2011 | time:post-training | group:Overweight/Obese adolescents 5 week exercise program gender=M SUBJECT_SAMPLE_FACTORS 11681 ms6169-146 date:7/19/2011 | time:baseline | group:Overweight/Obese adolescents 5 week exercise program gender=M SUBJECT_SAMPLE_FACTORS 11681 ms6169-147 date:8/24/2011 | time:post-training | group:Overweight/Obese adolescents 5 week exercise program gender=M SUBJECT_SAMPLE_FACTORS 11683 ms6169-148 date:7/20/2011 | time:baseline | group:Overweight/Obese adolescents 5 week exercise program gender=M SUBJECT_SAMPLE_FACTORS 11683 ms6169-149 date:8/24/2011 | time:post-training | group:Overweight/Obese adolescents 5 week exercise program gender=M SUBJECT_SAMPLE_FACTORS 11684 ms6169-150 date:7/18/2011 | time:baseline | group:Overweight/Obese adolescents 5 week exercise program gender=M SUBJECT_SAMPLE_FACTORS 11684 ms6169-151 date:8/17/2011 | time:post-training | group:Overweight/Obese adolescents 5 week exercise program gender=M SUBJECT_SAMPLE_FACTORS 11517 ms6169-152 date:7/1/2010 | time:baseline | group:Overweight/Obese adolescents 5 week exercise program gender=F SUBJECT_SAMPLE_FACTORS 11517 ms6169-153 date:8/6/2010 | time:post-training | group:Overweight/Obese adolescents 5 week exercise program gender=F #COLLECTION CO:COLLECTION_SUMMARY "Male and female American Indians 11-21 years old are being recruited from the CO:COLLECTION_SUMMARY Choctaw Nation Health Service Area of southeast Oklahoma. We use a collaborative CO:COLLECTION_SUMMARY approach as recently described by our American Indian Programs Coordinator (12). CO:COLLECTION_SUMMARY The primary characteristics of the three study groups are shown in Table 1. CO:COLLECTION_SUMMARY Group 1 is obese (Body mass index, BMI, ≥95th percentile for age- and CO:COLLECTION_SUMMARY sex-specific norms based on growth charts from the Centers for Disease Control), CO:COLLECTION_SUMMARY with pubertal maturation level ≥Tanner Stage 2, family history of T2D, and CO:COLLECTION_SUMMARY recent history of low physical activity. Low physical activity, defined as CO:COLLECTION_SUMMARY attaining <30 minutes of structured moderate-to-vigorous intensity exercise on 3 CO:COLLECTION_SUMMARY days/week over the preceding 3 months, is confirmed through questionnaires and CO:COLLECTION_SUMMARY use of an accelerometer. Groups 2 and 3 are both classified as normal weight CO:COLLECTION_SUMMARY (BMI greater than 20th and less than 85th percentile) with maturation level CO:COLLECTION_SUMMARY ≥Tanner Stage 2. Group 2 will have low physical activity (same as Group 1), CO:COLLECTION_SUMMARY while Group 3 will have high physical activity, defined as >30 minutes of CO:COLLECTION_SUMMARY structured moderate-to-vigorous intensity exercise on >3 days/week in the CO:COLLECTION_SUMMARY preceding 3 months. Additional eligibility criteria are: lack of diabetes or CO:COLLECTION_SUMMARY other potentially confounding metabolic disorders, able to safely exercise, CO:COLLECTION_SUMMARY willingness to complete the testing and participation schedule, and not on CO:COLLECTION_SUMMARY medications known to impact the stated outcomes. A medical history and physical CO:COLLECTION_SUMMARY exam is performed to assure suitability for the study during the initial CO:COLLECTION_SUMMARY screening." #TREATMENT TR:TREATMENT_SUMMARY Only Group 1 participants continue on to the exercise training program, which TR:TREATMENT_SUMMARY lasts 48 weeks. Follow-up measurements of the clinical and functional tests are TR:TREATMENT_SUMMARY performed at 16, 32, and 48 weeks; values at 16 weeks will be used for the TR:TREATMENT_SUMMARY current proposal to assure adequate sample size. Exercise sessions are performed TR:TREATMENT_SUMMARY at the Choctaw Wellness Centers, where fitness professionals provide instruction TR:TREATMENT_SUMMARY and supervision. Participants receive incentives for completing 20-60 minutes of TR:TREATMENT_SUMMARY moderate-to-vigorous physical activity (MVPA) on 3 days per week. MVPA is TR:TREATMENT_SUMMARY defined as exercise that elicits a heart rate ≥ 70% of peak heart rate. TR:TREATMENT_SUMMARY Several types of exercise can be selected, including walking, running, cycling, TR:TREATMENT_SUMMARY aerobic dance or other activities. To promote healthy behavior within the TR:TREATMENT_SUMMARY community and foster social support, all participants are invited to exercise TR:TREATMENT_SUMMARY with family members or friends if they choose. Exercise intensity is monitored TR:TREATMENT_SUMMARY by recording heart rate with a chest strap transmitter that outputs to a TR:TREATMENT_SUMMARY computer for quantification and data storage. Training sessions are also TR:TREATMENT_SUMMARY recorded in an exercise log by each participant and confirmed by fitness center TR:TREATMENT_SUMMARY staff. #SAMPLEPREP SP:SAMPLEPREP_SUMMARY Part 1: Longer-term exercise training study: Samples #1-133. Overweight/Obese SP:SAMPLEPREP_SUMMARY adolescents (IDs 434-001 through 434-132) enrolled into a 48-week exercise SP:SAMPLEPREP_SUMMARY program (3 days per week). Samples submitted are from the pre-training SP:SAMPLEPREP_SUMMARY (Baseline) and the end of the first 16 weeks (Post-training) times. Compliance SP:SAMPLEPREP_SUMMARY with the exercise program varies widely among participants. An additional set of SP:SAMPLEPREP_SUMMARY normal weight reference group adolescents (IDs 434-301 through 434-308) are SP:SAMPLEPREP_SUMMARY included. Note that 15 OW/OB participants in the exercise group and all 8 NW SP:SAMPLEPREP_SUMMARY reference group participants have only a single baseline sample. All samples SP:SAMPLEPREP_SUMMARY were collected following overnight fast into EDTA (lavender top) glass tubes for SP:SAMPLEPREP_SUMMARY preparation of plasma, kept on ice 20 minutes, spun, aliquoted and then kept SP:SAMPLEPREP_SUMMARY frozen. None have been previously used. Part 2: Short-term exercise training SP:SAMPLEPREP_SUMMARY study: Samples with ID 11xxx. Overweight/Obese adolescents completed a SP:SAMPLEPREP_SUMMARY short-term exercise program, consisting of 10 sessions over 5 weeks. Samples SP:SAMPLEPREP_SUMMARY were collected following overnight fast, before (Baseline) and after SP:SAMPLEPREP_SUMMARY (Post-training) the training program. These samples are serum since plasma was SP:SAMPLEPREP_SUMMARY used for other analyses. All tubes are marked with a unique ID number (shown in SP:SAMPLEPREP_SUMMARY list below) in black marker. Additional sample details on the labels are listed SP:SAMPLEPREP_SUMMARY in the accompanying Excel spreadsheet. #CHROMATOGRAPHY CH:CHROMATOGRAPHY_TYPE Reversed phase CH:INSTRUMENT_NAME Waters Acquity CH:COLUMN_NAME Waters Acquity BEH C18 (150 x 2.1mm, 1.7um) #ANALYSIS AN:ANALYSIS_TYPE MS #MS MS:MS_COMMENTS - MS:INSTRUMENT_NAME Thermo Quantum Ultra MS:INSTRUMENT_TYPE Triple quadrupole MS:MS_TYPE ESI MS:ION_MODE POSITIVE #MS_METABOLITE_DATA MS_METABOLITE_DATA:UNITS uM MS_METABOLITE_DATA_START Samples ms6169-1 ms6169-2 ms6169-3 ms6169-4 ms6169-5 ms6169-6 ms6169-7 ms6169-8 ms6169-9 ms6169-10 ms6169-11 ms6169-12 ms6169-13 ms6169-14 ms6169-15 ms6169-16 ms6169-17 ms6169-18 ms6169-19 ms6169-20 ms6169-21 ms6169-22 ms6169-23 ms6169-24 ms6169-25 ms6169-26 ms6169-27 ms6169-28 ms6169-29 ms6169-30 ms6169-31 ms6169-32 ms6169-33 ms6169-34 ms6169-35 ms6169-36 ms6169-37 ms6169-38 ms6169-39 ms6169-40 ms6169-41 ms6169-42 ms6169-43 ms6169-44 ms6169-45 ms6169-46 ms6169-47 ms6169-48 ms6169-49 ms6169-50 ms6169-51 ms6169-52 ms6169-53 ms6169-54 ms6169-55 ms6169-56 ms6169-57 ms6169-58 ms6169-59 ms6169-60 ms6169-61 ms6169-62 ms6169-63 ms6169-64 ms6169-65 ms6169-66 ms6169-67 ms6169-68 ms6169-69 ms6169-70 ms6169-71 ms6169-72 ms6169-73 ms6169-74 ms6169-75 ms6169-76 ms6169-77 ms6169-78 ms6169-79 ms6169-80 ms6169-81 ms6169-82 ms6169-83 ms6169-84 ms6169-85 ms6169-86 ms6169-87 ms6169-88 ms6169-89 ms6169-90 ms6169-91 ms6169-92 ms6169-93 ms6169-94 ms6169-95 ms6169-96 ms6169-97 ms6169-98 ms6169-99 ms6169-100 ms6169-101 ms6169-102 ms6169-103 ms6169-104 ms6169-105 ms6169-106 ms6169-107 ms6169-108 ms6169-109 ms6169-110 ms6169-111 ms6169-112 ms6169-113 ms6169-114 ms6169-115 ms6169-116 ms6169-117 ms6169-118 ms6169-119 ms6169-120 ms6169-121 ms6169-122 ms6169-123 ms6169-124 ms6169-125 ms6169-126 ms6169-127 ms6169-128 ms6169-129 ms6169-130 ms6169-131 ms6169-132 ms6169-133 ms6169-134 ms6169-135 ms6169-136 ms6169-137 ms6169-138 ms6169-139 ms6169-140 ms6169-141 ms6169-142 ms6169-143 ms6169-144 ms6169-145 ms6169-146 ms6169-147 ms6169-148 ms6169-149 ms6169-150 ms6169-151 ms6169-152 ms6169-153 Factors date:7/24/2013 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:11/26/2013 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program date:7/31/2013 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:11/25/2013 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program date:8/16/2013 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:12/23/2013 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program date:9/27/2013 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:1/31/2014 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program date:10/2/2013 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:1/31/2014 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program date:10/4/2013 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:2/7/2014 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program date:10/11/2013 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:3/17/2014 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program date:10/2/2013 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:9/27/2013 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:2/21/2014 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program date:10/25/2013 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:3/17/2014 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program date:12/23/2014 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:4/28/2014 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program date:3/14/2014 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:5/16/2014 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:9/5/2014 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program date:7/18/2014 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:11/25/2014 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program date:10/30/2014 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:12/12/2014 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:5/8/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program date:2/20/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:7/20/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program date:2/20/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:7/20/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program date:3/13/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:7/21/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program date:3/13/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:7/21/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program date:3/27/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:8/7/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program date:3/27/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:8/4/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program date:3/27/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:8/4/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program date:3/16/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:8/11/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program date:3/16/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:8/11/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program date:5/5/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:5/22/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:9/25/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program date:6/11/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:10/28/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program date:7/14/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:11/6/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program date:7/14/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:11/6/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program date:6/30/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:11/23/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program date:6/30/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:11/17/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program date:8/17/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:2/9/2016 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program date:8/28/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:2/9/2016 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program date:9/1/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:10/23/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:3/4/2016 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program date:12/18/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:12/18/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:2/8/2016 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:2/8/2016 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:8/29/2014 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:12/16/2014 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program date:9/18/2014 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:1/20/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program date:10/10/2014 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:3/4/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program date:11/28/2014 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:5/8/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program date:12/4/2014 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:4/10/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program date:12/11/2014 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:4/30/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program date:1/5/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:5/8/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program date:1/5/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:5/8/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program date:2/13/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:6/8/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:10/5/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program date:8/4/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:12/29/2016 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program date:8/5/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:12/11/2015 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program date:8/18/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:1/15/2016 | time:post-training | group:Overweight/Obese adolescents 48 week excersise program date:8/21/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:12/8/2015 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:12/29/2016 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:12/29/2016 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:1/5/2016 | time:baseline | group:Overweight/Obese adolescents 48 week excersise program date:8/4/2015 | time:baseline | group:normal weight reference group adolescents date:8/4/2015 | time:baseline | group:normal weight reference group adolescents date:10/19/2015 | time:baseline | group:normal weight reference group adolescents date:10/15/2015 | time:baseline | group:normal weight reference group adolescents date:12/17/2015 | time:baseline | group:normal weight reference group adolescents date:12/17/2015 | time:baseline | group:normal weight reference group adolescents date:12/23/2015 | time:baseline | group:normal weight reference group adolescents date:1/9/2016 | time:baseline | group:normal weight reference group adolescents date:6/8/2010 | time:baseline | group:Overweight/Obese adolescents 5 week exercise program date:7/15/2010 | time:post-training | group:Overweight/Obese adolescents 5 week exercise program date:5/25/2010 | time:baseline | group:Overweight/Obese adolescents 5 week exercise program date:6/25/2010 | time:post-training | group:Overweight/Obese adolescents 5 week exercise program date:6/1/2010 | time:baseline | group:Overweight/Obese adolescents 5 week exercise program date:7/14/2010 | time:post-training | group:Overweight/Obese adolescents 5 week exercise program date:6/2/2010 | time:baseline | group:Overweight/Obese adolescents 5 week exercise program date:7/14/2010 | time:post-training | group:Overweight/Obese adolescents 5 week exercise program date:6/23/2010 | time:baseline | group:Overweight/Obese adolescents 5 week exercise program date:8/5/2010 | time:post-training | group:Overweight/Obese adolescents 5 week exercise program date:6/23/2010 | time:baseline | group:Overweight/Obese adolescents 5 week exercise program date:8/5/2010 | time:post-training | group:Overweight/Obese adolescents 5 week exercise program date:8/10/2010 | time:baseline | group:Overweight/Obese adolescents 5 week exercise program date:9/29/2010 | time:post-training | group:Overweight/Obese adolescents 5 week exercise program date:8/30/2010 | time:baseline | group:Overweight/Obese adolescents 5 week exercise program date:9/30/2010 | time:post-training | group:Overweight/Obese adolescents 5 week exercise program date:12/8/2010 | time:baseline | group:Overweight/Obese adolescents 5 week exercise program date:2/15/2011 | time:post-training | group:Overweight/Obese adolescents 5 week exercise program date:1/6/2011 | time:baseline | group:Overweight/Obese adolescents 5 week exercise program date:2/14/2011 | time:post-training | group:Overweight/Obese adolescents 5 week exercise program date:2/18/2011 | time:baseline | group:Overweight/Obese adolescents 5 week exercise program date:4/22/2011 | time:post-training | group:Overweight/Obese adolescents 5 week exercise program date:5/20/2011 | time:baseline | group:Overweight/Obese adolescents 5 week exercise program date:7/7/2011 | time:post-training | group:Overweight/Obese adolescents 5 week exercise program date:5/3/2011 | time:baseline | group:Overweight/Obese adolescents 5 week exercise program date:6/8/2011 | time:post-training | group:Overweight/Obese adolescents 5 week exercise program date:5/3/2011 | time:baseline | group:Overweight/Obese adolescents 5 week exercise program date:6/8/2011 | time:post-training | group:Overweight/Obese adolescents 5 week exercise program date:5/26/2011 | time:baseline | group:Overweight/Obese adolescents 5 week exercise program date:8/5/2011 | time:post-training | group:Overweight/Obese adolescents 5 week exercise program date:7/13/2011 | time:baseline | group:Overweight/Obese adolescents 5 week exercise program date:8/25/2011 | time:post-training | group:Overweight/Obese adolescents 5 week exercise program date:6/23/2011 | time:baseline | group:Overweight/Obese adolescents 5 week exercise program date:8/10/2011 | time:post-training | group:Overweight/Obese adolescents 5 week exercise program date:7/27/2011 | time:baseline | group:Overweight/Obese adolescents 5 week exercise program date:9/6/2011 | time:post-training | group:Overweight/Obese adolescents 5 week exercise program date:7/19/2011 | time:baseline | group:Overweight/Obese adolescents 5 week exercise program date:8/24/2011 | time:post-training | group:Overweight/Obese adolescents 5 week exercise program date:7/20/2011 | time:baseline | group:Overweight/Obese adolescents 5 week exercise program date:8/24/2011 | time:post-training | group:Overweight/Obese adolescents 5 week exercise program date:7/18/2011 | time:baseline | group:Overweight/Obese adolescents 5 week exercise program date:8/17/2011 | time:post-training | group:Overweight/Obese adolescents 5 week exercise program date:7/1/2010 | time:baseline | group:Overweight/Obese adolescents 5 week exercise program date:8/6/2010 | time:post-training | group:Overweight/Obese adolescents 5 week exercise program Histidine 136.275783 124.1256828 173.9551187 156.1868002 163.1840099 140.4445546 140.6234026 151.9121127 158.9851052 162.2473252 153.144329 143.3058472 137.2749235 152.3563937 139.9421439 118.8839165 144.0658879 125.2089038 123.4591115 111.2763993 112.1587986 132.0185934 146.6197594 157.537506 148.7490241 150.779157 151.0946524 156.7010765 151.4924422 143.0877086 169.4842801 151.592429 164.5912642 101.1710342 123.125648 146.1029289 149.2212161 179.2775846 166.3582 105.1308544 111.8020009 106.720225 112.2154956 87.17752564 100.3373473 95.80769921 93.19137395 117.0027611 85.56826835 90.50135886 95.89699666 102.0149963 85.85633366 106.2237683 89.22059511 111.0717256 105.5710179 126.4378111 106.8790862 123.4319625 89.86346581 92.66613397 98.85128036 105.4340852 126.3072996 103.7844432 110.1244872 116.9683984 129.4148917 74.70012161 90.6242197 125.2041076 120.9226118 109.6882254 105.2330105 104.1897589 109.3179143 106.2303851 107.1170345 111.3262928 95.15840895 119.4184417 109.8982022 97.52771748 118.21356 107.0855705 116.7849496 127.3901358 89.38672464 79.13967131 90.17057792 74.39857529 95.76897648 109.9112337 108.4904699 117.6872465 98.35776239 105.28112 86.50330974 87.20553203 163.5683855 98.26162507 106.9995309 127.0635189 99.35398936 101.3211793 107.6870543 118.2575264 105.84076 94.0405216 97.03947575 100.8046623 121.4742075 111.422239 107.1766575 78.41476687 100.8819131 96.36476255 103.6680806 114.9033794 124.8245988 112.0592004 177.8354147 80.24919471 79.32136543 152.9349543 140.9150659 125.2001168 117.8646655 116.9105866 134.9990044 118.157437 120.4064492 148.8229934 153.3747048 128.9075492 117.2889501 112.5037061 129.3969223 141.4240955 129.1987947 96.94675681 109.56397 103.5190423 91.53785408 119.9430508 133.3080202 101.9661982 135.1971459 125.30432 129.0895665 120.9455435 89.74028332 Hydroxyproline 22.01483293 31.736123 24.37409784 42.9088185 17.21447118 17.37000647 19.74771869 26.06881794 15.4552698 11.05478472 35.87517395 22.14517294 12.14549852 18.20860125 27.48282809 33.58465405 21.80023525 11.17193953 15.40346878 17.90268721 14.68086679 18.46480251 14.60842209 13.64136929 18.22979078 21.97315227 19.0425394 14.94894123 33.66848504 22.28179043 12.63242 20.77225361 14.10247268 22.24605712 25.58327111 30.43734768 31.01442376 23.67531845 21.30464212 20.28440302 29.30760275 23.26153904 25.12507007 18.90119123 25.26993623 24.10007035 25.27477436 24.72558452 19.07150927 26.21380833 15.09281444 25.78732453 27.33566901 15.00584675 14.49009206 10.6758676 34.74916484 16.94268815 8.33901185 9.397949927 24.8451487 24.21186952 21.9571177 19.00495105 20.8540644 15.98432551 22.28387246 15.24278391 16.97429077 27.19544236 30.78979645 23.21933418 14.53934146 8.327324866 13.66110969 18.5190666 18.034877 25.9991432 19.63955112 27.94851568 25.75985964 51.22081972 20.19126955 12.21378201 18.33564947 22.11271289 18.64467808 24.9681219 24.41148742 17.59831879 24.61388294 10.31464567 29.93462731 23.12920109 24.1372727 13.60741339 27.41781336 20.63472155 13.22111647 10.45606677 26.15396672 17.55103579 25.38531883 58.42177531 18.28813518 15.8495804 23.68380274 23.95562172 26.66619549 25.94039906 21.97550917 27.87892757 23.44976965 36.3381675 23.0496416 43.68565109 34.53487809 17.44034347 12.91228973 15.96913689 15.71504788 17.58480319 27.33321758 31.80551653 20.40804146 27.67792822 22.21432471 19.69743798 18.22320686 17.406876 17.85324919 19.08244745 35.38636602 14.69198844 13.06992439 27.38404893 28.40022492 17.78313214 16.41174438 18.34981117 15.84959223 14.4142236 19.14068833 16.36956853 18.84109117 15.15871966 15.23132006 17.60374311 21.55128782 22.65368382 13.24826589 7.355764159 11.50252948 1-Methylhistidine 1.188706392 2.317955383 0.799143124 1.8487781 8.522967781 6.964484398 1.917576125 8.900125156 4.25173535 2.130435863 12.19368557 2.889425484 12.52808521 1.362638441 2.653706095 1.249463749 3.638090669 4.66789894 0.807570397 18.52737326 9.322322334 11.77096523 16.47106367 6.724966666 1.713350134 2.053874105 2.752261972 13.33824919 1.721922908 4.969561687 1.968964541 1.208184156 2.240322097 5.117548612 9.040719673 1.943117983 4.245072182 10.80423854 9.025342872 0.224879244 4.912164978 15.20237431 4.280155471 0.51296936 1.545501246 0 0.599015069 1.854557263 22.72615596 23.12436096 2.227009131 0.327299052 7.033204277 5.551956572 3.131322235 1.043922376 9.195052991 5.140635345 -0.345063966 0.964118823 3.270955068 12.81313495 48.43966174 13.23537451 0.420736995 28.46752362 22.17674482 2.366634115 2.34434027 13.70440942 7.917042707 2.294778881 10.86319432 0.380957818 4.771650866 20.63048139 0.569384448 2.395579636 1.787014129 1.318320663 6.922885125 3.027382683 0.934006759 1.983167362 2.826304993 2.712549087 6.050724389 1.631253923 2.816439817 0.935273708 2.922753236 0.859912163 1.530311216 4.803951481 2.536004552 0.888597766 2.30843279 3.169048159 1.206872437 1.119388302 21.12327431 3.457274514 1.614034152 4.89839759 1.112193776 0.933266514 1.146739774 10.31054973 1.547375475 0.897132016 2.280595069 1.535165345 1.136553228 6.12516341 7.592425703 4.823920923 2.78051518 4.469177396 3.755020837 2.905948738 2.428667467 7.251231842 28.77293389 4.5933315 10.52814537 4.100478938 14.04456983 1.399179296 2.492074637 4.729886312 1.823302728 14.51393537 22.59806869 4.91937547 1.209238813 28.77226611 4.954295779 3.159451236 2.752436792 22.87888369 3.02031721 1.312321411 3.686334804 6.473847675 2.336686649 31.49551624 19.78313599 8.304796587 6.932864586 8.972646712 7.471678461 12.23547794 10.55756504 3-Methylhistidine 4.185309419 2.563225372 1.931442823 2.44306869 1.327866655 1.429049858 2.743689314 4.581203448 2.601141485 2.910495482 4.09165159 3.991161889 3.220876869 2.175794993 4.111849046 2.591025245 1.639378284 4.923763022 3.931960352 2.954944441 4.053050304 2.693663698 2.088529182 4.331251034 2.839807696 4.317256497 4.729987512 2.229017519 1.153613015 1.90632947 3.096823165 1.955932373 3.275796044 1.780326653 3.19009111 2.417277058 2.104260253 5.1700058 6.931298658 1.489702671 1.865211518 4.669829836 2.582221685 3.791045082 4.762711842 2.797741151 3.512434687 3.872830105 4.097537975 3.359733006 1.600548229 2.432848038 5.868503815 5.437164118 2.777555043 3.514042078 4.089492391 2.979125363 2.21997022 4.105604439 3.929475063 4.876353737 4.550539538 5.214075145 4.117097503 5.083991753 4.954917994 3.589026889 4.022840489 5.089633044 4.481619867 3.188107479 3.707101929 1.93668956 3.470045264 6.002387293 2.827146532 3.966914517 2.960549233 4.503030144 6.421965091 5.348984906 3.561109579 1.963818981 3.201988022 3.501921019 4.555026101 3.735303267 5.012577656 3.752026563 2.740493094 1.521308927 3.048838872 7.129881528 4.66828778 5.743439249 4.434999547 4.988675895 3.802867509 4.649493279 3.378926562 3.378119324 4.016983378 5.246242409 3.747164891 4.661163076 2.87722132 5.013041159 5.851091466 2.551513329 3.287103934 7.180670994 2.554264367 8.01579726 5.882495397 4.652907647 2.992996125 4.253430815 3.563274282 8.568514927 6.98219193 6.400812034 8.007811789 5.943359198 4.782305156 12.13735142 5.879837196 3.717755062 6.886300673 3.072306796 6.207043574 7.71014048 4.582517873 5.620777941 2.729911989 6.181296221 8.982246884 3.367300008 4.669417718 6.447491294 6.361889332 2.679231639 4.466479722 2.393097378 3.85082608 9.704541655 6.739227314 4.08011035 6.200028406 6.442642083 5.903294354 5.748667933 5.337466471 Asparagine 30.36800763 34.80720293 37.46431978 32.10722661 47.21265435 32.60833896 27.65401791 34.07261069 34.339102 43.92262631 37.63773044 31.77148099 30.56340136 27.94804995 39.73083752 26.95431607 27.47242213 29.00144487 38.20061514 19.34289496 19.0207858 15.32778679 40.87431757 43.5622653 36.4657117 44.04679419 33.85335177 37.93182506 37.47399409 30.23179326 31.56567551 27.69192277 30.68529741 31.03842895 26.54086046 30.28500539 23.5730479 63.10425917 32.31440574 42.36300884 34.88354017 41.26966768 31.32995535 44.22252828 44.77647636 32.88494504 30.03135347 32.86191992 29.59622326 34.15153159 35.9443519 34.27958278 26.99519264 39.65294066 27.59098413 40.20697033 30.67073353 51.0943156 32.00512714 43.75311102 30.15179975 36.03886099 30.68120045 34.3266642 39.26542039 39.12901607 50.07294313 37.30619665 41.65237156 31.42510685 37.0318105 47.01919337 52.04637707 41.77340295 40.42960992 41.41668845 41.29348405 31.76295153 36.16121153 53.16668678 50.63945906 39.89313528 34.62534045 42.72803444 43.8001221 40.56355057 39.95175279 46.60257399 40.72469736 32.14012066 29.91312379 28.28297205 29.67779489 47.17164483 29.05663735 35.73697988 30.35460066 46.80014072 41.67069638 41.21540576 48.40226436 30.23041703 32.43557265 58.02605877 24.70982895 60.31158035 47.4018115 36.84688313 46.07114528 56.00521299 46.5968543 47.45438301 53.88490453 63.47997655 56.15500542 42.38869935 54.80977498 45.5544086 56.29546318 57.52025171 58.0525165 49.82796146 71.01184573 38.175767 36.1127713 43.35838153 44.86479189 46.66470466 41.4584022 50.38780382 45.4745478 41.90360095 45.84519905 50.68308756 51.67529842 57.34401229 54.58255815 53.9859323 46.91891535 50.06945559 59.0389129 42.17972947 41.49221371 49.11997453 47.17428425 47.14626574 50.30789371 40.65796593 42.84811385 40.09378625 58.47930946 54.98564422 45.51726809 Phosphoethanolamine 0.559387484 2.154414333 0.761841101 1.756391389 1.857477759 3.352501562 0.59085519 2.307135625 5.243790064 2.056412687 0.648181579 3.860534133 1.090544116 1.298161818 1.704085128 2.519423982 0.917784023 0.859899658 0.643983517 3.893094498 0.606787684 1.411915033 1.06281317 1.467374659 1.246245986 1.931316837 1.822976239 2.156167023 0.91827538 1.079003332 1.654053632 1.125207897 1.178003491 2.519736589 1.942184653 1.207622061 0.714732112 1.862898372 1.333033162 1.089977795 0.889986905 4.436892861 1.713517711 2.683587395 1.213453817 0.75318086 0.707193795 0.559682294 2.245370198 0.7571033 1.177499723 0.669611029 1.723457756 1.18917752 1.207658314 1.034466658 1.11154221 1.65651104 0.825223531 0.978589366 0.77116029 2.444833841 0.303440436 0.650768353 1.114336443 0.995078192 1.971501943 1.157805064 1.026074256 1.911810121 1.218021626 0.830911846 1.273806343 2.499023275 1.662160008 2.577864911 1.357708174 0.709849996 0.930886861 0.901819475 1.039665912 0.868819542 1.459000738 1.614386133 1.582042286 0.94783544 1.188217783 0.813074916 0.898225819 1.283195653 1.025488204 1.270492822 1.216953761 1.028047491 1.267851252 1.063888871 0.54148359 1.773745552 1.152716377 0.90879744 0.650787732 1.07954859 1.504200784 1.047271382 1.445932862 0.438309286 0.799387828 0.828026205 0.612929457 0 0.100269228 0.097137589 0.093722727 0.128262704 0.121436142 0 0 0.206061862 0.211546491 0.039497888 0.116896002 0.724331883 0.304956018 0.098582463 0.065558095 0 0.016748542 0.01315304 0.010278455 0.308093979 0.012219093 0.713230098 1.055956097 0.023310093 0.038517245 0.009379426 0.013783378 0.228574978 0.280331684 0.571792665 0.232109584 0.231149944 0.378063333 0.015069641 0.02471327 0.949236971 1.080522847 0.020425607 0.114286035 0.429193288 0.369052025 0.998644572 0.98941911 Arginine 68.99693292 87.42639949 67.38636112 65.37846616 79.08213111 74.2092635 54.36647117 62.60086751 72.19750933 81.5980715 101.6733455 57.28047886 51.29995918 55.31478334 85.0205402 49.02275717 59.26448249 67.45294911 79.93936293 63.72276128 72.01500625 72.35412461 59.32709596 56.89114092 60.5871412 75.12796207 69.81905495 71.7000813 79.17187374 81.70709845 77.01858766 73.60442378 75.23820928 52.6810914 50.96059731 53.47386257 63.16230917 84.05111994 52.91027804 59.50302908 66.19184427 87.93085176 70.82349637 103.9201071 100.3876754 77.66956956 139.3271516 80.13957289 71.4272002 69.06778724 82.69361178 121.6432044 55.86041856 91.90223494 64.74357532 87.41679609 82.95907372 95.26058534 81.4991432 94.62379557 79.15926354 91.29445603 55.55139002 74.8927321 88.86923145 80.92414468 88.63613873 80.12091663 109.0653465 67.49934328 101.20666 73.78963765 78.62262528 82.45411893 84.66136479 66.59844119 60.39411374 85.71019998 80.48997641 92.31448877 84.97238162 89.17326754 72.06892232 75.42935915 74.19823732 84.56889212 74.35369314 94.30401713 71.33556988 54.57838732 137.4402246 56.05623253 93.08052549 83.25543448 96.61125432 76.62833602 100.9646805 92.45918951 70.20044539 68.31996955 94.28100591 73.35131656 61.68311159 109.643128 61.80108691 84.93492182 90.56936806 53.61409288 73.51848899 133.5227267 118.9061043 102.0123629 102.5048752 102.2044196 94.23428 76.98689708 101.1525884 104.0740687 97.45214904 84.33135955 97.00238535 98.19709071 139.8349137 80.00876537 85.91092735 120.0182235 94.77933505 107.2382415 117.8608139 98.02223616 98.79559824 79.07610104 100.3985487 108.335918 104.5231446 123.8689615 99.8858092 124.3366132 113.4516977 68.77755079 85.1236558 91.24076551 116.5405783 105.202595 102.2659062 75.9010342 80.38788073 80.27259579 109.9198206 64.10288011 88.58267114 93.86262629 81.33056756 Carnosine 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Taurine 32.7866861 38.16147591 40.29491274 48.32532868 41.79881145 60.48132066 39.42365935 49.62104467 90.20797221 36.23139311 40.52358948 44.68485396 27.58688545 33.85325678 34.04096758 33.18723609 28.85325817 32.27367758 35.75089121 51.46825276 28.86177894 27.65795987 34.81761808 32.67719604 32.64158688 37.8130279 26.06330647 33.29427086 35.94953876 24.05859217 29.65240189 27.15497614 30.32303249 38.45753888 35.94702703 34.4608048 33.46680975 35.8803987 31.98145344 33.57384288 45.22154123 88.72059121 46.38060706 54.09882782 39.77185177 48.81694269 36.62016873 43.26507822 58.07256272 39.82732892 38.1124082 36.48605416 42.06767923 42.2590981 46.1629032 46.68441248 40.35106077 47.82567714 49.64750434 56.34515762 36.25106118 64.19149733 46.61219369 40.43727856 37.17086202 50.95295264 49.54976359 54.6564486 52.02697623 58.6944516 49.86212581 51.06849575 49.78043244 55.33522337 47.64511673 80.0523593 46.18905487 56.68511971 37.34673928 35.66546966 39.90961525 47.31445192 41.35604549 48.87755019 51.94917021 49.42692236 38.1425463 45.22116887 32.41049977 37.12565113 32.2713906 32.58376376 54.3805528 29.03446612 42.7151768 37.13456613 45.94772717 57.65818877 34.88855834 43.02008226 50.73814218 45.80486484 58.03847402 39.63109995 56.97103187 35.82285601 40.93841122 50.52901131 41.6503362 45.53066516 59.14621126 78.6995447 42.37867892 93.97112871 93.18074588 78.36965537 88.26638513 56.97600047 92.8933609 50.05588667 68.10799873 98.22710928 93.27352553 57.32324629 47.58808698 52.99517582 43.39966109 56.0577194 54.72467198 47.03226945 42.83872627 37.91222273 91.6370073 33.03754162 88.62850129 60.25776104 45.69843911 69.57816193 63.18370362 63.06301695 58.00942593 42.73026586 88.2420637 91.92884836 103.301276 80.05985273 99.98288721 48.30427897 82.93138302 53.99451944 57.8289474 91.45989417 71.70380474 Anserine 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Serine 70.46371605 87.25729305 98.51312505 99.77185258 78.66818704 85.48058593 53.61771044 60.8633043 89.74105965 105.1180253 78.43055754 84.84851694 59.54426773 74.57065678 93.42389608 79.2965072 85.00530102 71.58804954 87.51655711 71.13118804 80.94902464 111.1186193 81.08167982 82.98064985 97.722633 99.91100724 86.47933142 69.08792197 76.45328342 97.4308693 97.89254698 82.89593804 94.01803012 67.7267353 62.0660509 77.75031339 64.65335336 84.50733578 60.77549173 106.3208752 102.0187635 95.55738777 89.94325193 81.93349471 75.7040592 76.49637399 128.4477889 100.4987457 72.36098547 88.95670135 71.12781486 85.1331666 90.90835245 103.296248 92.59946393 95.1525018 87.06422769 104.328155 87.02561343 84.71311887 88.58120496 83.82857597 80.35727873 89.61755748 81.86641587 107.9295941 114.3931917 80.22993917 103.1501104 68.44507135 90.53382908 114.7074915 107.6688163 129.1588266 116.52661 93.99165404 76.87741597 81.20533005 73.52361981 119.1059483 103.0885782 108.7192344 83.89873161 111.1072637 104.4719757 96.45836281 100.958497 71.55510966 101.3147748 104.3566061 141.0044165 90.30747924 73.98984975 93.08676251 105.3298883 93.53187761 99.58015606 94.30700228 131.7986222 135.5615183 102.0634872 81.85486759 75.20005811 147.130794 96.8986133 103.1411031 118.7466357 116.0066943 81.9185689 138.9952613 134.2737065 164.4947601 166.5410759 97.10296544 110.5406982 107.3751931 134.9861788 149.938079 181.4490477 133.5090606 132.3003446 129.6135319 187.9113441 124.3491162 129.5898933 126.9684271 135.7042551 111.0470333 100.9291499 128.2263855 115.975855 103.2220517 132.9640914 92.12209761 97.69312099 118.3093269 101.8105224 130.2612681 128.9005107 133.7164457 149.5507919 157.7395646 158.5962926 133.8597347 113.9311896 111.7602295 120.1531426 91.2892542 98.58726814 113.902783 128.9118548 147.3825339 142.485232 Glutamine 338.8330054 273.5265755 548.4815785 361.8188186 573.5761132 290.8475609 498.8409884 429.1097993 567.6323019 515.2857273 668.5873244 491.7619651 432.4540021 305.761032 570.1917514 440.491711 471.5386357 322.1544229 291.3640716 219.5276663 291.9756111 165.7906701 386.8371775 467.2453713 524.4224776 536.4243437 433.7439315 491.0539632 400.5234374 387.3579223 348.4018345 414.900692 399.0648868 296.0825548 252.3938765 360.354919 294.5166214 569.8046836 299.3975475 454.0414832 412.361729 394.9815638 330.2126996 487.8575086 440.4655969 369.2754769 329.2217339 450.0983199 419.4329123 502.7859171 402.7822966 466.1566179 316.5986975 542.9196772 330.6887165 565.7839465 383.0808282 596.7049105 357.4925411 590.9770254 473.0842488 569.345567 394.651335 511.383502 497.9089386 507.1365692 692.5692732 416.7417669 487.5923157 406.9434998 523.6855872 579.1223887 547.9299289 597.5614569 563.5462314 534.9694957 552.1982637 563.4396837 557.1746026 565.8947921 509.1050548 591.2077092 513.0304933 628.2437025 607.8396667 504.4404079 577.8256915 600.0458277 537.3876589 506.2223758 396.4403373 424.6637412 519.5878406 605.7686908 442.5128362 592.260741 497.9064941 563.6137746 536.8285871 578.6966939 653.117764 453.3585941 492.3054415 648.0190643 516.4202882 724.1279772 649.4807989 524.2121048 626.107869 679.6143294 571.4069289 664.6193147 757.8821406 642.992774 589.7122907 466.5401152 546.8162159 573.7433663 653.9892733 680.5142075 865.6874149 726.5125773 896.2068883 568.8173505 614.3816378 651.0524401 629.3859689 501.5243889 518.0235787 686.1387937 634.7551748 587.8893976 654.1535968 544.2431179 515.4756339 730.187646 647.1579151 720.7514498 586.9875141 577.2069347 605.1234643 609.7492679 621.697126 644.9592432 657.6257499 666.8009792 711.5226319 563.0707765 598.0979266 703.8947355 697.5989458 587.8141369 586.4875294 Ethanolamine 5.81482244 6.507432596 7.053351921 7.134744096 6.307486977 7.366567286 7.274858992 8.490043158 6.261887991 7.374052324 7.743120428 5.970750071 4.442862462 4.707825523 6.012168907 8.179571693 7.486153532 6.529874876 7.597557617 6.012554793 6.15234395 6.359391089 5.688747724 5.628423038 5.354339639 6.506098741 6.411669945 6.772668312 7.75181546 6.86681242 8.870961822 5.369758352 6.791339435 4.553920743 5.605594033 6.083786153 6.943074583 7.04643459 5.767577222 5.979105284 6.553308962 9.790259466 8.681852626 6.044035854 7.006104905 7.130030485 6.681425083 6.662319918 6.731498521 5.578091155 6.850772493 7.778381518 6.758165963 7.528517583 6.177022339 6.684002607 6.483378136 6.544529842 5.988466109 5.802301676 6.988367465 6.604059756 6.377757892 5.676691495 5.467595473 8.042954581 8.905656931 7.224022111 8.562691481 6.615851768 8.11725356 6.70661035 5.961162547 9.258461623 7.990886814 5.502643859 6.140370582 6.659488486 6.790408162 6.673135212 6.723681796 6.780220189 5.444695878 7.560369983 6.077608123 8.001385278 7.506204263 7.518398692 8.403968413 6.969259304 6.65515968 5.685559571 7.541322463 6.480136992 5.885776526 6.270894453 8.217098407 9.056540174 5.818641017 6.757479915 8.098895603 7.137998223 6.650201488 9.601329325 7.309213393 7.586020981 7.198876018 6.933001515 7.937642544 8.930288917 8.746074164 9.052245024 7.772703031 9.832485617 9.284168961 8.754398571 10.28308742 9.150316842 10.06582208 7.535295314 8.632042651 6.951746393 9.099994721 8.439656625 8.621259616 9.364437185 8.587836523 9.59598018 7.728181419 8.434438156 7.963538939 4.970106029 5.399892712 7.184673771 7.117118427 8.712025806 8.330312477 7.879025084 6.883481067 8.275099733 9.273182166 6.427367677 7.079579549 8.255505339 8.080703141 7.569108579 8.791978293 7.76505798 8.372063348 7.081581712 6.053180387 8.06409987 6.903116555 Glycine 149.2737668 199.1020774 277.4513087 266.4407316 182.2773983 190.9887991 179.6513438 188.6864442 166.4651637 199.730244 242.2294311 201.953369 149.1820579 191.3928378 218.6834845 144.9467519 155.9268432 205.222866 268.8144979 170.987265 207.0373675 185.8772119 177.2453399 183.2697093 217.045482 249.3715476 192.6496466 186.2312472 238.8570562 258.920982 208.670763 239.9310531 274.5102898 168.58945 158.6070775 216.2810051 204.8544463 277.4901538 202.8485134 229.4353801 243.6695393 207.6592563 214.9713452 207.0034862 251.1719725 165.9267908 187.1547747 218.8361147 275.4528838 267.726706 164.9757613 190.9885562 188.8818744 245.640201 213.1808054 250.3170918 303.6288857 287.5650467 201.9778727 235.5443386 237.0907142 214.182969 249.9159838 244.941719 267.1476506 223.3396837 247.3804763 241.1283938 255.1610723 212.8945485 234.6969235 190.6116051 190.6086416 281.2790641 255.8180089 205.5862831 214.8998685 214.7244472 200.0052784 219.3670056 202.6490132 204.6117967 178.89847 219.1427819 241.5938307 226.2537404 207.3439658 173.3807245 200.328033 206.089963 239.0045636 158.6184914 239.6120093 214.9413349 216.9434336 237.6683769 205.9414258 289.579927 278.2309359 252.745952 212.004237 216.7202693 204.9704082 416.7409469 233.4865208 332.2833096 324.4154452 257.3114527 304.751038 315.2436561 261.3005109 382.9746747 399.0227041 266.2583653 234.3947923 319.1539635 306.1644116 296.6443586 329.837288 316.3157149 375.4450621 341.0526237 418.7813271 244.2908139 239.2421445 225.6497482 236.8509352 270.501942 239.9145746 274.5502412 273.487188 200.8353688 272.6423367 217.7708939 200.709014 337.9434085 323.0269689 282.6072652 243.5367123 250.723657 328.7226933 304.4201545 330.1423644 322.358523 314.0977434 205.0293904 216.6104646 157.4838485 156.3299213 237.4126232 222.0612033 347.3614194 331.8903596 Aspartic Acid 5.191360012 7.546261481 3.172894517 8.797591419 2.226796051 8.688824801 3.100773473 5.743220293 6.503386201 4.287756313 4.415227296 5.443343964 2.648348333 7.4031918 4.419501507 2.960211239 2.912940473 7.929559005 11.5192699 8.866595054 7.310027236 13.3078244 4.911231848 2.767716143 3.634459082 3.859601595 2.937459108 2.845162978 4.604953839 4.858128188 8.229550213 5.468895004 7.322952045 5.678367077 6.275302374 4.724103556 6.013642093 5.665295215 8.520673705 3.605920156 5.335147523 6.818635342 6.027001053 4.872293909 5.069736132 5.8741346 7.284920909 3.953878313 3.2725859 2.220827417 4.743950441 7.973587052 6.828491258 3.811712899 7.832432691 3.970497291 5.907060385 2.543724999 6.92592572 3.112915977 8.500683896 6.001891673 5.543607134 3.882293132 3.933128139 4.090666695 2.521598312 4.789856504 6.120058676 3.439555439 6.090746885 2.786456616 2.907433758 2.61716159 2.006171506 3.04814466 1.771382818 2.467116333 1.620247066 3.631352691 3.955945546 3.420588515 3.675335048 2.632500502 2.979805151 2.231863982 2.426288093 2.649078908 3.839968366 4.813052199 8.143871719 3.601115045 6.867994952 3.564620373 9.391155702 3.03201961 4.885147461 3.102444945 2.850769495 1.679426005 2.95153403 10.24502935 8.64961698 7.884809757 7.077134519 1.447752181 1.771965658 2.178766233 2.126613351 32.47812388 26.7177805 25.59966821 21.83491681 16.42687165 17.13219814 23.86143457 24.14766857 22.26029161 22.11836881 15.29720307 14.07441838 16.11623698 27.9864523 30.88350095 23.4323721 30.1662088 26.0985942 35.25091776 34.16147136 12.3346375 19.65486567 10.05972441 17.00000971 29.48459791 31.01329199 27.20125067 24.49052851 17.21027187 13.25157657 15.78439159 17.80626268 13.98036745 18.61774085 35.1459641 24.25231332 21.5857892 19.72044886 13.98201188 15.97071624 17.72344105 19.26728396 24.19794019 22.73440421 Sarcosine 27.57214867 7.88615788 18.63617587 8.160427001 3.908298307 9.747592177 11.89798706 11.05636442 7.211130881 10.61671203 12.76871134 7.767588494 10.82952731 14.33328443 8.133610688 10.81004205 13.34963661 9.507921399 18.32985269 9.499042523 18.77659085 14.17449509 21.50906912 18.32635897 21.93809027 14.00576333 12.51464163 11.84711634 16.70885702 17.9408103 19.81589211 15.11799481 20.15192595 15.7357201 20.44421422 16.86229837 26.29593336 14.78959703 19.16675398 17.22929534 13.52597802 13.96537537 18.33855167 11.11789854 20.98976991 18.67195766 34.39732273 17.40735205 14.84302923 18.32081152 15.33562332 15.05683156 17.82188924 20.0467994 15.58841553 19.68301107 17.05270862 21.26825302 14.5488558 19.011309 22.64766075 19.45838886 81.19865929 34.06001065 19.86187207 23.3541393 20.65727882 20.36893086 23.9999113 25.56415323 18.42173999 16.11557408 8.80493213 15.08379829 11.69035089 12.99622884 13.40065521 15.09018465 11.90939859 15.70020031 13.61843682 16.95500176 10.9164814 8.495595185 9.815772896 15.66705523 12.2684482 15.90136346 13.41531555 13.93421643 15.72104058 22.91246383 13.86008214 17.07405953 14.98647503 15.0425834 27.6067994 19.57251926 14.02292009 17.71165775 17.40085704 14.70675514 12.03990778 19.39548991 14.02298857 18.18789437 17.36946864 20.49447559 15.8431219 1.040227995 1.014127511 2.381516483 1.74636939 1.926404577 2.354092521 1.36222454 1.916205155 1.457442022 1.782296495 0.98820454 1.069737451 0.921335897 1.518581592 1.424499192 1.21031038 1.751926297 1.264253878 1.412604757 1.591473958 1.178929239 1.183210976 1.186536 1.227628417 0.839352456 0.889919977 1.339923211 1.475859688 1.291591088 1.154564149 1.307085684 1.215144358 0.87304654 1.018142313 1.201659503 1.016210298 1.411105263 1.399136138 1.257115462 1.312040206 1.137538821 1.145162476 1.712258379 2.059189322 Citrulline 33.30054738 29.03371492 32.65853251 35.0551989 37.53216596 39.60366106 32.97860594 29.57570279 32.93205072 32.74740173 45.41779948 26.69255656 19.7497255 21.84746001 35.40924154 17.30869559 20.60941219 23.97375564 31.47167409 22.11072726 27.18706163 25.9900275 27.76463139 26.27628308 32.76327978 35.14560649 24.34492037 24.8154 37.16088961 32.9083988 34.36409113 30.58207446 32.96743246 21.46862572 26.17608518 28.09888351 33.51246236 44.40067927 33.31356374 20.45485242 28.39546401 22.00360296 16.60077843 31.68900647 32.05805428 28.57746501 25.44645589 39.6519574 33.02896931 40.95112079 29.72540479 30.31040086 29.79817039 33.21595332 31.81815785 28.84860304 35.06037833 30.49449234 21.1443911 31.39002669 29.68517565 29.76946627 54.34823854 43.44104221 25.22959086 36.36156221 38.3569129 30.29951924 36.26332148 26.61747136 38.01817042 39.18140897 38.18020077 20.14067115 27.07716191 30.38233137 25.52492214 34.90350087 26.47319578 32.66143437 27.52598397 40.38806855 31.28485091 25.35798079 31.80409594 30.27065009 25.31601053 28.82293577 28.63462255 28.49222557 28.15902176 24.21882563 47.58714425 34.7359866 36.88900916 37.15511078 27.333623 35.99503471 27.68341568 27.34880293 51.42951023 24.56889847 31.07992662 32.7147232 23.47717074 46.52637393 42.37846678 31.91252238 33.30094575 26.82392931 21.40730852 32.30265624 30.09745092 32.72741279 29.97964139 25.73344474 30.47905211 29.57118186 31.4556547 36.11747635 41.68276688 32.02505266 62.4668753 36.06726858 31.41817826 40.14297376 29.04720996 23.01374281 29.9258421 25.84670251 26.41052023 25.79370608 31.05109947 17.13152316 17.40223878 51.70809386 37.20550644 35.65409451 31.27533783 29.25925371 30.28948033 22.88577009 27.95979043 32.51631624 37.03463496 36.23021074 33.44615328 34.21365563 36.054833 24.03742823 24.46867081 30.10397902 30.35589813 Glutamic Acid 173.032847 270.0614703 60.84578904 185.692569 39.40068001 223.1325106 70.88789899 123.1398649 80.32303493 130.5829939 93.91258907 142.6173568 80.10490956 252.0753427 95.09949582 77.39788303 74.08070026 218.9362222 256.3985867 148.6233897 172.8350071 340.6262185 117.246286 75.31264296 63.01990276 59.15417182 62.58267371 42.66513923 139.221356 127.2222728 180.9093555 119.450513 159.9405428 124.2975875 146.2704313 159.7569596 210.2827638 70.08444353 107.7280726 105.0801892 157.855324 98.87321122 138.8768078 104.3553006 116.945022 103.3872779 129.498032 130.5481977 78.93366844 56.39145053 65.00546107 48.84696664 150.5062834 77.68069017 164.8316168 80.5629655 189.6438117 38.38780628 147.418543 62.85772566 123.069997 74.82169379 123.9473142 70.37742585 140.415645 101.2967765 32.75873937 127.525601 142.3338709 66.94122365 86.79871511 24.33844636 24.80855924 48.6532227 31.08727481 46.02867178 20.59151231 57.78610938 28.39229703 84.11256809 76.74016404 79.22275817 119.806875 69.66573835 84.96898519 27.10120836 27.19362658 38.9314769 63.53554977 107.1583606 93.59288461 77.46166505 128.4060864 64.75994266 84.98580393 92.65146254 83.97442788 51.59579359 52.77749063 20.94010998 56.30775763 103.7474889 132.6648915 40.72135886 104.9549936 23.32576917 20.72569485 17.00972894 25.60181948 74.72032756 66.68146251 61.75255356 50.54272445 46.74192293 66.43665827 61.82835791 58.72565712 71.21394237 53.45680657 32.04343284 29.36507721 28.07702327 55.56980685 56.26502856 46.94168758 60.33126806 74.01213872 63.94081558 81.87053325 66.69502936 52.4364256 68.32684548 109.6682108 53.39775868 62.80074657 70.47720643 59.11770886 40.60110591 58.66722106 54.14471772 43.12127095 56.56417021 78.74074622 67.66477242 44.97731835 53.90858139 56.28472148 61.62128124 65.95017154 58.64027721 79.18858675 48.34450622 45.14183913 beta-Alanine 2.176855995 2.612914757 2.297286992 2.327899153 2.497165244 2.824373448 3.114745063 3.65484186 3.245912066 2.748336064 2.318255149 2.180750334 1.815505672 1.344398568 3.381345564 2.960673263 1.953239215 2.507164106 2.346471437 4.447482356 2.778331318 2.346887644 2.73216565 2.460866932 2.728659862 2.787579958 2.786868351 2.693301783 2.45079434 3.350155708 3.134089168 2.40949934 2.36270163 1.266241117 1.710868472 3.622989165 4.295395884 3.872669267 3.485530249 1.959720423 2.113142583 5.274694623 3.53228261 2.420980935 2.546268679 1.738650111 1.548049623 1.72414025 3.778300238 4.022475522 1.763208032 1.986562999 3.854516216 3.451559726 2.923709252 2.929891953 3.30401193 2.589415814 2.085835035 2.092615128 2.079816466 3.104349147 4.366729871 2.592335251 3.234894208 4.18951597 4.423031968 2.826960862 3.260332736 3.594458162 3.96073414 3.024348115 3.891482431 2.849231352 3.210236076 3.100357156 2.016351027 2.263786097 2.618782054 2.09034255 3.809908678 2.74182585 2.053606354 1.381124991 1.252261836 2.562226768 3.906905786 2.712795141 3.085319038 2.411279119 4.060319278 2.306638175 2.268868378 2.172941421 2.991281644 1.939866519 1.849354311 2.576667078 1.129670299 1.514810104 1.638484864 2.512563114 1.772460455 5.01028301 1.737772918 2.939759413 2.849183518 2.518891696 1.958701283 3.264729823 2.867229774 3.045825189 2.796059593 2.888882083 2.499802254 3.314989213 2.939172304 2.514936925 2.835952082 1.929926565 2.968455971 2.939653032 4.323605325 3.576541018 4.136161338 3.521906529 2.548325435 2.237865686 1.986663969 1.515297367 1.594561076 3.731600802 6.130510132 1.550817928 1.294983747 3.785031117 3.113280259 4.043145111 2.494678803 3.664147504 3.150514852 1.66210745 2.339124752 1.984622428 1.893171552 2.427317699 2.324000946 1.346224993 1.679416052 2.832868745 2.340584993 2.463431609 3.017730166 Threonine 117.9309837 179.7752977 100.1110282 151.8375406 147.2148257 138.4145345 77.44447516 98.61228866 120.7332862 173.1858113 131.3392923 124.725571 111.153628 161.5932359 140.419033 86.68535386 87.88289137 120.5801253 134.202585 99.63591294 117.2918239 150.3942101 112.4408828 142.6465808 125.0020192 190.3393654 129.2553605 129.7487137 115.4485613 143.1975954 123.2002263 108.4260364 130.0867186 86.82952305 87.35914544 107.7656514 84.67781013 176.4530394 96.24246609 108.8386517 111.111391 133.1952344 93.9650015 114.3723723 133.3699124 82.99245755 90.83441034 108.0658892 100.6448817 128.1206585 101.4022683 113.8569756 106.281092 104.3526825 139.0590807 138.9191549 145.3042196 169.2415683 170.5860793 154.3055291 109.7268095 110.1786855 105.1690629 88.37085338 99.31036537 133.6026138 135.7601744 105.5067003 138.1902465 103.8791918 138.2741079 135.7574402 131.1696925 131.9277175 140.3089078 164.5122226 121.8732726 134.5680225 146.2826323 170.2882667 177.793893 148.579929 104.4352459 128.4457828 139.7505838 122.7065896 153.2556135 106.5557625 140.9730375 125.6805634 137.4224866 90.81234033 93.48380381 113.0465584 154.2354818 115.1778038 104.3120185 124.9988514 117.4091633 141.98113 156.4139162 109.4501435 131.3241047 185.8925712 82.87247051 144.6316129 119.570967 104.0019057 129.951306 163.2875731 130.3853586 172.3344772 159.4347397 162.6201494 152.835779 102.6646701 126.7763866 118.9993466 172.8440547 159.199416 163.9180071 164.8439473 212.4064132 137.0881573 102.6299814 186.4794826 178.8061385 101.6563463 95.26372192 132.7586552 118.059534 107.5224941 172.3377219 118.4667374 119.8319907 127.7091854 109.0413938 148.4835875 127.8320147 136.849028 158.7331898 103.0107679 145.2830818 116.3790594 103.1113784 125.2268137 133.6384678 117.7711973 125.5105159 132.3214328 155.6135586 99.30626937 107.8109621 Alanine 270.2636067 422.7400173 408.8044536 352.9741345 368.9260981 391.2819073 333.3238904 413.2277275 368.2723182 347.8193779 358.7115085 291.5252991 313.4422451 438.4766024 310.5346552 360.4979752 329.9481751 308.4910852 308.912994 260.0826934 357.1243728 333.2730225 324.0542203 324.4761771 330.4035853 439.3790036 422.059565 366.3143749 410.9606101 402.7544742 337.9501475 416.5280816 434.2130122 365.6240138 368.5529098 391.3292075 438.5107636 527.8475863 377.0333435 246.6782101 308.0054671 564.2955424 483.6792186 302.5408464 402.5913756 408.8624049 335.5578923 347.7246493 344.8599457 274.5904473 321.7973114 385.3882007 305.7938573 380.0642221 346.8250737 396.7897081 474.8558852 501.3414104 421.1341995 563.8082252 628.3551661 499.764542 264.8078628 297.4286662 478.1198259 306.9068415 335.5368004 376.9124469 471.0956566 353.0176446 369.784564 320.2563127 393.2003203 505.8297071 387.0956021 382.2772495 369.8959994 332.0754452 302.5294755 401.6261432 461.0752745 431.0333491 373.6418334 450.5800562 468.2451667 462.1574909 442.1613074 413.2171098 375.8417863 405.4205899 590.0627086 298.7343664 448.1595484 405.3933421 447.1288279 517.3086115 430.4632925 406.5866902 280.6156706 421.922807 373.5547605 350.5485954 372.8290513 397.8536241 326.5257929 352.9862843 488.5683786 333.9565508 313.3550293 350.3052652 308.8482319 336.5238981 418.0906044 336.0538657 299.4327887 403.1043083 319.294469 357.7946419 378.0795055 315.8841716 367.6614044 417.2485685 559.0488836 387.1846102 344.35831 418.7033437 454.819997 472.7947696 364.0263618 397.9423521 379.3568634 351.9333274 496.6745507 282.3785216 418.3905535 315.4806695 373.4839113 461.4067743 374.5249104 320.1475842 646.2334871 304.1489116 399.8603863 306.9508219 296.9385221 327.8561773 472.6813707 515.6783926 521.3239508 385.1108516 333.0404196 314.6191927 261.0908694 gamma-Amino-N-butyric-acid 0.076953633 0.056571806 0.045025511 0.080358187 0.075828478 0.103614073 0.086419604 0.075767816 0.099670447 0.085819292 0.028390697 0.04560869 0.050223639 0.083044385 0.059156777 0.084106637 0.081326044 0.050628374 0.081868277 0.080430158 0.053516955 0.082424873 0.08752994 0.079966357 0.079501671 0.046380926 0.072552935 0.081392869 0.117301092 0.074666517 0.111336327 0.084585595 0.106110152 0.088267764 0.088318133 0.098211777 0.123517317 0.071628268 0.052101409 0.044640539 0.047736141 0.084324533 0.068560525 0.04336915 0.062914499 0.054527818 0.097516054 0.068344753 0.051368733 0.045043865 0.072017247 0.068114072 0.077334216 0.086537173 0.061071759 0.06580144 0.07056821 0.042758759 0.042597757 0.054196983 0.077648533 0.05815347 0.117704647 0.08024319 0.044695972 0.050317464 0.038501025 0.062892898 0.047253327 0.066382632 0.03587275 0.057210328 0.075819979 0.054016064 0.046255053 0.043328596 0.036871329 0.061112654 0.064705279 0.086677282 0.072489513 0.084035677 0.047642979 0.093881512 0.075068726 0.162672796 0.121208467 0.142475835 0.112813368 0.097769907 0.120380821 0.091151772 0.138221955 0.100313034 0.122720178 0.104536677 0.060844767 0.124058514 0.077612666 0.052628349 0.100600548 0.12559239 0.117976372 0.131823152 0.144855424 0.076980163 0.073597602 0.109487121 0.090866387 0.108115124 0.088673876 0.082112185 0.073060299 0.129646001 0.134520086 0.131424423 0.153786297 0.121824442 0.15182471 0.108577719 0.122603243 0.101112443 0.146424389 0.129277246 0.112846918 0.155591758 0.095593021 0.153070797 0.178390573 0.103729646 0.087396867 0.102476221 0.126933254 0.165979584 0.169691499 0.170699205 0.193483799 0.111744693 0.06814378 0.08787739 0.112549418 0.093914259 0.087537077 0.166359977 0.180391051 0.09642333 0.135995013 0.136357135 0.136281964 0.089597763 0.086213603 0.100891614 0.123733414 alpha-Aminoadipic-acid 0.346612168 0.385389895 0.198407063 0.872228483 0.451278369 0.551304199 0.356631297 0.793903144 0.676723539 0.50110441 0.874890035 0.784135157 0.564974246 0.712999173 0.745615371 1.316592543 1.119470149 0.35786631 0.324946336 0.790982202 0.537172336 1.097542682 0.665678267 0.477700613 0.279058521 0.749274629 0.732829909 0.792503446 0.500879536 0.488870317 0.858971251 0.429576411 0.296353807 0.293760645 0.435040145 0.418835814 0.505807716 0.323515223 0.279916545 0.297267607 0.251499996 1.090799322 0.807502742 0.497898468 0.663161724 0.551735827 0.549986381 0.783781065 0.351292666 0.518749142 0.473120631 0.501092397 1.29632496 0.887108719 0.590143915 0.676714609 0.452074431 0.500160113 0.401390444 0.740119625 0.633908013 0.73837474 0.517987758 0.563015376 0.613353711 0.364278734 0.425852936 0.429912337 0.580725938 0.740290264 0.614481832 0.552340466 0.780828873 0.555885125 0.587998836 1.073917505 0.70681745 0.379187275 0.690261796 1.663665936 1.539940331 1.938086576 1.038790041 1.022307901 0.8461191 0.995671555 2.21657534 0.899815063 1.076244683 0.725437218 1.05496524 1.211472617 0.658721868 1.047649877 1.993954459 1.313103863 0.871080584 0.787501647 0.541539326 0.565070506 1.508666428 0.809634774 1.0602086 1.083580336 0.556007557 0.409448655 0.255135226 0.576553282 0.452269274 0.460737365 0.574174957 0.824210471 0.737318518 1.104736708 0.692698555 0.651789757 0.620574215 0.527026104 0.519057202 0.245502898 0.098586767 0.29575324 0.466987901 0.836657637 0.478204345 1.858667216 0.915364449 0.734360261 0.667812619 0.846593915 0.644345794 0.794324023 0.960014085 0.782064937 0.63143659 0.722527104 0.932257462 0.485385067 0.807953084 0.693482229 0.5707656 0.70940784 0.625587991 0.420261142 0.345129247 0.885088886 0.785837359 0.864746708 0.758826056 0.473708904 0.57818762 0.479276585 0.421284297 beta-Aminoisobutyric-acid 0.830725037 0.55001609 0.704650961 0.835665879 0.68649368 0.624002452 0.693272339 0.806648678 0.767281868 1.516291436 0.267953572 0.485724325 0.342328375 0.369155471 0.775695623 0.62110635 0.627043479 1.642569121 2.680661387 0.303109694 0.491432059 1.135969165 0.3450832 0.246757544 0.894299368 0.815879247 0.586311317 0.655010461 0.496558488 0.195985514 0.405990179 0.229816501 0.209888684 0.786198009 0.660184602 0.064476129 0.053118989 0.393649786 0.365927205 2.054417487 1.567462133 0.632448564 0.642640616 0.777459452 0.662206394 0.574520046 1.072261013 0.628524663 0.36922614 0.712781046 0.636724004 0.495860778 1.022618712 0.74192096 0.651609845 0.446342055 0.223421993 0.210338227 0.857694771 1.123116037 0.475585603 0.490507592 0.904147459 0.491551751 0.335520066 1.335994468 1.279244659 0.421615159 0.56299097 0.705345381 0.399655517 1.108600108 1.064711438 0.520424762 0.540637325 1.188919542 0.522657282 3.549804189 3.113044447 1.049400037 1.208303396 2.642259053 1.658910835 0.412140346 0.519269726 2.731751237 2.966863571 0.927144694 0.76744146 0.666065552 0.518705099 0.488247402 0.438006487 0.794626871 0.38578298 0.273963194 0.374920626 0.542714349 1.125063221 0.615323338 1.041080269 0.498666963 0.641438665 2.306113653 0.570626358 0.873575294 1.027523419 2.205923771 1.606639323 0.53355935 1.624819749 0.183605778 0.105294743 1.0927845 1.218695524 0.998489485 2.09470249 1.606977278 2.630138747 1.697148839 0.941755481 0.566278808 0.891203755 0.636562807 1.647476455 0.843752938 0.427885174 0.891610462 0.927525234 0.565226552 0.476256261 1.503061812 1.780458183 1.008498739 0.447285085 1.659525164 0.77320463 1.345425197 1.526500198 1.216382896 0.49032694 0.959203072 0.588642711 1.517324256 1.418605263 0.686304074 0.587461672 0.589037841 0.544116575 0.207553995 0.267258099 2.022861499 1.56194195 Proline 175.8126074 196.5948385 199.635519 284.1727709 187.4875092 172.5231553 179.0745009 190.3686865 206.4456893 186.4600099 247.4283328 288.3920993 152.7099415 202.3944219 234.8095143 132.0736477 136.5433757 140.477447 129.5617759 153.7883124 152.0307839 211.6690529 157.7781739 219.1508589 147.3603901 189.2372629 181.7612602 194.770265 202.6777589 231.6276027 174.6646271 274.113818 181.2270143 161.9680122 163.8437754 200.2386706 173.824895 203.0126877 182.9629428 129.363237 135.4823262 172.7399137 139.9002705 187.1469195 230.2935939 149.5337748 158.6563814 153.7357227 136.9503391 143.4737638 168.8395638 219.9003136 169.6943621 190.7655212 164.8234588 208.9591173 231.1304399 183.8278249 149.4320802 203.7390916 176.9960754 181.4991076 120.7795463 131.4776863 237.4560258 165.361867 170.8697176 191.3080078 233.331419 153.8781303 184.3782482 169.1464932 222.864202 214.5113775 233.4840748 228.9862685 237.7893678 188.5585609 183.6390254 190.2956461 213.1458264 252.2103209 233.6719785 297.0753074 271.6847359 226.556259 256.9275536 181.2250562 181.2531346 194.6070135 231.9732652 141.2016204 221.4281301 228.4301018 231.5425448 234.5889185 165.65434 211.1144312 223.424857 247.4599736 239.4359264 202.2787217 261.359523 234.3369402 197.7027391 213.4980994 172.1391853 144.7097452 221.9722055 283.8194084 218.9862522 185.1023707 243.9996318 261.9069183 272.1506195 170.748112 162.7351502 122.7488863 151.6311804 169.1535365 178.8850774 250.2292471 330.713007 204.486022 158.1960054 292.150841 305.4711211 133.5290204 135.1710385 192.7912904 207.6916588 222.4089157 359.9504317 118.5009263 149.0856511 158.4068831 160.8535559 265.6602229 188.0258504 237.889914 364.7062824 144.9003498 198.4355633 198.9058205 177.0241468 186.2168323 222.2499847 222.2295078 226.101843 151.87789 143.2129899 129.0955435 141.2218942 Hydroxylysine 1 0.007473911 0.01678934 0.033715719 0.047283136 0.027910284 0.060320642 0.023724192 0.061578104 0.051367116 0.062330985 0 0.023317088 0.058852812 0.068518679 0.030177276 0.044446595 0.022458038 0.016648844 0.025320721 0.041637054 0.050830116 0.046437061 0.041215687 0.040849959 0.027071531 0.018753464 0.032285753 0.032435902 0.027121287 0.015906875 0.025273335 0.016999192 0.008283933 0.047861144 0.040357442 0.045146117 0.038168559 0.047941032 0.015571602 0.024491985 0.02879271 0.048320467 0.043768631 0.023644139 0.02556805 0.015062129 0.038777953 0.05224598 0.02038383 0.020939845 0.062187517 0.030515162 0.022985426 0.029344129 0.027587692 0.025882802 0.019253385 0.022394905 0.027446202 0.024063142 0.041179018 0.04285944 0.015361044 0.017516219 0.025383354 0.01298291 0.035723759 0.006037843 0.020133433 0.034352395 0.033499128 0.025422534 0.040271202 0.034133261 0.031320551 0.034331277 0.039932779 0.032636167 0.027060044 0.089080032 0.070600006 0.074233663 0.07409187 0.065062413 0.06044735 0.067226001 0.05163918 0.081880669 0.064036825 0.065374902 0.053674644 0.062865134 0.056697412 0.044264716 0.084352145 0.100049142 0.058060986 0.109119966 0.059939281 0.050829977 0.037632974 0.047055749 0.030597575 0.091361928 0.084340687 0.04614732 0.046793809 0.052716155 0.032114345 0.075931976 0.043495945 0.03146239 0.034066236 0.064177847 0.061427303 0.043849813 0.081065271 0.103386225 0.101568183 0.084658877 0.063537642 0.068003688 0.058159107 0.081926546 0.080845423 0.059620867 0.057583138 0.064071822 0.080459373 0.074180664 0.044240521 0.070450026 0.084180641 0.079854525 0.074135179 0.024030088 0.072877128 0.066697527 0.077160523 0.081415422 0.048873213 0.0753576 0.084818811 0.097083633 0.070629101 0.066966833 0.080465175 0.086793157 0.099535992 0.043953353 0.057679997 0.072193908 0.077732161 Hydroxylysine 2 0.403871275 0.571175707 0.843954134 1.571365122 0.879713551 1.255979592 0.693054294 0.850317763 0.793550515 0.721299682 0.634585648 0.677606812 0.810409038 0.939454353 0.6301673 1.255124678 1.009882687 0.468336186 0.429220961 1.251025153 0.886374717 0.694209209 0.56139172 0.487318479 0.640037861 0.574443725 0.639496715 0.532191802 0.578154372 0.470731282 0.521818152 0.443711075 0.458166495 0.726318744 0.66038393 0.923805365 1.027539351 0.389757991 0.284780065 1.129860575 1.473359409 1.707129914 1.830671692 0.567924679 0.623921857 0.564759575 0.725824954 1.238334734 0.848521881 0.968085704 0.878966711 0.964557404 0.793646115 0.676381971 0.750389479 0.68365986 0.513494047 0.598681818 0.510046481 0.42323679 1.388328167 1.432498514 0.564183955 0.632297558 0.74235329 0.41831912 0.58533954 0.394861407 0.470011927 0.681605423 1.318540698 0.730529808 0.71892658 0.607078428 0.640117805 0.74316219 0.920368462 0.88707182 0.899265174 1.903514278 2.020622549 2.24137474 1.276656096 0.77778872 0.693869754 1.010834158 1.318672776 1.24952998 1.052226948 1.018354281 1.098627121 1.030775103 1.255256924 1.095200418 1.724925711 1.370631995 1.121106318 1.863168096 0.730743846 0.730737965 1.082113941 1.285393981 0.855262839 2.505434596 0.978068906 0.390602082 0.364141648 1.094767735 0.910354326 1.613696321 1.37303052 1.035209133 1.022762667 1.936422399 0.921685096 1.806705661 1.753190353 1.262107201 1.014570666 0.627832173 0.547097322 0.923034252 0.492767897 2.130332863 1.587834858 1.481428676 1.115344871 1.106824776 0.960894326 1.03271335 0.810585317 0.597039486 0.989515081 1.088806531 1.012639973 0.46664768 0.910686282 0.889306462 0.905807744 0.614271053 0.67907528 1.222825499 1.231621513 1.230009855 2.289193614 0.595335339 0.767287562 1.585450253 1.50181469 0.60589268 0.582172003 0.475442586 0.422597704 alpha-Amino-N-butyric-acid 16.34165146 22.22600278 8.002292986 13.64543846 13.98244557 12.1162445 12.78965054 22.58738122 21.10677289 39.37702993 12.72223645 24.12154532 12.59738082 16.66215241 14.61006405 23.74312361 18.38500726 20.46029145 19.55999047 13.13844078 13.41982797 19.52845603 14.88528397 16.69541519 11.18773429 19.06402779 30.62829379 19.30323784 8.206781468 13.68038113 21.15712498 17.09334335 14.03580664 11.85381015 11.54225494 12.4684609 9.948247088 13.30399912 9.913139673 23.79330955 11.75755675 29.74434303 20.29331411 14.65226423 12.48386211 17.48017592 29.26577803 21.35206757 11.47411839 15.7886862 17.43470503 10.65861914 27.48081585 16.00546631 23.2224561 21.23428461 16.47563784 21.05432042 20.57779366 16.82010194 16.05760767 19.95763501 22.44111591 15.75644266 19.32551777 29.63672116 26.52940593 14.57728443 20.01897551 16.52892739 13.38095682 28.29240892 25.0052725 10.78853526 9.851940486 53.13215574 18.34193404 7.597499136 12.86316887 25.50478796 29.33426796 24.39330139 11.83595646 11.75133534 14.50176864 15.82094881 22.26630407 16.08608426 13.4620759 10.06200277 17.65555527 19.03782518 6.934346215 17.56947307 24.0378338 15.13252643 13.30038154 14.14071508 22.85996422 27.31709149 29.01306886 17.6305818 15.70915506 20.01607856 14.13498742 11.06581263 13.23589468 29.97917739 15.73811437 13.11907655 24.02674385 21.76301845 19.82698483 14.71022377 14.14994944 12.87396481 19.99499423 12.47404123 22.14041303 32.45172988 12.44981882 13.28320968 20.34867524 25.7048757 36.13901382 64.68746931 29.18525234 19.08595132 19.20307004 24.93333655 17.11880066 27.73148641 24.68250163 22.3496805 12.13658248 22.12867914 15.23810537 16.49859751 24.97993831 50.15238564 27.628286 27.54901596 24.20657416 18.71792391 16.09647314 27.90363488 24.60253714 26.58261833 25.6617633 17.61336475 21.94806553 54.06265259 44.49718369 Ornithine 40.45794566 53.019276 30.09175251 62.92049805 50.16211883 65.26010902 35.18007276 41.77099342 66.36222561 55.62545969 44.72241426 46.78760262 45.43544344 68.0902734 63.89162548 40.2829453 37.532281 47.65544759 42.28885209 50.86454024 46.68705552 63.69710515 39.94365005 49.54026332 57.64355587 77.80469036 40.90227987 51.76888271 52.28439811 46.67289533 49.90674199 48.07011462 41.78572726 35.43002436 40.17877458 46.04411709 39.41767757 39.3782545 30.74715734 29.55126146 36.369698 39.8525578 38.36098094 52.80439952 45.63726994 43.71534756 61.2574126 48.7672622 40.93912678 54.46695205 46.82157923 52.67732317 49.95518571 38.89096385 47.8195067 46.40627122 52.58250997 47.2570534 42.24283223 64.68274507 43.76599852 43.78629262 46.94275627 44.48391308 33.2675505 65.05189288 76.93851515 46.6050561 60.22449242 56.02970049 49.43271472 57.97535927 51.19484268 47.40840435 67.77272396 41.50131407 40.27232601 38.2176147 38.70656568 52.33605379 48.51144832 143.3275291 118.7964126 112.6042639 106.0486506 43.31100696 66.01268172 41.9488332 55.78422348 55.20333297 53.39624815 48.04656851 50.59793368 49.27841576 58.24833398 45.2212831 51.7611332 39.75685164 37.50421274 41.30756004 46.79496305 41.67564723 52.81503655 66.60118802 40.07053503 58.68011137 41.36664296 34.70393625 51.96333397 49.79779242 45.47204211 54.72405944 51.49873636 74.49488924 138.9042782 59.97398361 58.42410668 39.79605174 52.26110221 57.02280005 70.84453777 67.47244485 81.76915819 93.78905379 48.94843259 107.5998544 70.7158817 52.22101897 53.08419071 51.49505283 53.43031916 49.57400994 75.72673184 27.80001992 29.29318652 66.91602275 52.36409358 60.51660129 51.50843198 73.92012606 80.5875544 56.03664702 79.41140168 66.02904123 66.40354639 84.64458191 87.58800352 59.34624323 71.2746219 56.86775139 52.37763075 44.33045778 55.56331598 Cystathionine 1 0.148351304 0.174406536 0.130278054 0.364685152 0.204251264 0.275816728 0.156607034 0.298054634 0.152019465 0.091903698 0.18000305 0.208826109 0.153178303 0.147075202 0.274184827 0.158267743 0.188151272 0.234905452 0.210851818 0.35008487 0.218032883 0.227029637 0.442537922 0.485033264 0.15293189 0.312034498 0.177578739 0.192846099 0.14561909 0.169134072 0.187987955 0.156832057 0.119802995 0.195994529 0.181845301 0.162090132 0.176376387 0.142541862 0.213713378 0.047921834 0.080756003 0.138061813 0.114708977 0.074273218 0.203890949 0.066537663 0.087684622 0.162202925 0.196846168 0.255534785 0.169762719 0.159364933 0.406156046 0.221775485 0.115671261 0.163529663 0.159722083 0.194910137 0.174228777 0.424498812 0.21382898 0.198863813 0.070015281 0.071941365 0.23381654 0.139419953 0.119161303 0.092810196 0.111294053 0.248118763 0.094641969 0.045879817 0.167440567 0.211137733 0.123393278 0.15844435 0.260254653 0.070965421 0.087803867 0.308702398 0.536912942 0.569398272 0.34113816 0.380108561 0.333535561 0.305452762 0.386886588 0.163186179 0.192295739 0.182304109 0.293636905 0.279052931 0.273188536 0.227434109 0.659316587 0.279223853 0.136336312 0.253585334 0.723130655 0.239127183 0.266728409 0.182268969 0.157691578 0.28326409 1.041089651 0.428573809 0.151304791 0.161843839 0.178436838 0.149813811 0.142556975 0.490429396 0.265199615 0.548204955 0.377167131 0.310043795 0.309538672 0.252056319 0.205479927 0.220479724 0.190071716 0.26384817 0.264107801 0.302268517 0.161311183 0.964604382 0.365415452 0.102588318 0.10981282 0.12157862 0.178227264 0.372232772 0.57618246 0.119043655 0.12811341 0.106191301 0.237075127 0.147120794 0.208716082 0.187860961 0.248981131 0.17357557 0.334385118 0.151207103 0.110657628 0.141346882 0.237615601 0.180875457 0.182616103 0.123186551 0.162168556 0.140029561 0.089552345 Cystathionine 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Lysine 155.2794069 181.6825748 139.280839 176.7077701 168.6525175 170.687373 124.9951455 158.4016901 196.8664317 213.8616308 205.8128253 159.8389997 185.6974681 219.2845982 169.6726661 150.7011574 171.9024223 162.3272937 187.1676337 169.3390127 176.812345 187.5704471 202.239806 173.0409325 150.9431441 175.2389372 173.1305484 170.9204257 176.9332694 164.9480628 198.2958946 167.6583668 168.1298077 119.689911 125.2720691 135.5360578 142.8066012 154.7935955 111.3709373 140.1765971 135.0835199 203.1077824 170.4335482 159.3090088 200.2957593 187.0513002 231.6705904 172.7022374 159.2317458 140.5813095 164.714875 191.5276658 160.0109196 177.2232789 179.9407233 214.3139922 188.2221492 210.1185392 187.4063813 219.547519 189.6696218 193.0018944 161.5858527 173.3794648 197.077362 208.6708854 199.6689897 188.2104915 229.1055138 186.849016 174.5453602 202.0437763 198.217453 233.6809843 196.2125736 210.0881501 159.5969811 170.0858154 197.4394927 190.1645749 201.3946876 206.9088843 157.9468694 229.826231 194.0957156 181.0149108 200.0719536 194.1508767 192.8421698 167.4649126 212.4872694 152.4753245 154.9748116 166.8106145 219.0766545 199.5440747 189.7377566 145.1719154 141.4837753 179.6166282 197.1718716 157.3894708 195.6951933 187.9019138 158.2458085 174.2428043 152.9988434 147.2362624 133.7527965 193.6840048 204.5467595 174.3221137 153.777367 179.6283178 157.4983889 149.820241 165.5011558 158.1046513 196.5639887 145.922154 127.6464317 192.5276068 321.8019172 161.0623348 154.942216 214.3015897 179.4425824 231.8546385 216.2243832 182.0776179 169.1342081 171.952417 184.1541701 201.2154546 169.2328687 212.0204574 196.6633299 164.0692402 192.5634037 197.9440067 213.4185831 181.9052594 207.0309248 171.1987403 162.1906529 195.1675187 205.3922438 187.1904978 188.0786488 150.5279116 162.8065161 157.5536966 137.5825164 Cystine 1.68751423 2.303572666 1.332583299 0.231397806 16.20687973 0.602269163 2.197070755 0.956860376 9.261814582 6.947451896 5.069271912 1.395676607 10.22603328 0.438800867 11.90273689 0.541783887 1.140725113 1.087096117 3.777322897 0.153648335 0.555397463 0.193673611 0.346953803 0.767735776 6.08649595 7.807449425 0.334032842 14.97765118 4.553110621 5.77172287 6.088493355 1.183511735 0.868508898 0.38123975 1.078710077 0.606931886 1.114633226 1.490666723 0.456660687 2.349886156 1.486387998 1.009124856 1.601676094 0.185239672 0.647855636 0.662003772 1.216303637 0.819404736 0.575528775 0.890456737 8.822705868 22.8986873 1.141861063 3.83435934 0.600586519 2.135802967 1.658375247 26.42180358 0.296842558 11.81398624 0.913511077 2.689462481 2.638338392 1.959513124 0.817397133 1.682438252 36.44722906 0.719956688 0.744655603 3.372054609 1.755910824 23.04940034 23.60735808 36.20397995 31.00878868 17.80339366 23.38968766 20.76057908 26.93320201 23.02189242 23.80893345 37.17961089 44.97083551 33.9718058 38.03519989 21.29133923 22.44510691 18.90465313 24.29284061 32.24557902 1.777314632 26.44869995 0.666238178 24.43235626 4.265241724 28.45916127 4.117830371 36.48237366 23.60866086 23.89365605 20.92465314 0.453588953 0.421643256 5.439978206 0.631288376 17.65668551 13.82908115 15.03599189 11.57442913 26.77627455 29.46408455 16.48794645 14.99217398 29.8594208 35.19189784 24.42818481 22.08081807 20.37208299 25.11291472 23.0117919 26.66015924 47.66248277 25.05714801 33.42381799 39.0208479 14.06628758 17.22588859 25.74022601 23.49420091 34.44098648 13.77022546 32.78768235 32.29317093 17.51350505 16.7759472 13.90448123 21.97531046 27.62134198 37.29900921 38.54074998 34.76996181 36.23498444 34.62062445 20.18193387 27.0663179 31.37745464 36.65073626 40.68433639 44.71884635 19.73661831 22.14384748 31.31695354 29.62829943 Tyrosine 78.80133965 75.64372072 66.08923969 86.00195421 70.87643862 84.9664446 67.67218443 71.00472274 55.86756813 57.19431176 87.63895953 66.90857938 82.4619319 91.9427071 73.32460159 95.84770489 95.04256777 50.17348175 65.647388 65.55865815 60.06920298 79.19131788 75.46891385 63.81289612 62.76554027 72.51578846 78.82767785 77.90061185 77.03735662 88.33409266 89.42997149 80.67933359 73.94942651 65.19263505 76.14740784 72.7183151 70.25861133 65.16497849 63.2644264 64.34413308 70.69479733 97.45012836 84.22055982 79.86348943 93.80139791 75.41700099 75.0716089 86.68285683 68.83348612 64.28785939 85.2018305 86.33310568 58.78674687 81.97904659 88.08194684 96.44303482 68.60976821 65.57581279 70.96183315 95.87752087 87.07632717 74.73893382 53.22784877 60.62474843 89.10323943 57.72448495 64.48271874 72.17054225 83.83936213 72.88965218 100.8681814 91.2173794 100.1000869 94.88376548 99.72320836 85.00699784 81.41479897 103.789602 104.6263155 66.04856254 78.42354723 91.10705581 92.82225988 106.7659601 73.0422416 95.42297966 123.6797867 92.09886585 82.64869401 83.59286066 105.7154738 72.61549567 53.95391754 66.47170318 75.8541334 79.21929636 96.63179382 84.31016678 64.40544709 62.85007041 83.42648092 58.08559895 58.84782212 61.32129919 50.51688189 63.67891887 58.47344813 68.82467367 58.92622685 82.02821132 70.01371646 67.77142802 81.01845811 83.99746238 84.31078562 52.87872285 74.55743753 70.66792885 80.02621884 57.14187698 61.98273224 61.10675613 92.49949245 96.51253514 82.30262028 121.0078935 101.0843538 71.80597637 66.3957707 76.51711438 73.38964723 50.6872741 49.4501595 38.89705487 49.83109345 56.79298433 76.79634345 67.5944632 65.66150388 51.31165428 85.61701181 80.62502542 82.20103879 57.41529131 57.82605732 75.17001036 93.9660808 98.96189147 104.9196978 55.78110808 67.99064856 53.5876683 42.19574885 Methionine 20.66297715 25.17416188 21.77533736 27.19219132 20.01298194 25.11651683 18.79349198 20.66128886 22.27611157 23.66503922 28.9577168 22.13389885 19.5688935 25.92545288 20.51981637 19.00036019 21.19361631 22.92296948 27.62585979 18.55005219 17.9570573 25.46462405 21.86488555 19.81116693 21.25501768 24.63786805 20.67515102 21.08245853 21.39757712 21.76958533 26.39727587 18.03720204 22.06899455 15.32133724 18.51737705 17.76488573 19.8887297 22.10642482 20.09443417 19.79633599 21.55295302 28.42773764 23.63160438 17.29636834 27.12329877 22.7550559 28.66704744 19.60559401 22.13252003 21.56184336 22.33911518 27.0479803 18.20099492 24.55858645 22.40543043 24.72412505 22.8401102 26.86651712 25.89852617 26.21158604 25.86297636 21.1789186 22.7272564 17.82389469 26.32106181 23.90974266 26.5261309 20.1150635 26.61513225 19.41345543 25.11995385 23.0596169 23.92150165 29.52223976 27.05298043 22.16440445 23.57502028 24.60825577 23.30770061 20.436175 24.99439425 22.20270273 18.55091854 25.07986641 22.91650789 26.30753498 27.01370123 20.45687069 24.53879605 24.14755291 32.7097137 19.83388228 17.78066405 22.98890767 24.40120228 18.98908304 29.0451685 21.62091582 19.65111146 22.44813875 26.73274648 19.81676212 19.61461528 33.07213996 18.62798005 23.58906121 21.83880365 21.25495276 21.10818675 25.02557506 22.40353098 34.2696291 29.10756526 25.63840152 23.81622298 18.32633528 26.05071885 20.31848351 27.10954501 23.63192699 21.48144762 23.13764931 32.19205533 22.53477051 21.21083505 34.45205278 24.6550337 23.75391878 19.52645548 24.45301818 22.55222927 20.76574123 22.60344968 17.66494593 18.13871624 24.08012136 24.48090877 22.53335369 22.51378482 24.11743941 31.79214062 21.82142267 22.30718049 23.44346255 18.9643205 22.05670956 27.93926267 21.4973439 23.26116707 21.64851942 29.45467476 20.53858273 14.61429248 Valine 226.3870029 228.189613 174.1977566 276.065396 199.0296098 257.091357 219.3778068 248.439221 242.1718549 244.9458922 220.6837838 211.4756692 220.8222444 245.0428213 249.3766643 224.320646 243.2540616 173.6632383 194.4120816 260.3810475 224.4196996 240.6917686 246.3924207 224.0446874 184.3360802 251.9456027 262.7372008 229.8775757 194.7714155 189.4371906 226.7437969 185.1698055 156.8997138 188.6255961 227.8235888 206.401776 244.4680962 224.9032729 217.6540568 178.7024128 181.0950552 281.8241576 243.8587558 233.1419524 258.8514384 243.9180578 285.0035702 251.2655757 191.6546847 215.2946899 239.3540915 242.9539917 341.8098213 242.172391 239.9401453 227.7046182 262.4323149 240.0690718 227.5120361 270.9129211 255.128167 277.1175392 272.186708 213.119653 242.8305844 321.7472226 262.5289237 254.0125053 279.6159261 270.0907082 219.0614532 246.9880333 267.8251912 202.4583128 227.7134501 322.216139 270.5563707 201.7735385 219.1813155 290.8737334 323.1804851 303.8563564 262.0700982 259.1680617 254.9668189 239.7055177 263.3753928 266.3340519 254.3401956 211.0104348 241.921753 259.2747212 211.5470985 217.9733639 367.9124923 286.4400157 234.0453913 212.2700429 198.206609 233.1496135 275.505402 217.1619732 224.7411641 282.9202654 217.1290759 233.6012127 159.4560225 225.669182 195.2813061 244.8991792 239.1710918 302.7866848 277.1254696 233.2083624 214.2947182 235.2941217 231.0992291 190.0483402 230.4573791 210.1885341 171.1081885 246.2391042 360.8337238 349.8163321 268.1189544 357.4786812 228.2627415 261.6078564 264.0919872 264.7489887 234.7346874 236.7458733 238.1964044 209.3948479 197.1712243 273.1055695 245.8638725 243.4657588 247.9946635 289.1834852 279.4194337 227.8756923 260.5109775 219.6130149 201.3644216 304.0660016 288.1605792 276.3003232 272.2806587 220.1839334 241.2864418 244.1388721 242.0045215 Isoleucine 60.7700435 74.97174178 54.50057024 83.51309522 48.64265942 64.14517714 49.40432455 74.93812322 59.94041823 69.79498178 57.52827533 56.68146808 52.61139631 62.89126868 66.18679041 62.17301519 60.81342478 50.20468025 66.59172064 82.3211655 60.08487272 73.85787885 62.90208953 55.05902888 45.5118695 65.18192038 71.91284982 63.50384418 63.43334005 56.88172569 60.3401285 42.62415965 49.57120474 42.85314105 56.18041848 49.43612589 60.85822751 58.86623279 65.06451477 43.58286169 56.49558673 82.80751244 68.10818567 66.64723711 88.23820615 65.84712562 85.5286883 63.13092595 56.86037714 60.38143535 69.14480366 71.40084541 102.3431304 71.86781923 76.5299868 67.27762723 64.71263561 73.9898832 67.87308318 76.93470776 77.63527051 72.27418251 65.36973392 49.65798288 79.33265819 82.97934029 79.26703889 64.81850016 81.30327112 79.78961727 71.4724128 61.45404377 76.99780934 59.87526805 76.94477046 92.95044866 75.43631338 56.60888309 59.25944176 71.23341383 90.57434357 80.69233265 64.24412039 71.49497854 71.86063293 69.47165429 74.43501627 71.97135172 73.75187007 68.67441916 74.23036778 61.49432034 58.04792766 69.88075335 100.0691018 73.7796656 66.05701482 52.82071334 55.01961592 61.87448521 76.71466997 53.83573581 62.13971527 92.80678149 56.99794877 68.80208271 54.98378155 58.25742807 54.14178002 76.24328604 78.97782759 89.99076473 89.85008989 79.37146414 57.20295806 61.51464554 60.5284239 56.14677488 64.11397695 75.07259314 48.95662265 73.43642754 101.6581101 98.73028894 84.7171938 115.2624105 75.31860295 72.47541733 74.1305155 85.4964706 76.15318928 70.65092083 76.31526233 69.02273393 55.87825418 75.73249915 80.1189755 83.49744136 80.29327802 98.81881421 85.77467602 69.87706242 78.69600721 69.46598822 60.04084013 97.00783463 94.66673207 80.99302186 81.88737405 64.11716684 86.64171562 94.19363822 74.08904199 allo-Isoleucine 2.095200365 3.367497575 1.548454509 1.775861029 0.967614421 1.160777971 2.902659752 3.671655803 1.810516864 2.003012352 1.782341733 1.650555844 1.504901347 2.071438371 2.196223667 0.963662111 1.029146493 2.055638881 2.380505995 1.024267685 1.077767699 2.538447578 1.707437913 1.757538242 1.347170807 1.486130142 2.547652158 1.995078369 1.983153575 1.508892356 1.761934615 1.498076045 1.399936076 1.483509495 1.579293874 1.784432358 2.378483105 2.666235342 2.348728393 1.463571568 1.699333675 2.467958935 2.741473393 1.727274529 1.484563615 2.176310527 2.055182643 1.990265832 1.741277337 1.835296297 2.148347731 2.171847504 2.306672818 2.228478797 1.446418914 1.114673704 2.160050793 2.137081463 2.173996127 2.377503106 2.213079022 2.490403156 1.443469561 1.230238164 2.527258656 2.788891407 1.877273003 2.167108996 2.57931428 1.414314233 1.812227357 1.850175646 1.76638693 1.802742605 1.422625028 1.826459036 1.180077629 1.330611854 1.163245032 1.97014429 2.028297978 1.15315606 0.915214506 0.786626219 1.048711885 1.561462577 1.147059925 1.864411577 1.943017888 1.723268252 2.008104181 1.942105458 1.4230788 1.332309803 2.044116361 1.694084804 2.032558754 1.432945531 1.177748719 1.937522271 1.29619984 1.715179501 1.618179008 2.756745272 2.352867514 2.352119246 1.007261129 1.415922103 1.706634975 2.210915651 2.631130468 1.562970903 1.227966211 1.152449547 1.220983606 2.049026401 1.533069533 0.867119367 1.131201762 1.822130482 1.682344862 1.634378383 2.121386344 0.882821709 1.02664484 0.285256296 1.025696091 1.000845967 1.297104653 1.754994809 1.962325837 1.202666334 0.459062657 0.581756685 1.127498085 1.790148893 1.697265468 0.588522048 1.052412392 2.788576282 3.461226551 1.258495698 2.318128566 1.253348338 1.22558249 1.06887733 1.810568635 0.94107863 1.319339648 1.708692479 2.180137319 2.737606157 3.032008741 Homocystine 0.272057892 0.211743871 0.283380959 0.246541994 0.255595103 0.270661131 0.302447612 0.259092018 0.250065522 0.230019724 0.353737533 0.229235633 0.280739622 0.184759925 0.270278158 0.225808758 0.234420085 0.268045536 0.275866346 0.256088962 0.209116888 0.235727444 0.244852876 0.235594572 0.267623134 0.26962107 0.231085894 0.223846086 0.33499471 0.226548774 0.268380325 0.223315647 0.258657295 0.236513618 0.25224422 0.258053338 0.370280782 0.289116052 0.29250006 0.334561669 0.346846272 0.350099836 0.364514572 0.344609516 0.336628277 0.377018515 0.363347541 0.36073535 0.320549383 0.339784691 0.331258911 0.420071517 0.326728094 0.327474687 0.33066179 0.324610603 0.319732232 0.354927435 0.292873249 0.366319801 0.383669029 0.374503439 0 0 0.326000972 0.48094494 0.326594343 0.392910548 0.402499502 0.320884393 0.374570657 0.408608031 0.38065495 0.340862879 0.287037243 0.390978983 0.337147768 0.44243869 0.337581495 0.441566064 0.394970552 0.401302413 0.367520613 0.401343581 0.432506706 0.528721793 0.394648384 0.513729694 0.519012725 0.415836923 0.420251217 0.391623061 0.413992983 0.418495793 0.43038865 0.509766434 0.609602351 0.426404412 0.475868498 0.461169168 0.55938285 0.404701811 0.398034054 0.483705418 0.432674861 0.827361144 0.641825005 0.537593925 0.631213473 0.399271511 0.42636837 0.421845567 0.39326704 0.408791967 0.41671362 0.42482403 0.384399271 0.396815129 0.363654641 0.237826289 0.28295266 0.207894631 0.59822978 0.257752177 0.24728303 0.258541102 0.247151016 0.252209718 0.229448589 0.242389739 0.239980887 0.249160437 0.231318513 0.248902999 0.209135995 0.139693695 0.278357531 0.261701727 0.263466738 0.240989662 0.250671172 0.24094254 0.271390327 0.231176746 0.263706872 0.293623692 0.241299997 0.221636466 0.237209483 0.315150454 0.258668754 0.240861535 0.220557445 Leucine 117.8324209 126.8192871 101.2900513 134.5107535 98.39402322 125.8470749 112.7409254 138.9466831 112.8183195 147.2034348 119.313293 110.8319208 107.5124371 109.9567449 126.4640417 108.102956 122.007236 89.22859754 111.9697885 139.1935009 108.2408735 130.0041696 125.1739126 106.8718729 88.83677287 112.0572155 124.6042371 120.0438073 122.3442512 103.654731 118.7837806 93.33551034 89.72425235 83.15635256 105.8150781 94.36195848 117.6227882 112.2381265 115.8799939 88.29722929 94.27187169 151.6098796 139.6210526 117.5348102 148.9121742 119.2250926 145.3828882 119.5617003 101.0137986 101.1066531 132.1458272 142.0166029 175.9057667 133.5724274 129.8455032 123.3145682 126.6811568 128.0990341 117.04422 129.3217312 126.4981857 132.8642001 121.198386 107.1786938 156.1475797 152.5466586 145.9441103 123.913071 151.8078822 138.0223737 130.6922963 116.0679803 138.9477613 122.7276776 127.1327766 158.5112345 134.6300263 96.1346913 109.1550706 135.9571643 154.5022076 136.8933887 123.6846335 131.1011586 127.4557848 129.9826491 131.3438432 131.4282129 131.6916381 122.7325543 138.5861233 119.3210279 131.0256309 125.6095615 178.3021048 153.7706223 118.9577841 106.2430241 105.3020404 105.8571272 148.4957061 104.4015406 118.2609958 147.0182753 109.6383768 129.3041174 90.54090135 106.4111789 101.4946231 136.3333292 151.1144346 166.0344852 169.7311161 127.0249137 115.8185786 123.7885891 127.6512547 117.9030982 122.6442521 125.4316659 112.057912 124.7718874 191.1817071 164.9004996 140.0515383 190.4500177 136.120798 149.5211049 145.9939603 158.0018346 145.2472532 124.51052 123.3277949 135.34401 108.9760263 150.6632296 147.2961026 142.3130354 139.5303053 164.5354044 160.7052711 116.6175219 133.6178929 130.2722647 115.4889577 165.8029768 161.5509941 141.5697732 145.5191514 125.4448805 133.7089158 167.9378354 126.2337194 Phenylalanine 57.21486774 62.41125502 48.50256587 57.20106957 50.77323465 64.75200988 57.90048431 58.67787212 63.1961118 59.19107914 74.41809255 57.30665991 56.27091712 53.28247032 60.70974354 63.15088831 65.41546534 52.1526139 65.3390157 64.55075524 52.6020486 57.67578176 54.78602609 51.00748859 51.94666034 60.65507591 52.52519919 53.80124281 56.52368624 59.00817494 71.89015506 51.44150905 61.96850525 45.75842178 56.06637406 50.27074029 56.57781786 63.49577325 65.49750354 46.26904651 55.11774942 68.88112981 66.21758601 59.12525655 70.04217756 57.92012199 65.94236618 59.91783839 51.95622082 49.8160863 59.36288129 66.98593393 59.90723414 61.54155722 54.75223869 56.87635188 60.35326567 62.36902115 52.03991901 57.84111329 59.85783483 58.5568932 58.91236558 54.22380126 74.67261417 59.89678946 73.48982404 57.73172228 60.69665084 65.78373053 64.48551937 56.28008252 56.2353412 65.07856901 73.34697937 58.04875934 62.90699396 54.32058632 58.60481691 63.12509948 60.53360979 56.98397341 57.05664971 67.0953802 56.40361203 67.28845164 64.80051718 56.08217665 63.68559594 54.31624686 70.00471804 62.49049455 49.6524413 65.45734587 68.96203334 65.45415028 71.58631842 64.94405389 53.46424895 55.30229236 69.27396442 49.57922659 55.95464188 50.97066998 48.33213602 54.58307972 53.89073292 60.1603541 51.08193816 74.6205588 63.14697198 72.0034639 75.40192904 67.1299727 67.21969506 66.26596213 68.99289278 70.4453829 82.42847459 68.91706957 69.8389225 66.23001289 102.9437482 80.64264357 71.26666313 95.3308211 81.48367036 89.05373458 80.32680254 65.12483308 69.05110309 55.92724058 53.69021895 68.2917484 68.58361209 75.08936286 80.63766914 71.1456735 64.53438963 62.75885305 80.95212026 61.54584666 58.2107772 72.23903333 62.88851778 77.30829659 84.63684386 65.17132842 72.14581349 64.20534526 66.97981845 74.05275694 60.84797327 Tryptophan 54.61460144 44.1403939 62.98241624 79.69648123 52.36500002 57.67465822 62.51215352 56.97478266 56.65806768 37.41047918 71.32837658 53.9279923 50.01182454 55.81893398 48.20291309 59.91480085 62.60834111 41.63945288 54.46379059 72.88884794 51.84547554 54.65893653 55.32106897 47.5610089 50.73393549 51.09649619 53.80875725 49.44196352 56.75475569 42.93550872 51.96881789 49.54850237 48.77456733 33.94006302 47.49420301 48.6831387 59.1575255 49.92549136 56.22384865 38.29228577 62.77198207 61.33913929 64.42142558 54.81647283 84.02389195 68.64550875 69.18215949 52.15857325 49.37444537 36.42919204 62.12015147 51.95997058 55.40181899 53.92373966 42.66491994 44.32298276 51.27484653 52.47989482 46.17898274 54.92765755 61.33795316 52.87707085 58.15760624 54.08670029 62.90622971 61.53053213 53.07233959 51.86436632 63.92399221 73.92588221 72.56537625 49.42882661 51.66745583 55.02552103 61.24597113 61.08738518 56.32645359 64.84162475 52.16354958 56.60096187 53.78514472 52.38651391 52.15195731 59.02886771 54.75947268 85.34567485 77.149745 54.60507237 73.29702903 66.01593519 54.81113321 47.6231913 48.06220234 53.81855138 77.37754175 50.9419825 57.25302433 55.83236886 49.69648517 59.87430878 68.38494276 57.29043207 53.15622087 71.90540903 42.70960691 69.00401999 63.52233696 54.43989933 54.45879079 63.10734021 57.27339791 55.93748998 53.96607914 61.17387195 57.12235036 54.37466324 51.06326846 59.90182519 65.64221779 48.41948824 44.45015487 50.63300917 75.71752716 66.75154643 49.00725068 73.49437143 70.57420197 56.34808368 57.68488898 66.64719779 54.39866989 60.07252254 53.13441374 43.53807298 65.23166526 68.20276374 70.79829027 61.79951454 55.54619211 51.24912715 62.14985011 51.31216752 52.65464209 51.57513735 53.67449557 66.55938265 78.78268123 71.74571849 70.84895824 57.20741257 56.33586493 43.62749716 41.8566954 MS_METABOLITE_DATA_END #METABOLITES METABOLITES_START metabolite_name Histidine Hydroxyproline 1-Methylhistidine 3-Methylhistidine Asparagine Phosphoethanolamine Arginine Carnosine Taurine Anserine Serine Glutamine Ethanolamine Glycine Aspartic Acid Sarcosine Citrulline Glutamic Acid beta-Alanine Threonine Alanine gamma-Amino-N-butyric-acid alpha-Aminoadipic-acid beta-Aminoisobutyric-acid Proline Hydroxylysine 1 Hydroxylysine 2 alpha-Amino-N-butyric-acid Ornithine Cystathionine 1 Cystathionine 2 Lysine Cystine Tyrosine Methionine Valine Isoleucine allo-Isoleucine Homocystine Leucine Phenylalanine Tryptophan METABOLITES_END #END