Summary of project PR000884
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000884. The data can be accessed directly via it's Project DOI: 10.21228/M8DX2P This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR000884 |
| Project DOI: | doi: 10.21228/M8DX2P |
| Project Title: | TGFβ3 heterozygous mice |
| Project Type: | Mice nephropathy in lipotoxic model |
| Project Summary: | Transforming growth factor β (TGFβ) family comprises the main player in the development of fibrosis including three isoforms: TGFβ1, TGFβ2 and TGFβ3. TGFβ3 may play an antifibrotic role at the renal level, counteracting the role of TGFβ1, using a mouse model heterozygous for the TGFβ3 gene (TGFβ3+/-). Partial deletion of TGFβ3 causes in the mice albuminuria, loss of glomerular filtration rate, accelerated fibrosis, epithelial-to-mesenchymal transition and increment of glomerular basement membrane thickening. |
| Institute: | University Rey Juan Carlos |
| Department: | Basics Science of Health |
| Last Name: | Lanzon |
| First Name: | Borja |
| Address: | Avenida de Atenas S/N, Alcorcón, Madrid, 28922, Spain |
| Email: | borja.lanzon@urjc.es |
| Phone: | 663692554 |
Summary of all studies in project PR000884
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST001303 | TGF-Beta 3 heterozygous mice | Mus musculus | University Rey Juan Carlos | MS* | 2020-03-03 | 1 | 19 | Uploaded data (19.5G)* |
