Summary of Study ST000946
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000651. The data can be accessed directly via it's Project DOI: 10.21228/M8HX17 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
Study ID | ST000946 |
Study Title | Untargeted Metabolomics of T1 Participants |
Study Type | MS analysis |
Study Summary | Specific Aims: (a) Identify sex differences in serum untargeted metabolomics profiles during late adolescence, (b) examine changes in metabolomics profiles between early and late adolescence in the same children, and (c) evaluate associations of exposure to prenatal and concurrent exposure to PAHs, metals, and EDCs with serum metabolite profiles among boys and girls, separately, during late adolescence. |
Institute | University of Michigan |
Department | Biomedical Research Core Facilities |
Laboratory | Metabolomics core |
Last Name | Kachman |
First Name | Maureen |
Address | 6300 Brehm Tower, 1000 Wall Street, Ann Arbor, MI 48105-5714 |
mkachman@med.umich.edu | |
Phone | (734) 232-8175 |
Submit Date | 2018-03-14 |
Num Groups | 2 |
Total Subjects | 207 |
Study Comments | The overall objective of this project is to expand upon available data from Early Life Exposure in Mexico to ENvironental Toxicants (ELEMENT) Project to examine effects of toxicant exposures during three sensitive developmental timeframes – the prenatal period, early adolescence, and late adolescence – on adiposity and metabolic risk in adolescence with an emphasis on sex differences and the related molecular underpinnings. In addition to existing exposure data on BPA, metals and phthalates, we propose to add measures of polycyclic aromatic hydrocarbon (PAH) metabolites in archived urine samples from mothers and children. We also propose to assess the epigenome at three developmental periods (prenatal aka in utero, early and late adolescence) and the circulating metabolome during late adolescence. We will incorporate data on toxicant exposures and ‘omics, including untargeted metabolomics of 404 teenagers from the ELEMENT cohorts, to addressing several specific aims. |
Raw Data Available | Yes |
Raw Data File Type(s) | d |
Chear Study | Yes |
Analysis Type Detail | LC-MS |
Release Date | 2021-08-31 |
Release Version | 1 |
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Subject:
Subject ID: | SU000985 |
Subject Type: | Human |
Subject Species: | Homo sapiens |
Taxonomy ID: | 9606 |