#METABOLOMICS WORKBENCH AnnalauraM_20250523_030315 DATATRACK_ID:5942 STUDY_ID:ST003929 ANALYSIS_ID:AN006452 PROJECT_ID:PR002461
VERSION             	1
CREATED_ON             	May 24, 2025, 3:17 am
#PROJECT
PR:PROJECT_TITLE                 	Imidazole propionate is a driver and therapeutic target in atherosclerosis
PR:PROJECT_TYPE                  	Original research
PR:PROJECT_SUMMARY               	Atherosclerosis (AT) is the main underlying cause of cardiovascular diseases
PR:PROJECT_SUMMARY               	(CVDs). Its prevention is based on the detection and treatment of traditional
PR:PROJECT_SUMMARY               	cardiovascular risk factors but often fails to identify individuals at risk for
PR:PROJECT_SUMMARY               	early vascular disease. Recent research has suggested new players in the
PR:PROJECT_SUMMARY               	pathophysiology of atherosclerosis, highlighting the need for alternative
PR:PROJECT_SUMMARY               	disease biomarkers and therapeutic targets to improve early diagnosis and
PR:PROJECT_SUMMARY               	therapy efficacy. Here, we identified that microbially produced imidazole
PR:PROJECT_SUMMARY               	propionate (ImP) is associated with the extent of atherosclerosis in mice and in
PR:PROJECT_SUMMARY               	two independent human cohorts. Furthermore, ImP administration to
PR:PROJECT_SUMMARY               	atherosclerosis-prone mice fed chow diet was sufficient to induce
PR:PROJECT_SUMMARY               	atherosclerosis without altering the lipid profile, and it was linked to
PR:PROJECT_SUMMARY               	activation of both systemic and local innate and adaptive immunity and
PR:PROJECT_SUMMARY               	inflammation. Specifically, we found that ImP caused atherosclerosis through
PR:PROJECT_SUMMARY               	Imidazoline-1 receptor (I1R) expressed in myeloid cells. Blocking this ImP/I1R
PR:PROJECT_SUMMARY               	axis inhibited the development of atherosclerosis induced by ImP as well as by
PR:PROJECT_SUMMARY               	high cholesterol diet in mice. Identification of the strong association of ImP
PR:PROJECT_SUMMARY               	with active atherosclerosis, along with the discovery of the contribution of the
PR:PROJECT_SUMMARY               	ImP/I1R axis to disease progression opens new avenues for improving the early
PR:PROJECT_SUMMARY               	diagnosis and personalized therapy of atherosclerosis.
PR:INSTITUTE                     	Centro Nacional de Investigaciones Cardiovasculares Carlos III
PR:LAST_NAME                     	Mastrangelo
PR:FIRST_NAME                    	Annalaura
PR:ADDRESS                       	Calle de Melchor Fernández Almagro, 3 – 28029, Madrid (Spain)
PR:EMAIL                         	amastrangelo@gmail.com
PR:PHONE                         	+34914531202
#STUDY
ST:STUDY_TITLE                   	Imidazole propionate is a driver and therapeutic target in atherosclerosis
ST:STUDY_TITLE                   	(study 1)
ST:STUDY_SUMMARY                 	Atherosclerosis (AT) is the leading underlying cause of cardiovascular diseases
ST:STUDY_SUMMARY                 	(CVDs). While current preventive strategies focus on identifying and managing
ST:STUDY_SUMMARY                 	traditional cardiovascular risk factors, they often fail to detect individuals
ST:STUDY_SUMMARY                 	at risk of early-stage vascular disease. Recent studies have uncovered novel
ST:STUDY_SUMMARY                 	contributors to the pathophysiology of atherosclerosis, underscoring the need
ST:STUDY_SUMMARY                 	for alternative biomarkers and therapeutic targets to enhance early diagnosis
ST:STUDY_SUMMARY                 	and treatment. In this study, we identified a strong association between the
ST:STUDY_SUMMARY                 	microbial metabolite imidazole propionate (ImP) and atherosclerosis burden in
ST:STUDY_SUMMARY                 	mice. To explore the translational relevance of these findings in humans, we
ST:STUDY_SUMMARY                 	quantified ImP and its biosynthetic precursors (histidine and urocanic acid)in
ST:STUDY_SUMMARY                 	plasma samples from a subcohort of the PESA study (N = 400). Our analysis
ST:STUDY_SUMMARY                 	revealed a significant relationship between circulating ImP levels and the
ST:STUDY_SUMMARY                 	presence of subclinical atherosclerosis, supporting its potential role as a
ST:STUDY_SUMMARY                 	novel biomarker for early atherosclerotic disease.
ST:INSTITUTE                     	Centro Nacional de Investigaciones Cardiovasculares Carlos III
ST:LAST_NAME                     	Mastrangelo
ST:FIRST_NAME                    	Annalaura
ST:ADDRESS                       	Calle de Melchor Fernández Almagro, 3 – 28029, Madrid (Spain)
ST:EMAIL                         	amastrangelo@cnic.es
ST:PHONE                         	+34914531202
#SUBJECT
SU:SUBJECT_TYPE                  	Human
SU:SUBJECT_SPECIES               	Homo sapiens
SU:TAXONOMY_ID                   	9606
SU:GENDER                        	Male and female
#SUBJECT_SAMPLE_FACTORS:         	SUBJECT(optional)[tab]SAMPLE[tab]FACTORS(NAME:VALUE pairs separated by |)[tab]Raw file names and additional sample data
SUBJECT_SAMPLE_FACTORS           	263	R1_A1_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_A1_5.mzML
SUBJECT_SAMPLE_FACTORS           	1199	R1_A10_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_A10_2.mzML
SUBJECT_SAMPLE_FACTORS           	1896	R1_A11_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_A11_5.mzML
SUBJECT_SAMPLE_FACTORS           	204	R1_A12_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_A12_4.mzML
SUBJECT_SAMPLE_FACTORS           	642	R1_A2_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_A2_2.mzML
SUBJECT_SAMPLE_FACTORS           	715	R1_A3_4	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_A3_4.mzML
SUBJECT_SAMPLE_FACTORS           	41	R1_A4_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_A4_2.mzML
SUBJECT_SAMPLE_FACTORS           	2	R1_A5_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_A5_5.mzML
SUBJECT_SAMPLE_FACTORS           	452	R1_A6_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_A6_4.mzML
SUBJECT_SAMPLE_FACTORS           	535	R1_A7_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_A7_5.mzML
SUBJECT_SAMPLE_FACTORS           	134	R1_A8_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_A8_5.mzML
SUBJECT_SAMPLE_FACTORS           	3350	R1_A9_4	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_A9_4.mzML
SUBJECT_SAMPLE_FACTORS           	1013	R1_B1_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_B1_5.mzML
SUBJECT_SAMPLE_FACTORS           	724	R1_B10_3	AT:1 | FDG:3 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_B10_3.mzML
SUBJECT_SAMPLE_FACTORS           	2390	R1_B11_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_B11_2.mzML
SUBJECT_SAMPLE_FACTORS           	1520	R1_B12_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_B12_2.mzML
SUBJECT_SAMPLE_FACTORS           	1259	R1_B2_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_B2_1.mzML
SUBJECT_SAMPLE_FACTORS           	752	R1_B3_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_B3_5.mzML
SUBJECT_SAMPLE_FACTORS           	2179	R1_B4_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_B4_5.mzML
SUBJECT_SAMPLE_FACTORS           	862	R1_B7_3	AT:1 | FDG:3 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_B7_3.mzML
SUBJECT_SAMPLE_FACTORS           	2212	R1_B8_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_B8_4.mzML
SUBJECT_SAMPLE_FACTORS           	684	R1_B9_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_B9_1.mzML
SUBJECT_SAMPLE_FACTORS           	1311	R1_C1_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_C1_1.mzML
SUBJECT_SAMPLE_FACTORS           	1286	R1_C10_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_C10_2.mzML
SUBJECT_SAMPLE_FACTORS           	3722	R1_C11_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_C11_5.mzML
SUBJECT_SAMPLE_FACTORS           	3867	R1_C12_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_C12_5.mzML
SUBJECT_SAMPLE_FACTORS           	3695	R1_C2_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_C2_4.mzML
SUBJECT_SAMPLE_FACTORS           	624	R1_C3_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_C3_5.mzML
SUBJECT_SAMPLE_FACTORS           	1000	R1_C4_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_C4_5.mzML
SUBJECT_SAMPLE_FACTORS           	3343	R1_C5_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_C5_2.mzML
SUBJECT_SAMPLE_FACTORS           	918	R1_C6_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_C6_5.mzML
SUBJECT_SAMPLE_FACTORS           	3804	R1_C7_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_C7_4.mzML
SUBJECT_SAMPLE_FACTORS           	194	R1_C8_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_C8_5.mzML
SUBJECT_SAMPLE_FACTORS           	3120	R1_C9_3	AT:1 | FDG:3 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_C9_3.mzML
SUBJECT_SAMPLE_FACTORS           	3656	R1_D1_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_D1_5.mzML
SUBJECT_SAMPLE_FACTORS           	3204	R1_D10_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_D10_2.mzML
SUBJECT_SAMPLE_FACTORS           	494	R1_D11_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_D11_4.mzML
SUBJECT_SAMPLE_FACTORS           	344	R1_D12_3	AT:1 | FDG:3 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_D12_3.mzML
SUBJECT_SAMPLE_FACTORS           	2285	R1_D3_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_D3_5.mzML
SUBJECT_SAMPLE_FACTORS           	767	R1_D4_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_D4_2.mzML
SUBJECT_SAMPLE_FACTORS           	136	R1_D5_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_D5_1.mzML
SUBJECT_SAMPLE_FACTORS           	2497	R1_D6_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_D6_5.mzML
SUBJECT_SAMPLE_FACTORS           	163	R1_D7_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_D7_5.mzML
SUBJECT_SAMPLE_FACTORS           	2744	R1_D9_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_D9_2.mzML
SUBJECT_SAMPLE_FACTORS           	2813	R1_E1_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_E1_2.mzML
SUBJECT_SAMPLE_FACTORS           	16	R1_E11_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_E11_5.mzML
SUBJECT_SAMPLE_FACTORS           	1486	R1_E12_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_E12_2.mzML
SUBJECT_SAMPLE_FACTORS           	1035	R1_E2_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_E2_2.mzML
SUBJECT_SAMPLE_FACTORS           	31	R1_E3_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_E3_1.mzML
SUBJECT_SAMPLE_FACTORS           	1964	R1_E4_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_E4_5.mzML
SUBJECT_SAMPLE_FACTORS           	1525	R1_E5_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_E5_5.mzML
SUBJECT_SAMPLE_FACTORS           	96	R1_E6_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_E6_4.mzML
SUBJECT_SAMPLE_FACTORS           	83	R1_E7_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_E7_2.mzML
SUBJECT_SAMPLE_FACTORS           	4043	R1_E8_4	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_E8_4.mzML
SUBJECT_SAMPLE_FACTORS           	936	R1_E9_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_E9_4.mzML
SUBJECT_SAMPLE_FACTORS           	1029	R1_F1_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_F1_5.mzML
SUBJECT_SAMPLE_FACTORS           	264	R1_F10_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_F10_5.mzML
SUBJECT_SAMPLE_FACTORS           	2476	R1_F11_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_F11_5.mzML
SUBJECT_SAMPLE_FACTORS           	1087	R1_F12_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_F12_2.mzML
SUBJECT_SAMPLE_FACTORS           	3418	R1_F2_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_F2_2.mzML
SUBJECT_SAMPLE_FACTORS           	469	R1_F3_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_F3_2.mzML
SUBJECT_SAMPLE_FACTORS           	701	R1_F4_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_F4_2.mzML
SUBJECT_SAMPLE_FACTORS           	3781	R1_F5_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_F5_2.mzML
SUBJECT_SAMPLE_FACTORS           	150	R1_F6_3	AT:1 | FDG:3 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_F6_3.mzML
SUBJECT_SAMPLE_FACTORS           	2892	R1_F9_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_F9_5.mzML
SUBJECT_SAMPLE_FACTORS           	4136	R1_G1_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_G1_1.mzML
SUBJECT_SAMPLE_FACTORS           	545	R1_G10_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_G10_5.mzML
SUBJECT_SAMPLE_FACTORS           	634	R1_G11_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_G11_5.mzML
SUBJECT_SAMPLE_FACTORS           	892	R1_G2_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_G2_2.mzML
SUBJECT_SAMPLE_FACTORS           	296	R1_G3_3	AT:1 | FDG:3 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_G3_3.mzML
SUBJECT_SAMPLE_FACTORS           	700	R1_G4_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_G4_5.mzML
SUBJECT_SAMPLE_FACTORS           	445	R1_G5_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_G5_5.mzML
SUBJECT_SAMPLE_FACTORS           	1529	R1_G6_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_G6_4.mzML
SUBJECT_SAMPLE_FACTORS           	144	R1_G8_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_G8_5.mzML
SUBJECT_SAMPLE_FACTORS           	1772	R1_H10_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_H10_5.mzML
SUBJECT_SAMPLE_FACTORS           	25	R1_H11_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_H11_1.mzML
SUBJECT_SAMPLE_FACTORS           	373	R1_H2_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_H2_2.mzML
SUBJECT_SAMPLE_FACTORS           	91	R1_H3_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_H3_2.mzML
SUBJECT_SAMPLE_FACTORS           	118	R1_H4_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_H4_4.mzML
SUBJECT_SAMPLE_FACTORS           	635	R1_H5_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_H5_1.mzML
SUBJECT_SAMPLE_FACTORS           	4134	R1_H6_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_H6_5.mzML
SUBJECT_SAMPLE_FACTORS           	2540	R1_H7_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_H7_4.mzML
SUBJECT_SAMPLE_FACTORS           	4139	R1_H8_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_H8_4.mzML
SUBJECT_SAMPLE_FACTORS           	1097	R1_H9_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R1_H9_5.mzML
SUBJECT_SAMPLE_FACTORS           	2141	R2_A1_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_A1_4.mzML
SUBJECT_SAMPLE_FACTORS           	881	R2_A10_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_A10_4.mzML
SUBJECT_SAMPLE_FACTORS           	2091	R2_A11_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_A11_4.mzML
SUBJECT_SAMPLE_FACTORS           	618	R2_A12_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_A12_2.mzML
SUBJECT_SAMPLE_FACTORS           	3523	R2_A2_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_A2_2.mzML
SUBJECT_SAMPLE_FACTORS           	486	R2_A3_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_A3_5.mzML
SUBJECT_SAMPLE_FACTORS           	1560	R2_A4_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_A4_5.mzML
SUBJECT_SAMPLE_FACTORS           	559	R2_A5_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_A5_2.mzML
SUBJECT_SAMPLE_FACTORS           	3427	R2_A6_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_A6_5.mzML
SUBJECT_SAMPLE_FACTORS           	530	R2_A7_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_A7_4.mzML
SUBJECT_SAMPLE_FACTORS           	3756	R2_A8_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_A8_2.mzML
SUBJECT_SAMPLE_FACTORS           	1294	R2_A9_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_A9_4.mzML
SUBJECT_SAMPLE_FACTORS           	2879	R2_B1_4	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_B1_4.mzML
SUBJECT_SAMPLE_FACTORS           	588	R2_B10_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_B10_2.mzML
SUBJECT_SAMPLE_FACTORS           	1120	R2_B11_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_B11_5.mzML
SUBJECT_SAMPLE_FACTORS           	1684	R2_B12_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_B12_5.mzML
SUBJECT_SAMPLE_FACTORS           	2533	R2_B2_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_B2_5.mzML
SUBJECT_SAMPLE_FACTORS           	2035	R2_B3_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_B3_4.mzML
SUBJECT_SAMPLE_FACTORS           	1548	R2_B4_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_B4_2.mzML
SUBJECT_SAMPLE_FACTORS           	3588	R2_B5_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_B5_2.mzML
SUBJECT_SAMPLE_FACTORS           	1223	R2_B6_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_B6_4.mzML
SUBJECT_SAMPLE_FACTORS           	2173	R2_B7_2	AT:1 | FDG:3 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_B7_2.mzML
SUBJECT_SAMPLE_FACTORS           	177	R2_B8_3	AT:1 | FDG:3 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_B8_3.mzML
SUBJECT_SAMPLE_FACTORS           	3405	R2_B9_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_B9_5.mzML
SUBJECT_SAMPLE_FACTORS           	3950	R2_C1_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_C1_5.mzML
SUBJECT_SAMPLE_FACTORS           	1544	R2_C10_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_C10_5.mzML
SUBJECT_SAMPLE_FACTORS           	265	R2_C11_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_C11_5.mzML
SUBJECT_SAMPLE_FACTORS           	1840	R2_C12_3	AT:1 | FDG:3 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_C12_3.mzML
SUBJECT_SAMPLE_FACTORS           	682	R2_C2_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_C2_2.mzML
SUBJECT_SAMPLE_FACTORS           	3190	R2_C3_3	AT:1 | FDG:3 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_C3_3.mzML
SUBJECT_SAMPLE_FACTORS           	3115	R2_C4_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_C4_1.mzML
SUBJECT_SAMPLE_FACTORS           	2884	R2_C5_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_C5_2.mzML
SUBJECT_SAMPLE_FACTORS           	910	R2_C6_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_C6_4.mzML
SUBJECT_SAMPLE_FACTORS           	1856	R2_C7_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_C7_4.mzML
SUBJECT_SAMPLE_FACTORS           	2159	R2_C8_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_C8_2.mzML
SUBJECT_SAMPLE_FACTORS           	2563	R2_C9_3	AT:1 | FDG:3 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_C9_3.mzML
SUBJECT_SAMPLE_FACTORS           	628	R2_D1_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_D1_4.mzML
SUBJECT_SAMPLE_FACTORS           	2762	R2_D10_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_D10_2.mzML
SUBJECT_SAMPLE_FACTORS           	34	R2_D11_3	AT:1 | FDG:3 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_D11_3.mzML
SUBJECT_SAMPLE_FACTORS           	1418	R2_D12_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_D12_5.mzML
SUBJECT_SAMPLE_FACTORS           	61	R2_D3_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_D3_4.mzML
SUBJECT_SAMPLE_FACTORS           	1835	R2_D4_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_D4_1.mzML
SUBJECT_SAMPLE_FACTORS           	76	R2_D5_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_D5_5.mzML
SUBJECT_SAMPLE_FACTORS           	972	R2_D6_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_D6_5.mzML
SUBJECT_SAMPLE_FACTORS           	3197	R2_D8_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_D8_5.mzML
SUBJECT_SAMPLE_FACTORS           	3332	R2_D9_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_D9_4.mzML
SUBJECT_SAMPLE_FACTORS           	3251	R2_E1_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_E1_5.mzML
SUBJECT_SAMPLE_FACTORS           	3941	R2_E10_4	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_E10_4.mzML
SUBJECT_SAMPLE_FACTORS           	127	R2_E11_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_E11_5.mzML
SUBJECT_SAMPLE_FACTORS           	7	R2_E3_3	AT:1 | FDG:3 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_E3_3.mzML
SUBJECT_SAMPLE_FACTORS           	59	R2_E4_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_E4_5.mzML
SUBJECT_SAMPLE_FACTORS           	706	R2_E5_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_E5_5.mzML
SUBJECT_SAMPLE_FACTORS           	3057	R2_E6_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_E6_5.mzML
SUBJECT_SAMPLE_FACTORS           	1635	R2_E7_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_E7_4.mzML
SUBJECT_SAMPLE_FACTORS           	1148	R2_E8_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_E8_4.mzML
SUBJECT_SAMPLE_FACTORS           	2280	R2_E9_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_E9_5.mzML
SUBJECT_SAMPLE_FACTORS           	2220	R2_F1_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_F1_5.mzML
SUBJECT_SAMPLE_FACTORS           	1983	R2_F10_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_F10_5.mzML
SUBJECT_SAMPLE_FACTORS           	678	R2_F12_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_F12_4.mzML
SUBJECT_SAMPLE_FACTORS           	658	R2_F2_3	AT:1 | FDG:3 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_F2_3.mzML
SUBJECT_SAMPLE_FACTORS           	1700	R2_F3_2	AT:1 | FDG:3 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_F3_2.mzML
SUBJECT_SAMPLE_FACTORS           	29	R2_F4_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_F4_2.mzML
SUBJECT_SAMPLE_FACTORS           	691	R2_F5_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_F5_2.mzML
SUBJECT_SAMPLE_FACTORS           	4168	R2_F6_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_F6_4.mzML
SUBJECT_SAMPLE_FACTORS           	1365	R2_F7_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_F7_2.mzML
SUBJECT_SAMPLE_FACTORS           	28	R2_F8_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_F8_2.mzML
SUBJECT_SAMPLE_FACTORS           	3325	R2_F9_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_F9_2.mzML
SUBJECT_SAMPLE_FACTORS           	4177	R2_G1_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_G1_5.mzML
SUBJECT_SAMPLE_FACTORS           	3071	R2_G10_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_G10_5.mzML
SUBJECT_SAMPLE_FACTORS           	569	R2_G11_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_G11_2.mzML
SUBJECT_SAMPLE_FACTORS           	771	R2_G12_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_G12_5.mzML
SUBJECT_SAMPLE_FACTORS           	1759	R2_G2_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_G2_2.mzML
SUBJECT_SAMPLE_FACTORS           	638	R2_G3_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_G3_4.mzML
SUBJECT_SAMPLE_FACTORS           	3133	R2_G6_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_G6_2.mzML
SUBJECT_SAMPLE_FACTORS           	1011	R2_G7_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_G7_4.mzML
SUBJECT_SAMPLE_FACTORS           	2169	R2_G8_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_G8_2.mzML
SUBJECT_SAMPLE_FACTORS           	2906	R2_G9_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_G9_2.mzML
SUBJECT_SAMPLE_FACTORS           	2916	R2_H1_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_H1_5.mzML
SUBJECT_SAMPLE_FACTORS           	3916	R2_H10_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_H10_5.mzML
SUBJECT_SAMPLE_FACTORS           	2087	R2_H11_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_H11_4.mzML
SUBJECT_SAMPLE_FACTORS           	2976	R2_H12_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_H12_4.mzML
SUBJECT_SAMPLE_FACTORS           	3998	R2_H2_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_H2_5.mzML
SUBJECT_SAMPLE_FACTORS           	709	R2_H3_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_H3_4.mzML
SUBJECT_SAMPLE_FACTORS           	1937	R2_H4_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_H4_4.mzML
SUBJECT_SAMPLE_FACTORS           	1659	R2_H5_2	AT:1 | FDG:3 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_H5_2.mzML
SUBJECT_SAMPLE_FACTORS           	397	R2_H6_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_H6_5.mzML
SUBJECT_SAMPLE_FACTORS           	827	R2_H7_3	AT:1 | FDG:3 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_H7_3.mzML
SUBJECT_SAMPLE_FACTORS           	1316	R2_H8_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_H8_2.mzML
SUBJECT_SAMPLE_FACTORS           	1555	R2_H9_3	AT:1 | FDG:3 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R2_H9_3.mzML
SUBJECT_SAMPLE_FACTORS           	3849	R3_A1_3	AT:1 | FDG:3 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_A1_3.mzML
SUBJECT_SAMPLE_FACTORS           	505	R3_A10_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_A10_5.mzML
SUBJECT_SAMPLE_FACTORS           	2331	R3_A11_3	AT:1 | FDG:3 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_A11_3.mzML
SUBJECT_SAMPLE_FACTORS           	2036	R3_A12_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_A12_2.mzML
SUBJECT_SAMPLE_FACTORS           	1371	R3_A2_3	AT:1 | FDG:3 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_A2_3.mzML
SUBJECT_SAMPLE_FACTORS           	4229	R3_A3_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_A3_5.mzML
SUBJECT_SAMPLE_FACTORS           	1221	R3_A4_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_A4_2.mzML
SUBJECT_SAMPLE_FACTORS           	939	R3_A5_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_A5_5.mzML
SUBJECT_SAMPLE_FACTORS           	3433	R3_A6_2	AT:1 | FDG:3 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_A6_2.mzML
SUBJECT_SAMPLE_FACTORS           	1407	R3_A7_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_A7_2.mzML
SUBJECT_SAMPLE_FACTORS           	148	R3_A8_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_A8_1.mzML
SUBJECT_SAMPLE_FACTORS           	1752	R3_A9_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_A9_2.mzML
SUBJECT_SAMPLE_FACTORS           	1625	R3_B1_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_B1_2.mzML
SUBJECT_SAMPLE_FACTORS           	3079	R3_B10_3	AT:1 | FDG:3 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_B10_3.mzML
SUBJECT_SAMPLE_FACTORS           	1230	R3_B12_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_B12_5.mzML
SUBJECT_SAMPLE_FACTORS           	924	R3_B2_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_B2_5.mzML
SUBJECT_SAMPLE_FACTORS           	1649	R3_B3_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_B3_1.mzML
SUBJECT_SAMPLE_FACTORS           	1736	R3_B4_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_B4_2.mzML
SUBJECT_SAMPLE_FACTORS           	3546	R3_B5_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_B5_5.mzML
SUBJECT_SAMPLE_FACTORS           	3838	R3_B6_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_B6_5.mzML
SUBJECT_SAMPLE_FACTORS           	1791	R3_B7_3	AT:1 | FDG:3 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_B7_3.mzML
SUBJECT_SAMPLE_FACTORS           	592	R3_B8_3	AT:1 | FDG:3 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_B8_3.mzML
SUBJECT_SAMPLE_FACTORS           	2158	R3_B9_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_B9_5.mzML
SUBJECT_SAMPLE_FACTORS           	3408	R3_C1_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_C1_4.mzML
SUBJECT_SAMPLE_FACTORS           	867	R3_C10_4	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_C10_4.mzML
SUBJECT_SAMPLE_FACTORS           	1018	R3_C11_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_C11_5.mzML
SUBJECT_SAMPLE_FACTORS           	1699	R3_C12_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_C12_5.mzML
SUBJECT_SAMPLE_FACTORS           	2061	R3_C2_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_C2_2.mzML
SUBJECT_SAMPLE_FACTORS           	3036	R3_C3_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_C3_4.mzML
SUBJECT_SAMPLE_FACTORS           	92	R3_C4_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_C4_4.mzML
SUBJECT_SAMPLE_FACTORS           	239	R3_C5_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_C5_5.mzML
SUBJECT_SAMPLE_FACTORS           	64	R3_C6_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_C6_2.mzML
SUBJECT_SAMPLE_FACTORS           	1458	R3_C7_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_C7_5.mzML
SUBJECT_SAMPLE_FACTORS           	975	R3_C8_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_C8_5.mzML
SUBJECT_SAMPLE_FACTORS           	1872	R3_C9_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_C9_5.mzML
SUBJECT_SAMPLE_FACTORS           	4133	R3_D1_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_D1_2.mzML
SUBJECT_SAMPLE_FACTORS           	2255	R3_D10_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_D10_2.mzML
SUBJECT_SAMPLE_FACTORS           	1135	R3_D12_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_D12_2.mzML
SUBJECT_SAMPLE_FACTORS           	930	R3_D2_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_D2_1.mzML
SUBJECT_SAMPLE_FACTORS           	707	R3_D3_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_D3_5.mzML
SUBJECT_SAMPLE_FACTORS           	1355	R3_D4_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_D4_5.mzML
SUBJECT_SAMPLE_FACTORS           	977	R3_D5_3	AT:1 | FDG:3 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_D5_3.mzML
SUBJECT_SAMPLE_FACTORS           	1215	R3_D6_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_D6_5.mzML
SUBJECT_SAMPLE_FACTORS           	3619	R3_D7_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_D7_5.mzML
SUBJECT_SAMPLE_FACTORS           	1848	R3_D8_4	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_D8_4.mzML
SUBJECT_SAMPLE_FACTORS           	210	R3_E1_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_E1_4.mzML
SUBJECT_SAMPLE_FACTORS           	871	R3_E10_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_E10_5.mzML
SUBJECT_SAMPLE_FACTORS           	2157	R3_E11_4	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_E11_4.mzML
SUBJECT_SAMPLE_FACTORS           	3487	R3_E12_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_E12_5.mzML
SUBJECT_SAMPLE_FACTORS           	4050	R3_E2_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_E2_5.mzML
SUBJECT_SAMPLE_FACTORS           	58	R3_E3_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_E3_2.mzML
SUBJECT_SAMPLE_FACTORS           	14	R3_E4_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_E4_4.mzML
SUBJECT_SAMPLE_FACTORS           	1682	R3_E7_3	AT:1 | FDG:3 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_E7_3.mzML
SUBJECT_SAMPLE_FACTORS           	4035	R3_E8_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_E8_2.mzML
SUBJECT_SAMPLE_FACTORS           	2112	R3_E9_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_E9_5.mzML
SUBJECT_SAMPLE_FACTORS           	1080	R3_F1_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_F1_2.mzML
SUBJECT_SAMPLE_FACTORS           	2388	R3_F10_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_F10_1.mzML
SUBJECT_SAMPLE_FACTORS           	2044	R3_F11_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_F11_5.mzML
SUBJECT_SAMPLE_FACTORS           	2262	R3_F12_3	AT:1 | FDG:3 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_F12_3.mzML
SUBJECT_SAMPLE_FACTORS           	2293	R3_F2_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_F2_1.mzML
SUBJECT_SAMPLE_FACTORS           	1028	R3_F3_4	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_F3_4.mzML
SUBJECT_SAMPLE_FACTORS           	1276	R3_F4_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_F4_5.mzML
SUBJECT_SAMPLE_FACTORS           	605	R3_F6_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_F6_5.mzML
SUBJECT_SAMPLE_FACTORS           	1746	R3_F7_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_F7_5.mzML
SUBJECT_SAMPLE_FACTORS           	3100	R3_F8_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_F8_5.mzML
SUBJECT_SAMPLE_FACTORS           	3012	R3_F9_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_F9_1.mzML
SUBJECT_SAMPLE_FACTORS           	363	R3_G1_2	AT:1 | FDG:3 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_G1_2.mzML
SUBJECT_SAMPLE_FACTORS           	2782	R3_G10_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_G10_5.mzML
SUBJECT_SAMPLE_FACTORS           	906	R3_G11_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_G11_4.mzML
SUBJECT_SAMPLE_FACTORS           	2723	R3_G12_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_G12_5.mzML
SUBJECT_SAMPLE_FACTORS           	254	R3_G2_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_G2_5.mzML
SUBJECT_SAMPLE_FACTORS           	570	R3_G3_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_G3_2.mzML
SUBJECT_SAMPLE_FACTORS           	2562	R3_G4_4	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_G4_4.mzML
SUBJECT_SAMPLE_FACTORS           	428	R3_G5_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_G5_5.mzML
SUBJECT_SAMPLE_FACTORS           	562	R3_G6_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_G6_4.mzML
SUBJECT_SAMPLE_FACTORS           	3080	R3_G7_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_G7_4.mzML
SUBJECT_SAMPLE_FACTORS           	1454	R3_G8_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_G8_1.mzML
SUBJECT_SAMPLE_FACTORS           	464	R3_G9_3	AT:1 | FDG:3 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_G9_3.mzML
SUBJECT_SAMPLE_FACTORS           	1663	R3_H1_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_H1_2.mzML
SUBJECT_SAMPLE_FACTORS           	4145	R3_H10_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_H10_5.mzML
SUBJECT_SAMPLE_FACTORS           	2717	R3_H11_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_H11_2.mzML
SUBJECT_SAMPLE_FACTORS           	3306	R3_H12_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_H12_4.mzML
SUBJECT_SAMPLE_FACTORS           	1998	R3_H2_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_H2_5.mzML
SUBJECT_SAMPLE_FACTORS           	604	R3_H3_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_H3_5.mzML
SUBJECT_SAMPLE_FACTORS           	199	R3_H4_3	AT:1 | FDG:3 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_H4_3.mzML
SUBJECT_SAMPLE_FACTORS           	2372	R3_H5_4	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_H5_4.mzML
SUBJECT_SAMPLE_FACTORS           	1719	R3_H6_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_H6_5.mzML
SUBJECT_SAMPLE_FACTORS           	820	R3_H7_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_H7_2.mzML
SUBJECT_SAMPLE_FACTORS           	2110	R3_H8_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R3_H8_5.mzML
SUBJECT_SAMPLE_FACTORS           	2384	R4_A1_4	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_A1_4.mzML
SUBJECT_SAMPLE_FACTORS           	346	R4_A10_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_A10_1.mzML
SUBJECT_SAMPLE_FACTORS           	842	R4_A11_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_A11_1.mzML
SUBJECT_SAMPLE_FACTORS           	213	R4_A12_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_A12_1.mzML
SUBJECT_SAMPLE_FACTORS           	2827	R4_A2_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_A2_5.mzML
SUBJECT_SAMPLE_FACTORS           	3130	R4_A3_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_A3_5.mzML
SUBJECT_SAMPLE_FACTORS           	2849	R4_A4_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_A4_2.mzML
SUBJECT_SAMPLE_FACTORS           	3912	R4_A5_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_A5_4.mzML
SUBJECT_SAMPLE_FACTORS           	2577	R4_A6_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_A6_5.mzML
SUBJECT_SAMPLE_FACTORS           	3259	R4_A7_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_A7_4.mzML
SUBJECT_SAMPLE_FACTORS           	2230	R4_A8_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_A8_4.mzML
SUBJECT_SAMPLE_FACTORS           	57	R4_A9_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_A9_1.mzML
SUBJECT_SAMPLE_FACTORS           	2156	R4_B1_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_B1_5.mzML
SUBJECT_SAMPLE_FACTORS           	1357	R4_B10_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_B10_1.mzML
SUBJECT_SAMPLE_FACTORS           	880	R4_B11_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_B11_1.mzML
SUBJECT_SAMPLE_FACTORS           	2566	R4_B2_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_B2_4.mzML
SUBJECT_SAMPLE_FACTORS           	1526	R4_B4_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_B4_5.mzML
SUBJECT_SAMPLE_FACTORS           	1477	R4_B5_3	AT:1 | FDG:3 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_B5_3.mzML
SUBJECT_SAMPLE_FACTORS           	1962	R4_B7_3	AT:1 | FDG:3 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_B7_3.mzML
SUBJECT_SAMPLE_FACTORS           	2660	R4_B8_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_B8_2.mzML
SUBJECT_SAMPLE_FACTORS           	171	R4_B9_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_B9_1.mzML
SUBJECT_SAMPLE_FACTORS           	2639	R4_C1_3	AT:1 | FDG:3 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_C1_3.mzML
SUBJECT_SAMPLE_FACTORS           	542	R4_C10_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_C10_1.mzML
SUBJECT_SAMPLE_FACTORS           	1323	R4_C11_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_C11_1.mzML
SUBJECT_SAMPLE_FACTORS           	364	R4_C12_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_C12_1.mzML
SUBJECT_SAMPLE_FACTORS           	1514	R4_C2_3	AT:1 | FDG:3 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_C2_3.mzML
SUBJECT_SAMPLE_FACTORS           	843	R4_C3_2	AT:1 | FDG:3 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_C3_2.mzML
SUBJECT_SAMPLE_FACTORS           	1769	R4_C4_3	AT:1 | FDG:3 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_C4_3.mzML
SUBJECT_SAMPLE_FACTORS           	2807	R4_C5_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_C5_4.mzML
SUBJECT_SAMPLE_FACTORS           	3319	R4_C6_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_C6_4.mzML
SUBJECT_SAMPLE_FACTORS           	111	R4_C7_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_C7_5.mzML
SUBJECT_SAMPLE_FACTORS           	956	R4_C8_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_C8_1.mzML
SUBJECT_SAMPLE_FACTORS           	114	R4_C9_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_C9_1.mzML
SUBJECT_SAMPLE_FACTORS           	2174	R4_D1_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_D1_4.mzML
SUBJECT_SAMPLE_FACTORS           	584	R4_D10_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_D10_1.mzML
SUBJECT_SAMPLE_FACTORS           	291	R4_D11_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_D11_1.mzML
SUBJECT_SAMPLE_FACTORS           	191	R4_D12_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_D12_1.mzML
SUBJECT_SAMPLE_FACTORS           	1611	R4_D2_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_D2_4.mzML
SUBJECT_SAMPLE_FACTORS           	2609	R4_D3_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_D3_4.mzML
SUBJECT_SAMPLE_FACTORS           	2299	R4_D4_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_D4_5.mzML
SUBJECT_SAMPLE_FACTORS           	1390	R4_D5_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_D5_5.mzML
SUBJECT_SAMPLE_FACTORS           	3649	R4_D6_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_D6_5.mzML
SUBJECT_SAMPLE_FACTORS           	2880	R4_D7_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_D7_4.mzML
SUBJECT_SAMPLE_FACTORS           	894	R4_D8_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_D8_1.mzML
SUBJECT_SAMPLE_FACTORS           	1021	R4_D9_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_D9_1.mzML
SUBJECT_SAMPLE_FACTORS           	2263	R4_E1_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_E1_2.mzML
SUBJECT_SAMPLE_FACTORS           	875	R4_E10_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_E10_1.mzML
SUBJECT_SAMPLE_FACTORS           	353	R4_E11_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_E11_1.mzML
SUBJECT_SAMPLE_FACTORS           	1169	R4_E12_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_E12_1.mzML
SUBJECT_SAMPLE_FACTORS           	1030	R4_E2_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_E2_2.mzML
SUBJECT_SAMPLE_FACTORS           	2504	R4_E3_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_E3_5.mzML
SUBJECT_SAMPLE_FACTORS           	1889	R4_E7_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_E7_2.mzML
SUBJECT_SAMPLE_FACTORS           	68	R4_E8_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_E8_1.mzML
SUBJECT_SAMPLE_FACTORS           	844	R4_E9_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_E9_1.mzML
SUBJECT_SAMPLE_FACTORS           	3154	R4_F1_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_F1_4.mzML
SUBJECT_SAMPLE_FACTORS           	498	R4_F10_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_F10_1.mzML
SUBJECT_SAMPLE_FACTORS           	1184	R4_F11_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_F11_1.mzML
SUBJECT_SAMPLE_FACTORS           	431	R4_F12_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_F12_1.mzML
SUBJECT_SAMPLE_FACTORS           	1965	R4_F2_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_F2_2.mzML
SUBJECT_SAMPLE_FACTORS           	2029	R4_F3_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_F3_1.mzML
SUBJECT_SAMPLE_FACTORS           	665	R4_F5_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_F5_2.mzML
SUBJECT_SAMPLE_FACTORS           	1755	R4_F6_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_F6_4.mzML
SUBJECT_SAMPLE_FACTORS           	459	R4_F8_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_F8_1.mzML
SUBJECT_SAMPLE_FACTORS           	911	R4_F9_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_F9_1.mzML
SUBJECT_SAMPLE_FACTORS           	1330	R4_G1_4	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_G1_4.mzML
SUBJECT_SAMPLE_FACTORS           	808	R4_G10_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_G10_1.mzML
SUBJECT_SAMPLE_FACTORS           	104	R4_G11_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_G11_1.mzML
SUBJECT_SAMPLE_FACTORS           	208	R4_G12_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_G12_1.mzML
SUBJECT_SAMPLE_FACTORS           	3075	R4_G3_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_G3_5.mzML
SUBJECT_SAMPLE_FACTORS           	1821	R4_G5_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_G5_5.mzML
SUBJECT_SAMPLE_FACTORS           	2002	R4_G7_2	AT:1 | FDG:3 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_G7_2.mzML
SUBJECT_SAMPLE_FACTORS           	774	R4_G8_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_G8_1.mzML
SUBJECT_SAMPLE_FACTORS           	981	R4_G9_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_G9_1.mzML
SUBJECT_SAMPLE_FACTORS           	97	R4_H1_5	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_H1_5.mzML
SUBJECT_SAMPLE_FACTORS           	865	R4_H10_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_H10_1.mzML
SUBJECT_SAMPLE_FACTORS           	1162	R4_H11_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_H11_1.mzML
SUBJECT_SAMPLE_FACTORS           	169	R4_H12_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_H12_1.mzML
SUBJECT_SAMPLE_FACTORS           	2668	R4_H2_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_H2_2.mzML
SUBJECT_SAMPLE_FACTORS           	317	R4_H3_3	AT:1 | FDG:3 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_H3_3.mzML
SUBJECT_SAMPLE_FACTORS           	1239	R4_H4_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_H4_2.mzML
SUBJECT_SAMPLE_FACTORS           	941	R4_H5_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_H5_2.mzML
SUBJECT_SAMPLE_FACTORS           	3087	R4_H6_5	AT:1 | FDG:4 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_H6_5.mzML
SUBJECT_SAMPLE_FACTORS           	3013	R4_H7_4	AT:1 | FDG:5 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_H7_4.mzML
SUBJECT_SAMPLE_FACTORS           	410	R4_H8_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_H8_1.mzML
SUBJECT_SAMPLE_FACTORS           	718	R4_H9_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R4_H9_1.mzML
SUBJECT_SAMPLE_FACTORS           	1212	R5_A1_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R5_A1_1.mzML
SUBJECT_SAMPLE_FACTORS           	228	R5_A2_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R5_A2_1.mzML
SUBJECT_SAMPLE_FACTORS           	4099	R5_A3_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R5_A3_1.mzML
SUBJECT_SAMPLE_FACTORS           	1339	R5_B1_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R5_B1_1.mzML
SUBJECT_SAMPLE_FACTORS           	812	R5_B2_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R5_B2_1.mzML
SUBJECT_SAMPLE_FACTORS           	969	R5_C1_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R5_C1_1.mzML
SUBJECT_SAMPLE_FACTORS           	1085	R5_C2_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R5_C2_1.mzML
SUBJECT_SAMPLE_FACTORS           	1269	R5_D1_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R5_D1_1.mzML
SUBJECT_SAMPLE_FACTORS           	603	R5_D2_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R5_D2_1.mzML
SUBJECT_SAMPLE_FACTORS           	1019	R5_E1_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R5_E1_1.mzML
SUBJECT_SAMPLE_FACTORS           	501	R5_E2_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R5_E2_1.mzML
SUBJECT_SAMPLE_FACTORS           	1264	R5_F1_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R5_F1_1.mzML
SUBJECT_SAMPLE_FACTORS           	2084	R5_F2_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R5_F2_1.mzML
SUBJECT_SAMPLE_FACTORS           	1302	R5_G1_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R5_G1_1.mzML
SUBJECT_SAMPLE_FACTORS           	1429	R5_G2_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R5_G2_1.mzML
SUBJECT_SAMPLE_FACTORS           	225	R5_H1_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R5_H1_1.mzML
SUBJECT_SAMPLE_FACTORS           	2893	R5_H2_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R5_H2_1.mzML
SUBJECT_SAMPLE_FACTORS           	3397	R6_A1_2	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R6_A1_2.mzML
SUBJECT_SAMPLE_FACTORS           	2383	R6_B1_3	AT:1 | FDG:3 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R6_B1_3.mzML
SUBJECT_SAMPLE_FACTORS           	2479	R7_A2_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R7_A2_1.mzML
SUBJECT_SAMPLE_FACTORS           	4236	R7_A3_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R7_A3_1.mzML
SUBJECT_SAMPLE_FACTORS           	2467	R7_A4_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R7_A4_1.mzML
SUBJECT_SAMPLE_FACTORS           	1807	R7_A5_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R7_A5_1.mzML
SUBJECT_SAMPLE_FACTORS           	1516	R7_B1_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R7_B1_1.mzML
SUBJECT_SAMPLE_FACTORS           	633	R7_B2_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R7_B2_1.mzML
SUBJECT_SAMPLE_FACTORS           	2874	R7_B3_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R7_B3_1.mzML
SUBJECT_SAMPLE_FACTORS           	962	R7_B4_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R7_B4_1.mzML
SUBJECT_SAMPLE_FACTORS           	2854	R7_B5_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R7_B5_1.mzML
SUBJECT_SAMPLE_FACTORS           	1860	R7_C1_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R7_C1_1.mzML
SUBJECT_SAMPLE_FACTORS           	1216	R7_C2_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R7_C2_1.mzML
SUBJECT_SAMPLE_FACTORS           	946	R7_C3_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R7_C3_1.mzML
SUBJECT_SAMPLE_FACTORS           	3091	R7_C4_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R7_C4_1.mzML
SUBJECT_SAMPLE_FACTORS           	3713	R7_C5_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R7_C5_1.mzML
SUBJECT_SAMPLE_FACTORS           	1439	R7_D1_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R7_D1_1.mzML
SUBJECT_SAMPLE_FACTORS           	3673	R7_D2_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R7_D2_1.mzML
SUBJECT_SAMPLE_FACTORS           	1447	R7_D3_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R7_D3_1.mzML
SUBJECT_SAMPLE_FACTORS           	4196	R7_D4_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R7_D4_1.mzML
SUBJECT_SAMPLE_FACTORS           	3088	R7_D5_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R7_D5_1.mzML
SUBJECT_SAMPLE_FACTORS           	1405	R7_E1_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R7_E1_1.mzML
SUBJECT_SAMPLE_FACTORS           	3964	R7_E2_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R7_E2_1.mzML
SUBJECT_SAMPLE_FACTORS           	2490	R7_E3_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R7_E3_1.mzML
SUBJECT_SAMPLE_FACTORS           	2970	R7_E4_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R7_E4_1.mzML
SUBJECT_SAMPLE_FACTORS           	4121	R7_E5_1	AT:1 | FDG:2 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R7_E5_1.mzML
SUBJECT_SAMPLE_FACTORS           	1253	R7_F1_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R7_F1_1.mzML
SUBJECT_SAMPLE_FACTORS           	533	R7_F2_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R7_F2_1.mzML
SUBJECT_SAMPLE_FACTORS           	1703	R7_F3_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R7_F3_1.mzML
SUBJECT_SAMPLE_FACTORS           	3799	R7_G2_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R7_G2_1.mzML
SUBJECT_SAMPLE_FACTORS           	481	R7_G3_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R7_G3_1.mzML
SUBJECT_SAMPLE_FACTORS           	3869	R7_G4_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R7_G4_1.mzML
SUBJECT_SAMPLE_FACTORS           	359	R7_H1_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R7_H1_1.mzML
SUBJECT_SAMPLE_FACTORS           	690	R7_H2_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R7_H2_1.mzML
SUBJECT_SAMPLE_FACTORS           	3982	R7_H3_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R7_H3_1.mzML
SUBJECT_SAMPLE_FACTORS           	876	R7_H4_1	AT:0 | FDG:1 | Sample source:plasma	RAW_FILE_NAME(mzML file name)=R7_H4_1.mzML
#COLLECTION
CO:COLLECTION_SUMMARY            	This study was conducted in a subset of participants (n=400) from the PESA study
CO:COLLECTION_SUMMARY            	(Progression of Early Subclinical Atherosclerosis) (PMID: 34238438). The
CO:COLLECTION_SUMMARY            	PESA-CNIC-Santander (NCT01410318) is an ongoing observational prospective cohort
CO:COLLECTION_SUMMARY            	study of 4,184 asymptomatic employees of the Santander Bank in Madrid (subjects
CO:COLLECTION_SUMMARY            	from 40 to 54 years of age and free of known CVD at baseline in 2009). In
CO:COLLECTION_SUMMARY            	addition to the exclusion criteria followed in the main study (PMID: 25882487),
CO:COLLECTION_SUMMARY            	subjects taking antibiotics in the three months prior to the sample collection,
CO:COLLECTION_SUMMARY            	with known Type 2 diabetes or treated for diabetes and/or intestinal disorders
CO:COLLECTION_SUMMARY            	were excluded from our study. This allowed removing possible confounding effects
CO:COLLECTION_SUMMARY            	due to the role of ImP in diabetes and insulin resistance (PMID: 30401435) and
CO:COLLECTION_SUMMARY            	to the modification of gut microbiota possibly affecting the production of ImP.
CO:COLLECTION_SUMMARY            	Subclinical atherosclerosis was assessed by imaging studies including 2D and 3D
CO:COLLECTION_SUMMARY            	vascular ultrasonography of carotid and iliofemoral arteries and presence of
CO:COLLECTION_SUMMARY            	coronary artery calcium assessed by CT scan, as previously described (PMID:
CO:COLLECTION_SUMMARY            	24268213). Subjects with subclinical atherosclerosis underwent a whole body
CO:COLLECTION_SUMMARY            	18F-FDG PET/MRI study to characterize arterial 18F-FDG uptake and bone marrow
CO:COLLECTION_SUMMARY            	metabolic activity, as described (PMID: 30922468 and PMID: 35567559). This
CO:COLLECTION_SUMMARY            	information was used to further stratify subjects with subclinical
CO:COLLECTION_SUMMARY            	atherosclerosis in: inactive atherosclerosis (FDGneg, n=74), arterial 18 F-FDG
CO:COLLECTION_SUMMARY            	uptake (FDG+_A, n=57), bone marrow activation (FDG+_BM, n=40), and both arterial
CO:COLLECTION_SUMMARY            	uptake and bone marrow activation (FDG+_SYS, n=124) as indicatives of
CO:COLLECTION_SUMMARY            	metabolically active atherosclerosis (FDG+, n=221). For the metabolomic
CO:COLLECTION_SUMMARY            	analysis, peripheral blood samples collected after overnight fasting were
CO:COLLECTION_SUMMARY            	centrifuged at 2,750 x g at RT for 10 minutes to obtain plasma that was
CO:COLLECTION_SUMMARY            	further aliquoted and stored at -80°C. The institutional ethics committee
CO:COLLECTION_SUMMARY            	approved the study protocol, and all participants were provided with written
CO:COLLECTION_SUMMARY            	informed consent.
CO:SAMPLE_TYPE                   	Blood (plasma)
#TREATMENT
TR:TREATMENT_SUMMARY             	No therapeutic interventions were applied to participants. The study was
TR:TREATMENT_SUMMARY             	observational.
#SAMPLEPREP
SP:SAMPLEPREP_SUMMARY            	For the PESA cohort, individual 1000PPM stock solutions of ImP (Sigma-Aldrich
SP:SAMPLEPREP_SUMMARY            	77951), urocanic acid (Urocanic acid-1,2,3-13C3, Sigma-Aldrich: 709638) and
SP:SAMPLEPREP_SUMMARY            	histidine (L-Histidine-d3 hydrochloride monohydrate, Sigma-Aldrich:791318) were
SP:SAMPLEPREP_SUMMARY            	prepared in ultrapure water and stored at -20ºC. Their respective dilutions
SP:SAMPLEPREP_SUMMARY            	were then prepared in MeOH/EtOH (1:1, v/v) and stored at 4ºC. For the PESA
SP:SAMPLEPREP_SUMMARY            	cohort, 65 μL of MeOH/EtOH (1:1, v/v) were added to 50 μL of plasma sample and
SP:SAMPLEPREP_SUMMARY            	35 μL of isotopic labeled internal standards in MeOH/EtOH (IS) (urocanic acid
SP:SAMPLEPREP_SUMMARY            	and histidine). Samples were vortex-mixed for 10 seconds and then centrifuged at
SP:SAMPLEPREP_SUMMARY            	13,000 rpm for 20 minutes at 4ºC. 100 μL of supernatant were taken and
SP:SAMPLEPREP_SUMMARY            	transferred to LC vials for the analysis
#CHROMATOGRAPHY
CH:CHROMATOGRAPHY_TYPE           	HILIC
CH:INSTRUMENT_NAME               	Agilent 1290 Infinity
CH:COLUMN_NAME                   	InfinityLab Poroshell 120 HILIC-Z column (2.7 μm 150 x 2.1 mm, Agilent
CH:COLUMN_NAME                   	Technologies, Santa Clara, California
CH:SOLVENT_A                     	20 mM ammonium formate in ultrapure water at pH 3
CH:SOLVENT_B                     	20 mM aqueous ammonium formate at pH 3 in ACN/H20 (9:1, v/v)
CH:FLOW_GRADIENT                 	The initial conditions at time 0 were 100 % B, decreasing to 70 % at 11.5 min.
CH:FLOW_GRADIENT                 	The gradient was then increased to 100 % B at time 12.0 min and held until the
CH:FLOW_GRADIENT                 	total run time of 15 min.
CH:FLOW_RATE                     	0.50 mL/min
CH:COLUMN_TEMPERATURE            	25
#ANALYSIS
AN:ANALYSIS_TYPE                 	MS
#MS
MS:INSTRUMENT_NAME               	Agilent 6460 QQQ
MS:INSTRUMENT_TYPE               	Triple quadrupole
MS:MS_TYPE                       	ESI
MS:ION_MODE                      	POSITIVE
MS:MS_COMMENTS                   	Raw signals for multiple reaction monitoring (MRM) transitions were checked and
MS:MS_COMMENTS                   	peaks corresponding to all the targeted compounds were integrated by MassHunter
MS:MS_COMMENTS                   	Quantitative B.10.00 (Agilent Technologies). Multiple reaction monitoring
MS:MS_COMMENTS                   	transitions (collision energy, eV) were as follows: 141 > 123 (10) and 141 > 81
MS:MS_COMMENTS                   	(26) for ImP; 139 > 121 (10) and 139 > 93 (26) for urocanic acid; 142 > 124 (10)
MS:MS_COMMENTS                   	and 142 > 41 (26) for labeled urocanic acid; 156 > 110 (10) and 156  > 83
MS:MS_COMMENTS                   	(30), for histidine; and, 159 > 113 (10) and 159 > 86 (30) for labeled
MS:MS_COMMENTS                   	histidine. Quantification of ImP concentration was performed by generating a
MS:MS_COMMENTS                   	standard curve with known concentrations of this metabolite. Histidine and
MS:MS_COMMENTS                   	urocanic acid were instead quantified by using internal standards added to
MS:MS_COMMENTS                   	plasma samples as stated above. Metabolite standards were analysed alongside
MS:MS_COMMENTS                   	plasma samples using the LC-MS/MS method. Dilution of the plasma during sample
MS:MS_COMMENTS                   	preparation was also taken into account for quantification.
#MS_METABOLITE_DATA
MS_METABOLITE_DATA:UNITS	nMol
MS_METABOLITE_DATA_START
Samples	R1_A1_5	R1_A10_2	R1_A11_5	R1_A12_4	R1_A2_2	R1_A3_4	R1_A4_2	R1_A5_5	R1_A6_4	R1_A7_5	R1_A8_5	R1_A9_4	R1_B1_5	R1_B10_3	R1_B11_2	R1_B12_2	R1_B2_1	R1_B3_5	R1_B4_5	R1_B7_3	R1_B8_4	R1_B9_1	R1_C1_1	R1_C10_2	R1_C11_5	R1_C12_5	R1_C2_4	R1_C3_5	R1_C4_5	R1_C5_2	R1_C6_5	R1_C7_4	R1_C8_5	R1_C9_3	R1_D1_5	R1_D10_2	R1_D11_4	R1_D12_3	R1_D3_5	R1_D4_2	R1_D5_1	R1_D6_5	R1_D7_5	R1_D9_2	R1_E1_2	R1_E11_5	R1_E12_2	R1_E2_2	R1_E3_1	R1_E4_5	R1_E5_5	R1_E6_4	R1_E7_2	R1_E8_4	R1_E9_4	R1_F1_5	R1_F10_5	R1_F11_5	R1_F12_2	R1_F2_2	R1_F3_2	R1_F4_2	R1_F5_2	R1_F6_3	R1_F9_5	R1_G1_1	R1_G10_5	R1_G11_5	R1_G2_2	R1_G3_3	R1_G4_5	R1_G5_5	R1_G6_4	R1_G8_5	R1_H10_5	R1_H11_1	R1_H2_2	R1_H3_2	R1_H4_4	R1_H5_1	R1_H6_5	R1_H7_4	R1_H8_4	R1_H9_5	R2_A1_4	R2_A10_4	R2_A11_4	R2_A12_2	R2_A2_2	R2_A3_5	R2_A4_5	R2_A5_2	R2_A6_5	R2_A7_4	R2_A8_2	R2_A9_4	R2_B1_4	R2_B10_2	R2_B11_5	R2_B12_5	R2_B2_5	R2_B3_4	R2_B4_2	R2_B5_2	R2_B6_4	R2_B7_2	R2_B8_3	R2_B9_5	R2_C1_5	R2_C10_5	R2_C11_5	R2_C12_3	R2_C2_2	R2_C3_3	R2_C4_1	R2_C5_2	R2_C6_4	R2_C7_4	R2_C8_2	R2_C9_3	R2_D1_4	R2_D10_2	R2_D11_3	R2_D12_5	R2_D3_4	R2_D4_1	R2_D5_5	R2_D6_5	R2_D8_5	R2_D9_4	R2_E1_5	R2_E10_4	R2_E11_5	R2_E3_3	R2_E4_5	R2_E5_5	R2_E6_5	R2_E7_4	R2_E8_4	R2_E9_5	R2_F1_5	R2_F10_5	R2_F12_4	R2_F2_3	R2_F3_2	R2_F4_2	R2_F5_2	R2_F6_4	R2_F7_2	R2_F8_2	R2_F9_2	R2_G1_5	R2_G10_5	R2_G11_2	R2_G12_5	R2_G2_2	R2_G3_4	R2_G6_2	R2_G7_4	R2_G8_2	R2_G9_2	R2_H1_5	R2_H10_5	R2_H11_4	R2_H12_4	R2_H2_5	R2_H3_4	R2_H4_4	R2_H5_2	R2_H6_5	R2_H7_3	R2_H8_2	R2_H9_3	R3_A1_3	R3_A10_5	R3_A11_3	R3_A12_2	R3_A2_3	R3_A3_5	R3_A4_2	R3_A5_5	R3_A6_2	R3_A7_2	R3_A8_1	R3_A9_2	R3_B1_2	R3_B10_3	R3_B12_5	R3_B2_5	R3_B3_1	R3_B4_2	R3_B5_5	R3_B6_5	R3_B7_3	R3_B8_3	R3_B9_5	R3_C1_4	R3_C10_4	R3_C11_5	R3_C12_5	R3_C2_2	R3_C3_4	R3_C4_4	R3_C5_5	R3_C6_2	R3_C7_5	R3_C8_5	R3_C9_5	R3_D1_2	R3_D10_2	R3_D12_2	R3_D2_1	R3_D3_5	R3_D4_5	R3_D5_3	R3_D6_5	R3_D7_5	R3_D8_4	R3_E1_4	R3_E10_5	R3_E11_4	R3_E12_5	R3_E2_5	R3_E3_2	R3_E4_4	R3_E7_3	R3_E8_2	R3_E9_5	R3_F1_2	R3_F10_1	R3_F11_5	R3_F12_3	R3_F2_1	R3_F3_4	R3_F4_5	R3_F6_5	R3_F7_5	R3_F8_5	R3_F9_1	R3_G1_2	R3_G10_5	R3_G11_4	R3_G12_5	R3_G2_5	R3_G3_2	R3_G4_4	R3_G5_5	R3_G6_4	R3_G7_4	R3_G8_1	R3_G9_3	R3_H1_2	R3_H10_5	R3_H11_2	R3_H12_4	R3_H2_5	R3_H3_5	R3_H4_3	R3_H5_4	R3_H6_5	R3_H7_2	R3_H8_5	R4_A1_4	R4_A10_1	R4_A11_1	R4_A12_1	R4_A2_5	R4_A3_5	R4_A4_2	R4_A5_4	R4_A6_5	R4_A7_4	R4_A8_4	R4_A9_1	R4_B1_5	R4_B10_1	R4_B11_1	R4_B2_4	R4_B4_5	R4_B5_3	R4_B7_3	R4_B8_2	R4_B9_1	R4_C1_3	R4_C10_1	R4_C11_1	R4_C12_1	R4_C2_3	R4_C3_2	R4_C4_3	R4_C5_4	R4_C6_4	R4_C7_5	R4_C8_1	R4_C9_1	R4_D1_4	R4_D10_1	R4_D11_1	R4_D12_1	R4_D2_4	R4_D3_4	R4_D4_5	R4_D5_5	R4_D6_5	R4_D7_4	R4_D8_1	R4_D9_1	R4_E1_2	R4_E10_1	R4_E11_1	R4_E12_1	R4_E2_2	R4_E3_5	R4_E7_2	R4_E8_1	R4_E9_1	R4_F1_4	R4_F10_1	R4_F11_1	R4_F12_1	R4_F2_2	R4_F3_1	R4_F5_2	R4_F6_4	R4_F8_1	R4_F9_1	R4_G1_4	R4_G10_1	R4_G11_1	R4_G12_1	R4_G3_5	R4_G5_5	R4_G7_2	R4_G8_1	R4_G9_1	R4_H1_5	R4_H10_1	R4_H11_1	R4_H12_1	R4_H2_2	R4_H3_3	R4_H4_2	R4_H5_2	R4_H6_5	R4_H7_4	R4_H8_1	R4_H9_1	R5_A1_1	R5_A2_1	R5_A3_1	R5_B1_1	R5_B2_1	R5_C1_1	R5_C2_1	R5_D1_1	R5_D2_1	R5_E1_1	R5_E2_1	R5_F1_1	R5_F2_1	R5_G1_1	R5_G2_1	R5_H1_1	R5_H2_1	R6_A1_2	R6_B1_3	R7_A2_1	R7_A3_1	R7_A4_1	R7_A5_1	R7_B1_1	R7_B2_1	R7_B3_1	R7_B4_1	R7_B5_1	R7_C1_1	R7_C2_1	R7_C3_1	R7_C4_1	R7_C5_1	R7_D1_1	R7_D2_1	R7_D3_1	R7_D4_1	R7_D5_1	R7_E1_1	R7_E2_1	R7_E3_1	R7_E4_1	R7_E5_1	R7_F1_1	R7_F2_1	R7_F3_1	R7_G2_1	R7_G3_1	R7_G4_1	R7_H1_1	R7_H2_1	R7_H3_1	R7_H4_1
Factors	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:3 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:3 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:3 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:3 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:3 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:3 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:3 | Sample source:plasma	AT:1 | FDG:3 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:3 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:3 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:3 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:3 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:3 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:3 | Sample source:plasma	AT:1 | FDG:3 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:3 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:3 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:3 | Sample source:plasma	AT:1 | FDG:3 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:3 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:3 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:3 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:3 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:3 | Sample source:plasma	AT:1 | FDG:3 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:3 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:3 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:3 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:1 | FDG:3 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:1 | FDG:3 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:3 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:3 | Sample source:plasma	AT:1 | FDG:3 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:1 | FDG:3 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:1 | FDG:3 | Sample source:plasma	AT:1 | FDG:3 | Sample source:plasma	AT:1 | FDG:3 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:1 | FDG:3 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:3 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:4 | Sample source:plasma	AT:1 | FDG:5 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:1 | FDG:3 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:1 | FDG:2 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma	AT:0 | FDG:1 | Sample source:plasma
Urocanic acid	10.00942854	16.19318134	16.45790466	6.02359081	5.563359886	10.91183627	9.316712268	7.257815067	7.648402892	16.05967211	5.354659673	2.923035884	17.03122675	4.59747659	12.33149739	10.55097892	9.708760356	3.887524921	7.381903164	2.404871593	9.506150284	5.220128371	18.03658599	12.28416768	14.44802043	5.406198197	9.961698576	3.714273624	5.390451493	11.84068455	10.98036003	3.57997656	20.71597408	12.01323758	13.99701093	11.22667057	24.57259179	7.461276892	12.33893496	22.75381981	9.929613947	11.56642997	5.332732778	1.614947566	25.5719011	4.799921997	10.21715969	19.15080062	19.3791981	15.3141496	10.16037423	3.765304193	9.054381689	16.48557989	9.090717934	11.90398051	12.87794693	10.11321461	3.434393914	12.81734586	9.526935928	5.650851388	19.54652373	19.34896524	10.61555083	7.069250246	7.77275766	3.625100833	8.609920953	5.828577059	13.00066212	5.965589118	7.465442909	8.590081904	8.383260136	15.65787617	2.172113039	10.28904804	15.5023085	7.753333323	23.00811955	14.84502913	39.55364512	14.10512924	23.88357583	12.49036126	5.787072748	20.98144765	14.40647827	10.78154686	7.105509135	18.22706585	16.99226869	7.057434342	7.723650571	5.98317688	7.284929845	11.86575275	4.517126648	10.9822025	10.26147065	6.727584361	9.884704969	4.81937964	16.57682565	9.327156311	14.1751661	15.37031768	10.02386955	8.714822739	20.24584909	10.76870396	6.422128739	9.212195195	5.287484646	21.76629692	6.964207754	29.46392806	13.00873127	8.958530888	9.216233572	32.53925398	26.94815748	17.58261074	11.32174972	10.02681132	11.52703992	10.16885314	30.12570873	8.760535864	8.522078772	4.692696139	7.883564328	10.94668559	6.557704816	18.88154475	12.26430214	7.421923395	3.573097355	7.547242548	8.645791781	15.05825672	8.361534708	3.909144097	8.872019319	8.566398699	37.71608622	16.04520928	14.7979146	1.7245407	4.649672095	8.060216563	10.51247468	3.123870446	18.97918505	7.304154407	11.53356599	13.93470973	21.46482241	12.04401011	12.11905988	3.296001347	28.33588331	22.31762705	9.600446264	13.65565458	7.619421261	8.724605067	5.579812822	5.630311339	19.95435965	6.511937649	11.6373803	9.025135437	7.972083728	8.563992549	6.167957163	7.203677465	4.593133132	7.987278767	13.94152153	23.66692082	12.05562207	8.738082064	12.27908311	12.38421525	9.396608494	3.7047954	10.88106125	11.03532826	7.413105364	10.44230752	3.538515878	13.13372177	2.702375791	5.869502563	3.607389945	12.17235936	17.98565524	14.45711824	13.42094114	15.46718959	7.542007786	14.34036824	4.536861211	21.80326479	7.906780737	5.191183994	13.84698883	18.52187975	7.100495344	25.54840098	8.78728123	10.69976233	9.677781078	5.518861188	12.01300566	13.82614889	12.7606629	12.38102396	9.452938873	39.85535693	14.36134088	5.298239257	10.80162959	15.3500431	6.223254342	2.868293405	43.21013209	12.92996122	9.177449525	12.35490999	8.76552963	15.78601168	24.09773198	8.097942992	7.982331247	9.148551549	6.143757568	11.44778576	4.551030503	25.44172557	8.216306231	2.18589178	5.309786583	10.28704839	21.48859619	6.915728986	9.153872696	21.35344628	3.508371949	20.0209233	9.250879021	4.428993556	7.521916477	1.473649322	9.986112163	26.40269863	7.6455785	4.55264895	3.326826972	38.97270307	9.073397427	13.90023413	7.170145531	16.28216707	9.782560846	12.3664749	9.511040983	10.00491456	20.64901419	13.86578013	9.774736711	7.533500485	3.733853063	18.88118685	10.40676338	11.02019603	11.92569327	13.27336374	36.40519429	9.929133756	3.57415677	19.27006257	4.328750386	22.94920764	8.403102236	11.97507132	23.30737058	17.94200539	10.33051216	12.13176583	10.49120237	21.24426917	10.60187658	9.387184697	3.625709132	10.07732442	22.89286984	2.845334036	6.269295153	4.051031381	9.836127194	22.53427924	13.57405428	18.91642777	9.704816916	7.116216889	6.996377093	9.895174039	3.151699892	4.134798188	16.32948023	14.43500206	28.17895625	15.84802819	9.618832628	10.88706112	6.691396312	9.019161854	7.809659628	9.631246892	8.940711709	11.13155393	11.687897	14.12328646	19.50660809	10.03525438	7.407609497	20.64067705	13.64974312	10.82125053	2.653256304	10.23742115	7.217899124	10.97617629	10.37057136	27.65840182	9.4059394	11.56207091	13.55041444	4.142551859	63.43482998	4.592045012	3.578180643	17.64950101	14.55482242	9.797378736	11.55666235	3.151567227	11.73827953	7.191943741	3.761450373	11.87264668	33.65614961	6.353164041	7.216085395	7.655273878	21.79481562	5.072912867	4.554836461	12.99908514	20.68763388	3.860369545	8.789303867	7.529271275	9.220227013	10.22524873	6.80198018	13.84275379	14.60603849	16.30896567	23.1937499	12.85393831	8.545932425	3.879240671	8.961831664	11.83242379	20.87979729	8.508805344	13.16633739	13.47017344	13.91797823	9.906393566	7.16079583	18.7605572	6.316418433	11.90399792	4.968632797	1.451306365	13.64669178	13.43409222	12.44458515	6.806545568	7.816583036	3.782694504	10.94199065	11.28530459	9.870148491	6.926035834
Imidazole propionate	29.47	23.42	32.11	14.65	24.41	52.65	35.04	95.05	99.6	3.5	57.34	17.71	21.72	24.87	11.34	12.78	16.93	53.41	29.11	91.14	34.11	22.78	35.43	9.05	18.44	129.21	30.36	42.35	97.78	19.81	31.36	24.49	86.15	50.02	31.74	39.44	73.65	43.71	24.81	17.62	13.66	19.57	15.15	42	26.65	23.99	26	31.69	33.39	12.96	27.56	44.19	31.09	25.64	233.32	25.7	45.13	35.71	21.42	15.53	52.1	12.69	29.5	31.28	47.29	23.68	28.42	32.34	4.34	27.94	50.45	19.73	34.54	23.73	24.71	15.81	59.02	19.51	37.37	27.88	90.7	22.86	13.34	33.47	41.22	33.39	26.66	26.81	26.2	29.39	24.96	19.86	53.75	30.49	19.98	23.19	26.92	51.13	28.95	52.8	29.13	18.55	26.12	14.98	60.72	13.35	27	42.96	32.76	22.3	39.03	13.23	23.35	26.02	25.87	25.1	27.31	28.5	42.17	21.38	17.53	29.62	47.63	32.81	21.56	30.54	22.41	51.12	40.54	27.94	50.5	14.96	13.27	30.15	18.73	36.6	20.67	18.87	47.28	26.86	25.75	20.95	9.32	39.03	37.6	19.47	11.79	37.78	9.99	57.36	54.48	30.97	22.26	42.04	28.14	14.89	34.72	23.08	21.54	28.07	20.6	26.49	47.76	22.29	89.89	28.67	10.52	56.13	43.89	34.95	27.92	18.56	61.05	17.8	29.16	1.26	102.48	44.12	81.24	26.66	19.46	173.65	22.02	36.24	11.1	29.5	33.35	17.76	17.38	11.4	63.72	19.18	69.79	55.17	41.46	85.39	23.08	32.94	26.77	29.5	9.19	44.83	3.36	56.38	19.68	37.15	15.7	47.38	28.6	123.46	23.84	26.33	33.77	52.65	23.94	16.06	58.41	89.29	14.73	12.66	33.21	15.11	12.1	43.35	14.22	29.98	30.75	25.42	19.02	27.7	54.1	44.06	20.03	28.27	63.24	11.91	66.38	40.79	21.95	22.98	39.99	20.7	16.98	266.02	19.77	52.2	22.63	15.98	15.06	19.08	33.47	23.72	11.63	26.56	14.69	24.41	59.05	33.84	11.37	45.21	26.1	10.17	30.83	10.82	33.33	1.53	23	42.18	11.8	47.28	113.07	39.72	40.59	24.5	47.09	28.2	34.85	42.46	62.37	28.47	24.08	43.66	34.81	39.34	19.91	25.06	16.43	35.64	58.57	39.97	14.96	29.94	25.87	11.5	17.26	46.5	21.52	23.17	13.52	16.01	22.83	42.97	23.1	120.83	31.45	18.15	29.11	20.07	17.7	20.42	34.47	23.75	42.73	31.62	40.99	2.94	39.75	12.76	26.44	58.06	21.84	12.32	32.42	88.35	59.5	35.81	29.81	34.13	14.23	20.69	12.6	21.85	57.91	19.62	29.25	24.73	34.95	15.47	21.45	11.72	77.08	20.19	57.62	19.73	29.89	57.16	55.34	35.45	30.96	63.62	22.53	28.4	12.02	26.04	18.52	44.82	42.79	33.72	13.28	27.72	23.9	20.91	6.91	33.99	55.17	10.79	44.15	19.36	48.72	27.82	40.52	7.6	12.12	23.91	13.35	36.65	55.98	30.36	27.37	32.31	20.89	12.06	53.31	30.96	23.42	50.32	47.42	50.08	32.8	57.02	30.05	49.12	11.58	31.03	25.19	41.58	21.03	9.6	37.01	11.64
Histidine	71840	97310	73810	72290	86200	90140	104480	64920	79160	64770	92340	78880	116070	84730	70070	71600	71100	83090	113680	86230	66490	67260	72870	85700	71790	87890	75820	86010	109340	92390	97720	79020	56260	67280	80580	95360	73240	77470	97760	69370	76550	79370	83400	75950	66880	73440	65420	87370	74700	64760	80350	86110	86270	83660	83360	62390	77930	71930	69280	58130	92370	84390	91020	88980	77140	69120	70390	96090	70760	79670	61960	75420	88890	82410	74330	93900	84590	72790	72290	70360	79050	90230	74350	63610	78910	80850	73860	71960	74910	104840	70240	85880	58970	66220	92390	70960	71850	76980	81480	83560	85370	75660	70060	73650	62920	65200	75650	77720	72540	82780	74270	74680	75070	106130	77500	90400	69700	106470	82280	66120	71720	76810	85260	70950	79250	84220	77530	87770	75410	88980	80800	78480	74930	85360	80240	82290	74620	81510	85060	85410	77320	80690	72090	66240	81980	75700	61730	85230	74310	78460	66370	83360	117420	73030	76890	80310	75830	67060	85670	71540	91640	66480	88650	81180	73360	77970	74950	80900	69900	88310	62110	87110	82410	81760	64530	98620	87570	76940	72260	72180	78690	69980	92880	80080	78150	84840	70810	93050	71310	86950	97020	72180	80810	76190	67490	67910	100860	73840	76660	77310	79060	63420	72480	63710	80760	88240	81690	63760	83130	77510	68440	73680	81190	73770	86250	66680	82640	70400	66030	87050	102950	75490	71500	84320	76720	73530	75030	79140	88800	67190	69340	90540	78550	101610	83280	83850	57960	66520	84790	73910	68910	83330	75120	107260	70800	85780	65450	99420	103300	77690	83900	73220	94780	84960	98040	77220	85570	92980	73230	98460	82460	74150	69760	84620	79970	78030	73640	70280	84620	89940	80900	99400	101770	79720	83950	83850	72950	71530	64560	66660	79060	84540	72770	105890	71850	71730	72330	83280	80600	103370	75920	74890	73180	84990	79660	81480	74420	84770	75940	81600	79160	90210	65060	71150	85530	109880	78630	70430	76440	94850	73650	75790	73260	85050	68530	86240	70880	92200	71140	88570	85970	78140	79730	74110	84340	79270	93760	81500	82080	69350	76310	81250	77740	69680	93910	73310	84300	91760	74130	63430	77350	70700	81100	85050	89390	75120	81840	83050	69430	72820	75860	83680	87100	75570	73690	85300	58960	80840	86500	78930	73370	82460	72500	82420	82920	82460	84850	72010	76950	78020	65090	81450	80770	83140	105120	79330	67450	70610	79670	86320	83630	51070	81730	102110	82210	72930	69700	86000	67900	80600	79510	88280	72050	78700	84840	63430	108690	87920	85770	101800
MS_METABOLITE_DATA_END
#METABOLITES
METABOLITES_START
metabolite_name	retention index	quantified m/z	PubChem ID	KEGG ID
Urocanic acid	4.43	139.05	736715	C00785                      
Imidazole propionate	7.42	141.0656	70630	C20522                      
Histidine	12.89	154.06	6274	C00135
METABOLITES_END
#END