#METABOLOMICS WORKBENCH Jung_DNLI_20250623_151403 DATATRACK_ID:6083 STUDY_ID:ST004058 ANALYSIS_ID:AN006710 PROJECT_ID:PR002548
VERSION             	1
CREATED_ON             	July 22, 2025, 11:13 am
#PROJECT
PR:PROJECT_TITLE                 	Lysosomal polyamine storage upon ATP13A2 loss impairs β-glucocerebrosidase via
PR:PROJECT_TITLE                 	altered lysosomal pH and electrostatic hydrolase-lipid interactions
PR:PROJECT_TYPE                  	Preclinical Mouse and cellular studies
PR:PROJECT_SUMMARY               	ATP13A2 is an endolysosomal polyamine transporter mutated in several
PR:PROJECT_SUMMARY               	neurodegenerative conditions involving lysosomal defects, including
PR:PROJECT_SUMMARY               	Parkinson’s disease (PD). While polyamines are polybasic and polycationic
PR:PROJECT_SUMMARY               	molecules that play pleiotropic cellular roles, their specific impact on
PR:PROJECT_SUMMARY               	lysosomal health is unknown. Here, we demonstrate lysosomal polyamine
PR:PROJECT_SUMMARY               	accumulation in ATP13A2 knockout (KO) cell lines. Primary polyamine storage
PR:PROJECT_SUMMARY               	caused secondary storage of lysosomal anionic phospholipid
PR:PROJECT_SUMMARY               	bis(monoacylglycero)phosphate (BMP) and age-dependent increase in the
PR:PROJECT_SUMMARY               	β-glucocerebrosidase (GCase) substrate, glucosylsphingosine, in Atp13a2 KO
PR:PROJECT_SUMMARY               	brains. Polyamine accumulation inhibited lysosomal GCase activity in cells and
PR:PROJECT_SUMMARY               	this was reversed by lysosome reacidification or BMP supplementation. A
PR:PROJECT_SUMMARY               	liposome-based GCase assay utilizing physiological substrates demonstrated
PR:PROJECT_SUMMARY               	dose-dependent inhibition of BMP-stimulated GCase activity by polyamines, in
PR:PROJECT_SUMMARY               	part via a pH-independent, electrostatics-based mechanism. Therefore, excess
PR:PROJECT_SUMMARY               	polyamine compromises lysosomes by disrupting pH and electrostatic interactions
PR:PROJECT_SUMMARY               	between GCase and BMP enabling efficient substrate hydrolysis, potentially
PR:PROJECT_SUMMARY               	clarifying their pathogenic mechanisms, and suggesting convergence on
PR:PROJECT_SUMMARY               	PD-relevant pathways.
PR:INSTITUTE                     	Denali Therapeutics
PR:LAST_NAME                     	Suh
PR:FIRST_NAME                    	Jung
PR:ADDRESS                       	161 Oyster Point Blvd, South San Francisco, California, 94080, USA
PR:EMAIL                         	suh@dnli.com
PR:PHONE                         	+1 6507973837
#STUDY
ST:STUDY_TITLE                   	Targeted Lipid and Metabolite Profiling in ATP13A2 knockout (KO) in HAP1 cells
ST:STUDY_SUMMARY                 	Targeted profiling of lipids and metabolites was performed in ATP13A2 knockout
ST:STUDY_SUMMARY                 	(KO) HAP1 cells with and without polyamine (Spermine) and lipid (DOPC or PG
ST:STUDY_SUMMARY                 	22:6) treatments.
ST:INSTITUTE                     	Denali Therapeutics
ST:LAST_NAME                     	Suh
ST:FIRST_NAME                    	Jung
ST:ADDRESS                       	161 Oyster Point Blvd
ST:EMAIL                         	suh@dnli.com
ST:PHONE                         	+1 6507973837
#SUBJECT
SU:SUBJECT_TYPE                  	Cultured cells
SU:SUBJECT_SPECIES               	Homo sapiens
SU:TAXONOMY_ID                   	9606
#SUBJECT_SAMPLE_FACTORS:         	SUBJECT(optional)[tab]SAMPLE[tab]FACTORS(NAME:VALUE pairs separated by |)[tab]Raw file names and additional sample data
SUBJECT_SAMPLE_FACTORS           	Pool_001	HSA-000043722	Genotype:NA | Treatment:NA | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=-; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000956_HALO_Pos_002.mzML
SUBJECT_SAMPLE_FACTORS           	KO_b	HSA-000043633	Genotype:ATP13A2 KO | Treatment:none | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=-; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000956_HALO_Pos_003.mzML
SUBJECT_SAMPLE_FACTORS           	WT_b	HSA-000043625	Genotype:WT | Treatment:none | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=-; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000956_HALO_Pos_007.mzML
SUBJECT_SAMPLE_FACTORS           	WT_a	HSA-000043624	Genotype:WT | Treatment:none | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=-; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000956_HALO_Pos_009.mzML
SUBJECT_SAMPLE_FACTORS           	WT_c	HSA-000043626	Genotype:WT | Treatment:none | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=-; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000956_HALO_Pos_010.mzML
SUBJECT_SAMPLE_FACTORS           	Pool_002	HSA-000043812	Genotype:NA | Treatment:NA | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=-; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000956_HALO_Pos_011.mzML
SUBJECT_SAMPLE_FACTORS           	WT_d	HSA-000043627	Genotype:WT | Treatment:none | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=-; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000956_HALO_Pos_014.mzML
SUBJECT_SAMPLE_FACTORS           	KO_a	HSA-000043632	Genotype:ATP13A2 KO | Treatment:none | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=-; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000956_HALO_Pos_015.mzML
SUBJECT_SAMPLE_FACTORS           	KO_c	HSA-000043634	Genotype:ATP13A2 KO | Treatment:none | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=-; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000956_HALO_Pos_016.mzML
SUBJECT_SAMPLE_FACTORS           	KO_d	HSA-000043635	Genotype:ATP13A2 KO | Treatment:none | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=-; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000956_HALO_Pos_018.mzML
SUBJECT_SAMPLE_FACTORS           	Pool_003	HSA-000043813	Genotype:NA | Treatment:NA | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=-; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000956_HALO_Pos_020.mzML
SUBJECT_SAMPLE_FACTORS           	Pool1_001	HSA-000043814	Genotype:NA | Treatment:NA | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_002.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_002.mzML
SUBJECT_SAMPLE_FACTORS           	pH_KO_c	HSA-000043739	Genotype:ATP13A2 KO | Treatment:PBS | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_003.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_003.mzML
SUBJECT_SAMPLE_FACTORS           	pH_WT_b	HSA-000043726	Genotype:WT | Treatment:PBS | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_004.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_004.mzML
SUBJECT_SAMPLE_FACTORS           	pH_WT_SPM_b	HSA-000043729	Genotype:WT | Treatment:SPM | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_005.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_005.mzML
SUBJECT_SAMPLE_FACTORS           	pH_KO_Rim_a	HSA-000043743	Genotype:ATP13A2 KO | Treatment:Rim | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_006.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_006.mzML
SUBJECT_SAMPLE_FACTORS           	pH_WT_SPM_Rim_c	HSA-000043736	Genotype:WT | Treatment:SPM + Rim | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_007.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_007.mzML
SUBJECT_SAMPLE_FACTORS           	pH_KO_SPM_Rim_b	HSA-000043747	Genotype:ATP13A2 KO | Treatment:SPM + Rim | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_008.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_008.mzML
SUBJECT_SAMPLE_FACTORS           	pH_WT_Rim_a	HSA-000043731	Genotype:WT | Treatment:Rim | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_009.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_009.mzML
SUBJECT_SAMPLE_FACTORS           	pH_WT_Rim_b	HSA-000043732	Genotype:WT | Treatment:Rim | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_010.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_010.mzML
SUBJECT_SAMPLE_FACTORS           	pH_WT_SPM_Rim_b	HSA-000043735	Genotype:WT | Treatment:SPM + Rim | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_011.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_011.mzML
SUBJECT_SAMPLE_FACTORS           	pH_KO_SPM_c	HSA-000043742	Genotype:ATP13A2 KO | Treatment:SPM | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_012.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_012.mzML
SUBJECT_SAMPLE_FACTORS           	pH_KO_SPM_Rim_a	HSA-000043746	Genotype:ATP13A2 KO | Treatment:SPM + Rim | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_013.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_013.mzML
SUBJECT_SAMPLE_FACTORS           	pH_KO_a	HSA-000043737	Genotype:ATP13A2 KO | Treatment:PBS | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_014.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_014.mzML
SUBJECT_SAMPLE_FACTORS           	Pool1_002	HSA-000043815	Genotype:NA | Treatment:NA | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_015.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_015.mzML
SUBJECT_SAMPLE_FACTORS           	pH_WT_Rim_c	HSA-000043733	Genotype:WT | Treatment:Rim | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_016.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_016.mzML
SUBJECT_SAMPLE_FACTORS           	pH_KO_SPM_a	HSA-000043740	Genotype:ATP13A2 KO | Treatment:SPM | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_017.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_017.mzML
SUBJECT_SAMPLE_FACTORS           	pH_WT_SPM_a	HSA-000043728	Genotype:WT | Treatment:SPM | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_018.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_018.mzML
SUBJECT_SAMPLE_FACTORS           	pH_WT_SPM_c	HSA-000043730	Genotype:WT | Treatment:SPM | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_019.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_019.mzML
SUBJECT_SAMPLE_FACTORS           	pH_KO_SPM_Rim_c	HSA-000043748	Genotype:ATP13A2 KO | Treatment:SPM + Rim | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_020.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_020.mzML
SUBJECT_SAMPLE_FACTORS           	pH_KO_Rim_b	HSA-000043744	Genotype:ATP13A2 KO | Treatment:Rim | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_021.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_021.mzML
SUBJECT_SAMPLE_FACTORS           	pH_WT_a	HSA-000043725	Genotype:WT | Treatment:PBS | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_022.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_022.mzML
SUBJECT_SAMPLE_FACTORS           	pH_WT_c	HSA-000043727	Genotype:WT | Treatment:PBS | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_023.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_023.mzML
SUBJECT_SAMPLE_FACTORS           	pH_WT_SPM_Rim_a	HSA-000043734	Genotype:WT | Treatment:SPM + Rim | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_024.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_024.mzML
SUBJECT_SAMPLE_FACTORS           	pH_KO_SPM_b	HSA-000043741	Genotype:ATP13A2 KO | Treatment:SPM | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_025.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_025.mzML
SUBJECT_SAMPLE_FACTORS           	pH_KO_Rim_c	HSA-000043745	Genotype:ATP13A2 KO | Treatment:Rim | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_026.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_026.mzML
SUBJECT_SAMPLE_FACTORS           	pH_KO_b	HSA-000043738	Genotype:ATP13A2 KO | Treatment:PBS | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_027.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_027.mzML
SUBJECT_SAMPLE_FACTORS           	Pool1_003	HSA-000043816	Genotype:NA | Treatment:NA | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_028.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_028.mzML
SUBJECT_SAMPLE_FACTORS           	Pool2_001	HSA-000043817	Genotype:NA | Treatment:NA | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_030.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_030.mzML
SUBJECT_SAMPLE_FACTORS           	PG_WT_c	HSA-000043754	Genotype:WT | Treatment:PBS | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_031.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_031.mzML
SUBJECT_SAMPLE_FACTORS           	PG_WT_SPM_DOPC_b	HSA-000043759	Genotype:WT | Treatment:SPM + DOPC | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_033.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_033.mzML
SUBJECT_SAMPLE_FACTORS           	PG_KO_22 6 PG_b	HSA-000043798	Genotype:ATP13A2 KO | Treatment:22 6 PG | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_034.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_034.mzML
SUBJECT_SAMPLE_FACTORS           	PG_WT_DOPC_c	HSA-000043769	Genotype:WT | Treatment:DOPC | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_035.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_035.mzML
SUBJECT_SAMPLE_FACTORS           	PG_KO_c	HSA-000043778	Genotype:ATP13A2 KO | Treatment:PBS | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_036.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_036.mzML
SUBJECT_SAMPLE_FACTORS           	PG_KO_22 6 PG_a	HSA-000043797	Genotype:ATP13A2 KO | Treatment:22 6 PG | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_037.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_037.mzML
SUBJECT_SAMPLE_FACTORS           	PG_KO_SPM_22 6 PG_b	HSA-000043789	Genotype:ATP13A2 KO | Treatment:SPM + 22 6 PG | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_038.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_038.mzML
SUBJECT_SAMPLE_FACTORS           	PG_WT_SPM_c	HSA-000043757	Genotype:WT | Treatment:SPM | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_039.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_039.mzML
SUBJECT_SAMPLE_FACTORS           	PG_WT_SPM_DOPC_c	HSA-000043760	Genotype:WT | Treatment:SPM + DOPC | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_040.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_040.mzML
SUBJECT_SAMPLE_FACTORS           	PG_KO_a	HSA-000043776	Genotype:ATP13A2 KO | Treatment:PBS | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_041.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_041.mzML
SUBJECT_SAMPLE_FACTORS           	PG_WT_22 6 PG_c	HSA-000043775	Genotype:WT | Treatment:22 6 PG | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_042.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_042.mzML
SUBJECT_SAMPLE_FACTORS           	PG_WT_SPM_a	HSA-000043755	Genotype:WT | Treatment:SPM | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_043.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_043.mzML
SUBJECT_SAMPLE_FACTORS           	PG_WT_b	HSA-000043753	Genotype:WT | Treatment:PBS | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_044.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_044.mzML
SUBJECT_SAMPLE_FACTORS           	PG_KO_22 6 PG_c	HSA-000043799	Genotype:ATP13A2 KO | Treatment:22 6 PG | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_045.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_045.mzML
SUBJECT_SAMPLE_FACTORS           	PG_KO_SPM_DOPC_a	HSA-000043782	Genotype:ATP13A2 KO | Treatment:SPM + DOPC | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_046.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_046.mzML
SUBJECT_SAMPLE_FACTORS           	PG_WT_DOPC_b	HSA-000043768	Genotype:WT | Treatment:DOPC | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_049.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_049.mzML
SUBJECT_SAMPLE_FACTORS           	PG_WT_SPM_22 6 PG_c	HSA-000043766	Genotype:WT | Treatment:SPM + 22 6 PG | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_051.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_051.mzML
SUBJECT_SAMPLE_FACTORS           	PG_WT_SPM_DOPC_a	HSA-000043758	Genotype:WT | Treatment:SPM + DOPC | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_054.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_054.mzML
SUBJECT_SAMPLE_FACTORS           	Pool2_002	HSA-000043818	Genotype:NA | Treatment:NA | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_055.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_055.mzML
SUBJECT_SAMPLE_FACTORS           	PG_WT_SPM_22 6 PG_a	HSA-000043764	Genotype:WT | Treatment:SPM + 22 6 PG | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_057.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_057.mzML
SUBJECT_SAMPLE_FACTORS           	PG_KO_SPM_22 6 PG_c	HSA-000043790	Genotype:ATP13A2 KO | Treatment:SPM + 22 6 PG | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_059.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_059.mzML
SUBJECT_SAMPLE_FACTORS           	PG_KO_SPM_DOPC_c	HSA-000043784	Genotype:ATP13A2 KO | Treatment:SPM + DOPC | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_060.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_060.mzML
SUBJECT_SAMPLE_FACTORS           	PG_KO_DOPC_c	HSA-000043793	Genotype:ATP13A2 KO | Treatment:DOPC | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_062.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_062.mzML
SUBJECT_SAMPLE_FACTORS           	PG_WT_SPM_b	HSA-000043756	Genotype:WT | Treatment:SPM | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_063.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_063.mzML
SUBJECT_SAMPLE_FACTORS           	PG_WT_22 6 PG_a	HSA-000043773	Genotype:WT | Treatment:22 6 PG | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_064.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_064.mzML
SUBJECT_SAMPLE_FACTORS           	PG_KO_DOPC_b	HSA-000043792	Genotype:ATP13A2 KO | Treatment:DOPC | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_065.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_065.mzML
SUBJECT_SAMPLE_FACTORS           	PG_KO_DOPC_a	HSA-000043791	Genotype:ATP13A2 KO | Treatment:DOPC | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_066.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_066.mzML
SUBJECT_SAMPLE_FACTORS           	PG_WT_a	HSA-000043752	Genotype:WT | Treatment:PBS | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_067.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_067.mzML
SUBJECT_SAMPLE_FACTORS           	PG_KO_b	HSA-000043777	Genotype:ATP13A2 KO | Treatment:PBS | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_069.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_069.mzML
SUBJECT_SAMPLE_FACTORS           	PG_KO_SPM_DOPC_b	HSA-000043783	Genotype:ATP13A2 KO | Treatment:SPM + DOPC | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_070.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_070.mzML
SUBJECT_SAMPLE_FACTORS           	PG_KO_SPM_c	HSA-000043781	Genotype:ATP13A2 KO | Treatment:SPM | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_071.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_071.mzML
SUBJECT_SAMPLE_FACTORS           	PG_WT_DOPC_a	HSA-000043767	Genotype:WT | Treatment:DOPC | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_072.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_072.mzML
SUBJECT_SAMPLE_FACTORS           	PG_WT_22 6 PG_b	HSA-000043774	Genotype:WT | Treatment:22 6 PG | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_075.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_075.mzML
SUBJECT_SAMPLE_FACTORS           	PG_WT_SPM_22 6 PG_b	HSA-000043765	Genotype:WT | Treatment:SPM + 22 6 PG | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_076.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_076.mzML
SUBJECT_SAMPLE_FACTORS           	PG_KO_SPM_a	HSA-000043779	Genotype:ATP13A2 KO | Treatment:SPM | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_077.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_077.mzML
SUBJECT_SAMPLE_FACTORS           	PG_KO_SPM_b	HSA-000043780	Genotype:ATP13A2 KO | Treatment:SPM | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_078.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_078.mzML
SUBJECT_SAMPLE_FACTORS           	PG_KO_SPM_22 6 PG_a	HSA-000043788	Genotype:ATP13A2 KO | Treatment:SPM + 22 6 PG | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_079.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_079.mzML
SUBJECT_SAMPLE_FACTORS           	Pool2_003	HSA-000043819	Genotype:NA | Treatment:NA | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=-; RAW_FILE_NAME(Raw Source Name.LN)=20250124_MS_HEX-000957_Lipid_Neg_080.mzML; RAW_FILE_NAME(Raw Source Name.MP)=-; RAW_FILE_NAME(Raw Source Name.MN)=-; RAW_FILE_NAME(Raw Source Name.HALO)=20250122_MS_HEX-000957_HALO_Pos_080.mzML
SUBJECT_SAMPLE_FACTORS           	Pool_Lyso_001	HSA-000038939	Genotype:NA | Treatment:NA | Sample source:HAP1 | Sample Type:lysosome	RAW_FILE_NAME(Raw Source Name.BZC)=20240905_MS_HEX-000820_PolyA_BzC_Pos_002.mzML; RAW_FILE_NAME(Raw Source Name.LN)=-; RAW_FILE_NAME(Raw Source Name.MP)=20240904_MS_HEX-000820_Met_Pos_002.mzML; RAW_FILE_NAME(Raw Source Name.MN)=20240905_MS_HEX-000820_Met_Neg_002.mzML; RAW_FILE_NAME(Raw Source Name.HALO)=-
SUBJECT_SAMPLE_FACTORS           	WT #1 Lyso	HSA-000038932	Genotype:WT | Treatment:none | Sample source:HAP1 | Sample Type:lysosome	RAW_FILE_NAME(Raw Source Name.BZC)=20240905_MS_HEX-000820_PolyA_BzC_Pos_003.mzML; RAW_FILE_NAME(Raw Source Name.LN)=-; RAW_FILE_NAME(Raw Source Name.MP)=20240904_MS_HEX-000820_Met_Pos_003.mzML; RAW_FILE_NAME(Raw Source Name.MN)=20240905_MS_HEX-000820_Met_Neg_003.mzML; RAW_FILE_NAME(Raw Source Name.HALO)=-
SUBJECT_SAMPLE_FACTORS           	WT #2 Lyso	HSA-000038933	Genotype:WT | Treatment:none | Sample source:HAP1 | Sample Type:lysosome	RAW_FILE_NAME(Raw Source Name.BZC)=20240905_MS_HEX-000820_PolyA_BzC_Pos_007.mzML; RAW_FILE_NAME(Raw Source Name.LN)=-; RAW_FILE_NAME(Raw Source Name.MP)=20240904_MS_HEX-000820_Met_Pos_007.mzML; RAW_FILE_NAME(Raw Source Name.MN)=20240905_MS_HEX-000820_Met_Neg_007.mzML; RAW_FILE_NAME(Raw Source Name.HALO)=-
SUBJECT_SAMPLE_FACTORS           	Pool_Lyso_002	HSA-000040325	Genotype:NA | Treatment:NA | Sample source:HAP1 | Sample Type:lysosome	RAW_FILE_NAME(Raw Source Name.BZC)=20240905_MS_HEX-000820_PolyA_BzC_Pos_008.mzML; RAW_FILE_NAME(Raw Source Name.LN)=-; RAW_FILE_NAME(Raw Source Name.MP)=20240904_MS_HEX-000820_Met_Pos_008.mzML; RAW_FILE_NAME(Raw Source Name.MN)=20240905_MS_HEX-000820_Met_Neg_008.mzML; RAW_FILE_NAME(Raw Source Name.HALO)=-
SUBJECT_SAMPLE_FACTORS           	WT #3 Lyso	HSA-000038934	Genotype:WT | Treatment:none | Sample source:HAP1 | Sample Type:lysosome	RAW_FILE_NAME(Raw Source Name.BZC)=20240905_MS_HEX-000820_PolyA_BzC_Pos_009.mzML; RAW_FILE_NAME(Raw Source Name.LN)=-; RAW_FILE_NAME(Raw Source Name.MP)=20240904_MS_HEX-000820_Met_Pos_009.mzML; RAW_FILE_NAME(Raw Source Name.MN)=20240905_MS_HEX-000820_Met_Neg_009.mzML; RAW_FILE_NAME(Raw Source Name.HALO)=-
SUBJECT_SAMPLE_FACTORS           	KO #2 Lyso	HSA-000038936	Genotype:ATP13A2 KO | Treatment:none | Sample source:HAP1 | Sample Type:lysosome	RAW_FILE_NAME(Raw Source Name.BZC)=20240905_MS_HEX-000820_PolyA_BzC_Pos_011.mzML; RAW_FILE_NAME(Raw Source Name.LN)=-; RAW_FILE_NAME(Raw Source Name.MP)=20240904_MS_HEX-000820_Met_Pos_011.mzML; RAW_FILE_NAME(Raw Source Name.MN)=20240905_MS_HEX-000820_Met_Neg_011.mzML; RAW_FILE_NAME(Raw Source Name.HALO)=-
SUBJECT_SAMPLE_FACTORS           	Pool_Lyso_003	HSA-000040326	Genotype:NA | Treatment:NA | Sample source:HAP1 | Sample Type:lysosome	RAW_FILE_NAME(Raw Source Name.BZC)=20240905_MS_HEX-000820_PolyA_BzC_Pos_016.mzML; RAW_FILE_NAME(Raw Source Name.LN)=-; RAW_FILE_NAME(Raw Source Name.MP)=20240904_MS_HEX-000820_Met_Pos_016.mzML; RAW_FILE_NAME(Raw Source Name.MN)=20240905_MS_HEX-000820_Met_Neg_016.mzML; RAW_FILE_NAME(Raw Source Name.HALO)=-
SUBJECT_SAMPLE_FACTORS           	KO #1 Lyso	HSA-000038935	Genotype:ATP13A2 KO | Treatment:none | Sample source:HAP1 | Sample Type:lysosome	RAW_FILE_NAME(Raw Source Name.BZC)=20240905_MS_HEX-000820_PolyA_BzC_Pos_019.mzML; RAW_FILE_NAME(Raw Source Name.LN)=-; RAW_FILE_NAME(Raw Source Name.MP)=20240904_MS_HEX-000820_Met_Pos_019.mzML; RAW_FILE_NAME(Raw Source Name.MN)=20240905_MS_HEX-000820_Met_Neg_019.mzML; RAW_FILE_NAME(Raw Source Name.HALO)=-
SUBJECT_SAMPLE_FACTORS           	KO #3 Lyso	HSA-000038937	Genotype:ATP13A2 KO | Treatment:none | Sample source:HAP1 | Sample Type:lysosome	RAW_FILE_NAME(Raw Source Name.BZC)=20240905_MS_HEX-000820_PolyA_BzC_Pos_022.mzML; RAW_FILE_NAME(Raw Source Name.LN)=-; RAW_FILE_NAME(Raw Source Name.MP)=20240904_MS_HEX-000820_Met_Pos_022.mzML; RAW_FILE_NAME(Raw Source Name.MN)=20240905_MS_HEX-000820_Met_Neg_022.mzML; RAW_FILE_NAME(Raw Source Name.HALO)=-
SUBJECT_SAMPLE_FACTORS           	Pool_Lyso_004	HSA-000040327	Genotype:NA | Treatment:NA | Sample source:HAP1 | Sample Type:lysosome	RAW_FILE_NAME(Raw Source Name.BZC)=20240905_MS_HEX-000820_PolyA_BzC_Pos_023.mzML; RAW_FILE_NAME(Raw Source Name.LN)=-; RAW_FILE_NAME(Raw Source Name.MP)=20240904_MS_HEX-000820_Met_Pos_023.mzML; RAW_FILE_NAME(Raw Source Name.MN)=20240905_MS_HEX-000820_Met_Neg_023.mzML; RAW_FILE_NAME(Raw Source Name.HALO)=-
SUBJECT_SAMPLE_FACTORS           	Pool_WCL_001	HSA-000038938	Genotype:NA | Treatment:NA | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=20240905_MS_HEX-000820_PolyA_BzC_Pos_024.mzML; RAW_FILE_NAME(Raw Source Name.LN)=-; RAW_FILE_NAME(Raw Source Name.MP)=20240904_MS_HEX-000820_Met_Pos_024.mzML; RAW_FILE_NAME(Raw Source Name.MN)=20240905_MS_HEX-000820_Met_Neg_024.mzML; RAW_FILE_NAME(Raw Source Name.HALO)=-
SUBJECT_SAMPLE_FACTORS           	KO #1 WCL	HSA-000038929	Genotype:ATP13A2 KO | Treatment:none | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=20240905_MS_HEX-000820_PolyA_BzC_Pos_028.mzML; RAW_FILE_NAME(Raw Source Name.LN)=-; RAW_FILE_NAME(Raw Source Name.MP)=20240904_MS_HEX-000820_Met_Pos_028.mzML; RAW_FILE_NAME(Raw Source Name.MN)=20240905_MS_HEX-000820_Met_Neg_028.mzML; RAW_FILE_NAME(Raw Source Name.HALO)=-
SUBJECT_SAMPLE_FACTORS           	KO #2 WCL	HSA-000038930	Genotype:ATP13A2 KO | Treatment:none | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=20240905_MS_HEX-000820_PolyA_BzC_Pos_029.mzML; RAW_FILE_NAME(Raw Source Name.LN)=-; RAW_FILE_NAME(Raw Source Name.MP)=20240904_MS_HEX-000820_Met_Pos_029.mzML; RAW_FILE_NAME(Raw Source Name.MN)=20240905_MS_HEX-000820_Met_Neg_029.mzML; RAW_FILE_NAME(Raw Source Name.HALO)=-
SUBJECT_SAMPLE_FACTORS           	KO #3 WCL	HSA-000038931	Genotype:ATP13A2 KO | Treatment:none | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=20240905_MS_HEX-000820_PolyA_BzC_Pos_030.mzML; RAW_FILE_NAME(Raw Source Name.LN)=-; RAW_FILE_NAME(Raw Source Name.MP)=20240904_MS_HEX-000820_Met_Pos_030.mzML; RAW_FILE_NAME(Raw Source Name.MN)=20240905_MS_HEX-000820_Met_Neg_030.mzML; RAW_FILE_NAME(Raw Source Name.HALO)=-
SUBJECT_SAMPLE_FACTORS           	Pool_WCL_002	HSA-000040322	Genotype:NA | Treatment:NA | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=20240905_MS_HEX-000820_PolyA_BzC_Pos_031.mzML; RAW_FILE_NAME(Raw Source Name.LN)=-; RAW_FILE_NAME(Raw Source Name.MP)=20240904_MS_HEX-000820_Met_Pos_031.mzML; RAW_FILE_NAME(Raw Source Name.MN)=20240905_MS_HEX-000820_Met_Neg_031.mzML; RAW_FILE_NAME(Raw Source Name.HALO)=-
SUBJECT_SAMPLE_FACTORS           	WT #2 WCL	HSA-000038927	Genotype:WT | Treatment:none | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=20240905_MS_HEX-000820_PolyA_BzC_Pos_036.mzML; RAW_FILE_NAME(Raw Source Name.LN)=-; RAW_FILE_NAME(Raw Source Name.MP)=20240904_MS_HEX-000820_Met_Pos_036.mzML; RAW_FILE_NAME(Raw Source Name.MN)=20240905_MS_HEX-000820_Met_Neg_036.mzML; RAW_FILE_NAME(Raw Source Name.HALO)=-
SUBJECT_SAMPLE_FACTORS           	WT #1 WCL	HSA-000038926	Genotype:WT | Treatment:none | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=20240905_MS_HEX-000820_PolyA_BzC_Pos_037.mzML; RAW_FILE_NAME(Raw Source Name.LN)=-; RAW_FILE_NAME(Raw Source Name.MP)=20240904_MS_HEX-000820_Met_Pos_037.mzML; RAW_FILE_NAME(Raw Source Name.MN)=20240905_MS_HEX-000820_Met_Neg_037.mzML; RAW_FILE_NAME(Raw Source Name.HALO)=-
SUBJECT_SAMPLE_FACTORS           	Pool_WCL_003	HSA-000040323	Genotype:NA | Treatment:NA | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=20240905_MS_HEX-000820_PolyA_BzC_Pos_038.mzML; RAW_FILE_NAME(Raw Source Name.LN)=-; RAW_FILE_NAME(Raw Source Name.MP)=20240904_MS_HEX-000820_Met_Pos_038.mzML; RAW_FILE_NAME(Raw Source Name.MN)=20240905_MS_HEX-000820_Met_Neg_038.mzML; RAW_FILE_NAME(Raw Source Name.HALO)=-
SUBJECT_SAMPLE_FACTORS           	WT #3 WCL	HSA-000038928	Genotype:WT | Treatment:none | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=20240905_MS_HEX-000820_PolyA_BzC_Pos_043.mzML; RAW_FILE_NAME(Raw Source Name.LN)=-; RAW_FILE_NAME(Raw Source Name.MP)=20240904_MS_HEX-000820_Met_Pos_043.mzML; RAW_FILE_NAME(Raw Source Name.MN)=20240905_MS_HEX-000820_Met_Neg_043.mzML; RAW_FILE_NAME(Raw Source Name.HALO)=-
SUBJECT_SAMPLE_FACTORS           	Pool_WCL_004	HSA-000040324	Genotype:NA | Treatment:NA | Sample source:HAP1 | Sample Type:whole cell lysate	RAW_FILE_NAME(Raw Source Name.BZC)=20240905_MS_HEX-000820_PolyA_BzC_Pos_045.mzML; RAW_FILE_NAME(Raw Source Name.LN)=-; RAW_FILE_NAME(Raw Source Name.MP)=20240904_MS_HEX-000820_Met_Pos_045.mzML; RAW_FILE_NAME(Raw Source Name.MN)=20240905_MS_HEX-000820_Met_Neg_045.mzML; RAW_FILE_NAME(Raw Source Name.HALO)=-
#COLLECTION
CO:COLLECTION_SUMMARY            	Human HAP1 parental WT and ATP13A2 KO cells (~25,000) were washed 1x with 0.9%
CO:COLLECTION_SUMMARY            	sodium chloride and harvested for metabolite and lipid extraction. Lysosomal
CO:COLLECTION_SUMMARY            	fractions were isolated from HAP1 parental WT and ATP13A2 KO cells following
CO:COLLECTION_SUMMARY            	endocytosis-mediated labeling using superparamagnetic iron oxide nanoparticles
CO:COLLECTION_SUMMARY            	(SPION). HAP1 cells were seeded in 3X 10cm tissue culture dishes and allowed to
CO:COLLECTION_SUMMARY            	grow till ~75% confluency at which time they were treated for 24 h with 10%
CO:COLLECTION_SUMMARY            	(v/v) dextran-magnetite solution (DexoMAG40, Liquids Research Ltd.). The cells
CO:COLLECTION_SUMMARY            	were rinsed with warmed 1X PBS, pH 7.4 (Gibco; # 10010023) to remove residual
CO:COLLECTION_SUMMARY            	extracellular dextran-magnetite and re-supplemented with fresh culture medium
CO:COLLECTION_SUMMARY            	for at least 4 h to allow for specific labeling of lysosomes and late endosomes.
CO:COLLECTION_SUMMARY            	Cells were harvested by scraping with ice cold 1X PBS and centrifugation at 300
CO:COLLECTION_SUMMARY            	x g for 5 min at 4°C; resuspended in isolation buffer (250mM sucrose, 10 mM
CO:COLLECTION_SUMMARY            	HEPES, 1 mM CaCl2, 1 mM MgCl2, 1 mM DTT, cOmplete Protease Inhibitor (Roche;
CO:COLLECTION_SUMMARY            	#04693132001)), and replicates pooled by centrifugation into 1 mL lysis buffer.
CO:COLLECTION_SUMMARY            	Cells were lysed using a 27G needle for 20 strokes, followed by centrifugation
CO:COLLECTION_SUMMARY            	of the cell lysate at 600 x g for 10 min at 4°C. Post-nuclear supernatant (PNS)
CO:COLLECTION_SUMMARY            	was collected, and pellet was resuspended in 1 mL isolation buffer followed by
CO:COLLECTION_SUMMARY            	another round of needle lysis and PNS collection to capture maximum lysosomes.
CO:COLLECTION_SUMMARY            	Pooled supernatants from both rounds of needle lysis were then loaded onto LS
CO:COLLECTION_SUMMARY            	columns (Miltenyi Biotec; #130-042-401), attached to Quadro MACS magnet, that
CO:COLLECTION_SUMMARY            	were already pre equilibrated with chilled isolation buffer. Flowthrough was
CO:COLLECTION_SUMMARY            	collected after passing the PNS through the column by gravity flow and passed
CO:COLLECTION_SUMMARY            	through the column again to increase retention of unbound labeled lysosomes.
CO:COLLECTION_SUMMARY            	Finally, the columns were washed three times with isolation buffer to eliminate
CO:COLLECTION_SUMMARY            	other membrane-bound organelle contaminants, and magnetically bound lysosomes
CO:COLLECTION_SUMMARY            	eluted twice into 0.5 mL isolation buffer. The elutes were diluted with 1 mL 1X
CO:COLLECTION_SUMMARY            	PBS, centrifuged at 21,000 x g for 40 min at 4°C. The lysosomal pellet was
CO:COLLECTION_SUMMARY            	resuspended in 200 µL isolation buffer and harvested for metabolite and lipid
CO:COLLECTION_SUMMARY            	extraction.
CO:SAMPLE_TYPE                   	HAP1 cells
CO:STORAGE_CONDITIONS            	-80℃
CO:COLLECTION_VIALS              	Lobind 1.5 mL Eppendorf tubes
CO:STORAGE_VIALS                 	Lobind 1.5 mL Eppendorf tubes
#TREATMENT
TR:TREATMENT_SUMMARY             	Human HAP1 parental WT and ATP13A2 KO cells (Horizon Discovery; WT: C631;
TR:TREATMENT_SUMMARY             	ATP13A2 KO: HZGHC003547c002) were cultured in Iscove’s Modified Dulbecco’s
TR:TREATMENT_SUMMARY             	Medium (IMDM, Gibco; #12440053) supplemented with 10% fetal bovine serum (VWR
TR:TREATMENT_SUMMARY             	Seradigm; #97068-085) and 1% Penicillin/Streptomycin (Gibco; #15140122). No
TR:TREATMENT_SUMMARY             	treatment.Cells were treated for 20 hours with PBS, Rimeporide(Rim), Spermine
TR:TREATMENT_SUMMARY             	(SPM), or a combination of Spermine (SPM) + Rimeporide(Rim), followed by
TR:TREATMENT_SUMMARY             	metabolite extraction. Cells were treated for 20 hours with PBS , Spermine
TR:TREATMENT_SUMMARY             	(SPM), 18:1 (Δ9-Cis) PC (DOPC), 22:6 PG, a combination of Spermine(SPM) + DOPC,
TR:TREATMENT_SUMMARY             	or a combination of Spermine (SPM) + 22:6 PG,followed by metabolite extraction.
TR:TREATMENT_SUMMARY             	NOTE: To evaluate whether BMP can rescue spermine-dependent inhibition, WT HAP1
TR:TREATMENT_SUMMARY             	cells were treated with spermine and supplemented with PG(22:6/22:6), a
TR:TREATMENT_SUMMARY             	structural isomer and precursor of BMP(22:6/22:6). PG (22:6/22:6) was
TR:TREATMENT_SUMMARY             	supplemented due to its lower cost and greater availability, relying on its
TR:TREATMENT_SUMMARY             	established rapid conversion to BMP in lysosomes (see
TR:TREATMENT_SUMMARY             	10.1016/j.bbalip.2021.158916).
#SAMPLEPREP
SP:SAMPLEPREP_SUMMARY            	Cells (~25,000) and lysosomal fractions (100 µg) were directly lysed and
SP:SAMPLEPREP_SUMMARY            	extracted in 150 µL methanol containing stable-isotope internal standards for
SP:SAMPLEPREP_SUMMARY            	20 min at 4°C with shaking. The supernatant fraction was transferred to a
SP:SAMPLEPREP_SUMMARY            	96-well sample collection plate (Waters; #186005837) following a 14,000 x g spin
SP:SAMPLEPREP_SUMMARY            	at 4°C for 20 min from which the supernatant was distributed for the LC-MS/MS
SP:SAMPLEPREP_SUMMARY            	analyses.
SP:PROCESSING_STORAGE_CONDITIONS 	On ice
SP:EXTRACT_STORAGE               	-20℃
#CHROMATOGRAPHY
CH:CHROMATOGRAPHY_TYPE           	Reversed phase
CH:INSTRUMENT_NAME               	Agilent 1290 Infinity II
CH:COLUMN_NAME                   	Waters ACQUITY UPLC BEH C18 (100 x 2.1mm,1.7um)
CH:SOLVENT_A                     	60% acetonitrile/40% water; 10 mM ammonium acetate; 0.1% acetic acid
CH:SOLVENT_B                     	90% isopropyl alcohol/10% acetonitrile; 10 mM ammonium acetate; 0.1% acetic acid
CH:FLOW_GRADIENT                 	0.0-8.0 min from 45% B to 99% B, 8.0-9.0 min at 99% B, 9.0-9.1 min to 45% B, and
CH:FLOW_GRADIENT                 	9.1-10.0 min at 45% B.
CH:FLOW_RATE                     	0.25 mL/min
CH:COLUMN_TEMPERATURE            	55
CH:SAMPLE_INJECTION              	5
#ANALYSIS
AN:ANALYSIS_TYPE                 	MS
#MS
MS:INSTRUMENT_NAME               	ABI Sciex 6500+ QTrap
MS:INSTRUMENT_TYPE               	Triple quadrupole
MS:MS_TYPE                       	ESI
MS:ION_MODE                      	NEGATIVE
MS:MS_COMMENTS                   	curtain gas at 30 psi; collision gas set at medium; ion spray voltage at 4,500
MS:MS_COMMENTS                   	V; temperature at 600°C; ion source Gas 1 at 55 psi; ion source Gas 2 at 60
MS:MS_COMMENTS                   	psi.
#MS_METABOLITE_DATA
MS_METABOLITE_DATA:UNITS	normalized peak area
MS_METABOLITE_DATA_START
Samples	HSA-000043814	HSA-000043739	HSA-000043726	HSA-000043729	HSA-000043743	HSA-000043736	HSA-000043747	HSA-000043731	HSA-000043732	HSA-000043735	HSA-000043742	HSA-000043746	HSA-000043737	HSA-000043815	HSA-000043733	HSA-000043740	HSA-000043728	HSA-000043730	HSA-000043748	HSA-000043744	HSA-000043725	HSA-000043727	HSA-000043734	HSA-000043741	HSA-000043745	HSA-000043738	HSA-000043816	HSA-000043817	HSA-000043754	HSA-000043759	HSA-000043798	HSA-000043769	HSA-000043778	HSA-000043797	HSA-000043789	HSA-000043757	HSA-000043760	HSA-000043776	HSA-000043775	HSA-000043755	HSA-000043753	HSA-000043799	HSA-000043782	HSA-000043768	HSA-000043766	HSA-000043758	HSA-000043818	HSA-000043764	HSA-000043790	HSA-000043784	HSA-000043793	HSA-000043756	HSA-000043773	HSA-000043792	HSA-000043791	HSA-000043752	HSA-000043777	HSA-000043783	HSA-000043781	HSA-000043767	HSA-000043774	HSA-000043765	HSA-000043779	HSA-000043780	HSA-000043788
Factors	Genotype:NA | Treatment:NA | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:ATP13A2 KO | Treatment:PBS | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:WT | Treatment:PBS | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:WT | Treatment:SPM | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:ATP13A2 KO | Treatment:Rim | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:WT | Treatment:SPM + Rim | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:ATP13A2 KO | Treatment:SPM + Rim | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:WT | Treatment:Rim | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:WT | Treatment:Rim | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:WT | Treatment:SPM + Rim | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:ATP13A2 KO | Treatment:SPM | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:ATP13A2 KO | Treatment:SPM + Rim | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:ATP13A2 KO | Treatment:PBS | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:NA | Treatment:NA | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:WT | Treatment:Rim | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:ATP13A2 KO | Treatment:SPM | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:WT | Treatment:SPM | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:WT | Treatment:SPM | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:ATP13A2 KO | Treatment:SPM + Rim | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:ATP13A2 KO | Treatment:Rim | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:WT | Treatment:PBS | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:WT | Treatment:PBS | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:WT | Treatment:SPM + Rim | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:ATP13A2 KO | Treatment:SPM | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:ATP13A2 KO | Treatment:Rim | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:ATP13A2 KO | Treatment:PBS | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:NA | Treatment:NA | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:NA | Treatment:NA | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:WT | Treatment:PBS | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:WT | Treatment:SPM + DOPC | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:ATP13A2 KO | Treatment:22 6 PG | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:WT | Treatment:DOPC | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:ATP13A2 KO | Treatment:PBS | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:ATP13A2 KO | Treatment:22 6 PG | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:ATP13A2 KO | Treatment:SPM + 22 6 PG | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:WT | Treatment:SPM | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:WT | Treatment:SPM + DOPC | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:ATP13A2 KO | Treatment:PBS | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:WT | Treatment:22 6 PG | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:WT | Treatment:SPM | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:WT | Treatment:PBS | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:ATP13A2 KO | Treatment:22 6 PG | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:ATP13A2 KO | Treatment:SPM + DOPC | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:WT | Treatment:DOPC | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:WT | Treatment:SPM + 22 6 PG | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:WT | Treatment:SPM + DOPC | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:NA | Treatment:NA | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:WT | Treatment:SPM + 22 6 PG | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:ATP13A2 KO | Treatment:SPM + 22 6 PG | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:ATP13A2 KO | Treatment:SPM + DOPC | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:ATP13A2 KO | Treatment:DOPC | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:WT | Treatment:SPM | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:WT | Treatment:22 6 PG | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:ATP13A2 KO | Treatment:DOPC | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:ATP13A2 KO | Treatment:DOPC | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:WT | Treatment:PBS | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:ATP13A2 KO | Treatment:PBS | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:ATP13A2 KO | Treatment:SPM + DOPC | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:ATP13A2 KO | Treatment:SPM | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:WT | Treatment:DOPC | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:WT | Treatment:22 6 PG | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:WT | Treatment:SPM + 22 6 PG | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:ATP13A2 KO | Treatment:SPM | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:ATP13A2 KO | Treatment:SPM | Sample source:HAP1 | Sample Type:whole cell lysate	Genotype:ATP13A2 KO | Treatment:SPM + 22 6 PG | Sample source:HAP1 | Sample Type:whole cell lysate
3-O-SulfoGalCer(d18:1/16:0)	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
3-O-SulfoGalCer(d18:1/18:0(2OH)	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
3-O-SulfoGalCer(d18:1/18:0(d3))	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
3-O-SulfoGalCer(d18:1/18:0)	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
3-O-SulfoGalCer(d18:1/24:0(2OH))	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
3-O-SulfoGalCer(d18:1/24:0)	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
3-O-SulfoGalCer(d18:1/24:1(2OH))	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
3-O-SulfoGalCer(d18:1/24:1)	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
Arachidonic acid	0.107	0.244	0.13	0.398	0.211	0.41	0.463	0.229	0.179	0.25	0.497	0.389	0.327	0.157	0.193	0.457	0.766	0.258	0.637	0.285	0.243	0.057	0.617	0.531	0.312	0.312	0.079	0.153	0.111	0.106	N.D.	0.099	0.161	N.D.	0.22	0.104	0.069	0.131	0.123	0.115	0.129	N.D.	0.12	0.102	0.114	0.098	0.177	0.169	0.317	0.152	0.121	0.114	0.169	0.158	0.161	0.083	0.115	0.094	0.288	0.104	0.157	0.108	0.132	0.193	0.197
Arachidonic acid-d8	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
Arachidonic acid-d8_MRM	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
BMP(14:0/14:0)	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
BMP(16:0_18:1)	0.024	0.053	0.097	0.029	0.027	0.045	0.029	0.077	0.08	0.042	0.023	0.021	0.043	0.022	0.07	0.023	0.005	0.044	0.024	0.021	0.07	0.109	0.043	0.024	0.032	0.084	0.023	0.063	0.031	0.044	N.D.	0.026	0.024	N.D.	0.035	0.022	0.032	0.022	0.052	0.031	0.058	N.D.	0.048	0.042	0.063	0.05	0.053	0.04	0.033	0.035	0.039	0.036	0.042	0.02	0.025	0.036	0.017	0.037	0.017	0.051	0.047	0.041	0.018	0.028	0.042
BMP(16:0_20:4)	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
BMP(16:0_22:6)	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
BMP(16:1/16:1)	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
BMP(18:0_18:1)	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
BMP(18:0_20:4)	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
BMP(18:0_22:6)	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
BMP(18:1/18:1)	0.307	0.707	1.309	0.885	0.27	0.414	0.281	0.785	0.875	0.405	0.317	0.316	0.654	0.247	0.708	0.448	0.291	0.721	0.254	0.193	1.26	1.189	0.453	1.249	0.3	1.159	0.317	305.884	0.434	17.629	N.D.	2.404	0.416	N.D.	2.056	0.318	2.877	0.299	2.907	0.371	0.693	N.D.	24.796	1.309	1.424	35.645	221.825	4.07	7.222	0.424	5.487	0.504	3.311	3.467	0.747	0.534	0.343	16.832	0.365	1.271	2.308	1.931	0.287	1.065	3.037
BMP(20:4/20:4)	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
BMP(22:6/22:6)	0.103	0.271	0.22	0.138	0.272	0.203	0.182	0.271	0.297	0.203	0.137	0.245	0.255	0.079	0.296	0.139	0.022	0.174	0.138	0.198	0.242	0.239	0.158	0.151	0.289	0.33	0.074	0.257	0.107	0.105	N.D.	0.11	0.074	N.D.	0.606	0.12	0.088	0.124	0.572	0.077	0.106	N.D.	0.095	0.075	0.894	0.112	0.228	0.952	0.532	0.097	0.093	0.123	1.456	0.109	0.09	0.155	0.112	0.095	0.104	0.136	1.31	0.84	0.11	0.288	0.68
CL(14:0/14:0/14:0/14:0)	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
CL(72:6/18:2)	0.382	1.061	0.974	0.525	0.903	0.688	0.563	1.111	1.105	0.639	0.585	0.694	0.821	0.424	1.132	0.654	0.124	0.704	0.491	0.779	0.746	1.023	0.662	0.715	0.852	1.189	0.34	0.509	0.647	0.595	N.D.	0.499	0.466	N.D.	0.388	0.565	0.631	0.595	0.677	0.442	0.64	N.D.	0.471	0.531	0.564	0.515	0.466	0.624	0.39	0.475	0.415	0.538	0.631	0.425	0.344	0.596	0.566	0.579	0.457	0.603	0.797	0.582	0.399	0.423	0.402
CL(72:7/18:2)	0.12	0.539	0.331	0.166	0.277	0.237	0.173	0.472	0.466	0.304	0.238	0.235	0.363	0.144	0.405	0.214	0.078	0.205	0.174	0.294	0.387	0.498	0.366	0.242	0.361	0.349	0.15	0.138	0.267	0.18	N.D.	0.208	0.19	N.D.	0.16	0.17	0.205	0.175	0.21	0.177	0.197	N.D.	0.189	0.19	0.192	0.198	0.15	0.229	0.131	0.2	0.117	0.172	0.226	0.163	0.196	0.202	0.225	0.241	0.216	0.271	0.192	0.276	0.22	0.202	0.108
CL(72:8-2(OOH)/18:2)	N.D.	0.12	0.06	0.054	0.11	0.052	0.06	0.094	0.09	0.069	0.07	0.112	0.086	0.018	0.084	0.052	0.02	0.065	0.045	0.066	0.051	0.044	0.042	0.05	0.084	0.097	N.D.	0.054	0.022	0.027	N.D.	0.045	0.042	N.D.	0.059	0.039	N.D.	0.052	0.056	0.036	0.033	N.D.	0.052	0.048	N.D.	0.036	0.028	0.041	N.D.	0.03	0.039	0.018	0.032	0.047	0.065	0.052	0.045	0.058	0.033	0.04	0.02	N.D.	0.037	0.066	0.012
CL(72:8/18:2)	0.093	0.242	0.236	0.124	0.183	0.095	0.079	0.193	0.256	0.096	0.109	0.103	0.177	0.062	0.221	0.084	0.03	0.141	0.085	0.139	0.164	0.269	0.133	0.109	0.223	0.239	0.074	0.093	0.092	0.117	N.D.	0.109	0.114	N.D.	0.062	0.139	0.07	0.139	0.118	0.088	0.157	N.D.	0.059	0.073	0.088	0.05	0.078	0.097	0.067	0.101	0.056	0.073	0.09	0.087	0.087	0.135	0.093	0.089	0.074	0.094	0.123	0.081	0.063	0.07	0.084
CL(74:9/18:2)	0.023	0.176	0.127	0.053	0.116	0.118	0.107	0.138	0.196	0.048	0.074	0.038	0.157	0.036	0.136	0.026	N.D.	0.134	0.07	0.123	0.109	0.209	0.095	0.065	0.175	0.174	0.05	0.046	0.1	0.107	N.D.	0.077	0.1	N.D.	0.031	0.063	N.D.	0.103	0.108	0.076	0.105	N.D.	0.036	0.063	0.047	0.069	0.062	0.08	0.048	0.063	0.098	0.052	0.108	0.114	0.108	0.096	0.112	0.058	0.079	0.099	0.07	0.093	0.093	0.042	0.048
Cholesterol sulfate	1.447	2.359	1.965	2.176	1.7	2.378	2.021	2.969	2.591	1.969	2.523	2.438	2.916	1.235	2.807	1.951	1.842	2.986	2.079	1.855	1.7	2.069	1.968	2.106	3.276	1.713	0.465	0.874	0.709	0.73	N.D.	1.744	0.899	N.D.	0.548	1.189	0.758	1.339	0.724	0.568	0.774	N.D.	0.813	0.652	0.672	0.851	1.472	0.838	0.795	0.733	0.764	0.861	1.544	1.302	0.731	0.62	1.309	0.893	2.348	0.824	1.736	0.984	1.498	0.989	0.722
Docosahexaenoic acid	0.058	0.145	0.082	0.147	0.138	0.111	0.149	0.133	0.176	0.131	0.217	0.169	0.106	0.052	0.109	0.159	0.108	0.151	0.161	0.158	0.063	0.075	0.079	0.197	0.118	0.086	0.047	0.104	0.064	0.066	N.D.	0.084	0.06	N.D.	0.21	0.069	0.072	0.072	0.301	0.067	0.037	N.D.	0.045	0.054	0.193	0.07	0.095	0.172	0.291	0.066	0.082	0.059	0.276	0.081	0.066	0.045	0.073	0.066	0.095	0.062	0.258	0.178	0.099	0.128	0.189
Eicosapentaenoic acid	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
FAHFA(18:1/9-O-18:0)	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
GD1a/b(d36:1)	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
GD3(d34:1)	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
GD3(d36:1)	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
GM3(d18:1/18:0(d5))	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
GM3(d34:1)	0.475	1.697	1.769	0.807	0.649	0.82	0.753	1.515	1.407	0.768	0.981	0.743	1.614	0.483	1.44	0.839	0.428	0.935	0.958	0.614	1.495	2.102	0.612	0.86	1.127	1.622	0.33	0.699	0.681	0.52	N.D.	0.612	0.631	N.D.	0.394	0.614	0.367	0.686	0.527	0.673	0.591	N.D.	0.49	0.521	0.317	0.377	0.481	0.424	0.348	0.502	0.619	0.578	0.652	0.687	0.502	0.69	0.595	0.644	0.428	0.657	0.678	0.408	0.533	0.616	0.375
GM3(d36:1)	0.14	0.341	0.305	0.201	0.155	0.246	0.166	0.282	0.349	0.219	0.217	0.185	0.32	0.12	0.342	0.194	0.136	0.248	0.288	0.154	0.404	0.368	0.232	0.182	0.236	0.348	0.084	0.174	0.215	0.133	N.D.	0.201	0.174	N.D.	0.11	0.148	0.136	0.166	0.135	0.18	0.194	N.D.	0.159	0.172	0.148	0.13	0.233	0.113	0.165	0.152	0.184	0.114	0.201	0.152	0.125	0.213	0.162	0.2	0.152	0.191	0.175	0.128	0.115	0.174	0.093
GQ1b(d36:1)	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
Hemi-BMP(14:0/14:0)_14:0	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
Hemi-BMP(18:1/18:1)_16:0	0.002	0.006	0.008	0.004	0.003	0.007	0.001	0.008	0.004	0.005	0.003	0.004	0.007	0.001	0.009	0.004	0.001	0.002	0.002	0.004	0.008	0.007	0.004	0.004	0.004	0.007	0.004	0.006	0.005	0.002	N.D.	0.005	0.003	N.D.	0.004	0.004	0.005	0.002	0.005	0.002	0.004	N.D.	0.003	0.003	0.003	0.002	0.007	0.001	N.D.	0.002	0.003	0.003	0.003	0.005	0.002	0.003	0.001	0.002	0.003	0.004	0.004	0.004	0.001	0.003	0.001
Hemi-BMP(18:1/18:1)_18:0	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
Hemi-BMP(18:1/18:1)_18:1	N.D.	0.001	N.D.	0.002	0.002	0.002	0.002	N.D.	0.001	N.D.	N.D.	0.003	0.001	0.001	0.004	0.002	N.D.	0.001	N.D.	0.001	0.001	N.D.	0.002	0.002	N.D.	N.D.	N.D.	0.293	N.D.	0.013	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	0.014	N.D.	N.D.	0.02	0.225	N.D.	0.002	N.D.	0.004	N.D.	0.003	0.003	N.D.	N.D.	N.D.	0.014	N.D.	N.D.	N.D.	0.002	N.D.	N.D.	0.002
Hemi-BMP(20:4/20:4)_16:0	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
Hemi-BMP(20:4/20:4)_18:0	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
Hemi-BMP(20:4/20:4)_18:1	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
Hemi-BMP(20:4/20:4)_20:4	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
Hemi-BMP(22:6/22:6)_16:0	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
Hemi-BMP(22:6/22:6)_18:0	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
Hemi-BMP(22:6/22:6)_18:1	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
Hemi-BMP(22:6/22:6)_22:6	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
LPE(16:0)	0.173	0.17	0.165	0.104	0.175	0.124	0.136	0.182	0.191	0.109	0.139	0.157	0.17	0.12	0.166	0.123	0.065	0.093	0.108	0.147	0.137	0.113	0.14	0.105	0.199	0.172	0.135	0.102	0.066	0.053	N.D.	0.066	0.089	N.D.	0.062	0.056	0.077	0.062	0.074	0.054	0.093	N.D.	0.073	0.093	0.047	0.056	0.078	0.052	0.089	0.076	0.073	0.07	0.071	0.084	0.073	0.053	0.061	0.058	0.08	0.074	0.069	0.049	0.062	0.068	0.056
LPE(18:0)	0.582	1.461	1.514	0.745	1.266	1.022	0.886	1.339	1.518	0.812	0.708	0.963	1.181	0.604	1.752	0.787	0.439	0.613	0.826	1.242	1.886	1.379	1.174	0.906	1.213	1.549	0.568	0.739	0.68	0.686	N.D.	0.546	0.675	N.D.	0.471	0.454	0.549	0.462	0.639	0.462	0.683	N.D.	0.662	0.582	0.602	0.456	0.514	0.593	0.616	0.595	0.532	0.656	0.596	0.497	0.599	0.548	0.466	0.545	0.418	0.665	0.571	0.572	0.387	0.474	0.562
LPE(18:1(d7))	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
LPG(16:0)	0.014	0.019	0.022	0.019	0.021	0.014	0.01	0.03	0.024	0.019	0.011	0.023	0.026	0.008	0.025	0.01	N.D.	0.018	0.021	0.014	0.029	0.025	0.015	0.025	0.028	0.023	0.006	0.019	0.019	0.017	N.D.	0.026	0.017	N.D.	0.019	0.021	0.01	0.025	0.027	0.015	0.012	N.D.	0.018	0.02	0.028	0.017	0.022	0.039	0.043	0.018	0.018	0.015	0.035	0.02	0.019	0.022	0.016	0.02	0.013	0.014	0.044	0.03	0.011	0.017	0.019
LPG(18:0)	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
LPG(18:1)	0.037	0.144	0.169	0.087	0.071	0.088	0.046	0.135	0.079	0.064	0.073	0.1	0.154	0.049	0.101	0.067	0.044	0.091	0.075	0.056	0.152	0.155	0.088	0.072	0.096	0.141	0.044	3.705	0.178	0.245	N.D.	0.189	0.143	N.D.	0.262	0.141	0.18	0.155	0.296	0.108	0.128	N.D.	0.271	0.137	0.291	0.313	3.823	0.342	0.406	0.112	0.139	0.166	0.416	0.157	0.174	0.172	0.166	0.227	0.105	0.186	0.426	0.258	0.142	0.183	0.236
LPG(20:4)	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
LPG(22:6)	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
LPI(16:0)	0.014	0.029	0.023	0.018	0.031	0.018	0.009	0.033	0.032	0.015	0.015	0.011	0.028	0.011	0.019	0.01	0.013	0.016	0.009	0.015	0.023	0.033	N.D.	0.007	0.032	0.022	0.008	0.017	0.014	0.012	N.D.	0.013	0.017	N.D.	0.012	0.017	0.006	0.018	0.013	0.009	N.D.	N.D.	N.D.	N.D.	N.D.	0.008	0.015	0.011	0.02	0.01	0.01	0.008	0.015	0.012	0.006	0.017	0.011	0.015	0.011	0.015	0.016	0.009	0.013	0.013	0.005
LPI(18:0)	0.099	0.198	0.248	0.124	0.128	0.167	0.122	0.245	0.235	0.136	0.171	0.179	0.216	0.09	0.182	0.136	0.075	0.137	0.102	0.119	0.162	0.192	0.166	0.11	0.166	0.177	0.099	0.08	0.07	0.079	N.D.	0.094	0.075	N.D.	0.046	0.083	0.086	0.084	0.064	0.073	0.073	N.D.	0.064	0.065	0.071	0.063	0.092	0.088	0.089	0.07	0.05	0.079	0.124	0.07	0.068	0.076	0.094	0.07	0.066	0.091	0.118	0.099	0.073	0.078	0.049
Linoleic acid	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
Linolenic acid	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
Oleic acid	0.608	1.49	0.915	1.558	1.068	0.975	0.975	0.95	0.791	0.989	1.091	0.817	0.958	0.51	0.695	0.948	1.077	0.815	1.396	1.269	1.15	1.15	1.089	1.374	0.809	0.99	0.902	1.848	0.717	0.878	N.D.	0.683	0.871	N.D.	0.854	0.659	0.852	0.937	0.893	1.001	0.642	N.D.	1.134	0.852	1.652	1.862	1.473	0.887	1.075	1.051	0.699	0.985	1.838	0.677	0.963	1.297	0.718	0.838	3.329	1.524	1.183	1.058	0.887	0.846	0.81
PA(15:0/18:1(d7))	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
PA(16:0_18:1)	0.432	0.993	1.206	0.626	0.81	0.694	0.644	1.216	0.93	0.529	0.581	0.823	1.326	0.41	0.946	0.76	0.373	0.684	0.58	0.723	1.411	0.983	0.846	0.587	0.876	1.113	0.494	0.364	0.475	0.408	N.D.	0.44	0.283	N.D.	0.344	0.422	0.303	0.364	0.385	0.42	0.508	N.D.	0.402	0.41	0.384	0.461	0.336	0.366	0.275	0.232	0.245	0.34	0.317	0.311	0.272	0.486	0.35	0.405	0.279	0.312	0.453	0.299	0.29	0.264	0.234
PA(18:0_18:1)	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
PA(18:0_20:4)	0.078	0.234	0.197	0.174	0.19	0.123	0.181	N.D.	0.19	0.166	0.126	0.182	0.332	0.091	0.218	0.233	0.103	0.166	0.114	0.186	0.334	0.171	0.183	0.179	0.226	0.268	0.089	0.152	0.113	0.084	N.D.	0.089	0.086	N.D.	0.105	0.097	0.097	0.082	0.068	0.104	0.115	N.D.	0.106	0.105	0.089	0.109	0.133	0.088	0.07	0.108	0.072	0.09	0.106	0.068	0.112	0.13	0.135	0.114	0.099	0.094	0.095	0.122	N.D.	0.056	0.088
PA(18:0_22:6)	0.111	0.335	0.399	0.121	0.196	0.205	0.13	0.371	0.326	0.197	0.087	0.107	0.29	0.079	0.326	0.158	0.069	0.155	0.158	0.148	0.317	0.404	0.158	0.105	0.203	0.259	0.095	0.087	0.098	0.081	N.D.	0.104	0.074	N.D.	N.D.	0.087	0.095	0.107	0.171	0.106	0.107	N.D.	N.D.	0.124	0.084	0.1	0.097	0.109	0.073	0.077	0.075	N.D.	0.148	0.094	0.076	0.102	0.102	0.095	0.084	0.096	0.163	0.151	0.088	0.091	0.071
PA(18:1/18:1)	0.324	0.657	0.789	0.433	0.598	0.4	0.368	0.669	0.652	0.385	0.4	0.523	0.989	0.27	0.627	0.644	0.209	0.468	0.343	0.492	1.041	0.589	0.565	0.403	0.67	0.722	0.303	0.422	0.378	0.363	N.D.	0.357	0.283	N.D.	0.299	0.376	0.337	0.323	0.481	0.351	0.455	N.D.	0.325	0.356	0.332	0.438	0.39	0.369	0.179	0.3	0.189	0.327	0.407	0.272	0.268	0.486	0.229	0.385	0.227	0.317	0.336	0.393	0.21	0.25	0.203
PE(15:0/18:1(d7))	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
PE(O-16:0/20:4)	1.02	3.234	2.928	2.149	2.437	2.757	2.148	3.07	3.204	2.493	2.219	2.61	2.792	0.981	2.968	2.514	1.819	2.605	2.01	1.887	2.274	2.568	2.322	2.228	2.432	3.186	1.152	1.272	1.169	1.211	N.D.	1.188	1.347	N.D.	1.262	1.067	1.184	1.303	1.115	1.112	1.154	N.D.	1.27	1.166	1.227	1.075	1.226	1.151	1.224	1.51	1.285	1.123	1.495	1.173	1.239	1.17	1.292	1.28	1.236	1.201	1.337	1.111	1.261	1.201	1.245
PE(O-16:0/22:6)	0.24	0.715	0.695	0.26	0.468	0.383	0.269	0.586	0.583	0.354	0.325	0.441	0.653	0.266	0.574	0.325	0.135	0.391	0.211	0.37	0.508	0.559	0.313	0.299	0.502	0.752	0.244	0.229	0.259	0.207	N.D.	0.242	0.195	N.D.	0.228	0.239	0.22	0.232	0.309	0.2	0.268	N.D.	0.204	0.261	0.324	0.235	0.213	0.315	0.227	0.254	0.199	0.224	0.458	0.188	0.205	0.29	0.23	0.22	0.192	0.23	0.36	0.353	0.188	0.188	0.199
PE(O-18:0/20:4)	1.018	2.834	3.049	2.15	2.038	2.301	2.191	2.95	2.988	2.138	2.287	2.327	2.719	0.906	2.827	2.498	2.149	2.736	1.79	1.59	2.43	2.578	2.237	2.191	2.127	3.007	0.965	1.464	1.229	1.421	N.D.	1.381	1.356	N.D.	1.502	1.168	1.345	1.329	1.319	1.201	1.263	N.D.	1.404	1.368	1.477	1.278	1.476	1.457	1.573	1.647	1.467	1.153	1.607	1.31	1.629	1.165	1.327	1.38	1.414	1.344	1.571	1.314	1.193	1.14	1.384
PE(O-18:0/22:6)	0.1	0.375	0.454	0.223	0.258	0.269	0.198	0.361	0.417	0.23	0.211	0.188	0.371	0.137	0.358	0.208	0.14	0.271	0.182	0.174	0.324	0.392	0.216	0.224	0.277	0.373	0.158	0.141	0.146	0.146	N.D.	0.126	0.125	N.D.	0.152	0.142	0.12	0.122	0.2	0.109	0.128	N.D.	0.136	0.141	0.215	0.128	0.13	0.204	0.177	0.154	0.163	0.137	0.281	0.115	0.114	0.128	0.145	0.152	0.101	0.131	0.241	0.205	0.115	0.124	0.149
PE(P-16:0/20:4)	16.738	48.554	47.742	27.77	37.171	33.617	28.713	47.296	49.392	32.468	29.331	35.293	43.327	14.935	45.833	29.657	11.309	35.269	26.997	30.399	38.006	42.684	25.691	29.281	37.996	49.716	16.532	17.648	20.067	19.177	N.D.	19.017	18.883	N.D.	17.88	17.203	16.3	18.756	17.049	18.041	19.914	N.D.	17.161	20.316	18.583	17.819	17.555	18.054	15.431	22.036	17.109	17.175	21.667	17.728	18.546	19.643	19.159	19.267	17.44	19.765	20.315	16.742	17.236	15.276	15.728
PE(P-16:0/20:5)	0.355	1.356	1.607	0.506	0.961	0.86	0.545	1.611	1.558	0.778	0.474	0.758	1.272	0.357	1.441	0.511	0.149	0.697	0.43	0.674	1.163	1.355	0.614	0.531	1.154	1.485	0.371	0.353	0.433	0.455	N.D.	0.442	0.375	N.D.	0.436	0.359	0.385	0.387	0.475	0.369	0.486	N.D.	0.316	0.487	0.568	0.334	0.406	0.395	0.332	0.485	0.34	0.366	0.738	0.344	0.332	0.396	0.405	0.396	0.36	0.461	0.685	0.469	0.383	0.32	0.356
PE(P-16:0/22:4)	9.711	27.07	27.826	19.595	22.819	26.596	20.823	35.046	31.945	23.497	20.355	21.962	26.27	9.679	32.294	20.985	11.396	24.322	18.851	21.008	26.989	23.164	17.517	19.623	25.161	27.653	11.109	10.79	11.69	11.272	N.D.	10.972	10.407	N.D.	10.301	11.148	10.44	11.701	8.684	10.267	10.843	N.D.	11.756	11.981	10.81	12.06	10.316	10.49	8.913	12.996	10.865	10.206	12.358	10.706	12.63	11.266	11.334	11.104	11.261	10.599	10.009	9.4	10.017	9.879	8.11
PE(P-16:0/22:6)	2.409	6.375	7.145	1.965	4.387	3.558	2.346	6.828	6.796	3.363	2.237	3.441	5.937	2.413	5.701	2.573	0.611	2.832	2.031	2.802	5.195	5.902	2.921	2.257	4.205	7.154	2.436	2.076	2.691	2.372	N.D.	2.341	1.848	N.D.	2.152	2.406	2.083	2.165	3.565	2.292	3.01	N.D.	1.945	2.518	3.329	1.938	1.992	3.048	1.731	2.333	1.562	2.359	3.919	1.594	1.849	2.81	2.041	2.232	1.712	2.413	4.215	3.09	1.686	1.588	1.857
PE(P-18:0/18:1(d9))	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
PE(P-18:0/18:1)	7.328	22.533	24.645	12.346	14.393	16.377	12.959	23.68	23.699	14.817	14	14.153	20.329	7.007	21.356	13.819	5.903	15.896	12.296	10.87	19.134	21.806	11.894	13.993	14.976	23.956	8.265	11.631	11.731	11.8	N.D.	10.881	9.88	N.D.	8.74	10.423	10.264	10.337	10.739	10.221	11.986	N.D.	10.214	12.725	11.266	10.308	9.977	9.757	8.531	11.369	10.228	10.918	13.795	8.856	10.385	11.44	10.704	10.756	9.733	11.905	13.094	10.281	9.073	9.11	8.188
PE(P-18:0/18:2)	0.729	2.432	2.776	1.313	1.704	1.759	1.511	2.532	2.818	1.614	1.685	1.811	2.235	0.778	2.41	1.689	0.596	1.605	1.426	1.333	1.988	2.416	1.438	1.528	1.932	2.64	0.766	1.279	1.292	1.249	N.D.	1.215	1.081	N.D.	0.986	1.146	1.346	1.176	1.16	1.147	1.299	N.D.	1.078	1.358	1.405	1.174	1.183	1.207	0.945	1.257	1.02	1.167	1.542	0.944	1.06	1.325	1.157	1.261	1.068	1.31	1.436	1.217	1.024	0.911	0.956
PE(P-18:0/20:4)	10.301	35.879	36.06	21.526	23.918	24.093	21.968	32.647	32.886	23.768	24.478	24.651	30.703	9.52	30.724	23.305	10.284	26.934	20.004	18.866	26.436	29.913	18.57	20.553	25.939	36.107	10.83	15.627	13.514	16.04	N.D.	15.432	12.946	N.D.	14.509	12.005	13.735	14.446	13.205	12.134	14.346	N.D.	12.82	16.28	15.976	14.005	13.834	14.236	12.318	19.726	14.36	13.29	17.061	14.012	14.857	13.472	13.82	14.543	14.042	16.228	15.374	13.791	11.881	12.108	12.534
PE(P-18:0/20:5)	0.311	1.259	1.204	0.491	0.768	0.658	0.486	1.136	1.222	0.642	0.477	0.69	1.044	0.28	1.2	0.583	0.127	0.727	0.457	0.526	0.992	1.194	0.544	0.493	0.816	1.421	0.243	0.45	0.401	0.497	N.D.	0.519	0.402	N.D.	0.444	0.384	0.405	0.393	0.552	0.386	0.452	N.D.	0.481	0.47	0.572	0.473	0.399	0.571	0.356	0.504	0.401	0.404	0.769	0.4	0.487	0.424	0.447	0.46	0.373	0.51	0.624	0.529	0.377	0.341	0.396
PE(P-18:0/22:6)	1.039	3.555	4.491	1.468	2.105	2.094	1.381	3.828	3.534	2.013	1.277	1.796	3.53	1.043	3.211	1.542	0.501	1.99	1.131	1.447	3.107	3.313	1.794	1.379	2.112	4.068	1.1	1.268	1.404	1.357	N.D.	1.283	1.033	N.D.	1.357	1.078	1.205	1.07	1.788	1.223	1.331	N.D.	1.084	1.403	2.042	1.066	1.121	1.663	1.141	1.428	0.968	1.188	2.409	1.058	1.098	1.371	1.114	1.263	1.021	1.328	2.116	1.752	0.976	0.987	1.144
PE(P-18:1/20:4)	5.317	17.116	15.466	10.596	14.193	12.049	11.735	15.462	14.283	11.311	12.911	14.037	16.49	4.782	14.867	12.935	5.057	12.922	12.003	11.236	11.161	12.376	9.092	13.085	13.425	17.394	5.137	6.099	6.163	6.157	N.D.	6.213	6.56	N.D.	6.545	5.701	5.163	7.273	4.908	5.872	6.216	N.D.	5.589	6.342	5.876	5.475	5.542	5.547	4.885	8.412	6.189	5.927	6.439	6.111	6.208	6.272	6.994	5.949	6.367	5.785	6.063	5.335	6.195	5.616	4.992
PE(P-18:1/22:6)	0.72	1.918	1.952	0.768	1.491	1.087	0.904	1.646	1.876	1.019	0.937	1.218	1.907	0.613	1.549	1.077	0.259	1.046	0.743	0.9	1.389	1.635	0.874	0.963	1.316	2.223	0.674	0.578	0.766	0.693	N.D.	0.629	0.63	N.D.	0.701	0.626	0.538	0.684	0.961	0.659	0.816	N.D.	0.614	0.662	0.961	0.559	0.592	0.819	0.494	0.788	0.491	0.691	1.073	0.489	0.637	0.774	0.721	0.669	0.566	0.65	1.046	0.89	0.574	0.506	0.516
PEth(16:0_18:1)	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
PEth(18:1/18:1)	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	1.219	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	0.546	0.837	0.929	3.389	0.819	0.333	0.237	0.293	0.264	N.D.	N.D.	N.D.	0.176	0.336	0.364	N.D.	N.D.	N.D.	0.351	N.D.	N.D.	N.D.
PG(15:0/18:1(d7))	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
PG(16:0_18:1)	0.309	0.939	1.583	0.402	0.595	0.676	0.331	1.483	1.404	0.744	0.328	0.416	0.736	0.293	1.339	0.301	0.104	0.495	0.324	0.543	1.19	1.459	0.582	0.344	0.635	0.849	0.337	0.338	0.381	0.339	N.D.	0.363	0.273	N.D.	0.214	0.347	0.334	0.266	0.403	0.339	0.418	N.D.	0.252	0.41	0.302	0.313	0.341	0.305	0.2	0.282	0.263	0.373	0.444	0.264	0.254	0.387	0.265	0.294	0.218	0.374	0.46	0.316	0.228	0.199	0.181
PG(16:0_20:4)	0.004	0.007	0.007	0.005	0.008	0.005	0.006	0.009	0.009	0.008	0.005	0.006	0.009	0.002	0.009	0.003	0.002	0.006	0.005	0.007	0.009	0.01	0.006	0.005	0.005	0.006	0.003	0.002	0.003	0.002	N.D.	0.003	0.003	N.D.	0.001	0.002	0.003	0.003	0.003	0.003	0.002	N.D.	0.002	0.002	0.002	0.002	0.002	0.004	0.003	0.002	0.002	0.004	0.003	0.003	0.002	0.002	0.003	0.003	0.003	0.003	0.004	0.003	0.002	0.003	0.003
PG(16:0_22:6)	0.002	0.006	0.006	0.005	0.006	0.006	0.004	0.008	0.008	0.005	0.003	0.003	0.007	0.002	0.006	0.002	0.001	0.004	0.002	0.003	0.006	0.007	0.003	0.005	0.004	0.005	0.002	0.003	0.001	0.002	N.D.	0.001	0.002	N.D.	0.002	0.002	0.002	0.001	0.002	0.002	0.001	N.D.	0.002	0.002	0.001	0.002	0.004	0.004	0.003	0.002	0.002	0.001	0.003	0.002	0.002	0.001	0.002	0.002	0.001	0.002	0.003	0.003	0.001	0.001	0.003
PG(18:0_18:1)	0.433	1.485	2.326	0.612	0.887	0.78	0.435	1.874	1.727	0.834	0.438	0.556	1.165	0.418	1.842	0.439	0.197	0.671	0.452	0.726	1.64	2.225	0.68	0.511	0.865	1.495	0.403	0.613	0.693	0.451	N.D.	0.634	0.6	N.D.	0.424	0.47	0.418	0.568	0.991	0.533	0.783	N.D.	0.409	0.661	0.631	0.465	0.586	0.559	0.422	0.452	0.579	0.544	1	0.525	0.497	0.691	0.501	0.442	0.339	0.585	0.897	0.59	0.324	0.362	0.389
PG(18:0_20:4)	0.003	0.014	0.018	0.009	0.01	0.008	0.006	0.017	0.014	0.012	0.006	0.008	0.013	0.006	0.019	0.008	0.003	0.007	0.006	0.009	0.013	0.014	0.007	0.007	0.009	0.011	0.005	0.007	0.006	0.004	N.D.	0.005	0.006	N.D.	0.011	0.005	0.004	0.005	0.011	0.005	0.007	N.D.	0.005	0.005	0.011	0.005	0.005	0.011	0.014	0.006	0.004	0.006	0.018	0.006	0.006	0.006	0.006	0.003	0.005	0.007	0.017	0.011	0.005	0.008	0.01
PG(18:0_22:6)	0.001	0.004	0.005	0.003	0.004	0.003	0.002	0.004	0.005	0.004	0.004	0.004	0.004	0.001	0.005	0.002	0.001	0.003	0.002	0.004	0.002	0.004	0.003	0.003	0.003	0.005	0.001	0.004	0.001	0.002	N.D.	0.003	0.002	N.D.	0.008	0.001	0.003	0.003	0.016	0.002	0.003	N.D.	0.002	0.003	0.016	0.002	0.004	0.012	0.011	0.002	0.002	0.001	0.015	0.002	0.002	0.002	0.002	0.002	0.002	0.002	0.017	0.012	0.002	0.004	0.009
PG(18:1/18:1)	0.106	0.267	0.44	0.198	0.191	0.297	0.202	0.464	0.418	0.304	0.159	0.226	0.22	0.101	0.389	0.154	0.108	0.207	0.232	0.197	0.354	0.422	0.223	0.164	0.239	0.265	0.102	N.D.	0.159	0.151	N.D.	0.161	0.119	N.D.	0.096	0.15	0.125	0.108	0.158	0.141	0.165	N.D.	0.128	0.167	0.114	0.159	N.D.	0.111	0.084	0.115	0.106	0.149	0.172	0.113	0.109	0.17	0.114	0.132	0.097	0.163	0.16	0.119	0.089	0.089	0.091
PG(22:6/22:6)	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	0.051	N.D.	N.D.	N.D.	0.093	N.D.	N.D.	N.D.	N.D.	N.D.	0.07	N.D.	N.D.	0.091	0.197	N.D.	N.D.	N.D.	0.145	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	0.134	0.118	N.D.	N.D.	0.116
PI(15:0/18:1(d7))	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
PI(16:0_18:1)	1.152	3.339	4.039	1.376	2.168	2.294	1.274	4.243	3.864	2.199	1.139	1.8	2.642	1.057	3.948	1.125	0.431	1.577	1.069	1.729	3.213	4.062	1.868	1.301	2.093	3.194	1.087	0.979	1.711	1.131	N.D.	1.212	1.105	N.D.	0.803	1.268	1.038	1.043	1.259	1.411	1.65	N.D.	0.923	1.28	1.065	1.07	0.896	0.92	0.734	1.058	0.869	1.396	1.38	0.958	0.725	1.635	0.976	1.218	0.929	1.283	1.432	1.307	0.871	0.757	0.782
PI(16:0_20:4)	0.501	1.442	1.417	0.765	1.355	1.011	0.874	1.821	1.717	1.039	0.893	1.229	1.604	0.449	1.756	0.849	0.277	0.781	0.811	1.304	1.178	1.277	0.801	0.915	1.389	1.508	0.456	0.403	0.575	0.509	N.D.	0.489	0.58	N.D.	0.416	0.564	0.402	0.575	0.506	0.586	0.593	N.D.	0.399	0.461	0.397	0.494	0.406	0.474	0.481	0.588	0.515	0.508	0.678	0.522	0.467	0.596	0.54	0.514	0.444	0.482	0.666	0.617	0.522	0.518	0.469
PI(16:0_22:6)	0.049	0.146	0.115	0.037	0.114	0.095	0.056	0.18	0.166	0.083	0.041	0.08	0.132	0.036	0.154	0.046	0.009	0.059	0.056	0.09	0.092	0.11	0.076	0.049	0.136	0.16	0.031	0.035	0.048	0.043	N.D.	0.047	0.056	N.D.	0.052	0.045	0.025	0.052	0.076	0.047	0.05	N.D.	0.019	0.039	0.057	0.029	0.03	0.064	0.045	0.048	0.042	0.051	0.099	0.038	0.033	0.059	0.05	0.038	0.032	0.036	0.097	0.078	0.052	0.037	0.042
PI(18:0_18:1)	2.156	5.525	7.19	3.132	4.231	4.34	3.131	6.777	6.307	4.11	2.942	3.753	5.289	1.995	6.275	2.899	1.077	3.386	2.464	3.16	5.647	7.042	3.019	3.419	3.87	6.406	2.338	1.893	2.631	2.224	N.D.	1.862	1.967	N.D.	1.654	2.336	1.903	1.774	2.48	2.613	2.648	N.D.	1.919	2.334	2.351	2.279	1.581	2.089	1.766	2.018	1.511	2.28	2.392	1.624	1.543	2.602	1.56	2.251	1.643	2.356	2.187	2.552	1.5	1.516	1.521
PI(18:0_20:4)	4.657	13.743	11.952	8.954	10.595	10.815	9.019	13.262	13.331	10.735	8.641	11.29	11.726	4.464	12.722	9.396	4.062	9.359	8.358	10.05	10.275	12.101	8.079	10.509	10.292	13.477	4.423	4.795	6.161	5.057	N.D.	4.55	5.443	N.D.	5.057	4.799	4.862	4.93	5.554	5.557	5.901	N.D.	4.513	5.016	5.218	5.04	4.452	4.988	5.183	5.685	5.148	5.236	6.127	4.624	3.843	5.769	4.611	5.03	5.194	5.177	5.955	6.212	4.649	4.685	5.559
PI(18:0_22:6)	0.239	0.523	0.503	0.207	0.388	0.37	0.267	0.523	0.547	0.355	0.197	0.364	0.547	0.189	0.618	0.23	0.06	0.269	0.207	0.317	0.412	0.554	0.3	0.254	0.361	0.621	0.228	0.144	0.207	0.191	N.D.	0.174	0.163	N.D.	0.234	0.216	0.17	0.168	0.502	0.253	0.238	N.D.	0.151	0.203	0.383	0.192	0.141	0.428	0.234	0.223	0.11	0.234	0.491	0.122	0.129	0.214	0.152	0.206	0.159	0.194	0.514	0.448	0.135	0.177	0.258
PI(18:1/18:1)	2.211	6.437	8.665	2.335	4.436	3.977	2.385	7.438	7.419	3.955	2.292	3.469	5.792	1.941	7.116	2.237	0.656	2.923	2.048	3.291	6.069	8.188	3.301	2.6	3.651	6.788	2.067	1.951	3.117	2.301	N.D.	2.486	2.023	N.D.	1.455	2.515	2.276	1.849	2.445	2.737	3.156	N.D.	1.687	2.671	1.963	2.083	1.787	1.783	1.346	1.924	1.767	2.573	2.527	1.825	1.454	3.119	1.785	2.409	1.733	2.469	2.434	2.342	1.651	1.522	1.285
PI(20:4/20:4)	N.D.	0.004	0.003	0.004	N.D.	0.007	N.D.	0.006	N.D.	0.008	0.004	0.007	0.002	N.D.	0.004	0.004	N.D.	N.D.	0.006	0.002	0.004	N.D.	0.003	0.008	N.D.	0.007	0.002	0.003	0.004	0.005	N.D.	0.004	0.003	N.D.	0.002	0.002	0.003	0.004	0.001	0.008	0.005	N.D.	0.007	0.004	0.004	0.005	0.004	0.007	0.005	0.008	0.006	0.007	0.006	0.006	0.003	0.004	N.D.	0.004	0.003	0.007	0.007	0.004	0.005	0.004	0.008
PS(15:0/18:1(d7))	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
PS(16:0_18:1)	1.929	6.457	8.449	1.893	3.75	3.177	2.288	6.779	5.857	3.541	2.698	3.073	5.873	1.768	6.194	2.464	0.52	2.665	2.831	2.903	7.095	7.6	2.921	2.456	4.13	6.343	1.757	2.01	2.564	1.975	N.D.	2.371	2.379	N.D.	1.522	2.306	1.923	2.381	2.471	2.031	2.655	N.D.	1.679	2.438	1.814	1.838	1.963	1.517	1.679	1.625	2.092	1.993	2.662	2.113	2.028	2.66	2.064	1.902	1.639	2.298	2.547	1.842	1.714	1.428	1.282
PS(16:0_20:4)	0.033	0.115	0.186	0.058	0.092	0.091	0.078	0.152	0.137	0.096	0.079	0.078	0.122	0.035	0.115	0.094	0.026	0.093	0.105	0.089	0.174	0.132	0.083	0.076	0.105	0.12	0.038	0.029	0.054	0.053	N.D.	0.037	0.058	N.D.	0.021	0.041	0.04	0.038	0.035	0.029	0.035	N.D.	0.03	0.051	0.035	0.04	0.046	0.033	0.03	0.029	0.035	0.029	0.051	0.035	0.041	0.046	0.017	0.031	0.033	0.041	0.047	0.03	0.025	0.028	0.031
PS(16:0_22:6)	0.048	0.133	0.17	0.034	0.073	0.073	0.043	0.128	0.139	0.066	0.039	0.052	0.137	0.021	0.136	0.047	0.014	0.033	0.049	0.067	0.159	0.155	0.058	0.047	0.09	0.118	0.044	0.042	0.043	0.026	N.D.	0.032	0.047	N.D.	0.04	0.043	0.025	0.045	0.06	0.055	0.05	N.D.	0.02	0.032	0.045	0.023	0.047	0.042	0.044	0.025	0.033	0.034	0.076	0.043	0.031	0.05	0.041	0.031	0.025	0.033	0.084	0.05	0.023	0.034	0.047
PS(18:0_18:1)	18.573	57.908	76.426	27.089	34.009	38.041	23.644	65.02	58.631	39.834	26.841	30.274	53.22	17.529	61.713	29.179	10.35	34.053	25.686	26.374	60.642	72.519	32.497	27.794	36.803	58.742	19.135	17.623	20.178	18.14	N.D.	19.351	19.123	N.D.	14.293	19.77	18.364	17.177	21.637	19.319	22.172	N.D.	17.185	19.971	17.728	18.838	17.02	17.408	14.112	16.009	13.873	18.598	22.227	14.638	16.514	22.975	16.367	18.216	13.628	17.775	19.872	17.254	14.05	11.467	11.724
PS(18:0_20:4)	1.001	2.595	3.655	2.036	2.032	2.432	1.667	3.299	3.025	2.378	1.952	1.831	2.622	0.873	3.084	1.966	0.981	2.196	1.998	1.688	3.281	3.18	1.912	1.789	2.138	2.652	0.973	1.024	1.171	0.987	N.D.	1.092	1.07	N.D.	0.788	1.008	0.984	1.023	0.955	0.988	1.129	N.D.	0.904	1.098	0.797	0.898	0.977	0.802	0.805	0.825	1.044	0.95	1.053	0.876	0.935	1.21	0.942	0.993	0.855	1.036	1.094	0.815	0.724	0.662	0.603
PS(18:0_22:6)	3.066	8.763	11.796	2.954	6.04	4.884	2.966	9.922	9.277	4.986	3.155	4.263	8.005	2.872	8.076	3.417	0.713	3.768	2.968	4.383	9.576	9.89	4.294	3.462	6.166	9.714	3.177	2.262	3.589	2.734	N.D.	2.916	2.851	N.D.	2.685	3.06	2.494	2.713	4.59	2.723	3.711	N.D.	2.159	3.167	3.718	2.475	2.306	3.123	2.155	2.211	2.167	3.018	4.712	2.216	2.295	3.811	2.4	2.518	2.096	3.026	4.151	3.657	1.944	1.754	1.989
PS(18:1/18:1)	2.214	6.112	9.955	2.696	3.789	4.502	2.48	8.11	6.927	4.518	2.869	3	5.926	2.138	6.604	2.829	0.94	3.489	2.617	2.915	7.068	9.055	3.629	2.847	4.367	6.941	2.059	2.047	2.548	2.118	N.D.	2.354	2.201	N.D.	1.43	2.354	1.998	2.136	2.205	2.392	2.745	N.D.	1.859	2.458	1.902	1.891	1.84	1.566	1.287	1.51	1.719	2.299	2.35	1.625	1.752	2.864	1.859	1.929	1.671	2.141	2.418	1.781	1.627	1.3	1.158
PS(22:6/22:6)	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
Palmitic acid	6.579	5.17	3.575	4.814	4.208	3.219	3.375	2.732	3.192	3.082	3.541	5.195	3.747	5.764	2.848	4.099	3.448	3.176	3.919	4.23	2.716	5.518	5.031	4.376	3.051	4.5	5.948	7.849	5.576	5.346	N.D.	3.393	5.842	N.D.	4.693	6.692	7.057	4.258	4.86	7.651	4.447	N.D.	7.003	4.219	12.95	12.074	6.12	5.923	4.407	5.136	3.485	6.943	6.553	3.609	5.255	4.169	5.23	6.144	6.44	5.856	3.736	6.597	3.463	5.211	3.787
Palmitoleic acid	0.139	0.207	0.42	0.198	0.191	0.322	0.197	0.25	0.341	0.072	0.266	0.214	0.227	N.D.	0.42	0.216	0.239	0.204	0.309	0.198	0.282	0.166	0.352	N.D.	0.279	0.205	N.D.	0.18	0.207	0.187	N.D.	0.241	0.191	N.D.	0.097	0.197	0.144	0.216	0.42	0.221	0.457	N.D.	0.306	0.265	0.328	0.275	0.304	0.177	0.334	0.118	0.245	0.213	0.397	0.217	0.15	0.282	0.274	0.155	1.489	0.233	0.255	0.092	0.232	0.167	0.225
Stearic acid	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.	N.D.
MS_METABOLITE_DATA_END
#METABOLITES
METABOLITES_START
metabolite_name	Expected RT	MS1_mz	MS2_mz
3-O-SulfoGalCer(d18:1/16:0)	4.45	778.5	97
3-O-SulfoGalCer(d18:1/18:0(2OH)	4.87	822.6	97
3-O-SulfoGalCer(d18:1/18:0(d3))	5.06	809.6	97
3-O-SulfoGalCer(d18:1/18:0)	4.96	806.6	97
3-O-SulfoGalCer(d18:1/24:0(2OH))	6.14	906.7	97
3-O-SulfoGalCer(d18:1/24:0)	6.19	890.7	97
3-O-SulfoGalCer(d18:1/24:1(2OH))	5.73	904.7	97
3-O-SulfoGalCer(d18:1/24:1)	5.79	888.7	97
Arachidonic acid	2.33	303.2	303.2
Arachidonic acid-d8	2.3	311.3	311.3
Arachidonic acid-d8_MRM	2.3	311.3	267.1
BMP(14:0/14:0)	3.69	665.3	227.2
BMP(16:0_18:1)	4.8	747.5	255.4
BMP(16:0_20:4)	4.13	769.5	255.4
BMP(16:0_22:6)	4.2	795.5	255.4
BMP(16:1/16:1)	3.79	717.5	253.1
BMP(18:0_18:1)	5.25	775.5	281.4
BMP(18:0_20:4)	4.69	797.5	283.4
BMP(18:0_22:6)	4.7	823.5	283.4
BMP(18:1/18:1)	4.84	773.5	281.3
BMP(20:4/20:4)	3.69	817.5	303.3
BMP(22:6/22:6)	3.45	865.5	327.3
Cholesterol sulfate	3.08	465.3	96.7
CL(14:0/14:0/14:0/14:0)	7.17	619.5	227.2
CL(72:6/18:2)	7.48	725.7	279.2
CL(72:7/18:2)	7.24	724.7	279.2
CL(72:8-2(OOH)/18:2)	6.49	755.7	279.2
CL(72:8/18:2)	7.26	723.7	279.3
CL(74:9/18:2)	7.29	736.7	279.2
Docosahexaenoic acid	2.14	327.2	229.1
Eicosapentaenoic acid	1.97	301.3	257.1
FAHFA(18:1/9-O-18:0)	6.2	563.6	281
GD1a/b(d36:1)	4.54	917.5	290.1
GD3(d34:1)	4.1	720.9	290.1
GD3(d36:1)	4.65	734.9	290.1
GM3(d18:1/18:0(d5))	5.03	1184.8	290.1
GM3(d34:1)	4.54	1151.7	290.1
GM3(d36:1)	5.05	1179.8	290.1
GQ1b(d36:1)	4.13	1208.6	290.1
Hemi-BMP(14:0/14:0)_14:0	6.2	875.5	227.3
Hemi-BMP(18:1/18:1)_16:0	7.1	1011.7	281.3
Hemi-BMP(18:1/18:1)_18:0	7.2	1039.7	281.3
Hemi-BMP(18:1/18:1)_18:1	7.1	1037.7	281.3
Hemi-BMP(20:4/20:4)_16:0	6.4	1056.8	303.3
Hemi-BMP(20:4/20:4)_18:0	6.6	1185.8	303.3
Hemi-BMP(20:4/20:4)_18:1	6.4	1183.8	303.3
Hemi-BMP(20:4/20:4)_20:4	6.2	1104.8	303.3
Hemi-BMP(22:6/22:6)_16:0	6.2	1103.7	327.3
Hemi-BMP(22:6/22:6)_18:0	6.5	1131.7	327.3
Hemi-BMP(22:6/22:6)_18:1	6.2	1129.7	327.3
Hemi-BMP(22:6/22:6)_22:6	5.6	1175.7	327.3
Linoleic acid	2.46	279.2	279.2
Linolenic acid	2.08	277.2	277.2
LPE(16:0)	1.97	452.2	255.3
LPE(18:0)	2.61	480.3	283.3
LPE(18:1(d7))	2	485.3	288.3
LPG(16:0)	1.65	483.3	255.3
LPG(18:0)	2.11	511.3	283.3
LPG(18:1)	1.64	509.3	281.3
LPG(20:4)	1.29	531.3	303.3
LPG(22:6)	1.28	555.3	327.3
LPI(16:0)	1.6	571.3	241.1
LPI(18:0)	2.12	599.3	241.1
Oleic acid	2.96	281.2	281.2
PA(15:0/18:1(d7))	5.09	666.5	241.3
PA(16:0_18:1)	5.45	673.5	255.3
PA(18:0_18:1)	5.84	701.5	283.3
PA(18:0_20:4)	5.42	723.5	283.3
PA(18:0_22:6)	5.35	747.5	283.3
PA(18:1/18:1)	5.36	699.5	281.3
Palmitic acid	2.98	255.1	255.1
Palmitoleic acid	2.35	253.1	253.1
PE(15:0/18:1(d7))	5.49	709.6	241.3
PE(O-16:0/20:4)	5.48	724.5	303.2
PE(O-16:0/22:6)	5.38	748.5	327.2
PE(O-18:0/20:4)	5.97	752.6	303.2
PE(O-18:0/22:6)	5.87	776.6	327.2
PE(P-16:0/20:4)	5.48	722.6	303.3
PE(P-16:0/20:5)	5.11	720.6	301.3
PE(P-16:0/22:4)	5.83	750.6	331.3
PE(P-16:0/22:6)	5.29	746.6	327.3
PE(P-18:0/18:1)	6.4	728.6	281.3
PE(P-18:0/18:2)	6.08	726.6	279.2
PE(P-18:0/20:4)	5.96	750.6	303.3
PE(P-18:0/20:5)	5.61	748.6	301.3
PE(P-18:0/22:6)	5.79	774.6	327.3
PE(P-18:1/20:4)	5.48	748.5	303.3
PE(P-18:1/22:6)	5.29	772.5	327.3
PEth(16:0_18:1)	5.4	772.5	255.1
PEth(18:1/18:1)	5.4	773.6	281.2
PG(15:0/18:1(d7))	4.87	740.6	241.3
PG(16:0_18:1)	5.13	747.5	255.3
PG(16:0_20:4)	4.61	769.5	255.3
PG(16:0_22:6)	4.28	795.5	255.3
PG(18:0_18:1)	5.6	775.5	281.3
PG(18:0_20:4)	5.14	797.5	283.3
PG(18:0_22:6)	4.79	823.5	283.3
PG(18:1/18:1)	5.14	773.4	281.4
PI(15:0/18:1(d7))	4.87	828.6	241.3
PI(16:0_18:1)	5.04	835.6	255.3
PI(16:0_20:4)	4.61	857.6	255.3
PI(16:0_22:6)	4.43	881.6	255.3
PI(18:0_18:1)	5.51	863.6	283.3
PI(18:0_20:4)	5.12	885.6	283.3
PI(18:0_22:6)	4.97	909.6	283.3
PI(18:1/18:1)	5.04	861.6	281.3
PI(20:4/20:4)	3.96	905.6	303.3
PS(15:0/18:1(d7))	4.94	753.6	241.3
PS(16:0_18:1)	5.19	760.6	255.3
PS(16:0_20:4)	4.68	782.6	255.3
PS(16:0_22:6)	4.5	806.6	255.3
PS(18:0_18:1)	5.66	788.6	283.3
PS(18:0_20:4)	5.25	810.6	283.3
PS(18:0_22:6)	5.02	834.6	283.3
PS(18:1/18:1)	5.19	786.6	281.3
PS(22:6/22:6)	3.66	878.5	327.3
Stearic acid	3.6	283.2	283.2
PE(P-18:0/18:1(d9))	6.4	737.6	290.2
PG(22:6/22:6)	3.65	865.5	327.3
METABOLITES_END
#END