Summary of Study ST000876
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000607. The data can be accessed directly via it's Project DOI: 10.21228/M86Q34 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Study ID | ST000876 |
| Study Title | Human serum for a patient with neuropathy being treated with L-serine. |
| Study Type | drug dosage |
| Study Summary | Oral serine dosing over 52 week study period |
| Institute | University of Helsinki |
| Department | Molecular Neurology |
| Last Name | Ylikallio |
| First Name | Emil |
| Address | Hartmaninkatu 8, 00290 Helsinki, Finland |
| emil.ylikallio@helsinki.fi | |
| Phone | None |
| Submit Date | 2017-09-05 |
| Publications | Clinical and metabolic consequences of L-serine supplementation in hereditary sensory and autonomic neuropathy type 1C, Cold Spring Harbor Molecular Case Studies |
| Analysis Type Detail | MS(Dir. Inf.) |
| Release Date | 2017-10-11 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Project:
| Project ID: | PR000607 |
| Project DOI: | doi: 10.21228/M86Q34 |
| Project Title: | Human serum for a patient with neuropathy being treated with L-serine. |
| Project Summary: | Human serum for a patient with neuropathy being treated with L-serine. |
| Institute: | University of Helsinki |
| Last Name: | Ylikallio |
| First Name: | Emil |
| Address: | Haartmaninkatu 8, 00290, Helsinki, Finland |
| Email: | emil.ylikallio@helsinki.fi |
| Phone: | None |
Subject:
| Subject ID: | SU000903 |
| Subject Type: | Human |
| Subject Species: | Homo sapiens |
| Taxonomy ID: | 9606 |
| Species Group: | Mammals |
Factors:
Subject type: Human; Subject species: Homo sapiens (Factor headings shown in green)
| mb_sample_id | local_sample_id | L-serine (mg/kg/day) | time point (weeks) |
|---|---|---|---|
| SA049379 | week6_100 | 100 | 6 |
| SA049380 | week52_200 | 200 | 52 |
| SA049381 | week9_200 | 200 | 9 |
| SA049382 | week12_300 | 300 | 12 |
| SA049383 | weel15_400 | 400 | 15 |
| SA049384 | week18_400 | 400 | 18 |
| SA049385 | week21_400 | 400 | 21 |
| SA049386 | week30_400 | 400 | 30 |
| SA049387 | week38_400 | 400 | 38 |
| SA049388 | week44_400 | 400 | 44 |
| SA049389 | week3_50 | 50 | 3 |
| SA049377 | week0_0 | - | - |
| SA049378 | week-1_0 | - | - |
| Showing results 1 to 13 of 13 |
Collection:
| Collection ID: | CO000897 |
| Collection Summary: | None |
| Sample Type: | Blood |
| Blood Serum Or Plasma: | Serum |
Treatment:
| Treatment ID: | TR000917 |
| Treatment Summary: | Oral L-serine |
| Treatment Compound: | L-serine |
| Treatment Route: | Oral |
| Treatment Dose: | 0-400 mg/kg/day |
| Treatment Doseduration: | 52 weeks |
Sample Preparation:
| Sampleprep ID: | SP000910 |
| Sampleprep Summary: | None |
Combined analysis:
| Analysis ID | AN001413 |
|---|---|
| Chromatography ID | CH000988 |
| MS ID | MS001304 |
| Analysis type | MS |
| Chromatography type | None (Direct infusion) |
| Chromatography system | None |
| Column | none |
| MS Type | ESI |
| MS instrument type | Triple quadrupole |
| MS instrument name | Waters Xevo-TQ-S |
| Ion Mode | POSITIVE |
| Units | µM |
Chromatography:
| Chromatography ID: | CH000988 |
| Instrument Name: | None |
| Column Name: | none |
| Chromatography Type: | None (Direct infusion) |
MS:
| MS ID: | MS001304 |
| Analysis ID: | AN001413 |
| Instrument Name: | Waters Xevo-TQ-S |
| Instrument Type: | Triple quadrupole |
| MS Type: | ESI |
| Ion Mode: | POSITIVE |
