#METABOLOMICS WORKBENCH Andre_Gollowitzer_20210401_063729 DATATRACK_ID:2552 STUDY_ID:ST001740 ANALYSIS_ID:AN002833
VERSION                          	1
CREATED_ON                       	06-03-2022
#PROJECT
PR:PROJECT_TITLE                 	Regulation of stress signalling by SCD1-derived phosphatidylinositols
PR:PROJECT_TYPE                  	Targeted lipidomics
PR:PROJECT_SUMMARY               	Cytotoxic stress activates stress-activated kinases, initiates adaptive
PR:PROJECT_SUMMARY               	mechanisms, including the unfolded protein response (UPR) and autophagy, and
PR:PROJECT_SUMMARY               	induces programmed cell death. Fatty acid unsaturation, controlled by
PR:PROJECT_SUMMARY               	stearoyl-CoA desaturase (SCD)1, prevents cytotoxic stress but the mechanisms are
PR:PROJECT_SUMMARY               	diffuse. We found that 1,2-dioleoyl-sn-glycero-3-phospho-(1’-myo-inositol)
PR:PROJECT_SUMMARY               	[PI(18:1/18:1)] is a SCD1-derived signaling lipid, which inhibits p38
PR:PROJECT_SUMMARY               	mitogen-activated protein kinase (MAPK) activation, counteracts UPR, autophagy
PR:PROJECT_SUMMARY               	and apoptosis induction, and maintains cell morphology and proliferation. SCD1
PR:PROJECT_SUMMARY               	expression and the cellular PI(18:1/18:1) proportion decrease during the onset
PR:PROJECT_SUMMARY               	of cell death, thereby activating stress signaling. This counter-regulation
PR:PROJECT_SUMMARY               	applies to mechanistically diverse death-inducing conditions and occurs in
PR:PROJECT_SUMMARY               	tissues of Scd1-defective mice.
PR:INSTITUTE                     	University of Innsbruck
PR:DEPARTMENT                    	Michael Popp Institute
PR:LAST_NAME                     	Koeberle
PR:FIRST_NAME                    	Andreas
PR:ADDRESS                       	Mitterweg 24, Innsbruck, Tyrol, 6020, Austria
PR:EMAIL                         	andreas.koeberle@uibk.ac.at
PR:PHONE                         	+43 512 507 57903
PR:FUNDING_SOURCE                	German Research Council (GRK 1715 and KO 4589/4-1), Phospholipid Research Center
PR:FUNDING_SOURCE                	Heidelberg (AKO-2019-070/2-1 and AKO-2015-037/1-1), University of Jena
PR:FUNDING_SOURCE                	(DRM/2013-05 and 2.7-05), Free State of Thuringia (41-5507-2016) and Leibniz
PR:FUNDING_SOURCE                	ScienceCampus InfectoOptics (SAS-2015-HKI-LWC).
PR:PUBLICATIONS                  	PI(18:1/18:1) is a SCD1-derived lipokine that limits stress signaling. Thürmer
PR:PUBLICATIONS                  	M, Gollowitzer A, Pein H, Neukirch K, Gelmez E, Waltl L, Wielsch N, Winkler R,
PR:PUBLICATIONS                  	Löser K, Grander J, Hotze M, Harder S, Döding A, Meßner M, Troisi F, Ardelt
PR:PUBLICATIONS                  	M, Schlüter H, Pachmayr J, Gutiérrez-Gutiérrez Ó, Rudolph KL, Thedieck K,
PR:PUBLICATIONS                  	Schulze-Späte U, González-Estévez C, Kosan C, Svatoš A, Kwiatkowski M,
PR:PUBLICATIONS                  	Koeberle A. Nat Commun. 2022 May 27;13(1):2982. doi: 10.1038/s41467-022-30374-9.
PR:DOI                           	http://dx.doi.org/10.21228/M8Q39V
#STUDY
ST:STUDY_TITLE                   	Timecourse of NIH-3T3 cells treated with apoptotic inducers
ST:STUDY_TYPE                    	Targeted lipidomics
ST:STUDY_SUMMARY                 	Time-dependent changes of phosphatidylinositol profiles in mouse NIH-3T3
ST:STUDY_SUMMARY                 	fibroblasts treated with mechanistically diverse apoptotic inducers.
ST:INSTITUTE                     	University of Innsbruck
ST:DEPARTMENT                    	Michael Popp Institute
ST:LAST_NAME                     	Koeberle
ST:FIRST_NAME                    	Andreas
ST:ADDRESS                       	Mitterweg 24, Innsbruck, Tyrol, 6020, Austria
ST:EMAIL                         	andreas.koeberle@uibk.ac.at
ST:PHONE                         	+43 512 507 57903
ST:SUBMIT_DATE                   	2021-04-01
#SUBJECT
SU:SUBJECT_TYPE                  	Cultured cells
SU:SUBJECT_SPECIES               	Mus musculus
SU:TAXONOMY_ID                   	10090
#SUBJECT_SAMPLE_FACTORS:         	SUBJECT(optional)[tab]SAMPLE[tab]FACTORS(NAME:VALUE pairs separated by |)[tab]Additional sample data
SUBJECT_SAMPLE_FACTORS           	-	HP_140211_AP4_10m_1h_#45 - 5	hours:0.17 | treatment:CHX | concentration:20 µg/ml	RAW_FILE_NAME=HP_140211_AP4_10m_1h
SUBJECT_SAMPLE_FACTORS           	-	HP_140214_AP4und5_48h_10min_#10 - 5	hours:0.17 | treatment:CHX | concentration:20 µg/ml	RAW_FILE_NAME=HP_140214_AP4und5_48h_10min
SUBJECT_SAMPLE_FACTORS           	-	HP_140311_AP6_10min_#45 - 5	hours:0.17 | treatment:CHX | concentration:20 µg/ml	RAW_FILE_NAME=HP_140311_AP6_10min
SUBJECT_SAMPLE_FACTORS           	-	HP_140211_AP4_10m_1h_#46 - 6	hours:0.17 | treatment:ETO | concentration:10 µM	RAW_FILE_NAME=HP_140211_AP4_10m_1h
SUBJECT_SAMPLE_FACTORS           	-	HP_140214_AP4und5_48h_10min_#11 - 6	hours:0.17 | treatment:ETO | concentration:10 µM	RAW_FILE_NAME=HP_140214_AP4und5_48h_10min
SUBJECT_SAMPLE_FACTORS           	-	HP_140311_AP6_10min_#46 - 6	hours:0.17 | treatment:ETO | concentration:10 µM	RAW_FILE_NAME=HP_140311_AP6_10min
SUBJECT_SAMPLE_FACTORS           	-	HP_140211_AP4_10m_1h_#50 - 10	hours:0.17 | treatment:MC | concentration:10 µM	RAW_FILE_NAME=HP_140211_AP4_10m_1h
SUBJECT_SAMPLE_FACTORS           	-	HP_140214_AP4und5_48h_10min_#15 - 10	hours:0.17 | treatment:MC | concentration:10 µM	RAW_FILE_NAME=HP_140214_AP4und5_48h_10min
SUBJECT_SAMPLE_FACTORS           	-	HP_140311_AP6_10min_#50 - 10	hours:0.17 | treatment:MC | concentration:10 µM	RAW_FILE_NAME=HP_140311_AP6_10min
SUBJECT_SAMPLE_FACTORS           	-	HP_140211_AP4_10m_1h_#49 - 9	hours:0.17 | treatment:Serum | concentration:-	RAW_FILE_NAME=HP_140211_AP4_10m_1h
SUBJECT_SAMPLE_FACTORS           	-	HP_140214_AP4und5_48h_10min_#14 - 9	hours:0.17 | treatment:Serum | concentration:-	RAW_FILE_NAME=HP_140214_AP4und5_48h_10min
SUBJECT_SAMPLE_FACTORS           	-	HP_140311_AP6_10min_#49 - 9	hours:0.17 | treatment:Serum | concentration:-	RAW_FILE_NAME=HP_140311_AP6_10min
SUBJECT_SAMPLE_FACTORS           	-	HP_140211_AP4_10m_1h_#44 - 4	hours:0.17 | treatment:STS | concentration:0.3 µM	RAW_FILE_NAME=HP_140211_AP4_10m_1h
SUBJECT_SAMPLE_FACTORS           	-	HP_140214_AP4und5_48h_10min_#9 - 4	hours:0.17 | treatment:STS | concentration:0.3 µM	RAW_FILE_NAME=HP_140214_AP4und5_48h_10min
SUBJECT_SAMPLE_FACTORS           	-	HP_140311_AP6_10min_#44 - 4	hours:0.17 | treatment:STS | concentration:0.3 µM	RAW_FILE_NAME=HP_140311_AP6_10min
SUBJECT_SAMPLE_FACTORS           	-	HP_140211_AP4_10m_1h_#43 - 3	hours:0.17 | treatment:TNFα | concentration:10 ng/ml	RAW_FILE_NAME=HP_140211_AP4_10m_1h
SUBJECT_SAMPLE_FACTORS           	-	HP_140214_AP4und5_48h_10min_#8 - 3	hours:0.17 | treatment:TNFα | concentration:10 ng/ml	RAW_FILE_NAME=HP_140214_AP4und5_48h_10min
SUBJECT_SAMPLE_FACTORS           	-	HP_140311_AP6_10min_#43 - 3	hours:0.17 | treatment:TNFα | concentration:10 ng/ml	RAW_FILE_NAME=HP_140311_AP6_10min
SUBJECT_SAMPLE_FACTORS           	-	HP_140211_AP4_10m_1h_#47 - 7	hours:0.17 | treatment:TPG | concentration:2 µM	RAW_FILE_NAME=HP_140211_AP4_10m_1h
SUBJECT_SAMPLE_FACTORS           	-	HP_140214_AP4und5_48h_10min_#12 - 7	hours:0.17 | treatment:TPG | concentration:2 µM	RAW_FILE_NAME=HP_140214_AP4und5_48h_10min
SUBJECT_SAMPLE_FACTORS           	-	HP_140311_AP6_10min_#47 - 7	hours:0.17 | treatment:TPG | concentration:2 µM	RAW_FILE_NAME=HP_140311_AP6_10min
SUBJECT_SAMPLE_FACTORS           	-	HP_140211_AP4_10m_1h_#48 - 8	hours:0.17 | treatment:VAL | concentration:10 µM	RAW_FILE_NAME=HP_140211_AP4_10m_1h
SUBJECT_SAMPLE_FACTORS           	-	HP_140214_AP4und5_48h_10min_#13 - 8	hours:0.17 | treatment:VAL | concentration:10 µM	RAW_FILE_NAME=HP_140214_AP4und5_48h_10min
SUBJECT_SAMPLE_FACTORS           	-	HP_140311_AP6_10min_#48 - 8	hours:0.17 | treatment:VAL | concentration:10 µM	RAW_FILE_NAME=HP_140311_AP6_10min
SUBJECT_SAMPLE_FACTORS           	-	HP_140211_AP4_10m_1h_#42 - 2	hours:0.17 | treatment:vehicle (DMSO) | concentration:-	RAW_FILE_NAME=HP_140211_AP4_10m_1h
SUBJECT_SAMPLE_FACTORS           	-	HP_140211_AP4_10m_1h_#52 - 12	hours:0.17 | treatment:vehicle (DMSO) | concentration:-	RAW_FILE_NAME=HP_140211_AP4_10m_1h
SUBJECT_SAMPLE_FACTORS           	-	HP_140214_AP4und5_48h_10min_#17 - 12	hours:0.17 | treatment:vehicle (DMSO) | concentration:-	RAW_FILE_NAME=HP_140214_AP4und5_48h_10min
SUBJECT_SAMPLE_FACTORS           	-	HP_140214_AP4und5_48h_10min_#7 - 2	hours:0.17 | treatment:vehicle (DMSO) | concentration:-	RAW_FILE_NAME=HP_140214_AP4und5_48h_10min
SUBJECT_SAMPLE_FACTORS           	-	HP_140311_AP6_10min_#42 - 2	hours:0.17 | treatment:vehicle (DMSO) | concentration:-	RAW_FILE_NAME=HP_140311_AP6_10min
SUBJECT_SAMPLE_FACTORS           	-	HP_140311_AP6_10min_#52 - 12	hours:0.17 | treatment:vehicle (DMSO) | concentration:-	RAW_FILE_NAME=HP_140311_AP6_10min
SUBJECT_SAMPLE_FACTORS           	-	HP_140211_AP4_10min_1h_#10 - 5	hours:1 | treatment:CHX | concentration:20 µg/ml	RAW_FILE_NAME=HP_140211_AP4_10min_1h
SUBJECT_SAMPLE_FACTORS           	-	HP_140217_AP5_1h_6h_#45 - 5	hours:1 | treatment:CHX | concentration:20 µg/ml	RAW_FILE_NAME=HP_140217_AP5_1h_6h
SUBJECT_SAMPLE_FACTORS           	-	HP_140312_AP6_1h_#45 - 5	hours:1 | treatment:CHX | concentration:20 µg/ml	RAW_FILE_NAME=HP_140312_AP6_1h
SUBJECT_SAMPLE_FACTORS           	-	HP_140211_AP4_10min_1h_#11 - 6	hours:1 | treatment:ETO | concentration:10 µM	RAW_FILE_NAME=HP_140211_AP4_10min_1h
SUBJECT_SAMPLE_FACTORS           	-	HP_140217_AP5_1h_6h_#46 - 6	hours:1 | treatment:ETO | concentration:10 µM	RAW_FILE_NAME=HP_140217_AP5_1h_6h
SUBJECT_SAMPLE_FACTORS           	-	HP_140312_AP6_1h_#46 - 6	hours:1 | treatment:ETO | concentration:10 µM	RAW_FILE_NAME=HP_140312_AP6_1h
SUBJECT_SAMPLE_FACTORS           	-	HP_140211_AP4_10min_1h_#15 - 10	hours:1 | treatment:MC | concentration:10 µM	RAW_FILE_NAME=HP_140211_AP4_10min_1h
SUBJECT_SAMPLE_FACTORS           	-	HP_140217_AP5_1h_6h_#50 - 10	hours:1 | treatment:MC | concentration:10 µM	RAW_FILE_NAME=HP_140217_AP5_1h_6h
SUBJECT_SAMPLE_FACTORS           	-	HP_140312_AP6_1h_#50 - 10	hours:1 | treatment:MC | concentration:10 µM	RAW_FILE_NAME=HP_140312_AP6_1h
SUBJECT_SAMPLE_FACTORS           	-	HP_140211_AP4_10min_1h_#14 - 9	hours:1 | treatment:Serum | concentration:-	RAW_FILE_NAME=HP_140211_AP4_10min_1h
SUBJECT_SAMPLE_FACTORS           	-	HP_140217_AP5_1h_6h_#49 - 9	hours:1 | treatment:Serum | concentration:-	RAW_FILE_NAME=HP_140217_AP5_1h_6h
SUBJECT_SAMPLE_FACTORS           	-	HP_140312_AP6_1h_#49 - 9	hours:1 | treatment:Serum | concentration:-	RAW_FILE_NAME=HP_140312_AP6_1h
SUBJECT_SAMPLE_FACTORS           	-	HP_140211_AP4_10min_1h_#9 - 4	hours:1 | treatment:STS | concentration:0.3 µM	RAW_FILE_NAME=HP_140211_AP4_10min_1h
SUBJECT_SAMPLE_FACTORS           	-	HP_140217_AP5_1h_6h_#44 - 4	hours:1 | treatment:STS | concentration:0.3 µM	RAW_FILE_NAME=HP_140217_AP5_1h_6h
SUBJECT_SAMPLE_FACTORS           	-	HP_140312_AP6_1h_#44 - 4	hours:1 | treatment:STS | concentration:0.3 µM	RAW_FILE_NAME=HP_140312_AP6_1h
SUBJECT_SAMPLE_FACTORS           	-	HP_140211_AP4_10min_1h_#8 - 3	hours:1 | treatment:TNFα | concentration:10 ng/ml	RAW_FILE_NAME=HP_140211_AP4_10min_1h
SUBJECT_SAMPLE_FACTORS           	-	HP_140217_AP5_1h_6h_#43 - 3	hours:1 | treatment:TNFα | concentration:10 ng/ml	RAW_FILE_NAME=HP_140217_AP5_1h_6h
SUBJECT_SAMPLE_FACTORS           	-	HP_140312_AP6_1h_#43 - 3	hours:1 | treatment:TNFα | concentration:10 ng/ml	RAW_FILE_NAME=HP_140312_AP6_1h
SUBJECT_SAMPLE_FACTORS           	-	HP_140211_AP4_10min_1h_#12 - 7	hours:1 | treatment:TPG | concentration:2 µM	RAW_FILE_NAME=HP_140211_AP4_10min_1h
SUBJECT_SAMPLE_FACTORS           	-	HP_140217_AP5_1h_6h_#47 - 7	hours:1 | treatment:TPG | concentration:2 µM	RAW_FILE_NAME=HP_140217_AP5_1h_6h
SUBJECT_SAMPLE_FACTORS           	-	HP_140312_AP6_1h_#47 - 7	hours:1 | treatment:TPG | concentration:2 µM	RAW_FILE_NAME=HP_140312_AP6_1h
SUBJECT_SAMPLE_FACTORS           	-	HP_140211_AP4_10min_1h_#13 - 8	hours:1 | treatment:VAL | concentration:10 µM	RAW_FILE_NAME=HP_140211_AP4_10min_1h
SUBJECT_SAMPLE_FACTORS           	-	HP_140217_AP5_1h_6h_#48 - 8	hours:1 | treatment:VAL | concentration:10 µM	RAW_FILE_NAME=HP_140217_AP5_1h_6h
SUBJECT_SAMPLE_FACTORS           	-	HP_140312_AP6_1h_#48 - 8	hours:1 | treatment:VAL | concentration:10 µM	RAW_FILE_NAME=HP_140312_AP6_1h
SUBJECT_SAMPLE_FACTORS           	-	HP_140211_AP4_10min_1h_#17 - 12	hours:1 | treatment:vehicle (DMSO) | concentration:-	RAW_FILE_NAME=HP_140211_AP4_10min_1h
SUBJECT_SAMPLE_FACTORS           	-	HP_140211_AP4_10min_1h_#7 - 2	hours:1 | treatment:vehicle (DMSO) | concentration:-	RAW_FILE_NAME=HP_140211_AP4_10min_1h
SUBJECT_SAMPLE_FACTORS           	-	HP_140217_AP5_1h_6h_#42 - 2	hours:1 | treatment:vehicle (DMSO) | concentration:-	RAW_FILE_NAME=HP_140217_AP5_1h_6h
SUBJECT_SAMPLE_FACTORS           	-	HP_140217_AP5_1h_6h_#52 - 12	hours:1 | treatment:vehicle (DMSO) | concentration:-	RAW_FILE_NAME=HP_140217_AP5_1h_6h
SUBJECT_SAMPLE_FACTORS           	-	HP_140312_AP6_1h_#42 - 2	hours:1 | treatment:vehicle (DMSO) | concentration:-	RAW_FILE_NAME=HP_140312_AP6_1h
SUBJECT_SAMPLE_FACTORS           	-	HP_140312_AP6_1h_#52 - 12	hours:1 | treatment:vehicle (DMSO) | concentration:-	RAW_FILE_NAME=HP_140312_AP6_1h
SUBJECT_SAMPLE_FACTORS           	-	HP_140213_AP4_6h_24_restart_#30 - 5	hours:24 | treatment:CHX | concentration:20 µg/ml	RAW_FILE_NAME=HP_140213_AP4_6h_24_restart
SUBJECT_SAMPLE_FACTORS           	-	HP_140227_AP5_24h_48h_#45 - 5	hours:24 | treatment:CHX | concentration:20 µg/ml	RAW_FILE_NAME=HP_140227_AP5_24h_48h
SUBJECT_SAMPLE_FACTORS           	-	HP_140314_AP6_24h_#19 - 5	hours:24 | treatment:CHX | concentration:20 µg/ml	RAW_FILE_NAME=HP_140314_AP6_24h
SUBJECT_SAMPLE_FACTORS           	-	HP_140213_AP4_6h_24_restart_#31 - 6	hours:24 | treatment:ETO | concentration:10 µM	RAW_FILE_NAME=HP_140213_AP4_6h_24_restart
SUBJECT_SAMPLE_FACTORS           	-	HP_140227_AP5_24h_48h_#46 - 6	hours:24 | treatment:ETO | concentration:10 µM	RAW_FILE_NAME=HP_140227_AP5_24h_48h
SUBJECT_SAMPLE_FACTORS           	-	HP_140314_AP6_24h_#20 - 6	hours:24 | treatment:ETO | concentration:10 µM	RAW_FILE_NAME=HP_140314_AP6_24h
SUBJECT_SAMPLE_FACTORS           	-	HP_140213_AP4_6h_24_restart_#35 - 10	hours:24 | treatment:MC | concentration:10 µM	RAW_FILE_NAME=HP_140213_AP4_6h_24_restart
SUBJECT_SAMPLE_FACTORS           	-	HP_140227_AP5_24h_48h_#50 - 10	hours:24 | treatment:MC | concentration:10 µM	RAW_FILE_NAME=HP_140227_AP5_24h_48h
SUBJECT_SAMPLE_FACTORS           	-	HP_140314_AP6_24h_#24 - 10	hours:24 | treatment:MC | concentration:10 µM	RAW_FILE_NAME=HP_140314_AP6_24h
SUBJECT_SAMPLE_FACTORS           	-	HP_140213_AP4_6h_24_restart_#34 - 9	hours:24 | treatment:Serum | concentration:-	RAW_FILE_NAME=HP_140213_AP4_6h_24_restart
SUBJECT_SAMPLE_FACTORS           	-	HP_140227_AP5_24h_48h_#49 - 9	hours:24 | treatment:Serum | concentration:-	RAW_FILE_NAME=HP_140227_AP5_24h_48h
SUBJECT_SAMPLE_FACTORS           	-	HP_140314_AP6_24h_#23 - 9	hours:24 | treatment:Serum | concentration:-	RAW_FILE_NAME=HP_140314_AP6_24h
SUBJECT_SAMPLE_FACTORS           	-	HP_140213_AP4_6h_24_restart_#29 - 4	hours:24 | treatment:STS | concentration:0.3 µM	RAW_FILE_NAME=HP_140213_AP4_6h_24_restart
SUBJECT_SAMPLE_FACTORS           	-	HP_140227_AP5_24h_48h_#44 - 4	hours:24 | treatment:STS | concentration:0.3 µM	RAW_FILE_NAME=HP_140227_AP5_24h_48h
SUBJECT_SAMPLE_FACTORS           	-	HP_140314_AP6_24h_#18 - 4	hours:24 | treatment:STS | concentration:0.3 µM	RAW_FILE_NAME=HP_140314_AP6_24h
SUBJECT_SAMPLE_FACTORS           	-	HP_140213_AP4_6h_24_restart_#28 - 3	hours:24 | treatment:TNFα | concentration:10 ng/ml	RAW_FILE_NAME=HP_140213_AP4_6h_24_restart
SUBJECT_SAMPLE_FACTORS           	-	HP_140227_AP5_24h_48h_#43 - 3	hours:24 | treatment:TNFα | concentration:10 ng/ml	RAW_FILE_NAME=HP_140227_AP5_24h_48h
SUBJECT_SAMPLE_FACTORS           	-	HP_140314_AP6_24h_#17 - 3	hours:24 | treatment:TNFα | concentration:10 ng/ml	RAW_FILE_NAME=HP_140314_AP6_24h
SUBJECT_SAMPLE_FACTORS           	-	HP_140213_AP4_6h_24_restart_#32 - 7	hours:24 | treatment:TPG | concentration:2 µM	RAW_FILE_NAME=HP_140213_AP4_6h_24_restart
SUBJECT_SAMPLE_FACTORS           	-	HP_140227_AP5_24h_48h_#47 - 7	hours:24 | treatment:TPG | concentration:2 µM	RAW_FILE_NAME=HP_140227_AP5_24h_48h
SUBJECT_SAMPLE_FACTORS           	-	HP_140314_AP6_24h_#21 - 7	hours:24 | treatment:TPG | concentration:2 µM	RAW_FILE_NAME=HP_140314_AP6_24h
SUBJECT_SAMPLE_FACTORS           	-	HP_140213_AP4_6h_24_restart_#33 - 8	hours:24 | treatment:VAL | concentration:10 µM	RAW_FILE_NAME=HP_140213_AP4_6h_24_restart
SUBJECT_SAMPLE_FACTORS           	-	HP_140227_AP5_24h_48h_#48 - 8	hours:24 | treatment:VAL | concentration:10 µM	RAW_FILE_NAME=HP_140227_AP5_24h_48h
SUBJECT_SAMPLE_FACTORS           	-	HP_140314_AP6_24h_#22 - 8	hours:24 | treatment:VAL | concentration:10 µM	RAW_FILE_NAME=HP_140314_AP6_24h
SUBJECT_SAMPLE_FACTORS           	-	HP_140213_AP4_6h_24_restart_#27 - 2	hours:24 | treatment:vehicle (DMSO) | concentration:-	RAW_FILE_NAME=HP_140213_AP4_6h_24_restart
SUBJECT_SAMPLE_FACTORS           	-	HP_140213_AP4_6h_24_restart_#37 - 12	hours:24 | treatment:vehicle (DMSO) | concentration:-	RAW_FILE_NAME=HP_140213_AP4_6h_24_restart
SUBJECT_SAMPLE_FACTORS           	-	HP_140227_AP5_24h_48h_#42 - 2	hours:24 | treatment:vehicle (DMSO) | concentration:-	RAW_FILE_NAME=HP_140227_AP5_24h_48h
SUBJECT_SAMPLE_FACTORS           	-	HP_140227_AP5_24h_48h_#52 - 12	hours:24 | treatment:vehicle (DMSO) | concentration:-	RAW_FILE_NAME=HP_140227_AP5_24h_48h
SUBJECT_SAMPLE_FACTORS           	-	HP_140314_AP6_24h_#16 - 2	hours:24 | treatment:vehicle (DMSO) | concentration:-	RAW_FILE_NAME=HP_140314_AP6_24h
SUBJECT_SAMPLE_FACTORS           	-	HP_140314_AP6_24h_#26 - 12	hours:24 | treatment:vehicle (DMSO) | concentration:-	RAW_FILE_NAME=HP_140314_AP6_24h
SUBJECT_SAMPLE_FACTORS           	-	HP_140214_AP4and5_48h_10min_#45 - 5	hours:48 | treatment:CHX | concentration:20 µg/ml	RAW_FILE_NAME=HP_140214_AP4and5_48h_10min
SUBJECT_SAMPLE_FACTORS           	-	HP_140228_AP5_24h_48h_#19 - 5	hours:48 | treatment:CHX | concentration:20 µg/ml	RAW_FILE_NAME=HP_140228_AP5_24h_48h
SUBJECT_SAMPLE_FACTORS           	-	HP_140321_Betti_AP6_48h_#58 - 5	hours:48 | treatment:CHX | concentration:20 µg/ml	RAW_FILE_NAME=HP_140321_Betti_AP6_48h
SUBJECT_SAMPLE_FACTORS           	-	HP_140214_AP4and5_48h_10min_#46 - 6	hours:48 | treatment:ETO | concentration:10 µM	RAW_FILE_NAME=HP_140214_AP4and5_48h_10min
SUBJECT_SAMPLE_FACTORS           	-	HP_140228_AP5_24h_48h_#20 - 6	hours:48 | treatment:ETO | concentration:10 µM	RAW_FILE_NAME=HP_140228_AP5_24h_48h
SUBJECT_SAMPLE_FACTORS           	-	HP_140321_Betti_AP6_48h_#59 - 6	hours:48 | treatment:ETO | concentration:10 µM	RAW_FILE_NAME=HP_140321_Betti_AP6_48h
SUBJECT_SAMPLE_FACTORS           	-	HP_140214_AP4and5_48h_10min_#50 - 10	hours:48 | treatment:MC | concentration:10 µM	RAW_FILE_NAME=HP_140214_AP4and5_48h_10min
SUBJECT_SAMPLE_FACTORS           	-	HP_140228_AP5_24h_48h_#24 - 10	hours:48 | treatment:MC | concentration:10 µM	RAW_FILE_NAME=HP_140228_AP5_24h_48h
SUBJECT_SAMPLE_FACTORS           	-	HP_140321_Betti_AP6_48h_#63 - 10	hours:48 | treatment:MC | concentration:10 µM	RAW_FILE_NAME=HP_140321_Betti_AP6_48h
SUBJECT_SAMPLE_FACTORS           	-	HP_140214_AP4and5_48h_10min_#49 - 9	hours:48 | treatment:Serum | concentration:-	RAW_FILE_NAME=HP_140214_AP4and5_48h_10min
SUBJECT_SAMPLE_FACTORS           	-	HP_140228_AP5_24h_48h_#23 - 9	hours:48 | treatment:Serum | concentration:-	RAW_FILE_NAME=HP_140228_AP5_24h_48h
SUBJECT_SAMPLE_FACTORS           	-	HP_140321_Betti_AP6_48h_#62 - 9	hours:48 | treatment:Serum | concentration:-	RAW_FILE_NAME=HP_140321_Betti_AP6_48h
SUBJECT_SAMPLE_FACTORS           	-	HP_140214_AP4and5_48h_10min_#44 - 4	hours:48 | treatment:STS | concentration:0.3 µM	RAW_FILE_NAME=HP_140214_AP4and5_48h_10min
SUBJECT_SAMPLE_FACTORS           	-	HP_140228_AP5_24h_48h_#18 - 4	hours:48 | treatment:STS | concentration:0.3 µM	RAW_FILE_NAME=HP_140228_AP5_24h_48h
SUBJECT_SAMPLE_FACTORS           	-	HP_140321_Betti_AP6_48h_#57 - 4	hours:48 | treatment:STS | concentration:0.3 µM	RAW_FILE_NAME=HP_140321_Betti_AP6_48h
SUBJECT_SAMPLE_FACTORS           	-	HP_140214_AP4and5_48h_10min_#43 - 3	hours:48 | treatment:TNFα | concentration:10 ng/ml	RAW_FILE_NAME=HP_140214_AP4and5_48h_10min
SUBJECT_SAMPLE_FACTORS           	-	HP_140228_AP5_24h_48h_#17 - 3	hours:48 | treatment:TNFα | concentration:10 ng/ml	RAW_FILE_NAME=HP_140228_AP5_24h_48h
SUBJECT_SAMPLE_FACTORS           	-	HP_140321_Betti_AP6_48h_#56 - 3	hours:48 | treatment:TNFα | concentration:10 ng/ml	RAW_FILE_NAME=HP_140321_Betti_AP6_48h
SUBJECT_SAMPLE_FACTORS           	-	HP_140214_AP4and5_48h_10min_#47 - 7	hours:48 | treatment:TPG | concentration:2 µM	RAW_FILE_NAME=HP_140214_AP4and5_48h_10min
SUBJECT_SAMPLE_FACTORS           	-	HP_140228_AP5_24h_48h_#21 - 7	hours:48 | treatment:TPG | concentration:2 µM	RAW_FILE_NAME=HP_140228_AP5_24h_48h
SUBJECT_SAMPLE_FACTORS           	-	HP_140321_Betti_AP6_48h_#60 - 7	hours:48 | treatment:TPG | concentration:2 µM	RAW_FILE_NAME=HP_140321_Betti_AP6_48h
SUBJECT_SAMPLE_FACTORS           	-	HP_140214_AP4and5_48h_10min_#48 - 8	hours:48 | treatment:VAL | concentration:10 µM	RAW_FILE_NAME=HP_140214_AP4and5_48h_10min
SUBJECT_SAMPLE_FACTORS           	-	HP_140228_AP5_24h_48h_#22 - 8	hours:48 | treatment:VAL | concentration:10 µM	RAW_FILE_NAME=HP_140228_AP5_24h_48h
SUBJECT_SAMPLE_FACTORS           	-	HP_140321_Betti_AP6_48h_#61 - 8	hours:48 | treatment:VAL | concentration:10 µM	RAW_FILE_NAME=HP_140321_Betti_AP6_48h
SUBJECT_SAMPLE_FACTORS           	-	HP_140214_AP4and5_48h_10min_#42 - 2	hours:48 | treatment:vehicle (DMSO) | concentration:-	RAW_FILE_NAME=HP_140214_AP4and5_48h_10min
SUBJECT_SAMPLE_FACTORS           	-	HP_140214_AP4and5_48h_10min_#52 - 12	hours:48 | treatment:vehicle (DMSO) | concentration:-	RAW_FILE_NAME=HP_140214_AP4and5_48h_10min
SUBJECT_SAMPLE_FACTORS           	-	HP_140228_AP5_24h_48h_#16 - 2	hours:48 | treatment:vehicle (DMSO) | concentration:-	RAW_FILE_NAME=HP_140228_AP5_24h_48h
SUBJECT_SAMPLE_FACTORS           	-	HP_140228_AP5_24h_48h_#26 - 12	hours:48 | treatment:vehicle (DMSO) | concentration:-	RAW_FILE_NAME=HP_140228_AP5_24h_48h
SUBJECT_SAMPLE_FACTORS           	-	HP_140321_Betti_AP6_48h_#55 - 2	hours:48 | treatment:vehicle (DMSO) | concentration:-	RAW_FILE_NAME=HP_140321_Betti_AP6_48h
SUBJECT_SAMPLE_FACTORS           	-	HP_140321_Betti_AP6_48h_#65 - 12	hours:48 | treatment:vehicle (DMSO) | concentration:-	RAW_FILE_NAME=HP_140321_Betti_AP6_48h
SUBJECT_SAMPLE_FACTORS           	-	HP_140211_AP4_6h_24h_#45 - 5	hours:6 | treatment:CHX | concentration:20 µg/ml	RAW_FILE_NAME=HP_140211_AP4_6h_24h
SUBJECT_SAMPLE_FACTORS           	-	HP_140217_AP5_1h_6h_#110 - 5	hours:6 | treatment:CHX | concentration:20 µg/ml	RAW_FILE_NAME=HP_140217_AP5_1h_6h
SUBJECT_SAMPLE_FACTORS           	-	HP_140313_AP6_6h_24h_#45 - 5	hours:6 | treatment:CHX | concentration:20 µg/ml	RAW_FILE_NAME=HP_140313_AP6_6h_24h
SUBJECT_SAMPLE_FACTORS           	-	HP_140211_AP4_6h_24h_#46 - 6	hours:6 | treatment:ETO | concentration:10 µM	RAW_FILE_NAME=HP_140211_AP4_6h_24h
SUBJECT_SAMPLE_FACTORS           	-	HP_140217_AP5_1h_6h_#111 - 6	hours:6 | treatment:ETO | concentration:10 µM	RAW_FILE_NAME=HP_140217_AP5_1h_6h
SUBJECT_SAMPLE_FACTORS           	-	HP_140313_AP6_6h_24h_#46 - 6	hours:6 | treatment:ETO | concentration:10 µM	RAW_FILE_NAME=HP_140313_AP6_6h_24h
SUBJECT_SAMPLE_FACTORS           	-	HP_140211_AP4_6h_24h_#50 - 10	hours:6 | treatment:MC | concentration:10 µM	RAW_FILE_NAME=HP_140211_AP4_6h_24h
SUBJECT_SAMPLE_FACTORS           	-	HP_140217_AP5_1h_6h_#115 - 10	hours:6 | treatment:MC | concentration:10 µM	RAW_FILE_NAME=HP_140217_AP5_1h_6h
SUBJECT_SAMPLE_FACTORS           	-	HP_140313_AP6_6h_24h_#50 - 10	hours:6 | treatment:MC | concentration:10 µM	RAW_FILE_NAME=HP_140313_AP6_6h_24h
SUBJECT_SAMPLE_FACTORS           	-	HP_140211_AP4_6h_24h_#49 - 9	hours:6 | treatment:Serum | concentration:-	RAW_FILE_NAME=HP_140211_AP4_6h_24h
SUBJECT_SAMPLE_FACTORS           	-	HP_140217_AP5_1h_6h_#114 - 9	hours:6 | treatment:Serum | concentration:-	RAW_FILE_NAME=HP_140217_AP5_1h_6h
SUBJECT_SAMPLE_FACTORS           	-	HP_140313_AP6_6h_24h_#49 - 9	hours:6 | treatment:Serum | concentration:-	RAW_FILE_NAME=HP_140313_AP6_6h_24h
SUBJECT_SAMPLE_FACTORS           	-	HP_140211_AP4_6h_24h_#44 - 4	hours:6 | treatment:STS | concentration:0.3 µM	RAW_FILE_NAME=HP_140211_AP4_6h_24h
SUBJECT_SAMPLE_FACTORS           	-	HP_140217_AP5_1h_6h_#109 - 4	hours:6 | treatment:STS | concentration:0.3 µM	RAW_FILE_NAME=HP_140217_AP5_1h_6h
SUBJECT_SAMPLE_FACTORS           	-	HP_140313_AP6_6h_24h_#44 - 4	hours:6 | treatment:STS | concentration:0.3 µM	RAW_FILE_NAME=HP_140313_AP6_6h_24h
SUBJECT_SAMPLE_FACTORS           	-	HP_140211_AP4_6h_24h_#43 - 3	hours:6 | treatment:TNFα | concentration:10 ng/ml	RAW_FILE_NAME=HP_140211_AP4_6h_24h
SUBJECT_SAMPLE_FACTORS           	-	HP_140217_AP5_1h_6h_#108 - 3	hours:6 | treatment:TNFα | concentration:10 ng/ml	RAW_FILE_NAME=HP_140217_AP5_1h_6h
SUBJECT_SAMPLE_FACTORS           	-	HP_140313_AP6_6h_24h_#43 - 3	hours:6 | treatment:TNFα | concentration:10 ng/ml	RAW_FILE_NAME=HP_140313_AP6_6h_24h
SUBJECT_SAMPLE_FACTORS           	-	HP_140211_AP4_6h_24h_#47 - 7	hours:6 | treatment:TPG | concentration:2 µM	RAW_FILE_NAME=HP_140211_AP4_6h_24h
SUBJECT_SAMPLE_FACTORS           	-	HP_140217_AP5_1h_6h_#112 - 7	hours:6 | treatment:TPG | concentration:2 µM	RAW_FILE_NAME=HP_140217_AP5_1h_6h
SUBJECT_SAMPLE_FACTORS           	-	HP_140313_AP6_6h_24h_#47 - 7	hours:6 | treatment:TPG | concentration:2 µM	RAW_FILE_NAME=HP_140313_AP6_6h_24h
SUBJECT_SAMPLE_FACTORS           	-	HP_140211_AP4_6h_24h_#48 - 8	hours:6 | treatment:VAL | concentration:10 µM	RAW_FILE_NAME=HP_140211_AP4_6h_24h
SUBJECT_SAMPLE_FACTORS           	-	HP_140217_AP5_1h_6h_#113 - 8	hours:6 | treatment:VAL | concentration:10 µM	RAW_FILE_NAME=HP_140217_AP5_1h_6h
SUBJECT_SAMPLE_FACTORS           	-	HP_140313_AP6_6h_24h_#48 - 8	hours:6 | treatment:VAL | concentration:10 µM	RAW_FILE_NAME=HP_140313_AP6_6h_24h
SUBJECT_SAMPLE_FACTORS           	-	HP_140211_AP4_6h_24h_#42 - 2	hours:6 | treatment:vehicle (DMSO) | concentration:-	RAW_FILE_NAME=HP_140211_AP4_6h_24h
SUBJECT_SAMPLE_FACTORS           	-	HP_140211_AP4_6h_24h_#52 - 12	hours:6 | treatment:vehicle (DMSO) | concentration:-	RAW_FILE_NAME=HP_140211_AP4_6h_24h
SUBJECT_SAMPLE_FACTORS           	-	HP_140217_AP5_1h_6h_#107 - 2	hours:6 | treatment:vehicle (DMSO) | concentration:-	RAW_FILE_NAME=HP_140217_AP5_1h_6h
SUBJECT_SAMPLE_FACTORS           	-	HP_140217_AP5_1h_6h_#117 - 12	hours:6 | treatment:vehicle (DMSO) | concentration:-	RAW_FILE_NAME=HP_140217_AP5_1h_6h
SUBJECT_SAMPLE_FACTORS           	-	HP_140313_AP6_6h_24h_#42 - 2	hours:6 | treatment:vehicle (DMSO) | concentration:-	RAW_FILE_NAME=HP_140313_AP6_6h_24h
SUBJECT_SAMPLE_FACTORS           	-	HP_140313_AP6_6h_24h_#52 - 12	hours:6 | treatment:vehicle (DMSO) | concentration:-	RAW_FILE_NAME=HP_140313_AP6_6h_24h
#COLLECTION
CO:COLLECTION_SUMMARY            	Cultured cells were washed, trypsinized, counted and flash-frozen in liquid N2
CO:COLLECTION_SUMMARY            	and stored at -80°C.
CO:SAMPLE_TYPE                   	Fibroblasts
CO:COLLECTION_METHOD             	Trypsinization of cultured cells
CO:STORAGE_CONDITIONS            	-80℃
#TREATMENT
TR:TREATMENT_SUMMARY             	Mouse NIH-3T3 fibroblasts were cultivated in DMEM high glucose medium containing
TR:TREATMENT_SUMMARY             	heat-inactivated fetal calf serum (FCS, 10%). After cultivation for 24 h, cells
TR:TREATMENT_SUMMARY             	were treated with vehicle, TNFα (10 ng/ml), STS (0.3 µM), CHX (20 µg/ml), ETO
TR:TREATMENT_SUMMARY             	(10 µM), TPG (2 µM), VAL (10 µM), MC (10 µM) at 37°C and 5% CO2. Serum
TR:TREATMENT_SUMMARY             	depletion of NIH-3T3 fibroblasts was achieved by cultivation of cells in
TR:TREATMENT_SUMMARY             	serum-free DMEM.
TR:TREATMENT_VEHICLE             	DMSO
TR:CELL_MEDIA                    	DMEM + 10% FCS
TR:CELL_ENVIR_COND               	37°C, 5% CO2
#SAMPLEPREP
SP:SAMPLEPREP_SUMMARY            	Phospholipids were extracted from cell pellets by successive addition of PBS pH
SP:SAMPLEPREP_SUMMARY            	7.4, methanol, chloroform, and saline to a final ratio of 14:34:35:17.
SP:SAMPLEPREP_SUMMARY            	Evaporation of the organic layer yielded a lipid film that was dissolved in
SP:SAMPLEPREP_SUMMARY            	methanol and subjected to UPLC-MS/MS.
SP:EXTRACT_STORAGE               	-20℃
#CHROMATOGRAPHY
CH:CHROMATOGRAPHY_SUMMARY        	Chromatographic separation of phospholipids was carried out on an Acquity BEH C8
CH:CHROMATOGRAPHY_SUMMARY        	column (1.7 μm, 2.1×100 mm, Waters, Milford, MA) using an Acquity UHPLC.
CH:INSTRUMENT_NAME               	Waters Acquity H-Class
CH:COLUMN_NAME                   	Waters Acquity BEH C8 (100 x 2.1mm, 1.7um)
CH:CHROMATOGRAPHY_TYPE           	Reversed phase
#ANALYSIS
AN:ANALYSIS_TYPE                 	MS
#MS
MS:INSTRUMENT_NAME               	ABI Sciex 5500 QTrap
MS:INSTRUMENT_TYPE               	Triple quadrupole
MS:MS_TYPE                       	ESI
MS:MS_COMMENTS                   	Targeted MRM with pre-optimized settings and subsequent automated integration of
MS:MS_COMMENTS                   	selected signals using Analyst 1.6 (Sciex).
MS:ION_MODE                      	NEGATIVE
#MS_METABOLITE_DATA
MS_METABOLITE_DATA:UNITS         	Relative intensity
MS_METABOLITE_DATA_START
Samples	HP_140211_AP4_10m_1h_#45 - 5	HP_140214_AP4und5_48h_10min_#10 - 5	HP_140311_AP6_10min_#45 - 5	HP_140211_AP4_10m_1h_#46 - 6	HP_140214_AP4und5_48h_10min_#11 - 6	HP_140311_AP6_10min_#46 - 6	HP_140211_AP4_10m_1h_#50 - 10	HP_140214_AP4und5_48h_10min_#15 - 10	HP_140311_AP6_10min_#50 - 10	HP_140211_AP4_10m_1h_#49 - 9	HP_140214_AP4und5_48h_10min_#14 - 9	HP_140311_AP6_10min_#49 - 9	HP_140211_AP4_10m_1h_#44 - 4	HP_140214_AP4und5_48h_10min_#9 - 4	HP_140311_AP6_10min_#44 - 4	HP_140211_AP4_10m_1h_#43 - 3	HP_140214_AP4und5_48h_10min_#8 - 3	HP_140311_AP6_10min_#43 - 3	HP_140211_AP4_10m_1h_#47 - 7	HP_140214_AP4und5_48h_10min_#12 - 7	HP_140311_AP6_10min_#47 - 7	HP_140211_AP4_10m_1h_#48 - 8	HP_140214_AP4und5_48h_10min_#13 - 8	HP_140311_AP6_10min_#48 - 8	HP_140211_AP4_10m_1h_#42 - 2	HP_140211_AP4_10m_1h_#52 - 12	HP_140214_AP4und5_48h_10min_#17 - 12	HP_140214_AP4und5_48h_10min_#7 - 2	HP_140311_AP6_10min_#42 - 2	HP_140311_AP6_10min_#52 - 12	HP_140211_AP4_10min_1h_#10 - 5	HP_140217_AP5_1h_6h_#45 - 5	HP_140312_AP6_1h_#45 - 5	HP_140211_AP4_10min_1h_#11 - 6	HP_140217_AP5_1h_6h_#46 - 6	HP_140312_AP6_1h_#46 - 6	HP_140211_AP4_10min_1h_#15 - 10	HP_140217_AP5_1h_6h_#50 - 10	HP_140312_AP6_1h_#50 - 10	HP_140211_AP4_10min_1h_#14 - 9	HP_140217_AP5_1h_6h_#49 - 9	HP_140312_AP6_1h_#49 - 9	HP_140211_AP4_10min_1h_#9 - 4	HP_140217_AP5_1h_6h_#44 - 4	HP_140312_AP6_1h_#44 - 4	HP_140211_AP4_10min_1h_#8 - 3	HP_140217_AP5_1h_6h_#43 - 3	HP_140312_AP6_1h_#43 - 3	HP_140211_AP4_10min_1h_#12 - 7	HP_140217_AP5_1h_6h_#47 - 7	HP_140312_AP6_1h_#47 - 7	HP_140211_AP4_10min_1h_#13 - 8	HP_140217_AP5_1h_6h_#48 - 8	HP_140312_AP6_1h_#48 - 8	HP_140211_AP4_10min_1h_#17 - 12	HP_140211_AP4_10min_1h_#7 - 2	HP_140217_AP5_1h_6h_#42 - 2	HP_140217_AP5_1h_6h_#52 - 12	HP_140312_AP6_1h_#42 - 2	HP_140312_AP6_1h_#52 - 12	HP_140213_AP4_6h_24_restart_#30 - 5	HP_140227_AP5_24h_48h_#45 - 5	HP_140314_AP6_24h_#19 - 5	HP_140213_AP4_6h_24_restart_#31 - 6	HP_140227_AP5_24h_48h_#46 - 6	HP_140314_AP6_24h_#20 - 6	HP_140213_AP4_6h_24_restart_#35 - 10	HP_140227_AP5_24h_48h_#50 - 10	HP_140314_AP6_24h_#24 - 10	HP_140213_AP4_6h_24_restart_#34 - 9	HP_140227_AP5_24h_48h_#49 - 9	HP_140314_AP6_24h_#23 - 9	HP_140213_AP4_6h_24_restart_#29 - 4	HP_140227_AP5_24h_48h_#44 - 4	HP_140314_AP6_24h_#18 - 4	HP_140213_AP4_6h_24_restart_#28 - 3	HP_140227_AP5_24h_48h_#43 - 3	HP_140314_AP6_24h_#17 - 3	HP_140213_AP4_6h_24_restart_#32 - 7	HP_140227_AP5_24h_48h_#47 - 7	HP_140314_AP6_24h_#21 - 7	HP_140213_AP4_6h_24_restart_#33 - 8	HP_140227_AP5_24h_48h_#48 - 8	HP_140314_AP6_24h_#22 - 8	HP_140213_AP4_6h_24_restart_#27 - 2	HP_140213_AP4_6h_24_restart_#37 - 12	HP_140227_AP5_24h_48h_#42 - 2	HP_140227_AP5_24h_48h_#52 - 12	HP_140314_AP6_24h_#16 - 2	HP_140314_AP6_24h_#26 - 12	HP_140214_AP4and5_48h_10min_#45 - 5	HP_140228_AP5_24h_48h_#19 - 5	HP_140321_Betti_AP6_48h_#58 - 5	HP_140214_AP4and5_48h_10min_#46 - 6	HP_140228_AP5_24h_48h_#20 - 6	HP_140321_Betti_AP6_48h_#59 - 6	HP_140214_AP4and5_48h_10min_#50 - 10	HP_140228_AP5_24h_48h_#24 - 10	HP_140321_Betti_AP6_48h_#63 - 10	HP_140214_AP4and5_48h_10min_#49 - 9	HP_140228_AP5_24h_48h_#23 - 9	HP_140321_Betti_AP6_48h_#62 - 9	HP_140214_AP4and5_48h_10min_#44 - 4	HP_140228_AP5_24h_48h_#18 - 4	HP_140321_Betti_AP6_48h_#57 - 4	HP_140214_AP4and5_48h_10min_#43 - 3	HP_140228_AP5_24h_48h_#17 - 3	HP_140321_Betti_AP6_48h_#56 - 3	HP_140214_AP4and5_48h_10min_#47 - 7	HP_140228_AP5_24h_48h_#21 - 7	HP_140321_Betti_AP6_48h_#60 - 7	HP_140214_AP4and5_48h_10min_#48 - 8	HP_140228_AP5_24h_48h_#22 - 8	HP_140321_Betti_AP6_48h_#61 - 8	HP_140214_AP4and5_48h_10min_#42 - 2	HP_140214_AP4and5_48h_10min_#52 - 12	HP_140228_AP5_24h_48h_#16 - 2	HP_140228_AP5_24h_48h_#26 - 12	HP_140321_Betti_AP6_48h_#55 - 2	HP_140321_Betti_AP6_48h_#65 - 12	HP_140211_AP4_6h_24h_#45 - 5	HP_140217_AP5_1h_6h_#110 - 5	HP_140313_AP6_6h_24h_#45 - 5	HP_140211_AP4_6h_24h_#46 - 6	HP_140217_AP5_1h_6h_#111 - 6	HP_140313_AP6_6h_24h_#46 - 6	HP_140211_AP4_6h_24h_#50 - 10	HP_140217_AP5_1h_6h_#115 - 10	HP_140313_AP6_6h_24h_#50 - 10	HP_140211_AP4_6h_24h_#49 - 9	HP_140217_AP5_1h_6h_#114 - 9	HP_140313_AP6_6h_24h_#49 - 9	HP_140211_AP4_6h_24h_#44 - 4	HP_140217_AP5_1h_6h_#109 - 4	HP_140313_AP6_6h_24h_#44 - 4	HP_140211_AP4_6h_24h_#43 - 3	HP_140217_AP5_1h_6h_#108 - 3	HP_140313_AP6_6h_24h_#43 - 3	HP_140211_AP4_6h_24h_#47 - 7	HP_140217_AP5_1h_6h_#112 - 7	HP_140313_AP6_6h_24h_#47 - 7	HP_140211_AP4_6h_24h_#48 - 8	HP_140217_AP5_1h_6h_#113 - 8	HP_140313_AP6_6h_24h_#48 - 8	HP_140211_AP4_6h_24h_#42 - 2	HP_140211_AP4_6h_24h_#52 - 12	HP_140217_AP5_1h_6h_#107 - 2	HP_140217_AP5_1h_6h_#117 - 12	HP_140313_AP6_6h_24h_#42 - 2	HP_140313_AP6_6h_24h_#52 - 12
Factors	hours:0.17 | treatment:CHX | concentration:20 µg/ml	hours:0.17 | treatment:CHX | concentration:20 µg/ml	hours:0.17 | treatment:CHX | concentration:20 µg/ml	hours:0.17 | treatment:ETO | concentration:10 µM	hours:0.17 | treatment:ETO | concentration:10 µM	hours:0.17 | treatment:ETO | concentration:10 µM	hours:0.17 | treatment:MC | concentration:10 µM	hours:0.17 | treatment:MC | concentration:10 µM	hours:0.17 | treatment:MC | concentration:10 µM	hours:0.17 | treatment:Serum | concentration:-	hours:0.17 | treatment:Serum | concentration:-	hours:0.17 | treatment:Serum | concentration:-	hours:0.17 | treatment:STS | concentration:0.3 µM	hours:0.17 | treatment:STS | concentration:0.3 µM	hours:0.17 | treatment:STS | concentration:0.3 µM	hours:0.17 | treatment:TNFα | concentration:10 ng/ml	hours:0.17 | treatment:TNFα | concentration:10 ng/ml	hours:0.17 | treatment:TNFα | concentration:10 ng/ml	hours:0.17 | treatment:TPG | concentration:2 µM	hours:0.17 | treatment:TPG | concentration:2 µM	hours:0.17 | treatment:TPG | concentration:2 µM	hours:0.17 | treatment:VAL | concentration:10 µM	hours:0.17 | treatment:VAL | concentration:10 µM	hours:0.17 | treatment:VAL | concentration:10 µM	hours:0.17 | treatment:vehicle (DMSO) | concentration:-	hours:0.17 | treatment:vehicle (DMSO) | concentration:-	hours:0.17 | treatment:vehicle (DMSO) | concentration:-	hours:0.17 | treatment:vehicle (DMSO) | concentration:-	hours:0.17 | treatment:vehicle (DMSO) | concentration:-	hours:0.17 | treatment:vehicle (DMSO) | concentration:-	hours:1 | treatment:CHX | concentration:20 µg/ml	hours:1 | treatment:CHX | concentration:20 µg/ml	hours:1 | treatment:CHX | concentration:20 µg/ml	hours:1 | treatment:ETO | concentration:10 µM	hours:1 | treatment:ETO | concentration:10 µM	hours:1 | treatment:ETO | concentration:10 µM	hours:1 | treatment:MC | concentration:10 µM	hours:1 | treatment:MC | concentration:10 µM	hours:1 | treatment:MC | concentration:10 µM	hours:1 | treatment:Serum | concentration:-	hours:1 | treatment:Serum | concentration:-	hours:1 | treatment:Serum | concentration:-	hours:1 | treatment:STS | concentration:0.3 µM	hours:1 | treatment:STS | concentration:0.3 µM	hours:1 | treatment:STS | concentration:0.3 µM	hours:1 | treatment:TNFα | concentration:10 ng/ml	hours:1 | treatment:TNFα | concentration:10 ng/ml	hours:1 | treatment:TNFα | concentration:10 ng/ml	hours:1 | treatment:TPG | concentration:2 µM	hours:1 | treatment:TPG | concentration:2 µM	hours:1 | treatment:TPG | concentration:2 µM	hours:1 | treatment:VAL | concentration:10 µM	hours:1 | treatment:VAL | concentration:10 µM	hours:1 | treatment:VAL | concentration:10 µM	hours:1 | treatment:vehicle (DMSO) | concentration:-	hours:1 | treatment:vehicle (DMSO) | concentration:-	hours:1 | treatment:vehicle (DMSO) | concentration:-	hours:1 | treatment:vehicle (DMSO) | concentration:-	hours:1 | treatment:vehicle (DMSO) | concentration:-	hours:1 | treatment:vehicle (DMSO) | concentration:-	hours:24 | treatment:CHX | concentration:20 µg/ml	hours:24 | treatment:CHX | concentration:20 µg/ml	hours:24 | treatment:CHX | concentration:20 µg/ml	hours:24 | treatment:ETO | concentration:10 µM	hours:24 | treatment:ETO | concentration:10 µM	hours:24 | treatment:ETO | concentration:10 µM	hours:24 | treatment:MC | concentration:10 µM	hours:24 | treatment:MC | concentration:10 µM	hours:24 | treatment:MC | concentration:10 µM	hours:24 | treatment:Serum | concentration:-	hours:24 | treatment:Serum | concentration:-	hours:24 | treatment:Serum | concentration:-	hours:24 | treatment:STS | concentration:0.3 µM	hours:24 | treatment:STS | concentration:0.3 µM	hours:24 | treatment:STS | concentration:0.3 µM	hours:24 | treatment:TNFα | concentration:10 ng/ml	hours:24 | treatment:TNFα | concentration:10 ng/ml	hours:24 | treatment:TNFα | concentration:10 ng/ml	hours:24 | treatment:TPG | concentration:2 µM	hours:24 | treatment:TPG | concentration:2 µM	hours:24 | treatment:TPG | concentration:2 µM	hours:24 | treatment:VAL | concentration:10 µM	hours:24 | treatment:VAL | concentration:10 µM	hours:24 | treatment:VAL | concentration:10 µM	hours:24 | treatment:vehicle (DMSO) | concentration:-	hours:24 | treatment:vehicle (DMSO) | concentration:-	hours:24 | treatment:vehicle (DMSO) | concentration:-	hours:24 | treatment:vehicle (DMSO) | concentration:-	hours:24 | treatment:vehicle (DMSO) | concentration:-	hours:24 | treatment:vehicle (DMSO) | concentration:-	hours:48 | treatment:CHX | concentration:20 µg/ml	hours:48 | treatment:CHX | concentration:20 µg/ml	hours:48 | treatment:CHX | concentration:20 µg/ml	hours:48 | treatment:ETO | concentration:10 µM	hours:48 | treatment:ETO | concentration:10 µM	hours:48 | treatment:ETO | concentration:10 µM	hours:48 | treatment:MC | concentration:10 µM	hours:48 | treatment:MC | concentration:10 µM	hours:48 | treatment:MC | concentration:10 µM	hours:48 | treatment:Serum | concentration:-	hours:48 | treatment:Serum | concentration:-	hours:48 | treatment:Serum | concentration:-	hours:48 | treatment:STS | concentration:0.3 µM	hours:48 | treatment:STS | concentration:0.3 µM	hours:48 | treatment:STS | concentration:0.3 µM	hours:48 | treatment:TNFα | concentration:10 ng/ml	hours:48 | treatment:TNFα | concentration:10 ng/ml	hours:48 | treatment:TNFα | concentration:10 ng/ml	hours:48 | treatment:TPG | concentration:2 µM	hours:48 | treatment:TPG | concentration:2 µM	hours:48 | treatment:TPG | concentration:2 µM	hours:48 | treatment:VAL | concentration:10 µM	hours:48 | treatment:VAL | concentration:10 µM	hours:48 | treatment:VAL | concentration:10 µM	hours:48 | treatment:vehicle (DMSO) | concentration:-	hours:48 | treatment:vehicle (DMSO) | concentration:-	hours:48 | treatment:vehicle (DMSO) | concentration:-	hours:48 | treatment:vehicle (DMSO) | concentration:-	hours:48 | treatment:vehicle (DMSO) | concentration:-	hours:48 | treatment:vehicle (DMSO) | concentration:-	hours:6 | treatment:CHX | concentration:20 µg/ml	hours:6 | treatment:CHX | concentration:20 µg/ml	hours:6 | treatment:CHX | concentration:20 µg/ml	hours:6 | treatment:ETO | concentration:10 µM	hours:6 | treatment:ETO | concentration:10 µM	hours:6 | treatment:ETO | concentration:10 µM	hours:6 | treatment:MC | concentration:10 µM	hours:6 | treatment:MC | concentration:10 µM	hours:6 | treatment:MC | concentration:10 µM	hours:6 | treatment:Serum | concentration:-	hours:6 | treatment:Serum | concentration:-	hours:6 | treatment:Serum | concentration:-	hours:6 | treatment:STS | concentration:0.3 µM	hours:6 | treatment:STS | concentration:0.3 µM	hours:6 | treatment:STS | concentration:0.3 µM	hours:6 | treatment:TNFα | concentration:10 ng/ml	hours:6 | treatment:TNFα | concentration:10 ng/ml	hours:6 | treatment:TNFα | concentration:10 ng/ml	hours:6 | treatment:TPG | concentration:2 µM	hours:6 | treatment:TPG | concentration:2 µM	hours:6 | treatment:TPG | concentration:2 µM	hours:6 | treatment:VAL | concentration:10 µM	hours:6 | treatment:VAL | concentration:10 µM	hours:6 | treatment:VAL | concentration:10 µM	hours:6 | treatment:vehicle (DMSO) | concentration:-	hours:6 | treatment:vehicle (DMSO) | concentration:-	hours:6 | treatment:vehicle (DMSO) | concentration:-	hours:6 | treatment:vehicle (DMSO) | concentration:-	hours:6 | treatment:vehicle (DMSO) | concentration:-	hours:6 | treatment:vehicle (DMSO) | concentration:-	
Phosphatidylinositol(16:0/18:1)	1.2670	0.6480	0.7330	1.1430	1.0750	0.9030	1.1220	0.5000	0.6880	0.7580	0.6050	0.3840	1.7970	1.0030	1.1950	2.2830	1.5260	1.1580	3.5410	3.0020	3.9760	1.3820	1.0210	1.6610	1.5080	1.1000	0.8890	1.0060	1.4210	0.6510	0.6500	0.9740	0.4190	1.1370	1.1680	0.7690	0.9760	0.6650	1.2420	0.9300	0.5770	0.5900	1.0620	0.5580	0.4660	4.1260	1.9120	2.4160	3.9210	3.3940	3.1910	2.2760	0.9280	2.2330	1.0500	1.9810	1.0750	1.0610	0.9480	1.3700	1.4950	0.4860	1.3970	1.9790	1.3400	1.7470	1.7180	2.0360	4.8610	0.9820	1.1320	0.5460	0.8310	1.3240	0.7620	2.0070	3.1500	2.3580	3.6690	3.9970	5.1070	12.0160	8.0320	12.1230	1.2790	1.4800	2.7640	0.9860	2.4210	1.7300	2.0480	2.0550	1.4970	4.0960	2.4020	4.3410	1.9680	2.3410	6.8800	0.6580	0.6180	1.2930	1.2670	1.4420	1.1240	4.4210	4.9010	4.6110	1.6330	4.1260	4.2230	8.2330	5.5110	8.8990	3.4310	4.4330	3.7750	2.5620	3.5590	3.8940	0.4870	0.9280	1.5960	1.1940	0.5950	0.8370	1.4330	1.1170	2.3700	1.7880	1.2610	1.4650	1.2120	0.7750	1.2650	2.2150	1.1510	1.5910	3.9780	3.9630	4.9790	7.7640	7.8270	7.9660	1.2010	0.7720	0.9820	0.7390	0.8330	1.2000
Phosphatidylinositol(16:0/20:3 n-6)	1.1260	0.6910	0.6190	0.8350	0.7980	1.2260	1.0120	0.8090	0.7560	0.7850	0.6260	0.9580	0.7370	0.8530	0.5520	0.7760	0.8760	0.5200	0.7960	0.4220	1.1450	1.0080	0.4980	0.6440	1.0580	0.6990	0.7790	0.5190	0.5260	0.5220	0.5940	0.7390	0.9760	0.7810	0.7480	0.4910	0.8100	0.6350	0.5200	0.8620	0.4260	0.7200	0.6760	0.3360	0.4660	1.1830	0.7650	0.7590	1.5070	0.9260	1.0450	1.0840	0.6880	0.9610	0.6460	1.2700	0.6750	0.3780	0.7600	0.5640	0.5290	0.8030	0.3500	0.9780	0.6510	0.7170	1.1080	1.0420	2.5080	0.6140	0.5290	0.4560	0.6340	0.8680	0.4350	1.0460	0.7390	0.7250	1.6880	1.2760	1.7440	2.4920	2.4130	2.5600	0.7880	0.8260	0.7150	0.4150	0.7690	1.1950	0.6170	0.5470	0.5450	1.4950	1.0890	1.7150	1.1220	1.2640	1.5700	0.2750	0.4410	0.3650	0.5800	0.3710	0.3990	1.4650	0.7260	0.7930	0.9210	1.2540	1.1990	2.5820	2.3170	2.6510	0.8140	1.1280	0.6590	0.5770	0.7710	0.5130	0.6490	0.5630	0.5320	0.6710	0.5000	0.8370	0.8570	0.6640	1.2540	0.5080	0.4780	1.0280	0.9640	0.5870	0.6330	1.1490	0.9660	0.7700	1.5570	1.3450	1.6080	2.0930	1.7410	2.4170	0.6530	0.9440	0.6810	0.6340	0.7300	0.5650
Phosphatidylinositol(16:0/20:4)	5.1440	5.3630	6.7700	6.0730	5.0300	5.5450	5.4990	5.2580	5.6580	5.9850	5.6120	6.9020	5.3020	5.2330	6.1530	4.7120	5.8880	4.6280	6.2720	5.9740	6.5230	6.1970	5.9740	6.3240	6.1680	6.1120	4.7740	4.8890	6.3760	6.7100	5.3260	4.1100	4.8220	5.3680	4.4050	6.5130	5.6840	6.0520	6.0990	5.6470	5.6700	5.6970	5.7870	4.2530	6.0360	4.8750	4.4850	4.0020	6.3430	5.4860	5.9040	5.8340	6.2360	6.1820	5.9710	5.5200	5.1600	5.1130	5.9010	6.9730	3.2700	2.9880	4.1290	5.1720	5.1020	6.0820	4.5350	3.3340	5.3560	4.0850	4.4370	3.4490	5.5230	5.7600	6.4670	5.6730	5.1820	5.2620	4.0150	4.6560	4.7090	4.5740	4.1730	4.3410	5.9720	5.8170	5.6020	4.2590	6.1610	5.7560	3.6050	3.3850	4.7700	6.3070	5.2900	6.7060	4.2060	4.2400	5.1170	3.3010	3.3200	2.9520	6.3570	5.4810	6.8330	5.6150	4.4940	5.1870	4.1850	3.9680	3.8730	5.2980	4.8990	5.0530	6.2060	5.3830	5.3780	5.3180	4.5040	5.2870	4.9910	5.0130	5.6280	6.7680	3.7670	7.1250	5.2860	4.5010	7.0550	5.1440	4.4580	4.1860	6.7780	5.6130	5.2620	5.7210	5.0310	5.9040	4.2120	4.6940	5.3600	5.6680	5.7980	6.2740	5.4160	6.4520	5.4470	5.0450	6.8700	6.5040
Phosphatidylinositol(16:1/18:1)	1.1690	0.9120	1.0840	1.3370	0.8840	0.7830	1.1700	0.9130	1.0390	0.9590	0.8010	0.9690	1.9370	1.7130	1.3100	2.7870	1.6560	1.5210	3.5610	3.9660	3.2250	1.4560	1.0210	1.1420	1.9530	1.0630	0.8570	1.5670	1.5710	1.0520	0.9140	1.0700	0.7770	1.2140	1.2250	1.0600	1.1700	0.7960	1.0490	1.4900	0.8520	0.8620	1.0720	0.9710	1.2370	3.6590	1.7590	2.5620	3.5400	3.5220	3.6430	1.5390	0.8380	1.0830	0.9820	2.2240	1.1790	0.5540	1.4260	1.2760	0.9040	1.2610	0.9390	1.8810	1.6740	2.1500	1.9010	2.3430	4.1800	1.3790	1.4580	1.2850	0.7620	1.3540	0.6090	2.2460	2.9600	2.3040	3.3230	3.5580	3.6250	3.4820	3.1500	3.2400	1.9770	1.9560	2.7320	1.7490	2.3140	2.6340	0.9240	1.0300	1.3850	3.3560	2.4500	1.7260	2.3860	2.6010	4.8200	1.3470	2.1370	1.1330	1.0490	1.7390	1.3730	4.4600	4.7160	5.6700	1.3470	2.2970	2.0390	1.4490	2.1520	2.2460	4.0930	5.0550	4.5620	3.4410	4.5040	4.2740	0.8180	1.1040	1.4330	1.3660	0.9070	0.8500	1.3830	1.5530	3.5580	1.8550	1.2830	0.6060	1.3720	0.6390	0.9950	2.3930	1.6420	2.2080	3.8560	3.3660	2.4480	2.9770	3.0430	2.5000	1.1490	1.1630	1.3670	0.9890	1.3650	0.9070
Phosphatidylinositol(18:0/20:3 n-6)	4.5010	5.0640	3.9450	6.0370	6.1320	4.3190	4.7780	5.4020	4.9440	5.2690	4.6740	3.9480	5.5320	5.0810	4.9620	6.8610	5.6820	4.3280	5.9180	4.0270	3.7190	6.1860	4.4760	4.4480	6.3830	5.9830	5.4470	4.6770	5.2600	4.0320	5.0780	4.7340	4.3090	5.6180	5.6580	4.8470	5.1120	4.7980	5.5610	5.7550	5.0780	5.1580	5.2220	5.5340	6.0360	6.4060	5.1230	6.6890	5.7500	4.1910	5.1060	7.2180	5.1370	6.5400	4.8250	5.9160	4.2510	5.8540	4.6720	4.7970	5.8320	5.7810	5.4640	5.7480	5.4460	5.4230	8.5380	10.3250	9.1650	6.2870	5.5140	6.9930	4.5290	5.5450	5.1030	5.9180	4.8010	5.6430	11.8980	10.8430	9.6110	16.2150	14.4650	12.6150	6.3060	6.2710	5.3180	6.7250	5.4750	4.9810	7.2380	7.4650	8.0770	7.6860	6.8640	7.1650	9.2890	9.2600	11.8240	5.1060	5.8960	5.7210	3.5370	5.0600	4.4050	5.8150	4.6690	4.3610	14.8000	12.9400	13.5930	16.3360	15.7890	13.4110	6.9090	6.3900	4.7490	5.6010	5.0970	6.5850	4.1480	5.4750	4.7840	5.2940	4.0860	5.3830	5.8290	7.2410	7.2360	6.6620	5.3280	5.5820	5.2320	5.2070	6.1140	7.1430	5.6350	5.2380	9.4530	7.2560	8.1060	13.4800	9.8430	12.0250	6.3100	5.9800	4.2230	6.4160	5.7220	4.8550
Phosphatidylinositol(18:0/20:4)	58.5620	58.0210	56.0090	52.8970	58.0490	56.5680	58.8970	56.5910	56.8810	60.3370	57.5640	54.6660	53.2780	54.0700	52.4040	49.4720	50.5470	53.2890	41.5790	40.0670	38.8420	53.9980	55.3400	53.9730	52.9240	57.2420	59.4370	52.3720	51.0090	56.6690	59.8430	60.2660	60.2700	58.1090	58.3980	56.9520	57.5720	57.2560	55.1570	58.1380	59.9840	58.6680	58.9420	59.2040	57.6810	40.3910	50.5170	43.6000	37.0900	37.7760	38.2960	53.8810	59.3890	55.3910	58.3650	52.9490	56.3600	59.1300	53.8240	56.3770	69.3810	67.9870	65.2130	52.7030	54.9290	47.4520	48.5740	43.7880	30.1880	66.8500	60.6830	67.5730	66.3580	59.3900	61.6170	49.2630	38.4260	38.7140	44.6660	32.1730	32.5390	24.5790	21.0720	19.4130	52.9920	52.1460	40.6540	57.3900	44.2550	45.9360	66.4840	62.5290	63.6720	45.3200	52.0900	45.8830	44.6260	40.1860	29.7330	70.5310	64.1150	66.2210	65.8400	64.4530	62.7770	37.9480	30.9750	29.9070	52.2600	37.3010	36.9810	34.2820	34.0940	26.4060	43.0940	39.4930	36.9050	47.4320	35.5870	39.5760	65.8480	59.4970	54.7430	57.8840	65.3570	53.3800	53.5970	52.4470	40.0990	61.2190	61.1070	59.6240	64.0170	63.0320	61.1350	47.1450	48.9410	48.1630	37.0370	36.4460	32.7530	38.8210	38.9450	36.9060	57.9230	56.8720	53.8630	58.5250	54.0630	54.9650
Phosphatidylinositol(18:0/22:5)	1.8070	2.1580	2.0850	2.9520	2.2390	1.4820	2.2940	1.8830	2.4810	2.1610	1.5250	2.2360	2.3070	2.2150	1.2860	2.7200	2.1320	2.3740	2.2960	1.9980	1.8690	2.7530	2.0970	1.3410	2.6530	1.9940	2.1150	2.1270	1.5800	2.4130	2.2060	2.1490	1.8800	1.8700	2.0610	2.3140	2.0270	2.3010	1.8650	1.9510	2.0390	2.0970	2.1630	2.1240	1.6260	4.2670	2.2430	3.0460	2.5660	2.0390	2.3990	3.2020	2.3680	2.3120	1.4930	2.3140	2.2280	1.8230	1.1390	1.8300	2.0040	2.0510	1.5710	2.2290	2.1440	2.3820	2.9820	3.0450	4.3660	1.6580	2.3390	2.1610	2.2600	1.9500	2.1210	2.3070	1.4760	1.7310	4.5530	3.6070	3.5560	9.3370	9.4930	10.6900	2.1890	2.0310	1.3740	2.0220	1.3720	2.0450	2.4270	2.1880	2.1810	2.5390	2.5150	2.6120	3.6400	3.1600	2.8830	2.1940	1.7210	1.4760	2.0190	1.8570	2.0880	2.0780	1.3500	1.1880	5.8790	4.3970	4.3230	7.5840	7.2320	7.4540	1.9500	1.9860	1.5370	1.7800	1.1570	1.2440	2.1440	2.0560	1.5990	2.1630	2.4800	1.7780	2.3710	2.4140	1.8090	2.8160	2.2180	2.6390	1.7080	2.3040	2.0380	3.6250	2.1250	2.6190	4.0290	2.6230	2.5640	6.5970	4.4960	5.6900	2.3430	2.2520	1.6090	2.6520	1.6170	2.6140
Phosphatidylinositol(18:0/22:6)	1.0860	1.2330	1.1830	1.9760	1.5140	1.1590	1.2060	1.3790	0.7560	1.3600	1.1460	0.5110	1.2100	1.5570	0.8260	1.6570	1.5480	1.2830	1.7300	1.4100	1.2700	1.8920	1.1890	1.0190	1.3090	1.4660	1.2980	1.6170	1.1340	0.5220	1.2030	1.1090	1.6030	1.3110	1.2630	1.3330	1.3450	1.6340	1.5560	1.3820	0.9140	1.1140	1.2670	1.6240	1.0090	2.5620	1.0930	2.8280	1.8880	1.5350	1.3540	2.0410	1.4620	1.8190	0.9140	1.4320	1.1790	1.4060	1.0110	0.8010	1.1560	0.7850	0.8740	1.6000	1.1220	1.1640	2.5200	3.0810	2.7220	1.1660	1.0570	1.2730	0.9680	1.5720	1.0350	2.0680	1.1640	1.1680	2.4590	2.0980	2.0730	9.0810	7.5460	7.7410	1.6010	1.4800	1.0160	1.4010	1.0900	0.8330	1.3310	1.2990	0.4090	2.3210	1.4990	0.6390	2.1170	1.6780	2.5580	1.0970	0.6180	0.1840	1.4100	0.6510	0.4820	1.7300	1.0170	0.3240	2.4390	2.2250	2.1960	6.4410	5.2130	5.7700	1.8560	1.6750	0.7560	1.2050	0.1720	0.6590	1.2070	0.8150	0.6520	1.4960	0.5720	0.6290	1.7780	1.6960	1.2540	1.9900	1.2830	1.3190	1.4660	0.8930	1.1950	2.2980	1.0220	1.1810	2.3100	1.5400	1.8030	4.5010	2.4670	3.4140	1.8840	1.2570	0.8910	0.8110	0.9910	1.7650
Phosphatidylinositol(18:1/18:1)	5.5430	3.7000	6.0880	7.5070	4.4610	4.9600	4.7540	4.4550	4.6760	3.6180	4.0330	6.3220	7.9150	6.4280	7.3440	11.5290	7.1110	8.1060	13.2530	12.9840	14.5660	6.9200	4.5230	6.3010	8.4840	5.8750	4.7420	6.6430	6.7400	5.8640	4.8130	5.1120	5.0020	6.4180	4.4860	5.0290	5.4160	4.6540	6.2330	5.1670	3.4330	3.7980	4.9100	4.9300	4.8960	17.1550	11.1070	14.3640	15.2430	14.3730	14.9460	8.0430	4.5160	5.6110	6.0480	9.9050	5.5060	4.9650	7.7590	5.3410	3.9180	3.7790	4.3060	7.6590	5.9620	10.7110	8.0490	10.3790	12.1680	3.7010	5.2850	2.8170	3.3310	5.5810	4.0220	8.1390	16.4360	15.5400	10.6350	16.9370	16.6130	10.8900	11.4750	11.5500	6.9120	6.5020	14.7170	5.9180	12.4420	11.8440	5.5680	5.4250	5.3000	10.8240	8.5840	11.0820	9.0330	10.1310	13.5530	3.6810	4.1030	3.8700	4.5290	4.3170	3.6070	16.0700	24.9650	25.7010	5.8490	12.3460	12.1690	9.2200	7.3480	9.1280	13.7010	15.8320	20.7510	12.5910	22.6120	18.9960	4.2180	4.9760	4.4770	6.2400	3.6850	6.1750	7.4340	6.2750	9.6780	5.5320	5.0340	4.4080	4.0620	4.1110	3.6500	10.9220	9.2570	8.8340	17.7050	15.2930	17.3690	10.7890	8.8660	9.1650	6.8280	4.5560	7.4030	4.9380	5.3160	5.1610
Phosphatidylinositol(18:1/20:3 n-6)	2.2070	2.2050	3.4820	2.5540	2.2220	2.9540	2.5190	2.1400	2.0670	2.0520	2.2740	1.8500	2.8550	2.8660	3.3030	2.4290	2.4250	2.3120	3.2780	3.2360	3.2060	2.5090	2.3130	2.7330	2.3970	2.2640	2.3390	3.3340	2.2090	3.0730	2.2300	2.3820	2.8570	2.0720	1.9160	2.3840	2.2110	2.3920	2.5920	2.1270	1.8280	2.1630	1.8610	2.8510	2.4820	2.6820	2.1250	3.2550	3.0570	3.5670	2.8190	2.2200	1.9800	2.1480	2.1000	2.0620	2.1310	2.4600	3.0870	3.3180	1.6850	1.7600	2.5030	2.6770	2.8640	2.8660	4.2380	4.1630	3.1580	1.6310	1.6570	1.2730	1.2420	1.4060	1.6860	3.2620	3.5760	3.1900	3.0240	3.3310	3.4600	2.5940	2.2500	1.8960	2.3950	3.0200	2.8540	2.4880	3.0800	3.1270	1.7530	2.3950	1.4970	2.6480	1.6550	2.8520	4.6110	4.9550	4.4390	1.3730	2.1560	1.6600	1.1220	1.3010	1.5230	3.5750	2.8900	2.8040	2.3370	2.8590	3.8730	2.2800	2.2510	2.1620	2.7050	2.9820	2.6980	2.7570	2.8730	1.0260	1.2770	2.3360	2.6090	1.9150	1.9970	2.3520	2.6550	2.8700	3.7080	1.4820	1.5110	1.5410	0.9930	1.7360	1.9680	2.5470	3.1070	3.1740	4.2740	4.4150	3.7880	2.0890	1.8780	0.6400	2.0130	1.6230	2.8630	2.3170	3.2890	3.0380
Phosphatidylinositol(18:1/20:4)	15.9000	17.1910	15.4150	14.4590	15.1240	16.9430	15.0200	18.0060	17.7790	14.8110	18.6770	18.4430	15.4220	15.9170	16.9920	13.0960	16.4520	17.7630	15.7820	18.1570	17.0760	14.0310	18.2590	17.6280	13.6010	14.5530	14.8030	17.5400	18.5360	16.0140	15.0810	14.6670	14.6460	14.1660	15.8220	14.8740	15.5680	16.0790	14.9330	14.5100	16.9690	16.3820	15.1980	15.4900	15.1920	11.1830	15.1080	11.8860	16.5130	18.8880	17.1800	10.9880	13.5860	11.7570	16.1800	12.6970	17.5250	14.3450	16.3110	13.6990	9.4300	10.4160	10.8770	15.9250	15.6490	16.3080	13.7790	13.0820	16.9670	10.3590	13.3440	10.1750	12.4150	12.3970	13.8050	15.9720	17.6530	19.3570	9.1060	11.1970	10.9840	4.1480	5.6330	3.9810	15.8860	16.2170	18.1320	14.5720	16.5450	17.1020	7.1950	8.2630	7.6640	12.1480	11.1000	11.0120	15.1000	15.7360	12.3080	9.8320	12.1360	11.8080	11.3520	10.5410	12.6600	14.8430	13.2690	13.2240	7.5940	8.8470	7.6210	5.9990	5.8920	6.9760	13.8180	13.9900	12.5840	12.5910	14.1980	11.8730	12.8880	14.4790	18.5200	13.6640	14.1010	17.3030	15.8080	16.1780	17.5170	9.9500	12.5040	14.0810	11.1090	12.5860	13.5650	13.0300	17.2260	16.9350	10.0830	13.4510	13.8620	4.6680	5.6850	4.6130	12.4790	16.3390	17.9800	14.5700	16.4670	15.3900
Phosphatidylinositol(18:1/20:5)	1.6870	1.7940	2.1940	2.2290	1.5550	2.4490	1.7270	1.8310	1.8610	1.9060	1.9220	2.3630	1.7080	1.7570	3.0290	1.6790	2.0020	1.6760	1.9930	2.4850	2.9310	1.6690	2.5750	2.1960	1.5620	1.6490	1.5570	2.2390	2.3230	1.5650	2.0620	1.5100	1.9500	1.9370	1.3560	2.1720	2.1090	1.8300	2.0760	2.0390	1.8020	2.0320	1.8410	1.1740	2.2500	1.5090	1.9950	2.4880	2.5830	2.3930	2.2130	1.6730	1.5530	1.8980	1.4250	1.7290	1.9800	1.9860	2.3390	2.1710	0.3960	0.6720	1.0950	1.4480	1.4120	1.4760	2.0580	1.2920	1.8580	1.2880	0.8290	1.2730	1.1470	1.5710	0.9780	2.0990	2.1150	1.9900	0.9640	1.6720	1.3660	0.5920	0.3190	0.7580	1.7040	2.2540	1.9030	1.1410	2.0580	1.9200	0.8090	0.5810	1.0910	1.2610	1.4260	1.1290	1.9010	2.0420	1.1200	0.6060	1.5460	2.2100	0.9390	1.4860	1.1240	1.9810	1.7430	1.7600	0.7550	0.8850	1.2140	0.2960	0.2680	0.4770	1.4230	1.6520	1.5370	1.5090	1.9280	2.0520	1.3240	1.8010	2.1900	1.3450	1.2870	2.6690	1.5680	1.7480	2.9280	1.0540	1.4240	1.7600	1.0880	1.4110	1.4050	1.8120	2.2940	2.0000	1.5060	1.8530	2.3320	0.5530	0.6090	0.6400	1.8010	1.7910	1.6770	1.0240	1.8760	2.1190
MS_METABOLITE_DATA_END
#METABOLITES
METABOLITES_START
metabolite_name	pubchem_id	inchi_key	kegg_id	other_id	other_id_type	ri	ri_type	moverz_quant	
Phosphatidylinositol(16:0/18:1)									
Phosphatidylinositol(16:0/20:3 n-6)									
Phosphatidylinositol(16:0/20:4)									
Phosphatidylinositol(16:1/18:1)									
Phosphatidylinositol(18:0/20:3 n-6)									
Phosphatidylinositol(18:0/20:4)									
Phosphatidylinositol(18:0/22:5)									
Phosphatidylinositol(18:0/22:6)									
Phosphatidylinositol(18:1/18:1)									
Phosphatidylinositol(18:1/20:3 n-6)									
Phosphatidylinositol(18:1/20:4)									
Phosphatidylinositol(18:1/20:5)									
METABOLITES_END
#END