Summary of Study ST001987

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001263. The data can be accessed directly via it's Project DOI: 10.21228/M8FX3C This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST001987
Study TitleTranscriptomic and lipidomic analysis unravels the response of Faecalibacterium prausnitzii to calcium palmitate
Study SummaryInfant formula is a suggested alternative to human milk if breastfeeding is not an option; vegetable oil blends are commonly used in infant formula (IF) to replace dairy fat, which can induce the formation of the poorly soluble soap calcium palmitate (CP) in the infant’s gut. Previously, we observed that CP at a low concentration of 0.01 mg/ml inhibits the growth of dominant infant bacteria such as Faecalibacterium prausnitzii both during the exponential phase as well as in the stationary phase. Here, we investigate the underlying mechanism of the CP inhibition on infant-gut bacteria using F. prausnitzii as a model by analysing its growth at a transcriptomic and lipidomic level.
Institute
University of Groningen
Last NameHorvatovich
First NamePéter
AddressAntonius Deusinglaan 1, 9713 AV Groningen, The Netherlands
Emailp.l.horvatovich@rug.nl
Phone+31 (0)50 363 3341
Submit Date2021-11-12
Raw Data AvailableYes
Raw Data File Type(s)mzML
Analysis Type DetailLC-MS
Release Date2021-12-15
Release Version1
Péter Horvatovich Péter Horvatovich
https://dx.doi.org/10.21228/M8FX3C
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

Select appropriate tab below to view additional metadata details:

Factors:

Subject type: Bacteria; Subject species: Faecalibacterium prausnitzii (Factor headings shown in green)

mb_sample_id local_sample_id Factor
SA185849Neg38CP0Hour16 Negative
SA185850Neg41CP0Hour16 Negative
SA185851Neg8CP0Hour16 Negative
SA185852Neg35CP0Hour16 Negative
SA185853Neg42CP0Hour16 Negative
SA185854Neg26CP0Hour16 Negative
SA185855Neg18CP0Hour16 Negative
SA185856Neg19CP0Hour16 Negative
SA185857Neg20CP0Hour16 Negative
SA185858Neg7CP0Hour16 Negative
SA185859Neg30CP0Hour16 Negative
SA185860Neg13CP0Hour16 Negative
SA185861Pos26CP0Hour16 Positive
SA185862Pos20CP0Hour16 Positive
SA185863Pos19CP0Hour16 Positive
SA185864Pos18CP0Hour16 Positive
SA185865Pos35CP0Hour16 Positive
SA185866Pos38CP0Hour16 Positive
SA185867Pos7CP0Hour16 Positive
SA185868Pos8CP0Hour16 Positive
SA185869Pos42CP0Hour16 Positive
SA185870Pos41CP0Hour16 Positive
SA185871Pos13CP0Hour16 Positive
SA185872Pos30CP0Hour16 Positive
SA185873Neg23CP0Hour5 Negative
SA185874Neg29CP0Hour5 Negative
SA185875Neg22CP0Hour5 Negative
SA185876Neg21CP0Hour5 Negative
SA185877Neg6CP0Hour5 Negative
SA185878Neg33CP0Hour5 Negative
SA185879Neg17CP0Hour5 Negative
SA185880Neg16CP0Hour5 Negative
SA185881Neg43CP0Hour5 Negative
SA185882Neg5CP0Hour5 Negative
SA185883Neg36CP0Hour5 Negative
SA185884Neg37CP0Hour5 Negative
SA185885Pos36CP0Hour5 Positive
SA185886Pos37CP0Hour5 Positive
SA185887Pos43CP0Hour5 Positive
SA185888Pos33CP0Hour5 Positive
SA185889Pos6CP0Hour5 Positive
SA185890Pos21CP0Hour5 Positive
SA185891Pos16CP0Hour5 Positive
SA185892Pos17CP0Hour5 Positive
SA185893Pos22CP0Hour5 Positive
SA185894Pos23CP0Hour5 Positive
SA185895Pos29CP0Hour5 Positive
SA185896Pos5CP0Hour5 Positive
SA185897Neg4CP2Hour16 Negative
SA185898Neg39CP2Hour16 Negative
SA185899Neg45CP2Hour16 Negative
SA185900Neg47CP2Hour16 Negative
SA185901Neg10CP2Hour16 Negative
SA185902Neg32CP2Hour16 Negative
SA185903Neg48CP2Hour16 Negative
SA185904Neg31CP2Hour16 Negative
SA185905Neg15CP2Hour16 Negative
SA185906Neg12CP2Hour16 Negative
SA185907Neg25CP2Hour16 Negative
SA185908Neg27CP2Hour16 Negative
SA185909Pos27CP2Hour16 Positive
SA185910Pos25CP2Hour16 Positive
SA185911Pos15CP2Hour16 Positive
SA185912Pos31CP2Hour16 Positive
SA185913Pos12CP2Hour16 Positive
SA185914Pos39CP2Hour16 Positive
SA185915Pos48CP2Hour16 Positive
SA185916Pos10CP2Hour16 Positive
SA185917Pos45CP2Hour16 Positive
SA185918Pos4CP2Hour16 Positive
SA185919Pos32CP2Hour16 Positive
SA185920Pos47CP2Hour16 Positive
SA185921Neg28CP2Hour5 Negative
SA185922Neg2CP2Hour5 Negative
SA185923Neg14CP2Hour5 Negative
SA185924Neg11CP2Hour5 Negative
SA185925Neg1CP2Hour5 Negative
SA185926Neg24CP2Hour5 Negative
SA185927Neg3CP2Hour5 Negative
SA185928Neg46CP2Hour5 Negative
SA185929Neg44CP2Hour5 Negative
SA185930Neg40CP2Hour5 Negative
SA185931Neg34CP2Hour5 Negative
SA185932Neg9CP2Hour5 Negative
SA185933Pos9CP2Hour5 Positive
SA185934Pos34CP2Hour5 Positive
SA185935Pos40CP2Hour5 Positive
SA185936Pos44CP2Hour5 Positive
SA185937Pos46CP2Hour5 Positive
SA185938Pos3CP2Hour5 Positive
SA185939Pos28CP2Hour5 Positive
SA185940Pos11CP2Hour5 Positive
SA185941Pos14CP2Hour5 Positive
SA185942Pos2CP2Hour5 Positive
SA185943Pos24CP2Hour5 Positive
SA185944Pos1CP2Hour5 Positive
Showing results 1 to 96 of 96
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