Summary of project PR001129
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001129. The data can be accessed directly via it's Project DOI: 10.21228/M8RX1D This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR001129 |
| Project DOI: | doi: 10.21228/M8RX1D |
| Project Title: | Plasma metabolomics of diverse mouse strains infected with Plasmodium chabaudi |
| Project Summary: | To uncover links between metabolism and disease severity in murine malaria, we performed plasma metabolomics via Metabolon on eight inbred, Plasmodium chabaudi-infected mouse strains with diverse disease phenotypes. We sacrificed and collected plasma from >=3 mice per strain per day of acute infection alongside uninfected control mice (approximately days 5-12 depending on mouse strain). We collected disease severity data, e.g. weight loss, liver enzymes, and anemia, concurrently. Together, these data enable 1) a picture of strain-specific and conserved metabolic responses during acute malaria, and 2) a comparison between metabolic responses and disease severity. |
| Institute: | Stanford University |
| Department: | Microbiology & Immunology |
| Laboratory: | David Schneider |
| Last Name: | Schneider |
| First Name: | David |
| Address: | 299 Campus Drive |
| Email: | dschneid@stanford.edu |
| Phone: | 650-724-8064 |
Summary of all studies in project PR001129
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST001775 | Plasma metabolomics of diverse mouse strains infected with Plasmodium chabaudi | Mus musculus | Stanford University | MS | 2021-05-21 | 1 | 369 | Not available |
