Summary of Study ST002417
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001556. The data can be accessed directly via it's Project DOI: 10.21228/M8K429 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
Study ID | ST002417 |
Study Title | Serum metabolomics and lipidomics profiling in iliac arteriovenous fistula creation in clinical patients: part 1 |
Study Type | Study of the serum metabolome in patients with end stage kidney disease before and 6-weeks after iliac arteriovenous fistula creation via 1H NMR |
Study Summary | This project is focused on a longitudinal analysis of the small molecules metabolomes in end stage renal disease patients undergoing iliac arteriovenous fistula creation using solution state NMR spectroscopy. It was hypothesized that after 6-weeks of AVF creation, these patients would present with altered serum metabolite features. |
Institute | University of Florida |
Department | Applied Physiology and Kinesiology |
Laboratory | Rm 42 and Rm 43 |
Last Name | Khattri |
First Name | Ram |
Address | 1864 Stadium RD, Gainesville, FL, 32611, USA |
rbk11@ufl.edu | |
Phone | 3307856045 |
Submit Date | 2022-12-22 |
Num Groups | 2 |
Total Subjects | 45 subjects, 2 samples per subject, total of 90 samples |
Num Males | 36 |
Num Females | 9 |
Study Comments | Study of the serum metabolome in patients with end stage kidney disease before and 6-weeks after iliac arteriovenous fistula creation via 1H NMR |
Raw Data Available | Yes |
Raw Data File Type(s) | fid |
Analysis Type Detail | NMR |
Release Date | 2023-12-22 |
Release Version | 1 |
Select appropriate tab below to view additional metadata details:
NMR:
NMR ID: | NM000259 |
Analysis ID: | AN003938 |
Instrument Name: | Bruker 600 MHz |
Instrument Type: | FT-NMR |
NMR Experiment Type: | 1D-1H |
Field Frequency Lock: | Deuterium |
Standard Concentration: | 0.5mM DSS |
Spectrometer Frequency: | 600 MHz |
NMR Probe: | 5mm TXI CryoProbe |
NMR Solvent: | Phosphate buffer (pH 7.2) + 2 mM EDTA + 0.5 mM DSS + 0.2% of sodium azide in deuterated environment |
NMR Tube Size: | 5 mm O.D. |
Shimming Method: | Topshim |
Pulse Sequence: | noesypr1d |
Water Suppression: | presat |
Pulse Width: | 90-degree |
Receiver Gain: | 202.2 |
Offset Frequency: | 4.77 ppm |
Chemical Shift Ref Cpd: | DSS |
Temperature: | 298.2 oK |
Number Of Scans: | 128 |
Dummy Scans: | 8 |
Acquisition Time: | 4s |
Relaxation Delay: | 1s |
Spectral Width: | 9578.5 |
Num Data Points Acquired: | 38313 |
Real Data Points: | 65536 |
Line Broadening: | 0.22 Hz |
Zero Filling: | 65,536 points |
Apodization: | Exponential |
Baseline Correction Method: | Spline |
Chemical Shift Ref Std: | 0 ppm for DSS |
Binned Increment: | NA |
Binned Data Protocol File: | NA |
Binned Data Excluded Range: | NA |