Summary of Study ST001248
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000835. The data can be accessed directly via it's Project DOI: 10.21228/M8RH65 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST001248 |
| Study Title | The cecal and fecal metabolomes of horses before and after metronidazole administration |
| Study Summary | Metronidazole (15mg/kg BID PO) was given to horses (n=5) with in-dwelling cecal cannulas. The study was suspended after the fifth dose (day 3) due to adverse gastrointestinal effects. Cecal and fecal samples were obtained before and after (Days days -52, -28, -14, 0, 7, 14, 28 and 52) metronidazole administration. The metabolome was characterized by mass spectrometry-based methods. Fecal, but not cecal metabolites were affected by metronidazole. The fecal metabolites affected represented diverse metabolic pathways such as nucleic acid metabolism, secondary bile metabolism, fatty acid synthesis/degradation/elongation or metabolism and sugar metabolism. |
| Institute | Texas A&M University |
| Department | Department of Small Animal Clinical Sciences |
| Laboratory | Gastrointestinal Laboratory |
| Last Name | Arnold |
| First Name | Carolyn |
| Address | 4474 TAMU |
| carnold@cvm.tamu.edu | |
| Phone | 979 845 3541 |
| Submit Date | 2019-09-04 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | cdf |
| Analysis Type Detail | MALDI-MS |
| Release Date | 2020-03-03 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Factors:
Subject type: Mammal; Subject species: Equus caballus (Factor headings shown in green)
| mb_sample_id | local_sample_id | organ | Day | Treatment |
|---|---|---|---|---|
| SA090893 | AlvinD0_058 | cecal | D0 | No |
| SA090894 | FrankD0_037 | cecal | D0 | No |
| SA090895 | SteveD0_042 | cecal | D0 | No |
| SA090896 | ErnieD0_053 | cecal | D0 | Yes |
| SA090897 | BillyD0_047 | cecal | D0 | Yes |
| SA090884 | AlvinD-14_057 | cecal | D-14 | No |
| SA090885 | FrankD-14_036 | cecal | D-14 | No |
| SA090886 | ErnieD-14_052 | cecal | D-14 | No |
| SA090887 | SteveD-14_041 | cecal | D-14 | No |
| SA090888 | BillyD-14_046 | cecal | D-14 | No |
| SA090898 | BillyD14_049 | cecal | D14 | Yes |
| SA090899 | AlvinD14_060 | cecal | D14 | Yes |
| SA090900 | FrankD14_039 | cecal | D14 | Yes |
| SA090901 | SteveD14_043 | cecal | D14 | Yes |
| SA090902 | ErnieD14_055 | cecal | D14 | Yes |
| SA090889 | ErnieD-28_051 | cecal | D-28 | No |
| SA090890 | BillyD-28_045 | cecal | D-28 | No |
| SA090891 | AlvinD-28_056 | cecal | D-28 | No |
| SA090892 | FrankD-28_035 | cecal | D-28 | No |
| SA090903 | SteveD28_044 | cecal | D28 | No |
| SA090904 | FrankD28_040 | cecal | D28 | Yes |
| SA090905 | BillyD28_050 | cecal | D28 | Yes |
| SA090906 | AlvinD28_061 | cecal | D28 | Yes |
| SA090907 | SteveD7_062 | cecal | D7 | Yes |
| SA090908 | BillyD7_048 | cecal | D7 | Yes |
| SA090909 | ErnieD7_054 | cecal | D7 | Yes |
| SA090910 | FrankD7_038 | cecal | D7 | Yes |
| SA090911 | AlvinD7_059 | cecal | D7 | Yes |
| SA090920 | AlvinD0_033 | fecal | D0 | No |
| SA090921 | AlvinD0_032 | fecal | D0 | No |
| SA090922 | SteveD0_010 | fecal | D0 | No |
| SA090923 | ErnieD0_024 | fecal | D0 | No |
| SA090924 | AlvinD0_031 | fecal | D0 | No |
| SA090925 | FrankD0_003 | fecal | D0 | No |
| SA090926 | BillyD0_017 | fecal | D0 | No |
| SA090927 | AlvinD0_030 | fecal | D0 | No |
| SA090912 | BillyD-14_016 | fecal | D-14 | No |
| SA090913 | SteveD-14_009 | fecal | D-14 | No |
| SA090914 | ErnieD-14_023 | fecal | D-14 | No |
| SA090915 | FrankD-14_002 | fecal | D-14 | No |
| SA090928 | SteveD14_013 | fecal | D14 | Yes |
| SA090929 | BillyD14_020 | fecal | D14 | Yes |
| SA090930 | ErnieD14_027 | fecal | D14 | Yes |
| SA090931 | FrankD14_006 | fecal | D14 | Yes |
| SA090916 | ErnieD-28_022 | fecal | D-28 | No |
| SA090917 | FrankD-28_001 | fecal | D-28 | No |
| SA090918 | SteveD-28_008 | fecal | D-28 | No |
| SA090919 | BillyD-28_015 | fecal | D-28 | No |
| SA090932 | SteveD28_014 | fecal | D28 | Yes |
| SA090933 | FrankD28_007 | fecal | D28 | Yes |
| SA090934 | AlvinD28_034 | fecal | D28 | Yes |
| SA090935 | BillyD28_021 | fecal | D28 | Yes |
| SA090936 | AlvinD3_031 | fecal | D3 | Yes |
| SA090937 | BillyD3_018 | fecal | D3 | Yes |
| SA090938 | ErnieD3_025 | fecal | D3 | Yes |
| SA090939 | SteveD3_011 | fecal | D3 | Yes |
| SA090940 | FrankD3_004 | fecal | D3 | Yes |
| SA090941 | BillyD7_019 | fecal | D7 | Yes |
| SA090942 | FrankD7_005 | fecal | D7 | Yes |
| SA090943 | AlvinD7_032 | fecal | D7 | Yes |
| SA090944 | SteveD7_012 | fecal | D7 | Yes |
| SA090945 | ErnieD7_026 | fecal | D7 | Yes |
| Showing results 1 to 62 of 62 |
