#METABOLOMICS WORKBENCH emashin_20250314_081717 DATATRACK_ID:5722 STUDY_ID:ST003805 ANALYSIS_ID:AN006255 PROJECT_ID:PR002379
VERSION             	1
CREATED_ON             	March 14, 2025, 10:22 am
#PROJECT
PR:PROJECT_TITLE                 	Epigenetic changes, neuronal dysregulation and behavioral abnormalities in
PR:PROJECT_TITLE                 	Zmym2+/- mutant mice, a genetic animal model of schizophrenia and
PR:PROJECT_TITLE                 	neurodevelopmental disorders
PR:PROJECT_SUMMARY               	Loss-of-function mutations in ZMYM2 are associated with an increased risk for
PR:PROJECT_SUMMARY               	schizophrenia (SCZ) and neurodevelopmental disorders (NDD). ZMYM2 interacts with
PR:PROJECT_SUMMARY               	proteins that regulate histone modifications and gene expression, but its
PR:PROJECT_SUMMARY               	functions in the brain are unclear. In this multi-omics study, we found that
PR:PROJECT_SUMMARY               	Zmym2 heterozygous knockout in mice leads to widespread disturbance of gene
PR:PROJECT_SUMMARY               	expression and alterations in diverse molecular pathways, including those
PR:PROJECT_SUMMARY               	related to histone modifications and neuronal activity, particularly in neurons.
PR:PROJECT_SUMMARY               	Proteomic analysis of synapses uncovered dysregulation in lipid metabolism and
PR:PROJECT_SUMMARY               	neurofilament pathways. In neurophysiologic and behavioral tests, Zmym2+/-
PR:PROJECT_SUMMARY               	mutant mice exhibit abnormal EEG patterns and locomotor activity. Our findings
PR:PROJECT_SUMMARY               	underscore the critical role of ZMYM2 in brain development and function and
PR:PROJECT_SUMMARY               	establish Zmym2 mutant mice as a useful genetically valid animal model for SCZ
PR:PROJECT_SUMMARY               	and NDD.
PR:INSTITUTE                     	Broad Institute
PR:LAST_NAME                     	Mashin
PR:FIRST_NAME                    	Eivgeni
PR:ADDRESS                       	300 Binney St., Cambridge, Massachusetts, 02142, USA
PR:EMAIL                         	emashin@broadinstitute.org
PR:PHONE                         	6177147061
PR:CONTRIBUTORS                  	Wei-Chao Huang, Kira A. Perzel Mandell, Sameer Aryal, Bryan J. Song, Antia
PR:CONTRIBUTORS                  	Valle-Tojeiro, Nathaniel Goble, Chuhan Geng, Ahmet S. Asan, Xiao-Man Liu,
PR:CONTRIBUTORS                  	Courtney Dennis, Lucas Dailey, Amy Deik, Lucia Inunciaga, Eivgeni Mashin, Zohreh
PR:CONTRIBUTORS                  	Farsi, Yining Wang, Jen Q. Pan, Clary B. Clish, Hasmik Keshishian, Steven A.
PR:CONTRIBUTORS                  	Carr, Morgan Sheng
#STUDY
ST:STUDY_TITLE                   	Epigenetic changes, neuronal dysregulation and behavioral abnormalities in
ST:STUDY_TITLE                   	Zmym2+/- mutant mice, a genetic animal model of schizophrenia and
ST:STUDY_TITLE                   	neurodevelopmental disorders
ST:STUDY_SUMMARY                 	Loss-of-function mutations in ZMYM2 are associated with an increased risk for
ST:STUDY_SUMMARY                 	schizophrenia (SCZ) and neurodevelopmental disorders (NDD). ZMYM2 interacts with
ST:STUDY_SUMMARY                 	proteins that regulate histone modifications and gene expression, but its
ST:STUDY_SUMMARY                 	functions in the brain are unclear. In this multi-omics study, we found that
ST:STUDY_SUMMARY                 	Zmym2 heterozygous knockout in mice leads to widespread disturbance of gene
ST:STUDY_SUMMARY                 	expression and alterations in diverse molecular pathways, including those
ST:STUDY_SUMMARY                 	related to histone modifications and neuronal activity, particularly in neurons.
ST:STUDY_SUMMARY                 	Proteomic analysis of synapses uncovered dysregulation in lipid metabolism and
ST:STUDY_SUMMARY                 	neurofilament pathways. In neurophysiologic and behavioral tests, Zmym2+/-
ST:STUDY_SUMMARY                 	mutant mice exhibit abnormal EEG patterns and locomotor activity. Our findings
ST:STUDY_SUMMARY                 	underscore the critical role of ZMYM2 in brain development and function and
ST:STUDY_SUMMARY                 	establish Zmym2 mutant mice as a useful genetically valid animal model for SCZ
ST:STUDY_SUMMARY                 	and NDD.
ST:INSTITUTE                     	Broad Institute
ST:LAST_NAME                     	Mashin
ST:FIRST_NAME                    	Eivgeni
ST:ADDRESS                       	300 Binney St., Cambridge, Massachusetts, 02142, USA
ST:EMAIL                         	emashin@broadinstitute.org
ST:PHONE                         	6177147061
#SUBJECT
SU:SUBJECT_TYPE                  	Mammal
SU:SUBJECT_SPECIES               	Mus musculus
SU:TAXONOMY_ID                   	10090
SU:GENOTYPE_STRAIN               	Zmym2+/- mice (C57BL/6NJ-Zmym2em1(IMPC)J /Mmjax; #051239-JAX)
SU:AGE_OR_AGE_RANGE              	1-5 Months
SU:GENDER                        	Male and female
SU:ANIMAL_ANIMAL_SUPPLIER        	Jackson Laboratory
#SUBJECT_SAMPLE_FACTORS:         	SUBJECT(optional)[tab]SAMPLE[tab]FACTORS(NAME:VALUE pairs separated by |)[tab]Raw file names and additional sample data
SUBJECT_SAMPLE_FACTORS           	-	101304_1	Sample source:mouse cortex | Sex:M | Genotype:WT | Age:1M | Brain_region:CTX | Mice_:Zmym2	Tissue_weight_(g)=0.063; RAW_FILE_NAME(HP)=B0121_SHE_AKAP11_3rd_Set_HP-101304_1; RAW_FILE_NAME(CN)=B0121_SHE_AKAP11_3rd_Set_CN-101304_1; RAW_FILE_NAME(CP)=B0121_SHE_AKAP11_3rd_Set_CP-101304_1; RAW_FILE_NAME(HN)=B0121_SHE_AKAP11_3rd_Set_Rerun_HN-101304_1
SUBJECT_SAMPLE_FACTORS           	-	101304_2	Sample source:mouse cortex | Sex:M | Genotype:WT | Age:1M | Brain_region:CTX | Mice_:Zmym2	Tissue_weight_(g)=0.096; RAW_FILE_NAME(HP)=B0109_SHE_AKAP11_3rd_Set_HP-101304_2; RAW_FILE_NAME(CN)=B0109_SHE_AKAP11_3rd_Set_CN-101304_2; RAW_FILE_NAME(CP)=B0109_SHE_AKAP11_3rd_Set_CP-101304_2; RAW_FILE_NAME(HN)=B0109_SHE_AKAP11_3rd_Set_Rerun_HN-101304_2
SUBJECT_SAMPLE_FACTORS           	-	109527_2	Sample source:mouse cortex | Sex:M | Genotype:WT | Age:1M | Brain_region:CTX | Mice_:Zmym2	Tissue_weight_(g)=0.077; RAW_FILE_NAME(HP)=B0127_SHE_AKAP11_3rd_Set_HP-109527_2; RAW_FILE_NAME(CN)=B0127_SHE_AKAP11_3rd_Set_CN-109527_2; RAW_FILE_NAME(CP)=B0127_SHE_AKAP11_3rd_Set_CP-109527_2; RAW_FILE_NAME(HN)=B0127_SHE_AKAP11_3rd_Set_Rerun_HN-109527_2
SUBJECT_SAMPLE_FACTORS           	-	109527_3	Sample source:mouse cortex | Sex:M | Genotype:WT | Age:1M | Brain_region:CTX | Mice_:Zmym2	Tissue_weight_(g)=0.067; RAW_FILE_NAME(HP)=B0094_SHE_AKAP11_3rd_Set_HP-109527_3; RAW_FILE_NAME(CN)=B0094_SHE_AKAP11_3rd_Set_CN-109527_3; RAW_FILE_NAME(CP)=B0094_SHE_AKAP11_3rd_Set_CP-109527_3; RAW_FILE_NAME(HN)=B0094_SHE_AKAP11_3rd_Set_Rerun_HN-109527_3
SUBJECT_SAMPLE_FACTORS           	-	109528_2	Sample source:mouse cortex | Sex:M | Genotype:WT | Age:1M | Brain_region:CTX | Mice_:Zmym2	Tissue_weight_(g)=0.079; RAW_FILE_NAME(HP)=B0107_SHE_AKAP11_3rd_Set_HP-109528_2; RAW_FILE_NAME(CN)=B0107_SHE_AKAP11_3rd_Set_CN-109528_2; RAW_FILE_NAME(CP)=B0107_SHE_AKAP11_3rd_Set_CP-109528_2; RAW_FILE_NAME(HN)=B0107_SHE_AKAP11_3rd_Set_Rerun_HN-109528_2
SUBJECT_SAMPLE_FACTORS           	-	109530_1	Sample source:mouse cortex | Sex:M | Genotype:HET | Age:1M | Brain_region:CTX | Mice_:Zmym2	Tissue_weight_(g)=0.075; RAW_FILE_NAME(HP)=B0120_SHE_AKAP11_3rd_Set_HP-109530_1; RAW_FILE_NAME(CN)=B0120_SHE_AKAP11_3rd_Set_CN-109530_1; RAW_FILE_NAME(CP)=B0120_SHE_AKAP11_3rd_Set_CP-109530_1; RAW_FILE_NAME(HN)=B0120_SHE_AKAP11_3rd_Set_Rerun_HN-109530_1
SUBJECT_SAMPLE_FACTORS           	-	109530_2	Sample source:mouse cortex | Sex:M | Genotype:HET | Age:1M | Brain_region:CTX | Mice_:Zmym2	Tissue_weight_(g)=0.079; RAW_FILE_NAME(HP)=B0093_SHE_AKAP11_3rd_Set_HP-109530_2; RAW_FILE_NAME(CN)=B0093_SHE_AKAP11_3rd_Set_CN-109530_2; RAW_FILE_NAME(CP)=B0093_SHE_AKAP11_3rd_Set_CP-109530_2; RAW_FILE_NAME(HN)=B0093_SHE_AKAP11_3rd_Set_Rerun_HN-109530_2
SUBJECT_SAMPLE_FACTORS           	-	109530_3	Sample source:mouse cortex | Sex:M | Genotype:HET | Age:1M | Brain_region:CTX | Mice_:Zmym2	Tissue_weight_(g)=0.076; RAW_FILE_NAME(HP)=B0097_SHE_AKAP11_3rd_Set_HP-109530_3; RAW_FILE_NAME(CN)=B0097_SHE_AKAP11_3rd_Set_CN-109530_3; RAW_FILE_NAME(CP)=B0097_SHE_AKAP11_3rd_Set_CP-109530_3; RAW_FILE_NAME(HN)=B0097_SHE_AKAP11_3rd_Set_Rerun_HN-109530_3
SUBJECT_SAMPLE_FACTORS           	-	109530_4	Sample source:mouse cortex | Sex:M | Genotype:HET | Age:1M | Brain_region:CTX | Mice_:Zmym2	Tissue_weight_(g)=0.063; RAW_FILE_NAME(HP)=B0096_SHE_AKAP11_3rd_Set_HP-109530_4; RAW_FILE_NAME(CN)=B0096_SHE_AKAP11_3rd_Set_CN-109530_4; RAW_FILE_NAME(CP)=B0096_SHE_AKAP11_3rd_Set_CP-109530_4; RAW_FILE_NAME(HN)=B0096_SHE_AKAP11_3rd_Set_Rerun_HN-109530_4
SUBJECT_SAMPLE_FACTORS           	-	109530_5	Sample source:mouse cortex | Sex:M | Genotype:HET | Age:1M | Brain_region:CTX | Mice_:Zmym2	Tissue_weight_(g)=0.089; RAW_FILE_NAME(HP)=B0106_SHE_AKAP11_3rd_Set_HP-109530_5; RAW_FILE_NAME(CN)=B0106_SHE_AKAP11_3rd_Set_CN-109530_5; RAW_FILE_NAME(CP)=B0106_SHE_AKAP11_3rd_Set_CP-109530_5; RAW_FILE_NAME(HN)=B0106_SHE_AKAP11_3rd_Set_Rerun_HN-109530_5
#COLLECTION
CO:COLLECTION_SUMMARY            	The detailed procedure of brain perfusion and dissection was described
CO:COLLECTION_SUMMARY            	previously31. In brief, mice were anesthetized with isoflurane, and transcardial
CO:COLLECTION_SUMMARY            	perfusions were performed with ice-cold HBSS (Life Technologies) to remove blood
CO:COLLECTION_SUMMARY            	from the brain, which was then immediately frozen in liquid nitrogen vapor and
CO:COLLECTION_SUMMARY            	stored at –80°C. Brain dissection was carried out in a cryostat, with all
CO:COLLECTION_SUMMARY            	tools precooled to –20°C. The cerebellum was removed first, and then the
CO:COLLECTION_SUMMARY            	medial prefrontal cortex, dorsal hippocampus, thalamus, somatosensory cortex,
CO:COLLECTION_SUMMARY            	and dorsal striatum, and substantia nigra, were meticulously dissected using
CO:COLLECTION_SUMMARY            	biopsy punch and ophthalmic microscalpel in a cryostat (Leica). The brain
CO:COLLECTION_SUMMARY            	regions were identified using the Allen Brain Atlas, with each excised tissue
CO:COLLECTION_SUMMARY            	stored at –80°C in 1.5ml tubes.
CO:SAMPLE_TYPE                   	Brain cortex
#TREATMENT
TR:TREATMENT_SUMMARY             	NO TREATMENT ADMINISTRED TO THE ANIMALS PRIOR TO SAMPLE COLLECTION
#SAMPLEPREP
SP:SAMPLEPREP_SUMMARY            	Brain tissues (n = 5 per genotype) were homogenized using a Qiagen TissueLyzer
SP:SAMPLEPREP_SUMMARY            	II in water at 1:4 (w:v) (TissueLyser II; Qiagen) and the aqueous homogenate was
SP:SAMPLEPREP_SUMMARY            	subjected to protein precipitation. Samples were prepared for each method using
SP:SAMPLEPREP_SUMMARY            	extraction procedures that are matched for use with the chromatography
SP:SAMPLEPREP_SUMMARY            	conditions: - HILIC-pos: Homogenates (10 μL) samples were extracted with the
SP:SAMPLEPREP_SUMMARY            	addition of nine volumes of 74.9:24.9:0.2 v/v/v acetonitrile/methanol/formic
SP:SAMPLEPREP_SUMMARY            	acid containing stable isotope-labeled internal standards (valine-d8, Isotec;
SP:SAMPLEPREP_SUMMARY            	and phenylalanine-d8, Cambridge Isotope Laboratories). The samples were
SP:SAMPLEPREP_SUMMARY            	centrifuged (10 min, 9,000g, 4°C), and the supernatants (10 μL)injected
SP:SAMPLEPREP_SUMMARY            	directly onto column. - C8-pos: Homogenates (10 μL) were extracted using 190
SP:SAMPLEPREP_SUMMARY            	μL isopropanol containing
SP:SAMPLEPREP_SUMMARY            	1-dodecanoyl-2-tridecanoyl-sn-glycero-3-phosphocholine as an internal standard
SP:SAMPLEPREP_SUMMARY            	(Avanti Polar Lipids; Alabaster, AL). After centrifugation (10 min, 9,000g,
SP:SAMPLEPREP_SUMMARY            	ambient temperature), supernatants (2 μl) were injected directly onto column. -
SP:SAMPLEPREP_SUMMARY            	C18-neg: Homogenates (30 μL) were extracted using 90 μl methanol containing
SP:SAMPLEPREP_SUMMARY            	15R-15-methyl ProstaglandinA2,15R-15-methyl ProstaglandinF2α, 15S-15-methyl
SP:SAMPLEPREP_SUMMARY            	ProstaglandinD2, 15S-15-methyl Prostaglandin E1, and 15S-15-methyl Prostaglandin
SP:SAMPLEPREP_SUMMARY            	E2 as internal standards (Cayman Chemical Co.) and centrifuged (10 min, 9,000g,
SP:SAMPLEPREP_SUMMARY            	4°C). The supernatants (10 μL) were injected onto column. - HILIC-neg:
SP:SAMPLEPREP_SUMMARY            	Homogenates (30 μL) were extracted with the addition of four volumes of 80%
SP:SAMPLEPREP_SUMMARY            	methanol containing inosine-15N4, thymine-d4 and glycocholate-d4 internal
SP:SAMPLEPREP_SUMMARY            	standards (Cambridge Isotope Laboratories). The samples were centrifuged (10
SP:SAMPLEPREP_SUMMARY            	min, 9,000g, 4°C) and the supernatants 10 μL) were injected directly onto
SP:SAMPLEPREP_SUMMARY            	column.
#CHROMATOGRAPHY
CH:CHROMATOGRAPHY_TYPE           	Reversed phase
CH:INSTRUMENT_NAME               	Shimadzu Nexera X2
CH:COLUMN_NAME                   	Waters ACQUITY UPLC BEH C8 (100 x 2.1mm,1.7um)
CH:SOLVENT_A                     	95% water/5% methanol; 10 mM Ammonium acetate; 0.1% Acetic acid
CH:SOLVENT_B                     	100% methanol; 0.1% Acetic acid
CH:FLOW_GRADIENT                 	The column was eluted at a flow rate of 450 µL/min isocratically for 1 minute
CH:FLOW_GRADIENT                 	at 80% mobile phase A, followed by a linear gradient to 80% mobile-phase B over
CH:FLOW_GRADIENT                 	2 minutes, a linear gradient to 100% mobile phase B over 7 minutes, and then 3
CH:FLOW_GRADIENT                 	minutes at 100% mobile-phase B.
CH:FLOW_RATE                     	450 µL/min
CH:COLUMN_TEMPERATURE            	40℃
#ANALYSIS
AN:ANALYSIS_TYPE                 	MS
#MS
MS:INSTRUMENT_NAME               	Thermo Q Exactive Orbitrap
MS:INSTRUMENT_TYPE               	Orbitrap
MS:MS_TYPE                       	ESI
MS:ION_MODE                      	POSITIVE
MS:MS_COMMENTS                   	Raw data were processed using TraceFinder 3.3 software (Thermo Fisher
MS:MS_COMMENTS                   	Scientific; Waltham, MA) and Progenesis QI (Nonlinear Dynamics; Newcastle upon
MS:MS_COMMENTS                   	Tyne, UK). Metabolite identities were confirmed using authentic reference
MS:MS_COMMENTS                   	standards or reference samples.
MS:MS_RESULTS_FILE               	ST003805_AN006255_Results.txt	UNITS:abundances	Has m/z:Yes	Has RT:Yes	RT units:Minutes
#MS_METABOLITE_DATA
MS_METABOLITE_DATA:UNITS	abundances
MS_METABOLITE_DATA_START
Samples	109530_2	109527_3	109530_4	109530_3	109530_5	109528_2	101304_2	109530_1	101304_1	109527_2
Factors	Sample source:mouse cortex | Sex:M | Genotype:HET | Age:1M | Brain_region:CTX | Mice_:Zmym2	Sample source:mouse cortex | Sex:M | Genotype:WT | Age:1M | Brain_region:CTX | Mice_:Zmym2	Sample source:mouse cortex | Sex:M | Genotype:HET | Age:1M | Brain_region:CTX | Mice_:Zmym2	Sample source:mouse cortex | Sex:M | Genotype:HET | Age:1M | Brain_region:CTX | Mice_:Zmym2	Sample source:mouse cortex | Sex:M | Genotype:HET | Age:1M | Brain_region:CTX | Mice_:Zmym2	Sample source:mouse cortex | Sex:M | Genotype:WT | Age:1M | Brain_region:CTX | Mice_:Zmym2	Sample source:mouse cortex | Sex:M | Genotype:WT | Age:1M | Brain_region:CTX | Mice_:Zmym2	Sample source:mouse cortex | Sex:M | Genotype:HET | Age:1M | Brain_region:CTX | Mice_:Zmym2	Sample source:mouse cortex | Sex:M | Genotype:WT | Age:1M | Brain_region:CTX | Mice_:Zmym2	Sample source:mouse cortex | Sex:M | Genotype:WT | Age:1M | Brain_region:CTX | Mice_:Zmym2
PC 12:0/12:0 [iSTD]	49629012	50693546	50336423	49887729	48830986	47937656	48529081	50418023	49784302	48022072
LPC 0:0/14:0	3258	4111	4651	3630	3585	3462	2116	3790	2720	3023
LPC 14:0/0:0	22722	21638	23356	19549	17352	18373	13107	24085	16348	19996
LPC 16:1/0:0	117847	116467	110321	100282	102439	106229	79371	120305	106773	110494
LPC 16:0/0:0	7674365	6957228	7502131	7008545	6328896	7380350	5993011	7545375	7182302	7370718
LPC 17:0/0:0	2228736	2340604	2240263	2297680	2114184	2185627	2076521	2152317	2122272	2155389
LPC 0:0/18:2	22606	23264	23003	16870	20150	25973	22588	26181	23121	22183
LPC 18:2/0:0	50006	57870	52114	48873	46252	53460	47092	53769	55009	61622
LPC 0:0/18:1	834653	654795	756788	710546	731772	819424	733705	860031	851346	796007
LPC 18:1/0:0	1960784	1875268	2007296	1753155	1666468	1882063	1576564	2118471	1949075	1968664
LPC 0:0/18:0	22455	16366	19860	13174	18329	22617	29013	25812	25365	25827
LPC 18:0/0:0	3855403	3458276	3671931	3682766	3370783	3885411	3277383	3920941	3675518	3865377
LPC 19:0/0:0	3665	4738	5470	4614	3486	4702	5370	4660	5633	5361
LPC 0:0/20:4	599735	507098	542295	532788	570392	590291	513214	664566	651599	566976
LPC 0:0/20:3	18969	14411	16608	16836	15617	17714	18123	21076	18375	18294
LPC 20:3/0:0	24217	23233	23964	23467	23657	25840	20389	28136	29552	27275
LPC 0:0/20:2	3151	3233	3822	1667	2609	3756	3471	3313	3606	4452
LPC 20:2/0:0	23404	25388	32295	20746	22463	28511	23216	33267	26307	28711
LPC 0:0/20:1	8259	5692	9281	7002	5237	9761	9956	11921	9125	10195
LPC 20:1/0:0	113281	99685	111099	94179	93202	109119	101211	122071	106605	113672
LPC 20:0/0:0	33820	17031	29512	27317	24426	33661	33194	38576	27749	36991
LPC 0:0/22:6	512028	415402	484005	439232	439770	518897	460551	545365	567090	538787
LPC 0:0/22:4	24108	22252	21212	20566	20309	24845	23015	26179	29043	23631
LPC 22:4/0:0	4518	5156	4438	3885	4256	4589	4138	5084	5391	4572
LPC 22:1/0:0	10937	7398	11801	10289	9454	11461	11069	12262	9031	13047
LPC 22:0/0:0	39811	21850	41477	34869	27695	31798	30898	49676	26171	44180
LPC 23:0/0:0	4625	3062	5994	3017	1664	4276	4297	7350	3806	4596
LPC 24:1/0:0	13310	5788	14291	11932	10325	13391	13776	17491	9137	15552
LPC 24:0/0:0	189892	124724	208520	157829	130833	159113	147393	213246	110960	175918
LPC 26:1/0:0	8525	5516	10665	6785	6888	9280	8369	10973	8134	8391
LPC 26:0/0:0	9225	5791	11495	8691	5610	8337	9112	9300	9363	11733
LPC P-16:0/0:0	17965	17373	18238	18116	16400	18635	20189	20408	24114	20707
LPC O-16:0/0:0	17213	17712	17842	17400	14030	18533	16024	20008	18917	20660
LPC O-18:1/0:0	7632	8049	8314	6275	4446	6877	4643	6279	6470	6588
LPC O-18:0/0:0	9654	7991	9898	11650	7059	11455	9136	12755	8882	12442
LPE 0:0/16:0	9758	9154	10355	9659	7880	9588	8726	9260	8777	11527
LPE 16:0/0:0	154727	166011	154691	162746	132767	156696	120109	164543	147658	150014
LPE 0:0/18:1	88062	68238	89225	80534	74264	91222	85626	104103	81694	93022
LPE 18:1/0:0	118270	120211	120531	114143	105656	118813	97555	127085	115693	123270
LPE 18:0/0:0	744511	709118	703089	777768	658539	726623	567462	730014	682500	743478
LPE 0:0/20:4	279106	258106	272472	277913	267563	291736	230254	308943	277800	285979
LPE 22:6/0:0	750497	684560	759910	735002	693859	804169	663146	843058	766523	794799
PC 28:0	312732	274786	413212	275486	248817	259979	149847	375008	155408	288546
PC 29:0	96582	156593	170415	86668	86207	90046	60718	113664	62941	89292
PC 30:1	501476	573511	549327	468716	442115	482892	313772	587687	364205	510874
PC 30:0	36593758	37353390	41603331	35737624	30644113	33863041	22345664	40941369	25293400	34292194
PC 31:1	287084	498588	493180	251204	228831	276546	191908	317906	210022	279872
PC 31:0	10480312	17651933	17545942	9768428	9181641	10932638	8246490	11248414	9207710	10275618
PC 32:2	807908	1081009	954527	786621	747660	838280	569678	922466	681652	876922
PC 32:1	1065434414	1210301753	1099802247	1037290301	945310929	1084733818	782988153	1191854099	916473774	1054884952
PC 32:0	758496583	724477207	768274619	733868414	693439893	749259181	710175002	765519738	722446364	774458512
PC 33:2	267507	476121	467461	239137	220606	300963	203146	305999	248831	325328
PC 33:1	8249593	13116957	13717897	8013893	7317808	9043760	7148000	9175624	7525672	8732931
PC 33:0	8596817	12469113	13710202	8664458	7988254	9479601	8572605	9727356	9199173	8902551
PC 34:4	391388	454838	491931	399234	372784	417122	307334	483705	384327	439988
PC 34:3	1718603	2349783	2178948	1721386	1617312	2102451	1603425	2089536	1778794	2241010
PC 34:2	590874025	743461173	694194681	590880724	561090668	704126651	597275806	686538324	609059798	709461209
PC 34:1	996301774	949536297	1030604292	1009873611	971288623	1035777807	1030508945	1091385825	1025863732	1033667635
PC 34:0	299999754	276042588	308787124	299207375	286110711	320573619	311395184	327444742	310069938	311456840
PC 35:4	330597	531848	612634	321505	297921	370481	267486	398451	329017	331669
PC 35:2	876210	1249451	1339014	804725	763675	891491	762037	883618	688646	945145
PC 35:1	13221475	16935464	20662542	12144728	11285805	14589223	13755728	15404678	14066001	14135597
PC 35:0	698157	869582	1108531	671262	629549	795459	803290	850795	897966	791605
PC 36:4	295181703	269998278	305396023	299837760	282692776	319943594	280888424	331969800	322413715	327940722
PC 36:3	25010780	26283427	26593248	25447600	24617664	29287577	26963011	29759004	26076371	29014126
PC 36:1	392380436	346565074	404746111	391224144	365552741	438540185	410896069	450254454	431187414	414561617
PC 36:0	8655898	6206715	8631637	8270112	6973406	9473523	8939768	11150281	8895905	9232732
PC 36:4;O	40368	58620	36633	72606	38157	44589	37621	41486	47288	40763
PC 37:4	1780476	2620036	3107054	1845116	1797485	1965720	1819854	2164170	1983927	2079367
PC 37:2	398017	490476	738803	382964	357862	430247	495293	456341	368055	518573
PC 37:1	1445825	1288799	2052680	1245929	1038709	1538860	1673901	1831847	1516164	1537858
PC 38:6	246137495	229202473	259319402	243717461	218529358	270492168	244713669	273601597	271817280	267649261
PC 38:4	313722605	299075591	313241109	318394802	306543518	332041811	314041987	352888718	351690650	309683902
PC 38:2	17252951	13126444	17882321	15979182	13927278	18459841	17946574	22546283	16085964	20406365
PC 38:1	19760100	11930473	19120916	16972514	14036892	19616762	21101192	24295554	17318864	20474577
PC 39:6	697988	1081986	1409789	716922	698219	837809	892723	867167	837780	783029
PC 40:10	306830	310502	323085	290692	270195	315690	224205	387305	302325	307155
PC 40:7	332811021	340251402	379484582	357094114	309101915	390880660	336114493	424231678	367765640	384426259
PC 40:6	114563458	103784256	116679110	115760607	103888042	127691942	126423549	131241855	136130885	116598761
PC 40:5	13007715	14012718	13905355	12897526	12605973	14383380	13478848	16186381	14526758	14528166
PC 40:4	14946420	15061184	16122443	15502300	14187812	17292855	16500379	17336764	17975799	15316761
PC 40:2	4778288	2734313	4603885	4042619	3261401	4374850	4692514	6069394	3432229	5100825
PC 40:1	8090430	4559452	7863721	7001792	5647302	7283187	7326345	10063021	6026648	8234681
PC 40:0	644014	285018	621870	520132	411539	539594	552411	744802	447824	653564
PC 42:6	760802	760257	740050	738489	712803	817510	679793	870682	794770	806127
PC 42:5	7814437	6406432	7753901	7381534	6852938	7559150	6696165	9446758	6746639	8150234
PC 42:4	2351494	2085696	2347680	2342512	2107677	2491205	2101650	2881196	2305324	2387324
PC 42:2	2881410	1714028	2933567	2518374	2041053	2641421	2791992	3671995	2294199	2984714
PC 42:1	6954391	4136695	7250061	6202325	4660608	6054223	6434094	8439503	5388317	7288053
PC 44:4	648426	359032	661192	581421	452542	563404	562032	812142	487678	679910
PC O-24:0	5335	3389	5583	4372	4593	3817	4505	6635	3057	6433
PC O-28:0	15199	14965	22058	16185	13908	12636	14090	16597	15213	15121
PC O-29:0	20407	20594	19093	19068	18986	18613	13600	24230	14634	19932
PC P-30:0	20044	7618	28198	12496	28418	10807	8265	28935	9382	50052
PC O-30:0	509154	492157	610672	487350	420886	453158	280863	558140	303003	531098
PC O-32:1	846234	844814	945571	746489	725569	729038	499448	993664	458571	797990
PC P-32:0	4915064	4531762	4928703	4999543	4497577	5431523	5471604	5245702	5959734	4828724
PC O-32:0	12071403	11519720	12303632	12435683	11237695	12608523	11500055	13206892	12206638	11769514
PC P-34:1 or PC O-34:2_A	74115	112354	92486	50325	86827	66937	8680	75898	35104	18523
PC P-34:1 or PC O-34:2_B	2385520	1993731	2911516	2220478	2052259	2405635	2768871	2938620	2510319	2577445
PC O-34:1	30439470	29423506	32595944	30042646	27351671	31134669	27221593	34428300	26233047	31243646
PC P-34:0 or PC O-34:1	15175410	12226598	15604788	15607986	12439610	16949854	17804099	18234938	19471641	16088257
PC O-34:0	7961261	6686430	8793250	8420882	6793605	8570964	7889204	9614381	8319020	8291663
PC P-36:2	370137	370751	500307	347502	333012	352159	466113	429576	437326	393481
PC O-36:2	899117	724673	1152038	880774	740559	817704	705082	1206221	521099	933888
PC P-36:1	1261424	1085067	1557303	1187384	981866	1359428	1501859	1611114	1363848	1272569
PC O-36:1	2935402	1761264	3190677	2712280	2203449	3090792	2856904	4006644	2253481	2977213
PC O-36:0	554887	487899	582383	558726	455905	605465	538500	712842	513572	585334
PC P-38:6	6133241	5486166	6226039	6371762	6306408	7243674	7462230	8041116	8105953	7398603
PC O-37:0	4652	7202	9962	5346	6373	9841	12005	10072	13481	6490
PC O-38:6	932218	978705	1142998	1152550	949083	1103426	1075280	1401507	1102656	1147076
PC O-38:5	503595	621892	572902	532395	472331	427271	395729	585124	374406	406914
PC O-38:4	398820	433764	410385	423898	388824	422720	501244	543798	411498	389665
PC P-38:3	6128735	5938830	6855735	6146594	5049009	5886560	5860682	7531219	6531067	7687537
PC O-38:3	19623	35636	28014	34217	21793	24794	16092	46402	18875	24898
PC P-38:2	117312	78009	142098	93904	76248	115232	138808	157671	104293	103106
PC O-38:2	2872611	1349410	3065130	2909743	1946129	2554052	2077397	3614144	1651783	2793058
PC P-38:1	186595	115158	212951	161816	113782	173258	232335	235957	168093	179333
PC O-38:1	488991	267666	502623	449067	314025	465330	453092	644419	325460	444874
PC P-38:0	12899	6025	14781	11006	8374	9554	13545	14001	7861	17081
PC O-38:0	135716	108718	150480	138096	111077	147345	129131	187249	119432	148564
PC P-40:6 or PC O-40:7_A	3461059	3885519	4251397	4085675	2934528	3697165	3216950	4921353	3496775	3256823
PC P-40:6 or PC O-40:7_B	747587	702686	818541	710214	648632	763780	828481	1001240	901740	790001
PC P-40:5 or PC O-40:6	5651428	5446363	6611412	5914542	5192892	6099047	6134041	8244433	6434790	6161009
PC P-40:2	20143	15111	32613	16928	15048	20799	31820	34411	22031	25743
PC P-40:1	48308	28397	53864	36779	28768	40911	53977	56667	36100	44779
PC P-40:0 or PC O-40:1	138481	76182	143195	120460	92014	133349	129922	176336	97514	142629
PC O-40:0	36883	22835	36072	33354	26418	34726	28157	45100	28863	41915
PC P-42:1 or PC O-42:2	35368	16926	38204	28492	21152	29142	32067	45019	21798	34394
PC O-42:1	5334	2289	5295	4349	2892	4480	4811	5812	3309	5328
PE 32:0	153358	113935	57343	55445	113215	131829	121264	76023	95965	183157
PE 32:1	266405	282665	277560	250260	241416	277627	223441	301322	256450	283749
PE 34:3	6264	9302	8966	6623	6425	8122	4044	6556	5666	6054
PE 34:2	983498	1122765	1104640	941617	907254	1118540	970087	1113734	944046	1084116
PE 34:1	5862066	5778080	5925149	5635376	5627340	6010316	6077496	6416005	5811771	6430023
PE 36:4	12591280	12318034	13041838	12404611	11331969	13019567	11243092	13150427	12660355	13159784
PE 36:2	8371133	7738337	8471279	8120499	7461512	8481491	8324115	9341614	8191099	8717435
PE 36:1	8089407	7288018	8132560	7891891	7558096	8974052	8646890	8748402	8434728	8822019
PE 38:6	53698854	52585204	55151467	52564921	48577857	58576061	49246787	58077907	55962384	57770920
PE 38:5	7935081	7949532	8651058	7497054	7422426	7556243	7554399	8615010	7842612	7959700
PE 38:4	82215396	81396661	80402134	80708705	78985559	82828754	75147784	86515125	85187466	77497115
PE 38:3	16131736	12609806	14935857	16332478	15191273	16289429	14439139	16899871	14304847	16029290
PE 38:2	1318365	1000449	1244717	1172549	1014401	1338939	1328100	1519969	1063227	1448833
PE 40:6	99152707	92420975	102385563	99534714	91960475	107159037	101551670	109199068	111600667	100540213
PE 40:5	2237938	2980326	2574717	2214241	2149527	2169922	2061521	2312829	2325222	2227492
PE P-32:0	367384	309194	348609	335079	312986	337324	307511	392340	336381	383820
PE P-34:2	145064	122313	177236	125845	187837	161040	177782	250208	112366	245165
PE P-34:1	11193192	8012849	10726926	9903687	9182543	10502551	10925181	12352720	8855178	10994549
PE P-35:1	190565	193380	312196	174131	139192	173765	232099	209677	181572	205605
PE P-36:5	859628	833991	1136106	1058269	1080008	1283070	858947	1152314	997914	1060569
PE P-36:4 or PE O-36:5	9471443	8950172	9726564	9396398	9673181	9706696	9047122	10701383	9734288	9653628
PE O-36:4	1342048	863620	1205882	1196156	1213633	1304850	1255136	1538621	1120438	1332759
PE P-36:2 or PE O-36:3	7616966	5473335	8256770	6925445	6334946	7741033	8750427	9433015	7179029	8660287
PE P-36:1 or PE O-36:2	10920861	7454803	11111856	10186471	8870890	11532293	12135879	13464753	10623584	11075776
PE P-37:4 or PE O-37:5	199726	226444	277674	169817	183313	218504	216961	230482	251723	214194
PE P-37:1 or PE O-37:2	159664	125383	225533	132556	102892	146997	176529	178209	131655	152069
PE O-38:7	296757	285513	345011	317847	290847	310778	322203	372158	365799	371781
PE P-38:6	33748795	30568220	34586345	35529253	32059000	35556896	31243146	38288535	33989474	35916250
PE P-38:5	8153636	7906822	8204970	7857962	7709319	8411677	8783152	9424985	9370112	8277636
PE P-38:4	11246887	10365014	10885197	11089532	11006618	11268728	11503490	11948543	11156724	11510963
PE P-38:3	2032288	1560137	1913376	1986803	1760182	2058487	1923687	2498306	1933135	1824738
PE P-38:2	3719790	2215171	3738056	3195752	2770166	3640497	4286656	4582152	3229116	3609636
PE P-38:1	4787791	2853443	4652288	4245343	3431642	4552306	4948277	5557586	3875723	4392375
PE P-40:7	13177708	12286154	13676619	13253588	12897285	14087437	14170955	15857383	15717393	14169777
PE O-40:8	106628065	99491812	110341443	107666276	106107091	115993704	116807559	129426100	129369441	114784528
PE P-40:6 or PE O-40:7	59087554	54294537	61642511	58756667	55148847	61094688	58121333	65226268	64350247	60735047
PE P-40:4	14586977	14775785	14744960	14901730	14292819	15590479	15101012	16362381	17168295	14256254
PE P-40:2	1219083	759933	1243331	999811	848484	1182737	1220095	1526549	930603	1218357
PE P-40:1	970699	570299	943356	826931	666351	921759	907841	1125939	690447	1005464
PE P-42:6 or PE O-42:7	762802	734421	690630	740700	681412	672059	549014	725561	662379	603662
PE P-42:5 or PE O-42:6	1079268	1089520	1041112	1051062	988670	1044026	881440	1150666	1019222	929601
PE P-42:4 or PE O-42:5_A	1124914	1012422	1099101	1107851	1009077	1117004	994177	1221088	1166827	992505
PE P-42:4 or PE O-42:5_B	145797	90348	151395	123150	96998	136599	138954	167206	101211	154608
PE P-44:5 or PE O-44:6	144254	120711	133299	123184	119951	143353	138878	172880	150348	151086
PI 34:1	156596424	134939681	157825061	162084848	158256740	169919575	156643142	163912546	162816231	177646422
PI 32:1	3617229	3478050	3474257	3625771	3636004	4603428	3260485	4163537	3939547	4044521
PI 34:0	5822392	7440955	5673741	5340530	5646600	5808877	4907286	4921569	5550011	5983326
PI 36:4	1070186	970161	1202522	1088227	1032031	1272328	1014710	1248197	1075367	1193338
PI 38:7	5976949	4900961	5997675	5979287	5137697	6245727	4709535	6733195	5643941	6417665
PI 38:6	107284	90070	112284	105169	95963	133642	102886	123545	104024	352939
PI 38:4	1418117	1669143	1602744	1582893	1680064	1767586	1497690	1717113	1557505	1990516
PI 40:8	936681	927392	1015933	868026	862028	985488	847140	1073521	916994	946881
PS 40:6	43357683	42152341	44072811	45013427	44319371	47578324	44732529	45649731	45006820	50314890
Cer 34:1;O2	605801	587191	643343	546552	581426	552627	398181	704183	445284	558645
Cer 36:1;O2	10415283	10278110	10396119	9483342	10827602	9105130	7352677	11057529	8586743	8793025
Cer 38:1;O2	1320570	1144824	1369846	1249507	1205470	1133806	1002750	1292827	1053520	1155624
Cer 38:0;O2	17712	14825	16280	15905	15524	28381	16570	20958	15867	21261
Cer 39:1;O2	59806	55531	77000	59752	59059	62383	60805	71679	63687	55330
Cer 40:2;O2	407656	284437	393679	373147	351406	403692	388595	505418	324617	447940
Cer 40:1;O2	422190	354922	408334	388936	363482	408790	320608	466515	300703	358056
Cer 40:0;O2	29337	17329	24056	31855	22581	52894	23183	32856	15040	18949
Cer 41:2;O2_A	53752	44930	72862	55179	53347	58903	71766	71414	63721	61213
Cer 41:2;O2_B	5233	4421	4929	5814	3377	6792	4943	6299	6669	3392
Cer 41:1;O2	133089	121057	152810	117136	110128	130139	107632	147536	110813	113431
Cer 42:3;O2	516571	485678	574279	480950	466316	518812	453170	611237	450746	523781
Cer 42:2;O2	2416214	1956961	2622762	2416700	2052102	2355808	2150641	3169245	1769649	2460768
Cer 42:1;O2	333194	285209	340766	339545	299141	329869	253202	396668	232742	302341
Cer 42:0;O2	30721	24566	28631	31309	24849	37280	25259	32643	20861	20788
Cer 43:2;O2	9244	8857	11734	8865	7175	10509	10951	13669	9860	7157
Cer 43:1;O2	212928	211593	250667	219281	219308	256194	234732	263683	235466	202317
HexCer 34:4;O2	15268	4145	17182	10822	10679	14958	9999	20172	7584	14840
HexCer 34:1;O2	52933	34031	50611	42750	39289	50954	48826	66141	39606	62884
HexCer 36:2;O2_A	280519	242526	272828	269419	242406	308367	308764	319706	268893	312680
HexCer 36:2;O2_B	524287	315555	414500	417981	384477	518143	551820	636187	441534	578884
HexCer 36:1;O2	2605978	1766318	2536487	2559378	2080463	2901802	2497202	3414265	2140276	3058030
HexCer 38:5;O2	547200	341248	431074	514274	453895	565706	479157	671415	465616	537649
HexCer 38:1;O2	405659	228415	328015	398874	322273	440689	394438	517476	299650	558468
HexCer 40:2;O2	3145317	1807467	2920221	2734326	2273619	3010145	3368011	3717457	2652807	3551781
HexCer 40:1;O2	3409793	1661602	3064386	3071392	2376880	3433319	3491897	4313328	2705860	3752231
HexCer 41:2;O2	647356	435782	769042	573158	509184	679089	899420	804806	722767	711753
HexCer 42:3;O2_B	2005163	1689500	2405759	1863320	1668310	2128799	2417235	2754576	2206532	2400152
HexCer 42:3;O2_C	1636855	919903	1451458	1443776	1133484	1542336	1332310	1618733	1062206	1405718
HexCer 42:2;O2_A	19271327	9840766	17913824	16402888	13964249	20105463	22910229	24951564	17625712	21797875
HexCer 42:2;O2_B	3931021	2384798	3806822	3413589	2862418	3766141	4512711	4412751	3528936	4039541
HexCer 42:1;O2	8485649	4122481	7581076	7448365	5657406	7981869	9108266	10075148	6852576	8545329
HexCer 43:3;O2	202820	119316	220903	186832	147648	214375	223278	237318	165225	201723
HexCer 43:2;O2_A	319744	196576	327368	271494	240747	329917	459487	388274	315769	300986
HexCer 43:2;O2_B	107525	75601	118223	88663	79510	110129	139645	122194	110189	97005
HexCer 43:1;O2	169662	108569	189116	158336	134507	181382	225560	231859	190728	179152
HexCer 44:5;O2	152446124	101529010	141655437	142119092	131748461	148640652	164536016	167819884	144189425	158086344
HexCer 44:4;O2	16512235	9500854	15290590	15260167	12477128	15516345	17230801	18218387	14394853	16042830
HexCer 44:3;O2	2150744	1040233	2090778	1926019	1419310	2259976	2090524	2558960	1570403	1893375
HexCer 44:2;O2	204557	92747	171427	160722	134152	193442	229055	235144	157268	195949
HexCer 44:1;O2	99398	51316	87316	84464	69709	92128	103087	111370	85538	95396
HexCer 45:5;O2	547014	319731	603845	462101	388198	530213	755013	612413	552303	540546
HexCer 46:5;O2	534230	237564	468295	445478	367516	517087	601017	623881	459318	491017
HexCer 46:4;O2	235293	96082	212822	206086	152333	230914	253491	295768	183426	218764
SM 32:1;O2	56043	55824	65479	53687	51732	58638	46779	66424	51317	56409
SM 33:1;O2	127649	272020	221987	130203	127488	176488	189752	177843	163797	137795
SM 34:2;O2	96945	94569	88563	97936	92470	122964	120445	116819	133175	122383
SM 34:1;O2	5123586	5655180	5655700	4977947	4546569	5747343	5556875	6202696	5739482	5276023
SM 34:0;O2	147798	237627	199600	161330	150907	202648	176800	191615	177888	148231
SM 35:1;O2	244277	465433	432332	259379	247709	324084	310634	289972	355524	299933
SM 36:2;O2	13755324	11906482	11361146	14110494	11873460	17047804	17005746	15009247	19989751	16061683
SM 36:1;O2	142902883	151418056	147741635	148040442	142440321	155816873	159554926	155819440	173915853	158658492
SM 36:0;O2	2434694	2813286	2532859	2614621	2494933	3051106	2825162	2867110	3071857	2518468
SM 38:2;O2	346895	200126	233857	284773	401735	483030	530707	353717	552672	384639
SM 38:1;O2	13819815	10767961	14486914	13314852	12209884	13919194	15064910	15472730	15183953	14363193
SM 39:1;O2	109258	84424	146370	99522	96813	126482	159257	147406	159585	148999
SM 40:2;O2	865174	464333	697301	605148	658038	873112	1011861	898088	660689	909442
SM 40:1;O2	4053324	3102940	3624945	3509607	3172534	4300628	3986608	4666340	3490164	3875864
SM 41:2;O2	1556112	1093440	1715543	1361015	1012234	1608101	1965604	1722490	1632983	1592668
SM 41:1;O2	451702	366166	512942	422541	366106	526061	575558	574260	499568	530207
SM 42:2;O2	66371369	44644759	63695194	56292313	44386811	70883777	77943922	80250752	61403587	68733037
SM 42:1;O2	2462348	1905127	2456188	2263897	1892295	2778003	2636973	3097481	2307423	2561053
SM 43:2;O2	21546	14137	25569	17972	13924	25542	36078	32569	29669	23435
SM 44:3;O2	20047	19273	26312	22204	13306	24607	37372	32860	30787	21043
SM 44:2;O2	616243	387369	593083	577503	432700	702964	715114	757936	663804	641334
SM 44:1;O2	11170	10464	14313	10523	9178	13084	10795	15815	15751	14067
CE 14:0	19883	19342	18958	20213	20182	26063	18432	20166	20793	5387
CE 16:1	173241	177467	168244	169710	173176	173044	167824	169133	163481	139378
CE 16:0	94114	102151	102772	101275	108536	131661	109825	112186	112541	63626
CE 18:2	48274	63352	51224	63728	70281	122699	67808	57682	62831	40952
CE 18:1	176972	181874	187266	180127	186412	211070	196905	194112	188180	141860
CE 18:0	26519	24716	27034	29886	30699	32490	30447	28266	29228	19746
CE 19:2	11057	16698	12512	18418	20128	36886	16865	13800	15922	10423
CE 20:5	1368	2096	1345	913	1523	6926	1718	1591	1525	1681
CE 20:4	227106	198672	200742	319306	235004	279967	236444	223496	268065	258019
CE 20:3	6974	8161	6331	7810	7312	11960	9913	8271	9793	7312
CE 22:6	69754	64248	74205	69412	70570	131858	84456	87318	91979	78931
CE 22:4	4491	2787	3046	3719	4701	9060	5825	4532	5510	4247
MG 14:0	2478143	3844802	3484471	2749086	3032392	2733665	2588117	1900923	2670514	2410414
MG 15:0	318433	436678	415213	341859	383183	341264	322688	270875	347283	288272
MG 16:1	31373	32136	31569	31138	33719	33370	32875	37200	34880	37916
MG 16:0	40740247	48824437	44852186	42360588	43681641	41163971	40384903	37800078	42350185	40618072
MG 17:0	834228	1065070	1005898	868799	900449	856115	796895	744060	866064	769165
MG 18:2_A	2345	2045	2387	2788	3022	3357	4048	4209	4845	2606
MG 18:1	506451	735288	708183	553490	644480	573417	561213	442965	595203	533404
MG 18:0	35889482	41673676	40432920	37934380	38522068	37940617	36066840	34919859	37551468	35426019
MG 19:0	57420	75879	68535	58811	61516	59027	54900	50849	57595	59304
MG 20:4	77014	57172	84988	53826	87821	98251	138175	159933	199977	135273
MG 20:0	1303714	1650241	1780964	1459107	1631465	1482368	1374129	1213145	1547432	1353736
MG 22:1	90334	89065	89658	88837	88564	89771	89429	94445	91881	110835
MG 22:0	227983	347509	327515	246562	265137	250143	229230	180385	251405	231756
MG 24:0	90018	89396	92197	89354	90229	89249	89882	88264	87088	252080
DG 32:0	87953	135549	81835	79211	109743	81349	90940	66332	82928	64196
DG 34:2	7662	13011	4757	1756	7978	6951	6828	5713	7689	2838
DG 34:1	885750	931179	733568	657908	832910	784931	923291	781229	831087	707032
DG 34:0	905393	1661273	1156214	1007694	1067390	1139057	928979	884397	1176383	1002316
DG 35:1	41216	37624	61973	35779	32409	38017	52767	39731	42063	25571
DG 36:4	238493	168313	203996	95591	225193	217943	346098	246421	300393	225973
DG 36:3	55179	33566	43389	25634	46606	72851	81156	52475	54585	54028
DG 36:2	391285	325449	333617	308820	332119	364536	418392	351447	348154	341942
DG 36:1	1272165	915180	1159116	1016574	1035247	1334795	1899188	1411719	1503766	1299292
DG 36:0	697449	1065512	1077906	705102	765764	913831	715382	738926	901776	918528
DG 38:6	337730	311038	304347	191567	257824	259063	341948	278575	287346	288618
DG 38:4	8185985	7897100	7080736	4996046	7262214	7245551	8949880	7782695	8850143	7639354
DG 38:3	217022	137703	167973	147754	172931	204422	281544	211136	231630	236417
DG 38:2	175187	90977	138714	111547	117425	188925	271603	208091	187619	189316
DG 38:1	370136	186590	330422	315500	263609	409877	571782	510864	388708	378177
DG 40:5	129958	68593	90442	35215	60600	104119	162073	127895	113161	121266
TG 40:0	363898	350680	356806	361105	361452	350085	347766	361648	349340	399416
TG 42:1	124427	118194	115763	122408	119099	125782	115268	122243	116831	103107
TG 42:0	173380	176265	182092	179378	176898	182252	175496	172713	166826	128238
TG 43:1	32230	32209	29875	30952	32128	31537	27110	29360	25714	32560
TG 43:0	80160	81029	80431	79765	78617	77103	80011	75808	76439	107176
TG 44:2	24663	24489	23446	25555	25418	26419	25451	25115	25298	24089
TG 44:1	176874	172494	167859	177102	173487	176085	161871	167428	157702	158019
TG 44:0	333570	315745	307938	325161	322811	322370	309027	312007	309730	343011
TG 45:2	30895	30425	30933	32367	32696	27941	28711	30280	28827	29083
TG 45:1	215600	201674	196974	203246	206484	201769	201930	205672	196514	211931
TG 45:0	311114	298681	299299	299827	313275	296982	300931	295888	295435	322519
TG 46:2	223350	204483	204099	230003	214985	233717	198731	211376	194110	171850
TG 46:1	454788	429919	435138	462766	466888	467903	434525	438861	430598	414867
TG 46:0	621823	583478	585260	596858	597876	616878	576728	582129	594538	639285
TG 47:2	194381	192443	189868	187691	189702	191841	189464	189820	185883	181051
TG 47:1	431931	416345	427812	430467	429341	419948	416919	420705	419620	443777
TG 47:0	493590	484885	470282	455694	478304	466956	459283	449649	445088	571781
TG 48:3	95621	95448	93636	94818	90668	97149	88379	90712	92736	90721
TG 48:2	444229	423108	424683	477205	436333	484495	408743	425412	407206	321759
TG 48:1	723266	697741	692063	697559	719242	738104	676103	697267	662828	626043
TG 48:0	1322055	1260184	1198915	1226398	1242844	1458520	1279802	1290324	1336950	1392104
TG 49:3	56919	53588	53540	54311	53405	53679	48432	50604	47731	52923
TG 49:2	231326	218605	220831	219394	222838	219958	219108	219349	211602	251274
TG 49:1	385821	385577	378474	380877	385925	378914	364017	368514	354830	368567
TG 49:0	274574	276128	277587	261074	265772	262172	259149	245660	245195	326411
TG 50:4	12592	12979	5312	24410	12659	30144	7999	12065	10146	953
TG 50:3	210011	217656	195675	262234	218966	293023	213210	222595	218313	132259
TG 50:2	627548	674360	583430	662557	609738	749418	589906	609864	588161	454835
TG 50:1	1566380	1534477	1480747	1432351	1408828	1609803	1539908	1577201	1613531	1422892
TG 50:0	1080785	1065159	1007456	1019262	985727	1176972	1124245	1078298	1178915	1113291
TG 51:3	37575	33966	31806	33325	32465	31604	31408	28716	31302	37823
TG 51:2	145941	144193	145688	140411	143751	139390	138650	140077	135457	136716
TG 51:1	144292	148579	151435	140747	142028	146733	136233	137366	135993	142685
TG 51:0	77813	81691	84613	81688	82023	80972	80148	78645	80708	89074
TG 52:6	37209	36293	41415	29446	30314	44308	26511	38661	31908	27876
TG 52:5	16983	16268	17325	19810	17456	27563	16696	16403	19356	15142
TG 52:4	236648	232121	214479	202400	187198	238902	220399	223205	240338	197036
TG 52:3	432420	480495	404044	505609	425052	650800	471665	484480	435635	334507
TG 52:2	1004667	1003800	965901	930834	901266	1066320	973308	1009138	957633	814899
TG 52:1	1019701	954325	924968	855306	872449	1001069	1012364	1013219	1095425	899385
TG 52:0	460651	416399	407311	416351	423129	489502	492917	455481	510972	464061
TG 53:4	85364	91587	76776	81448	76426	99794	88626	88307	93159	80320
TG 53:2	24029	22964	21395	19164	22566	21371	23273	22088	21124	44585
TG 53:1	24379	23640	24944	22232	24727	25714	23427	22413	23553	30111
TG 54:7	552834	545636	551285	417936	415387	639424	422442	609670	500421	452698
TG 54:6	1088056	1012888	1058810	914313	891216	1200377	951901	1168777	1077643	973105
TG 54:5	264225	271216	245440	233776	218430	254384	258714	280543	269178	233952
TG 54:4	668574	695430	633846	651513	603615	753075	695545	699586	722288	593985
TG 54:3	739455	736321	694743	742966	716523	828140	745419	790506	756203	574025
TG 54:2	311566	287297	294697	278436	289774	312601	312563	325741	303663	234387
TG 54:1	182008	169214	169651	161798	163466	175826	188727	183013	180337	141857
TG 54:0	121968	114418	118628	115017	118345	123280	118853	115503	111255	108081
TG 55:7	49817	46944	44593	36117	38302	51337	38488	43495	42241	32082
TG 55:6	416518	386637	397240	335278	322798	447317	353319	425827	402788	368075
TG 55:5	91045	93374	87293	84791	80922	93300	91414	98131	102213	88472
TG 55:4	143482	147589	133458	125806	122374	144049	149195	151817	161486	136698
TG 55:3	244873	235425	228799	242312	238899	265657	242501	251832	242334	190236
TG 56:8	117338	132145	130289	111323	89630	151624	127013	140286	129441	119404
TG 56:7	907100	850142	878529	678082	695684	868047	783871	968661	884673	819362
TG 56:6	765222	716283	740280	617783	608098	747639	739668	830814	796523	743435
TG 56:5	251109	267377	233668	210056	206387	235593	271984	272038	294398	231681
TG 56:4	947109	991170	885862	788686	807458	897879	1020601	978334	1088555	926428
TG 56:3	30290	27249	26532	30282	27353	29535	27774	30857	28585	23799
TG 56:2	24486	18925	19254	18484	18182	21278	19823	24630	16931	21505
TG 56:1	580495	484253	548711	541446	539205	434903	538208	560565	561846	432696
TG 57:8	28770	35293	33922	23557	21581	39364	27443	34145	31386	28060
TG 58:10	219675	193827	226649	190366	171017	213854	186663	246015	220785	205049
TG 58:9	68565	69851	71197	59663	55818	87189	68678	89316	78556	69688
TG 58:8	122088	111938	114985	126425	100502	124481	137738	143775	138391	119481
TG 58:7	109180	104928	117786	77512	88997	118264	137006	138997	142065	121951
TG 58:6_A	14018	16273	13568	9398	8319	19683	31808	24511	21647	10046
TG 58:6_B	49780	40484	47331	29543	36291	39161	69645	59204	57845	49204
TG 58:5	8741	7176	8656	6088	5608	7439	13836	11800	9885	11422
TG 58:1	73899	65546	74319	71721	74865	72110	74541	79577	67655	141741
TG 60:12	382158	327055	432071	306368	315248	399705	381627	507203	433553	388420
TG 60:11	73117	66983	74707	55179	50674	58455	62904	84914	78456	69683
TG 62:13	22193	19373	28079	17522	20567	27878	23286	40060	34025	30105
TG 62:12	50269	41647	62815	37680	46937	55046	80429	92146	88860	85525
Piperine	93733	104874	105239	112033	115709	127315	108876	108934	120772	119409
Linoleoyl-EA	3893	2918	4397	4529	3307	3929	4301	4651	4242	3901
Palmitoyl-EA	88344	82816	84641	88006	84060	91429	92406	94852	89988	91134
Oleoyl-EA	17987	13174	15945	17664	12874	18419	16399	23111	16601	17511
Coenzyme Q9	795737	783521	815736	784459	704149	849864	769429	896330	872944	945893
Coenzyme Q10	741925	659138	789603	764969	657600	808445	691950	899156	824749	857879
alpha-Tocopherol	456789	465926	589698	538791	441777	548792	534645	629839	654295	850932
Sphingosine	134779	112223	139342	135200	121269	135167	140729	154712	146817	147395
14-Demethyllanosterol	58223	70079	75523	48662	51681	66229	49728	102968	59115	72034
7-Dehydro-desmosterol	744510	787664	788140	784936	703640	784502	28811	857947	703986	820902
Cholestenone	55773	66281	58976	76579	53195	59897	57019	65055	62066	64268
Cholesterol	8582964	7668844	9374348	8079167	8030616	9718504	8773877	10319565	9640224	9232125
Lanosterol	14365	16040	16615	14665	14974	19043	13751	17907	15901	23235
5-cholesten-3-one	36416	34851	35784	40706	31326	40133	37863	40868	33028	36002
MG 14:1	12338	10988	12893	14359	11351	15372	14081	15339	14390	15501
MG 18:2_B	8478	14625	10415	9888	11564	9588	11256	8565	12495	6793
DG 38:5	53691	48861	27137		29023	20054	48092	24056	6030	31785
TG 46:3	32883	28365	26954	28385	30598	33404	29586	28610	27789	
TG 58:2	14871	10959	9625	11350	12421	12096	12722	12036	10109	
PE P-32:1			6454		4104		17495	34330		20906
CE 22:5						35250				
MS_METABOLITE_DATA_END
#METABOLITES
METABOLITES_START
metabolite_name	Study_Compound_ID	MZ	RT	HMDB_ID
PC 12:0/12:0 [iSTD]	TF01	622.44423340000003	6.6	Internal standard
LPC 0:0/14:0	QI01301	468.30879490000001	4.3290166670000003	NA
LPC 14:0/0:0	QI01421	468.30871009999998	4.431533333	HMDB0010379
LPC 16:1/0:0	QI01573	494.32433889999999	4.5875333329999997	HMDB0010383
LPC 16:0/0:0	QI01904	496.34011229999999	4.9440999999999997	HMDB0010382
LPC 17:0/0:0	QI02161	510.35586699999999	5.2293666669999999	HMDB0012108
LPC 0:0/18:2	QI01667	520.34030789999997	4.6632999999999996	HMDB0061700
LPC 18:2/0:0	QI01756	520.34025799999995	4.7747333330000004	HMDB0010386
LPC 0:0/18:1	QI01945	522.35590609999997	4.9975833329999997	HMDB0061701
LPC 18:1/0:0	QI02070	522.35602449999999	5.1179333329999999	HMDB0002815
LPC 0:0/18:0	QI02299	524.37136699999996	5.3808999999999996	HMDB0011128
LPC 18:0/0:0	QI02467	524.37156990000005	5.5279833329999999	HMDB0010384
LPC 19:0/0:0	QI02713	538.3876295	5.8444333329999996	NA
LPC 0:0/20:4	QI01686	544.34020610000005	4.6944999999999997	HMDB0061699
LPC 0:0/20:3	QI01849	546.35570849999999	4.8638833330000004	NA
LPC 20:3/0:0	QI01941	546.35684300000003	4.988683333	HMDB0010393
LPC 0:0/20:2	QI02108	548.37126360000002	5.1714166669999999	NA
LPC 20:2/0:0	QI02233	548.37093689999995	5.2873000000000001	HMDB0010392
LPC 0:0/20:1	QI02476	550.38693809999995	5.5369000000000002	NA
LPC 20:1/0:0	QI02565	550.38733649999995	5.6795333330000002	HMDB0010391
LPC 20:0/0:0	QI02947	552.40328290000002	6.1787166669999998	HMDB0010390
LPC 0:0/22:6	QI01673	568.34006239999997	4.681133333	NA
LPC 0:0/22:4	QI02072	572.37144909999995	5.1179333329999999	NA
LPC 22:4/0:0	QI02163	572.37126890000002	5.2293666669999999	HMDB0010401
LPC 22:1/0:0	QI02999	578.41893879999998	6.2857000000000003	HMDB0010399
LPC 22:0/0:0	QI03390	580.43453050000005	6.8562000000000003	HMDB0010398
LPC 23:0/0:0	QI03547	594.45036370000003	7.1860333330000001	NA
LPC 24:1/0:0	QI03424	606.44982219999997	6.9542666669999997	HMDB0010406
LPC 24:0/0:0	QI03776	608.46535540000002	7.4935666669999996	HMDB0010405
LPC 26:1/0:0	QI03974	634.48006810000004	7.587166667	HMDB0029220
LPC 26:0/0:0	QI04371	636.4973741	8.1131166669999999	HMDB0029205
LPC P-16:0/0:0	QI02151	480.34550330000002	5.2248999999999999	HMDB0010407
LPC O-16:0/0:0	QI02223	482.36046270000003	5.2873000000000001	HMDB0243890
LPC O-18:1/0:0	QI02373	508.37610590000003	5.4522166670000001	NA
LPC O-18:0/0:0	QI02785	510.39252190000002	5.9157500000000001	HMDB0011149
LPE 0:0/16:0	QI01827	454.29281179999998	4.8371333329999997	HMDB0011473
LPE 16:0/0:0	QI01919	454.2930672	4.9574833329999999	HMDB0011503
LPE 0:0/18:1	QI01971	480.30891389999999	5.0154166670000002	HMDB0011475
LPE 18:1/0:0	QI02092	480.30894489999997	5.1357666670000004	HMDB0011506
LPE 18:0/0:0	QI02484	482.3245589	5.5458166670000004	HMDB0011130
LPE 0:0/20:4	QI01702	502.29309009999997	4.7123333330000001	HMDB0011487
LPE 22:6/0:0	QI01685	526.2931959	4.6944999999999997	HMDB0011526
PC 28:0	QI04126	678.50726469999995	7.78775	HMDB0007866
PC 29:0	QI04328	692.52297439999995	8.0551666669999999	HMDB0007932
PC 30:1	QI04220	704.5229587	7.9571166670000002	HMDB0007870
PC 30:0	QI04496	706.538274	8.3136833330000002	HMDB0007869
PC 31:1	QI04439	718.53821330000005	8.2200833329999998	HMDB0007936
PC 31:0	QI04746	720.55407449999996	8.5454500000000007	HMDB0007935
PC 32:2	QI04378	730.53853819999995	8.1264833329999995	HMDB0007874
PC 32:1	TF02	732.55378340000004	8.4784864859999995	HMDB0007873
PC 32:0	QI04924	734.56945440000004	8.7861333330000004	HMDB0007871
PC 33:2	QI04587	744.55291309999996	8.3760833330000004	HMDB0007940
PC 33:1	QI04859	746.56888739999999	8.7058999999999997	HMDB0007938
PC 33:0	QI05035	748.5852701	9.0178999999999991	HMDB0007937
PC 34:4	QI04395	754.53878589999999	8.1532166670000006	HMDB0007883
PC 34:3	QI04629	756.55343640000001	8.4161999999999999	HMDB0008006
PC 34:2	TF03	758.56943339999998	8.6306962029999994	HMDB0007973
PC 34:1	QI04990	760.58509040000001	8.9287666669999997	HMDB0007972
PC 34:0	QI05177	762.60091560000001	9.2318499999999997	HMDB0007970
PC 35:4	QI04615	768.55409729999997	8.4028166669999997	HMDB0008428
PC 35:2	QI04955	772.58461260000001	8.8485333330000007	HMDB0007946
PC 35:1	QI05102	774.60055060000002	9.1560833329999998	HMDB0256160
PC 35:0	QI05324	776.6156277	9.4413333329999993	HMDB0007944
PC 36:4	QI04821	782.56921209999996	8.6479666670000004	HMDB0007983
PC 36:3	QI04909	784.58347289999995	8.7593833330000006	HMDB0008105
PC 36:1	QI05270	788.61652790000005	9.3655666669999995	HMDB0008038
PC 36:0	QI05523	790.63220100000001	9.6463666670000006	HMDB0008036
PC 36:4;O	QI03745	798.5655921	7.4757499999999997	NA
PC 37:4	QI04974	796.58411260000003	8.8797333330000008	HMDB0007955
PC 37:2	QI05218	800.6141867	9.2764166669999994	HMDB0256163
PC 37:1	QI05429	802.63280989999998	9.5482999999999993	HMDB0007952
PC 38:6	QI04777	806.56901089999997	8.5810999999999993	HMDB0007991
PC 38:4	QI05073	810.60016610000002	9.1070499999999992	HMDB0008048
PC 38:2	QI05337	814.63212659999999	9.4547000000000008	HMDB0008270
PC 38:1	QI05594	816.64836449999996	9.7265833330000007	HMDB0008269
PC 39:6	QI04940	820.58345080000004	8.8262499999999999	HMDB0240629
PC 40:10	QI04493	826.535617	8.2958499999999997	HMDB0008511
PC 40:7	TF04	832.58508340000003	8.7413924049999991	HMDB0008123
PC 40:6	QI05044	834.6004709	9.0446500000000007	HMDB0008057
PC 40:5	QI05146	836.61548689999995	9.1917333330000002	HMDB0008312
PC 40:4	QI05290	838.63194109999995	9.4056666670000002	HMDB0008342
PC 40:2	QI05731	842.66370170000005	9.8513833329999994	HMDB0008053
PC 40:1	QI06050	844.68010479999998	10.17675	HMDB0007993
PC 40:0	QI06298	846.69590189999997	10.453099999999999	HMDB0007992
PC 42:6	QI05246	862.63191340000003	9.3076166669999996	HMDB0008702
PC 42:5	TF05	864.64768340000001	9.4659493670000003	HMDB0008318
PC 42:4	QI05572	866.66294530000005	9.7042999999999999	HMDB0008798
PC 42:2	QI06096	870.69587939999997	10.230233330000001	HMDB0008125
PC 42:1	QI06401	872.71064430000001	10.57343333	HMDB0008059
PC 44:4	QI06189	894.69315300000005	10.332750000000001	HMDB0008421
PC O-24:0	QI03612	608.46653300000003	7.3286666670000002	NA
PC O-28:0	QI04387	664.52866449999999	8.1398499999999991	NA
PC O-29:0	QI04597	678.5425176	8.3894500000000001	NA
PC P-30:0	QI04817	690.54346729999997	8.6434999999999995	HMDB0011203
PC O-30:0	QI04818	692.55823150000003	8.6434999999999995	HMDB0013341
PC O-32:1	QI04904	718.57371469999998	8.7638499999999997	HMDB0013404
PC P-32:0	QI05066	718.57432630000005	9.0892166670000005	HMDB0007896
PC O-32:0	QI05068	720.59013830000004	9.0981333329999998	NA
PC P-34:1 or PC O-34:2_A	QI04979	744.58895500000006	8.8975666669999995	HMDB0011151
PC P-34:1 or PC O-34:2_B	QI05161	744.59006620000002	9.2140166669999992	HMDB0011210
PC O-34:1	QI05162	746.60637680000002	9.2050999999999998	HMDB0013426
PC P-34:0 or PC O-34:1	TF08	746.60581839999998	9.5162658229999995	HMDB0011208
PC O-34:0	QI05399	748.62165100000004	9.5304666670000007	HMDB0013405
PC P-36:2	QI05258	770.60445460000005	9.3477333330000008	HMDB0011244
PC O-36:2	QI05254	772.62151630000005	9.3388166669999997	HMDB0013418
PC P-36:1	QI05505	772.62169040000003	9.6329833330000003	HMDB0011243
PC O-36:1	QI05520	774.63726959999997	9.6463666670000006	HMDB0013427
PC O-36:0	QI05818	776.65296839999996	9.9316166670000001	HMDB0013417
PC P-38:6	TF10	790.57451839999999	8.8722151900000004	HMDB0011229
PC O-37:0	QI06022	790.67050119999999	10.14555	NA
PC O-38:6	QI04973	792.58940340000004	8.8797333330000008	HMDB0013409
PC O-38:5	QI05065	794.60637919999999	9.0802999999999994	HMDB0013432
PC O-38:4	QI05217	796.62060919999999	9.2764166669999994	HMDB0013420
PC P-38:3	TF09	796.62146840000003	9.3955063289999998	HMDB0011252
PC O-38:3	QI05401	798.6346532	9.5260166670000004	HMDB0013440
PC P-38:2	QI05567	798.63909660000002	9.6998499999999996	HMDB0011250
PC O-38:2	TF06	800.65276840000001	9.7577848100000004	HMDB0013431
PC P-38:1	QI05884	800.65400020000004	9.9940166670000004	HMDB0011249
PC O-38:1	QI05909	802.66759379999996	10.011850000000001	HMDB0013416
PC P-38:0	QI06142	802.66747720000001	10.28373333	HMDB0011223
PC O-38:0	QI06187	804.68489279999994	10.332750000000001	HMDB0013408
PC P-40:6 or PC O-40:7_A	TF07	818.60581839999998	9.0131012659999996	HMDB0011294
PC P-40:6 or PC O-40:7_B	QI05241	818.60596550000002	9.2987000000000002	HMDB0011294
PC P-40:5 or PC O-40:6	TF11	820.62146840000003	9.1841772150000001	HMDB0013422
PC P-40:2	QI05977	826.67124479999995	10.087616669999999	HMDB0011323
PC P-40:1	QI06225	828.6863912	10.36841667	HMDB0011231
PC P-40:0 or PC O-40:1	QI06238	830.69987449999996	10.377333330000001	HMDB0011230
PC O-40:0	QI06525	832.71571600000004	10.72051667	HMDB0013421
PC P-42:1 or PC O-42:2	QI06313	856.71699750000005	10.470916669999999	HMDB0013438
PC O-42:1	QI06573	858.73232089999999	10.800750000000001	HMDB0013434
PE 32:0	QI04927	692.52277779999997	8.8039666669999992	HMDB0008923
PE 32:1	QI04671	690.50727940000002	8.4786000000000001	HMDB0008924
PE 34:3	QI04480	714.50558030000002	8.2869333330000003	HMDB0008836
PE 34:2	QI04807	716.52218419999997	8.6256833329999996	HMDB0008928
PE 34:1	QI04996	718.53799319999996	8.9465833329999995	HMDB0008927
PE 36:4	QI04827	740.52221440000005	8.6568833329999997	HMDB0008937
PE 36:2	QI05055	744.55393600000002	9.071383333	HMDB0008994
PE 36:1	QI05269	746.56989529999998	9.3655666669999995	HMDB0008993
PE 38:6	QI04783	764.52227000000005	8.5855666670000002	HMDB0009102
PE 38:5	QI04925	766.53682849999996	8.7861333330000004	HMDB0009069
PE 38:4	QI05075	768.55409420000001	9.1159666670000004	HMDB0009003
PE 38:3	TF12	770.56943339999998	9.2445569620000008	HMDB0009354
PE 38:2	QI05323	772.58568539999999	9.4413333329999993	HMDB0008942
PE 40:6	QI05048	792.55358220000005	9.0490999999999993	HMDB0009012
PE 40:5	QI05225	794.56976810000003	9.2853333330000005	HMDB0009651
PE P-32:0	QI05071	676.52819009999996	9.1070499999999992	HMDB0011158
PE P-34:2	QI04994	700.52874569999994	8.9376833330000007	HMDB0011343
PE P-34:1	QI05172	702.54337190000001	9.2229333330000003	HMDB0008952
PE P-35:1	QI05322	716.55889260000004	9.4368666670000003	NA
PE P-36:5	TF14	722.51191840000001	8.6810126580000002	HMDB0011445
PE P-36:4 or PE O-36:5	QI04997	724.52755230000002	8.9465833329999995	HMDB0011410
PE O-36:4	QI05062	726.54290319999996	9.0847666670000002	NA
PE P-36:2 or PE O-36:3	QI05252	728.55898830000001	9.3388166669999997	HMDB0011441
PE P-36:1 or PE O-36:2	QI05513	730.57502539999996	9.6374499999999994	HMDB0011439
PE P-37:4 or PE O-37:5	QI05112	738.54307449999999	9.1694499999999994	NA
PE P-37:1 or PE O-37:2	QI05682	744.59074329999999	9.8157333330000007	NA
PE O-38:7	QI04892	748.52708689999997	8.7549333330000003	NA
PE P-38:6	QI04966	748.52774480000005	8.8708166669999997	HMDB0011420
PE P-38:5	QI05051	750.54321300000004	9.0580166670000004	HMDB0011387
PE P-38:4	QI05186	752.55938739999999	9.2541333330000004	HMDB0005779
PE P-38:3	QI05375	754.57444039999996	9.5081833329999998	HMDB0011384
PE P-38:2	QI05581	756.59066359999997	9.7176666669999996	HMDB0011382
PE P-38:1	QI05896	758.60651789999997	10.002933329999999	HMDB0011381
PE P-40:7	QI05010	774.54253630000005	8.9911666669999999	HMDB0011460
PE O-40:8	TF13	774.5432184	9.2546202530000006	NA
PE P-40:6 or PE O-40:7	QI05234	776.55931080000005	9.3031666669999993	HMDB0011394
PE P-40:4	QI05532	780.59066089999999	9.6597333330000001	HMDB0009610
PE P-40:2	QI05975	784.62235020000003	10.087616669999999	HMDB0011455
PE P-40:1	QI06220	786.6383409	10.36841667	HMDB0011363
PE P-42:6 or PE O-42:7	QI05447	804.59070540000005	9.5705833330000001	NA
PE P-42:5 or PE O-42:6	QI05670	806.60674549999999	9.8068166669999997	NA
PE P-42:4 or PE O-42:5_A	QI05862	808.62243950000004	9.9672666670000005	NA
PE P-42:4 or PE O-42:5_B	QI06223	808.62066119999997	10.36841667	NA
PE P-44:5 or PE O-44:6	TF15	834.63711839999996	10.2269697	NA
PI 34:1	TF18	837.54875939999999	8.7715822780000003	HMDB0009783
PI 32:1	TF16	809.51745940000001	8.3954594589999996	HMDB0009779
PI 34:0	TF17	839.56440940000005	9.1539873420000006	HMDB0009805
PI 36:4	QI04589	859.53385019999996	8.3760833330000004	HMDB0009789
PI 38:7	TF19	881.51745940000001	8.1256216220000006	NA
PI 38:6	QI04494	905.51494009999999	8.3003166670000006	NA
PI 38:4	QI04962	887.56490540000004	8.8619000000000003	HMDB0009815
PI 40:8	QI04717	907.53040869999995	8.5187000000000008	NA
PS 40:6	QI04952	836.54354490000003	8.8396166669999996	HMDB0010167
Cer 34:1;O2	QI04678	538.51953390000006	8.4919666669999998	HMDB0004949
Cer 36:1;O2	QI05006	566.55085340000005	8.9867000000000008	HMDB0004950
Cer 38:1;O2	QI05282	594.5823785	9.4145833329999995	HMDB0004951
Cer 38:0;O2	QI05394	596.59738500000003	9.5304666670000007	HMDB0011764
Cer 39:1;O2	QI05503	608.59794280000006	9.6329833330000003	HMDB0249814
Cer 40:2;O2	QI05356	620.59777959999997	9.4859000000000009	HMDB0011775
Cer 40:1;O2	QI05712	622.6137817	9.8424666670000001	HMDB0004952
Cer 40:0;O2	QI05842	624.6292201	9.9494500000000006	HMDB0011765
Cer 41:2;O2_A	QI05565	634.61311750000004	9.6953833330000005	NA
Cer 41:2;O2_B	QI05677	634.61339820000001	9.8201833329999992	NA
Cer 41:1;O2	QI05939	636.62960310000005	10.05195	HMDB0000950
Cer 42:3;O2	QI05492	646.61357210000006	9.6151666670000004	HMDB0240680
Cer 42:2;O2	QI05794	648.62931819999994	9.8959499999999991	HMDB0004953
Cer 42:1;O2	QI06112	650.64544860000001	10.25253333	HMDB0004956
Cer 42:0;O2	QI06208	652.66006379999999	10.355033329999999	HMDB0011768
Cer 43:2;O2	QI05973	662.64589909999995	10.087616669999999	NA
Cer 43:1;O2	TF20	664.66022039999996	10.41217172	HMDB0004957
HexCer 34:4;O2	QI04095	694.52488770000002	7.7253499999999997	NA
HexCer 34:1;O2	QI04446	700.57273450000002	8.2334499999999995	HMDB0004971
HexCer 36:2;O2_A	QI04598	726.5874354	8.3849999999999998	HMDB0004970
HexCer 36:2;O2_B	QI04761	726.58707990000005	8.5632833329999993	HMDB0004970
HexCer 36:1;O2	QI04881	728.60343780000005	8.7326499999999996	HMDB0004972
HexCer 38:5;O2	QI04625	748.56973019999998	8.4072833330000005	NA
HexCer 38:1;O2	QI05140	756.63510989999997	9.1872833329999999	HMDB0004973
HexCer 40:2;O2	QI05347	782.65056240000001	9.4725333329999994	NA
HexCer 40:1;O2	QI05481	784.66649600000005	9.6062499999999993	HMDB0004974
HexCer 41:2;O2	QI05557	796.66589759999999	9.6864666669999995	NA
HexCer 42:3;O2_B	QI05402	808.66584680000005	9.5304666670000007	NA
HexCer 42:3;O2_C	QI05612	808.66414599999996	9.7444166669999994	NA
HexCer 42:2;O2_A	QI05536	810.68229020000001	9.6552666669999994	HMDB0004975
HexCer 42:2;O2_B	QI05773	810.68214190000003	9.8825833329999995	HMDB0004975
HexCer 42:1;O2	QI05914	812.69825040000001	10.011850000000001	HMDB0004978
HexCer 43:3;O2	QI05837	822.6795654	9.9449833329999997	NA
HexCer 43:2;O2_A	QI05730	824.69723529999999	9.8513833329999994	NA
HexCer 43:2;O2_B	QI05968	824.69739460000005	10.08315	NA
HexCer 43:1;O2	QI06079	826.71383920000005	10.21241667	HMDB0004979
HexCer 44:5;O2	TF21	832.66609540000002	9.7275949369999992	NA
HexCer 44:4;O2	QI05921	834.68001130000005	10.016299999999999	NA
HexCer 44:3;O2	QI06014	836.69541100000004	10.1411	NA
HexCer 44:2;O2	QI05941	838.71403959999998	10.047499999999999	HMDB0004976
HexCer 44:1;O2	QI06264	840.72971600000005	10.412983329999999	HMDB0004977
HexCer 45:5;O2	QI05732	846.67949060000001	9.8469333330000008	NA
HexCer 46:5;O2	QI05958	860.69550200000003	10.060866669999999	NA
HexCer 46:4;O2	QI06265	862.71194930000001	10.412983329999999	NA
SM 32:1;O2	QI04142	675.54402359999995	7.8278499999999998	HMDB0012097
SM 33:1;O2	TF22	689.5592024	8.0841081080000006	HMDB0240608
SM 34:2;O2	QI04289	701.55923110000003	7.9927666669999997	HMDB0240613
SM 34:1;O2	QI04565	703.57507090000001	8.35825	HMDB0010169
SM 34:0;O2	QI04721	705.59061699999995	8.5320833329999992	HMDB0010168
SM 35:1;O2	QI04792	717.5895683	8.6078499999999991	HMDB0240622
SM 36:2;O2	QI04722	729.59037049999995	8.5276166670000002	HMDB0012101
SM 36:1;O2	QI04947	731.60648449999997	8.8396166669999996	HMDB0001348
SM 36:0;O2	QI05034	733.62121630000001	9.0178999999999991	HMDB0012087
SM 38:2;O2	QI05036	757.62223129999995	9.022366667	HMDB0240610
SM 38:1;O2	QI05224	759.63784220000002	9.2942499999999999	HMDB0012102
SM 39:1;O2	QI05386	773.65277060000005	9.5215666670000001	HMDB0240611
SM 40:2;O2	QI05277	785.65376570000001	9.3833833329999994	HMDB0012104
SM 40:1;O2	QI05610	787.66849869999999	9.7355	HMDB0012103
SM 41:2;O2	TF23	799.66875240000002	9.6672151900000003	HMDB0240614
SM 41:1;O2	QI05836	801.68479830000001	9.9449833329999997	HMDB0012105
SM 42:2;O2	TF24	813.68440239999995	9.777911392	HMDB0012107
SM 42:1;O2	QI06023	815.70030350000002	10.14555	HMDB0011697
SM 43:2;O2	QI05888	827.70092090000003	9.9850999999999992	HMDB0011699
SM 44:3;O2	QI05787	839.69979239999998	9.8915000000000006	NA
SM 44:2;O2	TF25	841.71570240000005	10.178232319999999	HMDB0013461
SM 44:1;O2	QI06332	843.73390040000004	10.493216670000001	HMDB0011698
CE 14:0	QI07353	619.54513340000005	11.741199999999999	HMDB0006725
CE 16:1	QI07427	645.55884409999999	11.82588333	HMDB0000658
CE 16:0	QI07664	647.57526889999997	12.133433330000001	HMDB0000885
CE 18:2	QI07505	671.57442179999998	11.92395	HMDB0000610
CE 18:1	QI07733	673.5899091	12.227033329999999	HMDB0000918
CE 18:0	QI07952	675.60602010000002	12.56576667	HMDB0010368
CE 19:2	QI07506	680.63446769999996	11.91948333	NA
CE 20:5	QI07146	693.55846540000005	11.513883330000001	HMDB0006731
CE 20:4	QI07379	695.57413080000003	11.77685	HMDB0006726
CE 20:3	QI07582	697.59001790000002	12.022	HMDB0006736
CE 22:6	QI07254	719.57407499999999	11.634233330000001	HMDB0006733
CE 22:4	QI07651	723.60530640000002	12.120050000000001	HMDB0006729
MG 14:0	QI01733	325.2349418	4.7524499999999996	HMDB0011561
MG 15:0	QI01975	339.25073900000001	5.0287833329999998	HMDB0011563
MG 16:1	QI01928	351.25072299999999	4.9842166670000001	HMDB0011565
MG 16:0	QI02276	353.2660783	5.3185000000000002	HMDB0011564
MG 17:0	QI02534	367.28215849999998	5.6349499999999999	HMDB0072856
MG 18:2_A	QI01978	377.26698110000001	5.0287833329999998	HMDB0011568
MG 18:1	QI02503	379.28206189999997	5.5770166669999997	HMDB0011567
MG 18:0	QI02844	381.2973824	5.969233333	HMDB0011131
MG 19:0	QI03002	395.31369530000001	6.3035166670000002	HMDB0072839
MG 20:4	QI02009	401.26652469999999	5.0644499999999999	HMDB0011578
MG 20:0	QI03275	409.3291079	6.6422666670000003	HMDB0011572
MG 22:1	QI03374	430.38959610000001	6.8205499999999999	HMDB0011582
MG 22:0	QI03606	437.36062179999999	7.315283333	HMDB0011581
MG 24:0	QI04119	465.39232879999997	7.783283333	HMDB0011588
DG 32:0	QI05231	591.49622450000004	9.2987000000000002	HMDB0007098
DG 34:2	QI05095	615.49588170000004	9.1605333330000001	HMDB0007103
DG 34:1	QI05310	617.51170260000004	9.432416667	HMDB0007102
DG 34:0	QI05605	619.52766020000001	9.7399500000000003	HMDB0007100
DG 35:1	QI05512	626.57215710000003	9.6418999999999997	HMDB0007387
DG 36:4	QI05096	639.49602760000005	9.1560833329999998	HMDB0007248
DG 36:3	QI05222	636.55671930000005	9.2853333330000005	HMDB0007219
DG 36:2	QI05423	643.52747209999995	9.5482999999999993	HMDB0007218
DG 36:1	QI05713	645.54328910000004	9.8424666670000001	HMDB0007216
DG 36:0	QI05997	647.55928640000002	10.118816669999999	HMDB0056036
DG 38:6	QI05054	658.54014070000005	9.071383333	HMDB0007257
DG 38:4	QI05442	667.52744229999996	9.5705833330000001	HMDB0007170
DG 38:3	QI05592	669.54306250000002	9.7265833330000007	HMDB0007169
DG 38:2	QI05829	671.5590287	9.9449833329999997	HMDB0007419
DG 38:1	QI06091	673.57499810000002	10.230233330000001	HMDB0007820
DG 40:5	QI05531	688.58765619999997	9.6552666669999994	HMDB0007738
TG 40:0	QI06502	712.64645480000001	10.698233330000001	HMDB0099325
TG 42:1	QI06584	738.66151009999999	10.823033329999999	HMDB0042068
TG 42:0	QI06787	745.63465919999999	11.09491667	HMDB0072780
TG 43:1	QI06730	757.63319300000001	11.014699999999999	HMDB0042098
TG 43:0	QI06891	759.64897259999998	11.224183330000001	HMDB0042062
TG 44:2	QI06698	769.63314230000003	10.97458333	HMDB0042279
TG 44:1	QI06861	771.6488008	11.18406667	HMDB0042301
TG 44:0	QI07035	773.66454880000003	11.38463333	HMDB0042063
TG 45:2	QI06849	783.6487707	11.166233330000001	HMDB0043170
TG 45:1	QI07004	785.66393819999996	11.348983329999999	HMDB0042099
TG 45:0	QI07171	787.67945840000004	11.53616667	HMDB0042093
TG 46:2	QI06977	797.66423910000003	11.317783329999999	HMDB0010419
TG 46:1	QI07133	799.67934190000005	11.50496667	HMDB0010412
TG 46:0	QI07319	801.69487360000005	11.701083329999999	HMDB0010411
TG 47:2	QI07120	811.67976080000005	11.47823333	HMDB0043199
TG 47:1	QI07283	813.69489950000002	11.660966670000001	HMDB0042100
TG 47:0	QI07451	815.71060650000004	11.85263333	HMDB0042094
TG 48:3	QI07095	823.68027840000002	11.45595	HMDB0005432
TG 48:2	QI07258	825.6950104	11.634233330000001	HMDB0005376
TG 48:1	QI07411	827.71044979999999	11.812516670000001	HMDB0005359
TG 48:0	QI07584	829.7261843	12.017533329999999	HMDB0005356
TG 49:3	QI07231	837.69590470000003	11.59856667	HMDB0042103
TG 49:2	QI07382	839.71103419999997	11.781316670000001	HMDB0011706
TG 49:1	QI07552	841.72639379999998	11.97743333	HMDB0011705
TG 49:0	QI07699	843.7421147	12.182449999999999	HMDB0042095
TG 50:4	QI07062	849.69433049999998	11.42028333	HMDB0005435
TG 50:3	QI07267	851.71087660000001	11.64315	HMDB0005433
TG 50:2	QI07471	853.72627309999996	11.874916669999999	HMDB0005377
TG 50:1	QI07654	855.74104409999995	12.115600000000001	HMDB0005360
TG 50:0	QI07827	857.75731229999997	12.3652	HMDB0005357
TG 51:3	QI07493	865.72751700000003	11.90165	HMDB0011701
TG 51:2	QI07626	867.74247849999995	12.0844	HMDB0011707
TG 51:1	QI07780	869.75805049999997	12.29388333	HMDB0042104
TG 51:0	QI07941	871.7738938	12.556850000000001	HMDB0031106
TG 52:6	QI07088	873.69443020000006	11.44703333	HMDB0005436
TG 52:5	QI07261	875.70940989999997	11.634233330000001	HMDB0005380
TG 52:4	QI07432	877.7265486	11.8348	HMDB0005363
TG 52:3	QI07541	879.74173280000002	11.95515	HMDB0005384
TG 52:2	QI07713	881.75752780000005	12.209199999999999	HMDB0005369
TG 52:1	QI07883	883.77305360000003	12.4588	HMDB0005367
TG 52:0	QI08045	885.78873290000001	12.739599999999999	HMDB0005365
TG 53:4	QI07444	886.78656839999996	11.843716669999999	HMDB0044711
TG 53:2	QI07843	895.77420919999997	12.40085	HMDB0062701
TG 53:1	QI07993	897.78976580000005	12.65491667	HMDB0042482
TG 54:7	TF27	899.70991140000001	11.338181820000001	HMDB0005447
TG 54:6	QI07365	901.7257042	11.754566670000001	HMDB0005391
TG 54:5	QI07519	903.74185820000002	11.9284	HMDB0005385
TG 54:4	QI07682	905.75690169999996	12.164633329999999	HMDB0005370
TG 54:3	QI07797	907.77146300000004	12.316166669999999	HMDB0005405
TG 54:2	QI07954	909.78892829999995	12.56576667	HMDB0005403
TG 54:1	QI08101	911.80469919999996	12.82873333	HMDB0005395
TG 54:0	QI08272	913.82058400000005	13.163016669999999	HMDB0005393
TG 55:7	QI07174	908.77098890000002	11.53616667	HMDB0049739
TG 55:6	QI07366	910.7862341	11.750116670000001	HMDB0044720
TG 55:5	QI07508	912.80156669999997	11.91948333	HMDB0044719
TG 55:4	QI07683	914.81744930000002	12.164633329999999	HMDB0044713
TG 55:3	QI07783	916.83253219999995	12.3028	HMDB0043127
TG 56:8	QI07245	925.72619210000005	11.616400000000001	HMDB0005392
TG 56:7	QI07434	927.74184879999996	11.8348	HMDB0005462
TG 56:6	QI07619	929.75740029999997	12.071033330000001	HMDB0005456
TG 56:5	QI07759	931.77276710000001	12.26713333	HMDB0005406
TG 56:4	TF28	933.78816140000004	12.38638298	HMDB0005398
TG 56:3	QI08001	935.80457019999994	12.663816669999999	HMDB0005410
TG 56:2	QI08164	937.82084380000003	12.949083330000001	HMDB0005404
TG 56:1	TF29	939.83511139999996	13.23	HMDB0005396
TG 57:8	QI07262	934.78626269999995	11.62976667	HMDB0054025
TG 58:10	QI07210	949.7262743	11.58075	HMDB0005476
TG 58:9	QI07330	951.74156679999999	11.714449999999999	HMDB0005463
TG 58:8	QI07510	953.7576292	11.92395	HMDB0005413
TG 58:7	QI07684	955.77310320000004	12.15571667	HMDB0005471
TG 58:6_A	QI07762	952.833662	12.271599999999999	HMDB0005458
TG 58:6_B	QI07856	957.78886639999996	12.40976667	HMDB0005458
TG 58:5	QI07923	959.80435699999998	12.516733329999999	HMDB0042645
TG 58:1	QI08622	962.91207259999999	13.81821667	HMDB0043925
TG 60:12	QI07137	973.72655199999997	11.496066669999999	HMDB0005478
TG 60:11	QI07297	975.7414387	11.669883329999999	HMDB0050099
TG 62:13	QI07226	999.74162579999995	11.5852	HMDB0050279
TG 62:12	QI07400	1001.7573630000001	11.799149999999999	HMDB0045449
Piperine	TF30	286.14377039999999	3.65	HMDB0029377
Linoleoyl-EA	QI01907	324.28954399999998	4.9485666669999997	HMDB0012252
Palmitoyl-EA	QI02041	300.28984839999998	5.1045666670000003	HMDB0002100
Oleoyl-EA	QI02206	326.30556360000003	5.2873000000000001	HMDB0002088
Coenzyme Q9	QI06822	795.62912070000004	11.12611667	HMDB0006707
Coenzyme Q10	QI07345	885.67378480000002	11.727833329999999	HMDB0001072
alpha-Tocopherol	TF31	430.3805314	8.0529729729999993	HMDB0001893
Sphingosine	QI01264	300.28972540000001	4.3022833330000001	HMDB0000252
14-Demethyllanosterol	TF32	395.36722639999999	7.7104864859999998	HMDB0304021
7-Dehydro-desmosterol	TF33	383.3308414	6.8490810809999996	HMDB0003896
Cholestenone	QI03591	385.34665469999999	7.2930000000000001	HMDB0000921
Cholesterol	QI03801	369.3517195	7.5114000000000001	HMDB0000067
Lanosterol	QI04034	409.38274239999998	7.6495666670000002	HMDB0001251
5-cholesten-3-one	QI03877	385.34615220000001	7.5515166669999996	NA
MG 14:1	QI01361	318.26398929999999	4.3914166669999997	HMDB0011562
MG 18:2_B	QI02076	377.2666749	5.1268500000000001	HMDB0011568
DG 38:5	QI05197	665.5100486	9.2719666669999992	HMDB0007199
TG 46:3	QI06806	790.69342470000004	11.11275	HMDB0042751
TG 58:2	QI08389	960.89777849999996	13.390333330000001	HMDB0044121
PE P-32:1	QI04922	674.51091750000001	8.7861333330000004	HMDB0011339
CE 22:5	TF26	721.58940140000004	11.82555556	HMDB0010375
METABOLITES_END
#END