Summary of Study ST002156
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001369. The data can be accessed directly via it's Project DOI: 10.21228/M8RQ67 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
Study ID | ST002156 |
Study Title | Mouse liver metabolites |
Study Summary | Western diet (WD) and gut microbiota interplay drives the development of non-alcoholic fatty liver disease (NAFLD) and its progression to non-alcoholic steatohepatitis (NASH). However, the metabolic mediators contributing to NASH remain to be identified. In this study, we explored the change of liver metabolites in a diet-induced mouse NASH model. Identification of these metabolites will help to uncover the pathogenesis of NASH and explore the new therapeutic treatment. |
Institute | University of Missouri-Columbia |
Last Name | Yang |
First Name | Ming |
Address | University of Missouri |
yangmin@health.missouri.edu | |
Phone | 5738827141 |
Submit Date | 2022-04-24 |
Analysis Type Detail | GC-MS |
Release Date | 2022-05-16 |
Release Version | 1 |
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Sample Preparation:
Sampleprep ID: | SP002248 |
Sampleprep Summary: | Briefly, liver tissues (50-100 mg) are typically homogenized in the extraction solvent using a bead beater. These samples are then centrifuged at 13,000 g for 15 min to pellet tissue and proteins. The supernatant is combined with water and chloroform, including internal standards, to separate into the polar and non-polar phases. |
Processing Storage Conditions: | -80℃ |
Extract Storage: | -80℃ |