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MB Sample ID: SA183522
| Local Sample ID: | D13 |
| Subject ID: | SU002024 |
| Subject Type: | Human |
| Subject Species: | Homo sapiens |
| Taxonomy ID: | 9606 |
| Age Or Age Range: | 19-79 |
| Weight Or Weight Range: | 49-93 |
| Height Or Height Range: | 1.5-1.9 |
| Gender: | Male and female |
| Human Ethnicity: | Brazilian |
| Human Medications: | BD patients used a wide range of different medications, mostly mood stabilizers and antipsychotics |
| Human Inclusion Criteria: | Controls: Any adult over 18 years respecting the excusion criteria / BD: Any adult over 18 years old with BD diagnosed by a psychiatrist, respecting exclusion criteria psychiat |
| Human Exclusion Criteria: | Controls : negative history of any psychiatric disorder or use of any kind of psychiatric medication / BD : concomitant diseases such as AIDS, hepatitis, endocrinal or metabolic diseases, substance use (except nicotine dependence), and pregnancy or postpartum period |
Select appropriate tab below to view additional metadata details:
Combined analysis:
| Analysis ID | AN003168 |
|---|---|
| Analysis type | MS |
| Chromatography type | GC |
| Chromatography system | HP/Agilent 5890 Series II |
| Column | HP5-MS (30m x 0.25mm x 0.25um) + Duragard precolumn (10m) |
| MS Type | EI |
| MS instrument type | Single quadrupole |
| MS instrument name | HP 5970 Series Quadrupole Mass Selective Detector |
| Ion Mode | UNSPECIFIED |
| Units | Intensities after normalization by Internal standard and log2 transformed |
MS:
| MS ID: | MS002946 |
| Analysis ID: | AN003168 |
| Instrument Name: | HP 5970 Series Quadrupole Mass Selective Detector |
| Instrument Type: | Single quadrupole |
| MS Type: | EI |
| MS Comments: | The GC-MS conditions were the same as required to use the FiehnLib library (Kind et al., 2009). The data obtained were exported as ‘.AIA’ format in GC Chemstation then transformed in ‘.d’ using Agilent GC-MS translator and finally converted in ‘.abf’ format using MS-DIAL ABF file converter. The ‘.abf’ files were then analyzed in MS-DIAL (version 4.16) for peak picking, deconvolution and peak identification. The peak table containing the identifications from FiehnLib and the respective intensities in total ion chromatogram (TIC) from each metabolite were exported and analyzed using R statistical programming language (version 3.60) to evaluate the relative standard deviations (RSD) from each metabolite on the QC samples. Metabolites with RSD > 30 % were discarded due to excessive deviation through the batch. We opted to perform a second curation of the identifications using Golm Metabolite Database (GMD) since was observed a deviation of ± 0.2 minutes on the identifications comparing to the value shown in the library, caused possibly by the equipment. Metabolites that presented inconsistencies between both platforms were considered unknown, where some of these were just identified by their functional groups using one of GMD functionalities. |
| Ion Mode: | UNSPECIFIED |
