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MB Sample ID: SA210157
Local Sample ID: | Terence_MS3_Quad_Aq |
Subject ID: | SU002275 |
Subject Type: | Mammal |
Subject Species: | Mus musculus |
Genotype Strain: | C57BL/6J |
Age Or Age Range: | 13 weeks |
Weight Or Weight Range: | (28.4±1.1 g (control SHAM mice) vs 26.4±2.1 g (control AVF mice) vs 23.6±2.1 (CKD SHAM mice) vs 24.7±1.3 (CKD AVF mice), N=8-10/group). |
Gender: | Male |
Animal Animal Supplier: | Jackson Labs (Stock # 000664) |
Animal Housing: | Housed in a temperature of 22 oC |
Animal Light Cycle: | 12-hour light/12-hour dark |
Animal Feed: | Ad libitum (Casein control diet vs. adenine-supplemented diet to induce CKD) |
Animal Water: | free access to food and water (3-5 animals per cage). |
Animal Inclusion Criteria: | (3-5 animals per cage). |
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Treatment:
Treatment ID: | TR002287 |
Treatment Summary: | Briefly, mice were acclimated to a standard casein-based chow (Control Diet) for 7 days. Thereafter, the animals were randomly assign to either remain on Control Diet (non-CKD groups) or receive adenine-supplemented diet to induce CKD. Following three weeks of the casein/adenine diet, animals were randomly assigned to receive either an arteriovenous fistula surgery (AVF) or sham surgery (SHAM) |
Animal Vet Treatments: | none |
Animal Anesthesia: | isoflurane |
Animal Fasting: | non-fasted |
Animal Endp Euthanasia: | Euthanasia was carried out by thoracotomy followed by cervical dislocation. |
Animal Endp Tissue Coll List: | Skeletal muscle (quadriceps) |