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MB Sample ID: SA308642
Local Sample ID: | tumor-enzalutamide-3-01 |
Subject ID: | SU002964 |
Subject Type: | Mammal |
Subject Species: | Mus musculus |
Genotype Strain: | NSG |
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Treatment:
Treatment ID: | TR002973 |
Treatment Summary: | 7 million 16D cells were implanted subcutaneously with 100 μl Matrigel (Corning) into NSG mice to form primary tumors. Primary tumors were harvested, minced, and re-implanted (20 - 80 mg of minced tumor tissue with 100 μl Matrigel per mouse) into NSG mice. 16D tumor-bearing mice were treated by oral gavage with 10 mg/kg/day of Enzalutamide in the vehicle (1% carboxymethyl cellulose, 0.5% Tween 80, and 5% dimethylsulfoxide) or the vehicle only, with a two-days-on/one-day-off schedule. |