Summary of project PR001589
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001589. The data can be accessed directly via it's Project DOI: 10.21228/M89H8W This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Project ID: | PR001589 |
| Project DOI: | doi: 10.21228/M89H8W |
| Project Title: | Tryptophan metabolites in human serum |
| Project Type: | MS quantitative study |
| Project Summary: | Trp metabolites circulating in serum could provide insight into homeostatic activity of AHR, and we wished to know if the observations in mice could be replicated in humans. Previous work by our group identified AHR activators in human feces, yet it is not clear if these activators are also present in circulation. To address this question, we quantified Trp metabolites in human serum. To mitigate the variable effect of diet on metabolite profiles, we analyzed sera samples collected from study participants fed a defined diet. As with the previously discussed mouse sera, targeted metabolomics was performed on serum samples using LC-MS. |
| Institute: | The Pennsylvania State University |
| Last Name: | DONG |
| First Name: | FANGCONG |
| Address: | 309 Life Sciences Building, State college, PA, 16802, USA |
| Email: | fxd93@psu.edu |
| Phone: | 8146990203 |
Summary of all studies in project PR001589
| Study ID | Study Title | Species | Institute | Analysis(* : Contains Untargted data) | Release Date | Version | Samples | Download(* : Contains raw data) |
|---|---|---|---|---|---|---|---|---|
| ST002462 | Tryptophan metabolites in human sera on a defined diet | Homo sapiens | Pennsylvania State University | MS | 2023-02-06 | 1 | 50 | Uploaded data (786M)* |
