Summary of project PR001098
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001098. The data can be accessed directly via it's Project DOI: 10.21228/M8S40D This work is supported by NIH grant, U2C- DK119886. See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR001098 |
| Project DOI: | doi: 10.21228/M8S40D |
| Project Title: | Metabolomic Profiling of Atovaquone and Atovaquone-Like Resistant Lines |
| Project Summary: | Here we interrogated the in vitro metabolic effects of 4 drugs using ultra-high performance liquid chromatography mass-spectrometry (UHPLC-MS). The resulting metabolic fingerprints provide information on the parasite biochemical pathways affected by pharmacologic intervention. We interrogate the metabolic effects of 3 different parasite strains resistant to the drugs also tested. The metabolic effects were compared to their parent strain. The metabolic fingerprints provided show that certain biochemical pathways are affected by the change that arises due to resistance. |
| Institute: | Pennsylvania State University |
| Department: | Department of Biochemistry and Molecular Biology |
| Last Name: | Llinas |
| First Name: | Manuel |
| Address: | W122 Millennium Science Complex, Pollock Road, University Park, PA 16802 |
| Email: | manuel@psu.edu |
| Phone: | 814-867-3527 |
Summary of all studies in project PR001098
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST001714 | Metabolomic Profiling of Atovaquone and Atovaquone-like Resistance Lines | Plasmodium falciparum | Pennsylvania State University | MS | 2026-01-02 | 1 | 33 | Uploaded data (2.4G)* |
