Summary of Study ST001790

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001137. The data can be accessed directly via it's Project DOI: 10.21228/M8R102 This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST001790
Study TitleEffect of external low-dose rate radiation on mouse biofluid metabolomic signatures (part I)
Study SummaryAn important component of ionizing radiation (IR) exposure after a radiological incident may include low-dose rate (LDR) exposures either externally or internally, such as from 137Cs deposition. LDR exposures can have different effects compared to acute high-dose rate exposures from a health and biodosimetry perspective. In this study, a novel irradiation system, VAriable Dose-rate External 137Cs irradiatoR (VADER), was used to expose male and female mice to a variable LDR over a 30-day time span to cumulative doses of 1 (only in males), 2, 2.8, 4.1, 8.8 (only in males), or 9.7 Gy to simulate fall-out type exposures. Urine and serum from mice exposed to an acute dose (~0.8 Gy/min) of x-rays were collected in parallel. Radiation markers were identified by global mass spectrometry based metabolomics and the machine learning algorithm Random Forests.
Institute
Georgetown University
Last NamePannkuk
First NameEvan
Address3970 Reservoir Rd, NW New Research Building E504
Emailelp44@georgetown.edu
Phone2026875650
Submit Date2021-05-11
Raw Data AvailableYes
Raw Data File Type(s)raw(Waters)
Analysis Type DetailLC-MS
Release Date2021-12-15
Release Version1
Evan Pannkuk Evan Pannkuk
https://dx.doi.org/10.21228/M8R102
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Factors:

Subject type: Mammal; Subject species: Mus musculus (Factor headings shown in green)

mb_sample_id local_sample_id Factor
SA16656556Control | Factor:post
SA166566194Control | Factor:post
SA166567112Control | Factor:post
SA166568138Control | Factor:post
SA16656962Control | Factor:post
SA166570134Control | Factor:post
SA16657194Control | Factor:post
SA166572204Control | Factor:post
SA166573205Control | Factor:post
SA16657450Control | Factor:post
SA16657551Control | Factor:post
SA16657664Control | Factor:post
SA16657793Control | Factor:post
SA16657866Control | Factor:post
SA166579167Control | Factor:post
SA166580179Control | Factor:post
SA166581146Control | Factor:post
SA166582147Control | Factor:post
SA166583154Control | Factor:post
SA16658475Control | Factor:post
SA166585180Control | Factor:post
SA16658667Control | Factor:post
SA16658786Control | Factor:post
SA166588185Control | Factor:post
SA166589184Control | Factor:post
SA166590182Control | Factor:post
SA16659165Control | Factor:post
SA16659244Control | Factor:post
SA16659343Control | Factor:post
SA166594236Control | Factor:post
SA166595229Control | Factor:post
SA166596232Control | Factor:post
SA166597234Control | Factor:post
SA166598255Control | Factor:post
SA166599119Control | Factor:post
SA166600102Control | Factor:post
SA16660113Control | Factor:post
SA166602113Control | Factor:post
SA16660340Control | Factor:post
SA16660441Control | Factor:post
SA16660542Control | Factor:post
SA166606207Control | Factor:post
SA16660738Control | Factor:post
SA16660810Control | Factor:post
SA166609107Control | Factor:post
SA166610210Control | Factor:post
SA16661135Control | Factor:post
SA166612141Control | Factor:pre
SA166613127Control | Factor:pre
SA166614132Control | Factor:pre
SA1666159Control | Factor:pre
SA166616131Control | Factor:pre
SA166617139Control | Factor:pre
SA166618117Control | Factor:pre
SA166619121Control | Factor:pre
SA166620115Control | Factor:pre
SA166621191Control | Factor:pre
SA166622247Control | Factor:pre
SA166623238Control | Factor:pre
SA166624230Control | Factor:pre
SA166625225Control | Factor:pre
SA166626250Control | Factor:pre
SA166627251Control | Factor:pre
SA166628220Control | Factor:pre
SA166629254Control | Factor:pre
SA166630253Control | Factor:pre
SA166631223Control | Factor:pre
SA166632218Control | Factor:pre
SA166633168Control | Factor:pre
SA166634165Control | Factor:pre
SA166635155Control | Factor:pre
SA166636186Control | Factor:pre
SA166637190Control | Factor:pre
SA166638197Control | Factor:pre
SA166639196Control | Factor:pre
SA166640195Control | Factor:pre
SA166641152Control | Factor:pre
SA166642133Control | Factor:pre
SA16664382Control | Factor:pre
SA166644108Control | Factor:pre
SA16664589Control | Factor:pre
SA16664624Control | Factor:pre
SA16664799Control | Factor:pre
SA16664895Control | Factor:pre
SA16664968Control | Factor:pre
SA16665063Control | Factor:pre
SA16665139Control | Factor:pre
SA16665248Control | Factor:pre
SA16665337Control | Factor:pre
SA16665457Control | Factor:pre
SA16665561Control | Factor:pre
SA16665623Control | Factor:pre
SA16665727Control | Factor:pre
SA16665815Control | Factor:pre
SA16665912Control | Factor:pre
SA166660203HDR | Factor:post
SA166661171HDR | Factor:post
SA166662151HDR | Factor:post
SA166663153HDR | Factor:post
SA166664216HDR | Factor:post
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