Summary of project PR001263

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001263. The data can be accessed directly via it's Project DOI: 10.21228/M8FX3C This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

Project ID: PR001263
Project DOI:doi: 10.21228/M8FX3C
Project Title:Transcriptomic and lipidomic analysis unravels the response of Faecalibacterium prausnitzii to calcium palmitate
Project Summary:Infant formula is a suggested alternative to human milk if breastfeeding is not an option; vegetable oil blends are commonly used in infant formula (IF) to replace dairy fat, which can induce the formation of the poorly soluble soap calcium palmitate (CP) in the infant’s gut. Previously, we observed that CP at a low concentration of 0.01 mg/ml inhibits the growth of dominant infant bacteria such as Faecalibacterium prausnitzii both during the exponential phase as well as in the stationary phase. Here, we investigate the underlying mechanism of the CP inhibition on infant-gut bacteria using F. prausnitzii as a model by analysing its growth at a transcriptomic and lipidomic level.
Institute:University of Groningen
Last Name:Horvatovich
First Name:Péter
Address:Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands
Email:p.l.horvatovich@rug.nl
Phone:+31 (0)50 363 3341

Summary of all studies in project PR001263

Study IDStudy TitleSpeciesInstituteAnalysis
(* : Contains Untargted data)		 Release
Date		VersionSamplesDownload
(* : Contains raw data)
ST001987 Transcriptomic and lipidomic analysis unravels the response of Faecalibacterium prausnitzii to calcium palmitate Faecalibacterium prausnitzii University of Groningen MS* 2021-12-15 1 96 Uploaded data (11.4G)*
  logo