#METABOLOMICS WORKBENCH lamccall_20221023_091713 DATATRACK_ID:3533 STUDY_ID:ST002347 ANALYSIS_ID:AN003832 PROJECT_ID:PR001507
VERSION             	1
CREATED_ON             	November 15, 2022, 8:53 am
#PROJECT
PR:PROJECT_TITLE                 	Impact of Visceral Leishmaniasis on Local Organ Metabolism in Hamsters
PR:PROJECT_SUMMARY               	Leishmania is an intracellular parasite with different species pathogenic to
PR:PROJECT_SUMMARY               	humans and causing the disease leishmaniasis. Leishmania donovani causes
PR:PROJECT_SUMMARY               	visceral leishmaniasis (VL) that manifests as hepatosplenomegaly, fever,
PR:PROJECT_SUMMARY               	pancytopenia and hypergammaglobulinemia. If left without treatment, VL can cause
PR:PROJECT_SUMMARY               	death, especially in immunocompromised people. Current treatments have often
PR:PROJECT_SUMMARY               	significant adverse effects, and resistance has been reported in some countries.
PR:PROJECT_SUMMARY               	Determining the metabolites perturbed during VL can lead us to find new
PR:PROJECT_SUMMARY               	treatments targeting disease pathogenesis. We therefore compared metabolic
PR:PROJECT_SUMMARY               	perturbation between L. donovani-infected and uninfected hamsters across organs
PR:PROJECT_SUMMARY               	(spleen, liver, and gut). Metabolites were extracted, analyzed by liquid
PR:PROJECT_SUMMARY               	chromatography-mass spectrometry, and processed with MZmine and molecular
PR:PROJECT_SUMMARY               	networking to annotate metabolites. We found few metabolites commonly impacted
PR:PROJECT_SUMMARY               	by infection across all three sites, including glycerophospholipids, ceramides,
PR:PROJECT_SUMMARY               	acylcarnitines, peptides, purines and amino acids. In accordance with VL
PR:PROJECT_SUMMARY               	symptoms and parasite tropism, we found a greater overlap of perturbed
PR:PROJECT_SUMMARY               	metabolites between spleen and liver compared to spleen and gut, or liver and
PR:PROJECT_SUMMARY               	gut. Targeting pathways related to these metabolite families would be the next
PR:PROJECT_SUMMARY               	focus that can lead us to find more effective treatments for VL.
PR:INSTITUTE                     	University of Oklahoma
PR:LAST_NAME                     	McCall
PR:FIRST_NAME                    	Laura-Isobel
PR:ADDRESS                       	101 Stephenson Pkwy, Norman, OK, 73019-5251, USA
PR:EMAIL                         	lmccall@ou.edu
PR:PHONE                         	4053259385
#STUDY
ST:STUDY_TITLE                   	Impact of Visceral Leishmaniasis on Local Organ Metabolism in Hamsters
ST:STUDY_SUMMARY                 	Leishmania is an intracellular parasite with different species pathogenic to
ST:STUDY_SUMMARY                 	humans and causing the disease leishmaniasis. Leishmania donovani causes
ST:STUDY_SUMMARY                 	visceral leishmaniasis (VL) that manifests as hepatosplenomegaly, fever,
ST:STUDY_SUMMARY                 	pancytopenia and hypergammaglobulinemia. If left without treatment, VL can cause
ST:STUDY_SUMMARY                 	death, especially in immunocompromised people. Current treatments have often
ST:STUDY_SUMMARY                 	significant adverse effects, and resistance has been reported in some countries.
ST:STUDY_SUMMARY                 	Determining the metabolites perturbed during VL can lead us to find new
ST:STUDY_SUMMARY                 	treatments targeting disease pathogenesis. We therefore compared metabolic
ST:STUDY_SUMMARY                 	perturbation between L. donovani-infected and uninfected hamsters across organs
ST:STUDY_SUMMARY                 	(spleen, liver, and gut). Metabolites were extracted, analyzed by liquid
ST:STUDY_SUMMARY                 	chromatography-mass spectrometry, and processed with MZmine and molecular
ST:STUDY_SUMMARY                 	networking to annotate metabolites. We found few metabolites commonly impacted
ST:STUDY_SUMMARY                 	by infection across all three sites, including glycerophospholipids, ceramides,
ST:STUDY_SUMMARY                 	acylcarnitines, peptides, purines and amino acids. In accordance with VL
ST:STUDY_SUMMARY                 	symptoms and parasite tropism, we found a greater overlap of perturbed
ST:STUDY_SUMMARY                 	metabolites between spleen and liver compared to spleen and gut, or liver and
ST:STUDY_SUMMARY                 	gut. Targeting pathways related to these metabolite families would be the next
ST:STUDY_SUMMARY                 	focus that can lead us to find more effective treatments for VL.
ST:INSTITUTE                     	University of Oklahoma
ST:LAST_NAME                     	McCall
ST:FIRST_NAME                    	Laura-Isobel
ST:ADDRESS                       	101 Stephenson Pkwy, Norman, OK, 73019-5251, USA
ST:EMAIL                         	lmccall@ou.edu
ST:NUM_GROUPS                    	2
ST:TOTAL_SUBJECTS                	14-16
ST:PUBLICATIONS                  	https://doi.org/10.3390/metabo12090802
ST:PHONE                         	4053259385
#SUBJECT
SU:SUBJECT_TYPE                  	Mammal
SU:SUBJECT_SPECIES               	Mesocricetus auratus
#SUBJECT_SAMPLE_FACTORS:         	SUBJECT(optional)[tab]SAMPLE[tab]FACTORS(NAME:VALUE pairs separated by |)[tab]Raw file names and additional sample data
SUBJECT_SAMPLE_FACTORS           	QC	pos_pooled_QC1.mzXML	organ:QC | experiment:QC | group:QC	endpoint.dpi=QC; delta_weight=QC; liver_weight=QC; spleen_weight=QC; liver_load=QC; spleen_load=QC; RAW_FILE_NAME=pos_pooled_QC1.raw
SUBJECT_SAMPLE_FACTORS           	QC	pos_pooled_QC2.mzXML	organ:QC | experiment:QC | group:QC	endpoint.dpi=QC; delta_weight=QC; liver_weight=QC; spleen_weight=QC; liver_load=QC; spleen_load=QC; RAW_FILE_NAME=pos_pooled_QC2.raw
SUBJECT_SAMPLE_FACTORS           	QC	pos_pooled_QC2_20200813232930.mzXML	organ:QC | experiment:QC | group:QC	endpoint.dpi=QC; delta_weight=QC; liver_weight=QC; spleen_weight=QC; liver_load=QC; spleen_load=QC; RAW_FILE_NAME=pos_pooled_QC2_20200813232930.raw
SUBJECT_SAMPLE_FACTORS           	QC	pos_pooled_QC2_20200814012600.mzXML	organ:QC | experiment:QC | group:QC	endpoint.dpi=QC; delta_weight=QC; liver_weight=QC; spleen_weight=QC; liver_load=QC; spleen_load=QC; RAW_FILE_NAME=pos_pooled_QC2_20200814012600.raw
SUBJECT_SAMPLE_FACTORS           	QC	pos_pooled_QC2_20200814032229.mzXML	organ:QC | experiment:QC | group:QC	endpoint.dpi=QC; delta_weight=QC; liver_weight=QC; spleen_weight=QC; liver_load=QC; spleen_load=QC; RAW_FILE_NAME=pos_pooled_QC2_20200814032229.raw
SUBJECT_SAMPLE_FACTORS           	QC	pos_pooled_QC2_20200814051904.mzXML	organ:QC | experiment:QC | group:QC	endpoint.dpi=QC; delta_weight=QC; liver_weight=QC; spleen_weight=QC; liver_load=QC; spleen_load=QC; RAW_FILE_NAME=pos_pooled_QC2_20200814051904.raw
SUBJECT_SAMPLE_FACTORS           	QC	pos_pooled_QC2_20200814071541.mzXML	organ:QC | experiment:QC | group:QC	endpoint.dpi=QC; delta_weight=QC; liver_weight=QC; spleen_weight=QC; liver_load=QC; spleen_load=QC; RAW_FILE_NAME=pos_pooled_QC2_20200814071541.raw
SUBJECT_SAMPLE_FACTORS           	QC	pos_pooled_QC2_20200814091220.mzXML	organ:QC | experiment:QC | group:QC	endpoint.dpi=QC; delta_weight=QC; liver_weight=QC; spleen_weight=QC; liver_load=QC; spleen_load=QC; RAW_FILE_NAME=pos_pooled_QC2_20200814091220.raw
SUBJECT_SAMPLE_FACTORS           	QC	pos_pooled_QC2_20200814110901.mzXML	organ:QC | experiment:QC | group:QC	endpoint.dpi=QC; delta_weight=QC; liver_weight=QC; spleen_weight=QC; liver_load=QC; spleen_load=QC; RAW_FILE_NAME=pos_pooled_QC2_20200814110901.raw
SUBJECT_SAMPLE_FACTORS           	QC	pos_pooled_QC2_20200814131354.mzXML	organ:QC | experiment:QC | group:QC	endpoint.dpi=QC; delta_weight=QC; liver_weight=QC; spleen_weight=QC; liver_load=QC; spleen_load=QC; RAW_FILE_NAME=pos_pooled_QC2_20200814131354.raw
SUBJECT_SAMPLE_FACTORS           	QC	pos_pooled_QC2_20200814151041.mzXML	organ:QC | experiment:QC | group:QC	endpoint.dpi=QC; delta_weight=QC; liver_weight=QC; spleen_weight=QC; liver_load=QC; spleen_load=QC; RAW_FILE_NAME=pos_pooled_QC2_20200814151041.raw
SUBJECT_SAMPLE_FACTORS           	QC	pos_pooled_QC3.mzXML	organ:QC | experiment:QC | group:QC	endpoint.dpi=QC; delta_weight=QC; liver_weight=QC; spleen_weight=QC; liver_load=QC; spleen_load=QC; RAW_FILE_NAME=pos_pooled_QC3.raw
SUBJECT_SAMPLE_FACTORS           	QC	pos_pooled_QC4.mzXML	organ:QC | experiment:QC | group:QC	endpoint.dpi=QC; delta_weight=QC; liver_weight=QC; spleen_weight=QC; liver_load=QC; spleen_load=QC; RAW_FILE_NAME=pos_pooled_QC4.raw
SUBJECT_SAMPLE_FACTORS           	QC	pos_pooled_QC5.mzXML	organ:QC | experiment:QC | group:QC	endpoint.dpi=QC; delta_weight=QC; liver_weight=QC; spleen_weight=QC; liver_load=QC; spleen_load=QC; RAW_FILE_NAME=pos_pooled_QC5.raw
SUBJECT_SAMPLE_FACTORS           	blank	Start_blank.mzXML	organ:blank | experiment:blank | group:blank	endpoint.dpi=blank; delta_weight=blank; liver_weight=blank; spleen_weight=blank; liver_load=blank; spleen_load=blank; RAW_FILE_NAME=Start_blank.raw
SUBJECT_SAMPLE_FACTORS           	blank	Start_blank_20200813204327.mzXML	organ:blank | experiment:blank | group:blank	endpoint.dpi=blank; delta_weight=blank; liver_weight=blank; spleen_weight=blank; liver_load=blank; spleen_load=blank; RAW_FILE_NAME=Start_blank_20200813204327.raw
SUBJECT_SAMPLE_FACTORS           	blank	Start_blank_20200813232118.mzXML	organ:blank | experiment:blank | group:blank	endpoint.dpi=blank; delta_weight=blank; liver_weight=blank; spleen_weight=blank; liver_load=blank; spleen_load=blank; RAW_FILE_NAME=Start_blank_20200813232118.raw
SUBJECT_SAMPLE_FACTORS           	blank	Start_blank_20200814011747.mzXML	organ:blank | experiment:blank | group:blank	endpoint.dpi=blank; delta_weight=blank; liver_weight=blank; spleen_weight=blank; liver_load=blank; spleen_load=blank; RAW_FILE_NAME=Start_blank_20200814011747.raw
SUBJECT_SAMPLE_FACTORS           	blank	Start_blank_20200814031416.mzXML	organ:blank | experiment:blank | group:blank	endpoint.dpi=blank; delta_weight=blank; liver_weight=blank; spleen_weight=blank; liver_load=blank; spleen_load=blank; RAW_FILE_NAME=Start_blank_20200814031416.raw
SUBJECT_SAMPLE_FACTORS           	blank	Start_blank_20200814051051.mzXML	organ:blank | experiment:blank | group:blank	endpoint.dpi=blank; delta_weight=blank; liver_weight=blank; spleen_weight=blank; liver_load=blank; spleen_load=blank; RAW_FILE_NAME=Start_blank_20200814051051.raw
SUBJECT_SAMPLE_FACTORS           	blank	Start_blank_20200814070728.mzXML	organ:blank | experiment:blank | group:blank	endpoint.dpi=blank; delta_weight=blank; liver_weight=blank; spleen_weight=blank; liver_load=blank; spleen_load=blank; RAW_FILE_NAME=Start_blank_20200814070728.raw
SUBJECT_SAMPLE_FACTORS           	blank	Start_blank_20200814090407.mzXML	organ:blank | experiment:blank | group:blank	endpoint.dpi=blank; delta_weight=blank; liver_weight=blank; spleen_weight=blank; liver_load=blank; spleen_load=blank; RAW_FILE_NAME=Start_blank_20200814090407.raw
SUBJECT_SAMPLE_FACTORS           	blank	Start_blank_20200814110048.mzXML	organ:blank | experiment:blank | group:blank	endpoint.dpi=blank; delta_weight=blank; liver_weight=blank; spleen_weight=blank; liver_load=blank; spleen_load=blank; RAW_FILE_NAME=Start_blank_20200814110048.raw
SUBJECT_SAMPLE_FACTORS           	blank	Start_blank_20200814125728.mzXML	organ:blank | experiment:blank | group:blank	endpoint.dpi=blank; delta_weight=blank; liver_weight=blank; spleen_weight=blank; liver_load=blank; spleen_load=blank; RAW_FILE_NAME=Start_blank_20200814125728.raw
SUBJECT_SAMPLE_FACTORS           	blank	Start_blank_20200814150228.mzXML	organ:blank | experiment:blank | group:blank	endpoint.dpi=blank; delta_weight=blank; liver_weight=blank; spleen_weight=blank; liver_load=blank; spleen_load=blank; RAW_FILE_NAME=Start_blank_20200814150228.raw
SUBJECT_SAMPLE_FACTORS           	blank	Start_blank_20200814163404.mzXML	organ:blank | experiment:blank | group:blank	endpoint.dpi=blank; delta_weight=blank; liver_weight=blank; spleen_weight=blank; liver_load=blank; spleen_load=blank; RAW_FILE_NAME=Start_blank_20200814163404.raw
SUBJECT_SAMPLE_FACTORS           	16100	X16100_Ld1s_plus_ABX_gut_P80.mzXML	organ:gut | experiment:AB4 | group:Ld1s_plus ABX	endpoint.dpi=87; delta_weight=21.98; liver_weight=5.916; spleen_weight=0.524; liver_load=4.44E+07; spleen_load=8.06E+08; RAW_FILE_NAME=16100_Ld1s_plus_ABX_gut_P80.raw
SUBJECT_SAMPLE_FACTORS           	16100	X16100_Ld1s_plus_ABX_liver_P80.mzXML	organ:liver | experiment:AB4 | group:Ld1s_plus ABX	endpoint.dpi=87; delta_weight=21.98; liver_weight=5.916; spleen_weight=0.524; liver_load=4.44E+07; spleen_load=8.06E+08; RAW_FILE_NAME=16100_Ld1s_plus_ABX_liver_P80.raw
SUBJECT_SAMPLE_FACTORS           	16100	X16100_Ld1s_plus_ABX_spleen_P80_1.mzXML	organ:spleen | experiment:AB4 | group:Ld1s_plus ABX	endpoint.dpi=87; delta_weight=21.98; liver_weight=5.916; spleen_weight=0.524; liver_load=4.44E+07; spleen_load=8.06E+08; RAW_FILE_NAME=16100_Ld1s_plus_ABX_spleen_P80_1.raw
SUBJECT_SAMPLE_FACTORS           	16100	X16100_Ld1s_plus_ABX_spleen_P80_2.mzXML	organ:spleen | experiment:AB4 | group:Ld1s_plus ABX	endpoint.dpi=87; delta_weight=21.98; liver_weight=5.916; spleen_weight=0.524; liver_load=4.44E+07; spleen_load=8.06E+08; RAW_FILE_NAME=16100_Ld1s_plus_ABX_spleen_P80_2.raw
SUBJECT_SAMPLE_FACTORS           	16101	X16101_Ld1s_plus_ABX_gut_P80.mzXML	organ:gut | experiment:AB4 | group:Ld1s_plus ABX	endpoint.dpi=87; delta_weight=27; liver_weight=7.432; spleen_weight=0.754; liver_load=6.50E+07; spleen_load=6.10E+08; RAW_FILE_NAME=16101_Ld1s_plus_ABX_gut_P80.raw
SUBJECT_SAMPLE_FACTORS           	16101	X16101_Ld1s_plus_ABX_spleen_P80_1.mzXML	organ:spleen | experiment:AB4 | group:Ld1s_plus ABX	endpoint.dpi=87; delta_weight=27; liver_weight=7.432; spleen_weight=0.754; liver_load=6.50E+07; spleen_load=6.10E+08; RAW_FILE_NAME=16101_Ld1s_plus_ABX_spleen_P80_1.raw
SUBJECT_SAMPLE_FACTORS           	16101	X16101_Ld1s_plus_ABX_spleen_P80_2.mzXML	organ:spleen | experiment:AB4 | group:Ld1s_plus ABX	endpoint.dpi=87; delta_weight=27; liver_weight=7.432; spleen_weight=0.754; liver_load=6.50E+07; spleen_load=6.10E+08; RAW_FILE_NAME=16101_Ld1s_plus_ABX_spleen_P80_2.raw
SUBJECT_SAMPLE_FACTORS           	16.64	X1664_Ld1s_plus_ABX_spleen_P79.mzXML	organ:spleen | experiment:AB3 | group:Ld1s_plus ABX	endpoint.dpi=91; delta_weight=20.95; liver_weight=5.977; spleen_weight=0.554; liver_load=-; spleen_load=-; RAW_FILE_NAME=1664_Ld1s_plus_ABX_spleen_P79.raw
SUBJECT_SAMPLE_FACTORS           	16.65	X1665_Ld1s_plus_ABX_spleen_P79.mzXML	organ:spleen | experiment:AB3 | group:Ld1s_plus ABX	endpoint.dpi=91; delta_weight=28.16; liver_weight=6.2; spleen_weight=0.755; liver_load=-; spleen_load=-; RAW_FILE_NAME=1665_Ld1s_plus_ABX_spleen_P79.raw
SUBJECT_SAMPLE_FACTORS           	16.66	X1666_Ld1s_plus_ABX_spleen_P79.mzXML	organ:spleen | experiment:AB3 | group:Ld1s_plus ABX	endpoint.dpi=91; delta_weight=15.6; liver_weight=5.269; spleen_weight=0.823; liver_load=-; spleen_load=-; RAW_FILE_NAME=1666_Ld1s_plus_ABX_spleen_P79.raw
SUBJECT_SAMPLE_FACTORS           	16.67	X1667_Ld1s_plus_ABX_spleen_P79.mzXML	organ:spleen | experiment:AB3 | group:Ld1s_plus ABX	endpoint.dpi=95; delta_weight=25.26; liver_weight=5.271; spleen_weight=0.573; liver_load=7.54E+07; spleen_load=1.25E+09; RAW_FILE_NAME=1667_Ld1s_plus_ABX_spleen_P79.raw
SUBJECT_SAMPLE_FACTORS           	16.68	X1668_Ld1s_spleen_P79.mzXML	organ:spleen | experiment:AB3 | group:Ld1s	endpoint.dpi=95; delta_weight=3.91; liver_weight=8.204; spleen_weight=0.878; liver_load=7.91E+08; spleen_load=1.48E+09; RAW_FILE_NAME=1668_Ld1s_spleen_P79.raw
SUBJECT_SAMPLE_FACTORS           	16.69	X1669_Ld1s_spleen_P79.mzXML	organ:spleen | experiment:AB3 | group:Ld1s	endpoint.dpi=95; delta_weight=-3.88; liver_weight=6.946; spleen_weight=1.038; liver_load=1.09E+09; spleen_load=1.62E+09; RAW_FILE_NAME=1669_Ld1s_spleen_P79.raw
SUBJECT_SAMPLE_FACTORS           	16.7	X1670_Ld1s_plus_ABX_spleen_P79.mzXML	organ:spleen | experiment:AB3 | group:Ld1s_plus ABX	endpoint.dpi=96; delta_weight=5.71; liver_weight=5.648; spleen_weight=0.7; liver_load=5.81E+08; spleen_load=5.00E+09; RAW_FILE_NAME=1670_Ld1s_plus_ABX_spleen_P79.raw
SUBJECT_SAMPLE_FACTORS           	16.71	X1671_Naive_plus_ABX_spleen_P79.mzXML	organ:spleen | experiment:AB3 | group:Naive_plus ABX	endpoint.dpi=96; delta_weight=-; liver_weight=4.37; spleen_weight=0.097; liver_load=-; spleen_load=-; RAW_FILE_NAME=1671_Naive_plus_ABX_spleen_P79.raw
SUBJECT_SAMPLE_FACTORS           	1686	X1686_Naive_plus_ABX_gut_P79.mzXML	organ:gut | experiment:AB4 | group:Naive_plus ABX	endpoint.dpi=84; delta_weight=26.97; liver_weight=3.188; spleen_weight=0.073; liver_load=-; spleen_load=-; RAW_FILE_NAME=1686_Naive_plus_ABX_gut_P79.raw
SUBJECT_SAMPLE_FACTORS           	1686	X1686_Naive_plus_ABX_liver_P79.mzXML	organ:liver | experiment:AB4 | group:Naive_plus ABX	endpoint.dpi=84; delta_weight=26.97; liver_weight=3.188; spleen_weight=0.073; liver_load=-; spleen_load=-; RAW_FILE_NAME=1686_Naive_plus_ABX_liver_P79.raw
SUBJECT_SAMPLE_FACTORS           	1686	X1686_Naive_plus_ABX_spleen_P79_1.mzXML	organ:spleen | experiment:AB4 | group:Naive_plus ABX	endpoint.dpi=84; delta_weight=26.97; liver_weight=3.188; spleen_weight=0.073; liver_load=-; spleen_load=-; RAW_FILE_NAME=1686_Naive_plus_ABX_spleen_P79_1.raw
SUBJECT_SAMPLE_FACTORS           	1686	X1686_Naive_plus_ABX_spleen_P79_2.mzXML	organ:spleen | experiment:AB4 | group:Naive_plus ABX	endpoint.dpi=84; delta_weight=26.97; liver_weight=3.188; spleen_weight=0.073; liver_load=-; spleen_load=-; RAW_FILE_NAME=1686_Naive_plus_ABX_spleen_P79_2.raw
SUBJECT_SAMPLE_FACTORS           	1687	X1687_Naive_plus_ABX_gut_P79.mzXML	organ:gut | experiment:AB4 | group:Naive_plus ABX	endpoint.dpi=84; delta_weight=45.45; liver_weight=3.718; spleen_weight=0.088; liver_load=-; spleen_load=-; RAW_FILE_NAME=1687_Naive_plus_ABX_gut_P79.raw
SUBJECT_SAMPLE_FACTORS           	1687	X1687_Naive_plus_ABX_liver_P79.mzXML	organ:liver | experiment:AB4 | group:Naive_plus ABX	endpoint.dpi=84; delta_weight=45.45; liver_weight=3.718; spleen_weight=0.088; liver_load=-; spleen_load=-; RAW_FILE_NAME=1687_Naive_plus_ABX_liver_P79.raw
SUBJECT_SAMPLE_FACTORS           	1687	X1687_Naive_plus_ABX_spleen_P79_1.mzXML	organ:spleen | experiment:AB4 | group:Naive_plus ABX	endpoint.dpi=84; delta_weight=45.45; liver_weight=3.718; spleen_weight=0.088; liver_load=-; spleen_load=-; RAW_FILE_NAME=1687_Naive_plus_ABX_spleen_P79_1.raw
SUBJECT_SAMPLE_FACTORS           	1687	X1687_Naive_plus_ABX_spleen_P79_2.mzXML	organ:spleen | experiment:AB4 | group:Naive_plus ABX	endpoint.dpi=84; delta_weight=45.45; liver_weight=3.718; spleen_weight=0.088; liver_load=-; spleen_load=-; RAW_FILE_NAME=1687_Naive_plus_ABX_spleen_P79_2.raw
SUBJECT_SAMPLE_FACTORS           	1688	X1688_Naive_gut_P79.mzXML	organ:gut | experiment:AB4 | group:Naive	endpoint.dpi=84; delta_weight=30.77; liver_weight=4.692; spleen_weight=0.1097; liver_load=-; spleen_load=-; RAW_FILE_NAME=1688_Naive_gut_P79.raw
SUBJECT_SAMPLE_FACTORS           	1688	X1688_Naive_liver_P79.mzXML	organ:liver | experiment:AB4 | group:Naive	endpoint.dpi=84; delta_weight=30.77; liver_weight=4.692; spleen_weight=0.1097; liver_load=-; spleen_load=-; RAW_FILE_NAME=1688_Naive_liver_P79.raw
SUBJECT_SAMPLE_FACTORS           	1688	X1688_Naive_spleen_P79_1.mzXML	organ:spleen | experiment:AB4 | group:Naive	endpoint.dpi=84; delta_weight=30.77; liver_weight=4.692; spleen_weight=0.1097; liver_load=-; spleen_load=-; RAW_FILE_NAME=1688_Naive_spleen_P79_1.raw
SUBJECT_SAMPLE_FACTORS           	1688	X1688_Naive_spleen_P79_2.mzXML	organ:spleen | experiment:AB4 | group:Naive	endpoint.dpi=84; delta_weight=30.77; liver_weight=4.692; spleen_weight=0.1097; liver_load=-; spleen_load=-; RAW_FILE_NAME=1688_Naive_spleen_P79_2.raw
SUBJECT_SAMPLE_FACTORS           	1689	X1689_Naive_gut_P79.mzXML	organ:gut | experiment:AB4 | group:Naive	endpoint.dpi=84; delta_weight=32.03; liver_weight=5.708; spleen_weight=0.11; liver_load=-; spleen_load=-; RAW_FILE_NAME=1689_Naive_gut_P79.raw
SUBJECT_SAMPLE_FACTORS           	1689	X1689_Naive_liver_P79.mzXML	organ:liver | experiment:AB4 | group:Naive	endpoint.dpi=84; delta_weight=32.03; liver_weight=5.708; spleen_weight=0.11; liver_load=-; spleen_load=-; RAW_FILE_NAME=1689_Naive_liver_P79.raw
SUBJECT_SAMPLE_FACTORS           	1689	X1689_Naive_spleen_P79_1.mzXML	organ:spleen | experiment:AB4 | group:Naive	endpoint.dpi=84; delta_weight=32.03; liver_weight=5.708; spleen_weight=0.11; liver_load=-; spleen_load=-; RAW_FILE_NAME=1689_Naive_spleen_P79_1.raw
SUBJECT_SAMPLE_FACTORS           	1689	X1689_Naive_spleen_P79_2.mzXML	organ:spleen | experiment:AB4 | group:Naive	endpoint.dpi=84; delta_weight=32.03; liver_weight=5.708; spleen_weight=0.11; liver_load=-; spleen_load=-; RAW_FILE_NAME=1689_Naive_spleen_P79_2.raw
SUBJECT_SAMPLE_FACTORS           	1690	X1690_Ld1s_plus_ABX_gut_P79.mzXML	organ:gut | experiment:AB4 | group:Ld1s_plus ABX	endpoint.dpi=85; delta_weight=16.67; liver_weight=5.733; spleen_weight=0.749; liver_load=2.32E+09; spleen_load=3.71E+10; RAW_FILE_NAME=1690_Ld1s_plus_ABX_gut_P79.raw
SUBJECT_SAMPLE_FACTORS           	1690	X1690_Ld1s_plus_ABX_liver_P79.mzXML	organ:liver | experiment:AB4 | group:Ld1s_plus ABX	endpoint.dpi=85; delta_weight=16.67; liver_weight=5.733; spleen_weight=0.749; liver_load=2.32E+09; spleen_load=3.71E+10; RAW_FILE_NAME=1690_Ld1s_plus_ABX_liver_P79.raw
SUBJECT_SAMPLE_FACTORS           	1690	X1690_Ld1s_plus_ABX_spleen_P79_1.mzXML	organ:spleen | experiment:AB4 | group:Ld1s_plus ABX	endpoint.dpi=85; delta_weight=16.67; liver_weight=5.733; spleen_weight=0.749; liver_load=2.32E+09; spleen_load=3.71E+10; RAW_FILE_NAME=1690_Ld1s_plus_ABX_spleen_P79_1.raw
SUBJECT_SAMPLE_FACTORS           	1690	X1690_Ld1s_plus_ABX_spleen_P79_2.mzXML	organ:spleen | experiment:AB4 | group:Ld1s_plus ABX	endpoint.dpi=85; delta_weight=16.67; liver_weight=5.733; spleen_weight=0.749; liver_load=2.32E+09; spleen_load=3.71E+10; RAW_FILE_NAME=1690_Ld1s_plus_ABX_spleen_P79_2.raw
SUBJECT_SAMPLE_FACTORS           	1691	X1691_Ld1s_plus_ABX_gut_P79.mzXML	organ:gut | experiment:AB4 | group:Ld1s_plus ABX	endpoint.dpi=85; delta_weight=-7.92; liver_weight=4.949; spleen_weight=0.507; liver_load=1.89E+10; spleen_load=2.77E+10; RAW_FILE_NAME=1691_Ld1s_plus_ABX_gut_P79.raw
SUBJECT_SAMPLE_FACTORS           	1691	X1691_Ld1s_plus_ABX_liver_P79.mzXML	organ:liver | experiment:AB4 | group:Ld1s_plus ABX	endpoint.dpi=85; delta_weight=-7.92; liver_weight=4.949; spleen_weight=0.507; liver_load=1.89E+10; spleen_load=2.77E+10; RAW_FILE_NAME=1691_Ld1s_plus_ABX_liver_P79.raw
SUBJECT_SAMPLE_FACTORS           	1691	X1691_Ld1s_plus_ABX_spleen_P79_1.mzXML	organ:spleen | experiment:AB4 | group:Ld1s_plus ABX	endpoint.dpi=85; delta_weight=-7.92; liver_weight=4.949; spleen_weight=0.507; liver_load=1.89E+10; spleen_load=2.77E+10; RAW_FILE_NAME=1691_Ld1s_plus_ABX_spleen_P79_1.raw
SUBJECT_SAMPLE_FACTORS           	1691	X1691_Ld1s_plus_ABX_spleen_P79_2.mzXML	organ:spleen | experiment:AB4 | group:Ld1s_plus ABX	endpoint.dpi=85; delta_weight=-7.92; liver_weight=4.949; spleen_weight=0.507; liver_load=1.89E+10; spleen_load=2.77E+10; RAW_FILE_NAME=1691_Ld1s_plus_ABX_spleen_P79_2.raw
SUBJECT_SAMPLE_FACTORS           	1692	X1692_Ld1s_gut_P79.mzXML	organ:gut | experiment:AB4 | group:Ld1s	endpoint.dpi=85; delta_weight=23.08; liver_weight=7.865; spleen_weight=1.005; liver_load=6.13E+08; spleen_load=3.79E+09; RAW_FILE_NAME=1692_Ld1s_gut_P79.raw
SUBJECT_SAMPLE_FACTORS           	1692	X1692_Ld1s_liver_P79.mzXML	organ:liver | experiment:AB4 | group:Ld1s	endpoint.dpi=85; delta_weight=23.08; liver_weight=7.865; spleen_weight=1.005; liver_load=6.13E+08; spleen_load=3.79E+09; RAW_FILE_NAME=1692_Ld1s_liver_P79.raw
SUBJECT_SAMPLE_FACTORS           	1692	X1692_Ld1s_spleen_P79_1.mzXML	organ:spleen | experiment:AB4 | group:Ld1s	endpoint.dpi=85; delta_weight=23.08; liver_weight=7.865; spleen_weight=1.005; liver_load=6.13E+08; spleen_load=3.79E+09; RAW_FILE_NAME=1692_Ld1s_spleen_P79_1.raw
SUBJECT_SAMPLE_FACTORS           	1692	X1692_Ld1s_spleen_P79_2.mzXML	organ:spleen | experiment:AB4 | group:Ld1s	endpoint.dpi=85; delta_weight=23.08; liver_weight=7.865; spleen_weight=1.005; liver_load=6.13E+08; spleen_load=3.79E+09; RAW_FILE_NAME=1692_Ld1s_spleen_P79_2.raw
SUBJECT_SAMPLE_FACTORS           	1693	X1693_Ld1s_gut_P79.mzXML	organ:gut | experiment:AB4 | group:Ld1s	endpoint.dpi=85; delta_weight=-17.74; liver_weight=5.752; spleen_weight=0.767; liver_load=1.24E+10; spleen_load=1.72E+10; RAW_FILE_NAME=1693_Ld1s_gut_P79.raw
SUBJECT_SAMPLE_FACTORS           	1693	X1693_Ld1s_liver_P79.mzXML	organ:liver | experiment:AB4 | group:Ld1s	endpoint.dpi=85; delta_weight=-17.74; liver_weight=5.752; spleen_weight=0.767; liver_load=1.24E+10; spleen_load=1.72E+10; RAW_FILE_NAME=1693_Ld1s_liver_P79.raw
SUBJECT_SAMPLE_FACTORS           	1693	X1693_Ld1s_spleen_P79_1.mzXML	organ:spleen | experiment:AB4 | group:Ld1s	endpoint.dpi=85; delta_weight=-17.74; liver_weight=5.752; spleen_weight=0.767; liver_load=1.24E+10; spleen_load=1.72E+10; RAW_FILE_NAME=1693_Ld1s_spleen_P79_1.raw
SUBJECT_SAMPLE_FACTORS           	1693	X1693_Ld1s_spleen_P79_2.mzXML	organ:spleen | experiment:AB4 | group:Ld1s	endpoint.dpi=85; delta_weight=-17.74; liver_weight=5.752; spleen_weight=0.767; liver_load=1.24E+10; spleen_load=1.72E+10; RAW_FILE_NAME=1693_Ld1s_spleen_P79_2.raw
SUBJECT_SAMPLE_FACTORS           	1694	X1694_Ld1s_gut_P79.mzXML	organ:gut | experiment:AB4 | group:Ld1s	endpoint.dpi=85; delta_weight=4; liver_weight=6.58; spleen_weight=0.896; liver_load=7.42E+08; spleen_load=9.83E+08; RAW_FILE_NAME=1694_Ld1s_gut_P79.raw
SUBJECT_SAMPLE_FACTORS           	1694	X1694_Ld1s_liver_P79.mzXML	organ:liver | experiment:AB4 | group:Ld1s	endpoint.dpi=85; delta_weight=4; liver_weight=6.58; spleen_weight=0.896; liver_load=7.42E+08; spleen_load=9.83E+08; RAW_FILE_NAME=1694_Ld1s_liver_P79.raw
SUBJECT_SAMPLE_FACTORS           	1694	X1694_Ld1s_spleen_P79_1.mzXML	organ:spleen | experiment:AB4 | group:Ld1s	endpoint.dpi=85; delta_weight=4; liver_weight=6.58; spleen_weight=0.896; liver_load=7.42E+08; spleen_load=9.83E+08; RAW_FILE_NAME=1694_Ld1s_spleen_P79_1.raw
SUBJECT_SAMPLE_FACTORS           	1694	X1694_Ld1s_spleen_P79_2.mzXML	organ:spleen | experiment:AB4 | group:Ld1s	endpoint.dpi=85; delta_weight=4; liver_weight=6.58; spleen_weight=0.896; liver_load=7.42E+08; spleen_load=9.83E+08; RAW_FILE_NAME=1694_Ld1s_spleen_P79_2.raw
SUBJECT_SAMPLE_FACTORS           	1695	X1695_Ld1s_gut_P79.mzXML	organ:gut | experiment:AB4 | group:Ld1s	endpoint.dpi=85; delta_weight=-5.51; liver_weight=7.136; spleen_weight=1.025; liver_load=6.03E+08; spleen_load=2.33E+09; RAW_FILE_NAME=1695_Ld1s_gut_P79.raw
SUBJECT_SAMPLE_FACTORS           	1695	X1695_Ld1s_liver_P79.mzXML	organ:liver | experiment:AB4 | group:Ld1s	endpoint.dpi=85; delta_weight=-5.51; liver_weight=7.136; spleen_weight=1.025; liver_load=6.03E+08; spleen_load=2.33E+09; RAW_FILE_NAME=1695_Ld1s_liver_P79.raw
SUBJECT_SAMPLE_FACTORS           	1695	X1695_Ld1s_spleen_P79_1.mzXML	organ:spleen | experiment:AB4 | group:Ld1s	endpoint.dpi=85; delta_weight=-5.51; liver_weight=7.136; spleen_weight=1.025; liver_load=6.03E+08; spleen_load=2.33E+09; RAW_FILE_NAME=1695_Ld1s_spleen_P79_1.raw
SUBJECT_SAMPLE_FACTORS           	1696	X1696_Ld1s_plus_ABX_gut_P79.mzXML	organ:gut | experiment:AB4 | group:Ld1s_plus ABX	endpoint.dpi=86; delta_weight=6.06; liver_weight=5.178; spleen_weight=0.6; liver_load=3.10E+08; spleen_load=1.01E+09; RAW_FILE_NAME=1696_Ld1s_plus_ABX_gut_P79.raw
SUBJECT_SAMPLE_FACTORS           	1696	X1696_Ld1s_plus_ABX_liver_P79.mzXML	organ:liver | experiment:AB4 | group:Ld1s_plus ABX	endpoint.dpi=86; delta_weight=6.06; liver_weight=5.178; spleen_weight=0.6; liver_load=3.10E+08; spleen_load=1.01E+09; RAW_FILE_NAME=1696_Ld1s_plus_ABX_liver_P79.raw
SUBJECT_SAMPLE_FACTORS           	1696	X1696_Ld1s_plus_ABX_spleen_P79_1.mzXML	organ:spleen | experiment:AB4 | group:Ld1s_plus ABX	endpoint.dpi=86; delta_weight=6.06; liver_weight=5.178; spleen_weight=0.6; liver_load=3.10E+08; spleen_load=1.01E+09; RAW_FILE_NAME=1696_Ld1s_plus_ABX_spleen_P79_1.raw
SUBJECT_SAMPLE_FACTORS           	1696	X1696_Ld1s_plus_ABX_spleen_P79_2.mzXML	organ:spleen | experiment:AB4 | group:Ld1s_plus ABX	endpoint.dpi=86; delta_weight=6.06; liver_weight=5.178; spleen_weight=0.6; liver_load=3.10E+08; spleen_load=1.01E+09; RAW_FILE_NAME=1696_Ld1s_plus_ABX_spleen_P79_2.raw
SUBJECT_SAMPLE_FACTORS           	1697	X1697_Ld1s_plus_ABX_gut_P79.mzXML	organ:gut | experiment:AB4 | group:Ld1s_plus ABX	endpoint.dpi=86; delta_weight=1.09; liver_weight=4.406; spleen_weight=0.626; liver_load=2.87E+08; spleen_load=2.28E+09; RAW_FILE_NAME=1697_Ld1s_plus_ABX_gut_P79.raw
SUBJECT_SAMPLE_FACTORS           	1697	X1697_Ld1s_plus_ABX_liver_P79.mzXML	organ:liver | experiment:AB4 | group:Ld1s_plus ABX	endpoint.dpi=86; delta_weight=1.09; liver_weight=4.406; spleen_weight=0.626; liver_load=2.87E+08; spleen_load=2.28E+09; RAW_FILE_NAME=1697_Ld1s_plus_ABX_liver_P79.raw
SUBJECT_SAMPLE_FACTORS           	1697	X1697_Ld1s_plus_ABX_spleen_P79_1.mzXML	organ:spleen | experiment:AB4 | group:Ld1s_plus ABX	endpoint.dpi=86; delta_weight=1.09; liver_weight=4.406; spleen_weight=0.626; liver_load=2.87E+08; spleen_load=2.28E+09; RAW_FILE_NAME=1697_Ld1s_plus_ABX_spleen_P79_1.raw
SUBJECT_SAMPLE_FACTORS           	1697	X1697_Ld1s_plus_ABX_spleen_P79_2.mzXML	organ:spleen | experiment:AB4 | group:Ld1s_plus ABX	endpoint.dpi=86; delta_weight=1.09; liver_weight=4.406; spleen_weight=0.626; liver_load=2.87E+08; spleen_load=2.28E+09; RAW_FILE_NAME=1697_Ld1s_plus_ABX_spleen_P79_2.raw
SUBJECT_SAMPLE_FACTORS           	1698	X1698_Ld1s_gut_P79.mzXML	organ:gut | experiment:AB4 | group:Ld1s	endpoint.dpi=87; delta_weight=22.22; liver_weight=8.96; spleen_weight=1.007; liver_load=7.13E+07; spleen_load=1.13E+09; RAW_FILE_NAME=1698_Ld1s_gut_P79.raw
SUBJECT_SAMPLE_FACTORS           	1698	X1698_Ld1s_liver_P79.mzXML	organ:liver | experiment:AB4 | group:Ld1s	endpoint.dpi=87; delta_weight=22.22; liver_weight=8.96; spleen_weight=1.007; liver_load=7.13E+07; spleen_load=1.13E+09; RAW_FILE_NAME=1698_Ld1s_liver_P79.raw
SUBJECT_SAMPLE_FACTORS           	1698	X1698_Ld1s_spleen_P79_1.mzXML	organ:spleen | experiment:AB4 | group:Ld1s	endpoint.dpi=87; delta_weight=22.22; liver_weight=8.96; spleen_weight=1.007; liver_load=7.13E+07; spleen_load=1.13E+09; RAW_FILE_NAME=1698_Ld1s_spleen_P79_1.raw
SUBJECT_SAMPLE_FACTORS           	1698	X1698_Ld1s_spleen_P79_2.mzXML	organ:spleen | experiment:AB4 | group:Ld1s	endpoint.dpi=87; delta_weight=22.22; liver_weight=8.96; spleen_weight=1.007; liver_load=7.13E+07; spleen_load=1.13E+09; RAW_FILE_NAME=1698_Ld1s_spleen_P79_2.raw
SUBJECT_SAMPLE_FACTORS           	1699	X1699_Ld1s_gut_P79.mzXML	organ:gut | experiment:AB4 | group:Ld1s	endpoint.dpi=87; delta_weight=-4.92; liver_weight=6.527; spleen_weight=0.762; liver_load=2.09E+08; spleen_load=5.69E+08; RAW_FILE_NAME=1699_Ld1s_gut_P79.raw
SUBJECT_SAMPLE_FACTORS           	1699	X1699_Ld1s_liver_P79.mzXML	organ:liver | experiment:AB4 | group:Ld1s	endpoint.dpi=87; delta_weight=-4.92; liver_weight=6.527; spleen_weight=0.762; liver_load=2.09E+08; spleen_load=5.69E+08; RAW_FILE_NAME=1699_Ld1s_liver_P79.raw
SUBJECT_SAMPLE_FACTORS           	1699	X1699_Ld1s_spleen_P79_1.mzXML	organ:spleen | experiment:AB4 | group:Ld1s	endpoint.dpi=87; delta_weight=-4.92; liver_weight=6.527; spleen_weight=0.762; liver_load=2.09E+08; spleen_load=5.69E+08; RAW_FILE_NAME=1699_Ld1s_spleen_P79_1.raw
SUBJECT_SAMPLE_FACTORS           	1699	X1699_Ld1s_spleen_P79_2.mzXML	organ:spleen | experiment:AB4 | group:Ld1s	endpoint.dpi=87; delta_weight=-4.92; liver_weight=6.527; spleen_weight=0.762; liver_load=2.09E+08; spleen_load=5.69E+08; RAW_FILE_NAME=1699_Ld1s_spleen_P79_2.raw
SUBJECT_SAMPLE_FACTORS           	1701	X1701_Naive_gut_P79.mzXML	organ:gut | experiment:AB5 | group:Naive	endpoint.dpi=92; delta_weight=0; liver_weight=4.57; spleen_weight=0.116; liver_load=-; spleen_load=-; RAW_FILE_NAME=1701_Naive_gut_P79.raw
SUBJECT_SAMPLE_FACTORS           	1701	X1701_Naive_liver_P79.mzXML	organ:liver | experiment:AB5 | group:Naive	endpoint.dpi=92; delta_weight=0; liver_weight=4.57; spleen_weight=0.116; liver_load=-; spleen_load=-; RAW_FILE_NAME=1701_Naive_liver_P79.raw
SUBJECT_SAMPLE_FACTORS           	1701	X1701_Naive_spleen_P79_1.mzXML	organ:spleen | experiment:AB5 | group:Naive	endpoint.dpi=92; delta_weight=0; liver_weight=4.57; spleen_weight=0.116; liver_load=-; spleen_load=-; RAW_FILE_NAME=1701_Naive_spleen_P79_1.raw
SUBJECT_SAMPLE_FACTORS           	1701	X1701_Naive_spleen_P79_2.mzXML	organ:spleen | experiment:AB5 | group:Naive	endpoint.dpi=92; delta_weight=0; liver_weight=4.57; spleen_weight=0.116; liver_load=-; spleen_load=-; RAW_FILE_NAME=1701_Naive_spleen_P79_2.raw
SUBJECT_SAMPLE_FACTORS           	1702	X1702_Naive_gut_P79.mzXML	organ:gut | experiment:AB5 | group:Naive	endpoint.dpi=92; delta_weight=19.8; liver_weight=4.803; spleen_weight=0.131; liver_load=-; spleen_load=-; RAW_FILE_NAME=1702_Naive_gut_P79.raw
SUBJECT_SAMPLE_FACTORS           	1702	X1702_Naive_liver_P79.mzXML	organ:liver | experiment:AB5 | group:Naive	endpoint.dpi=92; delta_weight=19.8; liver_weight=4.803; spleen_weight=0.131; liver_load=-; spleen_load=-; RAW_FILE_NAME=1702_Naive_liver_P79.raw
SUBJECT_SAMPLE_FACTORS           	1702	X1702_Naive_spleen_P79_1.mzXML	organ:spleen | experiment:AB5 | group:Naive	endpoint.dpi=92; delta_weight=19.8; liver_weight=4.803; spleen_weight=0.131; liver_load=-; spleen_load=-; RAW_FILE_NAME=1702_Naive_spleen_P79_1.raw
SUBJECT_SAMPLE_FACTORS           	1702	X1702_Naive_spleen_P79_2.mzXML	organ:spleen | experiment:AB5 | group:Naive	endpoint.dpi=92; delta_weight=19.8; liver_weight=4.803; spleen_weight=0.131; liver_load=-; spleen_load=-; RAW_FILE_NAME=1702_Naive_spleen_P79_2.raw
SUBJECT_SAMPLE_FACTORS           	1703	X1703_Ld1s_gut_P79.mzXML	organ:gut | experiment:AB5 | group:Ld1s	endpoint.dpi=92; delta_weight=2.2; liver_weight=6.51; spleen_weight=0.808; liver_load=3.83E+08; spleen_load=3.40E+08; RAW_FILE_NAME=1703_Ld1s_gut_P79.raw
SUBJECT_SAMPLE_FACTORS           	1703	X1703_Ld1s_liver_P79.mzXML	organ:liver | experiment:AB5 | group:Ld1s	endpoint.dpi=92; delta_weight=2.2; liver_weight=6.51; spleen_weight=0.808; liver_load=3.83E+08; spleen_load=3.40E+08; RAW_FILE_NAME=1703_Ld1s_liver_P79.raw
SUBJECT_SAMPLE_FACTORS           	1703	X1703_Ld1s_spleen_P79_1.mzXML	organ:spleen | experiment:AB5 | group:Ld1s	endpoint.dpi=92; delta_weight=2.2; liver_weight=6.51; spleen_weight=0.808; liver_load=3.83E+08; spleen_load=3.40E+08; RAW_FILE_NAME=1703_Ld1s_spleen_P79_1.raw
SUBJECT_SAMPLE_FACTORS           	1703	X1703_Ld1s_spleen_P79_2.mzXML	organ:spleen | experiment:AB5 | group:Ld1s	endpoint.dpi=92; delta_weight=2.2; liver_weight=6.51; spleen_weight=0.808; liver_load=3.83E+08; spleen_load=3.40E+08; RAW_FILE_NAME=1703_Ld1s_spleen_P79_2.raw
SUBJECT_SAMPLE_FACTORS           	1704	X1704_Ld1s_plus_ABX_gut_P79.mzXML	organ:gut | experiment:AB5 | group:Ld1s_plus ABX	endpoint.dpi=92; delta_weight=5.3; liver_weight=7.84; spleen_weight=0.817; liver_load=1.63E+08; spleen_load=8.92E+08; RAW_FILE_NAME=1704_Ld1s_plus_ABX_gut_P79.raw
SUBJECT_SAMPLE_FACTORS           	1704	X1704_Ld1s_plus_ABX_liver_P79.mzXML	organ:liver | experiment:AB5 | group:Ld1s_plus ABX	endpoint.dpi=92; delta_weight=5.3; liver_weight=7.84; spleen_weight=0.817; liver_load=1.63E+08; spleen_load=8.92E+08; RAW_FILE_NAME=1704_Ld1s_plus_ABX_liver_P79.raw
SUBJECT_SAMPLE_FACTORS           	1704	X1704_Ld1s_plus_ABX_spleen_P79_1.mzXML	organ:spleen | experiment:AB5 | group:Ld1s_plus ABX	endpoint.dpi=92; delta_weight=5.3; liver_weight=7.84; spleen_weight=0.817; liver_load=1.63E+08; spleen_load=8.92E+08; RAW_FILE_NAME=1704_Ld1s_plus_ABX_spleen_P79_1.raw
SUBJECT_SAMPLE_FACTORS           	1704	X1704_Ld1s_plus_ABX_spleen_P79_2.mzXML	organ:spleen | experiment:AB5 | group:Ld1s_plus ABX	endpoint.dpi=92; delta_weight=5.3; liver_weight=7.84; spleen_weight=0.817; liver_load=1.63E+08; spleen_load=8.92E+08; RAW_FILE_NAME=1704_Ld1s_plus_ABX_spleen_P79_2.raw
SUBJECT_SAMPLE_FACTORS           	1705	X1705_Ld1s_gut_P79.mzXML	organ:gut | experiment:AB5 | group:Ld1s	endpoint.dpi=94; delta_weight=2.5; liver_weight=8.72; spleen_weight=1.113; liver_load=7.69E+07; spleen_load=5.14E+08; RAW_FILE_NAME=1705_Ld1s_gut_P79.raw
SUBJECT_SAMPLE_FACTORS           	1705	X1705_Ld1s_liver_P79.mzXML	organ:liver | experiment:AB5 | group:Ld1s	endpoint.dpi=94; delta_weight=2.5; liver_weight=8.72; spleen_weight=1.113; liver_load=7.69E+07; spleen_load=5.14E+08; RAW_FILE_NAME=1705_Ld1s_liver_P79.raw
SUBJECT_SAMPLE_FACTORS           	1705	X1705_Ld1s_spleen_P79_1.mzXML	organ:spleen | experiment:AB5 | group:Ld1s	endpoint.dpi=94; delta_weight=2.5; liver_weight=8.72; spleen_weight=1.113; liver_load=7.69E+07; spleen_load=5.14E+08; RAW_FILE_NAME=1705_Ld1s_spleen_P79_1.raw
SUBJECT_SAMPLE_FACTORS           	1705	X1705_Ld1s_spleen_P79_2.mzXML	organ:spleen | experiment:AB5 | group:Ld1s	endpoint.dpi=94; delta_weight=2.5; liver_weight=8.72; spleen_weight=1.113; liver_load=7.69E+07; spleen_load=5.14E+08; RAW_FILE_NAME=1705_Ld1s_spleen_P79_2.raw
SUBJECT_SAMPLE_FACTORS           	1706	X1706_Ld1s_plus_ABX_gut_P79.mzXML	organ:gut | experiment:AB5 | group:Ld1s_plus ABX	endpoint.dpi=94; delta_weight=-26.4; liver_weight=5.6; spleen_weight=0.467; liver_load=3.62E+08; spleen_load=4.92E+09; RAW_FILE_NAME=1706_Ld1s_plus_ABX_gut_P79.raw
SUBJECT_SAMPLE_FACTORS           	1706	X1706_Ld1s_plus_ABX_liver_P79.mzXML	organ:liver | experiment:AB5 | group:Ld1s_plus ABX	endpoint.dpi=94; delta_weight=-26.4; liver_weight=5.6; spleen_weight=0.467; liver_load=3.62E+08; spleen_load=4.92E+09; RAW_FILE_NAME=1706_Ld1s_plus_ABX_liver_P79.raw
SUBJECT_SAMPLE_FACTORS           	1706	X1706_Ld1s_plus_ABX_spleen_P79_1.mzXML	organ:spleen | experiment:AB5 | group:Ld1s_plus ABX	endpoint.dpi=94; delta_weight=-26.4; liver_weight=5.6; spleen_weight=0.467; liver_load=3.62E+08; spleen_load=4.92E+09; RAW_FILE_NAME=1706_Ld1s_plus_ABX_spleen_P79_1.raw
SUBJECT_SAMPLE_FACTORS           	1706	X1706_Ld1s_plus_ABX_spleen_P79_2.mzXML	organ:spleen | experiment:AB5 | group:Ld1s_plus ABX	endpoint.dpi=94; delta_weight=-26.4; liver_weight=5.6; spleen_weight=0.467; liver_load=3.62E+08; spleen_load=4.92E+09; RAW_FILE_NAME=1706_Ld1s_plus_ABX_spleen_P79_2.raw
SUBJECT_SAMPLE_FACTORS           	1707	X1707_Naive_plus_ABX_liver_P79.mzXML	organ:liver | experiment:AB5 | group:Naive_plus ABX	endpoint.dpi=94; delta_weight=26.72; liver_weight=5.26; spleen_weight=0.131; liver_load=-; spleen_load=-; RAW_FILE_NAME=1707_Naive_plus_ABX_liver_P79.raw
SUBJECT_SAMPLE_FACTORS           	1707	X1707_Naive_plus_ABX_spleen_P79_1.mzXML	organ:spleen | experiment:AB5 | group:Naive_plus ABX	endpoint.dpi=94; delta_weight=26.72; liver_weight=5.26; spleen_weight=0.131; liver_load=-; spleen_load=-; RAW_FILE_NAME=1707_Naive_plus_ABX_spleen_P79_1.raw
SUBJECT_SAMPLE_FACTORS           	1707	X1707_Naive_plus_ABX_spleen_P79_2.mzXML	organ:spleen | experiment:AB5 | group:Naive_plus ABX	endpoint.dpi=94; delta_weight=26.72; liver_weight=5.26; spleen_weight=0.131; liver_load=-; spleen_load=-; RAW_FILE_NAME=1707_Naive_plus_ABX_spleen_P79_2.raw
SUBJECT_SAMPLE_FACTORS           	1708	X1708_Naive_plus_ABX_gut_P79.mzXML	organ:gut | experiment:AB5 | group:Naive_plus ABX	endpoint.dpi=94; delta_weight=28.9; liver_weight=4.55; spleen_weight=0.1; liver_load=-; spleen_load=-; RAW_FILE_NAME=1708_Naive_plus_ABX_gut_P79.raw
SUBJECT_SAMPLE_FACTORS           	1708	X1708_Naive_plus_ABX_liver_P79.mzXML	organ:liver | experiment:AB5 | group:Naive_plus ABX	endpoint.dpi=94; delta_weight=28.9; liver_weight=4.55; spleen_weight=0.1; liver_load=-; spleen_load=-; RAW_FILE_NAME=1708_Naive_plus_ABX_liver_P79.raw
SUBJECT_SAMPLE_FACTORS           	1708	X1708_Naive_plus_ABX_spleen_P79_1.mzXML	organ:spleen | experiment:AB5 | group:Naive_plus ABX	endpoint.dpi=94; delta_weight=28.9; liver_weight=4.55; spleen_weight=0.1; liver_load=-; spleen_load=-; RAW_FILE_NAME=1708_Naive_plus_ABX_spleen_P79_1.raw
SUBJECT_SAMPLE_FACTORS           	1708	X1708_Naive_plus_ABX_spleen_P79_2.mzXML	organ:spleen | experiment:AB5 | group:Naive_plus ABX	endpoint.dpi=94; delta_weight=28.9; liver_weight=4.55; spleen_weight=0.1; liver_load=-; spleen_load=-; RAW_FILE_NAME=1708_Naive_plus_ABX_spleen_P79_2.raw
SUBJECT_SAMPLE_FACTORS           	1709	X1709_Ld1s_plus_ABX_gut_P80.mzXML	organ:gut | experiment:AB5 | group:Ld1s_plus ABX	endpoint.dpi=93; delta_weight=6.7; liver_weight=5.76; spleen_weight=0.936; liver_load=5.32E+08; spleen_load=1.32E+09; RAW_FILE_NAME=1709_Ld1s_plus_ABX_gut_P80.raw
SUBJECT_SAMPLE_FACTORS           	1709	X1709_Ld1s_plus_ABX_liver_P80.mzXML	organ:liver | experiment:AB5 | group:Ld1s_plus ABX	endpoint.dpi=93; delta_weight=6.7; liver_weight=5.76; spleen_weight=0.936; liver_load=5.32E+08; spleen_load=1.32E+09; RAW_FILE_NAME=1709_Ld1s_plus_ABX_liver_P80.raw
SUBJECT_SAMPLE_FACTORS           	1709	X1709_Ld1s_plus_ABX_spleen_P79_1.mzXML	organ:spleen | experiment:AB5 | group:Ld1s_plus ABX	endpoint.dpi=93; delta_weight=6.7; liver_weight=5.76; spleen_weight=0.936; liver_load=5.32E+08; spleen_load=1.32E+09; RAW_FILE_NAME=1709_Ld1s_plus_ABX_spleen_P79_1.raw
SUBJECT_SAMPLE_FACTORS           	1709	X1709_Ld1s_plus_ABX_spleen_P80_2.mzXML	organ:spleen | experiment:AB5 | group:Ld1s_plus ABX	endpoint.dpi=93; delta_weight=6.7; liver_weight=5.76; spleen_weight=0.936; liver_load=5.32E+08; spleen_load=1.32E+09; RAW_FILE_NAME=1709_Ld1s_plus_ABX_spleen_P80_2.raw
SUBJECT_SAMPLE_FACTORS           	1710	X1710_Ld1s_plus_ABX_gut_P80.mzXML	organ:gut | experiment:AB5 | group:Ld1s_plus ABX	endpoint.dpi=93; delta_weight=17; liver_weight=6.98; spleen_weight=1.144; liver_load=9.98E+07; spleen_load=7.21E+08; RAW_FILE_NAME=1710_Ld1s_plus_ABX_gut_P80.raw
SUBJECT_SAMPLE_FACTORS           	1710	X1710_Ld1s_plus_ABX_liver_P80.mzXML	organ:liver | experiment:AB5 | group:Ld1s_plus ABX	endpoint.dpi=93; delta_weight=17; liver_weight=6.98; spleen_weight=1.144; liver_load=9.98E+07; spleen_load=7.21E+08; RAW_FILE_NAME=1710_Ld1s_plus_ABX_liver_P80.raw
SUBJECT_SAMPLE_FACTORS           	1710	X1710_Ld1s_plus_ABX_spleen_P80_1.mzXML	organ:spleen | experiment:AB5 | group:Ld1s_plus ABX	endpoint.dpi=93; delta_weight=17; liver_weight=6.98; spleen_weight=1.144; liver_load=9.98E+07; spleen_load=7.21E+08; RAW_FILE_NAME=1710_Ld1s_plus_ABX_spleen_P80_1.raw
SUBJECT_SAMPLE_FACTORS           	1710	X1710_Ld1s_plus_ABX_spleen_P80_2.mzXML	organ:spleen | experiment:AB5 | group:Ld1s_plus ABX	endpoint.dpi=93; delta_weight=17; liver_weight=6.98; spleen_weight=1.144; liver_load=9.98E+07; spleen_load=7.21E+08; RAW_FILE_NAME=1710_Ld1s_plus_ABX_spleen_P80_2.raw
SUBJECT_SAMPLE_FACTORS           	1711	X1711_Ld1s_gut_P80.mzXML	organ:gut | experiment:AB5 | group:Ld1s	endpoint.dpi=93; delta_weight=-16.9; liver_weight=6.71; spleen_weight=0.892; liver_load=3.97E+07; spleen_load=2.49E+08; RAW_FILE_NAME=1711_Ld1s_gut_P80.raw
SUBJECT_SAMPLE_FACTORS           	1711	X1711_Ld1s_liver_P80.mzXML	organ:liver | experiment:AB5 | group:Ld1s	endpoint.dpi=93; delta_weight=-16.9; liver_weight=6.71; spleen_weight=0.892; liver_load=3.97E+07; spleen_load=2.49E+08; RAW_FILE_NAME=1711_Ld1s_liver_P80.raw
SUBJECT_SAMPLE_FACTORS           	1711	X1711_Ld1s_spleen_P80_1.mzXML	organ:spleen | experiment:AB5 | group:Ld1s	endpoint.dpi=93; delta_weight=-16.9; liver_weight=6.71; spleen_weight=0.892; liver_load=3.97E+07; spleen_load=2.49E+08; RAW_FILE_NAME=1711_Ld1s_spleen_P80_1.raw
SUBJECT_SAMPLE_FACTORS           	1711	X1711_Ld1s_spleen_P80_2.mzXML	organ:spleen | experiment:AB5 | group:Ld1s	endpoint.dpi=93; delta_weight=-16.9; liver_weight=6.71; spleen_weight=0.892; liver_load=3.97E+07; spleen_load=2.49E+08; RAW_FILE_NAME=1711_Ld1s_spleen_P80_2.raw
SUBJECT_SAMPLE_FACTORS           	1712	X1712_Ld1s_gut_P80.mzXML	organ:gut | experiment:AB5 | group:Ld1s	endpoint.dpi=93; delta_weight=-33.3; liver_weight=5.227; spleen_weight=0.755; liver_load=1.20E+08; spleen_load=9.42E+08; RAW_FILE_NAME=1712_Ld1s_gut_P80.raw
SUBJECT_SAMPLE_FACTORS           	1712	X1712_Ld1s_liver_P80.mzXML	organ:liver | experiment:AB5 | group:Ld1s	endpoint.dpi=93; delta_weight=-33.3; liver_weight=5.227; spleen_weight=0.755; liver_load=1.20E+08; spleen_load=9.42E+08; RAW_FILE_NAME=1712_Ld1s_liver_P80.raw
SUBJECT_SAMPLE_FACTORS           	1712	X1712_Ld1s_spleen_P80_1.mzXML	organ:spleen | experiment:AB5 | group:Ld1s	endpoint.dpi=93; delta_weight=-33.3; liver_weight=5.227; spleen_weight=0.755; liver_load=1.20E+08; spleen_load=9.42E+08; RAW_FILE_NAME=1712_Ld1s_spleen_P80_1.raw
SUBJECT_SAMPLE_FACTORS           	1712	X1712_Ld1s_spleen_P80_2.mzXML	organ:spleen | experiment:AB5 | group:Ld1s	endpoint.dpi=93; delta_weight=-33.3; liver_weight=5.227; spleen_weight=0.755; liver_load=1.20E+08; spleen_load=9.42E+08; RAW_FILE_NAME=1712_Ld1s_spleen_P80_2.raw
SUBJECT_SAMPLE_FACTORS           	6.mix	X6.mix.mzXML	organ:6.mix | experiment:6.mix | group:6.mix	endpoint.dpi=6.mix; delta_weight=6.mix; liver_weight=6.mix; spleen_weight=6.mix; liver_load=6.mix; spleen_load=6.mix; RAW_FILE_NAME=6.mix.raw
SUBJECT_SAMPLE_FACTORS           	6.mix	X6.mix_20200814130541.mzXML	organ:6.mix | experiment:6.mix | group:6.mix	endpoint.dpi=6.mix; delta_weight=6.mix; liver_weight=6.mix; spleen_weight=6.mix; liver_load=6.mix; spleen_load=6.mix; RAW_FILE_NAME=6.mix_20200814130541.raw
SUBJECT_SAMPLE_FACTORS           	6.mix	X6.mix_20200814164217.mzXML	organ:6.mix | experiment:6.mix | group:6.mix	endpoint.dpi=6.mix; delta_weight=6.mix; liver_weight=6.mix; spleen_weight=6.mix; liver_load=6.mix; spleen_load=6.mix; RAW_FILE_NAME=6.mix_20200814164217.raw
#COLLECTION
CO:COLLECTION_SUMMARY            	Organs were collected and stored at -80.
CO:SAMPLE_TYPE                   	Liver;Spleen;Gut
#TREATMENT
TR:TREATMENT_SUMMARY             	Hamsters were infected with Leishmania donovani or remained uninfected
#SAMPLEPREP
SP:SAMPLEPREP_SUMMARY            	Metabolites were extracted through a two-step extraction process, first in 50%
SP:SAMPLEPREP_SUMMARY            	methanol and then in 3:1 dichloromethane-methanol
#CHROMATOGRAPHY
CH:CHROMATOGRAPHY_TYPE           	Reversed phase
CH:INSTRUMENT_NAME               	Thermo Vanquish
CH:COLUMN_NAME                   	Phenomenex Kinetex C8 column (0.7 μm, 50 mm × 2.1 mm, 100 Å)
#ANALYSIS
AN:ANALYSIS_TYPE                 	MS
#MS
MS:INSTRUMENT_NAME               	Thermo Q Exactive Plus Orbitrap
MS:INSTRUMENT_TYPE               	Orbitrap
MS:MS_TYPE                       	ESI
MS:ION_MODE                      	POSITIVE
MS:MS_COMMENTS                   	-
MS:MS_RESULTS_FILE               	ST002347_AN003832_Results.txt	UNITS:peak area	Has m/z:Yes	Has RT:Yes	RT units:Minutes
#END