Summary of Study ST002590

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001020. The data can be accessed directly via it's Project DOI: 10.21228/M8V97D This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

Study ID	ST002590
Study Title	MoTrPAC: Endurance exercise training study in young adult rats, Tissue:Hippocampus - Targeted Oxylipins
Study Summary	The goal of the endurance exercise training study in young adult rats (internal code: PASS1B-06) was to perform exercise training studies in adult (6 month) F344 rats, and from these rats collect as many tissues as feasible in order to provide high quality samples for detailed analysis by chemical analysis sites. Tissues were collected from 10-12 rats sedentary control rats concurrent with the collection of the 8-week training groups. The 8-week training group and controls were from the same cohort and same age at euthanasia (either 8). For the older age group, an additional set of controls (n=5-6) were collected with the 1-2 week training group. Rats were either sedentary or underwent an exercise training program. Rats were exercised on the rodent treadmill 5 days per week using a progressive training protocol designed to exercise the rats at approximately 70% of VO2max as outlined in the Table on the next page. Training was performed no earlier than 10:00 am and no later than 5:00 pm over 5 consecutive days per week. Training was initiated with the treadmill set at 70% of VO2 max (see tables) and 5 degrees grade for 20 minutes. The duration of exercise was increased by one minute each day until day 31 of training (start of week 7), when a duration of 50 min was reached. Speed and grade of each training session increased in larger increments due to treadmill parameters. The highest intensity and duration of training began on day 31. This intensity was maintained for the final 10 days of the protocol to ensure steady state had been achieved. If any rats were unable to perform at least 4 days of training per week they were removed from the study and euthanized. It is important to note that the starting treadmill speed varied depending on the sex and age of the rat. The initial and maximum speeds were based on VO2max measurements obtained during the pre-training testing of the compliant rats. Rats assigned to the control group followed a schedule similar to the training group. They were placed in one lane on the treadmill for 15 minutes/day, 5 days per week. The treadmill was set at 0 m/min at an incline that corresponded to the incline being used by the training group.
Institute	Emory University
Department	Biochemistry
Laboratory	Integrated Lipidomics and Metabolomics Core
Last Name	Ortlund
First Name	Eric
Address	1510 Clifton Rd. NE, Room G235, Atlanta, GA 30322
Email	eortlun@emory.edu
Phone	(404) 727-5014
Submit Date	2023-04-25
Raw Data Available	Yes
Raw Data File Type(s)	TBD
Analysis Type Detail	LC-MS
Release Date	2023-10-06
Release Version	1

Select appropriate tab below to view additional metadata details:

Factors:

Subject type: Mammal; Subject species: Rattus norvegicus (Factor headings shown in green)

mb_sample_id	local_sample_id	Group	Timepoint	Sex
SA259383	90265015208	Control	8 weeks of training or control time	Female
SA259384	90266015208	Control	8 weeks of training or control time	Female
SA259385	90248015208	Control	8 weeks of training or control time	Female
SA259386	90252015208	Control	8 weeks of training or control time	Female
SA259387	90245015208	Control	8 weeks of training or control time	Female
SA259388	90217015208	Control	8 weeks of training or control time	Male
SA259389	90237015208	Control	8 weeks of training or control time	Male
SA259390	90232015208	Control	8 weeks of training or control time	Male
SA259391	90239015208	Control	8 weeks of training or control time	Male
SA259392	90229015208	Control	8 weeks of training or control time	Male
SA259393	QC_blank_7	QC-Blank	0 hour	-	-
SA259394	QC_blank_61	QC-Blank	0 hour	-	-
SA259395	QC_blank_63	QC-Blank	0 hour	-	-
SA259396	QC_blank_6	QC-Blank	0 hour	-	-
SA259397	QC_blank_5	QC-Blank	0 hour	-	-
SA259398	QC_blank_51	QC-Blank	0 hour	-	-
SA259399	QC_blank_4	QC-Blank	0 hour	-	-
SA259400	QC_blank_64	QC-Blank	0 hour	-	-
SA259401	QC_blank_62	QC-Blank	0 hour	-	-
SA259402	QC_blank_73	QC-Blank	0 hour	-	-
SA259403	QC_blank_72	QC-Blank	0 hour	-	-
SA259404	QC_Standard_69	QC-ExternalStandard	0 hour	-	-
SA259405	QC_Standard_70	QC-ExternalStandard	0 hour	-	-
SA259406	QC_Standard_71	QC-ExternalStandard	0 hour	-	-
SA259407	QC_Standard_68	QC-ExternalStandard	0 hour	-	-
SA259408	QC_Standard_66	QC-ExternalStandard	0 hour	-	-
SA259409	QC_Standard_65	QC-ExternalStandard	0 hour	-	-
SA259410	QC_Standard_67	QC-ExternalStandard	0 hour	-	-
SA259411	QC_40	QC-Pooled	0 hour	-	-
SA259412	QC_18	QC-Pooled	0 hour	-	-
SA259413	QC_29	QC-Pooled	0 hour	-	-
SA259414	QC_prerun_3	QC-PreRun	0 hour	-	-
SA259415	QC_prerun_1	QC-PreRun	0 hour	-	-
SA259416	QC_prerun_2	QC-PreRun	0 hour	-	-
SA259417	90571015208	Training	1 week of training or control time	Female
SA259418	90560015208	Training	1 week of training or control time	Female
SA259419	90564015208	Training	1 week of training or control time	Female
SA259420	90567015208	Training	1 week of training or control time	Female
SA259421	90559015208	Training	1 week of training or control time	Female
SA259422	90422015208	Training	1 week of training or control time	Male
SA259423	90430015208	Training	1 week of training or control time	Male
SA259424	90426015208	Training	1 week of training or control time	Male
SA259425	90421015208	Training	1 week of training or control time	Male
SA259426	90423015208	Training	1 week of training or control time	Male
SA259427	90581015208	Training	2 weeks of training	Female
SA259428	90585015208	Training	2 weeks of training	Female
SA259429	90576015208	Training	2 weeks of training	Female
SA259430	90587015208	Training	2 weeks of training	Female
SA259431	90578015208	Training	2 weeks of training	Female
SA259432	90441015208	Training	2 weeks of training	Male
SA259433	90449015208	Training	2 weeks of training	Male
SA259434	90450015208	Training	2 weeks of training	Male
SA259435	90439015208	Training	2 weeks of training	Male
SA259436	90444015208	Training	2 weeks of training	Male
SA259437	90416015208	Training	4 weeks of training	Female
SA259438	90412015208	Training	4 weeks of training	Female
SA259439	90420015208	Training	4 weeks of training	Female
SA259440	90410015208	Training	4 weeks of training	Female
SA259441	90280015208	Training	4 weeks of training	Male
SA259442	90289015208	Training	4 weeks of training	Male
SA259443	90281015208	Training	4 weeks of training	Male
SA259444	90292015208	Training	4 weeks of training	Male
SA259445	90283015208	Training	4 weeks of training	Male
SA259446	90258015208	Training	8 weeks of training or control time	Female
SA259447	90251015208	Training	8 weeks of training or control time	Female
SA259448	90259015208	Training	8 weeks of training or control time	Female
SA259449	90254015208	Training	8 weeks of training or control time	Female
SA259450	90267015208	Training	8 weeks of training or control time	Female
SA259451	90218015208	Training	8 weeks of training or control time	Male
SA259452	90223015208	Training	8 weeks of training or control time	Male
SA259453	90225015208	Training	8 weeks of training or control time	Male
SA259454	90227015208	Training	8 weeks of training or control time	Male
SA259455	90222015208	Training	8 weeks of training or control time	Male

Showing results 1 to 73 of 73

Showing results 1 to 73 of 73