Summary of project PR001502
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001502. The data can be accessed directly via it's Project DOI: 10.21228/M8JD81 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR001502 |
| Project DOI: | doi: 10.21228/M8JD81 |
| Project Title: | Serine and lipid metabolism |
| Project Summary: | We analyzed hepatic polar and lipid metabolites in mice (C57BL/6J) in response to two dietary interventions. The first was: 1) low fat (LFD), 2) serine/glycine-free LFD (-SG LFD), high fat (HFD), and serine/glycine-free HFD (-SG HFD). And the second was: 1) low fat (LFD), high fat (HFD), serine/glycine-free HFD (-SG HFD), and serine/glycine-free HFD (-SG HFD) with myriocin (0.3 mg/kg every other day) treatment. The goal of the study was to determine the impact of dietary serine/glycine restriction and myriocin treatment on the hepatic lipidome. |
| Institute: | Salk Institute for Biological Studies |
| Department: | Molecular and Cell Biology Laboratory |
| Laboratory: | Metallo Lab |
| Last Name: | Handzlik |
| First Name: | Michal |
| Address: | 10010 N Torrey Pines Rd, La Jolla, California, 92037, USA |
| Email: | mhandzlik@salk.edu |
| Phone: | 2069601945 |
| Funding Source: | R01CA234245 |
Summary of all studies in project PR001502
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST002339 | Myriocin rescue of serine-associated hepatic lipid diversity | Mus musculus | Salk Institute for Biological Studies | MS | 2024-01-01 | 1 | 47 | Uploaded data (1.5G)* |
| ST002340 | Serine supplementation and hepatic and skin sphingolipid diversity | Mus musculus | Salk Institute for Biological Studies | MS | 2024-01-01 | 1 | 32 | Uploaded data (333M)* |
| ST002343 | The impact of myriocin and dietary serine restriction on paw skin sphingolipid diversity | Mus musculus | Salk Institute for Biological Studies | MS | 2024-01-01 | 1 | 47 | Uploaded data (474.6M)* |
| ST002344 | The impact of dietary serine/glycine restriction and myriocin treatment on hepatic sphingolipid diversity during prolonged high fat diet feeding. | Mus musculus | Salk Institute for Biological Studies | MS | 2024-01-01 | 1 | 78 | Uploaded data (809.5M)* |
