Summary of project PR001600

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR001600. The data can be accessed directly via it's Project DOI: 10.21228/M8W70C This work is supported by NIH grant, U2C- DK119886.


Project ID: PR001600
Project DOI:doi: 10.21228/M8W70C
Project Title:Human neutrophil metabolomics
Project Type:MS qualitative analysis
Project Summary:Severe COVID-19 is characterized by an increase in the number and changes in the function of innate immune cells including neutrophils. However, it is not known how the metabolome of immune cells changes in COVID-19 patients or how metabolic changes may contribute to immune dysfunction. To address these questions, we analyzed the metabolome of neutrophils from patients with severe or mild COVID-19, or healthy controls. We identified widespread dysregulation of neutrophil metabolism with disease progression including in amino acid, redox, and central carbon metabolism.
Institute:UT Southwestern Medical Center
Department:Children's Research Institute
Last Name:Li
First Name:Yafeng
Address:5323 Harry Hines Blvd, Children's Research Institute, Dallas, TX, 75309, USA

Summary of all studies in project PR001600

Study IDStudy TitleSpeciesInstituteAnalysis
(* : Contains Untargted data)
(* : Contains raw data)
ST002477 Neutrophil metabolomics in COVID-19 Homo sapiens UT Southwestern Medical Center MS 2023-02-26 1 89 Uploaded data (14.7G)*