Summary of project PR001051
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001051. The data can be accessed directly via it's Project DOI: 10.21228/M8V702 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR001051 |
| Project DOI: | doi: 10.21228/M8V702 |
| Project Title: | Deletion of the diabetes candidate gene Slc16a13 in mice |
| Project Summary: | The metabolome of plasma and liver lysates of Slc16a13 knockout mice was analyzed. Genome-wide association studies identified SLC16A13 as novel target gene in type 2 diabetes. The SLC16A13 gene encodes for SLC16A13/MCT13, a member of the solute carrier 16 family of monocarboxylate transporters. So far, biology and physiological function of SLC16A13 is unknown. Deletion of Slc16a13 is hypothezised to affect intrahepatocellular monocarboxylate availability, that drives increased oxidative phosphorylation, while reducing hepatic lipid content, thereby attenuating hepatic insulin resistance. |
| Institute: | University of California, Davis |
| Department: | West Coast Metabolomics Center |
| Last Name: | Birkenfeld |
| First Name: | Andreas |
| Address: | Ottfried-Müller Str. 10 72076 Tübingen |
| Email: | Andreas.Birkenfeld@med.uni-tuebingen.de |
| Phone: | +49(0)7071 84 20257 |
Summary of all studies in project PR001051
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST001643 | Deletion of the diabetes candidate gene Slc16a13 in mice | Mus musculus | University of California, Davis | MS | 2021-04-01 | 1 | 24 | Uploaded data (247M)* |
