Summary of project PR000697
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000697. The data can be accessed directly via it's Project DOI: 10.21228/M8KH4V This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR000697 |
| Project DOI: | doi: 10.21228/M8KH4V |
| Project Title: | Development of a weaned pig model of enterotoxigenic E.coli-induced environmental enteropathy |
| Project Type: | Animal Model |
| Project Summary: | Environmental Enteropathy (EE) is a subclinical condition primarily effecting developing countries believed to be caused by chronic fecal-oral contamination. The condition is characterized by chronic gut inflammation, malabsorption, stunting of growth, stunted villi, and reduced efficacy of oral vaccines. Due to the similarity of the gastrointestinal tract and immune response of swine and humans, the piglet is an attractive model for studying this condition. In this present study, piglets were challenged with either a chronic or acute dose of pathogenic E.coli in an attempt to mimic the symptoms of EE over a 7 day trial period. Throughout the study a number of biological samples were collected for analysis and are presented here, including feces for untargeted metabolomics analysis. |
| Institute: | Texas A&M University |
| Department: | Animal Science |
| Laboratory: | Gill Lab |
| Last Name: | Boeckman |
| First Name: | Justin |
| Address: | 400 Bizzell Street, College Station, TX, 77843, USA |
| Email: | Jxboeckman@tamu.edu |
| Phone: | 4084893729 |
| Funding Source: | Bill and Melinda Gates Foundation |
| Publications: | In progress |
| Contributors: | Justin Boeckman, Sarah Sprayberry, Jason Gill, Todd Callaway |
Summary of all studies in project PR000697
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST001041 | Development of a weaned pig model of enterotoxigenic E.coli-induced environmental enteropathy | Sus scrofa | Texas A&M University | MS | 2018-10-10 | 1 | 47 | Uploaded data (274.1M) |
