Summary of Study ST002616

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001020. The data can be accessed directly via it's Project DOI: 10.21228/M8V97D This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

Study ID	ST002616
Study Title	MoTrPAC: Endurance exercise training study in young adult rats, Tissue:Liver - Targeted Oxylipins
Study Summary	The goal of the endurance exercise training study in young adult rats (internal code: PASS1B-06) was to perform exercise training studies in adult (6 month) F344 rats, and from these rats collect as many tissues as feasible in order to provide high quality samples for detailed analysis by chemical analysis sites. Tissues were collected from 10-12 rats sedentary control rats concurrent with the collection of the 8-week training groups. The 8-week training group and controls were from the same cohort and same age at euthanasia (either 8). For the older age group, an additional set of controls (n=5-6) were collected with the 1-2 week training group. Rats were either sedentary or underwent an exercise training program. Rats were exercised on the rodent treadmill 5 days per week using a progressive training protocol designed to exercise the rats at approximately 70% of VO2max as outlined in the Table on the next page. Training was performed no earlier than 10:00 am and no later than 5:00 pm over 5 consecutive days per week. Training was initiated with the treadmill set at 70% of VO2 max (see tables) and 5 degrees grade for 20 minutes. The duration of exercise was increased by one minute each day until day 31 of training (start of week 7), when a duration of 50 min was reached. Speed and grade of each training session increased in larger increments due to treadmill parameters. The highest intensity and duration of training began on day 31. This intensity was maintained for the final 10 days of the protocol to ensure steady state had been achieved. If any rats were unable to perform at least 4 days of training per week they were removed from the study and euthanized. It is important to note that the starting treadmill speed varied depending on the sex and age of the rat. The initial and maximum speeds were based on VO2max measurements obtained during the pre-training testing of the compliant rats. Rats assigned to the control group followed a schedule similar to the training group. They were placed in one lane on the treadmill for 15 minutes/day, 5 days per week. The treadmill was set at 0 m/min at an incline that corresponded to the incline being used by the training group.
Institute	Emory University
Department	Biochemistry
Laboratory	Integrated Lipidomics and Metabolomics Core
Last Name	Ortlund
First Name	Eric
Address	1510 Clifton Rd. NE, Room G235, Atlanta, GA 30322
Email	eortlun@emory.edu
Phone	(404) 727-5014
Submit Date	2023-04-28
Raw Data Available	Yes
Raw Data File Type(s)	TBD
Analysis Type Detail	LC-MS
Release Date	2023-10-06
Release Version	1

Select appropriate tab below to view additional metadata details:

Factors:

Subject type: Mammal; Subject species: Rattus norvegicus (Factor headings shown in green)

mb_sample_id	local_sample_id	Group	Timepoint	Sex
SA261027	90266016810	Control	8 weeks of training or control time	Female
SA261028	90252016810	Control	8 weeks of training or control time	Female
SA261029	90248016810	Control	8 weeks of training or control time	Female
SA261030	90265016810	Control	8 weeks of training or control time	Female
SA261031	90245016810	Control	8 weeks of training or control time	Female
SA261032	90229016810	Control	8 weeks of training or control time	Male
SA261033	90237016810	Control	8 weeks of training or control time	Male
SA261034	90217016810	Control	8 weeks of training or control time	Male
SA261035	90239016810	Control	8 weeks of training or control time	Male
SA261036	90232016810	Control	8 weeks of training or control time	Male
SA261037	QC_blank_79	QC-Blank	0 hour	-
SA261038	QC_blank_69	QC-Blank	0 hour	-
SA261039	QC_blank_4	QC-Blank	0 hour	-
SA261040	QC_blank_78	QC-Blank	0 hour	-
SA261041	QC_blank_68	QC-Blank	0 hour	-
SA261042	QC_blank_66	QC-Blank	0 hour	-
SA261043	QC_Standard_71	QC-ExternalStandard	0 hour	-
SA261044	QC_Standard_75	QC-ExternalStandard	0 hour	-
SA261045	QC_Standard_76	QC-ExternalStandard	0 hour	-
SA261046	QC_Standard_77	QC-ExternalStandard	0 hour	-
SA261047	QC_Standard_74	QC-ExternalStandard	0 hour	-
SA261048	QC_Standard_73	QC-ExternalStandard	0 hour	-
SA261049	QC_Standard_70	QC-ExternalStandard	0 hour	-
SA261050	QC_Standard_72	QC-ExternalStandard	0 hour	-
SA261051	QC_62	QC-Pooled	0 hour	-
SA261052	QC_51	QC-Pooled	0 hour	-
SA261053	QC_67	QC-Pooled	0 hour	-
SA261054	QC_40	QC-Pooled	0 hour	-
SA261055	QC_18	QC-Pooled	0 hour	-
SA261056	QC_7	QC-Pooled	0 hour	-
SA261057	QC_29	QC-Pooled	0 hour	-
SA261058	QC_prerun_2	QC-PreRun	0 hour	-
SA261059	QC_prerun_1	QC-PreRun	0 hour	-
SA261060	QC_prerun_3	QC-PreRun	0 hour	-
SA261061	QC_SRM	QC-Reference	0 hour	-
SA261062	G_QC_1_63	QC-Reference	0 hour	-
SA261063	G_QC_1_5	QC-Reference	0 hour	-
SA261064	G_QC_2_6	QC-Reference	0 hour	-
SA261065	G_QC_2_64	QC-Reference	0 hour	-
SA261066	90560016810	Training	1 week of training or control time	Female
SA261067	90559016810	Training	1 week of training or control time	Female
SA261068	90571016810	Training	1 week of training or control time	Female
SA261069	90564016810	Training	1 week of training or control time	Female
SA261070	90567016810	Training	1 week of training or control time	Female
SA261071	90422016810	Training	1 week of training or control time	Male
SA261072	90430016810	Training	1 week of training or control time	Male
SA261073	90423016810	Training	1 week of training or control time	Male
SA261074	90421016810	Training	1 week of training or control time	Male
SA261075	90426016810	Training	1 week of training or control time	Male
SA261076	90578016810	Training	2 weeks of training	Female
SA261077	90576016810	Training	2 weeks of training	Female
SA261078	90581016810	Training	2 weeks of training	Female
SA261079	90585016810	Training	2 weeks of training	Female
SA261080	90587016810	Training	2 weeks of training	Female
SA261081	90450016810	Training	2 weeks of training	Male
SA261082	90441016810	Training	2 weeks of training	Male
SA261083	90444016810	Training	2 weeks of training	Male
SA261084	90449016810	Training	2 weeks of training	Male
SA261085	90439016810	Training	2 weeks of training	Male
SA261086	90412016810	Training	4 weeks of training	Female
SA261087	90406016810	Training	4 weeks of training	Female
SA261088	90410016810	Training	4 weeks of training	Female
SA261089	90416016810	Training	4 weeks of training	Female
SA261090	90420016810	Training	4 weeks of training	Female
SA261091	90280016810	Training	4 weeks of training	Male
SA261092	90289016810	Training	4 weeks of training	Male
SA261093	90283016810	Training	4 weeks of training	Male
SA261094	90292016810	Training	4 weeks of training	Male
SA261095	90281016810	Training	4 weeks of training	Male
SA261096	90254016810	Training	8 weeks of training or control time	Female
SA261097	90251016810	Training	8 weeks of training or control time	Female
SA261098	90259016810	Training	8 weeks of training or control time	Female
SA261099	90258016810	Training	8 weeks of training or control time	Female
SA261100	90267016810	Training	8 weeks of training or control time	Female
SA261101	90222016810	Training	8 weeks of training or control time	Male
SA261102	90227016810	Training	8 weeks of training or control time	Male
SA261103	90218016810	Training	8 weeks of training or control time	Male
SA261104	90225016810	Training	8 weeks of training or control time	Male
SA261105	90223016810	Training	8 weeks of training or control time	Male

Showing results 1 to 79 of 79

Showing results 1 to 79 of 79