Summary of Study ST001040
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000696. The data can be accessed directly via it's Project DOI: 10.21228/M8Q96S This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST001040 |
| Study Title | Maternal gut microbiome, pregnancy exposure to environmental contaminants, and child health outcomes: A pilot study exploring potential effect modifications by diet |
| Study Type | CHEAR Pilot Study |
| Study Summary | Using specimens collected as part of a pilot RCT of a diet intervention in pregnancy, we propose to ship our time 2 blood and urine samples (collected post-diet intervention or usual care at 36 weeks gestation) to: 1) Assess biomarker confirmation of the diet intervention effect via: (a) carotenoids and/or other antioxidants (which have been shown to be a good marker of fruit and vegetable intake); and (b) untargeted metabolomics. 2) Assess pregnancy exposure to metals and/or other environmental contaminants. 3) Combine the biomarker data proposed here in aims 1 and 2 with the data being analyzed at MSU (diet survey data and butyrate composition of stool) to explore potential bi-directional effects on gut microbiome, environmental contaminants, and dietary factors. |
| Institute | Icahn School of Medicine at Mount Sinai |
| Department | Department of Environmental Medicine and Public Health |
| Laboratory | Mount Sinai CHEAR Untargeted Laboratory Hub |
| Last Name | Walker |
| First Name | Douglas |
| Address | Atran Building RM AB3-39, 1428 Madison Ave |
| douglas.walker@mssm.edu | |
| Phone | 212-241-4392 |
| Submit Date | 2018-08-21 |
| Total Subjects | 26 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | d |
| Chear Study | Yes |
| Analysis Type Detail | LC-MS |
| Release Date | 2024-12-31 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Combined analysis:
| Analysis ID | AN001702 | AN001703 |
|---|---|---|
| Chromatography ID | CH001200 | CH001201 |
| MS ID | MS001576 | MS001577 |
| Analysis type | MS | MS |
| Chromatography type | HILIC | Reversed phase |
| Chromatography system | Agilent 1290 Infinity II | Agilent 1290 Infinity II |
| Column | SeQuant ZIC-pHILIC (100 x 2.1mm,3.5um) | Agilent Zorbax Eclipse Plus C18 (50 x 2.1mm, 1.8 um) |
| MS Type | ESI | ESI |
| MS instrument type | QTOF | QTOF |
| MS instrument name | Agilent 6550 QTOF | Agilent 6550 QTOF |
| Ion Mode | POSITIVE | NEGATIVE |
| Units | Peak Intensity | Peak Intensity |
