#METABOLOMICS WORKBENCH goldsteinlabucla_20230912_145022 DATATRACK_ID:4308 STUDY_ID:ST002864 ANALYSIS_ID:AN004696 PROJECT_ID:PR001786
VERSION             	1
CREATED_ON             	September 14, 2023, 10:19 am
#PROJECT
PR:PROJECT_TITLE                 	MYC is a regulator of androgen receptor inhibition-induced metabolic
PR:PROJECT_TITLE                 	requirements in prostate cancer
PR:PROJECT_SUMMARY               	Advanced prostate cancers are treated with therapies targeting the androgen
PR:PROJECT_SUMMARY               	receptor (AR) signaling pathway. While many tumors initially respond to AR
PR:PROJECT_SUMMARY               	inhibition, nearly all develop resistance. It is critical to understand how
PR:PROJECT_SUMMARY               	prostate tumor cells respond to AR inhibition in order to exploit
PR:PROJECT_SUMMARY               	therapy-induced phenotypes prior to the outgrowth of treatment-resistant
PR:PROJECT_SUMMARY               	disease. Here, we comprehensively characterize the effect of AR blockade on
PR:PROJECT_SUMMARY               	prostate cancer metabolism using transcriptomics, metabolomics and bioenergetics
PR:PROJECT_SUMMARY               	approaches. The metabolic response to AR inhibition is defined by reduced
PR:PROJECT_SUMMARY               	glycolysis, robust elongation of mitochondria, and increased reliance on
PR:PROJECT_SUMMARY               	mitochondrial oxidative metabolism. We establish DRP1 activity and MYC signaling
PR:PROJECT_SUMMARY               	as mediators of AR blockade-induced metabolic phenotypes. Rescuing DRP1
PR:PROJECT_SUMMARY               	phosphorylation after AR inhibition restores mitochondrial fission, while
PR:PROJECT_SUMMARY               	rescuing MYC restores glycolytic activity and prevents sensitivity to complex I
PR:PROJECT_SUMMARY               	inhibition. Our study provides new insight into the regulation of
PR:PROJECT_SUMMARY               	treatment-induced metabolic phenotypes and vulnerabilities in prostate cancer.
PR:INSTITUTE                     	University of California, Los Angeles
PR:DEPARTMENT                    	Molecular, Cell and Developmental Biology
PR:LABORATORY                    	Andrew Goldstein
PR:LAST_NAME                     	Goldstein
PR:FIRST_NAME                    	Andrew
PR:ADDRESS                       	610 Charles E Young Dr East, Goldstein Lab 3141 Terasaki Life Sci Bld, Los
PR:ADDRESS                       	Angeles, CA, 90095, USA
PR:EMAIL                         	AGoldstein@mednet.ucla.edu
PR:PHONE                         	3102061402
#STUDY
ST:STUDY_TITLE                   	Metabolic profiling, glucose tracing and glutamine tracing in naive and
ST:STUDY_TITLE                   	Enzalutamide-treated 16D prostate cancer cells expressing RFP or MYC
ST:STUDY_SUMMARY                 	Advanced prostate cancers are treated with therapies targeting the androgen
ST:STUDY_SUMMARY                 	receptor (AR) signaling pathway. While many tumors initially respond to AR
ST:STUDY_SUMMARY                 	inhibition, nearly all develop resistance. It is critical to understand how
ST:STUDY_SUMMARY                 	prostate tumor cells respond to AR inhibition in order to exploit
ST:STUDY_SUMMARY                 	therapy-induced phenotypes prior to the outgrowth of treatment-resistant
ST:STUDY_SUMMARY                 	disease. Here, we comprehensively characterize the effect of AR blockade on
ST:STUDY_SUMMARY                 	prostate cancer metabolism using transcriptomics, metabolomics and bioenergetics
ST:STUDY_SUMMARY                 	approaches. The metabolic response to AR inhibition is defined by reduced
ST:STUDY_SUMMARY                 	glycolysis, robust elongation of mitochondria, and increased reliance on
ST:STUDY_SUMMARY                 	mitochondrial oxidative metabolism. We establish DRP1 activity and MYC signaling
ST:STUDY_SUMMARY                 	as mediators of AR blockade-induced metabolic phenotypes. Rescuing DRP1
ST:STUDY_SUMMARY                 	phosphorylation after AR inhibition restores mitochondrial fission, while
ST:STUDY_SUMMARY                 	rescuing MYC restores glycolytic activity and prevents sensitivity to complex I
ST:STUDY_SUMMARY                 	inhibition. Our study provides new insight into the regulation of
ST:STUDY_SUMMARY                 	treatment-induced metabolic phenotypes and vulnerabilities in prostate cancer.
ST:INSTITUTE                     	University of California, Los Angeles
ST:DEPARTMENT                    	Molecular, Cell and Developmental Biology
ST:LABORATORY                    	Andrew Goldstein
ST:LAST_NAME                     	Goldstein
ST:FIRST_NAME                    	Andrew
ST:ADDRESS                       	610 Charles E Young Dr East, Goldstein Lab 3141 Terasaki Life Sci Bld, Los
ST:ADDRESS                       	Angeles, CA, 90095, USA
ST:EMAIL                         	AGoldstein@mednet.ucla.edu
ST:PHONE                         	3102061402
#SUBJECT
SU:SUBJECT_TYPE                  	Cultured cells
SU:SUBJECT_SPECIES               	Homo sapiens
SU:TAXONOMY_ID                   	9606
#SUBJECT_SAMPLE_FACTORS:         	SUBJECT(optional)[tab]SAMPLE[tab]FACTORS(NAME:VALUE pairs separated by |)[tab]Raw file names and additional sample data
SUBJECT_SAMPLE_FACTORS           	-	NN-001	Treatment:RFP_vehicle_C13Glc	RAW_FILE_NAME=NN-001.raw
SUBJECT_SAMPLE_FACTORS           	-	NN-002	Treatment:RFP_vehicle_C13Glc	RAW_FILE_NAME=NN-002.raw
SUBJECT_SAMPLE_FACTORS           	-	NN-003	Treatment:RFP_vehicle_C13Glc	RAW_FILE_NAME=NN-003.raw
SUBJECT_SAMPLE_FACTORS           	-	NN-004	Treatment:MYC_vehicle_C13Glc	RAW_FILE_NAME=NN-004.raw
SUBJECT_SAMPLE_FACTORS           	-	NN-005	Treatment:MYC_vehicle_C13Glc	RAW_FILE_NAME=NN-005.raw
SUBJECT_SAMPLE_FACTORS           	-	NN-006	Treatment:MYC_vehicle_C13Glc	RAW_FILE_NAME=NN-006.raw
SUBJECT_SAMPLE_FACTORS           	-	NN-007	Treatment:RFP_Enza_C13Glc	RAW_FILE_NAME=NN-007.raw
SUBJECT_SAMPLE_FACTORS           	-	NN-008	Treatment:RFP_Enza_C13Glc	RAW_FILE_NAME=NN-008.raw
SUBJECT_SAMPLE_FACTORS           	-	NN-009	Treatment:RFP_Enza_C13Glc	RAW_FILE_NAME=NN-009.raw
SUBJECT_SAMPLE_FACTORS           	-	NN-010	Treatment:MYC_Enza_C13Glc	RAW_FILE_NAME=NN-010.raw
SUBJECT_SAMPLE_FACTORS           	-	NN-011	Treatment:MYC_Enza_C13Glc	RAW_FILE_NAME=NN-011.raw
SUBJECT_SAMPLE_FACTORS           	-	NN-012	Treatment:MYC_Enza_C13Glc	RAW_FILE_NAME=NN-012.raw
SUBJECT_SAMPLE_FACTORS           	-	NN-013	Treatment:RFP_vehicle_C13Gln	RAW_FILE_NAME=NN-013.raw
SUBJECT_SAMPLE_FACTORS           	-	NN-014	Treatment:RFP_vehicle_C13Gln	RAW_FILE_NAME=NN-014.raw
SUBJECT_SAMPLE_FACTORS           	-	NN-015	Treatment:RFP_vehicle_C13Gln	RAW_FILE_NAME=NN-015.raw
SUBJECT_SAMPLE_FACTORS           	-	NN-016	Treatment:MYC_vehicle_C13Gln	RAW_FILE_NAME=NN-016.raw
SUBJECT_SAMPLE_FACTORS           	-	NN-017	Treatment:MYC_vehicle_C13Gln	RAW_FILE_NAME=NN-017.raw
SUBJECT_SAMPLE_FACTORS           	-	NN-018	Treatment:MYC_vehicle_C13Gln	RAW_FILE_NAME=NN-018.raw
SUBJECT_SAMPLE_FACTORS           	-	NN-019	Treatment:RFP_Enza_C13Gln	RAW_FILE_NAME=NN-019.raw
SUBJECT_SAMPLE_FACTORS           	-	NN-020	Treatment:RFP_Enza_C13Gln	RAW_FILE_NAME=NN-020.raw
SUBJECT_SAMPLE_FACTORS           	-	NN-021	Treatment:RFP_Enza_C13Gln	RAW_FILE_NAME=NN-021.raw
SUBJECT_SAMPLE_FACTORS           	-	NN-022	Treatment:MYC_Enza_C13Gln	RAW_FILE_NAME=NN-022.raw
SUBJECT_SAMPLE_FACTORS           	-	NN-023	Treatment:MYC_Enza_C13Gln	RAW_FILE_NAME=NN-023.raw
SUBJECT_SAMPLE_FACTORS           	-	NN-024	Treatment:MYC_Enza_C13Gln	RAW_FILE_NAME=NN-024.raw
SUBJECT_SAMPLE_FACTORS           	-	QC-blank1	Treatment:NA	RAW_FILE_NAME=QC-blank1.raw
SUBJECT_SAMPLE_FACTORS           	-	QC-blank2	Treatment:NA	RAW_FILE_NAME=QC-blank2.raw
SUBJECT_SAMPLE_FACTORS           	-	QC-blank3	Treatment:NA	RAW_FILE_NAME=QC-blank3.raw
#COLLECTION
CO:COLLECTION_SUMMARY            	media was aspirated and cells were washed with cold 150mM ammonium acetate pH
CO:COLLECTION_SUMMARY            	7.3. Metabolite extractions were performed by adding 500μl of cold 80% methanol
CO:COLLECTION_SUMMARY            	containing 2nM Norvaline (Sigma) as an internal standard per well. Cells were
CO:COLLECTION_SUMMARY            	removed using a cell scraper before transferring cell suspensions to 1.5ml
CO:COLLECTION_SUMMARY            	Eppendorf tubes. Samples were vortexed for 30 seconds and spun at 4°C for 5
CO:COLLECTION_SUMMARY            	minutes at maximum speed to pellet the insoluble fraction before 420 µl of the
CO:COLLECTION_SUMMARY            	soluble fraction was transferred to ABC vials (Thermo Fisher Scientific). 80%
CO:COLLECTION_SUMMARY            	MeOH was evaporated from the ABC vials using the EZ-2Elite evaporator (Genevac)
CO:COLLECTION_SUMMARY            	and samples were stored at -80°C until analysis.
CO:SAMPLE_TYPE                   	Prostate cancer cells
#TREATMENT
TR:TREATMENT_SUMMARY             	Tissue culture plates were coated with 0.01% (v/v) Poly-L-Lysine (Sigma, P4832)
TR:TREATMENT_SUMMARY             	diluted 1/20 in distilled water and washed with PBS to enhance cell attachment.
TR:TREATMENT_SUMMARY             	16D cells were cultured in RPMI base media (Gibco) + 10% FBS (v/v) + 100
TR:TREATMENT_SUMMARY             	units/mL penicillin, and 100μg/mL streptomycin. Enzalutamide treatment was
TR:TREATMENT_SUMMARY             	performed by adding 10μM Enzalutamide (Selleck Chemicals, S1250) every 48
TR:TREATMENT_SUMMARY             	hours.
TR:TREATMENT_COMPOUND            	Enzalutamide
TR:TREATMENT_VEHICLE             	DMSO
#SAMPLEPREP
SP:SAMPLEPREP_SUMMARY            	For metabolite extraction, media was aspirated and cells were washed with cold
SP:SAMPLEPREP_SUMMARY            	150mM ammonium acetate pH 7.3. Metabolite extractions were performed by adding
SP:SAMPLEPREP_SUMMARY            	500μl of cold 80% methanol containing 2nM Norvaline (Sigma) as an internal
SP:SAMPLEPREP_SUMMARY            	standard per well. Cells were removed using a cell scraper before transferring
SP:SAMPLEPREP_SUMMARY            	cell suspensions to 1.5ml Eppendorf tubes. Samples were vortexed for 30 seconds
SP:SAMPLEPREP_SUMMARY            	and spun at 4°C for 5 minutes at maximum speed to pellet the insoluble fraction
SP:SAMPLEPREP_SUMMARY            	before 420 µl of the soluble fraction was transferred to ABC vials (Thermo
SP:SAMPLEPREP_SUMMARY            	Fisher Scientific). 80% MeOH was evaporated from the ABC vials using the
SP:SAMPLEPREP_SUMMARY            	EZ-2Elite evaporator (Genevac) and samples were stored at -80°C until analysis.
#CHROMATOGRAPHY
CH:CHROMATOGRAPHY_SUMMARY        	Dried metabolites were resuspended in 50% ACN:water and 1/10th was loaded onto a
CH:CHROMATOGRAPHY_SUMMARY        	Luna 3um NH2 100A (150 × 2.0 mm) column (Phenomenex). The chromatographic
CH:CHROMATOGRAPHY_SUMMARY        	separation was performed on a Vanquish Flex (Thermo Fisher Scientific) with
CH:CHROMATOGRAPHY_SUMMARY        	mobile phases A (5 mM NH4AcO pH 9.9) and B (ACN) and a flow rate of 200
CH:CHROMATOGRAPHY_SUMMARY        	μl/minute. A linear gradient from 15% A to 95% A over 18 minutes was followed
CH:CHROMATOGRAPHY_SUMMARY        	by 9 minutes isocratic flow at 95% A and reequilibration to 15% A.
CH:CHROMATOGRAPHY_TYPE           	HILIC
CH:INSTRUMENT_NAME               	Thermo Vanquish
CH:COLUMN_NAME                   	Phenomenex Luna NH2 (150 x 2mm,3um)
CH:SOLVENT_A                     	5 mM NH4AcO pH 9.9
CH:SOLVENT_B                     	ACN
CH:FLOW_GRADIENT                 	Linear gradient was as follows: 15% A to 95% A over 18 minutes was followed by 9
CH:FLOW_GRADIENT                 	minutes isocratic flow at 95% A and reequilibration to 15% A
CH:FLOW_RATE                     	200 ul/minute
CH:COLUMN_TEMPERATURE            	35
#ANALYSIS
AN:ANALYSIS_TYPE                 	MS
#MS
MS:INSTRUMENT_NAME               	Thermo Q Exactive Orbitrap
MS:INSTRUMENT_TYPE               	Orbitrap
MS:MS_TYPE                       	ESI
MS:ION_MODE                      	UNSPECIFIED
MS:MS_COMMENTS                   	Metabolites were detection with a Thermo Fisher Scientific Q Exactive mass
MS:MS_COMMENTS                   	spectrometer run with polarity switching (+3.5 kV/− 3.5 kV) in full scan mode
MS:MS_COMMENTS                   	with an m/z range of 70-975 and 70.000 resolution. TraceFinder 4.1 (Thermo
MS:MS_COMMENTS                   	Fisher Scientific) was used to quantify the targeted metabolites by area under
MS:MS_COMMENTS                   	the curve using expected retention time and accurate mass measurements (< 5
MS:MS_COMMENTS                   	ppm).
#MS_METABOLITE_DATA
MS_METABOLITE_DATA:UNITS	Abundance
MS_METABOLITE_DATA_START
Samples	NN-001	NN-002	NN-003	NN-004	NN-005	NN-006	NN-007	NN-008	NN-009	NN-010	NN-011	NN-012	NN-013	NN-014	NN-015	NN-016	NN-017	NN-018	NN-019	NN-020	NN-021	NN-022	NN-023	NN-024	QC-blank1	QC-blank2	QC-blank3
Factors	Treatment:RFP_vehicle_C13Glc	Treatment:RFP_vehicle_C13Glc	Treatment:RFP_vehicle_C13Glc	Treatment:MYC_vehicle_C13Glc	Treatment:MYC_vehicle_C13Glc	Treatment:MYC_vehicle_C13Glc	Treatment:RFP_Enza_C13Glc	Treatment:RFP_Enza_C13Glc	Treatment:RFP_Enza_C13Glc	Treatment:MYC_Enza_C13Glc	Treatment:MYC_Enza_C13Glc	Treatment:MYC_Enza_C13Glc	Treatment:RFP_vehicle_C13Gln	Treatment:RFP_vehicle_C13Gln	Treatment:RFP_vehicle_C13Gln	Treatment:MYC_vehicle_C13Gln	Treatment:MYC_vehicle_C13Gln	Treatment:MYC_vehicle_C13Gln	Treatment:RFP_Enza_C13Gln	Treatment:RFP_Enza_C13Gln	Treatment:RFP_Enza_C13Gln	Treatment:MYC_Enza_C13Gln	Treatment:MYC_Enza_C13Gln	Treatment:MYC_Enza_C13Gln	Treatment:NA	Treatment:NA	Treatment:NA
2-AminobutyrateC12 PARENT	733937	757438	887320	1300817	1224826	1270786	670701	628479	519535	1048418	1107940	988637	662665	635469	599366	1095669	1076747	1154594	530262	482390	501320	947585	975614	848072	0	0	0
2-HGC12 PARENT	7588224	7112736	7510870	7401094	6847364	6358328	6160834	5587758	6117182	5689814	5975808	6838666	5726270	6806494	7385102	4843426	4925022	5496046	5811486	5738358	5655304	5660380	5677294	5398434	16974836	13545817	12149684
2-HGC13-2	243343	303733	369946	992304	833860	709229	125824	144575	64203	130303	312355	243933	102427	73733	124196	192108	240426	194891	0	0	21869	47468	96631	94475	0	0	0
2-HGC13-3	37920	0	31515	68016	96069	65533	0	0	0	52887	23605	0	308307	274264	233189	612793	751486	537607	83949	71863	140976	192651	293201	228614	0	0	0
2-HGC13-5	0	0	0	0	0	0	0	0	0	0	0	0	788763	738089	785357	2077532	2041754	2183799	182495	181439	211321	730248	886110	939708	0	0	0
3-PhosphoglycerateC12 PARENT	162037	196231	179547	366235	360952	467697	276101	193223	221569	358445	341616	335735	1489506	1555056	1453906	3034314	2904009	3112554	1942532	1840877	1900990	2810590	3040470	2768581	222037	0	62925
3-PhosphoglycerateC13-2	115883	20825	43451	220237	293937	264913	12029	23341	0	112170	187331	172573	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
3-PhosphoglycerateC13-3	2457656	2240619	2419568	6469600	5947176	6752244	1719796	1638457	1711475	3550319	3949984	4072853	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
4-HydroxyphenyllactateC12 PARENT	842807	875320	882418	2046588	1890999	2009297	1134219	1115279	1140219	1952588	2228067	1947263	877537	928879	919024	1906947	1803375	2053784	1400884	1231296	1233320	2086138	2027717	2137371	0	0	0
4-HydroxyphenyllactateC13-1	64318	52380	78529	187902	190671	103915	74613	111415	85747	219668	143749	199491	80020	80668	119157	175848	172587	184609	137764	68057	158023	222945	182522	188613	0	0	0
5-MethylthioadenosineC12 PARENT	853146	1041799	923648	1102198	1130799	1025992	1958696	1935785	1683402	1397843	1414419	1403413	4605324	4790597	4653662	6855708	7594842	6990144	4501706	4665504	4387360	6396158	6624622	6255498	0	0	0
5-MethylthioadenosineC13-1	137958	129723	128666	182038	144860	154347	267600	275560	194171	172109	218766	191418	454086	537691	512161	837128	807541	867471	468737	494769	482318	706655	776362	694750	0	0	0
5-MethylthioadenosineC13-2	152955	168528	154592	166905	170993	143515	176277	194651	162452	182522	147410	200463	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
5-MethylthioadenosineC13-3	92781	112894	114433	146803	157947	148116	85931	78614	61816	146442	142520	146341	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
5-MethylthioadenosineC13-4	222195	249116	233467	388977	356879	335273	236164	210356	191091	359744	339130	302639	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
5-MethylthioadenosineC13-5	2735371	2496939	2701345	4244466	3829659	3544961	2317628	2596753	2061445	3861663	4034686	4072265	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
5-MethylthioadenosineC13-6	578964	585890	562705	2385772	2146693	2029859	234841	250273	190146	1247842	1320211	1366688	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
5-MethylthioadenosineC13-7	164701	172442	178643	1244697	1155007	1071905	0	0	0	514442	533007	525732	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
5-MethylthioadenosineC13-8	59506	72201	84733	615983	554860	484715	0	0	0	222700	241601	255382	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
5-OxoprolineC12 PARENT	97156584	90932104	97814824	128150336	126985576	133980152	70456512	67680760	64323988	86754240	91449024	84845424	5125422	5625334	5298464	8793791	8257144	8018158	5112457	4400179	4890596	7098810	6658646	6086476	0	0	0
5-OxoprolineC13-1	5496642	4969782	5431090	7066942	7187386	7529438	4189711	3943216	3773015	4762066	4934040	5150006	535806	487771	614168	783940	898095	875339	575695	516172	518528	609638	654206	639690	0	0	0
5-OxoprolineC13-2	589677	655897	835164	1241668	1325744	1393755	549777	606550	552748	1084560	1028506	1075823	276993	261929	338818	451302	431559	521959	274845	275932	258114	348965	366097	375328	0	0	0
5-OxoprolineC13-3	138728	211721	207074	341294	300302	298572	245712	161820	174182	230354	243264	241052	654093	634400	692179	1260617	1346259	1176629	506224	466373	522204	838885	807734	974163	0	0	0
5-OxoprolineC13-4	32796	37839	86706	201057	224081	284889	31379	42644	68503	115609	87720	133545	903802	836042	810824	1070660	1141292	1246548	822076	801254	771387	1093721	894503	909219	0	0	0
5-OxoprolineC13-5	0	0	0	0	0	0	0	0	0	0	0	0	21528980	21105162	20800878	27027350	27169354	26628342	18914514	17332534	18002694	24272040	22668122	21736924	0	0	0
6-PhosphogluconateC12 PARENT	0	0	0	0	0	0	0	0	0	0	0	0	338545	297047	333623	289864	330151	511834	228765	169113	229130	312645	300658	266789	0	0	0
6-PhosphogluconateC13-5	21975	89657	63175	202269	113726	90760	0	16947	0	17413	20202	60892	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
6-PhosphogluconateC13-6	536439	473370	435293	1025142	878114	982485	177573	200205	166714	312411	450632	466434	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
a-KetoglutarateC12 PARENT	1161749	1494242	1424005	1775975	1792060	1542513	896496	945543	994095	864248	1064324	1497196	698637	727057	902515	1055026	896030	749634	791217	682082	782664	547575	971120	795618	1151375	739366	695547
a-KetoglutarateC13-1	61348	107232	83466	0	0	99091	42095	46521	70462	0	47886	91336	53409	170505	149861	191821	243316	192269	183539	72824	135510	111615	201662	216081	0	0	0
a-KetoglutarateC13-2	282435	377158	357084	700484	526333	443536	217362	255175	315045	332745	287307	404271	119184	94700	172524	273876	252134	180101	58637	112943	95653	106597	155156	144234	0	0	0
a-KetoglutarateC13-3	27993	161746	88516	117201	164961	0	46812	27353	66931	77017	43909	67095	201094	235550	293069	493976	466562	423509	119092	145985	179927	141470	263857	324549	0	0	0
a-KetoglutarateC13-4	25914	0	39775	103110	104623	47975	0	14897	17321	35587	15626	47101	0	14262	39835	51843	47726	59949	0	0	11969	15232	21632	35559	0	0	0
a-KetoglutarateC13-5	0	0	0	0	0	0	0	0	0	0	0	0	424458	436214	601429	1110882	1068250	814445	199188	162933	218020	467571	678794	701847	0	0	0
Acetyl-CoAC12 PARENT	50829	57947	56357	57680	49762	53962	113598	106744	110587	54158	55064	58064	320008	305031	311420	495407	456481	505417	335021	324417	326616	368511	376347	377270	0	0	0
Acetyl-CoAC13-1	17343	17720	19773	17275	16341	18857	35703	31621	33835	17676	18216	19649	97752	88760	88174	141564	133367	151306	104377	98969	96427	114698	112481	111905	0	0	0
Acetyl-CoAC13-10	1186	2001	1978	16531	17119	19970	0	0	0	4951	5226	7540	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
Acetyl-CoAC13-2	31329	30566	35052	35072	37549	34374	48538	46941	44294	34551	30099	33998	56675	52189	56264	84087	79472	81902	52293	48261	46903	55233	56997	62526	0	0	0
Acetyl-CoAC13-3	12642	13611	15678	18781	18004	19205	18037	15195	15280	14817	13102	14238	15481	13002	13915	20745	21836	20229	11290	11757	10918	12787	5207	14480	0	0	0
Acetyl-CoAC13-4	21583	22387	17614	25455	23480	27021	21356	22399	20085	18095	21866	19069	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
Acetyl-CoAC13-5	169093	160767	167021	191990	181086	193967	132815	126310	124167	145565	162703	160755	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
Acetyl-CoAC13-6	60974	59418	69536	143512	146127	142823	44770	38483	35226	80260	79668	87741	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
Acetyl-CoAC13-7	71589	72211	79069	154260	160600	158770	48805	45011	48841	87831	96218	95900	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
Acetyl-CoAC13-8	25116	26262	27183	93047	93139	94697	10432	10803	10119	38859	46445	44256	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
Acetyl-CoAC13-9	9817	9194	10066	45096	41604	46345	1979	2887	1650	15367	16529	16949	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
AcetylcarnitineC12 PARENT	187473424	189829120	199130240	150307696	158711568	155288816	183364816	170744704	173694736	151839424	153151424	147772816	257925616	239330608	261141168	225957120	221074560	241364016	253422768	225452880	230014896	233616896	233567856	230879024	0	0	0
AcetylcarnitineC13-1	21977294	21789774	23521514	19912826	21038622	20324410	21314290	20225830	20774134	19337192	19308502	18568692	27844962	27229638	26989666	24933504	24219384	26554550	27180950	23273774	25136970	25704134	25676034	25204786	0	0	0
AcetylcarnitineC13-2	88137808	88993568	96387208	126390912	132681240	130729344	71408352	66349952	68638208	108191240	110168088	106120352	35668432	34851756	36416920	28650394	27810840	30791654	23417984	19407434	21328482	29318794	29414496	29462976	0	0	0
AcetylcarnitineC13-3	6175334	6489036	6896099	9424449	9913796	9842041	4960720	4621848	5015625	7955296	8087653	7781988	2158083	2057409	2216252	1573349	1548256	1899480	1258575	1097357	1036272	1692993	1643445	1603501	0	0	0
AconitateC12 PARENT	1666425	1787708	2033464	1451389	1405423	1253892	1196731	1208853	1312812	714246	931811	830546	1847324	1755738	1843594	1605108	1431172	1478339	1785454	1667928	1606318	1046732	1052850	1047946	0	0	0
AconitateC13-1	325988	355641	332344	119152	243743	203160	233910	315647	195621	212777	125218	182820	471345	409720	558443	443417	552482	495576	536390	355664	425941	471768	384256	353374	0	0	0
AconitateC13-2	1160242	1147782	1290147	1446809	1461612	1489716	679505	848154	659065	860379	818764	1051527	509419	471772	553547	683514	724392	759848	398513	462480	444398	464134	529694	426609	0	0	0
AconitateC13-3	198519	324685	215196	357962	359290	373892	197646	330364	290285	177445	290076	308914	618557	451278	519356	532303	548116	565299	253294	250415	284215	232570	289980	340388	0	0	0
AconitateC13-4	169362	277381	330517	462876	392721	422196	178233	165491	159345	268169	243552	223928	605248	510910	502580	815530	890981	894393	218262	264589	238229	371071	417671	449126	0	0	0
AconitateC13-5	106337	85524	177173	181762	277542	312357	41633	73846	71060	76234	100872	106874	599961	551072	711761	499225	522424	483537	333915	280602	254115	295118	238071	284553	0	0	0
AdenineC12 PARENT	119077	138324	139087	95061	90230	116353	97857	121565	118228	103790	85896	100178	182756	253827	282183	173108	191007	186104	233944	156888	197111	243846	170302	148233	35494	53226	64789
AdenosineC12 PARENT	61883	86874	59333	132606	69194	48013	131877	148258	154954	64036	53576	94475	71533	87827	132381	352827	331282	334450	226350	226960	187521	233977	121710	182277	0	0	0
AdenosineC13-5	189312	215276	212001	441758	262967	246929	141484	196391	175280	190684	174809	215045	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
AdenosineC13-6	49279	49161	32821	235602	140029	136397	20568	0	22118	60118	62553	85291	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
AdenosineC13-7	0	0	0	136565	65207	63107	0	0	0	28857	6632	15257	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
AdenosineC13-8	0	0	0	64126	35704	31802	0	0	0	4964	4118	4875	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
ADPC12 PARENT	713387	827112	838545	440594	625060	583103	1087559	1196202	1240665	856236	737191	774025	3431057	3470825	3483518	4729268	4233016	4028428	2699670	2716046	2689797	3760144	2821743	3872072	403660	0	24033
ADPC13-1	54882	44559	76498	50849	24708	0	54844	165279	156755	101448	16917	33570	340498	414030	290710	445785	480176	539962	323467	254933	340822	554221	198545	425606	0	0	0
ADPC13-2	53813	84368	85243	48294	32955	30555	113247	67003	103839	109692	49265	41089	27577	31741	48995	76878	25217	0	0	0	0	22754	0	43173	0	0	0
ADPC13-4	134512	208113	77850	173102	146494	97155	138727	116160	129968	198843	179038	131070	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
ADPC13-5	2043331	1988677	2289691	1694746	1949062	1825644	1631822	1420587	1589585	2199695	1942232	2213807	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
ADPC13-6	448591	368866	388558	933327	1145294	1198274	83265	155192	179809	704148	580612	605898	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
ADPC13-7	152515	136416	167805	548402	441487	632312	0	0	0	267867	235877	331369	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
ADPC13-8	23426	26392	27104	216730	382611	292863	0	0	0	57518	60943	107859	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
AlanineC12 PARENT	14980824	14522572	14318277	15248975	15990371	15327645	16968906	16733480	16500913	13908213	14205855	13515639	31591936	29901888	30948346	46820192	45005452	49233932	29870710	28787346	28809142	33561412	34952716	34900928	0	0	0
AlanineC13-1	645974	658384	675609	845429	851519	883376	755164	725612	801442	690367	694731	640768	1232212	1204922	1129520	1896039	1812261	1970588	1240302	1108498	1249012	1293556	1488380	1356614	0	0	0
AlanineC13-2	1047417	929003	920419	1679596	1724918	1835891	726734	720253	777074	1130518	1123373	1011100	312731	252082	290536	404644	424303	480237	219480	273740	224808	285552	294619	297794	0	0	0
AlanineC13-3	22661822	21663290	22725720	39726784	41613052	40995044	16033837	15414853	15505952	26657968	27359630	26778710	732085	636530	639597	1355342	1233249	1390394	520733	503397	503979	808559	845468	790893	0	0	0
AlanineStd	1171145	1230985	1165985	1073807	1186263	1137207	1258062	1103123	1055802	1091309	1246564	1106636	1085419	1009751	1138544	973350	914365	1002848	1105419	1195370	1129450	1073536	1093014	1026897	0	0	0
AMPC12 PARENT	655519	696876	537047	994152	936441	847375	1675623	1403494	1242659	997609	1159045	1121729	2769038	3011021	3790264	5804164	5105182	5213519	2909642	3405479	3245323	5088596	3868540	4412786	0	0	0
AMPC13-1	106237	73739	82269	138495	108583	145870	189325	148733	179675	122726	184765	111336	313582	360606	367094	600430	566533	557828	306379	380655	457302	539694	429937	462246	0	0	0
AMPC13-2	98117	95501	93879	189357	151255	119186	126824	133874	126441	156784	144508	110744	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
AMPC13-3	72456	91914	113010	146570	129061	142909	63823	83049	30798	116481	183474	114199	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
AMPC13-4	218755	116627	207042	306269	329579	295090	190584	131136	145612	308821	251556	281699	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
AMPC13-5	2181952	1997158	2228152	3590616	3193823	3090182	2020316	1651490	1557859	2805646	3309709	2825799	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
AMPC13-6	426147	416745	476863	1741462	1798028	1688596	199530	128719	144105	816708	1055806	942433	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
AMPC13-7	166351	161614	139138	939938	927928	864260	0	0	25385	387665	421685	411721	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
AMPC13-8	29477	13642	12840	478471	432457	473198	0	0	0	148346	168323	196049	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
AMPC13-9	0	0	0	118479	148252	118160	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
ArginineC12 PARENT	69985304	58862772	57545428	92909600	97367784	101755720	60983520	59135028	57381740	86041416	80522824	73302120	52727172	46793856	47268756	79242000	67337320	68599944	49639968	47705516	46882528	60401968	66861780	61129676	0	0	0
ArginineStd	4251514	4225344	4101470	4204887	4224012	4187938	4200600	4129870	4003233	4460548	4045303	3886420	3927863	3821623	3932986	4251317	3691149	3781972	3831474	4088757	4006225	3341368	3984543	3714495	0	0	0
ArgininosuccinateC12 PARENT	849790	847164	840431	1426666	1427319	1523779	505676	450301	538626	821098	1062450	1015166	390095	416423	320554	492346	465609	527221	281454	260757	348825	353941	434078	392458	0	0	0
ArgininosuccinateC13-1	119376	100316	67490	248330	179038	253928	103070	89272	58532	184335	170034	167857	80469	87088	96137	164412	190772	180487	29873	72860	75298	112312	157347	103932	0	0	0
ArgininosuccinateC13-2	157185	179616	205666	278237	305475	329408	76253	116910	25961	224419	198956	161459	125053	129475	136840	229379	218668	261350	64201	53321	72757	224803	167935	188238	0	0	0
ArgininosuccinateC13-3	77523	59447	66235	234426	195788	211301	21062	65792	31932	83497	109198	109788	48127	94463	49944	164642	180342	176905	29913	17277	33692	149104	126900	126463	0	0	0
ArgininosuccinateC13-4	13449	11075	23968	28242	14384	20158	0	0	0	0	0	14001	245335	213237	191607	378924	373465	437383	79022	59189	61209	280244	232077	274768	0	0	0
AsparagineC12 PARENT	207115376	212730096	219127024	305945760	289788320	317505568	200061968	200420976	188715328	242535088	246134256	247526896	187733824	185088976	192625456	260047424	240751920	285303648	176229968	168377280	167279776	205071568	210070016	199732160	0	0	0
AsparagineC13-1	10026980	10415297	10772653	14892375	14347673	15052224	10291676	10116293	9999779	11476533	11850397	12067475	10000445	9607766	10340957	13825624	13049008	14799315	9609376	9157873	8817623	9914947	11153945	10468704	0	0	0
AsparagineC13-2	2433309	2482287	2493332	3770807	3509523	3914516	2340107	2415609	2240938	2439972	2474834	2877647	2958412	2374858	2875549	3870795	3662808	4263339	2306747	2048782	2439908	2617144	3008627	3183631	0	0	0
AsparagineC13-3	1143628	1166476	1221562	1779122	1735472	1863559	1004226	1020892	1067924	1124494	1239122	1231676	2221850	2312471	2426312	4053021	3605492	4469048	1903671	1760154	1545795	2582011	3056313	2799219	0	0	0
AsparagineC13-4	124448	146135	197261	312910	330015	362904	143457	105392	88094	124037	140650	185663	5709136	5641686	5831510	10045295	10303563	12050017	4401486	4461940	4460812	7893664	8185424	7752902	0	0	0
AspartateC12 PARENT	78806560	76294536	80131560	79853848	74417952	78373112	70121192	71077800	66506068	55470324	57949136	54930796	36798816	37722228	39485376	38756624	40192228	38994660	50522412	47278528	48554048	32494536	32545696	31664064	0	0	0
AspartateC13-1	9607059	9553620	10832749	9927983	9175581	9442381	11427528	11275789	11270197	6706562	6943064	6914860	9651765	9500979	10363715	11192264	11645431	11717973	12934416	12302328	12107037	9346737	9757062	9912147	0	0	0
AspartateC13-2	16988094	16356160	18235154	21314442	20428442	21548586	15931808	15205743	14555632	13155821	13303892	13259656	13222285	13119388	13885824	16975952	17568866	17615380	13774705	12865939	13351484	13287347	13696139	13791247	0	0	0
AspartateC13-3	7637504	7587022	8321506	11336788	10276260	11441441	8929436	8123106	8254282	7242092	7154510	7105780	8510609	8681987	8895412	9787496	9675191	10254724	6888614	6167360	6419306	6588244	7094550	6987542	0	0	0
AspartateC13-4	1451798	1446501	1658047	2822687	2565644	2588564	1223635	1217824	1128223	1396722	1327917	1159655	18325916	18566308	19589282	26091270	28223960	27173706	14349544	12511327	13429947	16483784	17099536	17524430	0	0	0
AspartateStd	6903834	7279562	7229778	6291078	6253182	6540218	7539498	7458424	6944730	7442088	7746454	7083114	7906348	8140366	8693208	7041882	7637288	6934442	8135408	7843784	7696108	8805052	8880559	8525447	0	0	0
ATPC12 PARENT	9300303	9215209	9622841	9345187	8385882	8953483	20840990	21847010	19869150	11617292	11864701	10853812	55286724	54874316	56346736	78907624	81279480	85969448	63455364	57156988	60768384	70063520	72178984	66989004	0	0	0
ATPC13-1	1344034	1256040	1356929	1139686	1234557	1433766	2863733	2734043	2539300	1703850	1723897	1501292	6702648	6615386	6572912	9528427	9935316	9858313	7703012	6654650	6464920	8183642	8225996	7591786	0	0	0
ATPC13-2	1610875	1671498	1697138	1486920	1429539	1503778	2728876	2388313	2261502	1761393	1656710	1522052	1626661	1827070	1827190	2539640	2796883	3086844	2049398	1823536	2042820	2455130	2119658	2113819	0	0	0
ATPC13-3	953167	930399	1003310	1431272	1478213	1395485	1039004	1029502	1020767	1134872	1317791	1077712	429450	344390	336034	472995	470844	449296	352675	254811	274875	315102	412568	337964	0	0	0
ATPC13-4	2480496	2428645	2503444	3052787	2736804	3232960	2313652	2647222	2268803	2738150	2881393	2781917	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
ATPC13-5	26026266	25742438	27210334	31900250	29372026	31654822	24519450	25572128	23611224	32056552	32284310	30054342	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
ATPC13-6	5707874	5969566	6325838	18434794	16882108	18960338	2802045	2955007	2590104	11080200	10895965	10946296	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
ATPC13-7	2271772	2849512	2789668	10163360	9314590	11302028	1263545	1055417	1025530	5380244	5470248	5186014	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
ATPC13-8	848901	883007	1007492	5133574	5151888	5311276	153688	164133	76682	2113948	2332180	2307038	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
ATPC13-9	108828	153230	257588	1777324	1331763	1785073	0	0	0	607859	592427	537139	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
CarnitineC12 PARENT	119479832	119142008	124518720	106340520	104796088	104443136	205462896	203132400	203404032	123479040	125575528	122439416	145057104	143357712	154503344	120828904	119859584	133005568	229587584	202809456	217211968	130200704	133727816	123647424	0	0	0
CDPC12 PARENT	495723	502888	529163	628907	654639	655315	1013689	1095251	1117772	798290	853188	895455	743400	720520	900081	1172248	1186773	1325549	1272657	1062916	1197930	1141896	1379594	1210834	0	0	0
CDPC13-1	0	0	0	31210	0	0	90448	50001	80563	0	61763	114380	126030	130578	144769	237909	176362	265153	104163	124141	129866	253523	241507	187165	0	0	0
CDPC13-2	0	0	0	13809	0	13328	13032	0	0	17463	0	0	15026	36397	18021	203498	160756	217364	15752	19690	0	92230	116847	172229	0	0	0
CDPC13-3	0	0	0	0	0	0	0	0	0	0	0	0	120452	103600	208718	435248	503728	559604	0	0	0	408441	395646	494634	0	0	0
CDPC13-5	220398	317330	395420	1048760	976360	1201561	69459	128550	134041	748086	814803	913464	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
CDPC13-6	44724	52949	33026	229231	91338	262651	0	0	0	130281	105562	133265	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
CDPC13-7	14708	16718	17072	206128	165086	239196	0	0	0	59966	114109	87699	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
CDP-cholineC12 PARENT	240052	258225	282403	72028	67303	59903	295030	317568	256873	67735	76605	71706	224296	204808	236143	60915	81546	80000	232037	244438	242205	61831	84680	74674	0	0	0
CDP-ethanolamineC12 PARENT	100986	81590	130321	17410	12736	12339	561538	504466	588746	41185	37702	13029	338301	277335	233270	52720	66096	60134	1292629	1367096	1183849	152553	141594	186462	0	0	0
CholineC12 PARENT	9608110	9157507	8533811	4910106	4478416	4785590	19598288	17605530	17659948	8452026	8575526	8491565	16025130	14135374	15117253	7487256	6511216	7501958	29394032	28994244	28133978	13372114	13205522	13710314	0	0	0
CitrateC12 PARENT	331752581	334944069	326564037	193184373	181508565	190955029	379515557	376155333	353059749	182194357	194618181	185637573	290805957	284168613	290292453	191978965	190104917	192198533	351769285	348354789	340196325	167516629	185079221	167023829	0	0	0
CitrateC13-1	48889396	49118432	48313344	33003748	31093724	32411556	57960708	55745620	54034308	29546198	30643054	30464174	69192940	67730268	70163804	61172664	62464904	65385824	67000164	65156936	65091584	53479956	59249764	52170104	0	0	0
CitrateC13-2	172821279	176585695	176028047	211636959	201406031	215041439	126947631	124522383	119229991	148463311	156084399	144336783	68856871	68350903	68379583	78580431	75269903	80089599	47200515	46337539	45284483	61714015	67406415	62481103	0	0	0
CitrateC13-3	40296111	41781583	41840715	47097299	45303763	48957055	34774843	33810131	33176319	33460691	35714683	33126539	66484439	65906871	66954703	65115183	63708371	67144407	40305667	39444267	38468159	50840143	55116515	51083807	0	0	0
CitrateC13-4	30395211	34254239	34824503	58122215	54450631	60946335	19007697	19401709	18503771	32410023	34598491	34509647	78935163	79737099	79535515	102461387	100856219	110628219	37637495	36375407	37233799	64509247	71385483	66707963	0	0	0
CitrateC13-5	14516773	14672355	15439788	28310760	26329984	30454768	8741847	7780921	7708644	15860462	15661416	17100022	77028040	75152808	75305648	55478828	53070948	53699108	33175908	32699672	32667096	36277856	40665300	36601468	0	0	0
CitrateC13-6	2297992	2268821	2582916	5982928	5826672	6262426	858943	1021391	958609	2389295	2594991	2871229	3615948	3804318	3488121	4650808	4358806	4623674	1346450	1442531	1359014	2350718	3001084	2692033	0	0	0
CitrullineC12 PARENT	1716330	1580959	1521956	2409229	2682690	2457665	1382341	1406603	1303651	1400319	1379836	1403801	1399779	1340841	1334084	2022551	2014434	2328138	1207145	1011020	1214620	1277325	1171805	1102305	0	0	0
CMPC12 PARENT	81192	81699	101267	229691	225245	0	116602	210152	307070	91229	190178	202509	38711	120180	148333	386888	298698	265479	149046	65931	243339	116799	325330	158441	0	0	0
CMPC13-5	0	0	32620	73528	144367	123048	0	0	0	0	43610	49198	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
CoAC12 PARENT	70506	73232	77568	71519	64805	72591	133501	134239	108208	74231	73813	65657	382296	406243	395297	511962	513284	565938	373431	331874	366262	412488	379914	351030	0	0	0
CoAC13-4	20639	20340	22710	22740	21475	27244	18118	20509	14175	20891	19392	20539	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
CoAC13-5	210439	219048	231524	232180	208835	262540	161308	157592	142681	190980	188791	181875	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
CoAC13-6	69148	79247	82629	152905	145489	164996	46036	49654	42851	88727	81246	81850	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
CoAC13-7	21997	32678	39885	85236	78750	91871	19921	17181	11451	44687	39284	37954	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
CoAC13-8	9716	12109	13249	42234	43097	51220	0	0	2820	16609	17368	16482	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
CoAC13-9	1641	1701	0	16109	14558	16188	0	0	0	5179	2587	1842	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
CreatineC12 PARENT	769665088	771300672	787987520	995427072	976156864	1055056384	723520000	694395392	663531200	735706880	800319680	782305536	732394176	705782336	675740480	848996032	841137344	829941824	631899264	582717568	619425408	667659584	682773824	618713152	0	0	0
CreatinineC12 PARENT	206343568	190933360	179624496	226607888	240051632	245515184	194212944	178548848	173924208	221151680	217524992	195698000	220733328	194878160	177204512	227675904	214524240	249413136	195932336	180427280	182948272	221014576	208054224	163407392	0	0	0
CTPC12 PARENT	1172998	1169953	1099359	993355	1009759	1124173	2268041	2290396	2040117	1337727	1378634	1460751	1766241	1995674	2077438	1826275	2313112	2363966	2932233	2740124	2584444	2431174	2366039	2438427	0	0	0
CTPC13-1	110160	118955	101461	92348	26318	81995	224098	219075	248638	77226	155181	156524	330864	280457	319620	387680	510223	561620	362401	320671	301788	573701	386609	454495	0	0	0
CTPC13-2	78860	17194	0	25004	0	20135	26226	29219	24010	29248	43332	21070	224069	167708	260785	404692	410254	468487	101509	175361	98365	376163	319270	322718	0	0	0
CTPC13-3	0	0	0	0	0	0	0	0	0	0	0	0	407560	334992	499823	1141901	1076371	1273333	129785	219016	132162	855930	783429	906786	0	0	0
CTPC13-4	21876	58429	34113	201039	83318	107476	0	0	0	28207	103429	27428	17569	19378	17734	60774	53726	48888	0	0	0	19083	27069	31933	0	0	0
CTPC13-5	721544	873626	721768	1671343	1788827	1682523	332188	262362	206199	1226597	1419867	1465705	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
CTPC13-6	99381	118371	120147	404491	407915	373015	18900	22510	0	275473	259354	216185	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
CTPC13-7	59043	50191	132059	404388	308736	341290	19776	0	0	226306	236630	162921	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
CTPC13-8	0	0	16065	82332	67113	90730	0	0	0	19226	26561	41874	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
CystathionineC12 PARENT	4152237	3596184	4398888	6281406	6423532	6622088	6481290	7104642	6966166	5768628	5257364	5675954	4843712	4212262	4563058	7710494	7439150	7732228	7467836	7522908	6356240	7970928	7120972	7868374	0	0	0
CystathionineC13-1	532812	499952	565505	1316043	1437551	1386547	878333	944903	888973	1087830	1166708	1082324	320922	290263	302004	558145	548481	541057	451001	573871	547080	562536	466670	511873	0	0	0
CystathionineC13-2	186580	171333	221593	555164	605175	675043	268582	267236	267988	428841	515652	519537	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
CystathionineC13-3	561670	549552	647458	1429022	1448887	1447408	572833	475405	462366	866977	787732	776627	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
CystathionineC13-4	61240	84213	82143	211489	230720	263284	82948	67430	0	143891	162716	140352	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
CystineC12 PARENT	66488	26198	27744	146804	102136	132803	154762	128124	108855	174888	235837	170474	72187	91856	77492	110353	196917	107508	77249	70999	80412	187980	175054	112736	0	0	0
CystineStd	34969	29924	14437	11972	15246	0	32158	13271	51229	9994	10382	0	45249	57057	16599	12464	10872	0	32400	17608	41815	0	22174	17864	0	0	0
CytidineC12 PARENT	85645	91708	100295	107760	103291	0	245413	225343	206036	149564	133211	153074	122096	100355	92735	121250	92991	124109	226687	249222	213675	131233	142121	155846	0	0	0
CytosineC12 PARENT	1085107	1041111	1059358	1031147	1063357	1158315	915380	978588	950786	1151375	1205738	1080505	833894	799611	738342	897739	822180	855306	807987	711442	760475	782544	677039	668578	0	0	0
CytosineC13-1	98954	85911	84354	118880	138669	142556	64770	62855	57854	115989	114226	102428	81751	75907	60335	104174	121808	112140	57295	54612	40600	81776	66196	81733	0	0	0
CytosineC13-2	51131	47702	56905	116043	94432	122220	24209	23304	6939	58786	54144	69259	55708	58399	49060	125615	127885	112999	5928	25333	18981	73997	73579	67061	0	0	0
CytosineC13-3	6409	16593	14549	41522	47556	48735	0	0	0	13764	15553	16263	148461	147044	148806	380293	406927	430443	50069	53774	58511	276047	247524	228357	0	0	0
DeoxyadenosineC12 PARENT	103351	74450	84456	96274	110955	99508	104326	118965	93867	106122	83347	89687	102225	106472	128195	140197	135419	144754	91617	99228	98553	107642	112690	102355	0	0	0
DeoxycytidineC12 PARENT	319004	364760	337317	159570	316798	346242	353006	352467	369144	221030	348038	259184	399074	248607	331553	358361	353756	348922	292015	323432	318409	299486	225515	361059	145896	107347	86275
DeoxycytidineC13-5	109713	108549	0	173226	110263	140590	0	0	0	137678	125160	175029	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
DeoxythymidineC12 PARENT	68928	57391	49613	21495	52286	21741	170903	112760	129823	57718	76994	30065	88512	55800	44445	51096	19250	36010	119306	82556	162748	77370	84933	69352	0	0	0
DeoxyuridineC12 PARENT	40980	17674	17117	0	16431	0	90868	92751	59207	0	18727	0	50707	0	17081	0	17705	0	83595	58786	64106	15249	0	0	0	0	0
dGMPC12 PARENT	0	0	0	0	0	0	0	0	0	0	0	0	107777	159776	81576	253145	218375	230136	251672	275511	292685	383800	486326	475062	0	0	0
dGTPC12 PARENT	0	0	0	0	0	0	0	0	0	0	0	0	268184	277777	258102	405886	361581	244617	259369	203972	202732	324122	410191	340588	0	0	0
DihydroorotateC12 PARENT	381469	386976	375347	855796	727537	746117	98455	91964	78727	485153	447744	467778	186476	215376	174171	311428	377096	302309	40211	40258	48109	163546	227870	240389	0	0	0
DihydroorotateC13-1	25176	44887	17318	86570	95844	25294	0	0	12565	39789	37877	36174	15153	29904	41168	84398	82954	45601	0	0	0	34159	48872	40521	0	0	0
DihydroorotateC13-2	47936	56354	44332	165818	188531	190921	13943	13688	0	47630	93942	67477	0	44098	46249	117563	155326	154846	0	0	0	38308	92603	55014	0	0	0
DihydroorotateC13-3	0	41485	45129	123564	174271	138557	0	0	0	77573	43483	24086	34633	52746	47931	159641	146157	184279	0	0	0	86993	104638	32452	0	0	0
DihydroorotateC13-4	0	0	0	20967	13966	0	0	0	0	0	0	0	54140	86924	70220	285165	274431	255845	0	0	0	116254	141707	117623	0	0	0
DimethylglycineC12 PARENT	85400	87687	87244	95646	108371	124125	109225	82325	77631	104615	100718	84861	86742	89625	86904	124020	111662	118340	69481	79974	80997	86556	100263	86011	0	0	0
dTMPC12 PARENT	45971	42398	56676	0	0	0	26058	43005	76979	77225	43752	77942	74460	70087	0	0	0	35012	165699	127664	110068	235481	102811	159210	0	0	0
FolateC12 PARENT	381441	226914	234165	205292	279406	353765	131816	220009	166300	231531	205616	117063	175879	171870	121471	206406	231344	218630	273047	155614	139080	251194	199976	248905	0	0	0
FructoseC12 PARENT	9593019	6948006	7151734	8118368	8729583	10015416	5063236	5242864	4903868	5995012	6631124	5227960	4871008	5425654	4793636	7340974	7314406	6965948	5459660	4265482	4375164	6430286	5734048	5100902	0	0	0
FructoseC13-1	642473	467485	470272	512914	588765	589101	309551	354723	414208	417918	407808	327060	325138	303277	317152	504185	466155	406826	383639	288898	254008	458067	354503	349748	0	0	0
FructoseC13-6	713638	698949	793869	1009755	864002	952803	594540	592965	577180	521460	516405	598894	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
Fructose-1,6-bisphosphateC12 PARENT	460625	391145	562687	602836	637324	617688	211004	164520	233928	216008	357204	332919	3943913	4370887	3880543	7415274	5488873	8121178	3662712	3461229	3397738	4780758	5022412	5089270	829721	0	244803
Fructose-1,6-bisphosphateC13-3	369613	293671	329004	389003	225697	338762	68646	100518	58098	150909	191474	150804	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
Fructose-1,6-bisphosphateC13-5	813796	810148	897692	1540160	1375467	1326093	439686	356687	356080	538963	566738	431096	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
Fructose-1,6-bisphosphateC13-6	11721491	12474608	14358196	19587574	17719456	18982472	4620742	4914378	5331968	7158046	7786688	8483067	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
GABAC12 PARENT	1799513	1980737	2038863	3116393	3218949	3482245	1164096	1235592	1032636	3061887	3128508	2934694	2365785	2547610	2300059	3647103	3694021	3605047	1299695	1182133	814291	2959861	3104892	3015167	0	0	0
GDPC12 PARENT	421528	214046	273572	371276	346270	285241	693667	619689	681486	431990	455278	424352	1471788	1575626	1959988	2577248	2679159	2231465	2019403	1951605	1811036	2455465	2230409	2418316	883894	37057	419564
GDPC13-1	0	0	0	0	0	0	0	0	0	0	0	0	146024	203545	235930	295835	333863	237101	182312	216541	240543	303625	272699	319178	0	0	0
GDPC13-4	64727	46105	46884	48424	97052	54692	17628	14352	75637	164758	121244	146354	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
GDPC13-5	1089840	925719	914345	1419357	1373476	1038125	1038634	952888	1079136	1229047	1400821	1451609	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
GDPC13-6	357956	345837	415067	1114055	905394	791522	97150	88345	231725	538901	686559	464590	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
GDPC13-7	87774	135290	99888	716804	635419	593248	0	0	0	293612	383095	314055	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
GDPC13-8	21458	17488	19211	345691	360205	230030	0	0	0	104952	53227	69581	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
Gluconic acidC12 PARENT	4050526	3728541	3941878	5194986	5227058	5364158	3572690	3274017	3316895	4534152	4568312	4484637	6911684	6369470	6219238	8307663	7986190	8492222	6970490	6659412	7009852	8142457	7401044	7483898	0	0	0
Gluconic acidC13-1	303562	298836	299806	332121	368082	436713	175501	230724	225941	321198	292219	334405	437268	469400	445175	523192	493295	603613	490061	374247	416957	547357	551291	519375	0	0	0
Gluconic acidC13-3	49131	71444	84232	77130	81715	65762	159001	178372	135225	73306	80775	134365	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
Gluconic acidC13-5	385312	360663	390100	609254	553501	604684	345347	332181	300688	346988	397679	369794	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
Gluconic acidC13-6	3280969	2891617	3236400	4793078	4696100	5010607	3177704	3685013	3299981	4135256	4180561	4250698	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
GlucosamineC12 PARENT	1591763	1010728	862511	818754	1001353	1438154	634505	629140	524252	881825	731523	390019	995688	813721	612832	856263	813244	1052474	740063	595891	554246	932578	708633	425732	0	0	0
GlucoseC12 PARENT	2990231	2343918	2102056	2232231	2301816	2632602	1872437	1797605	1826975	2223497	1630203	1594218	52828036	46533956	47820208	64191616	63247600	61583148	53892572	44720148	43615304	62931124	53595808	44985808	0	0	0
GlucoseC13-5	8337906	6193576	5971672	5666432	5804622	7404080	5156326	4806412	4924130	5176348	5748988	4329570	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
GlucoseC13-6	117781016	85531736	81765512	82248952	89639936	104443904	71956128	70084664	65689268	76846328	78594464	58816004	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
Glucuronic acidC12 PARENT	535109	438135	382162	465107	493975	525742	416511	400126	414159	373066	299051	343392	695665	819524	602314	894828	808832	902151	1296938	1147654	1236591	987485	1020747	931566	0	0	0
Glucuronic acidC13-5	16545	13249	31383	14149	29737	25857	61628	74939	40371	31979	18529	14121	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
Glucuronic acidC13-6	343848	390913	434641	556810	516532	451434	790994	689482	627068	606654	585737	693680	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
GlutamateC12 PARENT	228361008	231188224	237501632	313197152	298435328	304003392	249478896	247183536	240836608	273571904	284665216	271730016	110177464	111250312	113532096	106967360	105691904	110163328	168499344	171246288	167044752	105345600	107837656	109660792	0	0	0
GlutamateC13-1	26826726	27893454	29420262	31147750	30002670	30660426	43149204	43451936	42916516	30601054	31716848	29981114	35388576	35444404	37608096	39442844	39296856	42065120	53781600	52777456	51645716	39558004	41780588	41912788	0	0	0
GlutamateC13-2	69123976	72353992	75914152	103322744	99070504	103097512	95085704	92551424	92605352	93185672	94830112	94825472	29670206	29343994	31438224	35687752	34471028	36727684	38391116	37298508	35954716	35428908	36455356	36322448	0	0	0
GlutamateC13-3	20321294	19955078	21640826	28416890	27226882	29940714	26538570	25789530	25449072	23768990	24281792	24544600	53964004	54805392	56734096	75351360	73670712	77484624	59522844	58258956	57250132	67338848	69978144	70452296	0	0	0
GlutamateC13-4	13499009	13873659	14969917	24663406	23177744	24846194	14771593	14477192	14536963	17524254	17855632	18020060	7695474	7825178	8364104	11453039	11094593	11298997	6289998	6380920	6358016	8771143	9154973	9292421	0	0	0
GlutamateC13-5	4712368	4654784	4884957	8962135	8192070	9496167	4651184	4470450	4487244	6104434	6191210	6199552	116978840	121288024	120358976	183659392	181700096	186636976	80017000	82587200	80239624	137992960	140598576	140205888	0	0	0
GlutamateStd	3891883	4139685	4066317	3930693	3657863	3675236	4000574	3892683	3722636	3963262	4038193	3704175	4474642	4900606	4434318	4756246	4645270	4197286	4345794	4458103	4548248	4734358	4716672	4440679	0	0	0
GlutamineC12 PARENT	729359424	711467712	727462848	632335360	605422912	657656832	924830144	890425344	897226048	731951808	727274304	736108800	67929888	67401720	65887344	59547516	64256540	64902240	123624968	112769720	113354624	59444812	59954932	62064368	0	0	0
GlutamineC13-1	40255600	43755860	44403236	37700472	37094452	39278852	62730604	63436464	60632652	42290312	44213780	45403156	10387115	9600495	9245797	9508055	9698685	10607311	22000814	20525126	20120946	9105792	9154810	9527787	0	0	0
GlutamineC13-2	13360669	13479561	13732148	14746505	14582523	16300212	31263174	30376842	30173376	14886793	15194600	15644241	5765952	5297562	6141992	6014908	6530298	6189314	13090493	12053560	12081349	6584398	6362740	6174078	0	0	0
GlutamineC13-3	3372559	3811066	4175285	4222310	3930669	4693570	9411956	8519285	9135045	4421420	4106298	4303258	12926157	11963881	13014740	15200448	15861219	16619011	22031230	21051182	20107006	13830208	14102331	13543223	0	0	0
GlutamineC13-4	2589198	2747608	2879876	3604493	3358888	3724672	4503852	4048328	4643202	2741330	2928078	3079025	43301104	41063808	41577612	42437612	43522492	44112484	45641884	43147628	42167380	39502780	40894020	40213068	0	0	0
GlutamineC13-5	900859	1103038	908386	1231450	1253568	1555784	1627999	1223851	1435522	1123644	1002235	1010716	980494080	948791552	952507200	977176384	1009415872	1040993728	1044313408	988293440	981592768	949451584	948234560	962149056	0	0	0
GlutathioneC12 PARENT	49375341	49432073	50309789	64584461	72711141	73583133	50240781	53019921	55183949	65684457	66673085	69832949	22871627	20943499	21094005	25725375	24951685	28622675	30458333	31146987	28078695	21314191	24654455	24917397	0	0	0
GlutathioneC13-1	7211944	7744312	8084278	9767483	11351517	11438771	9034869	9995367	9867985	9884162	9684202	10763212	7195838	6445160	6549902	8983431	8092452	9508617	8253582	9036979	8139892	6184464	6930274	6913014	0	0	0
GlutathioneC13-2	20272406	20631574	20938934	36436316	40158508	41654452	16236811	17683132	18277778	28016646	28870192	29917978	5521300	4909234	4988380	6824712	6340646	7644766	5513872	6057606	5350116	4473018	5718854	5639788	0	0	0
GlutathioneC13-3	4214518	4488468	4674978	7169890	7862894	8205974	3769901	4376032	4132535	5001942	4972242	5573650	10846623	10035825	10440412	15833976	15907240	18296938	9204620	10354175	9552428	10648659	13110823	13283083	0	0	0
GlutathioneC13-4	3693238	3600700	3576506	7895538	9221549	10171115	2489058	2656200	2664870	4884750	4922542	5298892	2436765	2213248	2105282	3319196	3558646	3969160	1848087	1829629	1787746	2357081	3097154	2989225	0	0	0
GlutathioneC13-5	559311	455454	515700	1864164	1992409	2276673	70117	203629	212792	644739	654633	811690	32866685	29983975	30216239	49300097	49840429	55896061	23952499	24364211	22469659	39023945	43793649	44074201	0	0	0
GlutathioneC13-6	283457	301157	254905	1080556	1121496	1124822	119832	169321	211125	317103	422509	402493	1573597	1522092	1431643	2573103	2443310	2773988	1174181	1109162	1129090	1767430	2104875	2097066	0	0	0
Glutathione disulfideC12 PARENT	2602599	2518443	2324839	3290325	3280774	3064880	3148103	3135661	3338745	3679818	3797553	3829689	574601	520025	548108	428361	408268	473327	1125011	973202	1022620	603895	521199	545039	0	0	0
Glutathione disulfideC13-1	979783	835479	875132	1139087	1145580	1052014	1402378	1315008	1347183	1271277	1349787	1266175	416625	406050	374375	347485	384146	351599	727494	709587	686396	440635	392545	395979	0	0	0
Glutathione disulfideC13-10	0	0	0	0	0	0	0	0	0	0	0	0	1358893	1355648	1431026	1966576	2092813	2198786	827356	767255	740345	2136490	2044260	1996865	0	0	0
Glutathione disulfideC13-11	0	0	0	0	0	0	0	0	0	0	0	0	200714	194499	165384	246105	289661	275604	96863	102872	115780	305891	297272	270570	0	0	0
Glutathione disulfideC13-2	2225148	2074893	2013999	3808376	3743300	3644072	2356135	2289462	2418923	3332677	3612523	3414757	443494	371562	401793	365153	376509	376272	588946	546908	561101	352519	370148	387155	0	0	0
Glutathione disulfideC13-3	957453	839105	769029	1433015	1404370	1370274	970958	916233	978277	1125894	1226485	1203909	807572	739041	752144	786156	798093	875242	956548	934809	910389	801613	793147	773202	0	0	0
Glutathione disulfideC13-4	976965	847136	879696	1985284	1932263	2053907	800573	751493	740691	1209718	1332510	1481604	339956	383268	391775	438665	460962	388545	479088	450396	437393	405666	378915	407789	0	0	0
Glutathione disulfideC13-5	430827	363913	388493	848125	804447	808710	343600	334964	338504	497499	571263	510859	2148168	2083563	2176875	2271054	2439766	2511136	2243715	1976984	1904032	2634226	2596183	2559060	0	0	0
Glutathione disulfideC13-6	218724	251735	237075	703018	699287	642413	0	187250	201872	322744	368285	362482	1012509	983126	969796	1048622	1221844	1211500	930128	812996	804473	1225489	1070587	1092908	0	0	0
Glutathione disulfideC13-7	125231	109953	105682	295178	314235	286285	57660	82527	75530	128537	148596	151923	631315	582397	607354	748923	753236	795702	510145	446871	417475	740693	703626	694017	0	0	0
Glutathione disulfideC13-8	34853	40489	41652	144437	137058	171548	6246	20617	13706	64060	35733	66649	906789	912703	947009	1311665	1442520	1478343	693987	605484	613668	1325625	1236300	1220532	0	0	0
Glutathione disulfideC13-9	19391	0	6185	41340	71676	60052	0	0	0	11955	0	10746	245892	301683	277173	389497	427158	426255	155779	176231	170596	393117	409205	418122	0	0	0
GlycerolC12 PARENT	147283	156112	207453	89407	80490	76685	72386	178988	63727	236652	127510	277069	101082	216443	125185	389136	133273	332804	247859	71062	168984	107027	104619	189337	0	0	0
GlycineC12 PARENT	12476491	12429688	12675544	14563483	15099300	14689633	10248169	10082788	9601637	13381909	13816952	13381553	15864301	15091640	14637181	19324314	19688718	21114798	11577680	10399141	10924427	16581101	16675585	17053524	0	0	0
GlycineC13-1	337367	396651	364833	589180	533660	564190	289995	272949	271823	410697	424929	437659	358773	295078	316530	446906	471299	472280	257841	232820	217401	407277	392222	415742	0	0	0
GlycineC13-2	2943088	3093300	3063814	6855862	7064782	7202982	1603148	1363284	1481706	4614794	4713748	4689132	39652	45754	37103	39081	50595	51865	19624	30211	8047	31381	25726	23027	0	0	0
GlycineStd	239281	179514	237830	236681	244045	222863	237559	218444	246297	245761	234264	244251	233437	218073	207063	212622	204541	197636	231540	268507	224257	221494	237519	210008	0	0	0
GMPC12 PARENT	227750	286891	209841	260912	273057	296738	355020	330774	384104	267309	286237	243722	1293896	1022831	1077144	1939748	1631882	1556505	789882	997889	895990	1453281	1184244	1381610	0	0	0
GMPC13-1	0	23441	0	19203	0	14195	0	0	0	14413	16859	19238	42573	104266	144162	175536	206966	169491	102382	57144	111530	223909	90312	158569	0	0	0
GMPC13-4	50310	50470	88274	93270	26007	77365	18030	49086	19656	102961	83499	69892	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
GMPC13-5	776926	789281	771689	1194952	1138616	1218896	679182	695758	634272	925923	1100784	1042010	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
GMPC13-6	216691	219141	290762	1012845	826572	757382	41409	0	50106	356783	362692	389372	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
GMPC13-7	40515	80067	34806	500756	437374	460268	0	0	0	188794	134281	147633	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
GMPC13-8	0	0	0	204353	232963	149887	0	0	0	66996	50593	47037	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
GMPC13-9	0	0	0	68419	55697	53839	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
GTPC12 PARENT	180909	102107	40890	0	0	102380	330584	358781	83968	217103	120158	79533	1374825	1127329	1230798	1736774	1583260	1502594	1063040	1021329	1008448	1749694	1325200	1137728	0	0	0
GTPC13-5	263795	692505	763832	303703	325420	708384	725790	616013	216006	566384	714606	363953	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
GuanosineC12 PARENT	0	0	0	0	0	0	0	0	0	0	0	0	107163	100533	78305	110989	63641	135434	54641	50055	60483	68692	25754	64793	0	0	0
Hexose phosphateC12 PARENT	545231	465792	531510	496793	450568	558961	872413	590800	865078	534249	742773	594570	1459887	1384252	1543990	1643167	1915808	2070971	1174938	1531377	1397946	1618322	1833005	1548572	202607	0	43864
Hexose phosphateC13-5	90214	57272	47527	43450	68029	0	0	0	0	0	0	33456	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
Hexose phosphateC13-6	1649924	1361807	1858315	2539730	2127492	2045227	583222	646431	809046	1026221	1078502	1144812	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
HistidineC12 PARENT	5555726	4157893	4177064	4922040	5124570	5757726	5613646	5766466	5608642	4341974	3921328	3250047	3603824	3270390	3448552	4136496	4135437	4215556	6594342	5500876	5522874	4141997	3871049	3328097	0	0	0
HistidineStd	5288294	5249052	5481216	5348074	5569678	5573294	5415734	5854350	5418602	5479052	5563322	5327222	5811236	5882184	6280600	5429630	6008090	6186288	6488802	4961690	5455886	6070864	6221148	5841894	0	0	0
HMG-CoAC12 PARENT	1459	1459	1757	2766	789	0	632	1780	653	624	1333	0	36031	31514	34506	52793	47632	52985	17829	17887	15748	32102	29093	29494	0	0	0
HMG-CoAC13-1	0	0	0	0	0	0	0	0	0	0	0	0	13938	12419	12642	18262	20252	20260	6693	7817	6048	14023	11721	12838	0	0	0
HMG-CoAC13-10	1671	1536	664	8473	9813	7364	0	0	0	5035	5227	1387	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
HMG-CoAC13-11	770	0	567	6778	6509	6533	0	0	0	2245	1455	1203	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
HMG-CoAC13-2	1825	4178	4352	1744	3702	2869	0	2115	1306	4086	2322	2295	12233	13063	14543	21922	21368	21402	6870	5224	4149	12042	14575	14183	0	0	0
HMG-CoAC13-5	6992	10043	7465	10521	9735	5448	2870	5007	4013	5664	7373	8228	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
HMG-CoAC13-6	4842	5508	5600	7571	7610	8622	0	0	625	6480	4229	5301	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
HMG-CoAC13-7	11551	8676	10865	16277	18379	17003	3758	3212	1331	10379	11333	8992	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
HMG-CoAC13-8	2992	5033	5386	12481	10578	14014	0	0	0	5640	6342	6004	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
HMG-CoAC13-9	6191	6744	6394	15881	15902	15973	0	0	0	10186	9689	9218	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
HomocysteineC12 PARENT	48941	36058	43127	43013	91252	89487	29227	18233	15811	38301	18992	43833	39448	36922	33064	22934	55491	58767	10280	0	35877	29753	32849	38386	0	0	0
HydroxyprolineC12 PARENT	131076840	132091672	130010600	195292272	185107072	189808640	137690304	132841784	137685840	162111984	165213744	167003760	133805960	125786600	126876376	181406576	168687280	187808768	131995104	129067008	126777640	147041456	154056016	149069424	0	0	0
HypoxanthineC12 PARENT	0	17553	20239	0	0	0	218736	209545	205778	0	0	0	62251	47571	25749	0	0	0	292994	233547	216445	0	0	0	0	0	0
Inosine monophosphateC12 PARENT	0	0	0	0	0	0	0	0	0	0	0	0	99232	61625	42770	138842	190899	182832	66515	113534	89850	272751	167549	203130	0	0	0
InositolC12 PARENT	190179792	176550672	194209104	282646016	277125408	313559328	556603712	546233664	556697856	408179488	406403488	413279968	170214048	155501232	172390656	265636016	250610544	277228576	571052736	513709152	556353984	405163936	388549216	398955040	0	0	0
Isobutyryl-CoAC12 PARENT	1394	1261	716	850	1264	0	633	2246	1272	0	0	0	12385	11237	12494	22128	19927	21895	12345	13122	11018	11007	12488	10629	0	0	0
Isobutyryl-CoAC13-1	0	634	0	0	0	0	0	0	0	0	0	0	4196	2156	5082	6453	6804	8225	3340	4013	2501	2204	2353	0	0	0	0
Isobutyryl-CoAC13-2	545	710	0	0	0	0	0	0	0	0	0	0	4192	2213	2645	8538	3698	8425	4322	753	689	3084	2364	5873	0	0	0
Isobutyryl-CoAC13-5	5039	4326	4114	4037	3882	6991	1391	1395	708	0	3073	3068	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
Isobutyryl-CoAC13-6	2114	2077	1330	4194	6219	6039	0	0	1277	686	523	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
Isobutyryl-CoAC13-7	4653	5907	8467	9355	9945	11087	1761	1193	1347	1696	3789	3572	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
Isobutyryl-CoAC13-8	659	1978	576	8244	6328	8305	0	0	0	712	556	1114	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
IsoleucineC12 PARENT	67179864	51803904	51998796	69919832	67903352	76223000	51131148	50652452	50750284	57205952	60894688	54041760	52602172	50744336	50568640	65224396	65860796	68010208	53228916	46270944	47233188	55754228	58501364	52955540	0	0	0
LactateC12 PARENT	18068776	15185919	16623032	24111306	22790258	26054954	11363883	11691591	10350061	16015023	17965008	16263293	25963112	26331418	26713178	54612000	51396244	55460844	19458112	18832390	18373800	34480944	35978140	30647560	0	0	0
LactateC13-1	925754	767864	840476	1267572	1320522	1423336	648854	584299	483999	774518	830539	685145	754234	852959	1025265	2240283	2165629	1913217	651810	605645	754893	1267914	1284888	1105441	0	0	0
LactateC13-2	1531924	1320076	1488783	3205420	3170478	3597950	635685	621021	606682	1493429	1598467	1426460	208685	139957	181198	382645	397548	440858	83074	51994	24900	306240	222413	173500	0	0	0
LactateC13-3	36010644	32782278	34995372	74255400	71758176	83929544	13837064	14440805	15388829	34377648	39581956	35660204	417269	427180	393226	1321598	1284809	1248029	234371	249895	304426	730736	759340	689084	0	0	0
LeucineC12 PARENT	78887616	64007572	63020020	77889088	87866056	93186616	64964044	64418560	62430316	76079608	75719112	70439288	63726556	59124284	57133532	77737032	80261016	81200616	65995568	59386788	61562668	76283512	69295840	66535936	0	0	0
LeucineStd	18167448	18455334	16969570	17674998	18182182	19026478	17477352	18130710	18151336	18332102	17380892	17237722	19078894	18512846	16777200	18363600	17306488	16472692	18228234	17915886	18575078	18961418	18274114	18628118	0	0	0
LysineC12 PARENT	2919507	2340037	2151487	3017793	3441065	2978325	2674985	2470092	2830918	2618592	2975469	2984543	2139306	1965797	1852130	2351617	2229755	2302589	2289917	2127958	1949125	2580316	2488553	2416286	0	0	0
LysineC13-1	360909	342897	430810	395649	400345	0	0	412636	377183	454922	419342	419270	454311	553244	487177	505838	544576	462373	502999	485348	490399	551877	545115	457252	0	0	0
LysineStd	774879	751291	672517	696314	923774	705364	729376	675909	831173	707255	722492	813748	672186	716583	605273	698456	624494	613050	674484	629805	632057	672976	675795	650640	0	0	0
MalateC12 PARENT	112679904	111559904	115216792	127045704	131052648	129138952	62922692	63559188	67164176	79484968	85592680	85064928	52364164	51673868	58875520	52281296	57166796	55251040	39366344	42887048	40868736	40118892	38305808	40723980	46323716	40392380	34425108
MalateC13-1	12104606	11868316	12368485	12945934	14181349	14294468	6956732	6996913	8619155	6497673	8127832	7571043	9763622	9383140	10514761	11780033	13521782	13305421	5852905	6785634	6405224	7909692	8047077	8223838	0	0	0
MalateC13-2	22557769	22865537	24114935	33716119	35555307	36099271	11072798	11484190	11975247	16457591	18197869	18542591	13876780	14515014	15659120	20831671	22557313	22503197	7899326	8232716	8397945	14211803	13116442	13780086	0	0	0
MalateC13-3	11455731	10439239	11227813	17796968	18247118	18755780	5722982	6033626	7479122	8833611	9653283	9205290	10159577	9518773	9011347	12779459	13906580	14294613	3583185	3852102	3680429	7063748	6808674	7378356	0	0	0
MalateC13-4	1872943	2027871	2010651	3808782	4073492	4057890	738152	598094	765666	1005343	1082722	1303260	20160438	20835786	22140928	31866674	34532726	33812902	7844566	8384456	7883632	17757250	16848250	18238794	0	0	0
Malonyl-CoAC12 PARENT	501	656	0	607	1443	0	1219	1731	1920	0	0	0	4870	3240	4531	5884	5638	2954	7265	6327	5781	2888	3652	3712	0	0	0
MethionineC12 PARENT	16549269	14180999	14253333	21282562	20865290	21207278	14680304	15203683	14075708	19285818	21207502	18622038	13870829	12657020	13062536	17597192	17138522	18311734	14700880	12561473	12924096	17102842	15706115	14506499	0	0	0
MethionineC13-1	960481	819964	754274	1238081	1191085	1247512	713784	883843	769209	1072253	1124929	1017951	674662	643469	669466	951804	751708	857231	732873	665387	624625	798432	735543	748574	0	0	0
MethionineC13-4	343468	323024	353962	1029224	963047	906875	163897	174673	136050	694321	650627	649132	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
MethionineStd	9775447	9720463	9559325	9366031	9384360	8409915	9862369	9420072	9341876	9157509	9928863	9148527	9916246	9799787	10090836	8935783	9148205	8993109	10221081	9600555	9991652	9655439	9114983	9178146	0	0	0
N-AcetylglucosamineC12 PARENT	59873	58138	57068	54679	38575	57197	60729	72752	66085	40059	36842	44759	104984	99022	106819	112572	92009	99648	119198	126366	126173	100791	87844	86768	0	0	0
N-Acetylglucosamine-6-phosphateC12 PARENT	295009	391520	400538	542356	387148	434149	304657	384575	547447	438863	420656	479597	532591	710622	647879	1005878	977450	1054172	739145	818010	709522	1094894	1128000	1145102	0	0	0
N-Acetylglucosamine-6-phosphateC13-6	251105	355038	373275	483625	278798	667849	307999	355321	282371	428976	522907	421689	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
N-Acetylglucosamine-6-phosphateC13-8	71496	16730	54467	321547	367084	329747	17766	0	69309	177732	415772	431454	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
NAD+C12 PARENT	2558131	2758529	2656044	2792245	2646047	2723570	4074806	4037105	3999466	2861312	2984069	2957008	22837512	23501718	23856982	28553270	28610150	29411062	20255428	19341918	19619206	21121808	21345520	21671192	0	0	0
NAD+C13-1	714153	697707	737265	714877	690268	716444	1271546	1209824	1231353	758333	772256	742654	5961940	6107146	6275502	7398944	7392388	7771998	5182392	4893607	4920916	5394794	5527364	5391532	0	0	0
NAD+C13-10	9096664	9533984	9633064	11836252	11889843	12398937	5271610	5269960	4946466	8675068	8887887	9002086	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
NAD+C13-11	2026205	2129859	2159777	5101832	5191068	5603550	966238	900410	943426	2532373	2609313	2640373	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
NAD+C13-12	720377	750068	778615	2470414	2568376	2749147	295001	235896	234324	873417	1059023	1114723	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
NAD+C13-13	194164	194694	232538	1185347	1145411	1246968	50198	0	44306	363848	377923	427495	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
NAD+C13-14	11257	32591	10982	371799	320936	320706	0	0	0	97240	89803	91109	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
NAD+C13-2	503453	541879	589511	405833	447306	454109	1126516	1019304	983885	475626	461519	473447	1438896	1565069	1545182	1698304	1768985	1860751	1290284	1222857	1144416	1196345	1324900	1336889	0	0	0
NAD+C13-3	302713	278636	295546	223261	232834	226160	583493	517973	496126	252522	239061	275685	437451	376185	425068	405585	410000	441608	322886	350578	349647	317539	298702	275486	0	0	0
NAD+C13-4	641943	635339	677996	581601	545784	488497	1036892	935708	1026209	570626	576570	554042	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
NAD+C13-5	5932376	5997642	6068098	5828950	5960838	6215920	7286598	7161408	6813958	5544556	5719586	5694170	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
NAD+C13-6	1377671	1480544	1413038	1495838	1546905	1533897	1699280	1692371	1594124	1276568	1242945	1330733	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
NAD+C13-7	1389576	1371144	1354766	1390578	1424000	1433090	1143381	1073778	1079915	1009329	1082322	933508	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
NAD+C13-8	805779	852551	842432	1166457	1068905	1146155	539255	584730	544073	758853	695841	761066	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
NAD+C13-9	1648786	1660123	1684908	2244617	2128578	2177697	1049420	1067853	1026056	1478974	1534363	1528606	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
NADHC12 PARENT	168347	174825	215030	268874	223931	192552	373206	317865	409870	274457	328557	349013	1240858	1299343	1501000	2285438	2119258	2143914	1481779	1718502	1463106	1681944	1556127	2092814	0	0	0
NADHC13-1	37032	53073	46064	42814	43030	49403	101312	120196	119031	72852	88733	96763	355573	315149	373077	619318	536280	563299	379037	436356	368127	405570	395050	544406	0	0	0
NADHC13-10	562292	637806	700911	1027542	1018432	856360	472821	442750	489606	807869	1035033	1069462	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
NADHC13-11	131983	127620	145990	436175	436002	377494	67098	69922	76059	235113	286431	330637	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
NADHC13-12	31535	32048	45588	202418	235248	196469	8140	21071	24795	101681	111280	130033	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
NADHC13-13	0	0	0	90084	93589	60836	0	0	0	34941	30571	26224	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
NADHC13-2	13126	14529	11039	30556	30372	23371	74394	105076	100532	30473	54860	33100	75961	46814	63952	106523	111464	112128	71540	76093	87105	101310	77580	101080	0	0	0
NADHC13-3	17375	9149	16753	20139	6230	13909	47312	32865	51442	10223	25114	25680	17333	5871	0	26803	13038	12620	19180	22332	15537	19647	13063	21227	0	0	0
NADHC13-4	41483	43078	64434	32254	45670	36842	94436	82859	89290	53165	69149	62409	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
NADHC13-5	356989	358756	406666	491890	544667	455030	549049	583832	684911	508311	616766	657310	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
NADHC13-6	69933	88029	99861	138993	129870	98479	117418	138886	158762	121447	124863	168095	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
NADHC13-7	66230	93874	66841	99882	77286	91149	64149	92086	106757	103430	108326	126041	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
NADHC13-8	39393	51494	45361	81328	77965	61029	36246	33491	34550	63301	58882	68700	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
NADHC13-9	99308	112691	130772	182917	166259	151940	68568	82571	110052	143099	172575	197792	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
NADP+C12 PARENT	185049	169992	163371	189355	183108	205783	246189	242926	236929	180347	191474	169034	1483951	1477918	1418191	1886916	1885295	2125631	1178915	1035802	1059981	1351351	1466079	1235472	0	0	0
NADP+C13-1	52993	46168	45630	55575	50864	55151	81323	72310	73756	50297	46480	48743	406617	396433	376771	476861	507838	561382	311584	278049	281333	370381	382983	320299	0	0	0
NADP+C13-10	600793	577927	548016	769492	785600	879763	309174	302170	299782	547175	538890	512232	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
NADP+C13-11	135464	127028	123533	314620	335231	388925	51949	50636	56189	155496	149687	150314	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
NADP+C13-12	45564	43605	44165	169217	157705	182354	16242	16065	16629	66262	70216	63701	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
NADP+C13-13	11064	11828	11703	81437	72260	91149	2434	1531	5474	24297	19307	27696	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
NADP+C13-14	2921	2123	1664	27637	25557	25376	0	0	0	7209	6836	3090	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
NADP+C13-2	33812	31579	32641	27949	27426	30477	67063	65378	63564	32953	27177	28203	104969	109989	98458	135605	132836	149302	83565	82545	78005	93939	98036	88603	0	0	0
NADP+C13-3	21957	19786	18250	14403	18741	17299	31555	26757	27462	16586	13942	16873	28721	28512	26781	30917	36374	28881	23023	20621	21453	21684	21860	18865	0	0	0
NADP+C13-4	46498	34473	36520	37053	35113	44909	55821	53860	57557	37365	34290	31051	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
NADP+C13-5	409180	361210	346595	403643	370940	449246	413160	414540	412724	362393	349284	342808	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
NADP+C13-6	98029	87045	91295	105178	108169	122572	98105	98845	98950	79987	83711	80323	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
NADP+C13-7	92743	82349	75458	82579	88380	103560	62950	59696	71347	70654	60203	63928	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
NADP+C13-8	51074	54218	49187	77210	70252	81148	32707	35218	31103	48180	46212	46864	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
NADP+C13-9	112316	101955	99536	137067	143546	155148	63208	60720	59637	102241	95125	89679	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
NADPHC12 PARENT	13270	18745	24499	23578	21622	9971	53631	53044	57913	35084	37740	41193	164800	139560	170751	256862	181653	203437	204111	244210	217086	179697	159017	220903	0	0	0
NADPHC13-1	2866	5309	6275	5733	4700	0	16289	16708	19270	9348	12178	13438	42672	37811	45627	73233	55048	50418	52844	54669	56712	45135	43388	53244	0	0	0
NADPHC13-10	42164	68374	83487	93732	78109	35350	55286	62800	59931	87995	98441	117947	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
NADPHC13-11	11578	14188	20122	41924	33207	15483	14394	10070	11509	26730	26191	31128	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
NADPHC13-12	4453	4147	7762	19538	15321	9000	2557	3119	3484	10474	9274	12237	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
NADPHC13-13	0	0	0	10121	8812	2048	0	0	0	2308	2692	6675	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
NADPHC13-2	2518	3536	4523	2683	2769	0	15404	14880	15339	4815	5546	5846	11540	10786	11315	20216	11304	14627	12911	17178	11462	11560	9940	14119	0	0	0
NADPHC13-4	2275	4684	5476	2860	2972	1296	11556	11317	14510	6967	6864	7194	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
NADPHC13-5	31746	45779	54760	49835	40110	18477	87135	85488	92860	64457	67734	72981	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
NADPHC13-6	6926	12294	13389	12638	12139	6122	19417	18946	22171	15270	17229	17294	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
NADPHC13-7	6192	10855	12226	10855	8125	3001	15091	13258	12509	11235	11892	15459	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
NADPHC13-8	3093	5145	7962	7324	9161	3793	6916	7132	8102	7798	8354	11351	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
NADPHC13-9	10079	14631	14323	13687	13356	7353	14709	12661	12727	16268	16497	21006	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
NorvalineStd	39719477	41151685	39914133	41075705	37749465	40090417	40902201	40579633	40994481	41850485	41077529	41274829	44042201	39570005	41385769	42344953	39832417	42237517	44410833	41049153	41288145	42176913	38462917	39519737	0	0	0
OrnithineC12 PARENT	1739430	1541668	1456275	1632756	1728077	1567660	2095899	2042217	2152927	1566361	1625786	1613757	1396112	1183894	1213685	1172578	1095702	1166114	1402867	1435577	1398662	1266142	1153493	1198673	0	0	0
OrotidineC12 PARENT	434457	479986	545571	857137	826390	784590	387512	392222	364897	551911	641354	557724	1013065	1110600	1014996	1647573	1715935	1668165	603259	645748	593387	1131529	1144921	1099678	0	0	0
OrotidineC13-1	27858	30532	17713	20273	56233	73820	0	14157	21950	38470	25809	27114	267879	219331	258172	354861	451933	457814	152882	140491	82481	235253	274815	242271	0	0	0
OrotidineC13-2	17107	26375	35051	66413	50084	95722	12194	11873	0	20165	40076	45847	297687	257384	270040	446041	470930	562045	100147	49572	54735	274865	361390	284298	0	0	0
OrotidineC13-3	12742	48161	0	80836	38547	19483	0	14404	16062	27881	15256	0	249078	217108	167638	392033	385394	425940	67728	19711	51648	282177	292340	250837	0	0	0
OrotidineC13-4	97461	72563	53233	158258	171156	226483	15427	20695	0	95579	100186	86673	456697	532214	563959	1190034	1164723	1212120	143768	95425	98726	702104	729633	682864	0	0	0
OrotidineC13-5	1039198	1118839	1346490	2286400	2281325	2379320	430968	382091	322431	1434888	1515744	1299424	0	25745	12588	23555	113849	63591	14094	0	0	37697	17909	48821	0	0	0
OrotidineC13-6	196889	227022	144495	415118	372533	320406	16249	34347	35317	158498	101294	206012	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
OrotidineC13-7	145182	268747	237529	628855	504083	581914	47958	39044	42457	219053	253824	243157	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
OrotidineC13-8	61674	77802	59803	272928	267751	256328	18564	0	21009	55182	39242	77510	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
PalmitateC12 PARENT	254402917	166860693	125507677	184686485	130284021	181280549	255289029	203108245	156354037	353784373	190910277	184981189	261161349	242915349	146262853	242503749	154218197	150377285	219270501	134935461	127972877	405174965	232238341	136408341	0	0	0
PantothenateC12 PARENT	121118136	120796800	114400408	203687296	208413616	207914672	109724440	99201304	107985048	157889296	188673728	185705520	116919416	90753952	104899544	176582640	147991968	174267792	96541608	99641304	95635688	145462400	156985728	158763648	0	0	0
PhenylalanineC12 PARENT	32981400	27089450	25408974	29217968	33151786	34463168	28028522	26973520	26140624	28533294	29085242	25984128	29397576	27059568	24979838	31700072	32734074	35639104	27904670	28314582	27911688	31778310	28352070	26767854	0	0	0
PhenylalanineStd	26056826	25553274	23312738	24303046	24338082	24247298	25713056	25970474	25098458	24698170	25039518	23601728	25889834	25637008	23256160	23960914	22159166	25465504	24053666	25595160	24944654	24942816	24778398	23222048	0	0	0
PhosphateC12 PARENT	4895642	3340560	3175926	4492474	4722834	6017284	3344628	3521762	3233612	4478234	4059154	3397726	3573148	3428121	3223600	4840882	4867392	5161982	3231636	2822643	3082394	4292666	4268386	3718180	0	0	0
PhosphocholineC12 PARENT	131782449	135220113	137125665	194449825	185220801	190369953	84520745	83223249	78514009	128490409	136014913	124741049	146633537	140589489	138784017	170104401	166963009	192163617	85980617	78856785	80879153	111206833	122228433	124134825	0	0	0
PhosphocreatineC12 PARENT	119833384	135350240	138864080	176454800	222202240	210566656	157387776	147768144	150567568	195627696	181461648	183097472	155339216	145220736	153096720	190471344	191467728	228257360	158926576	169488880	172249808	188158672	185603008	178698992	0	0	0
PhosphoenolpyruvateC12 PARENT	15921	37785	0	236865	107584	171494	30199	0	58111	132798	109921	64581	333055	287944	272607	566468	774916	713614	329915	330438	414308	490387	622134	501465	0	0	0
PhosphoenolpyruvateC13-3	477935	396086	529237	1141344	918008	1255233	388606	300493	316353	512741	664991	529328	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
PhosphoethanolamineC12 PARENT	639664	580987	535446	88781	109502	132896	2902500	2984595	2797917	280358	274634	238944	1086919	939389	909386	241032	268613	273877	4312158	4112850	3883473	286610	353630	371629	0	0	0
Phosphoribosyl pyrophosphateC12 PARENT	0	0	0	0	0	0	0	0	0	0	0	0	117282	129664	175042	371099	380215	390940	50844	127252	91642	390728	440078	450511	0	0	0
PhosphoserineC12 PARENT	541381	657868	645331	497914	449636	475684	480727	398121	466760	432936	610224	414866	896988	802819	879811	1405899	1465890	1237557	606426	738383	926341	792077	847111	691735	0	0	0
PhosphoserineC13-3	45626	179487	195740	272251	168198	294591	43857	87171	149673	88653	131325	141763	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
ProlineC12 PARENT	89933440	88343176	90119104	166975760	170504848	179528592	72082504	70748360	73554544	149711408	153116272	146997776	71566688	64946420	65407420	103522200	101443328	116844280	63068548	56883412	61418768	97342496	92855200	87771560	0	0	0
ProlineC13-1	7383192	7033664	7382582	13002557	13207181	14012479	6419790	6243890	6411628	11673852	11880632	11653253	8668204	7777918	8153010	13734289	13470200	15670632	7511828	7027278	7628916	12197351	11772493	11247875	0	0	0
ProlineC13-2	11651652	11100713	11870671	27606230	27823682	29536902	8512525	8036842	8622671	21183850	21442250	20942616	5097650	4892428	4877756	9061163	9051226	10530498	4011498	3900851	3966535	8298402	7980152	7571410	0	0	0
ProlineC13-3	2908027	2620414	2805395	7059612	7348896	7776072	1935449	2079775	2088268	4548104	4506572	4714446	11680889	10561997	10694916	22232594	22090858	25527602	7139376	7529282	8097238	19960714	19709630	18541550	0	0	0
ProlineC13-4	1955045	1879009	1963235	6027326	6213846	6601696	1044109	1075242	1034509	3348426	3298648	3380543	1868694	1805633	1754326	3704194	3931469	4561626	1117655	1068643	1137150	3774791	3622747	3489951	0	0	0
ProlineC13-5	679371	660378	727879	2216529	2136828	2387638	379452	365521	396670	1098952	1061726	1038828	32151674	29525648	29598352	64398508	64093300	74005888	18346406	17699002	18757272	62893556	60918000	57355740	0	0	0
ProlineStd	8829577	8996657	9072989	8463612	8924253	8947349	8693896	8912657	8532853	9296071	9270323	8954910	10291315	9736853	9420720	8890155	9258395	9604953	9264673	9391571	9494081	10152281	9899253	9278519	0	0	0
Propanoyl-CoAC12 PARENT	0	0	0	0	0	0	767	1125	771	0	0	0	5588	3586	4801	2342	4682	2238	6976	5793	6240	2980	4731	2545	0	0	0
Ribose-5-phosphateC12 PARENT	0	0	0	0	0	0	0	0	0	0	0	0	0	0	55601	201451	81889	119935	0	43837	29069	36569	52703	46917	0	0	0
Ribose-5-phosphateC13-5	32824	32138	56521	235918	121725	117200	0	0	0	55080	49957	40565	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
S-Adenosyl-L-methionineC12 PARENT	1097482	1014239	977550	1200440	1266833	1112088	2334964	2278714	2204369	1397412	1452936	1522035	3959231	3666938	3649973	6419026	6016708	6328882	4788621	4622368	4510910	6446248	6323828	6186930	0	0	0
S-Adenosyl-L-methionineC13-1	188130	228598	179161	218260	240314	230111	418767	392646	387192	265349	259578	283004	658996	644365	630933	1086806	1032259	1049038	705800	778987	719550	1059536	1035621	1000483	0	0	0
S-Adenosyl-L-methionineC13-10	0	0	0	115690	95909	145212	0	0	0	37117	44428	37328	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
S-Adenosyl-L-methionineC13-2	163372	165642	161604	164771	158589	170790	236410	219044	235614	186085	188401	193463	66526	43185	41034	118068	87507	97611	48344	80125	52187	84803	61119	110766	0	0	0
S-Adenosyl-L-methionineC13-3	121597	107952	109792	208919	191640	185879	131876	110582	97680	164228	169879	167454	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
S-Adenosyl-L-methionineC13-4	298621	314646	273117	440587	483925	427115	293417	270075	261485	377684	340766	425468	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
S-Adenosyl-L-methionineC13-5	2902001	2904886	2854092	3988354	4236414	3836637	2788411	2771401	2831942	4160639	4230142	4118338	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
S-Adenosyl-L-methionineC13-6	790984	703762	748049	2491351	2614182	2392588	437793	401822	405794	1477089	1592083	1550689	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
S-Adenosyl-L-methionineC13-7	230385	234653	232643	1341949	1354828	1326058	57785	61425	45715	620071	602419	659694	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
S-Adenosyl-L-methionineC13-8	91503	94787	114330	702495	722076	654216	14555	10557	0	276636	270175	281990	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
S-Adenosyl-L-methionineC13-9	86551	62456	101118	337299	348475	384252	16893	19663	16927	165218	195739	156884	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
SarcosineC12 PARENT	1979720	2174148	2143535	1956785	1892866	2005139	787948	752484	804790	871768	881444	788220	2748912	2655593	2579840	2762542	2718229	2787089	1090044	1136958	1129358	1445712	1354944	1328046	0	0	0
SarcosineC13-2	226384	221981	204094	290242	317229	316210	14234	24326	17770	48728	47933	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
Sedoheptulose-7-phosphateC12 PARENT	0	0	0	0	0	0	0	0	0	0	0	0	126357	87164	82536	328079	411710	351524	0	0	35011	120174	136885	132682	0	0	0
Sedoheptulose-7-phosphateC13-7	66805	60820	56576	394593	285355	160430	0	0	0	112301	217211	122033	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
SerineC12 PARENT	68726616	69969640	69835832	69319736	68151208	70276632	82551592	82273672	82218536	69299544	71873768	71288312	104418336	99043008	98212160	131030872	129410560	140687936	99541736	93965224	95290944	106932256	113685728	109165416	0	0	0
SerineC13-1	12217847	12283113	12649121	27220086	26580518	28658136	12566461	12636076	13101315	21169986	21820296	22212256	3904099	3716031	3585618	4936428	4890004	5102484	3520990	3689334	3490240	3882913	4111871	4277574	0	0	0
SerineC13-2	5843970	6211366	6269652	16294752	15914973	16366219	6478320	6051568	5607042	12202125	12693584	13184415	168319	156221	112793	254480	165139	194693	97998	169587	175012	190825	157525	146536	0	0	0
SerineC13-3	21401376	22834786	22298894	39849440	39172992	40214056	13211568	12569408	13024360	23838094	25179598	25427502	329732	252311	280036	237322	235312	306494	172069	196911	299634	145140	178437	163523	0	0	0
SerineStd	2773524	2828693	2830439	2765392	2613089	2804549	2952843	2599163	3097099	2928642	2755524	3016043	2903902	2781022	2800509	2603371	2509238	2598524	2530545	2801134	2941955	2625344	2942509	2804212	0	0	0
SorbitolC12 PARENT	20837578	14212900	13660993	17874384	18173386	22052992	11611451	10832614	11447019	13659721	13566336	11275201	11440765	9916153	9855730	15874123	15162687	15475639	10476601	8913773	8936577	13648799	12295189	9962788	0	0	0
SorbitolC13-1	1423990	980757	885316	1129802	1117073	1458338	688983	705325	733256	973060	893191	681858	761536	620413	581358	928938	1000491	876599	705320	532286	486917	797410	877061	610793	0	0	0
SorbitolC13-6	384534	405681	418514	493072	575770	530351	369287	374346	411734	389294	464354	491393	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
SuccinateC12 PARENT	10952149	12682513	13048231	10543555	11153100	11401208	8254260	9100217	9333059	10644447	9836581	8791113	8722687	8929206	9331183	8569704	8745629	9891469	7851172	8525346	7563978	8526379	8631559	7751430	9135097	8170916	8604712
SuccinateC13-2	941701	851076	857286	1797217	1249277	1718327	554533	668857	636463	996320	873939	763042	804318	586750	585712	1503501	1293960	1306111	435570	455862	357865	739315	643622	744798	0	0	0
SuccinateC13-3	134158	258606	262016	737930	537674	677367	62205	139360	94652	143575	140795	143679	50545	81901	70743	0	39004	0	0	0	0	34207	0	32126	0	0	0
SuccinateC13-4	67925	93734	80801	218154	287384	185603	0	0	18309	0	37985	0	1632982	1407746	1680910	2565498	2045190	2571841	643338	631869	578263	1097621	966694	1145936	0	0	0
Succinyl-CoAC12 PARENT	18496	14950	15732	14094	14650	11300	23630	20693	24499	12035	12390	14251	38078	25767	32566	38776	34455	38071	33187	37750	35370	25780	26108	26978	0	0	0
Succinyl-CoAC13-1	7815	6807	6516	6209	6790	5788	12737	12132	12364	6773	6744	8197	22815	17260	22369	27824	25290	26243	19710	23058	19274	18448	20271	22461	0	0	0
Succinyl-CoAC13-2	9404	10918	9013	9411	11395	7786	11079	11193	13209	7862	9206	7192	20809	19125	25392	35098	29335	32116	17161	18671	17074	21493	24411	23554	0	0	0
Succinyl-CoAC13-3	6491	6657	8212	8196	8877	6881	8856	7245	8345	3594	6582	6341	10130	9513	8310	14277	12271	13221	7732	5969	5811	6911	9709	8193	0	0	0
Succinyl-CoAC13-4	9141	5368	7270	10278	8519	8366	7160	5909	6452	4886	7538	7138	34101	22696	32495	59271	47241	56020	18995	17254	20702	28729	32309	34218	0	0	0
Succinyl-CoAC13-5	50169	47789	42148	52132	57337	43674	31381	26152	31480	34726	42947	46531	10429	8367	7160	15587	12055	16348	3609	5188	3338	7591	8753	10675	0	0	0
Succinyl-CoAC13-6	25201	26373	25306	41219	42577	34574	14156	12123	14993	19074	23679	29852	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
Succinyl-CoAC13-7	23139	21424	23187	42914	48055	35222	11168	11168	13164	21424	23922	26074	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
Succinyl-CoAC13-8	13512	7428	11920	31627	34672	30319	5837	5962	8288	14146	13708	13816	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
Succinyl-CoAC13-9	5278	6628	7222	17097	19843	17866	1424	655	1441	7670	5569	7767	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
ThiosulfateC12 PARENT	275428	260658	252879	483468	442834	286422	158071	129299	89060	321219	335661	242050	150141	292914	213496	407214	260317	348915	105555	55110	90660	208881	117502	219362	77618	28776	17638
ThreonineC12 PARENT	27404930	26828248	26366922	35435812	38566452	39374772	24041758	25255574	24083534	30470944	33262688	30270498	25466698	23771874	23762432	34345632	32881424	33727800	21011742	20111354	20643878	28230802	29016202	27363034	0	0	0
ThreonineStd	2051804	2062394	1945906	1963960	1990913	1863010	1882234	2039187	1848532	1777007	2062079	1916310	1867447	1927547	1773229	1891643	2073802	1809909	1918487	1847474	2018673	1752258	1885142	1894920	0	0	0
TryptophanC12 PARENT	5895668	5213292	5196606	6866722	6088724	6978608	5023364	4819744	4415806	4785582	5161122	4278366	5134078	4754136	4800452	6190964	5466414	5708898	5500860	4954114	5179850	5040256	5050562	4602284	0	0	0
TyrosineC12 PARENT	16067243	12552624	13028859	16711983	16886058	16813710	12283491	12552007	11654872	11078632	11494659	10583385	12283545	12073764	11850803	15212848	15993357	16294816	12862388	11653244	11717179	11578253	11524432	11290136	0	0	0
TyrosineStd	10756958	10171020	10772116	10163900	9848603	9763393	10778809	10972861	9473327	10194649	10599559	10082461	10392465	10747548	10076918	9624927	10877336	10135923	10666964	9614311	10220769	9794145	10209255	10759379	0	0	0
UDPC12 PARENT	912876	821339	1002746	1141304	967725	1029254	2296729	1953912	2358919	1472148	1381036	1296577	1990532	2032604	1946325	3026548	3008755	3023618	3168072	2881534	3255549	3211555	3120880	3140233	0	0	0
UDPC13-1	132405	67675	133904	89593	96886	109884	320061	238220	291426	105105	126025	69158	601458	400774	607797	986201	1044474	1151909	560152	516138	534941	1050325	899136	1046344	0	0	0
UDPC13-2	38490	0	48873	73338	87825	139582	0	50056	55832	95088	91784	39724	382662	437348	425467	754579	851366	875204	240494	260395	297008	830103	878248	837626	0	0	0
UDPC13-3	20654	0	0	34212	40938	55595	18392	21138	18140	101544	139046	78125	994972	864784	878417	1915073	2332627	2395480	540713	518422	472810	2254745	2356130	2244881	0	0	0
UDPC13-4	154764	68014	187442	385241	162835	424558	92640	56446	64618	365536	353382	319812	26375	21073	43034	97581	161200	137054	0	0	0	103584	182654	145076	0	0	0
UDPC13-5	1737980	1496300	1592398	4640880	4092163	4130382	1046600	1068725	916677	3983563	3979050	3963059	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
UDPC13-6	268179	335475	340710	1004481	1007681	1066572	228653	207544	237405	714463	833337	903245	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
UDPC13-7	207791	201924	227929	1075610	992174	951694	164479	150770	170149	566762	638493	573198	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
UDPC13-8	0	0	78961	328300	218858	293624	0	0	0	82978	127423	169310	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
UDP-glucoseC12 PARENT	0	0	0	0	0	0	137885	130211	93137	0	0	0	5359523	6054288	4536702	4826048	4902786	5864080	5233414	4781688	5738888	3379720	3434776	3891788	0	0	0
UDP-glucoseC13-1	0	0	0	0	0	0	0	0	0	0	0	0	1841378	1444870	2191520	2221907	2235502	2677148	1405300	1446912	1311112	1554573	1307219	1302668	0	0	0
UDP-glucoseC13-10	632806	702509	837758	1235651	1276976	1281727	708519	535005	354755	881423	911918	699546	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
UDP-glucoseC13-11	4166293	4443376	4205386	8259004	6541516	6777796	2398752	2076359	2252230	5687892	5041580	5707084	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
UDP-glucoseC13-12	830420	918194	1160606	1323370	2133394	1671136	600070	501182	588233	1299425	1306143	1034672	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
UDP-glucoseC13-13	900976	1009656	687981	1674368	1379921	1853728	212030	293023	408982	1095984	961539	821063	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
UDP-glucoseC13-14	177044	177357	349733	434371	330036	656642	58932	77639	24652	144310	375363	156093	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
UDP-glucoseC13-2	0	0	0	0	0	0	105441	0	59463	0	0	0	1388854	953972	1131909	1521850	2168700	2158882	869689	503861	609145	1188868	1332980	1351293	0	0	0
UDP-glucoseC13-3	97464	88871	135332	0	0	0	524194	433756	445746	36018	0	95191	2593680	2588384	2244838	3274152	4280226	4464480	1173723	992476	813337	2537656	2704998	2599204	0	0	0
UDP-glucoseC13-4	0	45131	0	0	0	0	66853	124741	160337	0	0	0	325909	440220	369349	707644	768973	682590	37807	0	60754	479786	419774	274302	0	0	0
UDP-glucoseC13-5	343138	361462	374345	262159	417473	491352	599744	611026	810006	416597	376050	295154	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
UDP-glucoseC13-6	2893230	3031933	2501324	2464963	2001514	1927716	5519210	4821242	4790284	2084494	1989178	1920302	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
UDP-glucoseC13-7	371342	354982	409751	415925	202197	236867	565448	599318	617617	361938	341056	179483	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
UDP-glucoseC13-8	350223	574240	741102	531742	483531	595410	443849	417806	406971	486855	315017	429911	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
UDP-glucoseC13-9	258305	122310	171738	364090	426046	309590	122823	201593	132302	246179	332211	295242	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
UDP-N-acetylglucosamineC12 PARENT	69428880	73585560	73326880	63897728	60776052	63234212	59567316	55677264	49580848	38255740	44497024	41655388	139580112	153706448	152003376	159854224	161055952	182573328	100781632	92779160	94820992	92682616	94068344	89058656	0	0	0
UDP-N-acetylglucosamineC13-1	13902127	14961163	14413349	13412533	12845215	13135957	11444009	9989271	10251935	8031746	9073791	8380472	42651940	44210748	46799972	58754768	59706544	68050024	25411648	22535986	23334520	29433688	28444450	27427418	0	0	0
UDP-N-acetylglucosamineC13-10	9406084	9602193	10101285	15876581	15074175	15538351	3228829	3221350	3268296	7732946	8366878	8114446	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
UDP-N-acetylglucosamineC13-11	37078364	39442936	39951756	66692416	61935508	67293688	12225964	10746831	11342915	32614026	37787252	36972896	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
UDP-N-acetylglucosamineC13-12	12320837	13043261	13779681	27960158	26968078	27960234	3579952	3208517	3355490	10713169	12433077	12040933	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
UDP-N-acetylglucosamineC13-13	21433046	23774216	25264616	64209796	60510276	64832892	4924370	5229860	5428630	26117728	26364722	25365154	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
UDP-N-acetylglucosamineC13-14	5582986	6350676	6346472	15274371	16791166	17197250	959936	946330	1409235	5455966	6323758	5937374	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
UDP-N-acetylglucosamineC13-15	3071206	3691514	3824405	11233704	10836577	11578012	681462	439672	565810	3026770	3445564	3918186	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
UDP-N-acetylglucosamineC13-16	922514	885169	1067629	3165542	3378601	3364871	106216	41528	59515	1085866	876055	1087243	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
UDP-N-acetylglucosamineC13-17	0	34769	95556	381488	241062	322746	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
UDP-N-acetylglucosamineC13-2	8261722	8701165	8831172	8319534	8005554	8263112	6055488	5846172	5519126	4413028	5273110	4959409	34349992	36059444	37579996	52638292	47990500	60212748	15317179	13902445	14874983	25979414	26742950	25193560	0	0	0
UDP-N-acetylglucosamineC13-3	5499136	5586942	5041622	4846346	4055666	5048220	4544026	4349216	4181674	2714750	2713219	2732113	42406052	47381460	49323012	90691992	92909656	105188200	9940620	11827948	12765989	40790964	41937124	39290032	0	0	0
UDP-N-acetylglucosamineC13-4	6132742	6554252	6953286	7623108	8254898	8446181	3326491	3248095	3236633	2938596	3317796	3745553	10206659	10213689	10342995	19103190	19004994	22741886	2724197	2449238	2459760	8871304	8619399	8546434	0	0	0
UDP-N-acetylglucosamineC13-5	52312240	55596748	56921356	81471832	79458312	81217144	18210106	16698168	17025474	29417472	35305392	33531274	4961024	5672288	5948280	11774564	11333368	12035605	1390420	1271956	1047916	5657828	6183114	5996794	0	0	0
UDP-N-acetylglucosamineC13-6	53290320	59012900	58935696	52533068	56048048	55627088	43255028	39493244	36597168	31766544	37350148	35487556	1127948	1215192	1202763	2254742	2320252	2526639	277514	285777	210475	1062511	1127866	909820	0	0	0
UDP-N-acetylglucosamineC13-7	19410428	20860614	21642104	26383568	26942890	29234698	9600935	7640726	8496747	12540283	13138953	12851805	249726	118350	225782	213313	523132	580617	0	0	0	95312	176316	301131	0	0	0
UDP-N-acetylglucosamineC13-8	25085526	26666106	28182186	35941120	34693604	35546836	14790461	13774956	13946897	16762565	19584864	19260844	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
UDP-N-acetylglucosamineC13-9	5709958	6428442	6601516	8190084	8538885	9195481	2909178	2693241	2516931	4479680	4841084	4409546	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
UMPC12 PARENT	747585	897150	776510	826249	814615	852430	1079383	971414	865511	561033	726764	752679	1010342	1383483	1266396	1109334	1200419	1677064	1126715	1157345	1156686	1158310	1025676	952505	0	0	0
UMPC13-1	31865	0	79629	0	0	0	111848	23215	0	0	0	0	103966	189958	249734	294943	397072	301662	40480	200180	103510	218692	199364	210128	0	0	0
UMPC13-2	0	0	0	0	0	0	0	0	0	0	0	0	108607	105467	94259	262566	272237	147852	37242	37309	41830	234040	122186	177573	0	0	0
UMPC13-3	0	0	0	0	0	0	0	0	0	0	0	0	422586	192969	245881	605348	594637	670105	73061	62723	61736	640364	515631	484257	0	0	0
UMPC13-5	373529	461622	797883	976795	2096579	1812073	178898	73701	567133	0	970841	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
UMPC13-6	0	44667	0	254770	132366	203263	0	31805	25192	253034	167010	306479	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
UMPC13-7	46364	34935	45462	81491	89543	0	0	22171	0	106197	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
UracilC12 PARENT	1593803	1163359	1307668	2239076	2042527	2379600	1638590	1392097	1573471	1690777	1929168	1595438	1797180	1718888	1791363	2572542	2214533	2676170	1995682	1772269	1709864	2130293	1972637	2085801	0	0	0
Uric acidC12 PARENT	623966	314862	424416	755671	702477	918988	746346	685905	709866	1580995	1611949	1531496	338385	306149	381896	943182	890388	853809	918926	807315	973042	2371557	2392335	2229026	0	0	0
UridineC12 PARENT	40392	74124	56489	83858	24438	43540	306966	283599	224384	54941	39469	92163	155482	161442	57958	47358	105623	95490	385996	405907	350196	155883	72296	180240	0	0	0
UTPC12 PARENT	1697833	1821661	1779635	1621737	1397465	1516522	3860753	3806020	3761393	1922851	2068862	1935893	4365370	4344004	4518798	5416125	5546334	5723640	6728256	6160776	6364670	5454096	5730352	5413938	0	0	0
UTPC13-1	296217	203901	173809	89051	142259	136422	408998	295546	259188	203392	176415	132498	1093959	1026698	1125987	1719480	2085048	2167093	1244235	1098472	1114433	1705951	1802930	1705696	0	0	0
UTPC13-2	87118	55399	245028	179201	209435	257203	208112	234299	277880	352080	206865	268239	882104	856883	992463	1711908	1731616	1754149	699172	644788	734233	1510410	1527946	1549096	0	0	0
UTPC13-3	18747	71936	120572	166594	59912	168237	82757	52716	52310	217118	148143	123267	2019718	1929954	2269166	4112602	4373469	4453320	1095055	1072687	1086806	4017432	4132599	3940838	0	0	0
UTPC13-4	308169	299935	253370	458144	550604	568651	264611	153725	142594	535962	562975	452566	141945	119393	119993	302466	375797	444913	55562	58092	66988	325289	408210	365973	0	0	0
UTPC13-5	2800799	2955712	2936275	5866722	5428908	5747782	1847740	1711019	1983760	5466188	5887326	5589846	24387	69374	18912	76828	106060	99230	21122	0	0	58953	33758	121744	0	0	0
UTPC13-6	623894	557890	588098	1401607	1200858	1551108	307698	336732	239708	1101740	1029098	965536	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
UTPC13-7	443132	441614	481997	1383878	1200197	1470418	351785	271179	263010	921102	1145376	926542	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
UTPC13-8	153020	193831	116738	401661	405255	504364	33982	80052	80238	312127	226692	237185	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
ValineC12 PARENT	9689155	8169182	6969316	8126961	8878377	7897538	8525679	7559930	8645851	6571148	7782853	7001814	8554174	7640083	7654627	8811587	8156356	8719710	8795073	8608371	8269014	8964026	8858741	7824630	0	0	0
ValineStd	4170158	4068699	3929157	3637105	3925037	3360230	4893895	4418584	4364698	3861855	4225872	4223701	4592676	4225760	4438574	4014154	4057862	3778434	4609894	4317142	4463321	4562750	4674248	4250623	0	0	0
XanthineC12 PARENT	3321046	2845212	3015188	4342518	3994771	4938804	2382923	2477561	2307440	2743334	2933758	2535654	2453864	2353758	2237794	3226197	3492985	3639032	2624135	2359613	2269874	3081553	2931537	2639941	0	0	0
MS_METABOLITE_DATA_END
#METABOLITES
METABOLITES_START
metabolite_name	KEGG.ID
2-AminobutyrateC12 PARENT	C02356
2-HGC12 PARENT	C02630
2-HGC13-2	C02630
2-HGC13-3	C02630
2-HGC13-5	C02630
3-PhosphoglycerateC12 PARENT	C00197
3-PhosphoglycerateC13-2	C00197
3-PhosphoglycerateC13-3	C00197
4-HydroxyphenyllactateC12 PARENT	C03672
4-HydroxyphenyllactateC13-1	C03672
5-MethylthioadenosineC12 PARENT	C00170
5-MethylthioadenosineC13-1	C00170
5-MethylthioadenosineC13-2	C00170
5-MethylthioadenosineC13-3	C00170
5-MethylthioadenosineC13-4	C00170
5-MethylthioadenosineC13-5	C00170
5-MethylthioadenosineC13-6	C00170
5-MethylthioadenosineC13-7	C00170
5-MethylthioadenosineC13-8	C00170
5-OxoprolineC12 PARENT	C01879
5-OxoprolineC13-1	C01879
5-OxoprolineC13-2	C01879
5-OxoprolineC13-3	C01879
5-OxoprolineC13-4	C01879
5-OxoprolineC13-5	C01879
6-PhosphogluconateC12 PARENT	C00345
6-PhosphogluconateC13-5	C00345
6-PhosphogluconateC13-6	C00345
a-KetoglutarateC12 PARENT	C00026
a-KetoglutarateC13-1	C00026
a-KetoglutarateC13-2	C00026
a-KetoglutarateC13-3	C00026
a-KetoglutarateC13-4	C00026
a-KetoglutarateC13-5	C00026
Acetyl-CoAC12 PARENT	C00024
Acetyl-CoAC13-1	C00024
Acetyl-CoAC13-10	C00024
Acetyl-CoAC13-2	C00024
Acetyl-CoAC13-3	C00024
Acetyl-CoAC13-4	C00024
Acetyl-CoAC13-5	C00024
Acetyl-CoAC13-6	C00024
Acetyl-CoAC13-7	C00024
Acetyl-CoAC13-8	C00024
Acetyl-CoAC13-9	C00024
AcetylcarnitineC12 PARENT	C02571
AcetylcarnitineC13-1	C02571
AcetylcarnitineC13-2	C02571
AcetylcarnitineC13-3	C02571
AconitateC12 PARENT	C00417
AconitateC13-1	C00417
AconitateC13-2	C00417
AconitateC13-3	C00417
AconitateC13-4	C00417
AconitateC13-5	C00417
AdenineC12 PARENT	C00147
AdenosineC12 PARENT	C00212
AdenosineC13-5	C00212
AdenosineC13-6	C00212
AdenosineC13-7	C00212
AdenosineC13-8	C00212
ADPC12 PARENT	C00008
ADPC13-1	C00008
ADPC13-2	C00008
ADPC13-4	C00008
ADPC13-5	C00008
ADPC13-6	C00008
ADPC13-7	C00008
ADPC13-8	C00008
AlanineC12 PARENT	C00041
AlanineC13-1	C00041
AlanineC13-2	C00041
AlanineC13-3	C00041
AlanineStd	C00041
AMPC12 PARENT	C00020
AMPC13-1	C00020
AMPC13-2	C00020
AMPC13-3	C00020
AMPC13-4	C00020
AMPC13-5	C00020
AMPC13-6	C00020
AMPC13-7	C00020
AMPC13-8	C00020
AMPC13-9	C00020
ArginineC12 PARENT	C00062
ArginineStd	C00062
ArgininosuccinateC12 PARENT	C03406
ArgininosuccinateC13-1	C03406
ArgininosuccinateC13-2	C03406
ArgininosuccinateC13-3	C03406
ArgininosuccinateC13-4	C03406
AsparagineC12 PARENT	C00152
AsparagineC13-1	C00152
AsparagineC13-2	C00152
AsparagineC13-3	C00152
AsparagineC13-4	C00152
AspartateC12 PARENT	C00049
AspartateC13-1	C00049
AspartateC13-2	C00049
AspartateC13-3	C00049
AspartateC13-4	C00049
AspartateStd	C00049
ATPC12 PARENT	C00002
ATPC13-1	C00002
ATPC13-2	C00002
ATPC13-3	C00002
ATPC13-4	C00002
ATPC13-5	C00002
ATPC13-6	C00002
ATPC13-7	C00002
ATPC13-8	C00002
ATPC13-9	C00002
CarnitineC12 PARENT	C00318
CDPC12 PARENT	C00112
CDPC13-1	C00112
CDPC13-2	C00112
CDPC13-3	C00112
CDPC13-5	C00112
CDPC13-6	C00112
CDPC13-7	C00112
CDP-cholineC12 PARENT	C00307
CDP-ethanolamineC12 PARENT	C00570
CholineC12 PARENT	C00114
CitrateC12 PARENT	C00158
CitrateC13-1	C00158
CitrateC13-2	C00158
CitrateC13-3	C00158
CitrateC13-4	C00158
CitrateC13-5	C00158
CitrateC13-6	C00158
CitrullineC12 PARENT	C00327
CMPC12 PARENT	C00055
CMPC13-5	C00055
CoAC12 PARENT	C00010
CoAC13-4	C00010
CoAC13-5	C00010
CoAC13-6	C00010
CoAC13-7	C00010
CoAC13-8	C00010
CoAC13-9	C00010
CreatineC12 PARENT	C00300
CreatinineC12 PARENT	C00791
CTPC12 PARENT	C00063
CTPC13-1	C00063
CTPC13-2	C00063
CTPC13-3	C00063
CTPC13-4	C00063
CTPC13-5	C00063
CTPC13-6	C00063
CTPC13-7	C00063
CTPC13-8	C00063
CystathionineC12 PARENT	C02291
CystathionineC13-1	C02291
CystathionineC13-2	C02291
CystathionineC13-3	C02291
CystathionineC13-4	C02291
CystineC12 PARENT	C00491
CystineStd	C00491
CytidineC12 PARENT	D07769
CytosineC12 PARENT	C00380
CytosineC13-1	C00380
CytosineC13-2	C00380
CytosineC13-3	C00380
DeoxyadenosineC12 PARENT	C00559
DeoxycytidineC12 PARENT	C00881
DeoxycytidineC13-5	C00881
DeoxythymidineC12 PARENT	C00214
DeoxyuridineC12 PARENT	C00526
dGMPC12 PARENT	C00362
dGTPC12 PARENT	C00286
DihydroorotateC12 PARENT	C00337
DihydroorotateC13-1	C00337
DihydroorotateC13-2	C00337
DihydroorotateC13-3	C00337
DihydroorotateC13-4	C00337
DimethylglycineC12 PARENT	C01026
dTMPC12 PARENT	C00364
FolateC12 PARENT	C00504
FructoseC12 PARENT	C00095
FructoseC13-1	C00095
FructoseC13-6	C00095
Fructose-1,6-bisphosphateC12 PARENT	C00354
Fructose-1,6-bisphosphateC13-3	C00354
Fructose-1,6-bisphosphateC13-5	C00354
Fructose-1,6-bisphosphateC13-6	C00354
GABAC12 PARENT	C00334
GDPC12 PARENT	C00035
GDPC13-1	C00035
GDPC13-4	C00035
GDPC13-5	C00035
GDPC13-6	C00035
GDPC13-7	C00035
GDPC13-8	C00035
Gluconic acidC12 PARENT	C00257
Gluconic acidC13-1	C00257
Gluconic acidC13-3	C00257
Gluconic acidC13-5	C00257
Gluconic acidC13-6	C00257
GlucosamineC12 PARENT	C00329
GlucoseC12 PARENT	C00031
GlucoseC13-5	C00031
GlucoseC13-6	C00031
Glucuronic acidC12 PARENT	C00191
Glucuronic acidC13-5	C00191
Glucuronic acidC13-6	C00191
GlutamateC12 PARENT	C00025
GlutamateC13-1	C00025
GlutamateC13-2	C00025
GlutamateC13-3	C00025
GlutamateC13-4	C00025
GlutamateC13-5	C00025
GlutamateStd	C00025
GlutamineC12 PARENT	C00064
GlutamineC13-1	C00064
GlutamineC13-2	C00064
GlutamineC13-3	C00064
GlutamineC13-4	C00064
GlutamineC13-5	C00064
GlutathioneC12 PARENT	C00051
GlutathioneC13-1	C00051
GlutathioneC13-2	C00051
GlutathioneC13-3	C00051
GlutathioneC13-4	C00051
GlutathioneC13-5	C00051
GlutathioneC13-6	C00051
Glutathione disulfideC12 PARENT	C00127
Glutathione disulfideC13-1	C00127
Glutathione disulfideC13-10	C00127
Glutathione disulfideC13-11	C00127
Glutathione disulfideC13-2	C00127
Glutathione disulfideC13-3	C00127
Glutathione disulfideC13-4	C00127
Glutathione disulfideC13-5	C00127
Glutathione disulfideC13-6	C00127
Glutathione disulfideC13-7	C00127
Glutathione disulfideC13-8	C00127
Glutathione disulfideC13-9	C00127
GlycerolC12 PARENT	C00116
GlycineC12 PARENT	C00037
GlycineC13-1	C00037
GlycineC13-2	C00037
GlycineStd	C00037
GMPC12 PARENT	C00144
GMPC13-1	C00144
GMPC13-4	C00144
GMPC13-5	C00144
GMPC13-6	C00144
GMPC13-7	C00144
GMPC13-8	C00144
GMPC13-9	C00144
GTPC12 PARENT	C00044
GTPC13-5	C00044
GuanosineC12 PARENT	C00387
Hexose phosphateC12 PARENT	C00085
Hexose phosphateC13-5	C00085
Hexose phosphateC13-6	C00085
HistidineC12 PARENT	C00135
HistidineStd	C00135
HMG-CoAC12 PARENT	C00356
HMG-CoAC13-1	C00356
HMG-CoAC13-10	C00356
HMG-CoAC13-11	C00356
HMG-CoAC13-2	C00356
HMG-CoAC13-5	C00356
HMG-CoAC13-6	C00356
HMG-CoAC13-7	C00356
HMG-CoAC13-8	C00356
HMG-CoAC13-9	C00356
HomocysteineC12 PARENT	C00155
HydroxyprolineC12 PARENT	C01157
HypoxanthineC12 PARENT	C00262
Inosine monophosphateC12 PARENT	C00130
InositolC12 PARENT	C00137
Isobutyryl-CoAC12 PARENT	C00630
Isobutyryl-CoAC13-1	C00630
Isobutyryl-CoAC13-2	C00630
Isobutyryl-CoAC13-5	C00630
Isobutyryl-CoAC13-6	C00630
Isobutyryl-CoAC13-7	C00630
Isobutyryl-CoAC13-8	C00630
IsoleucineC12 PARENT	C00407
LactateC12 PARENT	C00186
LactateC13-1	C00186
LactateC13-2	C00186
LactateC13-3	C00186
LeucineC12 PARENT	C00123
LeucineStd	C00123
LysineC12 PARENT	C00047
LysineC13-1	C00047
LysineStd	C00047
MalateC12 PARENT	C00149
MalateC13-1	C00149
MalateC13-2	C00149
MalateC13-3	C00149
MalateC13-4	C00149
Malonyl-CoAC12 PARENT	C00083
MethionineC12 PARENT	C00073
MethionineC13-1	C00073
MethionineC13-4	C00073
MethionineStd	C00073
N-AcetylglucosamineC12 PARENT	C00140
N-Acetylglucosamine-6-phosphateC12 PARENT	C00357
N-Acetylglucosamine-6-phosphateC13-6	C00357
N-Acetylglucosamine-6-phosphateC13-8	C00357
NAD+C12 PARENT	C00003
NAD+C13-1	C00003
NAD+C13-10	C00003
NAD+C13-11	C00003
NAD+C13-12	C00003
NAD+C13-13	C00003
NAD+C13-14	C00003
NAD+C13-2	C00003
NAD+C13-3	C00003
NAD+C13-4	C00003
NAD+C13-5	C00003
NAD+C13-6	C00003
NAD+C13-7	C00003
NAD+C13-8	C00003
NAD+C13-9	C00003
NADHC12 PARENT	C00004
NADHC13-1	C00004
NADHC13-10	C00004
NADHC13-11	C00004
NADHC13-12	C00004
NADHC13-13	C00004
NADHC13-2	C00004
NADHC13-3	C00004
NADHC13-4	C00004
NADHC13-5	C00004
NADHC13-6	C00004
NADHC13-7	C00004
NADHC13-8	C00004
NADHC13-9	C00004
NADP+C12 PARENT	C00006
NADP+C13-1	C00006
NADP+C13-10	C00006
NADP+C13-11	C00006
NADP+C13-12	C00006
NADP+C13-13	C00006
NADP+C13-14	C00006
NADP+C13-2	C00006
NADP+C13-3	C00006
NADP+C13-4	C00006
NADP+C13-5	C00006
NADP+C13-6	C00006
NADP+C13-7	C00006
NADP+C13-8	C00006
NADP+C13-9	C00006
NADPHC12 PARENT	C00005
NADPHC13-1	C00005
NADPHC13-10	C00005
NADPHC13-11	C00005
NADPHC13-12	C00005
NADPHC13-13	C00005
NADPHC13-2	C00005
NADPHC13-4	C00005
NADPHC13-5	C00005
NADPHC13-6	C00005
NADPHC13-7	C00005
NADPHC13-8	C00005
NADPHC13-9	C00005
NorvalineStd	NA
OrnithineC12 PARENT	C00077
OrotidineC12 PARENT	X00006
OrotidineC13-1	X00006
OrotidineC13-2	X00006
OrotidineC13-3	X00006
OrotidineC13-4	X00006
OrotidineC13-5	X00006
OrotidineC13-6	X00006
OrotidineC13-7	X00006
OrotidineC13-8	X00006
PalmitateC12 PARENT	C00249
PantothenateC12 PARENT	C00864
PhenylalanineC12 PARENT	C00079
PhenylalanineStd	C00079
PhosphateC12 PARENT	C00009
PhosphocholineC12 PARENT	C00588
PhosphocreatineC12 PARENT	C02305
PhosphoenolpyruvateC12 PARENT	C00074
PhosphoenolpyruvateC13-3	C00074
PhosphoethanolamineC12 PARENT	C00346
Phosphoribosyl pyrophosphateC12 PARENT	C00119
PhosphoserineC12 PARENT	C01005
PhosphoserineC13-3	C01005
ProlineC12 PARENT	C00148
ProlineC13-1	C00148
ProlineC13-2	C00148
ProlineC13-3	C00148
ProlineC13-4	C00148
ProlineC13-5	C00148
ProlineStd	C00148
Propanoyl-CoAC12 PARENT	C00100
Ribose-5-phosphateC12 PARENT	C00117
Ribose-5-phosphateC13-5	C00117
S-Adenosyl-L-methionineC12 PARENT	C00019
S-Adenosyl-L-methionineC13-1	C00019
S-Adenosyl-L-methionineC13-10	C00019
S-Adenosyl-L-methionineC13-2	C00019
S-Adenosyl-L-methionineC13-3	C00019
S-Adenosyl-L-methionineC13-4	C00019
S-Adenosyl-L-methionineC13-5	C00019
S-Adenosyl-L-methionineC13-6	C00019
S-Adenosyl-L-methionineC13-7	C00019
S-Adenosyl-L-methionineC13-8	C00019
S-Adenosyl-L-methionineC13-9	C00019
SarcosineC12 PARENT	C00213
SarcosineC13-2	C00213
Sedoheptulose-7-phosphateC12 PARENT	C05382
Sedoheptulose-7-phosphateC13-7	C05382
SerineC12 PARENT	C00065
SerineC13-1	C00065
SerineC13-2	C00065
SerineC13-3	C00065
SerineStd	C00065
SorbitolC12 PARENT	C00794
SorbitolC13-1	C00794
SorbitolC13-6	C00794
SuccinateC12 PARENT	C00042
SuccinateC13-2	C00042
SuccinateC13-3	C00042
SuccinateC13-4	C00042
Succinyl-CoAC12 PARENT	C00091
Succinyl-CoAC13-1	C00091
Succinyl-CoAC13-2	C00091
Succinyl-CoAC13-3	C00091
Succinyl-CoAC13-4	C00091
Succinyl-CoAC13-5	C00091
Succinyl-CoAC13-6	C00091
Succinyl-CoAC13-7	C00091
Succinyl-CoAC13-8	C00091
Succinyl-CoAC13-9	C00091
ThiosulfateC12 PARENT	C00320
ThreonineC12 PARENT	C00188
ThreonineStd	C00188
TryptophanC12 PARENT	C00078
TyrosineC12 PARENT	C00082
TyrosineStd	C00082
UDPC12 PARENT	C00015
UDPC13-1	C00015
UDPC13-2	C00015
UDPC13-3	C00015
UDPC13-4	C00015
UDPC13-5	C00015
UDPC13-6	C00015
UDPC13-7	C00015
UDPC13-8	C00015
UDP-glucoseC12 PARENT	C00029
UDP-glucoseC13-1	C00029
UDP-glucoseC13-10	C00029
UDP-glucoseC13-11	C00029
UDP-glucoseC13-12	C00029
UDP-glucoseC13-13	C00029
UDP-glucoseC13-14	C00029
UDP-glucoseC13-2	C00029
UDP-glucoseC13-3	C00029
UDP-glucoseC13-4	C00029
UDP-glucoseC13-5	C00029
UDP-glucoseC13-6	C00029
UDP-glucoseC13-7	C00029
UDP-glucoseC13-8	C00029
UDP-glucoseC13-9	C00029
UDP-N-acetylglucosamineC12 PARENT	C00043
UDP-N-acetylglucosamineC13-1	C00043
UDP-N-acetylglucosamineC13-10	C00043
UDP-N-acetylglucosamineC13-11	C00043
UDP-N-acetylglucosamineC13-12	C00043
UDP-N-acetylglucosamineC13-13	C00043
UDP-N-acetylglucosamineC13-14	C00043
UDP-N-acetylglucosamineC13-15	C00043
UDP-N-acetylglucosamineC13-16	C00043
UDP-N-acetylglucosamineC13-17	C00043
UDP-N-acetylglucosamineC13-2	C00043
UDP-N-acetylglucosamineC13-3	C00043
UDP-N-acetylglucosamineC13-4	C00043
UDP-N-acetylglucosamineC13-5	C00043
UDP-N-acetylglucosamineC13-6	C00043
UDP-N-acetylglucosamineC13-7	C00043
UDP-N-acetylglucosamineC13-8	C00043
UDP-N-acetylglucosamineC13-9	C00043
UMPC12 PARENT	C00105
UMPC13-1	C00105
UMPC13-2	C00105
UMPC13-3	C00105
UMPC13-5	C00105
UMPC13-6	C00105
UMPC13-7	C00105
UracilC12 PARENT	C00106
Uric acidC12 PARENT	C00366
UridineC12 PARENT	C00299
UTPC12 PARENT	C00075
UTPC13-1	C00075
UTPC13-2	C00075
UTPC13-3	C00075
UTPC13-4	C00075
UTPC13-5	C00075
UTPC13-6	C00075
UTPC13-7	C00075
UTPC13-8	C00075
ValineC12 PARENT	C00183
ValineStd	C00183
XanthineC12 PARENT	C00385
METABOLITES_END
#END