Summary of Study ST000770

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000556. The data can be accessed directly via it's Project DOI: 10.21228/M8ST09 This work is supported by NIH grant, U2C- DK119886.

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Study IDST000770
Study TitleIntranasal oxytocin in lean and obese men
Study TypeMS analysis
Study SummaryFrom Lawson et al., Obesity 2015 (PMID: 25865294). Methods: A randomized, placebo-controlled crossover study of single-dose intranasal oxytocin (24 IU) in 25 fasting healthy men was performed. After oxytocin/placebo, subjects selected breakfast from a menu and were given double portions. Caloric content of food consumed was measured. Visual analog scales were used to assess appetite, and blood was drawn for appetite-regulating hormones, insulin, and glucose before and after oxytocin/placebo. Indirect calorimetry assessed resting energy expenditure (REE) and substrate utilization. Here, T0 refers to immediately before OXT or Placebo was administered (fasting), and T55 refers to 55 minutes post-administration (fasting, immediately pre-meal).
Institute
University of Michigan
DepartmentBiomedical Research Core Facilities
LaboratoryMetabolomics core
Last NameKachman
First NameMaureen
Address6300 Brehm Tower, 1000 Wall Street, Ann Arbor, MI 48105-5714
Emailmkachman@med.umich.edu
Phone(734) 232-8175
Submit Date2017-06-19
Num Groups8
Total Subjects25
Raw Data AvailableYes
Raw Data File Type(s)d
Analysis Type DetailLC-MS
Release Date2017-12-06
Release Version1
Maureen Kachman Maureen Kachman
https://dx.doi.org/10.21228/M8ST09
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Combined analysis:

Analysis ID AN001217
Chromatography ID CH000853
MS ID MS001112
Analysis type MS
Chromatography type Reversed phase
Chromatography system Agilent
Column Waters Xbridge BEH C18 (50 x 1mm,3.5um)
MS Type ESI
MS instrument type Triple quadrupole
MS instrument name Agilent 6490A QQQ
Ion Mode POSITIVE
Units uM
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