Summary of project PR000269

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR000269. The data can be accessed directly via it's Project DOI: 10.21228/M81307 This work is supported by NIH grant, U2C- DK119886.


Project ID: PR000269
Project DOI:doi: 10.21228/M81307
Project Title:Metabolomics approach to allograft assessment in liver transplantation
Project Type:Retrospective analysis of biobank samples
Project Summary:Organ shortage is the primary limiting factor in liver transplantation and has led to expanded utilization of livers from marginal donors. Assessment of liver allograft quality is currently based on clinical factors such as donor age, cause of death, liver function, routine clinical laboratory values and extent of graft steatosis (fat content). Expanded utilization necessitates a more detailed assessment of liver allograft quality to guide decisions regarding suitability for transplantation. Using a metabolomics approach, we plan to capture molecular snapshots of the physiologic state of the graft and to elucidate biomarkers of allograft quality and graft function post-transplant.
Institute:Ochsner Multi-Organ Transplant Institute
Department:Abdominal Organ Transplantation
Last Name:Seal
First Name:John
Address:1514 Jefferson Highway, New Orleans, LA 70121
Funding Source:SECIM Pilot and Feasibility Award

Summary of all studies in project PR000269

Study IDStudy TitleSpeciesInstituteAnalysis
(* : Contains Untargted data)
(* : Contains raw data)
ST000337 Metabolomics Approach to Allograft Assessment in Liver Transplantation Homo sapiens Ochsner Multi-Organ Transplant Institute MS 2017-01-17 1 25 Uploaded data (2.9M)
ST000424 Metabolomics Approach to Allograft Assessment in Liver Transplantation (part II) Homo sapiens University of Florida MS* 2017-10-03 1 25 Uploaded data (13.4G)*