Metabolomics Workbench : NIH Data Repository

MB Sample ID: SA205291

Local Sample ID:	T11_3
Subject ID:	SU002222
Subject Type:	Mammal
Subject Species:	Mus musculus
Taxonomy ID:	10090

Select appropriate tab below to view additional metadata details:

Treatment:

Treatment ID:	TR002234
Treatment Summary:	TKO p53LSL R172H/+ Dicer1flox/flox Ptenflox/flox Amhr2cre/+ mice were generated by mating p53LSL-R172H/+Dicer1flox/floxPtenflox/flox female mice with Dicer1flox/floxPtenflox/floxAmhr2cre/+ male mice. For TKO controls, p53LSL-R172H/+Dicer1flox/floxPtenflox/flox were generated. TKO control mice carry the same genetic makeup as TKO mice but do not develop HGSC. A sequential serum collection protocol was conducted to collect samples from TKO and TKO controls every two weeks starting at 8 weeks of age until a humane end point for sacrifice or development of ascites. TKO mice were sacrificed at Indiana University School of Medicine in accordance with animal protocol (21124) approved by the IACUC.

Treatment ID:

TR002234

Treatment Summary:

TKO p53LSL R172H/+ Dicer1flox/flox Ptenflox/flox Amhr2cre/+ mice were generated by mating p53LSL-R172H/+Dicer1flox/floxPtenflox/flox female mice with Dicer1flox/floxPtenflox/floxAmhr2cre/+ male mice. For TKO controls, p53LSL-R172H/+Dicer1flox/floxPtenflox/flox were generated. TKO control mice carry the same genetic makeup as TKO mice but do not develop HGSC. A sequential serum collection protocol was conducted to collect samples from TKO and TKO controls every two weeks starting at 8 weeks of age until a humane end point for sacrifice or development of ascites. TKO mice were sacrificed at Indiana University School of Medicine in accordance with animal protocol (21124) approved by the IACUC.