Summary of Study ST002996

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001866. The data can be accessed directly via it's Project DOI: 10.21228/M8HM8S This work is supported by NIH grant, U2C- DK119886.

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This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST002996
Study TitleTissue Lipidomic Profiling for Detection of Non-Small Cell Lung Cancer
Study SummaryUPLC-HRMS analysis was performed on AC and SCC patients. OPLSDA classfication was performed on tumor vs. ANT and DNT samples. Panels of discriminant features were identified. The biomarkers identified in discovery set samples for each binary classification were confirmed by using a set of validation samples, which were run separately. Additionally, paired analysis showed the abundance of discriminant compounds has significant altered in tumor tissues compared to corresponding DNT and ANT samples, reflecting the lipid characteristics related to tumor in situ and cancer cell signaling.
Institute
OUC
DepartmentDepartment of Medicine and Pharmacy
LaboratoryAnalytical chemistry
Last NameZhang
First NameJie
AddressNo. 5 Yushan Road, Qingdao, Shandong, China
Emailzhangjieqau@163.com
Phone17806277823
Submit Date2023-11-16
Raw Data AvailableYes
Raw Data File Type(s)raw(Thermo)
Analysis Type DetailLC-MS
Release Date2023-12-27
Release Version1
Jie Zhang Jie Zhang
https://dx.doi.org/10.21228/M8HM8S
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Combined analysis:

Analysis ID AN004921
Analysis type MS
Chromatography type Reversed phase
Chromatography system Agilent 1290 Infinity
Column Waters ACQUITY UPLC BEH C18 (50 x 2.1mm,1.7um)
MS Type ESI
MS instrument type Orbitrap
MS instrument name Thermo LTQ XL
Ion Mode POSITIVE
Units Peak area
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