#METABOLOMICS WORKBENCH hjyoo2_20231007_033452 DATATRACK_ID:4380 STUDY_ID:ST002924 ANALYSIS_ID:AN004794 PROJECT_ID:PR001816
VERSION             	1
CREATED_ON             	October 11, 2023, 8:59 pm
#PROJECT
PR:PROJECT_TITLE                 	Gut sphingolipid metabolites in infants with atopic dermatitis associated with
PR:PROJECT_TITLE                 	food allergy
PR:PROJECT_SUMMARY               	This study determines S1P, ceradmides, sphingomyelins and diacylglycerols from
PR:PROJECT_SUMMARY               	infant feces to explore differential sphingolipid metabolism associated with
PR:PROJECT_SUMMARY               	food allergy in atopic dermatitis.
PR:INSTITUTE                     	Asan Medical Center
PR:LAST_NAME                     	Yoo
PR:FIRST_NAME                    	Hyun Ju
PR:ADDRESS                       	88, Olympic-ro, 43-gil, Songpa-gu, Seoul, Seoul, 05505, Korea, South
PR:EMAIL                         	yoohyunju@amc.seoul.kr
PR:PHONE                         	02-3010-4029
#STUDY
ST:STUDY_TITLE                   	Gut sphingolipid metabolites in infants with atopic dermatitis associated with
ST:STUDY_TITLE                   	food allergy - Part 2
ST:STUDY_SUMMARY                 	This study determines sphingolipids and diacylglycerols from infant feces to
ST:STUDY_SUMMARY                 	explore the lipid changes with food allergy in atopic dermatitis. Food allergy
ST:STUDY_SUMMARY                 	(FA) may be present in the range of 20–80% in atopic dermatitis (AD). Food
ST:STUDY_SUMMARY                 	sensitization through the skin can cause FA due to damage to the skin barrier,
ST:STUDY_SUMMARY                 	and failure to acquire tolerance to food allergens in the gut can equally cause
ST:STUDY_SUMMARY                 	the development of FA. Gut metabolites can influence the physical gut barrier
ST:STUDY_SUMMARY                 	and intestinal homeostasis. Therefore, it is possible that gut metabolites
ST:STUDY_SUMMARY                 	related to gut immunity play an important role in the development of FA.
ST:STUDY_SUMMARY                 	Sphingolipids are key factors in cell inflammatory response and affect gut
ST:STUDY_SUMMARY                 	epithelial cells and skin barrier integrity and function. FA is associated with
ST:STUDY_SUMMARY                 	a marked decrease in serum sphingolipid levels. However, there are no reports of
ST:STUDY_SUMMARY                 	FA-associated gut sphingolipid metabolites in infants by targeted metabolomics.
ST:STUDY_SUMMARY                 	In our previous study, we showed that when FA is present in various phenotypes
ST:STUDY_SUMMARY                 	of AD in early life, it might be associated with the later development of
ST:STUDY_SUMMARY                 	asthma. The discovery of a biomarker that can distinguish the phenotypes that
ST:STUDY_SUMMARY                 	accompany AD and FA from other AD phenotypes is therefore expedient.
ST:STUDY_SUMMARY                 	Consequently, we aimed to investigate whether FA in AD infants. can be
ST:STUDY_SUMMARY                 	classified as gut sphingolipid metabolites using targeted metabolomics.
ST:INSTITUTE                     	Asan Medical Center
ST:LAST_NAME                     	Yoo
ST:FIRST_NAME                    	Hyun Ju
ST:ADDRESS                       	88, Olympic-ro, 43-gil, Songpa-gu, Seoul, Seoul, 05505, Korea, South
ST:EMAIL                         	yoohyunju@amc.seoul.kr
ST:PHONE                         	02-3010-4029
#SUBJECT
SU:SUBJECT_TYPE                  	Human
SU:SUBJECT_SPECIES               	Homo sapiens
SU:TAXONOMY_ID                   	9606
SU:GENDER                        	Not applicable
SU:HUMAN_RACE                    	Pacific asian
#SUBJECT_SAMPLE_FACTORS:         	SUBJECT(optional)[tab]SAMPLE[tab]FACTORS(NAME:VALUE pairs separated by |)[tab]Raw file names and additional sample data
SUBJECT_SAMPLE_FACTORS           	1_AD_human feces_child_1_2_dilu	s_AD_1	Factor:AD	Subject=Cer_SM_SA_SO; Batch=set1; RAW_FILE_NAME=Cer_SM_SA_SO_set1.rdb
SUBJECT_SAMPLE_FACTORS           	4_AD_human feces_child_1_2_dilu	s_AD_2	Factor:AD	Subject=Cer_SM_SA_SO; Batch=set1; RAW_FILE_NAME=Cer_SM_SA_SO_set1.rdb
SUBJECT_SAMPLE_FACTORS           	10_AD_human feces_child_1_2_dilu	s_AD_3	Factor:AD	Subject=Cer_SM_SA_SO; Batch=set1; RAW_FILE_NAME=Cer_SM_SA_SO_set1.rdb
SUBJECT_SAMPLE_FACTORS           	13_AD_child_1_2_dilu	s_AD_4	Factor:AD	Subject=Cer_SM_SA_SO; Batch=set2; RAW_FILE_NAME=Cer_SM_SA_SO_set2.rdb
SUBJECT_SAMPLE_FACTORS           	24_AD_child_1_2_dilu	s_AD_5	Factor:AD	Subject=Cer_SM_SA_SO; Batch=set2; RAW_FILE_NAME=Cer_SM_SA_SO_set2.rdb
SUBJECT_SAMPLE_FACTORS           	25_AD_child_1_2_dilu	s_AD_6	Factor:AD	Subject=Cer_SM_SA_SO; Batch=set2; RAW_FILE_NAME=Cer_SM_SA_SO_set2.rdb
SUBJECT_SAMPLE_FACTORS           	33_AD_child_1_2_dilu	s_AD_7	Factor:AD	Subject=Cer_SM_SA_SO; Batch=set2; RAW_FILE_NAME=Cer_SM_SA_SO_set2.rdb
SUBJECT_SAMPLE_FACTORS           	39_AD_child_1_2_dilu	s_AD_8	Factor:AD	Subject=Cer_SM_SA_SO; Batch=set3; RAW_FILE_NAME=Cer_SM_SA_SO_set3.rdb
SUBJECT_SAMPLE_FACTORS           	41_AD_child_1_2_dilu	s_AD_9	Factor:AD	Subject=Cer_SM_SA_SO; Batch=set3; RAW_FILE_NAME=Cer_SM_SA_SO_set3.rdb
SUBJECT_SAMPLE_FACTORS           	46_AD_child_1_2_dilu	s_AD_10	Factor:AD	Subject=Cer_SM_SA_SO; Batch=set3; RAW_FILE_NAME=Cer_SM_SA_SO_set3.rdb
SUBJECT_SAMPLE_FACTORS           	51_AD_child_1_2_dilu	s_AD_12	Factor:AD	Subject=Cer_SM_SA_SO; Batch=set4; RAW_FILE_NAME=Cer_SM_SA_SO_set4.rdb
SUBJECT_SAMPLE_FACTORS           	53_AD_child_1_2_dilu	s_AD_13	Factor:AD	Subject=Cer_SM_SA_SO; Batch=set4; RAW_FILE_NAME=Cer_SM_SA_SO_set4.rdb
SUBJECT_SAMPLE_FACTORS           	55_AD_child_1_2_dilu	s_AD_14	Factor:AD	Subject=Cer_SM_SA_SO; Batch=set4; RAW_FILE_NAME=Cer_SM_SA_SO_set4.rdb
SUBJECT_SAMPLE_FACTORS           	56_AD_child_1_2_dilu	s_AD_15	Factor:AD	Subject=Cer_SM_SA_SO; Batch=set4; RAW_FILE_NAME=Cer_SM_SA_SO_set4.rdb
SUBJECT_SAMPLE_FACTORS           	57_AD_child_1_2_dilu	s_AD_16	Factor:AD	Subject=Cer_SM_SA_SO; Batch=set4; RAW_FILE_NAME=Cer_SM_SA_SO_set4.rdb
SUBJECT_SAMPLE_FACTORS           	62_AD_child_1_2_dilu	s_AD_11	Factor:AD	Subject=Cer_SM_SA_SO; Batch=set5; RAW_FILE_NAME=Cer_SM_SA_SO_set5.rdb
SUBJECT_SAMPLE_FACTORS           	64_AD_child_1_2_dilu	s_AD_17	Factor:AD	Subject=Cer_SM_SA_SO; Batch=set5; RAW_FILE_NAME=Cer_SM_SA_SO_set5.rdb
SUBJECT_SAMPLE_FACTORS           	66_AD_child_1_2_dilu	s_AD_18	Factor:AD	Subject=Cer_SM_SA_SO; Batch=set5; RAW_FILE_NAME=Cer_SM_SA_SO_set5.rdb
SUBJECT_SAMPLE_FACTORS           	68_AD_child_1_2_dilu	s_AD_19	Factor:AD	Subject=Cer_SM_SA_SO; Batch=set5; RAW_FILE_NAME=Cer_SM_SA_SO_set5.rdb
SUBJECT_SAMPLE_FACTORS           	11_mild AD_1/3 dilu	s_AD_20	Factor:AD	Subject=Cer_SM_SA_SO; Batch=set6; RAW_FILE_NAME=Cer_SM_SA_SO_set6.rdb
SUBJECT_SAMPLE_FACTORS           	12_moderate AD_1/3 dilu	s_AD_21	Factor:AD	Subject=Cer_SM_SA_SO; Batch=set6; RAW_FILE_NAME=Cer_SM_SA_SO_set6.rdb
SUBJECT_SAMPLE_FACTORS           	17_severe AD_1/3 dilu	s_AD_22	Factor:AD	Subject=Cer_SM_SA_SO; Batch=set6; RAW_FILE_NAME=Cer_SM_SA_SO_set6.rdb
SUBJECT_SAMPLE_FACTORS           	25_mild AD_1/3 dilu	s_AD_23	Factor:AD	Subject=Cer_SM_SA_SO; Batch=set7; RAW_FILE_NAME=Cer_SM_SA_SO_set7.rdb
SUBJECT_SAMPLE_FACTORS           	33_mild_AD_1/3 dilu	s_AD_24	Factor:AD	Subject=Cer_SM_SA_SO; Batch=set7; RAW_FILE_NAME=Cer_SM_SA_SO_set7.rdb
SUBJECT_SAMPLE_FACTORS           	34_mild AD_1/3 dilu	s_AD_25	Factor:AD	Subject=Cer_SM_SA_SO; Batch=set7; RAW_FILE_NAME=Cer_SM_SA_SO_set7.rdb
SUBJECT_SAMPLE_FACTORS           	36_mild AD_1/3 dilu	s_AD_26	Factor:AD	Subject=Cer_SM_SA_SO; Batch=set7; RAW_FILE_NAME=Cer_SM_SA_SO_set7.rdb
SUBJECT_SAMPLE_FACTORS           	47_moderate AD_1/3 dilu	s_AD_27	Factor:AD	Subject=Cer_SM_SA_SO; Batch=set8; RAW_FILE_NAME=Cer_SM_SA_SO_set8.rdb
SUBJECT_SAMPLE_FACTORS           	53_mild_AD_1/3 dilu	s_AD_28	Factor:AD	Subject=Cer_SM_SA_SO; Batch=set8; RAW_FILE_NAME=Cer_SM_SA_SO_set8.rdb
SUBJECT_SAMPLE_FACTORS           	66_mild AD_1/3 dilu	s_AD_29	Factor:AD	Subject=Cer_SM_SA_SO; Batch=set9; RAW_FILE_NAME=Cer_SM_SA_SO_set9.rdb
SUBJECT_SAMPLE_FACTORS           	78_moderate AD_1/3 dilu	s_AD_30	Factor:AD	Subject=Cer_SM_SA_SO; Batch=set9; RAW_FILE_NAME=Cer_SM_SA_SO_set9.rdb
SUBJECT_SAMPLE_FACTORS           	3_AD_human feces_child_1_2_dilu	s_AD_FA_1	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set1; RAW_FILE_NAME=Cer_SM_SA_SO_set1.rdb
SUBJECT_SAMPLE_FACTORS           	7_AD_human feces_child_1_2_dilu	s_AD_FA_2	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set1; RAW_FILE_NAME=Cer_SM_SA_SO_set1.rdb
SUBJECT_SAMPLE_FACTORS           	1_Disease_1/30	s_AD_FA_45	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set10; RAW_FILE_NAME=Cer_SM_SA_SO_set10.rdb
SUBJECT_SAMPLE_FACTORS           	2_Disease_1/30	s_AD_FA_46	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set10; RAW_FILE_NAME=Cer_SM_SA_SO_set10.rdb
SUBJECT_SAMPLE_FACTORS           	3_Disease_1/30	s_AD_FA_47	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set10; RAW_FILE_NAME=Cer_SM_SA_SO_set10.rdb
SUBJECT_SAMPLE_FACTORS           	4_Disease_1/30	s_AD_FA_48	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set10; RAW_FILE_NAME=Cer_SM_SA_SO_set10.rdb
SUBJECT_SAMPLE_FACTORS           	5_Disease_1/30	s_AD_FA_49	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set10; RAW_FILE_NAME=Cer_SM_SA_SO_set10.rdb
SUBJECT_SAMPLE_FACTORS           	6_Disease_1/30	s_AD_FA_50	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set10; RAW_FILE_NAME=Cer_SM_SA_SO_set10.rdb
SUBJECT_SAMPLE_FACTORS           	7_Disease_1/30	s_AD_FA_51	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set10; RAW_FILE_NAME=Cer_SM_SA_SO_set10.rdb
SUBJECT_SAMPLE_FACTORS           	8_Disease_1/30	s_AD_FA_52	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set10; RAW_FILE_NAME=Cer_SM_SA_SO_set10.rdb
SUBJECT_SAMPLE_FACTORS           	9_Disease_1/30	s_AD_FA_53	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set10; RAW_FILE_NAME=Cer_SM_SA_SO_set10.rdb
SUBJECT_SAMPLE_FACTORS           	10_Disease_1/30	s_AD_FA_54	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set10; RAW_FILE_NAME=Cer_SM_SA_SO_set10.rdb
SUBJECT_SAMPLE_FACTORS           	11_Disease_1/30	s_AD_FA_55	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set10; RAW_FILE_NAME=Cer_SM_SA_SO_set10.rdb
SUBJECT_SAMPLE_FACTORS           	12_Disease_1/30	s_AD_FA_56	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set10; RAW_FILE_NAME=Cer_SM_SA_SO_set10.rdb
SUBJECT_SAMPLE_FACTORS           	13_Disease_1/30	s_AD_FA_57	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set10; RAW_FILE_NAME=Cer_SM_SA_SO_set10.rdb
SUBJECT_SAMPLE_FACTORS           	14_Disease_1/30	s_AD_FA_58	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set10; RAW_FILE_NAME=Cer_SM_SA_SO_set10.rdb
SUBJECT_SAMPLE_FACTORS           	15_Disease_1/30	s_AD_FA_59	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set11; RAW_FILE_NAME=Cer_SM_SA_SO_set11.rdb
SUBJECT_SAMPLE_FACTORS           	16_Disease_1/30	s_AD_FA_60	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set11; RAW_FILE_NAME=Cer_SM_SA_SO_set11.rdb
SUBJECT_SAMPLE_FACTORS           	17_Disease_1/30	s_AD_FA_61	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set11; RAW_FILE_NAME=Cer_SM_SA_SO_set11.rdb
SUBJECT_SAMPLE_FACTORS           	18_Disease_1/30	s_AD_FA_62	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set11; RAW_FILE_NAME=Cer_SM_SA_SO_set11.rdb
SUBJECT_SAMPLE_FACTORS           	19_Disease_1/30	s_AD_FA_63	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set11; RAW_FILE_NAME=Cer_SM_SA_SO_set11.rdb
SUBJECT_SAMPLE_FACTORS           	20_Disease_1/30	s_AD_FA_64	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set11; RAW_FILE_NAME=Cer_SM_SA_SO_set11.rdb
SUBJECT_SAMPLE_FACTORS           	21_Disease_1/30	s_AD_FA_65	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set11; RAW_FILE_NAME=Cer_SM_SA_SO_set11.rdb
SUBJECT_SAMPLE_FACTORS           	22_Disease_1/30	s_AD_FA_66	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set11; RAW_FILE_NAME=Cer_SM_SA_SO_set11.rdb
SUBJECT_SAMPLE_FACTORS           	23_Disease_1/30	s_AD_FA_67	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set11; RAW_FILE_NAME=Cer_SM_SA_SO_set11.rdb
SUBJECT_SAMPLE_FACTORS           	24_Disease_1/30	s_AD_FA_68	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set11; RAW_FILE_NAME=Cer_SM_SA_SO_set11.rdb
SUBJECT_SAMPLE_FACTORS           	25_Disease_1/30	s_AD_FA_69	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set11; RAW_FILE_NAME=Cer_SM_SA_SO_set11.rdb
SUBJECT_SAMPLE_FACTORS           	26_Disease_1/30	s_AD_FA_70	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set11; RAW_FILE_NAME=Cer_SM_SA_SO_set11.rdb
SUBJECT_SAMPLE_FACTORS           	27_Disease_1/30	s_AD_FA_71	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set11; RAW_FILE_NAME=Cer_SM_SA_SO_set11.rdb
SUBJECT_SAMPLE_FACTORS           	28_Disease_1/30	s_AD_FA_72	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set11; RAW_FILE_NAME=Cer_SM_SA_SO_set11.rdb
SUBJECT_SAMPLE_FACTORS           	30_Disease_1/30	s_AD_FA_73	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set12; RAW_FILE_NAME=Cer_SM_SA_SO_set12.rdb
SUBJECT_SAMPLE_FACTORS           	31_Disease_1/30	s_AD_FA_74	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set12; RAW_FILE_NAME=Cer_SM_SA_SO_set12.rdb
SUBJECT_SAMPLE_FACTORS           	32_Disease_1/30	s_AD_FA_75	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set12; RAW_FILE_NAME=Cer_SM_SA_SO_set12.rdb
SUBJECT_SAMPLE_FACTORS           	33_Disease_1/30	s_AD_FA_76	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set12; RAW_FILE_NAME=Cer_SM_SA_SO_set12.rdb
SUBJECT_SAMPLE_FACTORS           	34_Disease_1/30	s_AD_FA_77	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set12; RAW_FILE_NAME=Cer_SM_SA_SO_set12.rdb
SUBJECT_SAMPLE_FACTORS           	35_Disease_1/30	s_AD_FA_78	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set12; RAW_FILE_NAME=Cer_SM_SA_SO_set12.rdb
SUBJECT_SAMPLE_FACTORS           	36_Disease_1/30	s_AD_FA_79	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set12; RAW_FILE_NAME=Cer_SM_SA_SO_set12.rdb
SUBJECT_SAMPLE_FACTORS           	37_Disease_1/30	s_AD_FA_80	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set12; RAW_FILE_NAME=Cer_SM_SA_SO_set12.rdb
SUBJECT_SAMPLE_FACTORS           	38_Disease_1/30	s_AD_FA_81	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set12; RAW_FILE_NAME=Cer_SM_SA_SO_set12.rdb
SUBJECT_SAMPLE_FACTORS           	39_Disease_1/30	s_AD_FA_82	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set12; RAW_FILE_NAME=Cer_SM_SA_SO_set12.rdb
SUBJECT_SAMPLE_FACTORS           	61_Disease_1/30	s_AD_FA_83	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set12; RAW_FILE_NAME=Cer_SM_SA_SO_set12.rdb
SUBJECT_SAMPLE_FACTORS           	16_AD_child_1_2_dilu	s_AD_FA_3	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set2; RAW_FILE_NAME=Cer_SM_SA_SO_set2.rdb
SUBJECT_SAMPLE_FACTORS           	35_AD_child_1_2_dilu	s_AD_FA_4	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set2; RAW_FILE_NAME=Cer_SM_SA_SO_set2.rdb
SUBJECT_SAMPLE_FACTORS           	38_AD_child_1_2_dilu	s_AD_FA_5	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set3; RAW_FILE_NAME=Cer_SM_SA_SO_set3.rdb
SUBJECT_SAMPLE_FACTORS           	42_AD_child_1_2_dilu	s_AD_FA_6	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set3; RAW_FILE_NAME=Cer_SM_SA_SO_set3.rdb
SUBJECT_SAMPLE_FACTORS           	45_AD_child_1_2_dilu	s_AD_FA_7	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set3; RAW_FILE_NAME=Cer_SM_SA_SO_set3.rdb
SUBJECT_SAMPLE_FACTORS           	54_AD_child_1_2_dilu	s_AD_FA_8	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set4; RAW_FILE_NAME=Cer_SM_SA_SO_set4.rdb
SUBJECT_SAMPLE_FACTORS           	63_AD_child_1_2_dilu	s_AD_FA_9	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set5; RAW_FILE_NAME=Cer_SM_SA_SO_set5.rdb
SUBJECT_SAMPLE_FACTORS           	67_AD_child_1_2_dilu	s_AD_FA_10	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set5; RAW_FILE_NAME=Cer_SM_SA_SO_set5.rdb
SUBJECT_SAMPLE_FACTORS           	5_moderate AD_1/3 dilu	s_AD_FA_11	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set6; RAW_FILE_NAME=Cer_SM_SA_SO_set6.rdb
SUBJECT_SAMPLE_FACTORS           	6_moderate AD_1/3 dilu	s_AD_FA_12	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set6; RAW_FILE_NAME=Cer_SM_SA_SO_set6.rdb
SUBJECT_SAMPLE_FACTORS           	13_moderate AD_1/3 dilu	s_AD_FA_13	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set6; RAW_FILE_NAME=Cer_SM_SA_SO_set6.rdb
SUBJECT_SAMPLE_FACTORS           	14_mild AD_1/3 dilu	s_AD_FA_14	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set6; RAW_FILE_NAME=Cer_SM_SA_SO_set6.rdb
SUBJECT_SAMPLE_FACTORS           	19_severe AD_1/3 dilu	s_AD_FA_15	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set6; RAW_FILE_NAME=Cer_SM_SA_SO_set6.rdb
SUBJECT_SAMPLE_FACTORS           	28_mild AD_1/3 dilu	s_AD_FA_16	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set7; RAW_FILE_NAME=Cer_SM_SA_SO_set7.rdb
SUBJECT_SAMPLE_FACTORS           	30_mild AD_1/3 dilu	s_AD_FA_17	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set7; RAW_FILE_NAME=Cer_SM_SA_SO_set7.rdb
SUBJECT_SAMPLE_FACTORS           	31_moderate AD_1/3 dilu	s_AD_FA_18	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set7; RAW_FILE_NAME=Cer_SM_SA_SO_set7.rdb
SUBJECT_SAMPLE_FACTORS           	35_moderate AD_1/3 dilu	s_AD_FA_19	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set7; RAW_FILE_NAME=Cer_SM_SA_SO_set7.rdb
SUBJECT_SAMPLE_FACTORS           	37_moderate AD_1/3 dilu	s_AD_FA_20	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set7; RAW_FILE_NAME=Cer_SM_SA_SO_set7.rdb
SUBJECT_SAMPLE_FACTORS           	38_mild AD_1/3 dilu	s_AD_FA_21	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set7; RAW_FILE_NAME=Cer_SM_SA_SO_set7.rdb
SUBJECT_SAMPLE_FACTORS           	39_moderate AD_1/3 dilu	s_AD_FA_22	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set7; RAW_FILE_NAME=Cer_SM_SA_SO_set7.rdb
SUBJECT_SAMPLE_FACTORS           	40_mild AD_1/3 dilu	s_AD_FA_23	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set7; RAW_FILE_NAME=Cer_SM_SA_SO_set7.rdb
SUBJECT_SAMPLE_FACTORS           	46_mild AD_1/3 dilu	s_AD_FA_24	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set8; RAW_FILE_NAME=Cer_SM_SA_SO_set8.rdb
SUBJECT_SAMPLE_FACTORS           	48_severe AD_1/3 dilu	s_AD_FA_25	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set8; RAW_FILE_NAME=Cer_SM_SA_SO_set8.rdb
SUBJECT_SAMPLE_FACTORS           	49_moderate AD_1/3 dilu	s_AD_FA_26	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set8; RAW_FILE_NAME=Cer_SM_SA_SO_set8.rdb
SUBJECT_SAMPLE_FACTORS           	51_severe AD_1/3 dilu	s_AD_FA_27	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set8; RAW_FILE_NAME=Cer_SM_SA_SO_set8.rdb
SUBJECT_SAMPLE_FACTORS           	54_severe AD_1/3 dilu	s_AD_FA_28	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set8; RAW_FILE_NAME=Cer_SM_SA_SO_set8.rdb
SUBJECT_SAMPLE_FACTORS           	55_mild AD_1/3 dilu	s_AD_FA_29	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set8; RAW_FILE_NAME=Cer_SM_SA_SO_set8.rdb
SUBJECT_SAMPLE_FACTORS           	56_moderate AD_1/3 dilu	s_AD_FA_30	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set8; RAW_FILE_NAME=Cer_SM_SA_SO_set8.rdb
SUBJECT_SAMPLE_FACTORS           	57_severe AD_1/3 dilu	s_AD_FA_31	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set8; RAW_FILE_NAME=Cer_SM_SA_SO_set8.rdb
SUBJECT_SAMPLE_FACTORS           	58_severe AD_1/3 dilu	s_AD_FA_32	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set8; RAW_FILE_NAME=Cer_SM_SA_SO_set8.rdb
SUBJECT_SAMPLE_FACTORS           	60_moderate AD_1/3 dilu	s_AD_FA_33	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set8; RAW_FILE_NAME=Cer_SM_SA_SO_set8.rdb
SUBJECT_SAMPLE_FACTORS           	65_moderate AD_1/3 dilu	s_AD_FA_34	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set9; RAW_FILE_NAME=Cer_SM_SA_SO_set9.rdb
SUBJECT_SAMPLE_FACTORS           	68_moderate AD_1/3 dilu	s_AD_FA_35	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set9; RAW_FILE_NAME=Cer_SM_SA_SO_set9.rdb
SUBJECT_SAMPLE_FACTORS           	69_severe AD_1/3 dilu	s_AD_FA_36	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set9; RAW_FILE_NAME=Cer_SM_SA_SO_set9.rdb
SUBJECT_SAMPLE_FACTORS           	70_moderate AD_1/3 dilu	s_AD_FA_37	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set9; RAW_FILE_NAME=Cer_SM_SA_SO_set9.rdb
SUBJECT_SAMPLE_FACTORS           	71_mild AD_1/3 dilu	s_AD_FA_38	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set9; RAW_FILE_NAME=Cer_SM_SA_SO_set9.rdb
SUBJECT_SAMPLE_FACTORS           	73_mild_AD_1/3 dilu	s_AD_FA_39	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set9; RAW_FILE_NAME=Cer_SM_SA_SO_set9.rdb
SUBJECT_SAMPLE_FACTORS           	75_moderate AD_1/3 dilu	s_AD_FA_40	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set9; RAW_FILE_NAME=Cer_SM_SA_SO_set9.rdb
SUBJECT_SAMPLE_FACTORS           	76_moderate AD_1/3 dilu	s_AD_FA_41	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set9; RAW_FILE_NAME=Cer_SM_SA_SO_set9.rdb
SUBJECT_SAMPLE_FACTORS           	77_mild AD_1/3 dilu	s_AD_FA_42	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set9; RAW_FILE_NAME=Cer_SM_SA_SO_set9.rdb
SUBJECT_SAMPLE_FACTORS           	79_severe AD_1/3 dilu	s_AD_FA_43	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set9; RAW_FILE_NAME=Cer_SM_SA_SO_set9.rdb
SUBJECT_SAMPLE_FACTORS           	80_mild AD_1/3 dilu	s_AD_FA_44	Factor:AD_FA	Subject=Cer_SM_SA_SO; Batch=set9; RAW_FILE_NAME=Cer_SM_SA_SO_set9.rdb
SUBJECT_SAMPLE_FACTORS           	5_control_human feces_child_1_2_dilu	s_Con_1	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set1; RAW_FILE_NAME=Cer_SM_SA_SO_set1.rdb
SUBJECT_SAMPLE_FACTORS           	9_control_human feces_child_1_2_dilu	s_Con_2	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set1; RAW_FILE_NAME=Cer_SM_SA_SO_set1.rdb
SUBJECT_SAMPLE_FACTORS           	11_control_human feces_child_1_2_dilu	s_Con_3	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set1; RAW_FILE_NAME=Cer_SM_SA_SO_set1.rdb
SUBJECT_SAMPLE_FACTORS           	14_control_human feces_child_1_2_dilu	s_Con_4	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set1; RAW_FILE_NAME=Cer_SM_SA_SO_set1.rdb
SUBJECT_SAMPLE_FACTORS           	15_control_human feces_child_1_2_dilu	s_Con_5	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set1; RAW_FILE_NAME=Cer_SM_SA_SO_set1.rdb
SUBJECT_SAMPLE_FACTORS           	41_Control_1/30	s_Con_27	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set10; RAW_FILE_NAME=Cer_SM_SA_SO_set10.rdb
SUBJECT_SAMPLE_FACTORS           	43_Control_1/30	s_Con_28	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set10; RAW_FILE_NAME=Cer_SM_SA_SO_set10.rdb
SUBJECT_SAMPLE_FACTORS           	44_Control_1/30	s_Con_29	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set10; RAW_FILE_NAME=Cer_SM_SA_SO_set10.rdb
SUBJECT_SAMPLE_FACTORS           	45_Control_1/30	s_Con_30	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set10; RAW_FILE_NAME=Cer_SM_SA_SO_set10.rdb
SUBJECT_SAMPLE_FACTORS           	48_Control_1/30	s_Con_31	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set10; RAW_FILE_NAME=Cer_SM_SA_SO_set10.rdb
SUBJECT_SAMPLE_FACTORS           	49_Control_1/30	s_Con_32	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set10; RAW_FILE_NAME=Cer_SM_SA_SO_set10.rdb
SUBJECT_SAMPLE_FACTORS           	50_Control_1/30	s_Con_33	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set11; RAW_FILE_NAME=Cer_SM_SA_SO_set11.rdb
SUBJECT_SAMPLE_FACTORS           	51_Control_1/30	s_Con_34	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set11; RAW_FILE_NAME=Cer_SM_SA_SO_set11.rdb
SUBJECT_SAMPLE_FACTORS           	52_Control_1/30	s_Con_35	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set11; RAW_FILE_NAME=Cer_SM_SA_SO_set11.rdb
SUBJECT_SAMPLE_FACTORS           	53_Control_1/30	s_Con_36	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set11; RAW_FILE_NAME=Cer_SM_SA_SO_set11.rdb
SUBJECT_SAMPLE_FACTORS           	54_Control_1/30	s_Con_37	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set11; RAW_FILE_NAME=Cer_SM_SA_SO_set11.rdb
SUBJECT_SAMPLE_FACTORS           	55_Control_1/30	s_Con_38	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set11; RAW_FILE_NAME=Cer_SM_SA_SO_set11.rdb
SUBJECT_SAMPLE_FACTORS           	56_Control_1/30	s_Con_39	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set12; RAW_FILE_NAME=Cer_SM_SA_SO_set12.rdb
SUBJECT_SAMPLE_FACTORS           	57_Control_1/30	s_Con_40	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set12; RAW_FILE_NAME=Cer_SM_SA_SO_set12.rdb
SUBJECT_SAMPLE_FACTORS           	58_Control_1/30	s_Con_41	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set12; RAW_FILE_NAME=Cer_SM_SA_SO_set12.rdb
SUBJECT_SAMPLE_FACTORS           	59_Control_1/30	s_Con_42	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set12; RAW_FILE_NAME=Cer_SM_SA_SO_set12.rdb
SUBJECT_SAMPLE_FACTORS           	60_Control_1/30	s_Con_43	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set12; RAW_FILE_NAME=Cer_SM_SA_SO_set12.rdb
SUBJECT_SAMPLE_FACTORS           	62_Control_1/30	s_Con_44	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set12; RAW_FILE_NAME=Cer_SM_SA_SO_set12.rdb
SUBJECT_SAMPLE_FACTORS           	63_Control_1/30	s_Con_45	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set12; RAW_FILE_NAME=Cer_SM_SA_SO_set12.rdb
SUBJECT_SAMPLE_FACTORS           	64_Control_1/30	s_Con_46	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set12; RAW_FILE_NAME=Cer_SM_SA_SO_set12.rdb
SUBJECT_SAMPLE_FACTORS           	18_control_child_1_2_dilu	s_Con_6	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set2; RAW_FILE_NAME=Cer_SM_SA_SO_set2.rdb
SUBJECT_SAMPLE_FACTORS           	22_control_child_1_2_dilu	s_Con_7	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set2; RAW_FILE_NAME=Cer_SM_SA_SO_set2.rdb
SUBJECT_SAMPLE_FACTORS           	23_control_child_1_2_dilu	s_Con_8	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set3; RAW_FILE_NAME=Cer_SM_SA_SO_set3.rdb
SUBJECT_SAMPLE_FACTORS           	26_control_child_1_2_dilu	s_Con_9	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set3; RAW_FILE_NAME=Cer_SM_SA_SO_set3.rdb
SUBJECT_SAMPLE_FACTORS           	29_control_child_1_2_dilu	s_Con_10	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set3; RAW_FILE_NAME=Cer_SM_SA_SO_set3.rdb
SUBJECT_SAMPLE_FACTORS           	30_control_child_1_2_dilu	s_Con_11	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set3; RAW_FILE_NAME=Cer_SM_SA_SO_set3.rdb
SUBJECT_SAMPLE_FACTORS           	31_control_child_1_2_dilu	s_Con_12	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set4; RAW_FILE_NAME=Cer_SM_SA_SO_set4.rdb
SUBJECT_SAMPLE_FACTORS           	34_control_child_1_2_dilu	s_Con_13	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set4; RAW_FILE_NAME=Cer_SM_SA_SO_set4.rdb
SUBJECT_SAMPLE_FACTORS           	43_control_child_1_2_dilu	s_Con_14	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set4; RAW_FILE_NAME=Cer_SM_SA_SO_set4.rdb
SUBJECT_SAMPLE_FACTORS           	58_control_child_1_2_dilu	s_Con_15	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set5; RAW_FILE_NAME=Cer_SM_SA_SO_set5.rdb
SUBJECT_SAMPLE_FACTORS           	59_control_child_1_2_dilu	s_Con_16	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set5; RAW_FILE_NAME=Cer_SM_SA_SO_set5.rdb
SUBJECT_SAMPLE_FACTORS           	60_control_child_1_2_dilu	s_Con_17	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set5; RAW_FILE_NAME=Cer_SM_SA_SO_set5.rdb
SUBJECT_SAMPLE_FACTORS           	1_control_1/3 dilu	s_Con_19	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set6; RAW_FILE_NAME=Cer_SM_SA_SO_set6.rdb
SUBJECT_SAMPLE_FACTORS           	3_control_1/3 dilu	s_Con_20	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set6; RAW_FILE_NAME=Cer_SM_SA_SO_set6.rdb
SUBJECT_SAMPLE_FACTORS           	4_control_1/3 dilu	s_Con_21	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set6; RAW_FILE_NAME=Cer_SM_SA_SO_set6.rdb
SUBJECT_SAMPLE_FACTORS           	32_mild AD_1/3 dilu	s_Con_18	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set7; RAW_FILE_NAME=Cer_SM_SA_SO_set7.rdb
SUBJECT_SAMPLE_FACTORS           	42_control_1/3 dilu	s_Con_22	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set8; RAW_FILE_NAME=Cer_SM_SA_SO_set8.rdb
SUBJECT_SAMPLE_FACTORS           	43_control_1/3 dilu	s_Con_23	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set8; RAW_FILE_NAME=Cer_SM_SA_SO_set8.rdb
SUBJECT_SAMPLE_FACTORS           	44_control_1/3 dilu	s_Con_24	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set8; RAW_FILE_NAME=Cer_SM_SA_SO_set8.rdb
SUBJECT_SAMPLE_FACTORS           	61_control_1/3 dilu	s_Con_25	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set9; RAW_FILE_NAME=Cer_SM_SA_SO_set9.rdb
SUBJECT_SAMPLE_FACTORS           	64_control_1/3 dilu	s_Con_26	Factor:Con	Subject=Cer_SM_SA_SO; Batch=set9; RAW_FILE_NAME=Cer_SM_SA_SO_set9.rdb
SUBJECT_SAMPLE_FACTORS           	1_AD_child	d_AD_1	Factor:AD	Subject=DAG; Batch=set1; RAW_FILE_NAME=DAG_set1.rdb
SUBJECT_SAMPLE_FACTORS           	4_AD_child	d_AD_2	Factor:AD	Subject=DAG; Batch=set1; RAW_FILE_NAME=DAG_set1.rdb
SUBJECT_SAMPLE_FACTORS           	10_AD_child	d_AD_3	Factor:AD	Subject=DAG; Batch=set1; RAW_FILE_NAME=DAG_set1.rdb
SUBJECT_SAMPLE_FACTORS           	13_AD_child	d_AD_4	Factor:AD	Subject=DAG; Batch=set2; RAW_FILE_NAME=DAG_set2.rdb
SUBJECT_SAMPLE_FACTORS           	24_AD_child	d_AD_5	Factor:AD	Subject=DAG; Batch=set2; RAW_FILE_NAME=DAG_set2.rdb
SUBJECT_SAMPLE_FACTORS           	25_AD_child	d_AD_6	Factor:AD	Subject=DAG; Batch=set2; RAW_FILE_NAME=DAG_set2.rdb
SUBJECT_SAMPLE_FACTORS           	33_AD_child	d_AD_7	Factor:AD	Subject=DAG; Batch=set2; RAW_FILE_NAME=DAG_set2.rdb
SUBJECT_SAMPLE_FACTORS           	39_AD_child	d_AD_8	Factor:AD	Subject=DAG; Batch=set3; RAW_FILE_NAME=DAG_set3.rdb
SUBJECT_SAMPLE_FACTORS           	41_AD_child	d_AD_9	Factor:AD	Subject=DAG; Batch=set3; RAW_FILE_NAME=DAG_set3.rdb
SUBJECT_SAMPLE_FACTORS           	46_AD_child	d_AD_10	Factor:AD	Subject=DAG; Batch=set3; RAW_FILE_NAME=DAG_set3.rdb
SUBJECT_SAMPLE_FACTORS           	51_AD_child	d_AD_12	Factor:AD	Subject=DAG; Batch=set4; RAW_FILE_NAME=DAG_set4.rdb
SUBJECT_SAMPLE_FACTORS           	53_AD_child	d_AD_13	Factor:AD	Subject=DAG; Batch=set4; RAW_FILE_NAME=DAG_set4.rdb
SUBJECT_SAMPLE_FACTORS           	55_AD_child	d_AD_14	Factor:AD	Subject=DAG; Batch=set4; RAW_FILE_NAME=DAG_set4.rdb
SUBJECT_SAMPLE_FACTORS           	56_AD_child	d_AD_15	Factor:AD	Subject=DAG; Batch=set4; RAW_FILE_NAME=DAG_set4.rdb
SUBJECT_SAMPLE_FACTORS           	57_AD_child	d_AD_16	Factor:AD	Subject=DAG; Batch=set4; RAW_FILE_NAME=DAG_set4.rdb
SUBJECT_SAMPLE_FACTORS           	62_AD_child	d_AD_11	Factor:AD	Subject=DAG; Batch=set5; RAW_FILE_NAME=DAG_set5.rdb
SUBJECT_SAMPLE_FACTORS           	64_AD_child	d_AD_17	Factor:AD	Subject=DAG; Batch=set5; RAW_FILE_NAME=DAG_set5.rdb
SUBJECT_SAMPLE_FACTORS           	66_AD_child	d_AD_18	Factor:AD	Subject=DAG; Batch=set5; RAW_FILE_NAME=DAG_set5.rdb
SUBJECT_SAMPLE_FACTORS           	68_AD_child	d_AD_19	Factor:AD	Subject=DAG; Batch=set5; RAW_FILE_NAME=DAG_set5.rdb
SUBJECT_SAMPLE_FACTORS           	11_mild AD	d_AD_20	Factor:AD	Subject=DAG; Batch=set6; RAW_FILE_NAME=DAG_set6.rdb
SUBJECT_SAMPLE_FACTORS           	12_moderate AD	d_AD_21	Factor:AD	Subject=DAG; Batch=set6; RAW_FILE_NAME=DAG_set6.rdb
SUBJECT_SAMPLE_FACTORS           	17_severe AD	d_AD_22	Factor:AD	Subject=DAG; Batch=set6; RAW_FILE_NAME=DAG_set6.rdb
SUBJECT_SAMPLE_FACTORS           	25_mild AD	d_AD_23	Factor:AD	Subject=DAG; Batch=set7; RAW_FILE_NAME=DAG_set7.rdb
SUBJECT_SAMPLE_FACTORS           	33_mild AD	d_AD_24	Factor:AD	Subject=DAG; Batch=set7; RAW_FILE_NAME=DAG_set7.rdb
SUBJECT_SAMPLE_FACTORS           	34_mild AD	d_AD_25	Factor:AD	Subject=DAG; Batch=set7; RAW_FILE_NAME=DAG_set7.rdb
SUBJECT_SAMPLE_FACTORS           	36_mild AD	d_AD_26	Factor:AD	Subject=DAG; Batch=set7; RAW_FILE_NAME=DAG_set7.rdb
SUBJECT_SAMPLE_FACTORS           	47_moderate AD	d_AD_27	Factor:AD	Subject=DAG; Batch=set8; RAW_FILE_NAME=DAG_set8.rdb
SUBJECT_SAMPLE_FACTORS           	53_mild_AD	d_AD_28	Factor:AD	Subject=DAG; Batch=set8; RAW_FILE_NAME=DAG_set8.rdb
SUBJECT_SAMPLE_FACTORS           	66_mild AD	d_AD_29	Factor:AD	Subject=DAG; Batch=set9; RAW_FILE_NAME=DAG_set9.rdb
SUBJECT_SAMPLE_FACTORS           	78_moderate AD	d_AD_30	Factor:AD	Subject=DAG; Batch=set9; RAW_FILE_NAME=DAG_set9.rdb
SUBJECT_SAMPLE_FACTORS           	3_AD_child	d_AD_FA_1	Factor:AD_FA	Subject=DAG; Batch=set1; RAW_FILE_NAME=DAG_set1.rdb
SUBJECT_SAMPLE_FACTORS           	7_AD_child	d_AD_FA_2	Factor:AD_FA	Subject=DAG; Batch=set1; RAW_FILE_NAME=DAG_set1.rdb
SUBJECT_SAMPLE_FACTORS           	1_Disease	d_AD_FA_45	Factor:AD_FA	Subject=DAG; Batch=set10; RAW_FILE_NAME=DAG_set10.rdb
SUBJECT_SAMPLE_FACTORS           	2_Disease	d_AD_FA_46	Factor:AD_FA	Subject=DAG; Batch=set10; RAW_FILE_NAME=DAG_set10.rdb
SUBJECT_SAMPLE_FACTORS           	3_Disease	d_AD_FA_47	Factor:AD_FA	Subject=DAG; Batch=set10; RAW_FILE_NAME=DAG_set10.rdb
SUBJECT_SAMPLE_FACTORS           	4_Disease	d_AD_FA_48	Factor:AD_FA	Subject=DAG; Batch=set10; RAW_FILE_NAME=DAG_set10.rdb
SUBJECT_SAMPLE_FACTORS           	5_Disease	d_AD_FA_49	Factor:AD_FA	Subject=DAG; Batch=set10; RAW_FILE_NAME=DAG_set10.rdb
SUBJECT_SAMPLE_FACTORS           	6_Disease	d_AD_FA_50	Factor:AD_FA	Subject=DAG; Batch=set10; RAW_FILE_NAME=DAG_set10.rdb
SUBJECT_SAMPLE_FACTORS           	7_Disease	d_AD_FA_51	Factor:AD_FA	Subject=DAG; Batch=set10; RAW_FILE_NAME=DAG_set10.rdb
SUBJECT_SAMPLE_FACTORS           	8_Disease	d_AD_FA_52	Factor:AD_FA	Subject=DAG; Batch=set10; RAW_FILE_NAME=DAG_set10.rdb
SUBJECT_SAMPLE_FACTORS           	9_Disease	d_AD_FA_53	Factor:AD_FA	Subject=DAG; Batch=set10; RAW_FILE_NAME=DAG_set10.rdb
SUBJECT_SAMPLE_FACTORS           	10_Disease	d_AD_FA_54	Factor:AD_FA	Subject=DAG; Batch=set10; RAW_FILE_NAME=DAG_set10.rdb
SUBJECT_SAMPLE_FACTORS           	11_Disease	d_AD_FA_55	Factor:AD_FA	Subject=DAG; Batch=set10; RAW_FILE_NAME=DAG_set10.rdb
SUBJECT_SAMPLE_FACTORS           	12_Disease	d_AD_FA_56	Factor:AD_FA	Subject=DAG; Batch=set10; RAW_FILE_NAME=DAG_set10.rdb
SUBJECT_SAMPLE_FACTORS           	13_Disease	d_AD_FA_57	Factor:AD_FA	Subject=DAG; Batch=set10; RAW_FILE_NAME=DAG_set10.rdb
SUBJECT_SAMPLE_FACTORS           	14_Disease	d_AD_FA_58	Factor:AD_FA	Subject=DAG; Batch=set10; RAW_FILE_NAME=DAG_set10.rdb
SUBJECT_SAMPLE_FACTORS           	15_Disease	d_AD_FA_59	Factor:AD_FA	Subject=DAG; Batch=set11; RAW_FILE_NAME=DAG_set11.rdb
SUBJECT_SAMPLE_FACTORS           	16_Disease	d_AD_FA_60	Factor:AD_FA	Subject=DAG; Batch=set11; RAW_FILE_NAME=DAG_set11.rdb
SUBJECT_SAMPLE_FACTORS           	17_Disease	d_AD_FA_61	Factor:AD_FA	Subject=DAG; Batch=set11; RAW_FILE_NAME=DAG_set11.rdb
SUBJECT_SAMPLE_FACTORS           	18_Disease	d_AD_FA_62	Factor:AD_FA	Subject=DAG; Batch=set11; RAW_FILE_NAME=DAG_set11.rdb
SUBJECT_SAMPLE_FACTORS           	19_Disease	d_AD_FA_63	Factor:AD_FA	Subject=DAG; Batch=set11; RAW_FILE_NAME=DAG_set11.rdb
SUBJECT_SAMPLE_FACTORS           	20_Disease	d_AD_FA_64	Factor:AD_FA	Subject=DAG; Batch=set11; RAW_FILE_NAME=DAG_set11.rdb
SUBJECT_SAMPLE_FACTORS           	21_Disease	d_AD_FA_65	Factor:AD_FA	Subject=DAG; Batch=set11; RAW_FILE_NAME=DAG_set11.rdb
SUBJECT_SAMPLE_FACTORS           	22_Disease	d_AD_FA_66	Factor:AD_FA	Subject=DAG; Batch=set11; RAW_FILE_NAME=DAG_set11.rdb
SUBJECT_SAMPLE_FACTORS           	23_Disease	d_AD_FA_67	Factor:AD_FA	Subject=DAG; Batch=set11; RAW_FILE_NAME=DAG_set11.rdb
SUBJECT_SAMPLE_FACTORS           	24_Disease	d_AD_FA_68	Factor:AD_FA	Subject=DAG; Batch=set11; RAW_FILE_NAME=DAG_set11.rdb
SUBJECT_SAMPLE_FACTORS           	25_Disease	d_AD_FA_69	Factor:AD_FA	Subject=DAG; Batch=set11; RAW_FILE_NAME=DAG_set11.rdb
SUBJECT_SAMPLE_FACTORS           	26_Disease	d_AD_FA_70	Factor:AD_FA	Subject=DAG; Batch=set11; RAW_FILE_NAME=DAG_set11.rdb
SUBJECT_SAMPLE_FACTORS           	27_Disease	d_AD_FA_71	Factor:AD_FA	Subject=DAG; Batch=set11; RAW_FILE_NAME=DAG_set11.rdb
SUBJECT_SAMPLE_FACTORS           	28_Disease	d_AD_FA_72	Factor:AD_FA	Subject=DAG; Batch=set11; RAW_FILE_NAME=DAG_set11.rdb
SUBJECT_SAMPLE_FACTORS           	30_Disease	d_AD_FA_73	Factor:AD_FA	Subject=DAG; Batch=set12; RAW_FILE_NAME=DAG_set12.rdb
SUBJECT_SAMPLE_FACTORS           	31_Disease	d_AD_FA_74	Factor:AD_FA	Subject=DAG; Batch=set12; RAW_FILE_NAME=DAG_set12.rdb
SUBJECT_SAMPLE_FACTORS           	32_Disease	d_AD_FA_75	Factor:AD_FA	Subject=DAG; Batch=set12; RAW_FILE_NAME=DAG_set12.rdb
SUBJECT_SAMPLE_FACTORS           	33_Disease	d_AD_FA_76	Factor:AD_FA	Subject=DAG; Batch=set12; RAW_FILE_NAME=DAG_set12.rdb
SUBJECT_SAMPLE_FACTORS           	34_Disease	d_AD_FA_77	Factor:AD_FA	Subject=DAG; Batch=set12; RAW_FILE_NAME=DAG_set12.rdb
SUBJECT_SAMPLE_FACTORS           	35_Disease	d_AD_FA_78	Factor:AD_FA	Subject=DAG; Batch=set12; RAW_FILE_NAME=DAG_set12.rdb
SUBJECT_SAMPLE_FACTORS           	36_Disease	d_AD_FA_79	Factor:AD_FA	Subject=DAG; Batch=set12; RAW_FILE_NAME=DAG_set12.rdb
SUBJECT_SAMPLE_FACTORS           	37_Disease	d_AD_FA_80	Factor:AD_FA	Subject=DAG; Batch=set12; RAW_FILE_NAME=DAG_set12.rdb
SUBJECT_SAMPLE_FACTORS           	38_Disease	d_AD_FA_81	Factor:AD_FA	Subject=DAG; Batch=set12; RAW_FILE_NAME=DAG_set12.rdb
SUBJECT_SAMPLE_FACTORS           	39_Disease	d_AD_FA_82	Factor:AD_FA	Subject=DAG; Batch=set12; RAW_FILE_NAME=DAG_set12.rdb
SUBJECT_SAMPLE_FACTORS           	61_Disease	d_AD_FA_83	Factor:AD_FA	Subject=DAG; Batch=set12; RAW_FILE_NAME=DAG_set12.rdb
SUBJECT_SAMPLE_FACTORS           	16_AD_child	d_AD_FA_3	Factor:AD_FA	Subject=DAG; Batch=set2; RAW_FILE_NAME=DAG_set2.rdb
SUBJECT_SAMPLE_FACTORS           	35_AD_child	d_AD_FA_4	Factor:AD_FA	Subject=DAG; Batch=set2; RAW_FILE_NAME=DAG_set2.rdb
SUBJECT_SAMPLE_FACTORS           	38_AD_child	d_AD_FA_5	Factor:AD_FA	Subject=DAG; Batch=set3; RAW_FILE_NAME=DAG_set3.rdb
SUBJECT_SAMPLE_FACTORS           	42_AD_child	d_AD_FA_6	Factor:AD_FA	Subject=DAG; Batch=set3; RAW_FILE_NAME=DAG_set3.rdb
SUBJECT_SAMPLE_FACTORS           	45_AD_child	d_AD_FA_7	Factor:AD_FA	Subject=DAG; Batch=set3; RAW_FILE_NAME=DAG_set3.rdb
SUBJECT_SAMPLE_FACTORS           	54_AD_child	d_AD_FA_8	Factor:AD_FA	Subject=DAG; Batch=set4; RAW_FILE_NAME=DAG_set4.rdb
SUBJECT_SAMPLE_FACTORS           	63_AD_child	d_AD_FA_9	Factor:AD_FA	Subject=DAG; Batch=set5; RAW_FILE_NAME=DAG_set5.rdb
SUBJECT_SAMPLE_FACTORS           	67_AD_child	d_AD_FA_10	Factor:AD_FA	Subject=DAG; Batch=set5; RAW_FILE_NAME=DAG_set5.rdb
SUBJECT_SAMPLE_FACTORS           	5_moderate AD	d_AD_FA_11	Factor:AD_FA	Subject=DAG; Batch=set6; RAW_FILE_NAME=DAG_set6.rdb
SUBJECT_SAMPLE_FACTORS           	6_moderate AD	d_AD_FA_12	Factor:AD_FA	Subject=DAG; Batch=set6; RAW_FILE_NAME=DAG_set6.rdb
SUBJECT_SAMPLE_FACTORS           	13_moderate AD	d_AD_FA_13	Factor:AD_FA	Subject=DAG; Batch=set6; RAW_FILE_NAME=DAG_set6.rdb
SUBJECT_SAMPLE_FACTORS           	14_mild AD	d_AD_FA_14	Factor:AD_FA	Subject=DAG; Batch=set6; RAW_FILE_NAME=DAG_set6.rdb
SUBJECT_SAMPLE_FACTORS           	19_severe AD	d_AD_FA_15	Factor:AD_FA	Subject=DAG; Batch=set6; RAW_FILE_NAME=DAG_set6.rdb
SUBJECT_SAMPLE_FACTORS           	28_mild AD	d_AD_FA_16	Factor:AD_FA	Subject=DAG; Batch=set7; RAW_FILE_NAME=DAG_set7.rdb
SUBJECT_SAMPLE_FACTORS           	30_mild AD	d_AD_FA_17	Factor:AD_FA	Subject=DAG; Batch=set7; RAW_FILE_NAME=DAG_set7.rdb
SUBJECT_SAMPLE_FACTORS           	31_moderate AD	d_AD_FA_18	Factor:AD_FA	Subject=DAG; Batch=set7; RAW_FILE_NAME=DAG_set7.rdb
SUBJECT_SAMPLE_FACTORS           	35_moderate AD	d_AD_FA_19	Factor:AD_FA	Subject=DAG; Batch=set7; RAW_FILE_NAME=DAG_set7.rdb
SUBJECT_SAMPLE_FACTORS           	37_moderate AD	d_AD_FA_20	Factor:AD_FA	Subject=DAG; Batch=set7; RAW_FILE_NAME=DAG_set7.rdb
SUBJECT_SAMPLE_FACTORS           	38_mild AD	d_AD_FA_21	Factor:AD_FA	Subject=DAG; Batch=set7; RAW_FILE_NAME=DAG_set7.rdb
SUBJECT_SAMPLE_FACTORS           	39_moderate AD	d_AD_FA_22	Factor:AD_FA	Subject=DAG; Batch=set7; RAW_FILE_NAME=DAG_set7.rdb
SUBJECT_SAMPLE_FACTORS           	40_mild AD	d_AD_FA_23	Factor:AD_FA	Subject=DAG; Batch=set7; RAW_FILE_NAME=DAG_set7.rdb
SUBJECT_SAMPLE_FACTORS           	46_mild AD	d_AD_FA_24	Factor:AD_FA	Subject=DAG; Batch=set8; RAW_FILE_NAME=DAG_set8.rdb
SUBJECT_SAMPLE_FACTORS           	48_severe AD	d_AD_FA_25	Factor:AD_FA	Subject=DAG; Batch=set8; RAW_FILE_NAME=DAG_set8.rdb
SUBJECT_SAMPLE_FACTORS           	49_moderate AD	d_AD_FA_26	Factor:AD_FA	Subject=DAG; Batch=set8; RAW_FILE_NAME=DAG_set8.rdb
SUBJECT_SAMPLE_FACTORS           	51_severe AD	d_AD_FA_27	Factor:AD_FA	Subject=DAG; Batch=set8; RAW_FILE_NAME=DAG_set8.rdb
SUBJECT_SAMPLE_FACTORS           	54_severe AD	d_AD_FA_28	Factor:AD_FA	Subject=DAG; Batch=set8; RAW_FILE_NAME=DAG_set8.rdb
SUBJECT_SAMPLE_FACTORS           	55_mild AD	d_AD_FA_29	Factor:AD_FA	Subject=DAG; Batch=set8; RAW_FILE_NAME=DAG_set8.rdb
SUBJECT_SAMPLE_FACTORS           	56_moderate AD	d_AD_FA_30	Factor:AD_FA	Subject=DAG; Batch=set8; RAW_FILE_NAME=DAG_set8.rdb
SUBJECT_SAMPLE_FACTORS           	57_severe AD	d_AD_FA_31	Factor:AD_FA	Subject=DAG; Batch=set8; RAW_FILE_NAME=DAG_set8.rdb
SUBJECT_SAMPLE_FACTORS           	58_severe AD	d_AD_FA_32	Factor:AD_FA	Subject=DAG; Batch=set8; RAW_FILE_NAME=DAG_set8.rdb
SUBJECT_SAMPLE_FACTORS           	60_moderate AD	d_AD_FA_33	Factor:AD_FA	Subject=DAG; Batch=set8; RAW_FILE_NAME=DAG_set8.rdb
SUBJECT_SAMPLE_FACTORS           	65_moderate AD	d_AD_FA_34	Factor:AD_FA	Subject=DAG; Batch=set9; RAW_FILE_NAME=DAG_set9.rdb
SUBJECT_SAMPLE_FACTORS           	68_moderate AD	d_AD_FA_35	Factor:AD_FA	Subject=DAG; Batch=set9; RAW_FILE_NAME=DAG_set9.rdb
SUBJECT_SAMPLE_FACTORS           	69_severe AD	d_AD_FA_36	Factor:AD_FA	Subject=DAG; Batch=set9; RAW_FILE_NAME=DAG_set9.rdb
SUBJECT_SAMPLE_FACTORS           	70_moderate AD	d_AD_FA_37	Factor:AD_FA	Subject=DAG; Batch=set9; RAW_FILE_NAME=DAG_set9.rdb
SUBJECT_SAMPLE_FACTORS           	71_mild AD	d_AD_FA_38	Factor:AD_FA	Subject=DAG; Batch=set9; RAW_FILE_NAME=DAG_set9.rdb
SUBJECT_SAMPLE_FACTORS           	73_mild_AD	d_AD_FA_39	Factor:AD_FA	Subject=DAG; Batch=set9; RAW_FILE_NAME=DAG_set9.rdb
SUBJECT_SAMPLE_FACTORS           	75_moderate AD	d_AD_FA_40	Factor:AD_FA	Subject=DAG; Batch=set9; RAW_FILE_NAME=DAG_set9.rdb
SUBJECT_SAMPLE_FACTORS           	76_moderate AD	d_AD_FA_41	Factor:AD_FA	Subject=DAG; Batch=set9; RAW_FILE_NAME=DAG_set9.rdb
SUBJECT_SAMPLE_FACTORS           	77_mild AD	d_AD_FA_42	Factor:AD_FA	Subject=DAG; Batch=set9; RAW_FILE_NAME=DAG_set9.rdb
SUBJECT_SAMPLE_FACTORS           	79_severe AD	d_AD_FA_43	Factor:AD_FA	Subject=DAG; Batch=set9; RAW_FILE_NAME=DAG_set9.rdb
SUBJECT_SAMPLE_FACTORS           	80_mild AD	d_AD_FA_44	Factor:AD_FA	Subject=DAG; Batch=set9; RAW_FILE_NAME=DAG_set9.rdb
SUBJECT_SAMPLE_FACTORS           	5_control_child	d_Con_1	Factor:Con	Subject=DAG; Batch=set1; RAW_FILE_NAME=DAG_set1.rdb
SUBJECT_SAMPLE_FACTORS           	9_control_child	d_Con_2	Factor:Con	Subject=DAG; Batch=set1; RAW_FILE_NAME=DAG_set1.rdb
SUBJECT_SAMPLE_FACTORS           	11_control_child	d_Con_3	Factor:Con	Subject=DAG; Batch=set1; RAW_FILE_NAME=DAG_set1.rdb
SUBJECT_SAMPLE_FACTORS           	14_control_child	d_Con_4	Factor:Con	Subject=DAG; Batch=set1; RAW_FILE_NAME=DAG_set1.rdb
SUBJECT_SAMPLE_FACTORS           	15_control_child	d_Con_5	Factor:Con	Subject=DAG; Batch=set1; RAW_FILE_NAME=DAG_set1.rdb
SUBJECT_SAMPLE_FACTORS           	41_Control	d_Con_27	Factor:Con	Subject=DAG; Batch=set10; RAW_FILE_NAME=DAG_set10.rdb
SUBJECT_SAMPLE_FACTORS           	43_Control	d_Con_28	Factor:Con	Subject=DAG; Batch=set10; RAW_FILE_NAME=DAG_set10.rdb
SUBJECT_SAMPLE_FACTORS           	44_Control	d_Con_29	Factor:Con	Subject=DAG; Batch=set10; RAW_FILE_NAME=DAG_set10.rdb
SUBJECT_SAMPLE_FACTORS           	45_Control	d_Con_30	Factor:Con	Subject=DAG; Batch=set10; RAW_FILE_NAME=DAG_set10.rdb
SUBJECT_SAMPLE_FACTORS           	48_Control	d_Con_31	Factor:Con	Subject=DAG; Batch=set10; RAW_FILE_NAME=DAG_set10.rdb
SUBJECT_SAMPLE_FACTORS           	49_Control	d_Con_32	Factor:Con	Subject=DAG; Batch=set10; RAW_FILE_NAME=DAG_set10.rdb
SUBJECT_SAMPLE_FACTORS           	50_Control	d_Con_33	Factor:Con	Subject=DAG; Batch=set11; RAW_FILE_NAME=DAG_set11.rdb
SUBJECT_SAMPLE_FACTORS           	51_Control	d_Con_34	Factor:Con	Subject=DAG; Batch=set11; RAW_FILE_NAME=DAG_set11.rdb
SUBJECT_SAMPLE_FACTORS           	52_Control	d_Con_35	Factor:Con	Subject=DAG; Batch=set11; RAW_FILE_NAME=DAG_set11.rdb
SUBJECT_SAMPLE_FACTORS           	53_Control	d_Con_36	Factor:Con	Subject=DAG; Batch=set11; RAW_FILE_NAME=DAG_set11.rdb
SUBJECT_SAMPLE_FACTORS           	54_Control	d_Con_37	Factor:Con	Subject=DAG; Batch=set11; RAW_FILE_NAME=DAG_set11.rdb
SUBJECT_SAMPLE_FACTORS           	55_Control	d_Con_38	Factor:Con	Subject=DAG; Batch=set11; RAW_FILE_NAME=DAG_set11.rdb
SUBJECT_SAMPLE_FACTORS           	56_Control	d_Con_39	Factor:Con	Subject=DAG; Batch=set12; RAW_FILE_NAME=DAG_set12.rdb
SUBJECT_SAMPLE_FACTORS           	57_Control	d_Con_40	Factor:Con	Subject=DAG; Batch=set12; RAW_FILE_NAME=DAG_set12.rdb
SUBJECT_SAMPLE_FACTORS           	58_Control	d_Con_41	Factor:Con	Subject=DAG; Batch=set12; RAW_FILE_NAME=DAG_set12.rdb
SUBJECT_SAMPLE_FACTORS           	59_Control	d_Con_42	Factor:Con	Subject=DAG; Batch=set12; RAW_FILE_NAME=DAG_set12.rdb
SUBJECT_SAMPLE_FACTORS           	60_Control	d_Con_43	Factor:Con	Subject=DAG; Batch=set12; RAW_FILE_NAME=DAG_set12.rdb
SUBJECT_SAMPLE_FACTORS           	62_Control	d_Con_44	Factor:Con	Subject=DAG; Batch=set12; RAW_FILE_NAME=DAG_set12.rdb
SUBJECT_SAMPLE_FACTORS           	63_Control	d_Con_45	Factor:Con	Subject=DAG; Batch=set12; RAW_FILE_NAME=DAG_set12.rdb
SUBJECT_SAMPLE_FACTORS           	64_Control	d_Con_46	Factor:Con	Subject=DAG; Batch=set12; RAW_FILE_NAME=DAG_set12.rdb
SUBJECT_SAMPLE_FACTORS           	18_control_child	d_Con_6	Factor:Con	Subject=DAG; Batch=set2; RAW_FILE_NAME=DAG_set2.rdb
SUBJECT_SAMPLE_FACTORS           	22_control_child	d_Con_7	Factor:Con	Subject=DAG; Batch=set2; RAW_FILE_NAME=DAG_set2.rdb
SUBJECT_SAMPLE_FACTORS           	23_control_child	d_Con_8	Factor:Con	Subject=DAG; Batch=set3; RAW_FILE_NAME=DAG_set3.rdb
SUBJECT_SAMPLE_FACTORS           	26_control_child	d_Con_9	Factor:Con	Subject=DAG; Batch=set3; RAW_FILE_NAME=DAG_set3.rdb
SUBJECT_SAMPLE_FACTORS           	29_control_child	d_Con_10	Factor:Con	Subject=DAG; Batch=set3; RAW_FILE_NAME=DAG_set3.rdb
SUBJECT_SAMPLE_FACTORS           	30_control_child	d_Con_11	Factor:Con	Subject=DAG; Batch=set3; RAW_FILE_NAME=DAG_set3.rdb
SUBJECT_SAMPLE_FACTORS           	31_control_child	d_Con_12	Factor:Con	Subject=DAG; Batch=set4; RAW_FILE_NAME=DAG_set4.rdb
SUBJECT_SAMPLE_FACTORS           	34_control_child	d_Con_13	Factor:Con	Subject=DAG; Batch=set4; RAW_FILE_NAME=DAG_set4.rdb
SUBJECT_SAMPLE_FACTORS           	43_control_child	d_Con_14	Factor:Con	Subject=DAG; Batch=set4; RAW_FILE_NAME=DAG_set4.rdb
SUBJECT_SAMPLE_FACTORS           	58_control_child	d_Con_15	Factor:Con	Subject=DAG; Batch=set5; RAW_FILE_NAME=DAG_set5.rdb
SUBJECT_SAMPLE_FACTORS           	59_control_child	d_Con_16	Factor:Con	Subject=DAG; Batch=set5; RAW_FILE_NAME=DAG_set5.rdb
SUBJECT_SAMPLE_FACTORS           	60_control_child	d_Con_17	Factor:Con	Subject=DAG; Batch=set5; RAW_FILE_NAME=DAG_set5.rdb
SUBJECT_SAMPLE_FACTORS           	1_control	d_Con_19	Factor:Con	Subject=DAG; Batch=set6; RAW_FILE_NAME=DAG_set6.rdb
SUBJECT_SAMPLE_FACTORS           	3_control	d_Con_20	Factor:Con	Subject=DAG; Batch=set6; RAW_FILE_NAME=DAG_set6.rdb
SUBJECT_SAMPLE_FACTORS           	4_control	d_Con_21	Factor:Con	Subject=DAG; Batch=set6; RAW_FILE_NAME=DAG_set6.rdb
SUBJECT_SAMPLE_FACTORS           	32_mild AD	d_Con_18	Factor:Con	Subject=DAG; Batch=set7; RAW_FILE_NAME=DAG_set7.rdb
SUBJECT_SAMPLE_FACTORS           	42_control	d_Con_22	Factor:Con	Subject=DAG; Batch=set8; RAW_FILE_NAME=DAG_set8.rdb
SUBJECT_SAMPLE_FACTORS           	43_control	d_Con_23	Factor:Con	Subject=DAG; Batch=set8; RAW_FILE_NAME=DAG_set8.rdb
SUBJECT_SAMPLE_FACTORS           	44_control	d_Con_24	Factor:Con	Subject=DAG; Batch=set8; RAW_FILE_NAME=DAG_set8.rdb
SUBJECT_SAMPLE_FACTORS           	61_control	d_Con_25	Factor:Con	Subject=DAG; Batch=set9; RAW_FILE_NAME=DAG_set9.rdb
SUBJECT_SAMPLE_FACTORS           	64_control	d_Con_26	Factor:Con	Subject=DAG; Batch=set9; RAW_FILE_NAME=DAG_set9.rdb
#COLLECTION
CO:COLLECTION_SUMMARY            	The study population consisted of 158 six-month-old infants (46 healthy infants,
CO:COLLECTION_SUMMARY            	30 only AD group, and 82 with combined AD and FA) involved in the Cohort for
CO:COLLECTION_SUMMARY            	Childhood Origin of Asthma and Allergic Diseases (COCOA) (reference: BMC Pulm
CO:COLLECTION_SUMMARY            	Med 2014, 14:109.)
CO:SAMPLE_TYPE                   	Feces
#TREATMENT
TR:TREATMENT_SUMMARY             	no treatment
#SAMPLEPREP
SP:SAMPLEPREP_SUMMARY            	~40 mg of feces was used and lipids were extracted by Bligh and Dyer method
SP:SAMPLEPREP_SUMMARY            	after adding internal standard solutions (50 μl of 100 nM C18 ceramide-d7 and
SP:SAMPLEPREP_SUMMARY            	C18:1 Sphingomyelin-d9 and 200 μl of 1 μM 1,3-19:0-d5). Organic solutions
SP:SAMPLEPREP_SUMMARY            	containing the lipids were dried using a vacuum centrifuge and stored at
SP:SAMPLEPREP_SUMMARY            	–20°C until LC-MS/MS analysis. The dried matter was reconstituted with
SP:SAMPLEPREP_SUMMARY            	methanol and injected into the LC-MS/MS system.
#CHROMATOGRAPHY
CH:CHROMATOGRAPHY_SUMMARY        	Ceramides, sphingomyelines, sphinganine, sphingosine
CH:CHROMATOGRAPHY_TYPE           	Reversed phase
CH:INSTRUMENT_NAME               	Agilent 1290 Infinity
CH:COLUMN_NAME                   	Agilent Pursuit 5 C18 (150 x 2.0 mm, 5um)
CH:SOLVENT_A                     	5 mM ammonium formate/MeOH/tetrahydrofuran (500/200/300, v/v/v)
CH:SOLVENT_B                     	5 mM ammonium formate/MeOH/ tetrahydrofuran (100/200/700, v/v/v)
CH:FLOW_GRADIENT                 	50 % of B at 0 min, 50 % of B for 5 min, 50-70 % of B for 3 min, 70 % of B for 7
CH:FLOW_GRADIENT                 	min, 70-90 % of B for 7 min, 90 % of B for 3 min, 90-50 % of B for 0.1 min, 50 %
CH:FLOW_GRADIENT                 	of B for 4.9 min
CH:FLOW_RATE                     	200 uL/min
CH:COLUMN_TEMPERATURE            	35
#ANALYSIS
AN:ANALYSIS_TYPE                 	MS
AN:ACQUISITION_PARAMETERS_FILE   	MS_metadata.docx
#MS
MS:INSTRUMENT_NAME               	ABI Sciex 5500 QTrap
MS:INSTRUMENT_TYPE               	QTRAP
MS:MS_TYPE                       	ESI
MS:ION_MODE                      	POSITIVE
MS:MS_COMMENTS                   	Multiple reaction monitoring (MRM) was performed in the positive ion mode and
MS:MS_COMMENTS                   	the extracted ion chromatogram corresponding to the specific transition for each
MS:MS_COMMENTS                   	lipid was used for quantification. The calibration range for each lipid was
MS:MS_COMMENTS                   	0.1-1000 nM (r2 ≥ 0.99). Data analysis was performed by using Analyst 1.5.2
MS:MS_COMMENTS                   	software.
#MS_METABOLITE_DATA
MS_METABOLITE_DATA:UNITS	pmol/mg
MS_METABOLITE_DATA_START
Samples	s_AD_1	s_AD_2	s_AD_3	s_AD_4	s_AD_5	s_AD_6	s_AD_7	s_AD_8	s_AD_9	s_AD_10	s_AD_11	s_AD_12	s_AD_13	s_AD_14	s_AD_15	s_AD_16	s_AD_17	s_AD_18	s_AD_19	s_AD_20	s_AD_21	s_AD_22	s_AD_23	s_AD_24	s_AD_25	s_AD_26	s_AD_27	s_AD_28	s_AD_29	s_AD_30	s_AD_FA_1	s_AD_FA_2	s_AD_FA_3	s_AD_FA_4	s_AD_FA_5	s_AD_FA_6	s_AD_FA_7	s_AD_FA_8	s_AD_FA_9	s_AD_FA_10	s_AD_FA_11	s_AD_FA_12	s_AD_FA_13	s_AD_FA_14	s_AD_FA_15	s_AD_FA_16	s_AD_FA_17	s_AD_FA_18	s_AD_FA_19	s_AD_FA_20	s_AD_FA_21	s_AD_FA_22	s_AD_FA_23	s_AD_FA_24	s_AD_FA_25	s_AD_FA_26	s_AD_FA_27	s_AD_FA_28	s_AD_FA_29	s_AD_FA_30	s_AD_FA_31	s_AD_FA_32	s_AD_FA_33	s_AD_FA_34	s_AD_FA_35	s_AD_FA_36	s_AD_FA_37	s_AD_FA_38	s_AD_FA_39	s_AD_FA_40	s_AD_FA_41	s_AD_FA_42	s_AD_FA_43	s_AD_FA_44	s_AD_FA_45	s_AD_FA_46	s_AD_FA_47	s_AD_FA_48	s_AD_FA_49	s_AD_FA_50	s_AD_FA_51	s_AD_FA_52	s_AD_FA_53	s_AD_FA_54	s_AD_FA_55	s_AD_FA_56	s_AD_FA_57	s_AD_FA_58	s_AD_FA_59	s_AD_FA_60	s_AD_FA_61	s_AD_FA_62	s_AD_FA_63	s_AD_FA_64	s_AD_FA_65	s_AD_FA_66	s_AD_FA_67	s_AD_FA_68	s_AD_FA_69	s_AD_FA_70	s_AD_FA_71	s_AD_FA_72	s_AD_FA_73	s_AD_FA_74	s_AD_FA_75	s_AD_FA_76	s_AD_FA_77	s_AD_FA_78	s_AD_FA_79	s_AD_FA_80	s_AD_FA_81	s_AD_FA_82	s_AD_FA_83	s_Con_1	s_Con_2	s_Con_3	s_Con_4	s_Con_5	s_Con_6	s_Con_7	s_Con_8	s_Con_9	s_Con_10	s_Con_11	s_Con_12	s_Con_13	s_Con_14	s_Con_15	s_Con_16	s_Con_17	s_Con_18	s_Con_19	s_Con_20	s_Con_21	s_Con_22	s_Con_23	s_Con_24	s_Con_25	s_Con_26	s_Con_27	s_Con_28	s_Con_29	s_Con_30	s_Con_31	s_Con_32	s_Con_33	s_Con_34	s_Con_35	s_Con_36	s_Con_37	s_Con_38	s_Con_39	s_Con_40	s_Con_41	s_Con_42	s_Con_43	s_Con_44	s_Con_45	s_Con_46
Factors	Factor:AD	Factor:AD	Factor:AD	Factor:AD	Factor:AD	Factor:AD	Factor:AD	Factor:AD	Factor:AD	Factor:AD	Factor:AD	Factor:AD	Factor:AD	Factor:AD	Factor:AD	Factor:AD	Factor:AD	Factor:AD	Factor:AD	Factor:AD	Factor:AD	Factor:AD	Factor:AD	Factor:AD	Factor:AD	Factor:AD	Factor:AD	Factor:AD	Factor:AD	Factor:AD	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:AD_FA	Factor:Con	Factor:Con	Factor:Con	Factor:Con	Factor:Con	Factor:Con	Factor:Con	Factor:Con	Factor:Con	Factor:Con	Factor:Con	Factor:Con	Factor:Con	Factor:Con	Factor:Con	Factor:Con	Factor:Con	Factor:Con	Factor:Con	Factor:Con	Factor:Con	Factor:Con	Factor:Con	Factor:Con	Factor:Con	Factor:Con	Factor:Con	Factor:Con	Factor:Con	Factor:Con	Factor:Con	Factor:Con	Factor:Con	Factor:Con	Factor:Con	Factor:Con	Factor:Con	Factor:Con	Factor:Con	Factor:Con	Factor:Con	Factor:Con	Factor:Con	Factor:Con	Factor:Con	Factor:Con
C14_Ceramide	8.139130435	7.261538462	11.68	3.04157377	8.334857143	7.049309091	4.669935484	6.25434986	8.714883561	4.021650914	18.33494354	13.14487982	21.04502529	10.2230837	14.90942628	13.18291273	8.168467211	4.580503576	4.045883994	1.628408269	2.427177254	13.18547643	3.098642923	2.002532248	0.126185517	3.392252671	3.745125439	9.717170084	5.643994869	11.09886116	1.477894737	9.476923077	7.994434783	2.172708571	13.91855316	9.346614625	9.489922612	12.60235839	3.161963051	7.604624277	11.53952822	3.704939193	2.449043716	3.32506884	1.153952822	1.097752535	0.630656587	5.41411236	2.8710554	1.15825858	2.529180131	3.30294905	1.820693295	4.662376689	7.860394108	0.728647199	1.190870206	2.892849323	1.782977617	1.143758708	2.161161143	7.219527663	0.375942974	1.40602165	3.82238806	9.237437811	1.386781034	2.550249534	0.158919938	1.07250516	0.843771832	3.702938433	1.525968983	9.861538962	6.350518629	2.481420561	7.615084112	11.96260486	27.29562617	10.4051838	10.101	6.957131691	46.95279252	15.28738148	15.89926217	2.407802969	16.95921299	7.160556594	5.26106716	10.3746963	13.68566852	19.25185459	18.7441992	8.364598891	19.14972274	7.886621811	23.64187705	10.14169316	37.99304991	27.08536784	3.814160533	7.256246243	38.2578537	5.019455192	12.38480854	3.063704053	19.82883986	10.53156062	10.92229466	3.66655516	11.69168399	27.60700356	6.513527402	12.49811321	11.23404255	8.15483871	7.560784314	8.444444444	8.193391304	5.872941176	8.980119147	11.4738073	10.26778512	7.0378891	4.639369348	12.14381642	5.411453744	9.011594696	12.4752953	8.432335433	15.44865523	2.774853996	5.133864932	2.920048792	7.676882962	4.404267516	9.236727707	2.022499364	1.638959997	15.51252336	15.84109414	6.687558621	20.202	25.24575701	25.62858487	4.689244833	6.650115888	11.18900891	13.47239317	8.493781885	4.906065552	40.77145433	43.80311231	9.140985623	20.27000712	16.17380006	50.21273836	17.78288968	20.33073905
C16_Ceramide	18.29463556	29.7230341	15.69890977	9.266984852	17.27064497	18.79739164	11.75325983	26.52025378	31.29982105	20.45135558	41.63040674	29.82543641	49.27680798	13.9680798	23.55777224	20.71195324	14.64120832	9.410841855	6.658934169	14.29189301	18.94268281	32.4419591	16.31358025	11.26218327	4.922770866	10.93781544	20.84614013	28.69930186	16.79220084	23.76111601	11.29018789	42.09881698	28.38392955	15.60313442	44.03969416	33.91932145	39.5977343	30.98465956	10.47078269	23.17176681	32.65050822	26.45609155	19.45143653	18.20182635	20.11537539	8.160562343	6.991643007	22.88478192	18.53287189	9.045775885	14.6244654	16.28088771	21.26436879	24.13655571	26.53924012	10.98819209	21.45406777	18.5081212	10.47870613	14.13489425	16.19626369	29.20327631	7.80933384	14.29715713	18.30036113	23.99560626	12.32400749	20.95229399	2.453015894	16.53958453	6.460775206	15.57150197	15.12209045	23.02139481	62.26623794	47.27151125	58.37459807	85.92740836	80.53311897	102.7887103	64.12866559	63.23662087	139.5272026	95.42098802	50.70250804	46.85665217	83.33376206	40.86839586	105.8806667	68.28688372	86.944	88.92	96.70776471	78.92376471	123.272	92.34506667	117.7950968	116.5333333	166.1866667	160.3382857	47.54375758	54.38295652	89.68037614	47.4976149	58.53184855	31.55760769	113.5429844	63.25547142	91.53853007	45.05412027	92.13434298	118.6656214	66.65699332	22.9094681	30.72002843	17.18858733	18.36145565	15.6607129	19.39387268	14.14114338	29.26956239	31.79416789	40.78822936	41.5677959	25.28678304	28.81440467	24.87531172	13.08847837	21.12324829	12.91821882	24.85210257	21.44358179	17.47233853	14.59021606	26.50175532	20.69161094	30.7750228	11.0696573	11.21410275	88.7113583	67.03925967	73.15516133	84.22620579	107.6951768	117.072005	45.26836364	47.50991304	87.30327273	85.43294118	55.22118919	41.73697561	175.5955457	128.6468419	75.33151596	82.92705712	106.5335655	205.732081	105.906844	77.54574403
C18_Ceramide	4.250931677	15.62959707	6.810285714	1.98121766	8.997935103	19.49262537	1.996422114	6.475273011	8.319456989	2.826058422	20.21661806	8.709155975	14.19739819	4.400275545	5.921457042	24.03106201	3.755126024	4.997309417	1.37943405	5.526755395	2.320281325	7.12877095	6.491961195	7.796385454	0.716382766	2.258479223	4.486667308	13.78488601	6.512129934	11.41173246	3.868270677	28.37186813	26.65404643	4.483303835	25.0849714	47.27871322	46.70240628	8.052866978	5.171124593	21.22312447	4.68242128	6.814427982	9.915114836	2.412069367	12.40985272	1.870303106	0.373269795	9.64519949	3.163303351	1.846760829	7.772688234	7.97583804	8.634442799	14.21220663	10.20259434	2.406469663	5.812926536	10.18302869	2.081073113	2.752530464	4.06750623	17.0258337	3.472901926	6.977282072	8.467836257	8.864766082	1.782553755	14.69880757	0.398008438	3.075150476	0.950097984	2.137467105	16.00123355	16.54643513	10.09654775	7.837751351	20.53837838	24.43174054	22.42637838	25.71762162	10.17989189	28.31536118	54.3744	99.62331204	15.22753912	32.77736089	67.30196302	8.096288288	27.1254321	38.77907551	30.31019943	18.71813443	13.68868555	17.13185185	32.28695157	47.20776955	32.78999602	46.12421652	159.6044318	61.18518519	26.1304003	17.87671498	20.72154474	46.76963077	18.68001324	19.09080921	55.90879841	24.86585369	56.04003972	7.630861966	56.8173921	33.34841708	43.752572	5.597843666	25.02030395	6.112073733	6.663529412	3.970793651	8.729306143	9.994748106	8.446057421	8.698127925	22.4767653	24.3503147	22.68610166	6.79800995	14.26717694	9.053099446	6.796100604	6.412957633	1.924388966	14.03002793	2.280635171	6.801102204	35.00471698	4.909198113	19.97830189	3.518241627	2.814278611	44.02115413	17.56325379	33.10774278	16.74324324	22.04367568	22.95228596	12.01825365	7.436216855	34.2637037	29.72880174	8.581360027	10.1955411	157.7083085	33.51378113	60.87846938	23.8362597	87.1919545	60.15416951	38.58494538	20.38208078
C18_1_Ceramide	4.412041278	9.639524361	8.467763338	0.368008346	9.569064935	11.61924298	4.087917889	5.029969455	5.240526316	2.981678766	25.59219049	6.47904466	11.13590141	9.645972203	13.12475285	15.50393632	4.17344581	4.395760115	2.612787503	2.013513347	1.309683874	11.83840336	9.835310747	2.176006008	0.42160382	4.408005008	5.503286368	9.495106762	6.270293759	10.1004732	1.749231766	10.47774387	13.81386166	1.673293247	11.01758271	8.14475888	10.77597403	9.157971486	2.572559034	4.040744831	4.110556723	4.3217711	2.982852474	2.329315476	2.986098644	1.127716511	2.078442817	7.768470083	1.381982154	0.759851767	2.336989296	4.739479454	3.091584604	8.012943755	8.469635231	1.206437094	1.765685811	5.06405694	1.251627709	3.378675489	4.586315719	8.302698005	1.954409475	2.152600848	2.853467016	10.82717391	0.898578683	2.877134792	0.225140982	1.251122444	0.717480422	2.688125937	8.070378092	8.567843259	4.780468643	2.207585386	18.62520251	25.77262397	47.08268267	29.61924565	15.82414666	10.89997647	37.91559081	16.50870222	20.86145215	5.289694462	51.7094438	5.917382046	8.286196904	9.755551588	10.79595847	19.85234675	9.626611109	8.925940047	27.68705216	10.72026724	26.56260701	14.60707788	54.04618814	34.47649783	5.979244357	10.67298188	45.15340113	13.71785146	16.01370621	2.247425382	19.68898305	12.49594124	11.81338983	6.571198093	22.53631291	66.62751864	16.83408051	8.481041737	9.998442821	5.602213053	6.276374024	6.05380757	4.388164032	5.999048128	8.169442026	5.942382519	9.769224701	9.990560021	4.645745849	6.299669507	9.065935049	6.192089767	6.964637829	2.474335676	2.95960084	4.30487395	1.153555444	4.447852745	9.836930605	6.152829181	11.81191281	2.836496524	1.420531667	55.49806963	10.39150018	9.766189158	17.67939144	22.2005762	11.94115806	5.626139375	5.021255189	45.19743766	33.05339574	7.166440566	4.610460168	93.58829944	45.55243119	14.59609944	25.92560147	31.64556549	50.12986293	14.94234173	19.12120773
C20_Ceramide	1.194466768	6.050675387	1.320619224	0.812519225	2.219643973	6.296732724	1.03268159	2.141047222	4.424109162	1.345909579	5.341624158	8.055559016	9.956844181	0.786166591	2.490293782	13.28459044	1.960135539	1.108850789	1.461191947	2.339709868	1.076330817	2.8225	2.555886009	0.532445694	0.09004069	0.546068875	1.895292956	7.397681452	2.285082459	12.88003654	1.46724195	11.92338973	8.531396138	1.268687071	17.46059259	22.37854406	18.6826936	6.86356464	2.127847671	4.05030464	1.567186345	3.741383881	4.20697832	0.920276507	3.624607354	0.432534555	0.165380859	2.616024503	0.561525709	0.750574669	2.031821987	4.28486772	5.069282863	3.96090766	8.244017595	1.986510264	1.215152555	3.326370051	0.880385231	1.184663673	1.325901898	10.0480461	0.479038673	0.888643178	3.949525237	11.87678661	0.548048232	4.157580585	0.149027117	1.698956107	2.468753389	2.38918066	2.113701274	8.591201492	3.044001992	3.147176763	3.589910788	16.40271137	16.12538589	9.209560166	3.708059751	17.71408223	56.83614274	60.94173067	5.544869535	13.98541567	35.35858834	4.879451176	11.33458967	26.47264181	20.35660872	17.99913381	13.73542803	5.408324787	47.59854098	23.93398334	13.89715162	21.10501345	97.891339	33.85783009	13.33793307	10.10151153	9.950308017	23.52451093	5.06757173	5.152851497	18.61556962	5.360227848	32.34620253	2.807188291	8.715702045	20.26720633	17.15503956	2.038493356	10.41072089	2.388122354	1.880280526	1.745830766	3.738858865	4.997141492	10.47472904	5.388833333	5.729850638	9.734666667	5.218789577	2.510480393	6.052913063	6.657123427	6.515707464	2.468121819	1.032621951	2.845447154	1.608795069	5.872708068	32.18146628	2.18516129	10.08153959	1.661878152	1.839284718	5.058052888	7.575720352	17.90097811	13.34628859	18.07289627	23.50079615	6.341709555	10.05075016	8.570594922	9.614799621	4.827817339	2.876064625	71.00761603	18.65359291	26.00018565	11.95935272	43.01624856	50.38774904	19.93225453	5.080825434
C24_Ceramide	4.394554238	16.77990158	3.502401796	2.300089419	6.511428571	10.48436364	3.120938416	6.392615385	9.283368421	3.832870027	27.6640435	18.88971391	21.51863532	2.598404086	6.716342724	20.92501707	4.985171536	5.251770389	2.529788541	4.52743152	2.63159009	6.844924893	2.445470832	2.856994121	0.360566775	0.78146672	4.315885373	16.22199445	4.417417752	16.25335204	5.049229133	24.55488215	17.99905138	5.572571429	38.09476923	41.38779841	27.67365967	14.0746888	5.026313426	12.92323774	3.036742831	5.809421067	8.90777897	1.902181968	8.444276117	0.697959471	0.309813802	4.108132218	2.022395652	1.44518667	4.066542578	8.119221943	6.745156493	6.110341917	11.46542355	4.385608593	4.03373923	5.360311209	1.923556654	1.890215005	3.7900115	19.78788079	1.142592652	3.462806289	5.590404387	15.77292666	1.453602534	7.26253427	0.248703549	5.989718986	1.382733	3.354242632	4.60459647	11.24813507	9.171364103	15.21230769	14.56	31.1808	25.55076923	21.82564103	9.291692308	33.08307692	72.66461538	105.6402797	11.86202429	43.42153846	47.88340081	13.4017094	39.73194389	46.34379084	40.55549869	35.21154309	26.87049393	17.80170223	36.01679667	53.29314629	34.81245847	48.31521505	150.8020348	65.74634068	33.22170158	24.20534983	13.09339918	35.65597306	9.336375309	10.2697626	38.81955556	11.71370667	78.14162963	9.134844444	28.95279772	41.94773333	37.59466667	7.24040404	20.21737947	5.065710872	5.105803129	3.658910089	6.519209486	14.1484492	30.9445614	10.48584615	22.58481715	22.4933687	9.728819975	8.635656516	14.6701564	10.05262685	14.5039053	4.66333979	2.98879426	4.383564914	1.87786988	10.6601509	29.38579029	4.920201446	14.67032541	2.664744299	3.865458183	15.64740125	14.42341463	53.61740053	25.58769231	34.70769231	40.42004963	18.09025469	12.78538991	34.77896885	25.19108806	13.08665677	9.539844567	75.48246914	31.44760889	40.68724938	26.38222222	74.03011448	69.51142029	47.34539339	17.30182946
C24_1_Ceramide	2.505566131	8.098612421	1.521970811	1.278720553	1.421940874	5.634419257	2.991093789	5.027542373	3.998513232	4.145314631	9.002524967	7.138286518	5.532677596	1.443461398	3.013044451	15.84904275	4.301569645	1.858689023	1.372591769	5.503831192	2.876324077	4.619038076	5.15329658	4.210214924	0.526633663	0.535466094	6.32423756	29.37476592	6.186576355	15.70905172	1.816915845	15.30211505	10.82132558	2.556298201	22.64256121	26.81355932	18.41739428	5.675884528	3.846876098	10.97270173	9.07118783	9.320467021	8.264261857	3.380385772	8.748178175	1.544454494	1.316584158	14.03026553	5.171079899	1.927051599	4.040311174	8.943463096	14.88312527	11.55330227	12.30696629	3.524212382	6.404972508	5.810393258	1.936797753	3.16343633	3.858978164	40.25450745	1.475655431	5.307112069	14.39490969	16.9180624	2.968136489	14.08355911	0.325942386	11.49046222	1.24196101	3.435369458	5.749876847	22.54588154	8.990772277	6.390653465	10.1420297	21.18313663	12.39363861	49.15686469	7.904615718	22.22774077	21.70942574	79.14271827	3.375867639	12.77025044	45.58863992	7.370484048	22.44984668	20.5325938	49.45641725	15.8469506	12.69087724	15.18111234	13.93138514	32.29759455	17.08841677	40.86539641	130.0262613	62.9997138	16.18995818	10.43339604	6.472369209	21.3337817	5.311354232	5.943839743	13.48915361	7.442838871	42.84789969	7.810815047	18.4789197	20.30811912	20.56847962	4.976585269	15.11438685	4.611671657	2.498952646	2.042018551	4.561931374	5.550037804	7.699098028	6.11684322	10.27120496	18.02980713	12.57794395	3.633750116	10.32943814	6.320662028	6.212622721	4.553126839	7.01738477	7.556272545	2.379036334	10.44908062	46.48314607	4.471235955	33.24651685	3.215696373	3.825352274	11.2014236	9.787693794	22.79829976	10.58745668	15.74168317	14.74882785	6.956193898	4.763928005	13.45961778	18.24396833	8.516971131	6.084787302	94.53979101	8.64813442	25.45747126	8.73685402	54.53369051	23.00228431	24.7694315	5.967704892
18_0_SM	0.536059204	4.055501	0.429659574	0.955912331	0.673156056	1.769881423	0.138226508	0.941176326	0.118386103	0.289077976	0.562384506	0.776505648	1.148215525	0.04189235	0.173869743	20.49407145	0.068441036	0.394201561	0.099495779	17.21015478	0.787723214	0.94872089	6.002636916	5.112582739	0.287251408	0.124978532	1.00963189	14.34343361	3.109433741	0.544150905	10.74968272	9.100927441	21.20311909	1.057962733	0.149725737	21.41318339	4.641686015	0.92282939	8.349250671	23.51310979	0.933888543	10.41070764	36.25684932	0.941041488	13.25297712	1.671552372	0.050372811	3.398318254	2.622636048	1.99403836	4.891037487	7.812955985	7.959328084	10.80942273	2.345795561	4.850192413	3.100769288	5.153329439	2.422064836	1.846609716	2.321915227	18.0726065	4.895662967	4.042263863	9.507957393	1.290760495	0.803902382	19.77599859	0.046506313	0.730386138	0.047898511	0.629349389	7.213886278	16.60292993	0.682769607	5.831606987	1.908212227	0.74589359	0.707384279	1.782071616	0.141908188	8.25647638	10.1035179	26.11623025	0.808542956	44.61493964	12.13661963	4.258363901	43.44586207	5.198717562	8.672870027	1.921508046	0.528830264	4.248593915	2.327980902	42.04711724	1.320808899	23.27980902	19.69328382	10.97197241	24.584	2.852776012	0.280585387	6.887095855	3.251643733	21.12545093	6.349696	4.337273173	45.346944	0.52658928	6.535561846	7.38700032	26.771976	0.361868058	17.11748906	0.226982384	0.813166458	0.145987392	0.757254253	3.068883205	0.048661772	0.252274067	2.392308931	15.2925818	19.07503004	0.298442535	7.475489989	2.121601172	0.976998737	3.040673809	1.083928724	22.02603596	0.443358212	19.87786081	3.883549065	0.409380491	8.904953271	2.060706543	4.367669719	0.395351805	2.771296794	9.728467399	0.507850153	1.463077729	1.78276422	11.90667085	0.856938531	1.468104075	2.573092089	0.572557465	3.858178638	3.9924416	1.614283776	26.64250027	0.867482984	43.19632291	0.609512181	10.90732281	0.544461276
18_1_SM	0.035002211	0.386840504	0.042471186	0.06166742	0.039354136	0.100588679	0.015566553	0.059465567	NA	0.030300926	0.052480944	0.065927978	0.143078363	NA	0.002129474	0.799608877	0.012267215	0.036244516	0.006574143	0.406264403	0.07596539	0.100928041	0.524667946	0.45239943	0.020668615	0.014175018	0.106423584	1.337488252	0.389782483	0.047083817	0.507118644	0.575384615	0.693860037	0.118550943	NA	1.153524904	0.163074074	0.068515152	0.615075075	1.801853746	0.082045923	0.748863738	2.169402062	0.081034794	0.387118088	0.171677697	0.005430761	0.27962072	0.263779825	0.15705045	0.233205009	0.448848878	0.551171654	0.683995049	0.191903008	0.252216939	0.076433771	0.146785714	0.181726333	0.095603853	0.150867144	1.013306522	0.212935855	0.239591067	0.727911833	0.19961949	0.044656216	0.543549884	0.004197897	0.063911241	0.003134694	0.035473782	0.319335557	1.792982787	0.098813843	0.359580723	0.149756731	0.038522039	0.098329282	0.301646749	0.009575791	0.499189104	1.072982294	0.991396543	0.100039922	1.626317444	1.054966447	0.363512066	1.881856651	0.248838607	0.414261061	0.11703717	0.036552447	0.135511509	0.494315263	1.212471399	0.097584392	1.266877167	0.584473392	0.724018635	0.9176204	0.185165469	0.044591839	0.351675717	0.317697387	0.352110805	0.734174634	0.531987389	1.294817081	0.033988948	0.826588224	0.274714799	1.568046845	0.037794691	1.186873422	0.020652816	0.087254237	0.011175392	0.071203256	0.103560716	NA	0.03124783	0.313937462	1.418919221	0.652686981	0.022929527	0.385425101	0.091567568	0.081865909	0.112882255	0.122982216	0.940639175	0.051950695	1.364371853	0.390295489	0.046353383	2.846097744	0.338093229	0.315019425	0.014259581	0.210727108	0.436161514	0.031031323	0.10038638	0.159790061	0.505655686	0.083027933	0.106229028	0.140860648	0.054561213	0.289810237	0.3589669	0.153616031	1.663239261	0.047351558	2.31052645	0.039488729	0.48260708	0.062452961
16_0_SM	3.687994809	11.87416762	3.859104478	8.615036744	7.684729064	7.087147335	3.350389321	6.273381295	1.809415625	5.509302903	2.944724653	8.426080126	13.04199005	1.02458783	1.972788688	38.32639302	2.099243061	3.721648064	2.278665545	21.02872319	8.607262303	12.41167224	14.77750602	6.074351882	2.01160872	1.767059228	9.117795918	72.4353125	14.76586607	7.479441964	15.23330715	20.05970149	35.83808096	9.174384236	1.493333333	22.54527413	8.999345978	7.641791045	25.50613741	41.34475939	11.3312652	24.42778464	34.47686734	7.123406145	21.25895979	6.48145377	1.428881103	14.67582593	19.69913753	6.940317753	11.71741958	18.03126881	44.09084365	13.79685366	11.99799	12.15129412	7.397648936	8.59465625	8.761840909	8.407	9.075481132	55.72081395	6.2301875	8.06921875	25.39257143	12.12438095	6.025923345	27.85891071	0.483943323	12.18339666	0.651606383	7.206	11.35588393	47.28189369	0.73662359	4.879331868	2.006892308	0.439532308	0.824123077	5.358495726	0.276996923	9.489902098	6.122057143	26.58282517	0.804845344	20.73773756	8.41794332	3.561025641	47.02772093	3.117315738	12.90487299	2.450009302	0.45873554	2.660079891	4.618922361	29.81536744	0.972502326	18.27125581	16.48246154	10.46444651	20.38528541	2.166552073	0.249941851	7.103973514	1.378262822	6.772578112	3.181023369	2.174873445	39.77633991	1.002875873	4.814679584	5.849397997	18.70612443	5.666460152	25.60812956	1.691670679	11.50763828	2.610945274	9.877061469	11.61866126	0.558980184	3.928057554	16.15284821	43.34408335	24.33307148	2.09825449	14.54879449	4.820659971	12.89501591	21.74493387	15.36396321	28.98065217	6.483513887	33.17399311	9.62001	3.491307	50.8023	7.808449675	10.9526412	0.097013888	4.55612758	8.525411141	0.552276923	1.49127033	1.352861538	8.210739958	0.677047523	1.392994503	2.007883995	0.307738228	1.956766421	2.712269499	1.429347059	15.72989863	0.579465024	41.72722307	0.388904316	8.550492392	0.820429544
24_0_SM	0.278040965	3.100578035	0.282927746	0.513989182	0.431908256	0.549331248	0.071980018	0.351415094	0.040443562	0.199700716	0.184735317	0.685147218	1.377438706	0.041133158	0.097677398	11.83655577	0.012727603	0.235011519	0.073570932	7.474463152	0.744958655	0.609369673	2.296101054	2.111604045	0.211411379	0.185324718	0.947660099	8.384159483	2.295900152	0.368036799	8.077821722	5.724144064	8.781059673	0.49095026	0.056226415	22.29668185	2.77724414	0.622062567	2.450713878	5.489267909	0.304001687	4.395920825	14.42205256	0.407043457	6.769394047	0.725872117	0.103443209	1.301123931	2.659502061	1.89158496	1.917669584	5.676472051	8.144503377	2.572550463	1.494775862	7.500760649	1.105603448	2.017726293	1.392055251	0.916729526	1.401821731	20.77506014	1.791998922	3.382691172	5.830857529	2.618112762	0.579776766	9.612255233	0.064382908	1.456486057	0.10723275	0.545560432	2.140025743	8.005177991	0.364208281	8.253031579	1.866421053	0.461642779	0.748136842	0.844159064	0.216559737	5.445557895	14.52985263	16.12907177	0.956901939	38.82672446	4.054120776	2.830128655	38.57470313	2.431342151	6.597977885	2.454309375	0.425520993	2.060308456	10.72284231	27.3396375	0.958382419	10.28959615	11.91426923	7.56324	25.70757955	2.257471467	0.204976675	2.022662396	0.732325757	8.508122738	1.828817866	1.483285757	50.23259553	0.664543697	1.840489864	9.894783127	16.456366	0.511156615	4.47769647	0.309432687	1.208313499	0.12725289	0.207133867	2.8423196	0.038076134	0.152689858	2.249056604	6.747169811	3.478439721	0.143246686	2.349365756	0.746701885	1.059242824	0.147197145	0.553351385	4.153551136	0.386128181	25.19983924	3.055887931	0.316202586	4.90887931	1.360948914	6.978098551	0.145278179	2.223638511	8.795272595	0.424061842	1.712715789	2.235455348	17.28061364	2.219209239	1.515253807	2.112075	0.362477736	2.103489329	1.323031266	1.516082025	5.731893201	0.979053209	21.34467855	0.546874528	9.246613641	0.699694164
24_1_SM	0.213057862	4.756843157	0.260374573	0.554416862	0.36	0.935064935	0.189788018	0.512650177	0.054977869	0.498598757	0.161731594	0.492119488	0.755171171	0.036658628	0.083254623	12.65161731	0.029585866	0.229351353	0.133051866	14.37278144	1.181942734	1.219267241	5.599275046	4.017431071	0.258725613	0.111031662	1.91209266	19.47684602	3.316412226	0.635913995	7.290916286	10.23347179	14.31055901	0.768783673	0.109891166	15.64693554	1.848249277	0.504226044	4.037600543	9.037054188	1.510888519	9.371696964	29.90107759	0.982792295	11.94195729	1.126254181	0.222304241	2.953217638	4.747292331	2.390582792	2.604462793	9.022831788	10.61984241	4.967791109	1.490933468	5.431451613	1.716107584	1.977387853	1.819227685	1.587002268	1.517988246	35.05180983	1.548812374	3.005163182	9.530660377	2.47568205	0.917255382	10.56100204	0.056836782	1.846942235	0.049324867	0.613053289	2.749724312	18.30054522	0.73662359	4.879331868	2.006892308	0.439532308	0.824123077	5.358495726	0.276996923	9.489902098	6.122057143	26.58282517	0.804845344	20.73773756	8.41794332	3.561025641	47.02772093	3.117315738	12.90487299	2.450009302	0.45873554	2.660079891	4.618922361	29.81536744	0.972502326	18.27125581	16.48246154	10.46444651	20.38528541	2.166552073	0.249941851	7.103973514	1.378262822	6.772578112	3.181023369	2.174873445	39.77633991	1.002875873	4.814679584	5.849397997	18.70612443	0.54116767	12.67248586	0.130909091	0.837602026	0.200027341	0.838956522	2.097478992	0.023614655	0.372985866	2.051462666	12.29272572	7.231863442	0.092872194	4.833679834	1.104572148	0.560624597	1.295217488	1.825272091	17.41810345	0.709977043	25.97280049	5.580816532	0.375992238	10.4283871	1.290854185	5.331419067	0.097013888	4.55612758	8.525411141	0.552276923	1.49127033	1.352861538	8.210739958	0.677047523	1.392994503	2.007883995	0.307738228	1.956766421	2.712269499	1.429347059	15.72989863	0.579465024	41.72722307	0.388904316	8.550492392	0.820429544
SA	10.58695652	14.66666667	33.83333333	5.672131148	16.78571429	17.12727273	5.64516129	7	7.070175439	4.293103448	9.5	5.385964912	10.2	15.33846154	24.73684211	8.268292683	7	7.779661017	2.827586207	3.275259972	17.81049755	22.68815303	11.11733983	23.93640872	8.31457753	23.23285331	4.741524029	8.169942876	9.226256983	38.12238128	2.736842105	7.846153846	24.43478261	6.457142857	4.933333333	4.206896552	17.72727273	6.242424242	40.19607843	3.594594595	13.20460542	9.409716646	6.294195251	3.207618734	4.357519789	4.06947718	3.36640539	9.79301722	8.629979918	8.492821941	5.914643852	7.074670803	6.200375439	6.316384736	9.53016129	3.714104997	21.34746054	5.025285618	2.764607771	7.399193548	7.482958004	14.93604651	7.553343414	7.143942039	7.27849162	42.37243948	5.138200027	50.35998603	4.51284309	15.47524664	19.00870676	32.90698324	20.29776536	11.33613746	50.53533333	10.92675	26.105625	51.4794	54.6975	304.7722222	66.1565625	29.75	59.262	31.58909091	55.24105263	56.7	92.69473684	14.74277778	24.395	14.94418605	10.16076923	21.7175	19.845	95.55	125.7738462	19.992	47.21612903	34.14384615	64.53461538	30.192	14.71272727	11.40847826	55.59944444	18.49909091	16.26333333	7.453463415	17.51	20.23	16.15	2.8336875	12.99846154	21.063	27.3328125	14.32075472	8.829787234	1.377419355	20.78431373	10.09259259	14.26086957	7.960784314	43.33333333	15.9375	7.37704918	37.24137931	5.350877193	8.966101695	3.769230769	8.558823529	10.06521739	6.597014925	3.667579156	7.204432718	7.13622806	7.072537093	9.293387097	9.648548387	27.55459677	7.653599543	3.683350656	91.56567568	32.65243902	22.40482759	57.9009375	56.355	55.39258065	9.119727273	9.701086957	24.82772727	16.065	12.44675676	20.20097561	67.43333333	47.2668	16.50133333	24.79702703	33.10363636	24.05869565	20.64810811	21.08790698
SO	25.43478261	29.74358974	36.16666667	9.836065574	43.03571429	36.54545455	12.83870968	20.46875	9.543859649	8.275862069	55.17241379	17.71929825	35.77777778	26.46153846	24.73684211	38.53658537	19.82758621	27.11864407	9.810344828	16.73529412	40.71428571	114.3	47.38636364	5.341463415	1.786666667	43.58490566	41.63265306	26.21875	169.875	371.875	5.684210526	18.84615385	53.47826087	11.28571429	13.75	22.5862069	76.06060606	13.66666667	19.80392157	7.972972973	120.3409091	39.7826087	37	10.34375	47.04545455	17.71153846	12.97674419	63.40909091	15.1744186	11.65384615	28.39285714	33.85227273	32.60869565	55.24390244	29.79	16.47058824	17.0106383	124.375	19.09090909	13.5	138.9622642	76.74418605	19.5	8.5625	49.33333333	184.3333333	19.5	39.375	0.541304348	39.57446809	10.53191489	51.3	79.875	55.11627907	17.45333333	19.89	98.91875	127.092	177.225	156.6833333	74.52375	77.13363636	211.14	123.3272727	119.3131579	74.76	368.9	32.06388889	46.55875	50.56116279	22.33538462	66.3425	51.24	53.97	46.27269231	78.183	135.8903226	92.45384615	280.1076923	126.48	38.29636364	38.41630435	216.1833333	77.45818182	72.49083333	31.17219512	108.8	66.32266667	60.605	9.6613125	80.64538462	126.378	108.215625	33.77358491	19.14893617	2.709677419	20	28.14814815	24.7826087	21.96078431	45.78947368	24.6875	33.60655738	46.55172414	13.35087719	18.13559322	14	31.17647059	33.26086957	19.10447761	22.9125	36.9	8.608695652	44.69387755	119.1	141.9	38.7	67.15909091	16.29069767	295.2486486	89.68536585	55.64275862	82.779375	81.7275	138.1935484	34.56409091	34.76869565	146.2077273	110.25	36.85783784	49.71878049	380.8	228.48	77.588	110.9594595	148.2090909	180.0521739	96.00405405	106.2697674
MS_METABOLITE_DATA_END
#METABOLITES
METABOLITES_START
metabolite_name	annotation	HMDB_ID
C14_Ceramide	Cer(d18:1/14:0)	HMDB0011773
C16_Ceramide	Cer(d18:1/16:0)	HMDB0004949
C18_Ceramide	Cer(d18:1/18:0)	HMDB0004950
C18_1_Ceramide	Cer(d18:1/18:1)	HMDB0011774
C20_Ceramide	Cer(d18:1/20:0)	HMDB0004951
C24_Ceramide	Cer(d18:1/24:0)	HMDB0004956
C24_1_Ceramide	Cer(d18:1/24:1)	HMDB0004953
18_0_SM	SM(d18:1/18:0)	HMDB0001348
18_1_SM	SM(d18:1/18:1)	HMDB0012101
16_0_SM	SM(d18:1/16:0)	HMDB0010169
24_0_SM	SM(d18:1/24:0)	HMDB0011697
24_1_SM	SM(d18:1/24:1)	HMDB0012107
SA	Sphinganine	HMDB0000269
SO	Sphingosine	HMDB0000252
METABOLITES_END
#END