Summary of project PR000726
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000726. The data can be accessed directly via it's Project DOI: 10.21228/M8TX0N This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR000726 |
| Project DOI: | doi: 10.21228/M8TX0N |
| Project Title: | Metabolomics of Colorectal Cancer in Malaysia |
| Project Summary: | Colorectal cancer (CRC) is one of the major leading cause of death in humans worldwide. In Malaysia, CRC is the fourth leading cause of death, covered 13.2% of new cancer diagnoses in Peninsular Malaysia in 2006. Causable factors are remaining unknown. Changes in dietary may alter colonic microbiome and mucosal immune microenvironment inducing colon oncogenesis. Previous investigation focused on mutagen production by colonic bacteria or their conversion of dietary procarcinogens into DNA-damaging molecules. Yet, no direct links between the metabolic activities of bacteria and sporadic CRC were identified. The objective of this study was to prospectively characterize the human colonic microbiome in CRC using metabolomic approache in Kuala Lumpur, Malaysia and to understand the functionality of the colonic microbiome and host-microbial interactions in CRC. |
| Institute: | University of Malaya |
| Department: | Medical Microbiology |
| Laboratory: | Helicobacter Research Laboratory, UM Marshall Centre |
| Last Name: | Loke |
| First Name: | Mun Fai |
| Address: | Department of Medical Microbiology, Faculty of Medicine, Kuala Lumpur, Federal Territory, 50603, Malaysia |
| Email: | lmunfai@gmail.com |
| Phone: | 83880014 |
Summary of all studies in project PR000726
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST001087 | Metabolomics and 16S rRNA sequencing of human colorectal cancers and adjacent mucosa | Homo sapiens | University of Malaya | MS* | 2018-12-11 | 1 | 68 | Uploaded data (4.1M) |
