#METABOLOMICS WORKBENCH alhughes3_20210722_081823 DATATRACK_ID:2764 STUDY_ID:ST001901 ANALYSIS_ID:AN003092
VERSION                          	1
CREATED_ON                       	02-08-2024
#PROJECT
PR:PROJECT_TITLE                 	Mitochondrial-Derived Compartments Facilitate Cellular Adaptation to Amino Acid
PR:PROJECT_TITLE                 	Stress
PR:PROJECT_SUMMARY               	Amino acids are essential building blocks of life. However, increasing evidence
PR:PROJECT_SUMMARY               	suggests that elevated amino acids cause cellular toxicity associated with
PR:PROJECT_SUMMARY               	numerous metabolic disorders. How cells cope with elevated amino acids remains
PR:PROJECT_SUMMARY               	poorly understood. Here, we show that a previously identified cellular
PR:PROJECT_SUMMARY               	structure, the mitochondrial-derived compartment (MDC), functions to protect
PR:PROJECT_SUMMARY               	cells from amino acid stress. In response to amino acid elevation, MDCs are
PR:PROJECT_SUMMARY               	generated from mitochondria, where they selectively sequester and deplete SLC25A
PR:PROJECT_SUMMARY               	nutrient carriers and their associated import receptor Tom70 from the organelle.
PR:PROJECT_SUMMARY               	Generation of MDCs promotes amino acid catabolism, and their formation occurs
PR:PROJECT_SUMMARY               	simultaneously with transporter removal at the plasma membrane via the
PR:PROJECT_SUMMARY               	multi-vesicular body (MVB) pathway. Combined loss of vacuolar amino acid
PR:PROJECT_SUMMARY               	storage, MVBs and MDCs renders cells sensitive to high amino acid stress. Thus,
PR:PROJECT_SUMMARY               	we propose that MDCs operate as part of a coordinated cell network that
PR:PROJECT_SUMMARY               	facilitates amino acid homoeostasis through post-translational nutrient
PR:PROJECT_SUMMARY               	transporter remodeling.
PR:INSTITUTE                     	University of Utah School of Medicine
PR:DEPARTMENT                    	Biochemistry
PR:LABORATORY                    	Hughes Lab
PR:LAST_NAME                     	Hughes
PR:FIRST_NAME                    	Adam
PR:ADDRESS                       	15 N Medical Drive East, RM 4100, Salt Lake City, UT, 84112, USA
PR:EMAIL                         	hughes@biochem.utah.edu
PR:PHONE                         	8015812481
PR:DOI                           	http://dx.doi.org/10.21228/M83X4N
#STUDY
ST:STUDY_TITLE                   	Mitochondrial-Derived Compartments Facilitate Cellular Adaptation to Amino Acid
ST:STUDY_TITLE                   	Stress
ST:STUDY_SUMMARY                 	Amino acids are essential building blocks of life. However, increasing evidence
ST:STUDY_SUMMARY                 	suggests that elevated amino acids cause cellular toxicity associated with
ST:STUDY_SUMMARY                 	numerous metabolic disorders. How cells cope with elevated amino acids remains
ST:STUDY_SUMMARY                 	poorly understood. Here, we show that a previously identified cellular
ST:STUDY_SUMMARY                 	structure, the mitochondrial-derived compartment (MDC), functions to protect
ST:STUDY_SUMMARY                 	cells from amino acid stress. In response to amino acid elevation, MDCs are
ST:STUDY_SUMMARY                 	generated from mitochondria, where they selectively sequester and deplete SLC25A
ST:STUDY_SUMMARY                 	nutrient carriers and their associated import receptor Tom70 from the organelle.
ST:STUDY_SUMMARY                 	Generation of MDCs promotes amino acid catabolism, and their formation occurs
ST:STUDY_SUMMARY                 	simultaneously with transporter removal at the plasma membrane via the
ST:STUDY_SUMMARY                 	multi-vesicular body (MVB) pathway. Combined loss of vacuolar amino acid
ST:STUDY_SUMMARY                 	storage, MVBs and MDCs renders cells sensitive to high amino acid stress. Thus,
ST:STUDY_SUMMARY                 	we propose that MDCs operate as part of a coordinated cell network that
ST:STUDY_SUMMARY                 	facilitates amino acid homoeostasis through post-translational nutrient
ST:STUDY_SUMMARY                 	transporter remodeling.
ST:INSTITUTE                     	University of Utah School of Medicine
ST:DEPARTMENT                    	Biochemistry
ST:LABORATORY                    	Hughes Lab
ST:LAST_NAME                     	Hughes
ST:FIRST_NAME                    	Adam
ST:ADDRESS                       	15 N Medical Drive East, RM 4100, Salt Lake City, UT, 84112, USA
ST:EMAIL                         	hughes@biochem.utah.edu
ST:PHONE                         	8015812481
ST:SUBMIT_DATE                   	2021-07-22
#SUBJECT
SU:SUBJECT_TYPE                  	Yeast
SU:SUBJECT_SPECIES               	Saccharomyces cerevisiae
SU:TAXONOMY_ID                   	4932
#SUBJECT_SAMPLE_FACTORS:         	SUBJECT(optional)[tab]SAMPLE[tab]FACTORS(NAME:VALUE pairs separated by |)[tab]Additional sample data
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200818_7200_20to1_Yeast_6A	Genotype:gem1 knockout | Media:SD+Leucine | Treatment:ConcA	RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_6A.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200818_7200_20to1_Yeast_6B	Genotype:gem1 knockout | Media:SD+Leucine | Treatment:ConcA	RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_6B.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200818_7200_20to1_Yeast_6C	Genotype:gem1 knockout | Media:SD+Leucine | Treatment:ConcA	RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_6C.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200818_7200_20to1_Yeast_6D	Genotype:gem1 knockout | Media:SD+Leucine | Treatment:ConcA	RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_6D.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200818_7200_20to1_Yeast_2A	Genotype:gem1 knockout | Media:SD+Leucine | Treatment:DMSO	RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_2A.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200818_7200_20to1_Yeast_2B	Genotype:gem1 knockout | Media:SD+Leucine | Treatment:DMSO	RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_2B.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200818_7200_20to1_Yeast_2C	Genotype:gem1 knockout | Media:SD+Leucine | Treatment:DMSO	RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_2C.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200818_7200_20to1_Yeast_2D	Genotype:gem1 knockout | Media:SD+Leucine | Treatment:DMSO	RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_2D.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_11	Genotype:gem1 knockout | Media:YPAD | Treatment:ConcA	RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_11.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_17	Genotype:gem1 knockout | Media:YPAD | Treatment:ConcA	RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_17.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_23	Genotype:gem1 knockout | Media:YPAD | Treatment:ConcA	RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_23.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_5a	Genotype:gem1 knockout | Media:YPAD | Treatment:ConcA	RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_5a.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200825_7200_20to1_MSTFA_11	Genotype:gem1 knockout | Media:YPAD | Treatment:ConcA	RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_11.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200825_7200_20to1_MSTFA_17	Genotype:gem1 knockout | Media:YPAD | Treatment:ConcA	RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_17.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200825_7200_20to1_MSTFA_23	Genotype:gem1 knockout | Media:YPAD | Treatment:ConcA	RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_23.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200825_7200_20to1_MSTFA_5	Genotype:gem1 knockout | Media:YPAD | Treatment:ConcA	RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_5.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_10	Genotype:gem1 knockout | Media:YPAD | Treatment:DMSO	RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_10.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_16	Genotype:gem1 knockout | Media:YPAD | Treatment:DMSO	RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_16.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_22	Genotype:gem1 knockout | Media:YPAD | Treatment:DMSO	RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_22.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_4	Genotype:gem1 knockout | Media:YPAD | Treatment:DMSO	RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_4.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200825_7200_20to1_MSTFA_10	Genotype:gem1 knockout | Media:YPAD | Treatment:DMSO	RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_10.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200825_7200_20to1_MSTFA_16	Genotype:gem1 knockout | Media:YPAD | Treatment:DMSO	RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_16.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200825_7200_20to1_MSTFA_22	Genotype:gem1 knockout | Media:YPAD | Treatment:DMSO	RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_22.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200825_7200_20to1_MSTFA_4	Genotype:gem1 knockout | Media:YPAD | Treatment:DMSO	RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_4.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_12	Genotype:gem1 knockout | Media:YPAD | Treatment:Rap	RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_12.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_18	Genotype:gem1 knockout | Media:YPAD | Treatment:Rap	RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_18.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_24	Genotype:gem1 knockout | Media:YPAD | Treatment:Rap	RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_24.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_5	Genotype:gem1 knockout | Media:YPAD | Treatment:Rap	RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_5.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200825_7200_20to1_MSTFA_12	Genotype:gem1 knockout | Media:YPAD | Treatment:Rap	RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_12.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200825_7200_20to1_MSTFA_18	Genotype:gem1 knockout | Media:YPAD | Treatment:Rap	RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_18.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200825_7200_20to1_MSTFA_24	Genotype:gem1 knockout | Media:YPAD | Treatment:Rap	RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_24.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200825_7200_20to1_MSTFA_6	Genotype:gem1 knockout | Media:YPAD | Treatment:Rap	RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_6.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200818_7200_20to1_Yeast_4D	Genotype:gem1 vps27 double knockout | Media:SD+Leucine | Treatment:ConcA	RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_4D.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200818_7200_20to1_Yeast_8A	Genotype:gem1 vps27 double knockout | Media:SD+Leucine | Treatment:ConcA	RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_8A.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200818_7200_20to1_Yeast_8B	Genotype:gem1 vps27 double knockout | Media:SD+Leucine | Treatment:ConcA	RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_8B.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200818_7200_20to1_Yeast_8C	Genotype:gem1 vps27 double knockout | Media:SD+Leucine | Treatment:ConcA	RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_8C.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200818_7200_20to1_Yeast_8D	Genotype:gem1 vps27 double knockout | Media:SD+Leucine | Treatment:ConcA	RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_8D.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200818_7200_20to1_Yeast_4A	Genotype:gem1 vps27 double knockout | Media:SD+Leucine | Treatment:DMSO	RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_4A.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200818_7200_20to1_Yeast_4B	Genotype:gem1 vps27 double knockout | Media:SD+Leucine | Treatment:DMSO	RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_4B.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200818_7200_20to1_Yeast_4C	Genotype:gem1 vps27 double knockout | Media:SD+Leucine | Treatment:DMSO	RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_4C.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20190522_5977b_10to1_Yeast_QC5	Genotype:Pooled QC sample | Media:N/A | Treatment:N/A	RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_QC5.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20190522_5977b_10to1_Yeast_QC6	Genotype:Pooled QC sample | Media:N/A | Treatment:N/A	RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_QC6.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20190522_5977b_10to1_Yeast_QC7	Genotype:Pooled QC sample | Media:N/A | Treatment:N/A	RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_QC7.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20190522_5977b_10to1_Yeast_QC8	Genotype:Pooled QC sample | Media:N/A | Treatment:N/A	RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_QC8.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_QC1	Genotype:Pooled QC sample | Media:N/A | Treatment:N/A	RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_QC1.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_QC2	Genotype:Pooled QC sample | Media:N/A | Treatment:N/A	RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_QC2.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_QC3	Genotype:Pooled QC sample | Media:N/A | Treatment:N/A	RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_QC3.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_QC4	Genotype:Pooled QC sample | Media:N/A | Treatment:N/A	RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_QC4.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200818_7200_20to1_Yeast_QC1	Genotype:Pooled QC sample | Media:N/A | Treatment:N/A	RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_QC1.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200818_7200_20to1_Yeast_QC2	Genotype:Pooled QC sample | Media:N/A | Treatment:N/A	RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_QC2.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200818_7200_20to1_Yeast_QC3	Genotype:Pooled QC sample | Media:N/A | Treatment:N/A	RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_QC3.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200818_7200_20to1_Yeast_QC4	Genotype:Pooled QC sample | Media:N/A | Treatment:N/A	RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_QC4.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200825_7200_20to1_MSTFA_QC1	Genotype:Pooled QC sample | Media:N/A | Treatment:N/A	RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_QC1.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200825_7200_20to1_MSTFA_QC2	Genotype:Pooled QC sample | Media:N/A | Treatment:N/A	RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_QC2.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200825_7200_20to1_MSTFA_QC3	Genotype:Pooled QC sample | Media:N/A | Treatment:N/A	RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_QC3.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200825_7200_20to1_MSTFA_QC4	Genotype:Pooled QC sample | Media:N/A | Treatment:N/A	RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_QC4.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20190522_5977b_10to1_Yeast_PB4	Genotype:Process blank | Media:N/A | Treatment:N/A	RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_PB4.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20190522_5977b_10to1_Yeast_PB5	Genotype:Process blank | Media:N/A | Treatment:N/A	RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_PB5.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20190522_5977b_10to1_Yeast_PB6	Genotype:Process blank | Media:N/A | Treatment:N/A	RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_PB6.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_PB1	Genotype:Process blank | Media:N/A | Treatment:N/A	RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_PB1.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_PB2	Genotype:Process blank | Media:N/A | Treatment:N/A	RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_PB2.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_PB3	Genotype:Process blank | Media:N/A | Treatment:N/A	RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_PB3.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_PB4	Genotype:Process blank | Media:N/A | Treatment:N/A	RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_PB4.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200818_7200_20to1_Yeast_PB1	Genotype:Process blank | Media:N/A | Treatment:N/A	RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_PB1.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200818_7200_20to1_Yeast_PB2	Genotype:Process blank | Media:N/A | Treatment:N/A	RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_PB2.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200818_7200_20to1_Yeast_PB3	Genotype:Process blank | Media:N/A | Treatment:N/A	RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_PB3.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200818_7200_20to1_Yeast_PB4	Genotype:Process blank | Media:N/A | Treatment:N/A	RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_PB4.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200825_7200_20to1_MSTFA_PB1	Genotype:Process blank | Media:N/A | Treatment:N/A	RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_PB1.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200825_7200_20to1_MSTFA_PB2	Genotype:Process blank | Media:N/A | Treatment:N/A	RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_PB2.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200825_7200_20to1_MSTFA_PB3	Genotype:Process blank | Media:N/A | Treatment:N/A	RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_PB3.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200825_7200_20to1_MSTFA_PB4	Genotype:Process blank | Media:N/A | Treatment:N/A	RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_PB4.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200818_7200_20to1_Yeast_7A	Genotype:vps27 knockout | Media:SD+Leucine | Treatment:ConcA	RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_7A.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200818_7200_20to1_Yeast_7B	Genotype:vps27 knockout | Media:SD+Leucine | Treatment:ConcA	RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_7B.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200818_7200_20to1_Yeast_7C	Genotype:vps27 knockout | Media:SD+Leucine | Treatment:ConcA	RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_7C.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200818_7200_20to1_Yeast_7D	Genotype:vps27 knockout | Media:SD+Leucine | Treatment:ConcA	RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_7D.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200818_7200_20to1_Yeast_3A	Genotype:vps27 knockout | Media:SD+Leucine | Treatment:DMSO	RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_3A.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200818_7200_20to1_Yeast_3B	Genotype:vps27 knockout | Media:SD+Leucine | Treatment:DMSO	RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_3B.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200818_7200_20to1_Yeast_3C	Genotype:vps27 knockout | Media:SD+Leucine | Treatment:DMSO	RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_3C.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200818_7200_20to1_Yeast_3D	Genotype:vps27 knockout | Media:SD+Leucine | Treatment:DMSO	RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_3D.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20190522_5977b_10to1_Yeast_34	Genotype:wild-type | Media:MinD | Treatment:DMSO	RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_34.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20190522_5977b_10to1_Yeast_43	Genotype:wild-type | Media:MinD | Treatment:DMSO	RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_43.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20190522_5977b_10to1_Yeast_52	Genotype:wild-type | Media:MinD | Treatment:DMSO	RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_52.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200818_7200_20to1_Yeast_5A	Genotype:wild-type | Media:SD+Leucine | Treatment:ConcA	RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_5A.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200818_7200_20to1_Yeast_5B	Genotype:wild-type | Media:SD+Leucine | Treatment:ConcA	RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_5B.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200818_7200_20to1_Yeast_5C	Genotype:wild-type | Media:SD+Leucine | Treatment:ConcA	RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_5C.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200818_7200_20to1_Yeast_5D	Genotype:wild-type | Media:SD+Leucine | Treatment:ConcA	RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_5D.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200818_7200_20to1_Yeast_1A	Genotype:wild-type | Media:SD+Leucine | Treatment:DMSO	RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_1A.D; Experiment identifier=MDCY-205; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=S7G
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200818_7200_20to1_Yeast_1B	Genotype:wild-type | Media:SD+Leucine | Treatment:DMSO	RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_1B.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200818_7200_20to1_Yeast_1C	Genotype:wild-type | Media:SD+Leucine | Treatment:DMSO	RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_1C.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200818_7200_20to1_Yeast_1D	Genotype:wild-type | Media:SD+Leucine | Treatment:DMSO	RAW_FILE_NAME=Hughes_Schuler_20200818_7200_20to1_Yeast_1D.D; Experiment identifier=MDCY-205; Submission date=08.18.20; Analysis=Whole cell mtabolites; Figures=S7G
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20190522_5977b_10to1_Yeast_31	Genotype:wild-type | Media:SD | Treatment:DMSO	RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_31.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20190522_5977b_10to1_Yeast_40	Genotype:wild-type | Media:SD | Treatment:DMSO	RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_40.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20190522_5977b_10to1_Yeast_49	Genotype:wild-type | Media:SD | Treatment:DMSO	RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_49.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_14	Genotype:wild-type | Media:YPAD | Treatment:ConcA	RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_14.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_2	Genotype:wild-type | Media:YPAD | Treatment:ConcA	RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_2.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_20	Genotype:wild-type | Media:YPAD | Treatment:ConcA	RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_20.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_8	Genotype:wild-type | Media:YPAD | Treatment:ConcA	RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_8.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200825_7200_20to1_MSTFA_14	Genotype:wild-type | Media:YPAD | Treatment:ConcA	RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_14.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200825_7200_20to1_MSTFA_2	Genotype:wild-type | Media:YPAD | Treatment:ConcA	RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_2.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200825_7200_20to1_MSTFA_20	Genotype:wild-type | Media:YPAD | Treatment:ConcA	RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_20.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200825_7200_20to1_MSTFA_8	Genotype:wild-type | Media:YPAD | Treatment:ConcA	RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_8.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20190522_5977b_10to1_Yeast_28	Genotype:wild-type | Media:YPAD | Treatment:DMSO	RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_28.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20190522_5977b_10to1_Yeast_37	Genotype:wild-type | Media:YPAD | Treatment:DMSO	RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_37.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20190522_5977b_10to1_Yeast_46	Genotype:wild-type | Media:YPAD | Treatment:DMSO	RAW_FILE_NAME=Hughes_Schuler_20190522_5977b_10to1_Yeast_46.cdf; Experiment identifier=MDCY-80; Submission date=05.17.19; Analysis=Whole cell mtabolites; Figures=S3
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_1	Genotype:wild-type | Media:YPAD | Treatment:DMSO	RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_1.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_13	Genotype:wild-type | Media:YPAD | Treatment:DMSO	RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_13.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_19	Genotype:wild-type | Media:YPAD | Treatment:DMSO	RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_19.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_7	Genotype:wild-type | Media:YPAD | Treatment:DMSO	RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_7.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200825_7200_20to1_MSTFA_1	Genotype:wild-type | Media:YPAD | Treatment:DMSO	RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_1.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200825_7200_20to1_MSTFA_13	Genotype:wild-type | Media:YPAD | Treatment:DMSO	RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_13.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200825_7200_20to1_MSTFA_19	Genotype:wild-type | Media:YPAD | Treatment:DMSO	RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_19.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200825_7200_20to1_MSTFA_7	Genotype:wild-type | Media:YPAD | Treatment:DMSO	RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_7.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_15	Genotype:wild-type | Media:YPAD | Treatment:Rap	RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_15.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_21	Genotype:wild-type | Media:YPAD | Treatment:Rap	RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_21.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_3	Genotype:wild-type | Media:YPAD | Treatment:Rap	RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_3.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_9	Genotype:wild-type | Media:YPAD | Treatment:Rap	RAW_FILE_NAME=Hughes_Schuler_20200807_MSTFA_5977b_20to1_SC_9.cdf; Experiment identifier=MDCY-202; Submission date=7/8/20; Analysis=Whole cell mtabolites; Figures=2A, 2C, S2A, S3G, 6A, 6B, S6A
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200825_7200_20to1_MSTFA_15	Genotype:wild-type | Media:YPAD | Treatment:Rap	RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_15.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200825_7200_20to1_MSTFA_21	Genotype:wild-type | Media:YPAD | Treatment:Rap	RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_21.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200825_7200_20to1_MSTFA_3	Genotype:wild-type | Media:YPAD | Treatment:Rap	RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_3.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E
SUBJECT_SAMPLE_FACTORS           	-	Hughes_Schuler_20200825_7200_20to1_MSTFA_9	Genotype:wild-type | Media:YPAD | Treatment:Rap	RAW_FILE_NAME=Hughes_Schuler_20200825_7200_20to1_MSTFA_9.D; Experiment identifier=MDCY-211; Submission date=08.25.20; Analysis=13C6-Glucosetracing; Figures=2D, 2E, S2B, S2C, S2D, S3H, 6B, 6C, 6D, S6B, S6C, S6D, S6E
#COLLECTION
CO:COLLECTION_SUMMARY            	See STAR methods file
CO:COLLECTION_PROTOCOL_FILENAME  	STAR_methods.pdf
CO:SAMPLE_TYPE                   	Yeast cells
#TREATMENT
TR:TREATMENT_SUMMARY             	See STAR Methods file
TR:TREATMENT_PROTOCOL_FILENAME   	STAR_methods.pdf
#SAMPLEPREP
SP:SAMPLEPREP_SUMMARY            	See STAR Methods file
SP:SAMPLEPREP_PROTOCOL_FILENAME  	STAR_methods.pdf
#CHROMATOGRAPHY
CH:INSTRUMENT_NAME               	Agilent 5977B
CH:COLUMN_NAME                   	Phenomenex Zebron ZB-WAXplus (30m x 0.25mm,0.25um)
CH:CHROMATOGRAPHY_TYPE           	GC
#ANALYSIS
AN:ANALYSIS_TYPE                 	MS
#MS
MS:INSTRUMENT_NAME               	Agilent 5977B
MS:INSTRUMENT_TYPE               	Single quadrupole
MS:MS_TYPE                       	EI
MS:MS_COMMENTS                   	N/A
MS:ION_MODE                      	POSITIVE
#MS_METABOLITE_DATA
MS_METABOLITE_DATA:UNITS         	area under the curve
MS_METABOLITE_DATA_START
Samples	Hughes_Schuler_20190522_5977b_10to1_Yeast_QC5	Hughes_Schuler_20190522_5977b_10to1_Yeast_QC6	Hughes_Schuler_20190522_5977b_10to1_Yeast_QC7	Hughes_Schuler_20190522_5977b_10to1_Yeast_QC8	Hughes_Schuler_20190522_5977b_10to1_Yeast_PB4	Hughes_Schuler_20190522_5977b_10to1_Yeast_PB5	Hughes_Schuler_20190522_5977b_10to1_Yeast_PB6	Hughes_Schuler_20190522_5977b_10to1_Yeast_34	Hughes_Schuler_20190522_5977b_10to1_Yeast_43	Hughes_Schuler_20190522_5977b_10to1_Yeast_52	Hughes_Schuler_20190522_5977b_10to1_Yeast_31	Hughes_Schuler_20190522_5977b_10to1_Yeast_40	Hughes_Schuler_20190522_5977b_10to1_Yeast_49	Hughes_Schuler_20190522_5977b_10to1_Yeast_28	Hughes_Schuler_20190522_5977b_10to1_Yeast_37	Hughes_Schuler_20190522_5977b_10to1_Yeast_46
Factors	Genotype:Pooled QC sample | Media:N/A | Treatment:N/A	Genotype:Pooled QC sample | Media:N/A | Treatment:N/A	Genotype:Pooled QC sample | Media:N/A | Treatment:N/A	Genotype:Pooled QC sample | Media:N/A | Treatment:N/A	Genotype:Process blank | Media:N/A | Treatment:N/A	Genotype:Process blank | Media:N/A | Treatment:N/A	Genotype:Process blank | Media:N/A | Treatment:N/A	Genotype:wild-type | Media:MinD | Treatment:DMSO	Genotype:wild-type | Media:MinD | Treatment:DMSO	Genotype:wild-type | Media:MinD | Treatment:DMSO	Genotype:wild-type | Media:SD | Treatment:DMSO	Genotype:wild-type | Media:SD | Treatment:DMSO	Genotype:wild-type | Media:SD | Treatment:DMSO	Genotype:wild-type | Media:YPAD | Treatment:DMSO	Genotype:wild-type | Media:YPAD | Treatment:DMSO	Genotype:wild-type | Media:YPAD | Treatment:DMSO	
1_6-anhydro-glucose	6332.0000	8739.0000	8575.0000	13142.0000	775.0000	491.0000		6397.0000	7488.0000	8177.0000	6265.0000	2599.0000	5217.0000	7579.0000	10189.0000	8802.0000
1-monomyristin	1226.0000		817.0000		781.0000		714.0000	1115.0000	1268.0000			608.0000	601.0000	1869.0000	2713.0000	5728.0000
1-octadecene	3058.0000	4541.0000	8924.0000	8988.0000	3475.0000			2812.0000	2772.0000	5257.0000	3951.0000		5078.0000	4213.0000	6430.0000	5558.0000
1-Palmitoylglycerol	1374.0000	101.0000	2486.0000	3904.0000	1263.0000			2029.0000	1537.0000	5798.0000	2682.0000	3512.0000	2171.0000	286.0000	1921.0000	3043.0000
1-Steroylglycerol	16932.0000	17108.0000	20656.0000	36720.0000	11202.0000	13913.0000	23052.0000	19264.0000	15303.0000	18764.0000	16456.0000	13244.0000	17587.0000	17478.0000	22128.0000	16254.0000
2^3^-Bisphosphoglycerate		2934.0000					1435.0000				390.0000		641.0000	809.0000	292.0000	1364.0000
2-Hydroxybenzoic acid	1342.0000		860.0000	1556.0000			451.0000	537.0000	889.0000	1188.0000	565.0000			108.0000	923.0000	323.0000
2-Hydroxybutyric acid 2	58772.0000	66513.0000	63533.0000	67625.0000	65043.0000	51026.0000	27285.0000	59888.0000	45728.0000	55414.0000	52620.0000	50720.0000	56622.0000	66976.0000	84740.0000	53209.0000
2-Hydroxyglutaric acid 1	1903.0000	3485.0000	4616.0000	6799.0000	5067.0000			4807.0000	2635.0000	3692.0000	1457.0000	1637.0000	1530.0000	4538.0000	6247.0000	7256.0000
2-ketoglutarate		744.0000		620.0000	844.0000			130.0000	756.0000		1319.0000		1036.0000			673.0000
2-Ketoisocaproic acid		1454.0000	1382.0000	2109.0000	1535.0000	3450.0000	4551.0000			627.0000		1071.0000	1611.0000	657.0000	3904.0000	
2-monopalmitoylglycerol	1889.0000	2545.0000	2867.0000	8779.0000	1355.0000	1657.0000		2267.0000	2023.0000	3848.0000	1525.0000	4308.0000	2981.0000	2765.0000	3247.0000	4387.0000
2-Steroylglycerol		2647.0000		590.0000		189.0000	1135.0000									
3-hydroxybutyric acid	3774.0000	4597.0000	5327.0000	10675.0000	2481.0000	593.0000	4559.0000	4991.0000	3000.0000		1289.0000			9096.0000	21934.0000	10940.0000
3-Phosphoglyceric acid		917.0000	839.0000	866.0000			187.0000	377.0000	342.0000	89.0000	369.0000	165.0000	246.0000	876.0000	211.0000	174.0000
4-Hydroxyproline 1		2152.0000		3173.0000			3660.0000	13503.0000				2950.0000		11469.0000	3065.0000	
4-Hydroxyproline 2	3629.0000			2516.0000			4031.0000									3015.0000
5-hydroxytryptophan		1071.0000	1181.0000		122.0000	153.0000	415.0000		1281.0000	2200.0000	1444.0000	656.0000			841.0000	626.0000
Adenine	33347.0000	50027.0000	61167.0000	92806.0000	671.0000	854.0000	944.0000	53481.0000	37591.0000	33423.0000	28724.0000	24548.0000	25082.0000	29490.0000	47258.0000	43014.0000
Adenosine	16188.0000	11517.0000	15517.0000	31274.0000		993.0000	271.0000	13309.0000	21016.0000	20759.0000	6508.0000	8834.0000	8472.0000	38216.0000	62813.0000	51449.0000
Adenosine monophosphate	26696.0000	27931.0000	37672.0000	61085.0000			383.0000	46751.0000	29638.0000	32383.0000	31403.0000	31471.0000	43272.0000	52293.0000	66050.0000	61046.0000
Adipic acid	683.0000	1109.0000	1319.0000	579.0000	649.0000	897.0000	1149.0000		810.0000		621.0000	579.0000	690.0000	236.0000	396.0000	
Allantoin	1202.0000		261.0000		645.0000	933.0000	367.0000		2121.0000		116.0000	419.0000				
alpha-D-glucosamine 1-phosphate					926.0000							446.0000				2729.0000
Aminoadipic acid	3762.0000	4728.0000	5795.0000	8038.0000	229.0000	167.0000		39939.0000	31469.0000	27729.0000	1790.0000	1328.0000	3099.0000	3626.0000	4297.0000	2971.0000
Arachidic acid	468.0000	593.0000		727.0000			65.0000								172.0000	956.0000
Arachidonic Acid	1822.0000	906.0000	2074.0000	6234.0000	202.0000	567.0000	284.0000	2054.0000	1296.0000			1857.0000	540.0000		1331.0000	
azelaic acid	8231.0000	7250.0000	10704.0000	9990.0000	2979.0000	1737.0000	2305.0000	10117.0000	5664.0000	9371.0000	4604.0000	4467.0000	7293.0000	7389.0000	11140.0000	11752.0000
Benzoic acid					1305.0000							547.0000	137.0000	416.0000		
Benzoquinone	970.0000		196.0000	2295.0000							1101.0000				3040.0000	3592.0000
Beta-Alanine	29227.0000	44509.0000	51899.0000	67482.0000	168.0000	381.0000	552.0000	187380.0000	160607.0000	138929.0000	670.0000		621.0000	1248.0000	2380.0000	941.0000
Beta-Glycerophosphoric acid	156.0000	125.0000	224.0000			196.0000			195.0000				219.0000	146.0000	105.0000	155.0000
Beta-lactate	18009.0000	28548.0000	37214.0000	41708.0000	21993.0000	16884.0000	21805.0000	29644.0000	26715.0000	22917.0000	24147.0000	16459.0000	21672.0000	43613.0000	54158.0000	55515.0000
Beta-Sitosterol				988.0000	1582.0000								2384.0000	2880.0000	2717.0000	
Capric acid	13400.0000	13803.0000	16430.0000	20514.0000	8903.0000	10019.0000	18386.0000	12871.0000	16592.0000	7172.0000	7184.0000	17364.0000	11531.0000	18964.0000	45915.0000	15383.0000
Cellobiose		763.0000			658.0000		352.0000		89.0000		499.0000			4191.0000	5122.0000	10681.0000
Cholesterol	77176.0000	65053.0000	54598.0000	176511.0000	910.0000			49107.0000	59828.0000	65518.0000	83174.0000	60835.0000	62974.0000	62926.0000	158469.0000	51568.0000
cis-Aconitic acid		866.0000		392.0000	322.0000			1018.0000							211.0000	
Citric acid	111869.0000	163842.0000	208721.0000	281446.0000	373.0000	375.0000		24372.0000	14228.0000	11130.0000	17386.0000	10404.0000	13733.0000	103584.0000	164537.0000	104524.0000
Creatinine	4976.0000	6246.0000	7884.0000	21320.0000			6078.0000	7654.0000	8070.0000	4551.0000	5678.0000	5799.0000	4135.0000	6971.0000	32687.0000	11811.0000
Cystathionine		3470.0000	5144.0000	15354.0000	678.0000	459.0000		490.0000	3297.0000	4720.0000		2774.0000	3341.0000	2291.0000	4885.0000	4849.0000
d4-succinate	5136.0000	12429.0000	6508.0000	3530.0000	4899.0000	13044.0000	7431.0000	16410.0000	12135.0000	15291.0000	4617.0000	4104.0000	5849.0000	3153.0000	9068.0000	4302.0000
Dehydroascorbic acid	4438.0000	5883.0000	7182.0000	8412.0000	351.0000			3386.0000	3136.0000		2775.0000	874.0000		3279.0000	2702.0000	
delta Amino Levulinic acid	14806.0000	16628.0000	24780.0000	21073.0000	1594.0000	1661.0000	2220.0000	5463.0000	6856.0000		16528.0000	10826.0000	13033.0000	11593.0000	26191.0000	24214.0000
D-Fructose 1	10083.0000	7194.0000	3214.0000	7259.0000	273.0000			2723.0000	1145.0000	4500.0000	3391.0000	7005.0000	7100.0000	8417.0000	13374.0000	2582.0000
D-Fructose 2	5865.0000	2633.0000	8533.0000	7599.0000	213.0000	180.0000		29550.0000	5391.0000	17294.0000	6005.0000	4245.0000	9703.0000	5170.0000	9606.0000	2966.0000
D-Galactose	1656516.0000	1692248.0000	2376936.0000	3234528.0000	972.0000	1031.0000	2354.0000	2143535.0000	1415752.0000	10924720.0000	2436460.0000	1459626.0000	1517264.0000	835052.0000	1390769.0000	4259928.0000
D-glucose 1	360446.0000	496729.0000	594546.0000	858957.0000	579.0000		1534.0000	2129258.0000	1403617.0000	10439440.0000	163653.0000	120535.0000	184985.0000	541251.0000	625085.0000	489317.0000
D-glucose 2	291806.0000	299555.0000	405071.0000	538136.0000	149.0000			321400.0000	215080.0000	1396452.0000	386533.0000	250322.0000	251629.0000	159783.0000	253610.0000	645515.0000
DHAP	67.0000	122.0000	320.0000		144.0000	221.0000		356.0000	274.0000	635.0000	201.0000	187.0000		112.0000	249.0000	343.0000
Diethyl Phthalate			5669.0000				3176.0000	6166.0000	6521.0000				2375.0000	12626.0000	23954.0000	
Diglycerol		186.0000	199.0000			119.0000					135.0000					225.0000
DL-3-Aminoisobutyric acid	537.0000	745.0000	953.0000	500.0000	224.0000	192.0000	327.0000	866.0000	1056.0000	743.0000	411.0000			543.0000	447.0000	768.0000
D-Malic acid	38813.0000	59230.0000	70292.0000	89266.0000	1429.0000		759.0000	32110.0000	17819.0000	17172.0000	65443.0000	44376.0000	46177.0000	135662.0000	199500.0000	131612.0000
D-Mannose 1	16323.0000	21530.0000	25257.0000	36263.0000		155.0000		28451.0000	23071.0000	43493.0000	25392.0000	21946.0000	23136.0000	657.0000	1499.0000	2627.0000
D-Mannose 2	1221.0000	1788.0000	1253.0000	1565.0000	297.0000	118.0000	253.0000		686.0000	472.0000		892.0000	989.0000	434.0000	503.0000	947.0000
D-ribose-5-phosphate	729.0000	1083.0000		1041.0000			416.0000	504.0000	577.0000			876.0000		649.0000		
D-threitol	11389.0000	25455.0000	20934.0000	22948.0000				75612.0000	59789.0000	9636.0000	8270.0000	8071.0000	9833.0000	19740.0000	29227.0000	26090.0000
Eicosane	470.0000	8639.0000		20321.0000			4032.0000	12576.0000	3019.0000	514.0000	11992.0000	1404.0000	6590.0000	19577.0000	2652.0000	10064.0000
Elaidic acid		14558.0000	16583.0000	19309.0000	2595.0000	1595.0000	12545.0000	16275.0000	15453.0000	5948.0000	9413.0000	7315.0000	14517.0000	11778.0000	8978.0000	17374.0000
Ergosterol	777.0000		2378.0000	14663.0000					2415.0000	1149.0000			510.0000	6857.0000	3454.0000	1609.0000
ethanolamine	51495.0000	56740.0000	4786.0000	4264.0000	34782.0000	34964.0000		59106.0000	49485.0000	51906.0000	44117.0000	31678.0000		73004.0000	109631.0000	79678.0000
Ethanolamine	243169.0000	359104.0000	424286.0000	541668.0000	223787.0000	244198.0000	501277.0000	409177.0000	327606.0000	354497.0000	286841.0000	255962.0000	321557.0000	328258.0000	620063.0000	397003.0000
Fructose-6-phosphate			1197.0000	3161.0000	386.0000	409.0000			2297.0000	2630.0000	2062.0000		966.0000		344.0000	1685.0000
Fumaric acid	15588.0000	24853.0000	28967.0000	33031.0000	6570.0000	7028.0000	8575.0000	17857.0000	12838.0000	16592.0000	18990.0000	13332.0000	21439.0000	35432.0000	49454.0000	48695.0000
GABA	441067.0000	740396.0000	904983.0000	1008784.0000	1180.0000	661.0000	2686.0000	630330.0000	433876.0000	415565.0000	281823.0000	255053.0000	341319.0000	614829.0000	1060323.0000	1055418.0000
Galactitol	9993.0000	16289.0000	20843.0000	25343.0000		494.0000		14020.0000	16097.0000	19784.0000			7130.0000	13213.0000	19030.0000	17579.0000
Galactonic acid	952.0000		895.0000	2390.0000		214.0000	353.0000	839.0000	790.0000	712.0000	1815.0000	1502.0000		1067.0000		2899.0000
Gluconic acid	1837.0000		1740.0000	2858.0000		171.0000		1968.0000	1493.0000	1146.0000		984.0000	925.0000			579.0000
Glucose 6-phosphate		890.0000		207.0000	775.0000		91.0000					1572.0000		426.0000		1773.0000
Glutamine	231030.0000	221455.0000	168744.0000	27657.0000	643.0000	366.0000	878.0000	131145.0000	129554.0000	94218.0000	22623.0000	12107.0000	10473.0000	42632.0000	2494.0000	22271.0000
Glutaric acid		177.0000	297.0000	350.0000	170.0000	218.0000	252.0000	178.0000	140.0000	487.0000	267.0000	211.0000		181.0000	215.0000	122.0000
Glutathione	142.0000		2061.0000		277.0000	699.0000					1454.0000					
Glycerol	5540762.0000	5784932.0000	7535964.0000	9228843.0000	18833.0000	51936.0000	41121.0000	8088790.0000	7864594.0000	9247029.0000	2861162.0000	3590085.0000	3801313.0000	14464339.0000	16586832.0000	15087282.0000
glycerol 3-phosphate	244.0000	2194.0000	3798.0000	4538.0000			144.0000	199.0000	857.0000	1212.0000	929.0000	925.0000	1087.0000	5178.0000	5114.0000	5459.0000
Glycine	132283.0000	234463.0000	248571.0000	305234.0000	1839.0000	2046.0000	2388.0000	187658.0000	163523.0000	149043.0000	177126.0000	131930.0000	199520.0000	546965.0000	656955.0000	596104.0000
Glycolic acid	17795.0000	20313.0000					37296.0000	29736.0000			20048.0000		24033.0000			22222.0000
Glyoxylic acid				4141.0000			184.0000									
Guanine	118.0000	682.0000	609.0000		147.0000		184.0000	286.0000	546.0000		222.0000	825.0000	734.0000	267.0000	420.0000	577.0000
Heptadecanoic acid					100599.0000		589.0000								2563.0000	
hexadecene				814.0000		1435.0000			935.0000	162.0000	2453.0000		2429.0000			808.0000
Histamine	2066.0000	2061.0000	3162.0000	8076.0000	76.0000	245.0000	409.0000							4426.0000	2783.0000	7753.0000
Hypotaurine	1411.0000	1685.0000	2416.0000	3143.0000		393.0000	473.0000	1880.0000			1345.0000	699.0000	861.0000	3940.0000	3076.0000	3345.0000
Hypoxanthine	54919.0000	66757.0000	82521.0000	115410.0000	610.0000	215.0000	405.0000	136592.0000	109383.0000	94506.0000	25057.0000	22709.0000	25868.0000	44761.0000	68501.0000	42811.0000
Iminodiacetic acid 	4287.0000	3903.0000	4742.0000	6175.0000	4945.0000	3384.0000	7353.0000	5607.0000	6885.0000	4919.0000	6251.0000	3762.0000	5734.0000	6659.0000	8949.0000	5597.0000
Inosine	23756.0000	18215.0000	16642.0000	27302.0000	276.0000	198.0000		17239.0000	14363.0000	36425.0000	21076.0000	3069.0000	22399.0000	6702.0000	12959.0000	23768.0000
Inosine 5^-monophosphate	283.0000						1544.0000			4479.0000	1477.0000		685.0000			765.0000
Inositol phosphate	166548.0000	173375.0000	225095.0000	400965.0000	139.0000	2076.0000	2614.0000	197833.0000	126790.0000	141094.0000	214805.0000	155544.0000	198810.0000	275455.0000	325989.0000	288033.0000
Isocitric acid			1282.0000	600.0000	417.0000	476.0000	608.0000	2191.0000	2359.0000	3352.0000	1267.0000	702.0000	334.0000	239.0000		
Isoxanthopterin			370.0000	285.0000			285.0000	158.0000	135.0000	214.0000	97.0000	211.0000	242.0000	278.0000	184.0000	345.0000
Kynurenic acid					162.0000		810.0000				330.0000					276.0000
L-Alanine 1	172.0000		576.0000			424.0000	642.0000		287.0000	92.0000		363.0000	395.0000	124.0000	232.0000	543.0000
L-Alanine 2	1551725.0000	2355022.0000	2591786.0000	2668829.0000	6500.0000	15147.0000	24620.0000	1330488.0000	1114273.0000	1064587.0000	268189.0000	242995.0000	304908.0000	975342.0000	1020012.0000	1378900.0000
lanthionine	5769.0000	6345.0000	8822.0000	11060.0000				10093.0000	5446.0000	25537.0000	11045.0000	6871.0000	5758.0000	3174.0000	5604.0000	14553.0000
L-Ascorbic acid	1998.0000	2200.0000		3369.0000	346.0000	216.0000	483.0000	1568.0000	1099.0000	10031.0000	2373.0000		2112.0000			4481.0000
L-Asparagine	21788.0000	28697.0000	39726.0000	31461.0000	361.0000			29178.0000	10337.0000	13822.0000	18638.0000	12443.0000	17245.0000	69112.0000	33512.0000	79041.0000
L-Aspartic acid 1	305056.0000	425686.0000	584166.0000	1106959.0000	2131.0000	3451.0000	8990.0000	378523.0000	265823.0000	267943.0000	304107.0000	192841.0000	365072.0000	423682.0000	964031.0000	458087.0000
L-Aspartic acid 2	6170249.0000	12679393.0000	14615846.0000	16627048.0000	1051.0000	3069.0000	3620.0000	7554094.0000	6923882.0000	5266443.0000	7132780.0000	4152232.0000	6817614.0000	16407868.0000	17378925.0000	16954663.0000
Lauric Acid	30582.0000	34531.0000	39267.0000	52401.0000	10098.0000	7490.0000	14389.0000	30210.0000	37171.0000	17094.0000	24345.0000	29888.0000	31450.0000	37520.0000	90295.0000	49046.0000
L-Dopa		928.0000		659.0000		738.0000						2076.0000	583.0000			
L-Glutamic acid	549568.0000	1152596.0000	1329429.0000	825345.0000	147.0000		266.0000	1014725.0000	840816.0000	600320.0000	597617.0000	364018.0000	539952.0000	1641660.0000	743843.0000	1607103.0000
L-gulonic acid gamma-lactone	540.0000	192.0000		343.0000	177.0000	92.0000	208.0000	288.0000	372.0000	379.0000		764.0000				
Linoleic acid	134.0000	792.0000		728.0000	143.0000		605.0000	1581.0000	906.0000		752.0000		922.0000		756.0000	513.0000
L-Isoleucine 1	181267.0000	168817.0000	201563.0000	346505.0000	247690.0000	235681.0000	697721.0000	191428.0000	177061.0000	199753.0000	208337.0000	163445.0000	172085.0000	201876.0000	474592.0000	237179.0000
L-Isoleucine 2	154065.0000	187716.0000	244379.0000	224659.0000				81655.0000	88936.0000	64360.0000	38513.0000	37867.0000	39800.0000	309434.0000	413052.0000	446270.0000
L-Kynurenine								898.0000		693.0000			361.0000	2047.0000	215.0000	679.0000
L-Lactic acid	123022.0000	94941.0000	119431.0000	126269.0000	45097.0000	33345.0000	61217.0000	138633.0000	151484.0000	106824.0000	76155.0000	74195.0000	89769.0000	161060.0000	288149.0000	219484.0000
L-Leucine 1	18835.0000	29922.0000	36827.0000	80978.0000		357.0000	1384.0000	13323.0000	11825.0000	8899.0000	16743.0000	13954.0000	17940.0000	33772.0000	76011.0000	45565.0000
L-Leucine 2	213607.0000	301801.0000	352820.0000	290762.0000	195.0000			103673.0000	113372.0000	70367.0000	183653.0000	164309.0000	182715.0000	407303.0000	509199.0000	600182.0000
L-Lysine 1	479.0000	338.0000		567.0000			233.0000	879.0000	373.0000		121.0000	358.0000	269.0000			
L-Lysine 2	5458260.0000	7743873.0000	9082883.0000	12942761.0000	433.0000	3096.0000	7287.0000	581437.0000	480523.0000	402204.0000	2823400.0000	2102669.0000	3066927.0000	8321794.0000	9596539.0000	7943755.0000
L-Methionine 1	3185.0000		1459.0000	525.0000	530.0000				2270.0000							977.0000
L-Methionine 2	98570.0000	158121.0000	182261.0000	188615.0000	1230.0000	1072.0000	740.0000	113354.0000	194463.0000	98954.0000	76797.0000	83353.0000	61918.0000	318047.0000	432244.0000	420388.0000
L-Phenylalanine 1	93624.0000	115415.0000	156091.0000	290483.0000	626.0000		1780.0000	44265.0000	39066.0000	31405.0000	19440.0000	21901.0000	25795.0000	135394.0000	398867.0000	184461.0000
L-Phenylalanine 2	89742.0000	136190.0000	158543.0000	170947.0000		777.0000		42006.0000	46273.0000	27930.0000	19080.0000	18085.0000	20623.0000	209071.0000	252962.0000	273764.0000
L-Proline 1	7152.0000	10713.0000	14201.0000	32354.0000	978.0000		3887.0000	15753.0000	10546.0000	11556.0000	4934.0000	2808.0000	4633.0000	21508.0000	28176.0000	26616.0000
L-Proline 2	59076.0000	93012.0000	110260.0000	88992.0000	709.0000			91796.0000	82244.0000	78351.0000	61560.0000	51743.0000	58571.0000	179031.0000	171161.0000	238001.0000
L-Serine 1	10654.0000	18013.0000	27472.0000	41741.0000				39017.0000	26964.0000	25813.0000	19338.0000	10027.0000	24726.0000	57805.0000	88544.0000	51383.0000
L-Serine 2	622707.0000	967425.0000	1203115.0000	1166457.0000	7253.0000	3792.0000	3207.0000	1437068.0000	1332213.0000	972122.0000	982534.0000	714641.0000	913457.0000	3846233.0000	3990515.0000	4583225.0000
L-Sorbose	7430.0000	11047.0000	14020.0000	19825.0000	164.0000	145.0000	174.0000	19976.0000	7136.0000	9894.0000	11690.0000	7050.0000	15353.0000	11111.0000	16391.0000	27860.0000
L-threonine	186938.0000	331476.0000	383254.0000	612524.0000	38777.0000	16961.0000	18039.0000	452144.0000	315904.0000	255932.0000	153280.0000	110408.0000	212469.0000	550334.0000	857459.0000	570512.0000
L-Threonine	336388.0000	501025.0000	619991.0000	627188.0000		418.0000	1253.0000	659336.0000	638241.0000	439769.0000	406184.0000	282538.0000	383059.0000	1273108.0000	1431776.0000	1470099.0000
L-Tryptophan	11400.0000	13775.0000	17243.0000	43002.0000	5723.0000	3834.0000	14102.0000	16750.0000	7976.0000	7985.0000	7586.0000	7551.0000	8368.0000	21685.0000	28760.0000	13219.0000
L-Tyrosine 1	7225.0000	14355.0000	18850.0000	20556.0000				2248.0000		2527.0000	2844.0000		3871.0000	5089.0000	16750.0000	7841.0000
L-Tyrosine 2	161922.0000	223728.0000	265445.0000	401567.0000	341.0000	213.0000	1896.0000	15838.0000	16570.0000	16995.0000	32982.0000	27228.0000	33840.0000	90283.0000	127767.0000	120023.0000
L-Valine 1	226629.0000	329643.0000	277737.0000	492595.0000			1317.0000	447506.0000	383184.0000	253025.0000	85010.0000	63273.0000	92493.0000	306583.0000	442530.0000	425714.0000
L-Valine 2	763851.0000	965100.0000	1285170.0000	1458961.0000	1514.0000	1171.0000	4363.0000	922117.0000	870653.0000	601445.0000	251122.0000	214151.0000	246674.0000	1343365.0000	1794486.0000	1826710.0000
Malonic acid	574.0000		707.0000		1002.0000	270.0000		1106.0000	588.0000	500.0000	652.0000	672.0000			481.0000	617.0000
methyl-beta-D-galactopyranoside	32106.0000			1863.0000	46.0000			24791.0000	20329.0000	21652.0000	10727.0000	6694.0000	10466.0000	22208.0000	3514.0000	
Myoinositol	295117.0000	420298.0000	474483.0000	682776.0000	121.0000	610.0000	148.0000	515375.0000	416091.0000	424246.0000	510831.0000	374448.0000	532731.0000	408219.0000	568305.0000	492346.0000
Myristic acid	481434.0000	618485.0000	645253.0000	896190.0000	391123.0000	340965.0000	797919.0000	559436.0000	394126.0000	352513.0000	373424.0000	291356.0000	341587.0000	700587.0000	1258100.0000	599734.0000
Myristic Acid d27				192.0000	300.0000					768.0000	5060.0000	894.0000	808.0000			
N-acetyl-L-aspartic acid 1				1799.0000			591.0000	2079.0000	2429.0000		2699.0000			1605.0000	1721.0000	5522.0000
N-acetyl-L-aspartic acid 2	465.0000		806.0000	357.0000			154.0000	199.0000	146.0000	512.0000	187.0000	125.0000	200.0000	89.0000		691.0000
Nicotinamide	112548.0000	135394.0000	159994.0000	235176.0000	1174.0000	1753.0000		127055.0000	132317.0000	113791.0000	102220.0000	119751.0000	97721.0000	167057.0000	348237.0000	169251.0000
Nitrous Oxide	440199.0000	430661.0000	417892.0000	421092.0000	437272.0000	328356.0000	223220.0000	376762.0000	352392.0000	373349.0000	390344.0000	339448.0000	367500.0000	487386.0000	609027.0000	366190.0000
N-methylalanine	4811.0000	19308.0000	4480.0000	4056.0000	6879.0000	14640.0000	5620.0000	11805.0000	10929.0000	14933.0000	8287.0000	4846.0000	5382.0000	9133.0000	5984.0000	10907.0000
nonanoic acid	207374.0000	204547.0000	248481.0000	308350.0000	148310.0000	181269.0000	296831.0000	235303.0000	200885.0000	206684.0000	165626.0000	172104.0000	186240.0000	229472.0000	532341.0000	209953.0000
Oleic acid	26396.0000	9357.0000	35239.0000	23279.0000	6560.0000	40332.0000	48107.0000	69304.0000	35843.0000	53883.0000	23730.0000	53137.0000	5823.0000	10148.0000	87554.0000	67599.0000
O-Phosphoethanolamine	295.0000	753.0000	302.0000	1484.0000	687.0000	123.0000	549.0000		712.0000	211.0000	765.0000	403.0000	532.0000	454.0000	632.0000	
Ornithine	779942.0000	999970.0000	1176297.0000	1413765.0000		949.0000	3559.0000	538456.0000	495926.0000	392681.0000	103864.0000	89207.0000	113953.0000	403503.0000	445095.0000	390223.0000
Oxalic acid	20373.0000	35884.0000	34948.0000	36186.0000	24958.0000	41329.0000	55968.0000	47544.0000	39264.0000	38135.0000	24950.0000	22632.0000	31370.0000	27576.0000	46480.0000	32805.0000
Palmitic acid	12794470.0000	13817801.0000	13742224.0000	17450002.0000	4610022.0000	3971181.0000	9818386.0000	13266117.0000	11751144.0000	11005479.0000	13937672.0000	10100699.0000	12050721.0000	13719873.0000	18149076.0000	13940063.0000
Palmitoleic acid	25490.0000	147944.0000	165278.0000	271177.0000	32944.0000	82557.0000	161030.0000	171693.0000	69313.0000	145309.0000	100438.0000	136465.0000	66789.0000	109943.0000	251754.0000	80835.0000
Pantothenic acid		206.0000		493.0000				580.0000	197.0000	1001.0000	89.0000	357.0000	120.0000	196.0000		
Pectin	3768.0000	4618.0000	7459.0000	8918.0000		699.0000	218.0000	7836.0000	3481.0000	9560.0000	7048.0000	7531.0000	8442.0000	2282.0000	6344.0000	7013.0000
Phosphate	12324853.0000	18042923.0000	19189140.0000	21850193.0000	118054.0000	121256.0000	255950.0000	19986755.0000	19980637.0000	19259543.0000	16481745.0000	15065572.0000	18678524.0000	20945319.0000	24681547.0000	22483864.0000
Phosphatidyl Glycerol					625.0000	364.0000	131.0000	1626.0000		330.0000			589.0000			
Phosphoenolpyruvate	325.0000						66.0000	457.0000		428.0000		809.0000	218.0000			
picolonic acid	379.0000			310.0000	277.0000		1351.0000			831.0000			504.0000			
Putrescine	773.0000		799.0000							594.0000			860.0000			1154.0000
Pyroglutamic acid	2337729.0000	4974602.0000	6352141.0000	10873160.0000	1509.0000	3479.0000	7996.0000	4458896.0000	3289071.0000	2929395.0000	1258104.0000	864217.0000	1439647.0000	2612560.0000	7021752.0000	2882643.0000
Pyrophosphate	150.0000					288.0000	234.0000	348.0000							299.0000	
Pyrrolidonecarboxylic acid	11469.0000	15138.0000	17283.0000	36751.0000	947.0000			17223.0000	11597.0000		6307.0000	7275.0000	8342.0000	9244.0000	26445.0000	15719.0000
Pyruvic acid	7237.0000	10126.0000	14082.0000	18300.0000	2650.0000			12243.0000	8139.0000	9524.0000	6496.0000	7122.0000	8462.0000	9986.0000	18566.0000	16366.0000
Ribitol	1885.0000	908.0000	2535.0000	4140.0000	284.0000			2061.0000	2953.0000	2686.0000	174.0000	672.0000	1267.0000	1706.0000	4807.0000	3508.0000
ribonic acid-gamma-lactone	738.0000	1130.0000	1207.0000	1356.0000				1529.0000	1106.0000	1230.0000	1568.0000	969.0000	1312.0000	1430.0000	1870.0000	
Sarcosine	13062.0000	20203.0000	20177.0000	9988.0000	21232.0000	13542.0000	10128.0000	21716.0000	18819.0000	24728.0000	14957.0000	13810.0000	17237.0000	4104.0000	5335.0000	21448.0000
Sedoheptulose 7-phosphate	1806.0000	1096.0000	1763.0000	965.0000	160.0000			5548.0000	4354.0000	1586.0000	2520.0000	3064.0000	3665.0000		289.0000	1945.0000
Serotonin 1		1098.0000	2149.0000	405.0000		364.0000	47.0000		384.0000		1789.0000		2212.0000	989.0000	3414.0000	3709.0000
Serotonin 2				925.0000							375.0000	247.0000		489.0000		
sophorose			648.0000		842.0000										1135.0000	
Sorbitol	112005.0000	147978.0000	175648.0000	242291.0000	118.0000	723.0000	851.0000	183668.0000	114995.0000	145908.0000	51434.0000	26531.0000	34422.0000	45401.0000	62749.0000	55263.0000
Spermidine	722.0000		383.0000		243.0000							2017.0000			1472.0000	789.0000
Stearic acid	10239324.0000	11375283.0000	12241435.0000	16020709.0000	7449868.0000	6361277.0000	14004966.0000	12131087.0000	6781391.0000	6431397.0000	12389713.0000	6701385.0000	8447487.0000	13029447.0000	15567814.0000	11033773.0000
Succinic acid	77141.0000	123955.0000	150668.0000	187404.0000	2709.0000	5338.0000	5231.0000	183204.0000	147515.0000	152499.0000	169978.0000	145131.0000	164637.0000	308665.0000	440269.0000	385296.0000
Tartaric Acid	4200.0000	8563.0000	9342.0000	10661.0000		346.0000	355.0000	10364.0000	8428.0000	4594.0000	2438.0000	1529.0000	2794.0000	5822.0000	5180.0000	8066.0000
Taurine	620.0000	2639.0000	619.0000	888.0000	1284.0000	613.0000	465.0000	2225.0000	1881.0000	840.0000	1360.0000	792.0000	1572.0000	1598.0000	1249.0000	2743.0000
threonic acid	27211.0000	80451.0000	92760.0000	127257.0000		148.0000	1137.0000	132843.0000	28548.0000	20957.0000	85855.0000	30365.0000	117822.0000	97021.0000	116529.0000	168923.0000
threose						298.0000	170.0000		217.0000	83.0000	146.0000	655.0000			282.0000	1040.0000
Thymine				1527.0000									1219.0000		327.0000	
turanose					365.0000	248.0000										
Uracil	173483.0000	227589.0000	272652.0000	324337.0000	23628.0000	6835.0000	8266.0000	168701.0000	187792.0000	168763.0000	204456.0000	176304.0000	201660.0000	289650.0000	508230.0000	317734.0000
Urea	46512.0000	54789.0000	66184.0000	59188.0000	34832.0000	34859.0000	34817.0000	68096.0000	57582.0000	59456.0000	32786.0000	35954.0000	38568.0000	78829.0000	127749.0000	83112.0000
Uric acid 1	383.0000		227.0000	135.0000		133.0000	164.0000	406.0000		574.0000		141.0000		145.0000	537.0000	1108.0000
Uric acid 2	461.0000			109.0000		793.0000					78.0000		1254.0000	796.0000		160.0000
uridine	4679.0000	19414.0000	22555.0000	37656.0000	224.0000	216.0000		8730.0000	11527.0000	13450.0000	3882.0000	5258.0000	683.0000	9280.0000	20998.0000	13980.0000
Uridine 5^-monophosphate	10691.0000	4722.0000		13823.0000	1128.0000	167.0000	513.0000	4232.0000	2184.0000	1804.0000	3327.0000	2305.0000	2590.0000	7109.0000	9019.0000	
Xanthine	5585.0000	7671.0000	9943.0000	14335.0000	659.0000	276.0000	396.0000	4469.0000	5136.0000	5411.0000		1422.0000	1389.0000	7715.0000	10124.0000	9947.0000
Xanthurenic acid		152.0000	505.0000	120.0000	264.0000			189.0000				286.0000	915.0000	797.0000	557.0000	
xylose		3415.0000	4761.0000	6973.0000				4623.0000	1898.0000	155.0000	2397.0000	815.0000	6280.0000		4434.0000	10157.0000
MS_METABOLITE_DATA_END
#METABOLITES
METABOLITES_START
metabolite_name	pubchem_id	inchi_key	kegg_id	other_id	other_id_type	ri	ri_type	moverz_quant	
1,6-anhydro-glucose									
1-monomyristin									
1-octadecene									
1-Palmitoylglycerol									
1-Steroylglycerol									
2'3'-Bisphosphoglycerate									
2-Hydroxybenzoic acid									
2-Hydroxybutyric acid 2									
2-Hydroxyglutaric acid 1									
2-ketoglutarate									
2-Ketoisocaproic acid									
2-monopalmitoylglycerol									
2-Steroylglycerol									
3-hydroxybutyric acid									
3-Phosphoglyceric acid									
4-Hydroxyproline 1									
4-Hydroxyproline 2									
5-hydroxytryptophan									
Adenine									
Adenosine									
Adenosine monophosphate									
Adipic acid									
Allantoin									
alpha-D-glucosamine 1-phosphate									
Aminoadipic acid									
Arachidic acid									
Arachidonic Acid									
azelaic acid									
Benzoic acid									
Benzoquinone									
Beta-Alanine									
Beta-Glycerophosphoric acid									
Beta-lactate									
Beta-Sitosterol									
Capric acid									
Cellobiose									
Cholesterol									
cis-Aconitic acid									
Citric acid									
Creatinine									
Cystathionine									
d4-succinate									
Dehydroascorbic acid									
delta Amino Levulinic acid									
D-Fructose 1									
D-Fructose 2									
D-Galactose									
D-glucose 1									
D-glucose 2									
DHAP									
Diethyl Phthalate									
Diglycerol									
DL-3-Aminoisobutyric acid									
D-Malic acid									
D-Mannose 1									
D-Mannose 2									
D-ribose-5-phosphate									
D-threitol									
Eicosane									
Elaidic acid									
Ergosterol									
ethanolamine									
Ethanolamine									
Fructose-6-phosphate									
Fumaric acid									
GABA									
Galactitol									
Galactonic acid									
Gluconic acid									
Glucose 6-phosphate									
Glutamine									
Glutaric acid									
Glutathione									
Glycerol									
glycerol 3-phosphate									
Glycine									
Glycolic acid									
Glyoxylic acid									
Guanine									
Heptadecanoic acid									
hexadecene									
Histamine									
Hypotaurine									
Hypoxanthine									
Iminodiacetic acid 									
Inosine									
Inosine 5'-monophosphate									
Inositol phosphate									
Isocitric acid									
Isoxanthopterin									
Kynurenic acid									
L-Alanine 1									
L-Alanine 2									
lanthionine									
L-Ascorbic acid									
L-Asparagine									
L-Aspartic acid 1									
L-Aspartic acid 2									
Lauric Acid									
L-Dopa									
L-Glutamic acid									
L-gulonic acid gamma-lactone									
Linoleic acid									
L-Isoleucine 1									
L-Isoleucine 2									
L-Kynurenine									
L-Lactic acid									
L-Leucine 1									
L-Leucine 2									
L-Lysine 1									
L-Lysine 2									
L-Methionine 1									
L-Methionine 2									
L-Phenylalanine 1									
L-Phenylalanine 2									
L-Proline 1									
L-Proline 2									
L-Serine 1									
L-Serine 2									
L-Sorbose									
L-threonine									
L-Threonine									
L-Tryptophan									
L-Tyrosine 1									
L-Tyrosine 2									
L-Valine 1									
L-Valine 2									
Malonic acid									
methyl-beta-D-galactopyranoside									
Myoinositol									
Myristic acid									
Myristic Acid d27									
N-acetyl-L-aspartic acid 1									
N-acetyl-L-aspartic acid 2									
Nicotinamide									
Nitrous Oxide									
N-methylalanine									
nonanoic acid									
Oleic acid									
O-Phosphoethanolamine									
Ornithine									
Oxalic acid									
Palmitic acid									
Palmitoleic acid									
Pantothenic acid									
Pectin									
Phosphate									
Phosphatidyl Glycerol									
Phosphoenolpyruvate									
picolonic acid									
Putrescine									
Pyroglutamic acid									
Pyrophosphate									
Pyrrolidonecarboxylic acid									
Pyruvic acid									
Ribitol									
ribonic acid-gamma-lactone									
Sarcosine									
Sedoheptulose 7-phosphate									
Serotonin 1									
Serotonin 2									
sophorose									
Sorbitol									
Spermidine									
Stearic acid									
Succinic acid									
Tartaric Acid									
Taurine									
threonic acid									
threose									
Thymine									
turanose									
Uracil									
Urea									
Uric acid 1									
Uric acid 2									
uridine									
Uridine 5'-monophosphate									
Xanthine									
Xanthurenic acid									
xylose									
METABOLITES_END
#END