Summary of project PR000205

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR000205. The data can be accessed directly via it's Project DOI: 10.21228/M8WK5Q This work is supported by NIH grant, U2C- DK119886.


Project ID: PR000205
Project DOI:doi: 10.21228/M8WK5Q
Project Title:Metabolomics of Neonatal Pulmonary Hypertension (in a Rat Model)
Project Type:Treatment and feeding study
Project Summary:This study aims to identify identify disrupted metabolic pathways and patterns of lung developent in a rat model of bronchopulmonary dysplasia and growth restriction. Pregnant Sprague Dawley rats (gestational day 15) were housed in plsatic cages under constant conditions. After 7-d acclimization period, litters were delivered and pups randomly distributed between litters of 10 pups (N, normal intake) or litters of 17 pups (R, restricted intake). Normal and restriced intake pups were exposed to 75% oxygen (O, oxygen) in a Plexiglass chamber or to 21% oxygen (A, room air) continuously for 14 days, with daily rotation of dams to avoid oxygen toxicity. Both plasma and lung tissue underwent metabolomics analysis.
Institute:University of California, Davis
Department:Department of Pediatrics, School of Medicine
Laboratory:Wedgwood lab
Last Name:Wedgwood
First Name:Stephen
Address:1002B, Research II, 4625 2nd Ave., Sacramento, CA 95817
Funding Source:National Institute of Health U24 DK092993

Summary of all studies in project PR000205

Study IDStudy TitleSpeciesInstituteAnalysis
(* : Contains Untargted data)
(* : Contains raw data)
ST000253 NIH WCMC Pilot & Feasibility Project: “Metabolomics of Neonatal Pulmonary Hypertension” Rattus norvegicus University of California, Davis MS 2015-09-14 1 32 Uploaded data (8.2M)*