Summary of project PR000317
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000317. The data can be accessed directly via it's Project DOI: 10.21228/M87G7J This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR000317 |
| Project DOI: | doi: 10.21228/M87G7J |
| Project Title: | Metabolomic Profiling in Early Pregnancy using Pre-Diagnostic Sera from Women Who Developed Placental Abruption |
| Project Type: | Metabolomics |
| Project Summary: | Placental abruption is an ischemic placental disorder that results from the premature separation of the placenta from the wall of the uterus before delivery of the fetus. This disorder is associated with pre-term delivery, fetal death, maternal hemorrhagic shock, and renal failure. Several physiologic disturbances, such as oxidative stress, carbohydrate/fatty acid metabolism, and mitochondrial dysfunction, have been associated with ischemic placental disorder as well as with placental abruption. This preliminary study proposes to identify metabolites associated with incident placental abruption using existing serum and clinical data from a previously studied cohort. Metabolomics analysis will be carried out on maternal serum (51 cases and 51 controls) collected in early pregnancy (early second trimester). |
| Institute: | Harvard School of Public Health |
| Department: | Swedish Medical Center |
| Last Name: | Williams |
| First Name: | Michelle |
| Address: | 677 Huntington Ave. Kresge Room 905A, Boston, MA 02446 |
| Email: | mawilliams@hsph.harvard.edu |
| Phone: | (617) 432 - 6477 |
Summary of all studies in project PR000317
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST000405 | Metabolomic Profiling in Early Pregnancy using Pre-Diagnostic Sera from Women Who Developed Placental Abruption | Homo sapiens | RTI International | MS | 2017-05-27 | 1 | 111 | Uploaded data (11.9M)* |
