Summary of project PR000823

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000823. The data can be accessed directly via it's Project DOI: 10.21228/M89D5Q This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

Project ID: PR000823
Project DOI:doi: 10.21228/M89D5Q
Project Title:Fish-oil supplementation in pregnancy, child metabolomics and asthma risk
Project Type:Untargeted metabolomics
Project Summary:We investigated potential metabolic mechanisms using untargeted liquid chromatography-mass spectrometry-based metabolomics on 577 plasma samples collected at age 6 months in the offspring of mothers participating in the n-3 LCPUFA randomised controlled trial. First, associations between the n-3 LCPUFA supplementation groups and child metabolite levels were investigated using univariate regression models and data-driven partial least square discriminant analyses (PLS-DA). Second, we analysed the association between the n-3 LCPUFA metabolomic profile and asthma development using Cox-regression. Third, we conducted mediation analyses to investigate whether the protective effect of n-3 LCPUFA on asthma was mediated via the metabolome.
Institute:University of Copenhagen
Department:Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital
Last Name:Rago
First Name:Daniela
Address:Ledreborg Alle 34, Gentofte, DK, 2820, Denmark
Email:daniela.rago@dbac.dk
Phone:+45-39777360

Summary of all studies in project PR000823

Study IDStudy TitleSpeciesInstituteAnalysis
(* : Contains Untargted data)		 Release
Date		VersionSamplesDownload
(* : Contains raw data)
ST001212 Fish-oil supplementation in pregnancy, child metabolomics and asthma risk Homo sapiens University of Copenhagen MS* 2019-09-23 1 577 Uploaded data (1M)
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