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MB Sample ID: SA254743
| Local Sample ID: | T-A6 |
| Subject ID: | SU002632 |
| Subject Type: | Mammal |
| Subject Species: | Mus musculus |
| Taxonomy ID: | 10090 |
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Treatment:
| Treatment ID: | TR002644 |
| Treatment Summary: | 8 weeks old C57BL/6 male mice were randomly divided into three groups: control group (control; n=8), cisplatin-induced AKI group (cisplatin; n=8), and cisplatin plus TRAF1 plasmid injection group (cisplatin + TRAF1; n=8). Both cisplatin and cisplatin + TRAF1 groups were given 20 mg/kg cisplatin intraperitoneal (i.p.) injection, while the control group received the same amount of saline i.p. injection. The mice in cisplatin + TRAF1 group were pretreated with TRAF1 performed by a hydrodynamic-based gene delivery approach 36 h before cisplatin administration. Mice in the three groups were sacrificed after cisplatin treatment for 72 h. The kidney tissues were cut horizontally and collected. |
| Treatment Protocol Filename: | protocol.pdf |
