Summary of project PR000900

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR000900. The data can be accessed directly via it's Project DOI: 10.21228/M8BX09 This work is supported by NIH grant, U2C- DK119886.


Project ID: PR000900
Project DOI:doi: 10.21228/M8BX09
Project Title:Effect of high-fat diet on serum lipidome in mice
Project Summary:We analyzed mouse serum samples from a mouse dietary intervention experiment. Briefly, C57BL/6 mice (n=44) were divided into 4 groups (n=11 per group) and fed High-fat diet (HFD), 1% deoxycholic acid (DCA) in drinking water, both, or left as control for 9 months. For quality control, 12 TQC samples and 2 blanks were also included in the analysis (total 58 samples and 6 groups). The two treatments were selected to demonstrate the ability of lipidomics to detect gross changes induced by HFD in the serum lipidome, as well as specific/minor changes induced by the secondary bile acid (DCA) through regulation of liver lipid metabolism.
Institute:QIMR Berghofer Medical Research Institute
Department:Precision & Systems Biomedicine
Last Name:Mohamed
First Name:Ahmed
Address:300 Herston Road, Herston, QLD, 4006, Australia

Summary of all studies in project PR000900

Study IDStudy TitleSpeciesInstituteAnalysis
(* : Contains Untargted data)
(* : Contains raw data)
ST001323 Effect of high-fat diet on serum lipidome in mice Mus musculus QIMR Berghofer Medical Research Institute MS 2020-03-20 1 58 Uploaded data (486.6M)*
ST001336 Effect of high-fat diet and bile acid treatment on serum and tissue lipidomes in mice Mus musculus QIMR Berghofer Medical Research Institute MS 2020-04-27 1 220 Uploaded data (19.3G)*