#METABOLOMICS WORKBENCH tnuriel_20210602_131536_mwtab.txt DATATRACK_ID:2670 STUDY_ID:ST001820 ANALYSIS_ID:AN002954 PROJECT_ID:000000
VERSION             	1
CREATED_ON             	June 7, 2021, 12:36 pm
#PROJECT
PR:PROJECT_TYPE                  	Lipidomics analysis
PR:PROJECT_SUMMARY               	Apolipoprotein E ε4 (APOE4) is the primary genetic risk factor for the
PR:PROJECT_SUMMARY               	late-onset form of Alzheimer's disease (AD). Although the reason for this
PR:PROJECT_SUMMARY               	association is not completely understood, researchers have uncovered numerous
PR:PROJECT_SUMMARY               	effects of APOE4 expression on AD-relevant brain processes, including amyloid
PR:PROJECT_SUMMARY               	beta (Aβ) accumulation, lipid metabolism, endosomal-lysosomal processing and
PR:PROJECT_SUMMARY               	bioenergetics. In this study, we aimed to determine the effect of APOE4 allelic
PR:PROJECT_SUMMARY               	dosage on regional brain lipid composition in aged mice, as well as in cultured
PR:PROJECT_SUMMARY               	neurons. We performed a targeted lipidomic analysis on the entorhinal cortex
PR:PROJECT_SUMMARY               	(EC) and primary visual cortex (PVC) from 14–15 month-old APOE3/3, APOE3/4,
PR:PROJECT_SUMMARY               	and APOE4/4 targeted replacement mice, as well as on WT neurons cultured with
PR:PROJECT_SUMMARY               	conditioned media from APOE3/3 or APOE4/4 astrocytes. Our results reveal that
PR:PROJECT_SUMMARY               	the EC possesses increased susceptibility to APOE4-associated lipid alterations
PR:PROJECT_SUMMARY               	compared to the PVC. In the EC, APOE4 expression showed a dominant effect in
PR:PROJECT_SUMMARY               	decreasing diacylglycerol (DAG) levels, and a semi-dominant additive effect in
PR:PROJECT_SUMMARY               	the upregulation of multiple ceramide, glycosylated sphingolipid and
PR:PROJECT_SUMMARY               	bis(monoacylglycerol)phosphate (BMP) species, lipids known to accumulate as a
PR:PROJECT_SUMMARY               	result of endosomal-lysosomal dysfunction and defective lysosomal clearance.
PR:PROJECT_SUMMARY               	Neurons treated with conditioned media from APOE4 vs. APOE3 astrocytes also
PR:PROJECT_SUMMARY               	showed similar alterations of DAG and BMP species as those observed in the mouse
PR:PROJECT_SUMMARY               	EC. Our results suggest that APOE4 expression differentially modulates regional
PR:PROJECT_SUMMARY               	and neuronal lipid signatures, which may underlie the increased susceptibility
PR:PROJECT_SUMMARY               	of EC-localized neurons to AD pathology.
PR:INSTITUTE                     	Columbia University
PR:FIRST_NAME                    	Tal
PR:ADDRESS                       	630 W 168th St., P&S 12-430
PR:EMAIL                         	tn2283@cumc.columbia.edu
PR:PHONE                         	2123045683
PR:PROJECT_TITLE                 	APOE4-associated differences in lipidomics signatures in mouse brain and
PR:PROJECT_TITLE                 	cultured neurons
PR:LAST_NAME                     	Nuriel
#STUDY
ST:STUDY_TITLE                   	WT neurons treated with APOE3/3 and APOE4/4 ACM
ST:STUDY_SUMMARY                 	We performed a targeted lipidomic analysis on WT neurons treated with astrocyte
ST:STUDY_SUMMARY                 	conditioned media (ACM) from APOE3/3 or APOE4/4 astrocytes.
ST:INSTITUTE                     	Columbia University
ST:LAST_NAME                     	Nuriel
ST:FIRST_NAME                    	Tal
ST:ADDRESS                       	630 W 168th St., P&S 12-430
ST:EMAIL                         	tn2283@cumc.columbia.edu
ST:PHONE                         	2123045683
#SUBJECT
SU:SUBJECT_TYPE                  	Cultured cells
SU:SUBJECT_SPECIES               	Mus musculus
SU:TAXONOMY_ID                   	10090
SU:GENDER                        	Not applicable
#FACTORS
#SUBJECT_SAMPLE_FACTORS:         	SUBJECT(optional)[tab]SAMPLE[tab]FACTORS(NAME:VALUE pairs separated by |)[tab]Raw file names and additional sample data
SUBJECT_SAMPLE_FACTORS           	-	1	Condition:No ACM	
SUBJECT_SAMPLE_FACTORS           	-	2	Condition:No ACM	
SUBJECT_SAMPLE_FACTORS           	-	3	Condition:No ACM	
SUBJECT_SAMPLE_FACTORS           	-	4	Condition:No ACM	
SUBJECT_SAMPLE_FACTORS           	-	5	Condition:No ACM	
SUBJECT_SAMPLE_FACTORS           	-	6	Condition:No ACM	
SUBJECT_SAMPLE_FACTORS           	-	7	Condition:APOE3/3 ACM	
SUBJECT_SAMPLE_FACTORS           	-	8	Condition:APOE3/3 ACM	
SUBJECT_SAMPLE_FACTORS           	-	9	Condition:APOE3/3 ACM	
SUBJECT_SAMPLE_FACTORS           	-	10	Condition:APOE3/3 ACM	
SUBJECT_SAMPLE_FACTORS           	-	11	Condition:APOE3/3 ACM	
SUBJECT_SAMPLE_FACTORS           	-	12	Condition:APOE3/3 ACM	
SUBJECT_SAMPLE_FACTORS           	-	13	Condition:APOE4/4 ACM	
SUBJECT_SAMPLE_FACTORS           	-	14	Condition:APOE4/4 ACM	
SUBJECT_SAMPLE_FACTORS           	-	15	Condition:APOE4/4 ACM	
SUBJECT_SAMPLE_FACTORS           	-	16	Condition:APOE4/4 ACM	
SUBJECT_SAMPLE_FACTORS           	-	17	Condition:APOE4/4 ACM	
SUBJECT_SAMPLE_FACTORS           	-	18	Condition:APOE4/4 ACM	
#COLLECTION
CO:COLLECTION_SUMMARY            	Astrocyte conditioned media (ACM) was obtained from immortalized astrocyte cell
CO:COLLECTION_SUMMARY            	lines (a gift from Dr. David Holtzman) that were originally generated from
CO:COLLECTION_SUMMARY            	primary astrocytes from P1-2 pups of APOE targeted replacement mice (42). The
CO:COLLECTION_SUMMARY            	immortalized astrocytes were conditioned with Neurobasal media supplemented with
CO:COLLECTION_SUMMARY            	B27, Glutamax-I, Normocin and 1% penicillin/streptomycin for 24 hours. This ACM
CO:COLLECTION_SUMMARY            	was then collected, stored at -80ºC, and thawed prior to use. WT primary
CO:COLLECTION_SUMMARY            	cortical neuronal cultures were obtained from embryonic day 17 (E17) C57Bl/6
CO:COLLECTION_SUMMARY            	embryos. Briefly, pregnant mice were euthanized by cervical dislocation and the
CO:COLLECTION_SUMMARY            	embryo brains extracted. The meninges were carefully stripped off and the
CO:COLLECTION_SUMMARY            	cortices dissected out. The cortices were then enzymatically dissociated in
CO:COLLECTION_SUMMARY            	0.25% Trypsin-EDTA and resuspended in Neurobasal media supplemented with B27,
CO:COLLECTION_SUMMARY            	Glutamax-I, Normocin and 1% penicillin/streptomycin. Dissociated cells were
CO:COLLECTION_SUMMARY            	counted and 300K neurons per well were plated directly into ACM in poly-D-lysine
CO:COLLECTION_SUMMARY            	(PDL)-coated 6-well plates. ACM-treated neurons were then incubated at 37⁰C
CO:COLLECTION_SUMMARY            	for 7 days in a humidified chamber with 5% CO2, with 50% media exchange (with
CO:COLLECTION_SUMMARY            	newly thawed ACM) once every 3 days.
CO:SAMPLE_TYPE                   	Neurons
#TREATMENT
TR:TREATMENT_SUMMARY             	WT neurons were incubated for 7 days in either no ACM, APOE3/3 ACM, or APOE4/4
TR:TREATMENT_SUMMARY             	ACM.
#SAMPLEPREP
SP:SAMPLEPREP_SUMMARY            	Lipid and small-molecule metabolite extraction was performed using a methyl
SP:SAMPLEPREP_SUMMARY            	tert-butyl ether (MTBE)/methanol extraction protocol. Briefly, harvested neurons
SP:SAMPLEPREP_SUMMARY            	were homogenized in ice-cold methanol. Following homogenization, samples were
SP:SAMPLEPREP_SUMMARY            	incubated in 1200 ul of MTBE for 1 hr at room temperature to separate
SP:SAMPLEPREP_SUMMARY            	organic-soluble lipids from aqueous-soluble lipids and other small-molecules.
SP:SAMPLEPREP_SUMMARY            	Finally, 360 ul of ultrapure water was added (for a final ratio of 3:1:0.9
SP:SAMPLEPREP_SUMMARY            	MTBE:methanol:water) to resolve the two liquid phases, and each samples were
SP:SAMPLEPREP_SUMMARY            	centrifuged at 10,000 x g for 10 min. For this experiment, the upper organic
SP:SAMPLEPREP_SUMMARY            	phase was collected from each sample and stored in a separate tube, and the
SP:SAMPLEPREP_SUMMARY            	remaining protein pellets were resuspended in 25 mM ammonium bicarbonate, pH 8,
SP:SAMPLEPREP_SUMMARY            	with 2.5% SDS. A BCA protein assay was performed on each protein fraction, and
SP:SAMPLEPREP_SUMMARY            	the organic phase was normalized to their protein concentration equivalent with
SP:SAMPLEPREP_SUMMARY            	100% methanol. All samples were then stored at -80°C prior to analysis.
#CHROMATOGRAPHY
CH:CHROMATOGRAPHY_SUMMARY        	Reverse phase
CH:CHROMATOGRAPHY_TYPE           	Reversed phase
CH:INSTRUMENT_NAME               	Agilent 1260
CH:COLUMN_NAME                   	Agilent Eclipse XDB-C18 (100 x 3.0mm)
#ANALYSIS
AN:ANALYSIS_TYPE                 	MS
#MS
MS:INSTRUMENT_NAME               	Agilent 6490 QQQ
MS:INSTRUMENT_TYPE               	Triple quadrupole
MS:MS_TYPE                       	ESI
MS:ION_MODE                      	NEGATIVE
MS:MS_COMMENTS                   	Lipid profiling was performed using an Agilent 1260 HPLC coupled to an Agilent
MS:MS_COMMENTS                   	6490 triple quadrupole (QQQ) mass spectrometer (41). Each sample was run through
MS:MS_COMMENTS                   	three separate chromatographic conditions (reverse-phase negative mode,
MS:MS_COMMENTS                   	reverse-phase positive mode and normal-phase positive mode) for the effective
MS:MS_COMMENTS                   	quantification of over 337 distinct lipids from over 28 lipid subclasses, as
MS:MS_COMMENTS                   	previously described (41). Individual lipid species were measured by multiple
MS:MS_COMMENTS                   	reaction monitoring transitions.
#MS_METABOLITE_DATA
MS_METABOLITE_DATA:UNITS	area under the curve
MS_METABOLITE_DATA_START
Samples	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Factors	Condition:No ACM	Condition:No ACM	Condition:No ACM	Condition:No ACM	Condition:No ACM	Condition:No ACM	Condition:APOE3/3 ACM	Condition:APOE3/3 ACM	Condition:APOE3/3 ACM	Condition:APOE3/3 ACM	Condition:APOE3/3 ACM	Condition:APOE3/3 ACM	Condition:APOE4/4 ACM	Condition:APOE4/4 ACM	Condition:APOE4/4 ACM	Condition:APOE4/4 ACM	Condition:APOE4/4 ACM	Condition:APOE4/4 ACM
Sulf d18:0/16:1	0.02178	0.02610	0.02254	0.01970	0.01416	0.02242	0.09882	0.04437	0.06011	0.09331	0.08364	0.02823	0.03542	0.03133	0.06669	0.05003	0.07384	0.06838
Sulf d18:0/18:1	0.03391	0.02596	0.02222	0.02586	0.01477	0.02333	0.14554	0.07056	0.08994	0.08910	0.09444	0.05286	0.06711	0.04523	0.06558	0.06596	0.09110	0.07453
Sulf d18:0/22:1	0.00857	0.01081	0.00482	0.00764	0.00130	0.00295	0.04175	0.02514	0.02227	0.04526	0.02594	0.01910	0.02365	0.00638	0.01624	0.02028	0.03653	0.01651
Sulf d18:0/24:1	0.01678	0.01901	0.01344	0.01895	0.00800	0.00405	0.06294	0.02140	0.02627	0.05278	0.03747	0.01466	0.02644	0.02513	0.04779	0.03747	0.03268	0.02881
Sulf d18:1/16:0	0.02076	0.02595	0.02192	0.01967	0.01293	0.02200	0.09775	0.05007	0.05991	0.09307	0.08330	0.02700	0.03550	0.03257	0.06645	0.05060	0.07185	0.06783
Sulf d18:1/18:0	0.03391	0.02596	0.02222	0.02586	0.01477	0.02333	0.14554	0.07056	0.08994	0.08910	0.09444	0.05286	0.06711	0.04523	0.06558	0.06596	0.09110	0.07474
Sulf d18:1/22:0	0.00843	0.00824	0.00446	0.00679	0.00198	0.00237	0.04172	0.02528	0.02163	0.04553	0.02503	0.01938	0.02286	0.00676	0.01750	0.02015	0.03502	0.01606
Sulf d18:1/24:0	0.01584	0.01906	0.01383	0.01897	0.00805	0.00394	0.06296	0.01940	0.02635	0.05074	0.03749	0.01475	0.02692	0.02603	0.04790	0.03751	0.03328	0.02983
Sulf d18:1/24:1	0.01661	0.00779	0.01424	0.01517	0.00843	0.00836	0.05816	0.02822	0.03337	0.05102	0.04302	0.01138	0.03215	0.03117	0.03437	0.03645	0.05268	0.03561
GM3 d18:0/16:1	0.16536	0.13241	0.01518	0.00000	0.06113	0.00000	0.50902	0.17189	0.15503	0.20851	0.19037	0.00000	0.09180	0.43940	0.41677	0.22274	0.30514	0.00000
GM3 d18:0/18:1	0.18888	0.21591	0.01293	0.00000	0.07404	0.00000	0.26061	0.20600	0.14213	0.32202	0.22509	0.00000	0.07813	0.06981	0.01650	0.20786	0.25434	0.01736
GM3 d18:0/20:1	0.02143	0.04017	0.01571	0.00000	0.03861	0.00000	0.07066	0.05640	0.01765	0.05181	0.03155	0.00000	0.00000	0.04373	0.01487	0.05715	0.03131	0.00000
PA 30:0	0.04720	0.04111	0.05440	0.07527	0.03078	0.05022	0.03364	0.01472	0.02819	0.01460	0.01722	0.01902	0.03942	0.05134	0.04775	0.04777	0.04829	0.05206
PA 32:0	0.18693	0.20549	0.11911	0.21444	0.10471	0.17301	0.08614	0.04784	0.10933	0.03109	0.05154	0.06429	0.15530	0.16360	0.18523	0.17918	0.23259	0.23829
PA 32:1	0.04154	0.03921	0.03588	0.06503	0.04841	0.05738	0.04770	0.02117	0.03738	0.02388	0.03249	0.01714	0.04466	0.02463	0.06669	0.08283	0.06345	0.07258
PA 34:0	0.09367	0.05357	0.05117	0.07844	0.04037	0.07645	0.03899	0.02285	0.02206	0.05448	0.03077	0.02006	0.10035	0.11461	0.10789	0.09009	0.12124	0.14534
PA 34:1	0.14004	0.12616	0.11770	0.18576	0.09051	0.16266	0.08984	0.04988	0.08090	0.08987	0.06266	0.04792	0.11311	0.11416	0.10894	0.10893	0.23742	0.10571
PA 36:1	0.07744	0.08762	0.07110	0.08978	0.04129	0.09182	0.04364	0.01536	0.02085	0.01535	0.03817	0.01552	0.08110	0.05085	0.04779	0.08366	0.06604	0.06716
PA 38:3	0.05763	0.03925	0.04457	0.05359	0.01417	0.05199	0.03392	0.02907	0.02197	0.01558	0.05006	0.00690	0.05834	0.05187	0.05686	0.08500	0.08933	0.03376
PA 38:4	0.34122	0.21709	0.20048	0.40374	0.18958	0.30532	0.09320	0.03934	0.04517	0.05653	0.05422	0.03097	0.08880	0.08630	0.08313	0.12297	0.15401	0.09682
PA 40:6	0.20219	0.17635	0.15647	0.20676	0.11544	0.21609	0.04190	0.01473	0.04253	0.02474	0.06737	-0.02641	0.00675	0.07688	0.09173	0.14156	0.14174	0.09032
PE 32:0	1.06664	0.88789	0.48382	0.53443	0.70743	0.59690	0.48129	0.58791	0.40151	0.34958	0.21931	0.31224	0.42918	0.27506	0.41268	0.25234	0.87412	0.29372
PE 32:1	0.48919	0.61024	0.70761	0.87481	0.40020	0.87218	2.50472	1.87772	1.19099	1.16905	1.76460	0.94376	1.13982	1.13654	1.14872	0.84786	2.27668	1.79848
PE 34:0	1.38564	1.35751	0.97390	1.39924	0.63739	1.49473	1.04419	0.71793	0.65137	0.74834	1.05027	0.43665	1.13261	0.70425	1.27957	0.55035	1.63836	0.36627
PE 34:1	4.68626	4.76368	3.43110	3.76293	2.49500	5.86148	9.55072	6.19449	4.63873	4.82925	6.41498	6.53855	6.96706	4.00249	6.01136	6.86732	9.50434	7.52006
PE 34:2	0.83653	1.39548	0.97996	0.83015	0.57844	0.94845	2.75284	1.86994	2.15022	2.14145	2.63379	2.54579	1.60444	1.51031	1.07724	1.99306	2.59011	1.55380
PE 36:0	6.69786	6.26697	4.94471	6.52188	3.91750	6.30607	4.90132	3.38142	3.42889	3.63958	4.96825	3.21767	5.30447	3.00865	4.71447	4.28327	7.05413	5.16064
PE 36:1	3.19337	2.88991	2.72137	2.75784	1.21012	4.21048	2.85899	1.42119	1.88134	2.56724	2.60341	2.40802	3.50345	3.89412	2.57475	4.20282	3.83624	3.38513
PE 36:2	1.64010	1.16086	1.81787	1.29647	0.80232	2.61375	5.40706	3.23668	3.44408	4.13242	4.80897	4.09672	4.58322	3.07235	2.98168	3.26073	4.72255	2.06573
PE 36:3	1.01107	0.90707	0.86977	1.27287	0.88848	1.54664	2.06407	2.06801	1.06646	1.62313	2.29992	1.30231	1.05914	1.92735	1.72460	0.71958	2.13392	1.67058
PE 36:4	3.46171	2.99566	2.96711	1.66899	1.12819	3.03808	1.91926	1.77292	1.35238	0.83558	1.78060	1.40466	1.51117	1.04023	1.44357	0.98489	2.04579	1.41524
PE 38:0	8.65315	8.97058	5.84968	4.88064	4.20942	8.68607	6.01100	3.87728	3.83608	2.85719	5.08554	3.57174	6.79357	3.43270	4.97238	4.63521	8.42460	7.34770
PE 38:1	1.74695	1.78577	1.63931	1.51900	0.79727	2.13280	2.36970	1.51271	1.66306	1.05710	2.07470	1.06283	2.30547	1.57774	3.29190	1.39093	2.95948	2.27667
PE 38:2	0.28393	0.39509	0.22618	0.18427	0.16604	0.54189	1.55865	0.46116	0.54547	0.82868	1.47274	0.57045	1.13394	0.96339	1.11532	1.40959	1.41714	0.69211
PE 38:3	2.29806	2.81382	1.78575	1.91411	1.72707	2.00521	7.31934	4.68691	3.93894	3.69906	4.84682	3.96288	6.79853	3.96711	5.13932	6.64927	10.35364	5.59419
PE 38:4	16.09949	19.88285	15.18440	14.07046	7.95433	22.69379	8.89951	6.00214	6.35580	4.14388	7.76095	5.94598	10.06530	7.11405	7.84119	8.98000	9.74166	10.81876
PE 38:5	3.00934	3.01747	3.23121	2.90933	1.43176	3.92621	2.21836	1.01307	1.69490	1.60918	2.58337	0.84096	2.09471	1.42237	1.74975	1.55550	2.18105	1.38329
PE 38:6	1.68701	1.80978	2.41750	1.27760	1.21844	2.01310	1.50057	0.68270	0.84797	0.66190	1.20572	0.48977	0.72851	1.03733	1.62298	0.57732	1.22518	0.70413
PE 40:4	1.83278	2.37795	1.05578	1.11349	1.36609	2.15200	0.93661	0.68701	0.27070	0.29707	0.67674	0.89744	0.95990	1.00310	0.86510	0.55734	1.44349	0.85892
PE 40:5	2.13444	2.86849	1.32707	2.15981	1.38101	2.58557	1.28556	0.94411	0.73662	0.92368	0.57325	0.65085	0.91961	0.51572	0.41211	0.38900	1.14171	1.15757
PE 40:6	4.46559	2.71011	3.14106	2.00442	2.87780	3.39998	3.62624	1.43164	1.26759	1.23159	2.53472	1.50570	2.98200	1.33444	1.97739	2.17658	3.18954	2.48887
PE 40:7	0.80293	0.68902	0.67141	0.71974	0.40492	0.70012	0.91008	0.33458	0.76134	0.32402	0.92985	0.56756	1.35447	0.29267	1.16421	0.31053	0.92693	0.55109
PEp 32:0	0.94063	0.55370	0.94234	0.89001	0.53892	0.53695	0.57561	0.35903	0.43363	0.19700	0.60305	0.72993	0.57484	0.38804	0.68281	0.46448	0.88434	0.21142
PEp 32:1	0.13434	0.03985	0.02447	0.11588	0.00000	0.19395	0.58805	0.51233	0.26932	0.52315	1.31574	0.50916	0.85644	0.53559	0.96339	0.54408	0.73997	0.92569
PEp 34:0	1.29279	0.88550	0.35510	0.83815	0.63650	1.15485	0.74469	0.84440	0.82148	1.18954	0.73737	0.86024	1.30395	0.79175	0.68820	0.80365	1.20669	0.74089
PEp 34:1	1.93540	1.86345	1.10976	1.31027	0.95834	1.49022	4.74001	2.81850	3.10709	2.73732	3.38749	2.03583	3.45700	2.05010	3.16236	2.81891	3.94587	4.24755
PEp 34:2	0.56797	0.11884	0.06345	0.24287	0.26256	0.51175	1.03143	1.23024	0.75747	0.83318	0.92300	0.37876	0.81178	0.76599	1.00663	0.58765	0.67858	0.78713
PEp 36:0	0.10136	0.04025	0.25733	0.18692	0.14536	0.16956	0.76042	1.26204	0.56807	0.27324	0.57882	0.59063	0.37171	0.42728	0.03845	0.29732	0.98921	0.67134
PEp 36:1	0.31665	0.35913	0.52487	0.14591	0.41888	0.58051	1.96644	0.77254	1.25478	1.28963	1.81195	0.86915	1.16986	1.14482	1.11901	1.50518	1.78749	1.55358
PEp 36:2	0.34698	0.35723	0.28060	0.24883	0.25701	0.37772	2.08690	1.45644	0.90530	1.49771	1.44864	0.65392	1.06066	0.96531	1.15071	1.10569	1.63147	1.72696
PEp 36:3	0.78085	0.52319	0.62386	0.31484	0.52782	0.31619	2.49629	1.31330	1.35791	1.89401	3.06115	0.97797	1.32496	0.81885	1.79315	0.90093	2.00368	0.57987
PEp 36:4	2.57795	2.87066	2.07689	2.77215	2.17572	3.11823	1.55154	1.36649	1.42442	1.08869	1.62990	1.62204	1.29467	0.98603	1.70531	1.71469	2.53383	1.06958
PEp 38:0	0.07469	0.25845	0.19876	0.05768	0.08891	0.01233	0.52884	0.39598	0.33051	0.07917	0.24018	0.14492	0.64347	0.15633	0.52090	0.36469	0.35545	0.72621
PEp 38:3	1.03943	1.09741	1.28108	1.21595	0.66166	1.15911	2.57892	2.92141	1.53260	2.01608	3.55882	1.69151	2.40095	2.65591	2.42127	2.53167	2.30589	2.29365
PEp 38:4	5.58973	6.38806	5.07224	6.64700	3.42215	6.42144	3.77191	2.89263	2.07761	3.21393	2.89758	1.88090	3.64686	2.67902	3.52747	2.90663	4.42303	2.71245
PEp 38:5	3.48745	3.58787	2.82078	3.55951	1.56480	3.42129	2.59424	1.21092	1.71245	1.43069	1.56791	1.24828	1.70150	1.46923	1.90416	1.82480	1.88885	1.69486
PEp 38:6	6.69801	6.26847	4.94471	6.56278	3.91681	6.30955	4.90107	3.38138	3.42959	3.70056	4.96766	3.21208	5.30479	3.01016	4.71118	4.28357	6.97476	5.16775
PEp 40:4	3.23779	3.05066	2.82390	2.38323	1.59945	2.80137	1.58364	1.24163	0.56925	0.60432	1.41261	1.20676	1.83626	0.88930	1.65158	2.19038	3.61430	1.86237
PEp 40:5	3.51543	2.43140	3.15080	1.58040	1.22090	1.99554	1.17964	1.10303	1.11178	1.05723	0.97562	1.25522	1.33568	0.89761	0.97925	1.12664	2.83196	1.21264
PEp 40:6	8.65324	8.96987	6.53409	4.88128	4.20956	8.68564	6.00999	3.87687	3.83807	2.85593	5.08600	3.56675	6.79269	3.43315	4.92548	4.63482	8.42661	7.34623
PEp 40:7	1.74836	1.63182	0.08195	1.17612	0.65039	1.58851	2.01728	1.42329	0.10135	1.01044	1.89010	0.97520	2.38969	1.33924	3.25908	0.99707	2.80903	2.08332
PS 32:0	0.23374	0.22176	0.16784	0.10940	0.19047	0.10568	0.15239	0.05736	0.08246	0.05069	0.08549	0.03586	0.06751	0.03723	0.06579	0.08388	0.08821	0.06986
PS 32:1	0.04481	0.04274	0.06383	0.03841	0.03296	0.01133	0.24129	0.11379	0.13409	0.12467	0.13397	0.04708	0.05778	0.09434	0.13112	0.05808	0.18343	0.12812
PS 34:0	0.55446	0.52650	0.47764	0.37808	0.39488	0.21760	0.29640	0.18372	0.21375	0.25182	0.25327	0.08061	0.18844	0.14945	0.26102	0.25782	0.38749	0.25562
PS 34:1	0.56004	0.73478	0.75098	0.43434	0.65567	0.40764	1.75404	0.77437	1.01513	1.31875	1.46534	0.42421	0.93134	0.92057	1.58404	1.09948	1.78904	1.25726
PS 34:2	0.06282	0.06658	0.05703	0.08083	0.06119	0.03457	0.26877	0.16884	0.18776	0.20182	0.22889	0.05247	0.14753	0.11488	0.26793	0.16990	0.28860	0.18672
PS 36:0	0.12078	0.11383	0.12182	0.05880	0.11967	0.06664	0.32988	0.16892	0.19687	0.22865	0.25842	0.07509	0.16147	0.22669	0.29776	0.19614	0.35174	0.21304
PS 36:1	0.89877	0.97208	1.04984	0.71815	0.82594	0.65019	2.39810	1.31390	1.72766	2.10617	1.98345	0.68734	1.49719	1.28934	2.09525	1.87049	2.92793	2.09749
PS 36:2	0.28019	0.25662	0.33229	0.26375	0.19653	0.14421	1.03531	0.45093	0.64127	0.70457	0.95578	0.29910	0.51879	0.46113	0.75817	0.66455	0.96370	0.57131
PS 36:3	0.09929	0.12740	0.10514	0.09892	0.09651	0.13187	0.21104	0.15863	0.13209	0.16978	0.21287	0.03847	0.09031	0.07214	0.19439	0.11676	0.22688	0.12003
PS 36:4	0.08966	0.09458	0.10596	0.08853	0.08952	0.04718	0.06861	0.02789	0.07313	0.04656	0.03732	0.00957	0.04074	0.05059	0.06197	0.05255	0.06012	0.03615
PS 38:1	0.01955	0.04600	0.05410	0.02831	0.02137	0.01512	0.13358	0.08061	0.07799	0.13427	0.16678	0.02975	0.08281	0.06017	0.16320	0.13795	0.19835	0.12006
PS 38:2	0.13635	0.10193	0.09725	0.11636	0.11696	0.11697	0.44061	0.20583	0.21965	0.47392	0.30617	0.10481	0.30067	0.22585	0.45575	0.40975	0.51124	0.31418
PS 38:3	0.72381	0.79734	0.95511	0.58347	0.69860	0.54385	1.47294	0.74256	0.94226	1.30788	1.30284	0.35524	0.99993	0.75463	1.48194	1.12551	1.93353	1.11947
PS 38:4	1.97372	2.05747	2.29131	1.44803	1.62090	1.35072	1.12150	0.58772	0.69147	0.94118	0.91154	0.33334	0.88316	0.74395	1.13127	0.85857	1.58519	0.96180
PS 38:5	0.19984	0.20061	0.28982	0.15875	0.21094	0.14443	0.15048	0.06580	0.07661	0.11436	0.11657	0.06340	0.10215	0.06773	0.14502	0.09325	0.11074	0.10266
PS 38:6	0.09289	0.07010	0.15840	0.08576	0.06097	0.08365	0.12769	0.05508	0.09010	0.05695	0.05896	0.04987	0.08171	0.06262	0.10112	0.08830	0.10365	0.11068
PS 40:4	2.43188	2.78755	2.82712	1.82736	2.04647	1.72196	0.94258	0.41395	0.54531	0.72012	0.71221	0.31212	0.78309	0.65563	1.02166	0.74441	1.19761	0.80308
PS 40:5	2.73622	3.33853	3.59959	2.09612	2.60250	2.20276	1.71745	0.94904	1.05692	1.37260	1.30134	0.44416	1.18353	0.99581	1.84688	1.40290	2.49218	1.41235
PS 40:6	4.21420	4.36258	5.34879	3.37124	3.83434	3.19142	5.35182	2.69517	3.47211	4.08321	4.38683	1.50320	4.09914	3.34288	5.45626	4.73918	7.37454	4.27436
PS 40:7	0.10691	0.11191	0.12500	0.08892	0.10071	0.07949	0.30886	0.21334	0.21710	0.22397	0.33590	0.13552	0.19855	0.20022	0.23601	0.27906	0.38497	0.22621
PS 42:5	0.29089	0.34769	0.26115	0.22553	0.23829	0.25170	0.19467	0.10723	0.14705	0.16509	0.16427	0.04579	0.16187	0.11320	0.17901	0.14535	0.19835	0.17962
PS 42:6	0.28361	0.29494	0.37644	0.17992	0.27199	0.22463	0.25571	0.07838	0.14639	0.13400	0.18991	0.09379	0.09425	0.10415	0.22747	0.15514	0.19059	0.11572
PS 42:7	0.06731	0.03883	0.07698	0.04302	0.07546	0.05212	0.10627	0.09223	0.08885	0.06505	0.09963	0.06309	0.08011	0.08558	0.13304	0.08026	0.14749	0.12126
PI 32:1	0.04660	0.04401	0.00847	0.02157	0.03050	0.00000	0.07424	0.00267	0.07386	0.06943	0.03966	0.02383	0.01373	0.01234	0.04038	0.03004	0.06565	0.03259
PI 34:1	0.11656	0.06778	0.06911	0.06583	0.05148	0.01944	0.16273	0.10872	0.15852	0.11791	0.12686	0.03453	0.08231	0.16156	0.11224	0.10533	0.11050	0.04015
PI 34:2	0.01462	0.05366	0.09328	0.04473	0.05417	0.00000	0.14846	0.04470	0.15622	0.26361	0.04652	0.03791	0.05955	0.05889	0.09137	0.07538	0.15163	0.01396
PI 36:1	0.03620	0.01109	0.01283	0.03203	0.02006	0.00000	0.07520	0.06061	0.08334	0.11024	0.04338	0.00000	0.02121	0.06257	0.06731	0.08951	0.08038	0.09978
PI 36:2	0.08157	0.07161	0.03919	0.01763	0.00000	0.05469	0.35716	0.19440	0.22201	0.22337	0.21332	0.06106	0.20146	0.26606	0.25236	0.30054	0.23099	0.15462
PI 36:3	0.21717	0.27206	0.17277	0.11479	0.14569	0.15803	1.30006	0.50330	0.87535	0.93166	1.17922	0.19892	0.43483	0.52914	0.75781	0.57509	0.82715	0.89496
PI 36:4	1.23278	1.24322	0.86784	1.01321	0.63073	0.54804	0.94558	0.38467	0.44784	0.58633	0.30176	0.13441	0.23981	0.13651	0.31501	0.35748	0.37487	0.32508
PI 38:2	0.07321	0.04699	0.04707	0.06757	0.06202	0.01052	0.64908	0.37627	0.38694	0.51143	0.56477	0.09448	0.19710	0.29186	0.44313	0.52163	0.47629	0.31879
PI 38:3	1.23833	0.83754	0.82350	0.54996	0.73092	0.28655	4.36673	1.78309	3.46446	3.11103	2.70785	0.54112	1.69120	2.15669	3.42908	3.19790	3.51494	2.38844
PI 38:4	10.33441	7.34077	5.93438	4.17483	5.02716	2.57680	5.42852	2.20432	4.00226	3.89411	3.71605	0.72915	2.55991	3.60937	5.80409	4.36489	4.59648	3.88540
PI 38:5	2.06906	1.68173	1.49697	1.11082	0.99912	0.55697	1.49844	0.56353	1.06870	0.97075	0.86354	0.13139	0.76965	0.76278	1.46255	1.02676	1.14455	1.08898
PI 38:6	0.22652	0.25935	0.19338	0.22943	0.11622	0.12075	0.08548	0.03639	0.07997	0.05263	0.05546	0.07761	0.04414	0.04178	0.03069	0.07983	0.10153	0.06101
PI 40:4	0.08656	0.15519	0.07655	0.05488	0.07568	0.04497	0.08880	0.03591	0.01886	0.03269	0.06835	0.00780	0.04682	0.04059	0.07374	0.02956	0.04791	0.09025
PI 40:5	0.11909	0.15251	0.11656	0.03145	0.01888	0.01537	0.09450	0.10074	0.05624	0.10208	0.02689	0.01875	0.02247	0.02121	0.13724	0.11800	0.10230	0.09706
PI 40:6	0.16192	0.09522	0.03603	0.06966	0.05352	0.03444	0.11560	0.03050	0.09719	0.04105	0.05054	0.00000	0.01085	0.06152	0.08664	0.04871	0.03434	0.13525
PI 40:7	0.05788	0.08102	0.04685	0.08682	0.02150	0.02502	0.04265	0.03161	0.07094	0.01539	0.01277	0.03596	0.01501	0.02013	0.08496	0.06516	0.00894	0.04888
PG 30:0	0.00243	0.00336	0.00245	0.00341	0.00195	0.00358	0.00048	0.00046	0.00037	0.00049	0.00048	0.00032	0.00132	0.00069	0.00151	0.00096	0.00156	0.00138
PG 32:1	0.00647	0.00928	0.00760	0.00683	0.00691	0.00834	0.00454	0.00239	0.00253	0.00333	0.00419	0.00191	0.00598	0.00522	0.00608	0.00784	0.00804	0.00491
PG 34:0	0.01251	0.01186	0.00930	0.01114	0.00652	0.00909	0.00478	0.00265	0.00313	0.00493	0.00276	0.00252	0.00568	0.00322	0.00502	0.00562	0.00719	0.00671
PG 34:1	0.06337	0.06978	0.06439	0.06561	0.05373	0.06004	0.05499	0.03595	0.03291	0.03985	0.04588	0.03024	0.05141	0.04549	0.05529	0.05982	0.07905	0.06032
PG 34:2	0.00517	0.00692	0.00766	0.00735	0.00569	0.00540	0.00210	0.00113	0.00146	0.00241	0.00192	0.00099	0.00106	0.00173	0.00234	0.00235	0.00239	0.00077
PG 36:1	0.00816	0.00883	0.00654	0.00858	0.00564	0.00766	0.00478	0.00370	0.00331	0.00453	0.00469	0.00277	0.00700	0.00515	0.00671	0.00955	0.01072	0.00603
PG 36:2	0.01667	0.02109	0.01879	0.02326	0.01244	0.01961	0.01931	0.01348	0.00957	0.01764	0.01857	0.00857	0.02781	0.02181	0.02284	0.02956	0.03242	0.02628
PG 36:3	0.00214	0.00302	0.00244	0.00422	0.00289	0.00293	0.00121	0.00105	0.00031	0.00105	0.00090	0.00049	0.00141	0.00188	0.00111	0.00134	0.00179	0.00194
PG 36:4	0.01308	0.01445	0.01360	0.01657	0.01079	0.01411	0.00148	0.00062	0.00114	0.00039	0.00124	0.00085	0.00207	0.00110	0.00326	0.00190	0.00310	0.00290
PG 38:4	0.02206	0.02543	0.02526	0.02105	0.01830	0.01995	0.00321	0.00275	0.00270	0.00298	0.00429	0.00160	0.00662	0.00446	0.00581	0.00722	0.00805	0.00656
BMP 32:1	0.06717	0.08588	0.04719	0.06230	0.02749	0.07457	0.03258	0.01377	0.02956	0.01763	0.02369	0.01194	0.04188	0.02216	0.01869	0.03170	0.03894	-0.00022
BMP 34:1	0.03120	0.03667	0.03025	0.04577	0.03160	0.02204	0.24487	0.16399	0.15859	0.18010	0.20265	0.11581	0.18189	0.13349	0.18806	0.14902	0.21922	0.18264
BMP 36:1	0.02846	0.05579	0.02660	0.03587	0.01843	0.05198	0.29793	0.19088	0.24723	0.18926	0.27232	0.15240	0.37742	0.25337	0.36625	0.29007	0.42953	0.38065
BMP 36:2	0.45888	0.51858	0.38202	0.59375	0.36917	0.57581	5.69190	3.75886	3.86403	4.23365	5.17337	2.77252	5.91896	4.19461	5.20513	4.62015	7.04459	5.95157
BMP 38:2	0.01427	0.02021	0.00303	0.01277	0.00927	0.02102	0.23286	0.15304	0.17989	0.16494	0.24714	0.10334	0.28863	0.21094	0.25433	0.24676	0.32559	0.26481
BMP 38:3	0.03584	0.03623	0.03363	0.03186	0.02921	0.05360	0.69081	0.48108	0.47852	0.51155	0.59509	0.32886	0.78004	0.46741	0.68582	0.57683	0.88956	0.83308
BMP 40:7	0.20550	0.24635	0.18205	0.23641	0.15081	0.27188	0.34858	0.21151	0.21517	0.25440	0.27798	0.18572	0.44124	0.30009	0.35718	0.31378	0.50037	0.40275
AcylPG 16:0-34:0	0.00301	0.00444	0.00305	0.00345	0.00166	0.00397	0.00137	0.00136	0.00164	0.00128	0.00109	0.00113	0.00245	0.00172	0.00170	0.00102	0.00223	0.00214
AcylPG 16:0-34:1	0.00606	0.00753	0.00508	0.00627	0.00601	0.00531	0.00530	0.00399	0.00451	0.00405	0.00424	0.00319	0.00649	0.00608	0.00630	0.01052	0.00994	0.00672
AcylPG 16:0-34:2	0.01389	0.01580	0.01064	0.01386	0.00917	0.01187	0.00836	0.00639	0.00595	0.00521	0.00655	0.00368	0.01832	0.01151	0.01261	0.01659	0.01878	0.01166
AcylPG 16:0-36:0	0.00303	0.00344	0.00195	0.00020	0.00152	0.00238	0.00213	0.00155	0.00151	0.00094	0.00143	0.00028	0.00254	0.00229	0.00285	0.00253	0.00380	0.00192
AcylPG 16:0-36:1	0.00312	0.00329	0.00278	0.00318	0.00267	0.00297	0.00303	0.00262	0.00236	0.00195	0.00322	0.00200	0.00514	0.00312	0.00331	0.00573	0.00588	0.00432
AcylPG 16:0-36:2	0.03009	0.02933	0.02189	0.02414	0.01476	0.02298	0.03881	0.02579	0.02654	0.02412	0.03454	0.01949	0.05227	0.03577	0.03725	0.04938	0.06691	0.04371
AcylPG 16:0-36:3	0.01466	0.01929	0.00848	0.01200	0.01050	0.01371	0.02540	0.01872	0.01947	0.01608	0.02277	0.01593	0.03989	0.02640	0.02830	0.03982	0.04781	0.03063
AcylPG 16:0-36:4	0.00429	0.00444	0.00260	0.00341	0.00225	0.00372	0.00284	0.00232	0.00218	0.00195	0.00164	0.00303	0.00485	0.00401	0.00308	0.00599	0.00592	0.00485
AcylPG 16:0-38:3	0.00241	0.00232	0.00202	0.00169	0.00175	0.00217	0.01619	0.01125	0.01217	0.01001	0.01565	0.00785	0.01800	0.01139	0.01452	0.01762	0.02405	0.01237
AcylPG 16:0-38:4	0.00235	0.00236	0.00188	0.00306	0.00169	0.00295	0.00158	0.00093	0.00102	0.00068	0.00114	0.00038	0.00198	0.00135	0.00200	0.00217	0.00186	0.00234
AcylPG 16:0-38:5	0.00468	0.00562	0.00431	0.00552	0.00360	0.00501	0.00143	0.00079	0.00162	0.00116	0.00196	0.00070	0.00297	0.00292	0.00177	0.00342	0.00450	0.00216
LPE 18:0	0.07822	0.06279	0.03480	0.07325	0.03841	0.04776	0.06122	0.04529	0.03294	0.05424	0.02091	0.03480	0.06185	0.01990	0.04047	0.04515	0.06145	0.01438
LPI 16:0	0.00504	0.00945	0.00142	0.00006	0.00325	0.00007	0.02739	0.00818	0.00729	0.01657	0.00831	0.00114	0.00214	0.00072	0.00366	0.00313	0.00442	0.00283
LPI 18:0	0.03551	0.03313	0.00152	0.00100	0.02046	0.00563	0.08083	0.02881	0.04405	0.02777	0.03711	0.00427	0.02101	0.02642	0.01719	0.00571	0.04074	0.00218
LPI 18:1	0.00634	0.00600	0.00143	0.00000	0.00057	0.00000	0.01867	0.00634	0.00720	0.00642	0.00738	0.00556	0.00268	0.00363	0.00333	0.00540	0.00253	0.00000
LPI 20:3	0.00198	-0.00006	0.00135	0.00000	0.00000	0.00122	0.01741	0.00780	0.00763	0.01198	0.00501	0.00000	0.00211	0.00547	0.00242	0.00108	0.00411	0.00076
LPI 20:4	0.00755	0.00278	0.00270	0.00205	0.00256	0.00390	0.00821	0.00198	0.00116	0.00462	0.00283	0.00319	0.00034	0.00257	0.00581	0.00299	0.00622	0.00194
LPS 16:0	0.02744	0.02695	0.00205	0.00261	0.01558	0.01557	0.02612	0.01361	0.02434	0.01846	0.04658	0.00000	0.01679	0.01604	0.03156	0.02813	0.05919	0.02024
LPS 18:0	0.22532	0.14979	0.10611	0.08125	0.21849	0.08674	0.19727	0.10654	0.14842	0.24229	0.29908	0.04733	0.08807	0.13623	0.09007	0.15424	0.34395	0.10707
LPS 18:1	0.01730	0.02343	0.01779	0.02167	0.04202	0.02027	0.07551	0.04887	0.03517	0.03166	0.06252	0.00822	0.02004	0.02561	0.02935	0.03606	0.08089	0.03982
LPS 20:4	0.01595	0.02773	0.00856	0.00365	0.01568	0.00437	0.00748	0.01412	0.00255	0.01481	0.00210	0.00408	0.00582	0.00891	0.00669	0.01440	0.00779	0.01228
NAPE 16:0/18:0/20:4	0.00878	0.01292	0.00882	0.00838	0.00685	0.01062	0.00777	0.00608	0.00624	0.00468	0.00669	0.00410	0.01474	0.01015	0.00884	0.01402	0.01609	0.01196
NAPE 18:0/18:1/20:4	0.01507	0.01493	0.00803	0.01096	0.00766	0.01159	0.00801	0.00711	0.00612	0.00607	0.00928	0.00505	0.01831	0.01221	0.01207	0.01997	0.02018	0.01372
NAPE 18:0/20:4/20:4	0.00763	0.00663	0.00401	0.00552	0.00330	0.00586	0.00183	0.00141	0.00117	0.00103	0.00208	0.00064	0.00282	0.00178	0.00206	0.00350	0.00448	0.00274
NAPE 18:1/18:1/20:4	0.01796	0.01554	0.01027	0.01459	0.00852	0.01653	0.00718	0.00449	0.00418	0.00412	0.00706	0.00436	0.01611	0.00873	0.00891	0.01569	0.01690	0.01143
NAPE p16:0/18:0/20:4	0.00306	0.00241	0.00164	0.00204	0.00138	0.00188	0.00271	0.00162	0.00202	0.00175	0.00223	0.00138	0.00355	0.00320	0.00300	0.00345	0.00361	0.00330
NAPE p18:0/18:1/20:4	0.00314	0.00414	0.00258	0.00259	0.00193	0.00313	0.00329	0.00282	0.00243	0.00219	0.00290	0.00239	0.00613	0.00435	0.00336	0.00486	0.00608	0.00435
NAPE p18:0/20:4/20:4	0.00494	0.00447	0.00307	0.00474	0.00369	0.00482	0.00198	0.00125	0.00141	0.00160	0.00171	0.00097	0.00243	0.00177	0.00243	0.00220	0.00449	0.00269
NAPE p18:0/22:4/20:4	0.00358	0.00380	0.00115	0.00294	0.00186	0.00353	0.00072	0.00055	0.00047	0.00039	0.00052	0.00048	0.00105	0.00062	0.00032	0.00139	0.00079	0.00065
NAPE p18:0/22:6/20:4	0.00085	0.00112	0.00081	0.00126	0.00079	0.00089	0.00069	0.00042	0.00039	0.00032	0.00011	0.00024	0.00143	0.00057	0.00038	0.00131	0.00147	0.00059
NAPE p18:1/18:1/20:4	0.01161	0.01228	0.00784	0.00954	0.00672	0.00902	0.01557	0.01212	0.01066	0.01061	0.01525	0.00926	0.02279	0.01563	0.01725	0.02386	0.02554	0.01881
NAPE p18:1/20:4/20:4	0.01745	0.02079	0.01182	0.01397	0.01078	0.01466	0.00770	0.00651	0.00436	0.00571	0.00659	0.00538	0.01385	0.00957	0.00801	0.01515	0.01695	0.01134
NSer 16:0	0.04287	0.01506	0.01971	0.03219	0.02274	0.01600	0.01440	0.00506	0.00758	0.00143	0.03958	0.00813	0.35996	0.09064	0.05129	0.07239	0.06595	0.04759
MS_METABOLITE_DATA_END
#METABOLITES
METABOLITES_START
metabolite_name
Sulf d18:0/16:1
Sulf d18:0/18:1
Sulf d18:0/22:1
Sulf d18:0/24:1
Sulf d18:1/16:0
Sulf d18:1/18:0
Sulf d18:1/22:0
Sulf d18:1/24:0
Sulf d18:1/24:1
GM3 d18:0/16:1
GM3 d18:0/18:1
GM3 d18:0/20:1
PA 30:0
PA 32:0
PA 32:1
PA 34:0
PA 34:1
PA 36:1
PA 38:3
PA 38:4
PA 40:6
PE 32:0
PE 32:1
PE 34:0
PE 34:1
PE 34:2
PE 36:0
PE 36:1
PE 36:2
PE 36:3
PE 36:4
PE 38:0
PE 38:1
PE 38:2
PE 38:3
PE 38:4
PE 38:5
PE 38:6
PE 40:4
PE 40:5
PE 40:6
PE 40:7
PEp 32:0
PEp 32:1
PEp 34:0
PEp 34:1
PEp 34:2
PEp 36:0
PEp 36:1
PEp 36:2
PEp 36:3
PEp 36:4
PEp 38:0
PEp 38:3
PEp 38:4
PEp 38:5
PEp 38:6
PEp 40:4
PEp 40:5
PEp 40:6
PEp 40:7
PS 32:0
PS 32:1
PS 34:0
PS 34:1
PS 34:2
PS 36:0
PS 36:1
PS 36:2
PS 36:3
PS 36:4
PS 38:1
PS 38:2
PS 38:3
PS 38:4
PS 38:5
PS 38:6
PS 40:4
PS 40:5
PS 40:6
PS 40:7
PS 42:5
PS 42:6
PS 42:7
PI 32:1
PI 34:1
PI 34:2
PI 36:1
PI 36:2
PI 36:3
PI 36:4
PI 38:2
PI 38:3
PI 38:4
PI 38:5
PI 38:6
PI 40:4
PI 40:5
PI 40:6
PI 40:7
PG 30:0
PG 32:1
PG 34:0
PG 34:1
PG 34:2
PG 36:1
PG 36:2
PG 36:3
PG 36:4
PG 38:4
BMP 32:1
BMP 34:1
BMP 36:1
BMP 36:2
BMP 38:2
BMP 38:3
BMP 40:7
AcylPG 16:0-34:0
AcylPG 16:0-34:1
AcylPG 16:0-34:2
AcylPG 16:0-36:0
AcylPG 16:0-36:1
AcylPG 16:0-36:2
AcylPG 16:0-36:3
AcylPG 16:0-36:4
AcylPG 16:0-38:3
AcylPG 16:0-38:4
AcylPG 16:0-38:5
LPE 18:0
LPI 16:0
LPI 18:0
LPI 18:1
LPI 20:3
LPI 20:4
LPS 16:0
LPS 18:0
LPS 18:1
LPS 20:4
NAPE 16:0/18:0/20:4
NAPE 18:0/18:1/20:4
NAPE 18:0/20:4/20:4
NAPE 18:1/18:1/20:4
NAPE p16:0/18:0/20:4
NAPE p18:0/18:1/20:4
NAPE p18:0/20:4/20:4
NAPE p18:0/22:4/20:4
NAPE p18:0/22:6/20:4
NAPE p18:1/18:1/20:4
NAPE p18:1/20:4/20:4
NSer 16:0
METABOLITES_END
#END