Summary of project PR000861
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000861. The data can be accessed directly via it's Project DOI: 10.21228/M8D392 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR000861 |
| Project DOI: | doi: 10.21228/M8D392 |
| Project Title: | Development and Characterisation of a Novel Class of Aroyl Guanidine Containing Anti-Trypanosomal Compounds |
| Project Summary: | The mode of action of a novel class of aroyl guanidine containing anti-Trypanosomal compounds was investigated using an unbiased metabolomics approach. Trypanosoma brucei parasites were incubated for five hours with the test compounds at 1 µM concentration. Analysis of cell pellets allowed reproducible detection of diverse metabolites from a range of metabolic pathways. |
| Institute: | Monash University |
| Last Name: | Creek |
| First Name: | Darren |
| Address: | Monash Institute of Pharmaceutical Sciences, 381 Royal Parade, Parkville, Melbourne, Victoria, 3052, Australia |
| Email: | darren.creek@monash.edu |
| Phone: | +61 (0) 3 9903 9249 |
Summary of all studies in project PR000861
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST001276 | Development and Characterisation of a Novel Class of Aroyl Guanidine Containing Anti-Trypanosomal Compounds | Trypanosoma brucei brucei | Monash University | MS | 2020-01-13 | 1 | 36 | Uploaded data (3.6G)* |
