Summary of Study ST001791
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001137. The data can be accessed directly via it's Project DOI: 10.21228/M8R102 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST001791 |
| Study Title | Effect of external low-dose rate radiation on mouse biofluid metabolomic signatures (part II) |
| Study Summary | An important component of ionizing radiation (IR) exposure after a radiological incident may include low-dose rate (LDR) exposures either externally or internally, such as from 137Cs deposition. LDR exposures can have different effects compared to acute high-dose rate exposures from a health and biodosimetry perspective. In this study, a novel irradiation system, VAriable Dose-rate External 137Cs irradiatoR (VADER), was used to expose male and female mice to a variable LDR over a 30-day time span to cumulative doses of 1 (only in males), 2, 2.8, 4.1, 8.8 (only in males), or 9.7 Gy to simulate fall-out type exposures. Urine and serum from mice exposed to an acute dose (~0.8 Gy/min) of x-rays were collected in parallel. Radiation markers were identified by global mass spectrometry based metabolomics and the machine learning algorithm Random Forests. |
| Institute | Georgetown University |
| Last Name | Pannkuk |
| First Name | Evan |
| Address | 3970 Reservoir Rd, NW New Research Building E504 |
| elp44@georgetown.edu | |
| Phone | 2026875650 |
| Submit Date | 2021-05-11 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | raw(Waters) |
| Analysis Type Detail | LC-MS |
| Release Date | 2021-12-15 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Factors:
Subject type: Mammal; Subject species: Mus musculus (Factor headings shown in green)
| mb_sample_id | local_sample_id | Factor | Factor |
|---|---|---|---|
| SA166757 | 115 | A | post |
| SA166758 | 63 | Control | post |
| SA166759 | 61 | Control | post |
| SA166760 | 159 | Control | post |
| SA166761 | 66 | Control | post |
| SA166762 | 107 | Control | post |
| SA166763 | 52 | Control | post |
| SA166764 | 116 | Control | post |
| SA166765 | 165 | Control | post |
| SA166766 | 48 | Control | post |
| SA166767 | 101 | Control | post |
| SA166768 | 112 | Control | post |
| SA166769 | 70 | Control | post |
| SA166770 | 151 | Control | post |
| SA166771 | 216 | Control | post |
| SA166772 | 150 | Control | post |
| SA166773 | 88 | Control | post |
| SA166774 | 144 | Control | post |
| SA166775 | 80 | Control | post |
| SA166776 | 143 | Control | post |
| SA166777 | 138 | Control | post |
| SA166778 | 74 | Control | post |
| SA166779 | 222 | Control | post |
| SA166780 | 193 | Control | post |
| SA166781 | 192 | Control | post |
| SA166782 | 231 | Control | post |
| SA166783 | 25 | Control | post |
| SA166784 | 24 | Control | post |
| SA166785 | 185 | Control | post |
| SA166786 | 40 | Control | post |
| SA166787 | 28 | Control | post |
| SA166788 | 22 | Control | post |
| SA166789 | 17 | Control | post |
| SA166790 | 241 | Control | post |
| SA166791 | 10 | Control | post |
| SA166792 | 184 | Control | post |
| SA166793 | 177 | Control | post |
| SA166794 | 238 | Control | post |
| SA166795 | 170 | Control | post |
| SA166796 | 27 | Control | post |
| SA166797 | 120 | Control | post |
| SA166798 | 125 | Control | post |
| SA166799 | 207 | Control | post |
| SA166800 | 38 | Control | post |
| SA166801 | 209 | Control | post |
| SA166802 | 130 | Control | pre |
| SA166803 | 95 | Control | pre |
| SA166804 | 139 | Control | pre |
| SA166805 | 94 | Control | pre |
| SA166806 | 182 | Control | pre |
| SA166807 | 113 | Control | pre |
| SA166808 | 91 | Control | pre |
| SA166809 | 202 | Control | pre |
| SA166810 | 141 | Control | pre |
| SA166811 | 103 | Control | pre |
| SA166812 | 105 | Control | pre |
| SA166813 | 126 | Control | pre |
| SA166814 | 196 | Control | pre |
| SA166815 | 140 | Control | pre |
| SA166816 | 104 | Control | pre |
| SA166817 | 9 | Control | pre |
| SA166818 | 137 | Control | pre |
| SA166819 | 100 | Control | pre |
| SA166820 | 68 | Control | pre |
| SA166821 | 39 | Control | pre |
| SA166822 | 234 | Control | pre |
| SA166823 | 44 | Control | pre |
| SA166824 | 164 | Control | pre |
| SA166825 | 145 | Control | pre |
| SA166826 | 36 | Control | pre |
| SA166827 | 168 | Control | pre |
| SA166828 | 16 | Control | pre |
| SA166829 | 172 | Control | pre |
| SA166830 | 237 | Control | pre |
| SA166831 | 169 | Control | pre |
| SA166832 | 54 | Control | pre |
| SA166833 | 229 | Control | pre |
| SA166834 | 78 | Control | pre |
| SA166835 | 65 | Control | pre |
| SA166836 | 55 | Control | pre |
| SA166837 | 198 | Control | pre |
| SA166838 | 219 | Control | pre |
| SA166839 | 62 | Control | pre |
| SA166840 | 228 | Control | pre |
| SA166841 | 146 | Control | pre |
| SA166842 | 57 | Control | pre |
| SA166843 | 86 | Control | pre |
| SA166844 | 176 | HDR | post |
| SA166845 | 132 | HDR | post |
| SA166846 | 157 | HDR | post |
| SA166847 | 190 | HDR | post |
| SA166848 | 166 | HDR | post |
| SA166849 | 189 | HDR | post |
| SA166850 | 153 | HDR | post |
| SA166851 | 93 | HDR | post |
| SA166852 | 41 | HDR | post |
| SA166853 | 215 | HDR | post |
| SA166854 | 89 | HDR | post |
| SA166855 | 232 | HDR | post |
| SA166856 | 223 | HDR | post |
